caffeine has been researched along with Osteogenic Sarcoma in 25 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nine patients with osteosarcoma were treated by chemotherapy combined with caffeine and surgery." | 9.07 | Effect of chemotherapy combined with caffeine for osteosarcoma. ( Baba, H; Tomita, K; Tsuchiya, H; Ueda, Y; Yasutake, H; Yokogawa, A, 1992) |
| "The combination of o-rMETase and caffeine together with first-line chemotherapy was efficacious for drug-resistant osteosarcoma and has clinical potential in the treatment of this highly-resistant neoplasm." | 7.91 | Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma. ( Bouvet, M; Chawla, SP; Han, Q; Hayashi, K; Higuchi, T; Hoffman, RM; Igarashi, K; Kimura, H; Miwa, S; Miyake, K; Oshiro, H; Park, J; Razmjooei, S; Singh, SR; Sugisawa, N; Tan, Y; Tsuchiya, H; Yamamoto, N; Zhang, Z, 2019) |
| "This study was designed to evaluate whether the addition of caffeine, citrate, or caffeine citrate to cisplatin improved its cytocidal effect (cell survival, proliferation, and apoptosis) on human osteosarcoma (HOS), human fibrosarcoma (HT1080) and murine osteosarcoma (LM8) cell lines." | 7.91 | Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo. ( Abe, K; Hayashi, K; Takeuchi, A; Tsuchiya, H; Yamamoto, N, 2019) |
| "In this study, we performed combination treatment of caffeine and valproic acid on osteosarcoma cell lines in vitro and in spontaneous and experimental lung metastasis mouse models of osteosarcoma." | 7.85 | Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice. ( Hayashi, K; Hoffman, RM; Igarashi, K; Kawaguchi, K; Kimura, H; Kiyuna, T; Miwa, S; Murakami, T; Tsuchiya, H; Yamamoto, N, 2017) |
| " We subsequently tested the combination of valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, with caffeine on established human osteosarcoma cells in vitro." | 7.85 | Efficacy In Vitro of Caffeine and Valproic Acid on Patient-Derived Undifferentiated Pleomorphic Sarcoma and Rhabdomyosarcoma Cell Lines. ( Dry, SM; Eilber, FC; Hayashi, K; Hoffman, RM; Igarashi, K; Kawaguchi, K; Kimura, H; Kiyuna, T; Li, Y; Miwa, S; Murakami, T; Nelson, SD; Singh, AS; Tsuchiya, H; Yamamoto, N, 2017) |
| "Both valproic acid and caffeine caused concentration-dependent cell death of the osteosarcoma cell lines in vitro." | 7.83 | Non-toxic Efficacy of the Combination of Caffeine and Valproic Acid on Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models. ( Hayashi, K; Hoffman, RM; Igarashi, K; Kimura, H; Miwa, S; Takeuchi, A; Tsuchiya, H; Yamamoto, N, 2016) |
| "We previously reported that caffeine-assisted chemotherapy improved the treatment of malignant bone and soft tissue tumours such as osteosarcoma." | 7.78 | Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-κB and MAPK pathways. ( Hayashi, K; Igarashi, K; Kimura, H; Miwa, S; Nishida, H; Shirai, T; Sugimoto, N; Takeuchi, A; Tsuchiya, H; Yachie, A; Yamamoto, N, 2012) |
| " We investigated whether CPC implants containing anticancer drugs and caffeine, which enhance the cytocidal effect of anticancer drugs, would enhance their antitumor effects on rat osteosarcomas (SOSN2 cells)." | 7.77 | Potentiation of the antitumor effect of calcium phosphate cement containing anticancer drug and caffeine on rat osteosarcoma. ( Hayashi, K; Kawahara, M; Nishida, H; Shirai, T; Takeuchi, A; Tanzawa, Y; Tomita, K; Tsuchiya, H, 2011) |
| " Caffeine enhances the effect of cisplatin (CDDP) chemotherapy on osteosarcoma cells." | 7.75 | Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines. ( Tao, HM; Xie, XK; Yang, DS; Ye, ZM, 2009) |
| "We analyzed retrospectively overall survival and some prognostic factors for 41 patients with osteosarcoma/pulmonary metastases who were treated with caffeine-potentiated chemotherapy between 1990 and 2006." | 7.75 | Caffeine-potentiated chemotherapy for metastatic osteosarcoma. ( Hayashi, K; Kimura, H; Nishida, H; Ohnari, I; Shirai, T; Takeuchi, A; Tomita, K; Tsuchiya, H, 2009) |
