caffeine has been researched along with Nerve Degeneration in 20 studies
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Caffeine, which is an antagonist of adenosine receptors, is the most widely consumed psychoactive drug in the world." | 5.43 | Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma. ( Agudo-Barriuso, M; Ambrósio, AF; Madeira, MH; Nadal-Nícolas, F; Ortin-Martinez, A; Santiago, AR; Vidal-Sanz, M, 2016) |
| "Treatment with ginsenosides attenuated KA-induced seizures and oxidative stress in the synaptosome, and reduced synaptic vesicles at the presynaptic terminals dose-dependently." | 3.75 | Ginsenosides attenuate kainic acid-induced synaptosomal oxidative stress via stimulation of adenosine A(2A) receptors in rat hippocampus. ( Chae, JS; Jeong, JH; Kim, AY; Kim, HC; Kim, SC; Kim, WK; Ko, KH; Koh, YH; Nah, SY; Shin, EJ; Yen, TP; Yoon, HJ, 2009) |
| "Co-treatment with caffeine significantly decreased these upregulations at all time points investigated, while caffeine without phenobarbital resulted in increased expression of TNFα, IL-1β, and IL-18, but not IFNγ at 6 h." | 1.46 | Caffeine Protects Against Anticonvulsant-Induced Neurotoxicity in the Developing Rat Brain. ( Bendix, I; Bührer, C; Endesfelder, S; Schiller, C; Sifringer, M; Weichelt, U, 2017) |
| "Caffeine, which is an antagonist of adenosine receptors, is the most widely consumed psychoactive drug in the world." | 1.43 | Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma. ( Agudo-Barriuso, M; Ambrósio, AF; Madeira, MH; Nadal-Nícolas, F; Ortin-Martinez, A; Santiago, AR; Vidal-Sanz, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 11 (55.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Endesfelder, S | 1 |
| Weichelt, U | 1 |
| Schiller, C | 1 |
| Sifringer, M | 1 |
| Bendix, I | 1 |
| Bührer, C | 1 |
| Zeidán-Chuliá, F | 1 |
| Gelain, DP | 1 |
| Kolling, EA | 1 |
| Rybarczyk-Filho, JL | 1 |
| Ambrosi, P | 1 |
| Terra, SR | 1 |
| Pires, AS | 1 |
| da Rocha, JB | 1 |
| Behr, GA | 1 |
| Moreira, JC | 1 |
| Stirling, DP | 1 |
| Cummins, K | 1 |
| Wayne Chen, SR | 1 |
| Stys, P | 1 |
| Moon, JH | 1 |
| Lee, JH | 1 |
| Park, JY | 1 |
| Kim, SW | 1 |
| Lee, YJ | 1 |
| Kang, SJ | 1 |
| Seol, JW | 1 |
| Ahn, DC | 1 |
| Park, SY | 1 |
| Frau, L | 2 |
| Costa, G | 1 |
| Porceddu, PF | 1 |
| Khairnar, A | 1 |
| Castelli, MP | 1 |
| Ennas, MG | 1 |
| Madeddu, C | 1 |
| Wardas, J | 1 |
| Morelli, M | 2 |
| Madeira, MH | 1 |
| Ortin-Martinez, A | 1 |
| Nadal-Nícolas, F | 1 |
| Ambrósio, AF | 1 |
| Vidal-Sanz, M | 1 |
| Agudo-Barriuso, M | 1 |
| Santiago, AR | 1 |
| Shin, EJ | 1 |
| Koh, YH | 1 |
| Kim, AY | 1 |
| Nah, SY | 1 |
| Jeong, JH | 1 |
| Chae, JS | 1 |
| Kim, SC | 1 |
| Yen, TP | 1 |
| Yoon, HJ | 1 |
| Kim, WK | 1 |
| Ko, KH | 1 |
| Kim, HC | 1 |
| Rigaud, M | 1 |
| Gemes, G | 1 |
| Weyker, PD | 1 |
| Cruikshank, JM | 1 |
| Kawano, T | 1 |
| Wu, HE | 1 |
| Hogan, QH | 1 |
| Duarte, JM | 1 |
| Carvalho, RA | 1 |
| Cunha, RA | 2 |
| Gruetter, R | 1 |
| Nobre, HV | 1 |
| Cunha, GM | 2 |
| de Vasconcelos, LM | 1 |
| Magalhães, HI | 1 |
| Oliveira Neto, RN | 1 |
| Maia, FD | 1 |
| de Moraes, MO | 1 |
| Leal, LK | 1 |
| Viana, GS | 1 |
| Canas, PM | 1 |
| Porciúncula, LO | 1 |
| Silva, CG | 1 |
| Machado, NJ | 1 |
| Oliveira, JM | 1 |
| Oliveira, CR | 1 |
| Zhao, X | 1 |
| Strong, R | 1 |
| Piriyawat, P | 1 |
| Palusinski, R | 1 |
| Grotta, JC | 1 |
| Aronowski, J | 1 |
| Kachroo, A | 1 |
| Irizarry, MC | 1 |
| Schwarzschild, MA | 1 |
| Sonsalla, PK | 1 |
| Wong, LY | 1 |
| Harris, SL | 1 |
| Richardson, JR | 1 |
| Khobahy, I | 1 |
| Li, W | 1 |
| Gadad, BS | 1 |
| German, DC | 1 |
| Simola, N | 1 |
| Kang, SH | 1 |
| Lee, YA | 1 |
| Won, SJ | 1 |
| Rhee, KH | 1 |
| Gwag, BJ | 1 |
| Joghataie, MT | 1 |
| Roghani, M | 1 |
| Negahdar, F | 1 |
| Hashemi, L | 1 |
| Dash, PK | 1 |
| Moore, AN | 1 |
| Moody, MR | 1 |
| Treadwell, R | 1 |
| Felix, JL | 1 |
| Clifton, GL | 1 |
| Casas, M | 1 |
| Prat, G | 1 |
