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caffeine and Osteoarthritis

caffeine has been researched along with Osteoarthritis in 14 studies

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
"Our previous study reported that prenatal caffeine exposure (PCE) could induce chondrodysplasia and increase the susceptibility to osteoarthritis in offspring rats."8.12Intrauterine programming of cartilaginous 11β-HSD2 induced by corticosterone and caffeine mediated susceptibility to adult osteoarthritis. ( Chen, L; Gao, H; He, H; Li, B; Magdaloud, J; Shi, H; Wang, H; Wu, Z, 2022)
"Our previous studies confirmed that prenatal caffeine exposure (PCE) could induce susceptibility to osteoarthritis in adult offspring rats due to poor chondrocyte differentiation, but its mechanism remains to be further investigated."7.96Subchondral bone dysplasia mediates susceptibility to osteoarthritis in female adult offspring rats induced by prenatal caffeine exposure. ( Chen, L; Magdalou, J; Tan, Y; Wang, H; Wen, Y; Xiao, H; Xie, X, 2020)
"Our previous in vivo studies showed that prenatal caffeine exposure (PCE) could restrain the development of chondrogenesis, which may delay fetal articular cartilage development and increase susceptibility to osteoarthritis in adults."7.88Prenatal caffeine exprosure increases adult female offspring rat's susceptibility to osteoarthritis via low-functional programming of cartilage IGF-1 with histone acetylation. ( Chen, L; Li, J; Lu, K; Magdalou, J; Ni, Q; Tan, Y; Wang, H; Zhao, Z, 2018)
"Our previous study reported that prenatal caffeine exposure (PCE) could induce chondrodysplasia and increase the susceptibility to osteoarthritis in offspring rats."4.12Intrauterine programming of cartilaginous 11β-HSD2 induced by corticosterone and caffeine mediated susceptibility to adult osteoarthritis. ( Chen, L; Gao, H; He, H; Li, B; Magdaloud, J; Shi, H; Wang, H; Wu, Z, 2022)
"Our previous studies confirmed that prenatal caffeine exposure (PCE) could induce susceptibility to osteoarthritis in adult offspring rats due to poor chondrocyte differentiation, but its mechanism remains to be further investigated."3.96Subchondral bone dysplasia mediates susceptibility to osteoarthritis in female adult offspring rats induced by prenatal caffeine exposure. ( Chen, L; Magdalou, J; Tan, Y; Wang, H; Wen, Y; Xiao, H; Xie, X, 2020)
"Our previous in vivo studies showed that prenatal caffeine exposure (PCE) could restrain the development of chondrogenesis, which may delay fetal articular cartilage development and increase susceptibility to osteoarthritis in adults."3.88Prenatal caffeine exprosure increases adult female offspring rat's susceptibility to osteoarthritis via low-functional programming of cartilage IGF-1 with histone acetylation. ( Chen, L; Li, J; Lu, K; Magdalou, J; Ni, Q; Tan, Y; Wang, H; Zhao, Z, 2018)
"A survey of 763 patients with rheumatoid arthritis and 145 with osteoarthritis in six clinics in New Zealand showed no association between aspirin intake and a score designed to detect analgesic nephropathy."3.65Aspirin and the kidney. New Zealand Rheumatism Association Study. ( , 1974)
"Osteoarthritis is associated with intrauterine growth retardation (IUGR) and abnormal glucose metabolism."1.56Programming changes in GLUT1 mediated the accumulation of AGEs and matrix degradation in the articular cartilage of female adult rats after prenatal caffeine exposure. ( Hui, H; Hui, W; Liang, L; Liao-Bin, C; Lin-Long, W; Qing-Xian, L; Yi-Zhong, W, 2020)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's1 (7.14)24.3611
2020's4 (28.57)2.80

Authors

AuthorsStudies
Shi, H1
Li, B1
Gao, H1
He, H1
Wu, Z1
Magdaloud, J1
Wang, H4
Chen, L4
Qing-Xian, L1
Lin-Long, W1
Yi-Zhong, W1
Liang, L1
Hui, H1
Liao-Bin, C1
Hui, W1
Xie, X1
Tan, Y3
Xiao, H2
Wen, Y1
Magdalou, J3
Li, J2
Luo, H1
Ni, Q2
He, C1
Lu, K1
Zhao, Z1
GESELL-PAYER, A1
SERVERDUPUY, JM1
FUCHS, M1
BLUMENTHAL, LS1
Perlík, F1
Krauze, J1
Kuntz, D1
Brossel, R1
Gerzner, LF1
Thorpe, P1