| "To determine the enhancement effects of caffeine on chemotherapy of transplanted osteosarcoma in Fischer 344/N rats." | 7.73 | [Enhancement effect of caffeine on chemotherapy of osteosarcoma in Fischer 344/N rats]. ( Chen, J; Fan, SW; Gu, CL; Wan, SL, 2005) |
| "The authors report on intentional marginal excision for osteosarcoma in conjunction with caffeine assisted chemotherapy for the purpose of preservation of good limb function." | 7.70 | Marginal excision for osteosarcoma with caffeine assisted chemotherapy. ( Asada, N; Mori, Y; Tomita, K; Tsuchiya, H; Yamamoto, N, 1999) |
| "We treated three patients with osteosarcoma in extremity with intra-arterial combination chemotherapy using a regimen selected by succinate dehydrogenase inhibition chemosensitivity test, and used caffeine to enhance its effect." | 7.69 | [Intra-arterial combination chemotherapy using both regimen selected by chemosensitivity test and caffeine to increase effect for osteosarcoma in extremity]. ( Baba, H; Fujihara, A; Inoue, K; Isayama, T; Kanamiya, T; Maehara, Y; Ogata, K; Yoh, S; Yoshitake, K, 1994) |
| "A study on the effect of anti-tumor agents combined with caffeine on sarcoma cells was carried out by clonogenic assay." | 7.67 | [A study of the effect of anti-tumor agents combined with caffeine on established lines of human osteosarcoma cells and primary cultured human sarcoma cells by clonogenic assay]. ( Tomita, K; Tsuchiya, H, 1987) |
| "A nontoxic dose of caffeine enhanced the cytotoxicity of cisplatin in human osteosarcoma cells (OST strain)." | 7.67 | Enhancement of cytocidal and antitumor effect of cisplatin by caffeine in human osteosarcoma. ( Tomita, K; Tsuchiya, H, 1989) |
| "Caffeine can safely enhance the cytocidal effects of anticancer drugs through its DNA repair-inhibiting effect." | 5.35 | Impact of serum caffeine monitoring on adverse effects and chemotherapeutic responses to caffeine-potentiated chemotherapy for osteosarcoma. ( Hayashi, K; Kawahara, M; Miyamoto, K; Shirai, T; Takeuchi, A; Tomita, K; Tsuchiya, H; Yamamoto, N; Yamauchi, K, 2009) |
| "Nine patients with osteosarcoma were treated by chemotherapy combined with caffeine and surgery." | 5.07 | Effect of chemotherapy combined with caffeine for osteosarcoma. ( Baba, H; Tomita, K; Tsuchiya, H; Ueda, Y; Yasutake, H; Yokogawa, A, 1992) |
| "The combination of o-rMETase and caffeine together with first-line chemotherapy was efficacious for drug-resistant osteosarcoma and has clinical potential in the treatment of this highly-resistant neoplasm." | 3.91 | Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma. ( Bouvet, M; Chawla, SP; Han, Q; Hayashi, K; Higuchi, T; Hoffman, RM; Igarashi, K; Kimura, H; Miwa, S; Miyake, K; Oshiro, H; Park, J; Razmjooei, S; Singh, SR; Sugisawa, N; Tan, Y; Tsuchiya, H; Yamamoto, N; Zhang, Z, 2019) |
| "This study was designed to evaluate whether the addition of caffeine, citrate, or caffeine citrate to cisplatin improved its cytocidal effect (cell survival, proliferation, and apoptosis) on human osteosarcoma (HOS), human fibrosarcoma (HT1080) and murine osteosarcoma (LM8) cell lines." | 3.91 | Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo. ( Abe, K; Hayashi, K; Takeuchi, A; Tsuchiya, H; Yamamoto, N, 2019) |
| " We subsequently tested the combination of valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, with caffeine on established human osteosarcoma cells in vitro." | 3.85 | Efficacy In Vitro of Caffeine and Valproic Acid on Patient-Derived Undifferentiated Pleomorphic Sarcoma and Rhabdomyosarcoma Cell Lines. ( Dry, SM; Eilber, FC; Hayashi, K; Hoffman, RM; Igarashi, K; Kawaguchi, K; Kimura, H; Kiyuna, T; Li, Y; Miwa, S; Murakami, T; Nelson, SD; Singh, AS; Tsuchiya, H; Yamamoto, N, 2017) |
