Page last updated: 2024-10-24

caffeine and Nervous System Disorders

caffeine has been researched along with Nervous System Disorders in 14 studies

Research Excerpts

ExcerptRelevanceReference
"Growth, neurologic, and ophthalmologic assessments were done in 21 low-birth-weight infants given caffeine for neonatal apnea and in 21 matched control infants."7.66Sequelae of caffeine treatment in preterm infants with apnea. ( Aranda, JV; Gunn, TR; Metrakos, K; Riley, P; Willis, D, 1979)
"Numerous case reports have documented that phenylpropanolamine (PPA) stimulates the central nervous system with symptoms ranging from anxiety and hallucinations to grand mal seizures produced by overdoses."3.67Phenylpropanolamine potentiates caffeine neurotoxicity in rats. ( Walker, JS, 1989)
"Theophylline can cause life-threatening seizures when administered in excessive doses."3.67Caffeine as a potential risk factor for theophylline neurotoxicity. ( Levy, G; Yasuhara, M, 1988)
"Growth, neurologic, and ophthalmologic assessments were done in 21 low-birth-weight infants given caffeine for neonatal apnea and in 21 matched control infants."3.66Sequelae of caffeine treatment in preterm infants with apnea. ( Aranda, JV; Gunn, TR; Metrakos, K; Riley, P; Willis, D, 1979)
"Higher EEG theta activity related to sleep deprivation was observed in mutated TNF-α, PER3, and COMT carriers, in the placebo condition particularly."3.01Genetic Determinants of Neurobehavioral Responses to Caffeine Administration during Sleep Deprivation: A Randomized, Cross Over Study (NCT03859882). ( Bourrilhon, C; Chennaoui, M; Drogou, C; Erblang, M; Erkel, MC; Gomez-Merino, D; Guillard, M; Léger, D; Quiquempoix, M; Rabat, A; Sauvet, F; Thomas, C; Trignol, A; Van Beers, P, 2021)
" Recent and significant literature describing adverse events associated with energy drink use are reviewed."2.48Toxicity of energy drinks. ( Babu, KM; Ganetsky, M; Wolk, BJ, 2012)
"Caffeine is a plant-derived psychostimulant and a common additive found in a wide range of foods and pharmaceuticals."1.43Quantitative Proteomic Analysis of the Orbital Frontal Cortex in Rats Following Extended Exposure to Caffeine Reveals Extensive Changes to Protein Expression: Implications for Neurological Disease. ( Cornish, JL; Franklin, JL; Goodchild, AK; Haynes, PA; Homewood, J; Mirzaei, M; Wearne, TA, 2016)
"Caffeine is a receptor antagonist for adenosine that might interfere with the neuroprotective effect of adenosine in ischemic-hypoxic conditions."1.32Caffeine impairs short-term neurological outcome after concussive head injury in rats. ( Ahmad Khan, H; Al Deeb, S; Al Moutaery, K; Tariq, M, 2003)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Jee, HJ1
Lee, SG1
Bormate, KJ1
Jung, YS1
Erblang, M1
Sauvet, F1
Drogou, C1
Quiquempoix, M1
Van Beers, P1
Guillard, M1
Rabat, A1
Trignol, A1
Bourrilhon, C1
Erkel, MC1
Léger, D1
Thomas, C1
Gomez-Merino, D1
Chennaoui, M1
Franklin, JL1
Mirzaei, M1
Wearne, TA1
Homewood, J1
Goodchild, AK1
Haynes, PA1
Cornish, JL1
Ribeiro, JA1
Sebastião, AM1
Wolk, BJ1
Ganetsky, M1
Babu, KM1
Al Moutaery, K1
Al Deeb, S1
Ahmad Khan, H1
Tariq, M1
HABER, H1
MATTHIES, H1
ERDMANN, D1
Buhr, G1
Gunn, TR1
Metrakos, K1
Riley, P1
Willis, D1
Aranda, JV1
Panikarskiĭ, VG1
Tanaka, M1
Takeuchi, T1
Yagishita, S1
Inoue, T1
Walker, JS1
Yasuhara, M1
Levy, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Polymorphisms and Efficiency of Caffeine on Performances During Total Sleep Deprivation un Healthy Subject. Multicentric, Versus Placebo, Randomised, Cross Over, Double Blind Study[NCT03859882]52 participants (Actual)Interventional2018-09-02Completed
The Impact of Caffeine on Cognition in Schizophrenia[NCT02832401]24 participants (Actual)Interventional2016-09-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for caffeine and Nervous System Disorders