Trials

3 trials available for caffeine and Osteoarthritis

ArticleYear
[Clinical evaluation of analgesics].
    Casopis lekaru ceskych, 1984, Jan-20, Volume: 123, Issue:3

    Topics: Adult; Aged; Analgesics; Antipyrine; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Comb

1984
[Analgesic effect and clinical tolerability of the combination of paracetamol 500 mg and caffeine 50 mg versus paracetamol 400 mg and dextropropoxyphene 30 mg in back pain].
    Presse medicale (Paris, France : 1983), 1996, Sep-07, Volume: 25, Issue:25

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Back Pa

1996
An assessment of "Fiorinal" and FIPA in painful conditions of the hands.
    The Medical journal of Australia, 1970, Aug-15, Volume: 2, Issue:7

    Topics: Acetaminophen; Adult; Aged; Analgesics; Analysis of Variance; Arthritis, Rheumatoid; Aspirin; Caffei

1970

Other Studies

11 other studies available for caffeine and Osteoarthritis

ArticleYear
Intrauterine programming of cartilaginous 11β-HSD2 induced by corticosterone and caffeine mediated susceptibility to adult osteoarthritis.
    Ecotoxicology and environmental safety, 2022, Jul-01, Volume: 239

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aggrecans; Animals; Caffeine; Cartilage; Corticosterone

2022
Programming changes in GLUT1 mediated the accumulation of AGEs and matrix degradation in the articular cartilage of female adult rats after prenatal caffeine exposure.
    Pharmacological research, 2020, Volume: 151

    Topics: Animals; Animals, Newborn; Caffeine; Cartilage, Articular; Female; Glucose Transporter Type 1; Glyca

2020
Subchondral bone dysplasia mediates susceptibility to osteoarthritis in female adult offspring rats induced by prenatal caffeine exposure.
    Toxicology letters, 2020, Mar-15, Volume: 321

    Topics: Age Factors; Animals; Bone Diseases, Developmental; Caffeine; Cartilage, Articular; Cell Differentia

2020
GR/HDAC2/TGFβR1 pathway contributes to prenatal caffeine induced-osteoarthritis susceptibility in male adult offspring rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 140

    Topics: Animals; Caffeine; Disease Susceptibility; Female; Histone Deacetylase 2; Male; Osteoarthritis; Preg

2020
Prenatal caffeine exprosure increases adult female offspring rat's susceptibility to osteoarthritis via low-functional programming of cartilage IGF-1 with histone acetylation.
    Toxicology letters, 2018, Oct-01, Volume: 295

    Topics: Acetylation; Aggrecans; Animals; Caffeine; Cartilage, Articular; Cells, Cultured; Central Nervous Sy

2018
[Impletol therapy of inflammatory processes and arthroses of the extremities].
    Hippokrates, 1960, Mar-15, Volume: 31

    Topics: Caffeine; Disease; Drug Combinations; Extremities; Humans; Joint Diseases; Osteoarthritis; Procaine

1960
[THE CUFF METHOD FOR THE ANTALGIC EVALUATION OF DIFFERENT DRUGS].
    El Dia medico, 1963, Sep-05, Volume: 35

    Topics: Aminopyrine; Arthritis; Arthritis, Rheumatoid; Aspirin; Caffeine; Gout; Osteoarthritis; Phenobarbita

1963
ANALGESIC COMBINATION IN HEADACHE.
    Headache, 1965, Volume: 5

    Topics: Analgesics; Arthritis; Aspirin; Back Pain; Caffeine; Cervical Vertebrae; Drug Therapy; Headache; Hum

1965
[Satisfactory but short-lasting effects of the treatment of coxarthrosis with injections of Impletol Depot Bayer].
    Reumatologia, 1983, Volume: 21, Issue:2

    Topics: Aged; Caffeine; Delayed-Action Preparations; Drug Combinations; Female; Follow-Up Studies; Hip Joint

1983
Aspirin and the kidney. New Zealand Rheumatism Association Study.
    British medical journal, 1974, Mar-30, Volume: 1, Issue:5908

    Topics: Acetaminophen; Adult; Arthritis, Rheumatoid; Aspirin; Caffeine; Codeine; Drug Synergism; Female; Hum

1974
Management of intractable pain by neural therapy.
    The Medical journal of Australia, 1970, May-23, Volume: 1, Issue:21

    Topics: Adult; Aged; Caffeine; Cicatrix; Dyspepsia; Female; Humans; Intermittent Claudication; Male; Middle

1970