| "In this study, we performed combination treatment of caffeine and valproic acid on osteosarcoma cell lines in vitro and in spontaneous and experimental lung metastasis mouse models of osteosarcoma." | 3.85 | Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice. ( Hayashi, K; Hoffman, RM; Igarashi, K; Kawaguchi, K; Kimura, H; Kiyuna, T; Miwa, S; Murakami, T; Tsuchiya, H; Yamamoto, N, 2017) |
| "Both valproic acid and caffeine caused concentration-dependent cell death of the osteosarcoma cell lines in vitro." | 3.83 | Non-toxic Efficacy of the Combination of Caffeine and Valproic Acid on Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models. ( Hayashi, K; Hoffman, RM; Igarashi, K; Kimura, H; Miwa, S; Takeuchi, A; Tsuchiya, H; Yamamoto, N, 2016) |
| "In recent years, chemotherapy with caffeine has manifested potently high efficacy against osteosarcoma, although adverse effects have been observed." | 3.81 | Development of tumor-specific caffeine-potentiated chemotherapy using a novel drug delivery system with Span 80 nano-vesicles. ( Iwasaki, T; Kidani, T; Masumoto, J; Miura, H; Miyazaki, T; Nakamura, A; Nakata, H; Sakayama, K, 2015) |
| "We previously reported that caffeine-assisted chemotherapy improved the treatment of malignant bone and soft tissue tumours such as osteosarcoma." | 3.78 | Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-κB and MAPK pathways. ( Hayashi, K; Igarashi, K; Kimura, H; Miwa, S; Nishida, H; Shirai, T; Sugimoto, N; Takeuchi, A; Tsuchiya, H; Yachie, A; Yamamoto, N, 2012) |
| " We investigated whether CPC implants containing anticancer drugs and caffeine, which enhance the cytocidal effect of anticancer drugs, would enhance their antitumor effects on rat osteosarcomas (SOSN2 cells)." | 3.77 | Potentiation of the antitumor effect of calcium phosphate cement containing anticancer drug and caffeine on rat osteosarcoma. ( Hayashi, K; Kawahara, M; Nishida, H; Shirai, T; Takeuchi, A; Tanzawa, Y; Tomita, K; Tsuchiya, H, 2011) |
| " Caffeine enhances the effect of cisplatin (CDDP) chemotherapy on osteosarcoma cells." | 3.75 | Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines. ( Tao, HM; Xie, XK; Yang, DS; Ye, ZM, 2009) |
| "We analyzed retrospectively overall survival and some prognostic factors for 41 patients with osteosarcoma/pulmonary metastases who were treated with caffeine-potentiated chemotherapy between 1990 and 2006." | 3.75 | Caffeine-potentiated chemotherapy for metastatic osteosarcoma. ( Hayashi, K; Kimura, H; Nishida, H; Ohnari, I; Shirai, T; Takeuchi, A; Tomita, K; Tsuchiya, H, 2009) |
| "To determine the enhancement effects of caffeine on chemotherapy of transplanted osteosarcoma in Fischer 344/N rats." | 3.73 | [Enhancement effect of caffeine on chemotherapy of osteosarcoma in Fischer 344/N rats]. ( Chen, J; Fan, SW; Gu, CL; Wan, SL, 2005) |
| "The authors report on intentional marginal excision for osteosarcoma in conjunction with caffeine assisted chemotherapy for the purpose of preservation of good limb function." | 3.70 | Marginal excision for osteosarcoma with caffeine assisted chemotherapy. ( Asada, N; Mori, Y; Tomita, K; Tsuchiya, H; Yamamoto, N, 1999) |
| "We treated three patients with osteosarcoma in extremity with intra-arterial combination chemotherapy using a regimen selected by succinate dehydrogenase inhibition chemosensitivity test, and used caffeine to enhance its effect." | 3.69 | [Intra-arterial combination chemotherapy using both regimen selected by chemosensitivity test and caffeine to increase effect for osteosarcoma in extremity]. ( Baba, H; Fujihara, A; Inoue, K; Isayama, T; Kanamiya, T; Maehara, Y; Ogata, K; Yoh, S; Yoshitake, K, 1994) |