ArticleYear
Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human.
    Nutrients, 2020, Oct-09, Volume: 12, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Caffeine; Dose-Response Relationship, Drug;

2020
Caffeine and adenosine.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20 Suppl 1

    Topics: Adenosine; Animals; Caffeine; Cognition; Humans; Learning; Mental Disorders; Models, Biological; Ner

2010
Toxicity of energy drinks.
    Current opinion in pediatrics, 2012, Volume: 24, Issue:2

    Topics: Adolescent; Caffeine; Cardiovascular Diseases; Child; Drug Interactions; Energy Drinks; Ethanol; Hum

2012

Trials

1 trial available for caffeine and Nervous System Disorders

ArticleYear
Genetic Determinants of Neurobehavioral Responses to Caffeine Administration during Sleep Deprivation: A Randomized, Cross Over Study (NCT03859882).
    Genes, 2021, 04-10, Volume: 12, Issue:4

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Female;

2021

Other Studies

10 other studies available for caffeine and Nervous System Disorders

ArticleYear
Quantitative Proteomic Analysis of the Orbital Frontal Cortex in Rats Following Extended Exposure to Caffeine Reveals Extensive Changes to Protein Expression: Implications for Neurological Disease.
    Journal of proteome research, 2016, 05-06, Volume: 15, Issue:5

    Topics: Animals; Caffeine; Cell Communication; Cytoskeleton; Gene Expression Profiling; Gene Expression Regu

2016
Caffeine impairs short-term neurological outcome after concussive head injury in rats.
    Neurosurgery, 2003, Volume: 53, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain Concussion; Caffeine; Central Nervous System Stimulants; Disease

2003
[Thoughts and questions on neural therapy with impletol].
    Hippokrates, 1953, Feb-28, Volume: 24, Issue:4

    Topics: Caffeine; Drug Combinations; Humans; Nervous System Diseases; Procaine

1953
[Effect of caffeine on the conditioned reflex in rat & on experimental nervous system disorder].
    Die Pharmazie, 1957, Volume: 12, Issue:9

    Topics: Animals; Caffeine; Conditioning, Classical; Nervous System Diseases; Rats; Reflex

1957
[On the effect of caffeine on the peripheral circulation and its neural regulation].
    Arztliche Forschung, 1966, Feb-10, Volume: 20, Issue:2

    Topics: Arteriosclerosis; Blood Circulation; Caffeine; Coronary Disease; Humans; Hypertension; Nervous Syste

1966
Sequelae of caffeine treatment in preterm infants with apnea.
    The Journal of pediatrics, 1979, Volume: 94, Issue:1

    Topics: Apnea; Caffeine; Child Development; Female; Follow-Up Studies; Humans; Infant, Low Birth Weight; Inf

1979
[Problems in treatment of autonomic disorders accompanying hypertensive disease].
    Vrachebnoe delo, 1977, Issue:6

    Topics: Adult; Autonomic Nervous System; Benzimidazoles; Caffeine; Calcium; Female; Gluconates; Humans; Hype

1977
[A case of intoxication with thinner, Bond and Optalidon, showing various psychiatric symptoms and polyneuropathy].
    Rinsho shinkeigaku = Clinical neurology, 1975, Volume: 15, Issue:3

    Topics: Adult; Aminopyrine; Barbiturates; Caffeine; Drug Combinations; Humans; Male; Muscles; Nervous System

1975
Phenylpropanolamine potentiates caffeine neurotoxicity in rats.
    Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:12

    Topics: Animals; Appetite Depressants; Blood Proteins; Caffeine; Chromatography, High Pressure Liquid; Drug

1989
Caffeine as a potential risk factor for theophylline neurotoxicity.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:9

    Topics: Animals; Blood Proteins; Brain; Caffeine; Dialysis; Injections, Intravenous; Male; Nervous System Di

1988