caffeine has been researched along with Orphan Diseases in 6 studies
Orphan Diseases: Rare diseases that have not been well studied.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A physiologically based pharmacokinetic (PBPK) model was used to simulate the impact of elevated levels of interleukin (IL)-6 on the exposure of several orally administered cytochrome P450 (CYP) probe substrates (caffeine, S-warfarin, omeprazole, dextromethorphan, midazolam, and simvastatin)." | 1.51 | Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations. ( Ducray, PS; Endo-Tsukude, C; Gardner, I; Gill, KL; Hatley, OJ; Machavaram, KK; Parrott, N; Terao, K, 2019) |
| "At the ED, she presented an episode of presyncope followed by agitation." | 1.48 | Dangerous mistake: an accidental caffeine overdose. ( Andrade, A; Fernandes, M; Pedro, M; Sousa, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrade, A | 1 |
| Sousa, C | 1 |
| Pedro, M | 1 |
| Fernandes, M | 1 |
| Machavaram, KK | 1 |
| Endo-Tsukude, C | 1 |
| Terao, K | 1 |
| Gill, KL | 1 |
| Hatley, OJ | 1 |
| Gardner, I | 1 |
| Parrott, N | 1 |
| Ducray, PS | 1 |
| HOLT, KE | 1 |
| Manni, R | 1 |
| Sances, G | 1 |
| Terzaghi, M | 1 |
| Ghiotto, N | 1 |
| Nappi, G | 1 |
| de Barros, CM | 1 |
| Papoila, AL | 1 |
| Schmidt, A | 1 |
| Karlson-Stiber, C | 1 |
1 trial available for caffeine and Orphan Diseases
| Article | Year |
|---|---|
Hypnic headache: PSG evidence of both REM- and NREM-related attacks.
Topics: Age of Onset; Aged; Aged, 80 and over; Brain; Caffeine; Central Nervous System Stimulants; Cinnarizi | 2004 |
5 other studies available for caffeine and Orphan Diseases
| Article | Year |
|---|---|
Dangerous mistake: an accidental caffeine overdose.
Topics: Acidosis; Administration, Intravenous; Adult; Aftercare; Anti-Arrhythmia Agents; Caffeine; Dietary S | 2018 |
Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations.
Topics: Administration, Oral; Adult; Caffeine; Clinical Trials as Topic; Computer Simulation; Cytochrome P-4 | 2019 |
The separation of acetylsalicylic acid, acetophenetidin, and caffeine.
Topics: Aspirin; Caffeine; Phenacetin; Rare Diseases; Retinal Degeneration; Retinal Detachment; Salicylates | 1946 |
Therapeutic profile of orphan medicines.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Antineoplastic Agents; Bosentan; Caffeine; Central | 2007 |
Caffeine poisoning and lactate rise: an overlooked toxic effect?
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidotes; Anxiety; Caffeine; Central | 2008 |