| " In this study we discussed the combined effects of CDDP and caffeine or pentoxifylline using human osteosarcoma cells (OST strain)." | 3.67 | [DNA repair and drug resistance: enhancement of the effects of anticancer agents by DNA repair inhibitors]. ( Sasaki, T; Tomita, K; Tsuchiya, H, 1989) |
| "A nontoxic dose of caffeine enhanced the cytotoxicity of cisplatin in human osteosarcoma cells (OST strain)." | 3.67 | Enhancement of cytocidal and antitumor effect of cisplatin by caffeine in human osteosarcoma. ( Tomita, K; Tsuchiya, H, 1989) |
| "A study on the effect of anti-tumor agents combined with caffeine on sarcoma cells was carried out by clonogenic assay." | 3.67 | [A study of the effect of anti-tumor agents combined with caffeine on established lines of human osteosarcoma cells and primary cultured human sarcoma cells by clonogenic assay]. ( Tomita, K; Tsuchiya, H, 1987) |
| "Gambogic acid (GA) has been wildly studied to show potent anti-tumor effects in vivo and in vitro." | 1.36 | Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway. ( Guo, QL; Ha, J; Hu, R; Lu, N; Qi, Q; Rong, JJ; Song, XM; Tao, L; You, QD, 2010) |
| "Caffeine can safely enhance the cytocidal effects of anticancer drugs through its DNA repair-inhibiting effect." | 1.35 | Impact of serum caffeine monitoring on adverse effects and chemotherapeutic responses to caffeine-potentiated chemotherapy for osteosarcoma. ( Hayashi, K; Kawahara, M; Miyamoto, K; Shirai, T; Takeuchi, A; Tomita, K; Tsuchiya, H; Yamamoto, N; Yamauchi, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 11 (44.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ženata, O | 1 |
| Marcalíková, A | 1 |
| Vrzal, R | 1 |
| Higuchi, T | 1 |
| Oshiro, H | 1 |
| Miyake, K | 1 |
| Sugisawa, N | 1 |
| Han, Q | 1 |
| Tan, Y | 1 |
| Park, J | 1 |
| Zhang, Z | 1 |
| Razmjooei, S | 1 |
| Yamamoto, N | 10 |
| Hayashi, K | 11 |
| Kimura, H | 7 |
| Miwa, S | 6 |
| Igarashi, K | 6 |
| Bouvet, M | 1 |
| Chawla, SP | 1 |
| Singh, SR | 1 |
| Tsuchiya, H | 18 |
| Hoffman, RM | 4 |
| Kawaguchi, K | 2 |
| Kiyuna, T | 2 |
| Murakami, T | 2 |
| Nelson, SD | 1 |
| Dry, SM | 1 |
| Li, Y | 1 |
| Singh, AS | 1 |
| Eilber, FC | 1 |
| Abe, K | 1 |
| Takeuchi, A | 8 |
| Shirai, T | 5 |
| Nishida, H | 4 |
| Tanzawa, Y | 2 |
| Inatani, H | 1 |
| Shimozaki, S | 1 |
| Kato, T | 1 |
| Nakata, H | 1 |
| Miyazaki, T | 1 |
| Iwasaki, T | 1 |
| Nakamura, A | 1 |
| Kidani, T | 1 |
| Sakayama, K | 1 |
| Masumoto, J | 1 |
| Miura, H | 1 |
| Yamauchi, K | 1 |
| Kawahara, M | 2 |
| Miyamoto, K | 1 |
| Tomita, K | 11 |
| Ohnari, I | 1 |
| Xie, XK | 1 |
| Yang, DS | 1 |
| Ye, ZM | 1 |
| Tao, HM | 1 |
| Rong, JJ | 1 |
| Hu, R | 1 |
| Song, XM | 1 |
| Ha, J | 1 |
| Lu, N | 1 |
| Qi, Q | 1 |
| Tao, L | 1 |
| You, QD | 1 |
| Guo, QL | 1 |
| Sugimoto, N | 1 |
| Yachie, A | 1 |
| Chen, J | 1 |
| Gu, CL | 1 |
| Wan, SL | 1 |
| Fan, SW | 1 |
| Spangler, JG | 1 |
| Yoh, S | 1 |
| Isayama, T | 1 |
| Yoshitake, K | 1 |
| Fujihara, A | 1 |
| Kanamiya, T | 1 |
| Ogata, K | 1 |
| Inoue, K | 1 |
| Maehara, Y | 1 |
| Baba, H | 2 |
| Mori, Y | 1 |
| Asada, N | 1 |
| Morinaga, T | 1 |
| Taki, J | 1 |
| Sumiya, H | 1 |
| Matsui, O | 1 |
| Yasutake, H | 1 |
| Yokogawa, A | 1 |
| Ueda, Y | 1 |
| Sasaki, T | 1 |
2 trials available for caffeine and Osteogenic Sarcoma
| Article | Year |
|---|---|
Functional outcome in patients with osteosarcoma around the knee joint treated by minimised surgery.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Child; | 2008 |
Effect of chemotherapy combined with caffeine for osteosarcoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Calcane | 1992 |
23 other studies available for caffeine and Osteogenic Sarcoma
| Article | Year |
|---|---|
The Effect of Caffeine on Calcitriol-Inducible Vitamin D Receptor-Controlled Gene Expression in Intestinal and Osteoblastic Cells.
