caffeine has been researched along with Neural Tube Defects in 11 studies
Neural Tube Defects: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Investigations of maternal caffeine intake and neural tube defects (NTDs) have not considered genetic influences." | 7.76 | Caffeine, selected metabolic gene variants, and risk for neural tube defects. ( Browne, ML; Burns, TL; Druschel, CM; Murray, JC; Olney, RS; Romitti, PA; Schmidt, RJ, 2010) |
| "Associations between maternal caffeine consumption and neural tube defects (NTDs) by type of NTD (anencephaly, spina bifida, or encephalocele) were examined using data from the National Birth Defects Prevention Study (NBDPS)." | 7.75 | Maternal caffeine consumption and risk of neural tube defects. ( Browne, ML; Burns, TL; Druschel, CM; Olney, RS; Romitti, PA; Schmidt, RJ, 2009) |
| "Alcohol and caffeine consumption during pregnancy are risk factors for fetal outcome." | 7.67 | Neural tube defects in early rat embryos following maternal treatment with ethanol and caffeine. ( Persaud, TV; Ross, CP, 1989) |
| " However, postimplantation embryo development assessed on Day 12 of gestation revealed that caffeine exposure of 15 and 30 mg kg(-1) significantly reduced, at both dosage levels, somite number and the extent of neural tube closure." | 5.30 | Maternal caffeine consumption during pregnancy does not affect preimplantation development but delays early postimplantation growth in rat embryos. ( Jacombs, A; Loupis, A; Pollard, I; Ryan, J, 1999) |
| "Investigations of maternal caffeine intake and neural tube defects (NTDs) have not considered genetic influences." | 3.76 | Caffeine, selected metabolic gene variants, and risk for neural tube defects. ( Browne, ML; Burns, TL; Druschel, CM; Murray, JC; Olney, RS; Romitti, PA; Schmidt, RJ, 2010) |
| "Associations between maternal caffeine consumption and neural tube defects (NTDs) by type of NTD (anencephaly, spina bifida, or encephalocele) were examined using data from the National Birth Defects Prevention Study (NBDPS)." | 3.75 | Maternal caffeine consumption and risk of neural tube defects. ( Browne, ML; Burns, TL; Druschel, CM; Olney, RS; Romitti, PA; Schmidt, RJ, 2009) |
| "Alcohol and caffeine consumption during pregnancy are risk factors for fetal outcome." | 3.67 | Neural tube defects in early rat embryos following maternal treatment with ethanol and caffeine. ( Persaud, TV; Ross, CP, 1989) |
| " However, postimplantation embryo development assessed on Day 12 of gestation revealed that caffeine exposure of 15 and 30 mg kg(-1) significantly reduced, at both dosage levels, somite number and the extent of neural tube closure." | 1.30 | Maternal caffeine consumption during pregnancy does not affect preimplantation development but delays early postimplantation growth in rat embryos. ( Jacombs, A; Loupis, A; Pollard, I; Ryan, J, 1999) |
| "Caffeine (25 mg/kg) was administered on gestation day (g." | 1.29 | In utero exposure to caffeine causes delayed neural tube closure in rat embryos. ( Pollard, I; Wilkinson, JM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, RJ | 2 |
| Romitti, PA | 2 |
| Burns, TL | 2 |
| Browne, ML | 2 |
| Druschel, CM | 2 |
| Olney, RS | 2 |
| Murray, JC | 1 |
| Cavalli, P | 1 |
| Cavallari, U | 1 |
| Unfer, V | 1 |
| Tonni, G | 1 |
| Gilani, SH | 1 |
| Giovinazzo, JJ | 1 |
| Persaud, TV | 2 |
| Renwick, JH | 1 |
| Rosenberg, L | 1 |
| Mitchell, AA | 1 |
| Shapiro, S | 1 |
| Slone, D | 1 |
| Lee, H | 1 |
| Nagele, RG | 1 |
| Pietrolungo, JF | 1 |
| Wilkinson, JM | 1 |
| Pollard, I | 2 |
| Marret, S | 1 |
| Gressens, P | 1 |
| Van-Maele-Fabry, G | 1 |
| Picard, J | 1 |
| Evrard, P | 1 |
| Jacombs, A | 1 |
| Ryan, J | 1 |
| Loupis, A | 1 |
| Ross, CP | 1 |
1 trial available for caffeine and Neural Tube Defects
| Article | Year |
|---|---|
Selected birth defects in relation to caffeine-containing beverages.
Topics: Abnormalities, Drug-Induced; Beverages; Caffeine; Cleft Lip; Cleft Palate; Clinical Trials as Topic; | 1982 |
10 other studies available for caffeine and Neural Tube Defects
| Article | Year |
|---|---|
Maternal caffeine consumption and risk of neural tube defects.
Topics: Caffeine; Case-Control Studies; Female; Humans; Maternal Exposure; Neural Tube Defects; Pregnancy; R | 2009 |
Caffeine, selected metabolic gene variants, and risk for neural tube defects.
Topics: Acetylation; Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Case-Control Studies; Cytoc | 2010 |
Caffeine intake and risk of neural tube defects.
Topics: Caffeine; Female; Humans; Maternal Exposure; Neural Tube Defects; Pregnancy; Risk Factors | 2011 |
Embryopathic effects of caffeine in the chick.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Chick Embryo; Hemorrhage; Intestines; Microphthalmos | 1983 |
Food and malformation.
Topics: Abnormalities, Drug-Induced; Caffeine; Congenital Abnormalities; Female; Fetal Alcohol Spectrum Diso | 1982 |
Toxic and teratologic effects of caffeine on explanted early chick embryos.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Caffeine; Chick Embryo; Culture Techniques; Dose-Respon | 1982 |
In utero exposure to caffeine causes delayed neural tube closure in rat embryos.
Topics: Animals; Caffeine; Embryonic and Fetal Development; Female; Neural Tube Defects; Rats; Rats, Sprague | 1994 |
Caffeine-induced disturbances of early neurogenesis in whole mouse embryo cultures.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Embryo, Mammalian; Embryonic and Fetal Development; | 1997 |
Maternal caffeine consumption during pregnancy does not affect preimplantation development but delays early postimplantation growth in rat embryos.
Topics: Animals; Blastocyst; Caffeine; Embryonic and Fetal Development; Embryonic Development; Female; Fetal | 1999 |
Neural tube defects in early rat embryos following maternal treatment with ethanol and caffeine.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Central Nervous System; Ethanol; Female; Neural Tube | 1989 |