Topics: Caffeine; Calcitriol; Cell Line, Tumor; Gene Expression Regulation; Humans; Osteoblasts; Osteosarcom | 2019 |
Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Caffeine; Carbon-Sulfur Lyases; Cisp | 2019 |
Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Cell Death; Cell | 2017 |
Efficacy In Vitro of Caffeine and Valproic Acid on Patient-Derived Undifferentiated Pleomorphic Sarcoma and Rhabdomyosarcoma Cell Lines.
Topics: Apoptosis; Caffeine; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Histone Deacetylase Inhib | 2017 |
Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Caffeine; Cell Cycle Checkpoints; Cell Li | 2019 |
Late recurrence of osteosarcoma: a report of two cases.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Child; Combine | 2014 |
Development of tumor-specific caffeine-potentiated chemotherapy using a novel drug delivery system with Span 80 nano-vesicles.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Benzoates; Bone | 2015 |
Non-toxic Efficacy of the Combination of Caffeine and Valproic Acid on Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Caspase 3; Caspas | 2016 |
Impact of serum caffeine monitoring on adverse effects and chemotherapeutic responses to caffeine-potentiated chemotherapy for osteosarcoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Caffeine; Child; Chil | 2009 |
Caffeine-potentiated chemotherapy for metastatic osteosarcoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone | 2009 |
Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines.
Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Caffeine; Cell Cycle; Cell Line, Tumor; Cell Prolife | 2009 |
Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway.
Topics: Androstadienes; Antineoplastic Agents; Bone Neoplasms; Caffeine; CDC2 Protein Kinase; Cell Cycle; Ce | 2010 |
Potentiation of the antitumor effect of calcium phosphate cement containing anticancer drug and caffeine on rat osteosarcoma.
Topics: Animals; Antineoplastic Agents; Bone Cements; Bone Neoplasms; Caffeine; Calcium Phosphates; Coated M | 2011 |
Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-κB and MAPK pathways.
Topics: Apoptosis; Bone Neoplasms; Caffeine; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; MAP | 2012 |
[Enhancement effect of caffeine on chemotherapy of osteosarcoma in Fischer 344/N rats].
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Caffeine; Cisplatin; Drug Synergism; Neoplasm Transp | 2005 |
Bone biology and physiology: implications for novel osteoblastic osteosarcoma treatments?
Topics: Bone Neoplasms; Bone Remodeling; Caffeine; Calcium; Cell Line, Tumor; Cyclic AMP; Cytokines; Humans; | 2008 |
[Intra-arterial combination chemotherapy using both regimen selected by chemosensitivity test and caffeine to increase effect for osteosarcoma in extremity].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Cyclophosphami | 1994 |
Marginal excision for osteosarcoma with caffeine assisted chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Bone Transplantation; Caffeine; Child; Cis | 1999 |
Effect of myocutaneous inflammatory changes caused by intra-arterial chemotherapy on the outcome of patients who undergo limb-saving surgery.
Topics: Adolescent; Adult; Antineoplastic Agents; Bone Neoplasms; Caffeine; Child; Combined Modality Therapy | 2001 |
[DNA repair and drug resistance: enhancement of the effects of anticancer agents by DNA repair inhibitors].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Cell Division; | 1989 |
Enhancement of cytocidal and antitumor effect of cisplatin by caffeine in human osteosarcoma.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Caffeine; Cell Cycle; Cell Survival; Cells, Cultured | 1989 |
[A study of the effect of anti-tumor agents combined with caffeine on established lines of human osteosarcoma cells and primary cultured human sarcoma cells by clonogenic assay].
Topics: Antineoplastic Agents; Bone Neoplasms; Caffeine; Cell Line; Colony-Forming Units Assay; Humans; Oste | 1987 |
[The combined effect of anti-tumor agents with caffeine or calcium channel blockers on sarcoma cells by clonogenic assay].
Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeine; Calcium Channel Blockers; Colony-Forming U | 1987 |