| Robledo, P | 1 |
| Barbanoj, M | 1 |
| Kulisevsky, J | 1 |
| Jané, F | 1 |
| Albuquerque, EX | 1 |
| Warnick, JE | 1 |
| Sansone, FM | 1 |
| Onur, R | 1 |
20 other studies available for caffeine and Nerve Degeneration
| Article | Year |
|---|---|
Caffeine Protects Against Anticonvulsant-Induced Neurotoxicity in the Developing Rat Brain.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Caffeine; Cytokines; gamma-Aminobutyri | 2017 |
Major components of energy drinks (caffeine, taurine, and guarana) exert cytotoxic effects on human neuronal SH-SY5Y cells by decreasing reactive oxygen species production.
Topics: Antioxidants; Caffeine; Catalase; Cell Count; Cell Death; Cell Line, Tumor; Cell Shape; Cell Surviva | 2013 |
Axoplasmic reticulum Ca(2+) release causes secondary degeneration of spinal axons.
Topics: Animals; Axons; Bacterial Proteins; Boron Compounds; Caffeine; Calcium; Disease Models, Animal; Endo | 2014 |
Caffeine prevents human prion protein-mediated neurotoxicity through the induction of autophagy.
Topics: Autophagy; Caffeine; Cell Line, Tumor; Central Nervous System; Humans; Microtubule-Associated Protei | 2014 |
Influence of caffeine on 3,4-methylenedioxymethamphetamine-induced dopaminergic neuron degeneration and neuroinflammation is age-dependent.
Topics: Age Factors; Aging; Animals; Caffeine; Dopaminergic Neurons; Drug Synergism; Inflammation; Male; Mic | 2016 |
Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma.
Topics: Animals; Caffeine; Central Nervous System; Disease Models, Animal; Glaucoma; Humans; Inflammation; I | 2016 |
Ginsenosides attenuate kainic acid-induced synaptosomal oxidative stress via stimulation of adenosine A(2A) receptors in rat hippocampus.
Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Caffeine; Dose-Response Relationsh | 2009 |
Axotomy depletes intracellular calcium stores in primary sensory neurons.
Topics: Animals; Axons; Axotomy; Caffeine; Calcium; Calcium Signaling; Capsaicin; Cells, Cultured; Central N | 2009 |
Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Caffeine; Central Nervous System Stimulants; Chronic Disease; Diabetes Melli | 2009 |
Caffeine and CSC, adenosine A2A antagonists, offer neuroprotection against 6-OHDA-induced neurotoxicity in rat mesencephalic cells.
Topics: Adenosine A2 Receptor Agonists; Animals; Apoptosis; Caffeine; Cells, Cultured; Encephalitis; Female; | 2010 |
Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway.
Topics: Adenosine A2 Receptor Antagonists; Alzheimer Disease; Amyloid beta-Peptides; Animals; Caffeine; Cell | 2009 |
Caffeinol at the receptor level: anti-ischemic effect of N-methyl-D-aspartate receptor blockade is potentiated by caffeine.
Topics: Animals; Brain Ischemia; Caffeine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relati | 2010 |
Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration.
Topics: Animals; Caffeine; Cell Count; Chronic Disease; Disease Models, Animal; Dopamine; Drug Interactions; | 2010 |
Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's disease.
Topics: Animals; Caffeine; Cell Count; Disease Models, Animal; Disease Progression; Dopaminergic Neurons; Ma | 2012 |
Alteration in the progression of dopamine neuron degeneration: may caffeine offer new perspective?
Topics: Animals; Caffeine; Dopaminergic Neurons; Male; Nerve Degeneration; Parkinson Disease; Substantia Nig | 2012 |
Caffeine-induced neuronal death in neonatal rat brain and cortical cell cultures.
Topics: Animals; Animals, Newborn; Apoptosis; Caffeine; Caspase 3; Caspases; Cell Size; Cells, Cultured; Cer | 2002 |
Protective effect of caffeine against neurodegeneration in a model of Parkinson's disease in rat: behavioral and histochemical evidence.
Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Caffeine; Cell Count; Central Nervous | 2004 |
Post-trauma administration of caffeine plus ethanol reduces contusion volume and improves working memory in rats.
Topics: Animals; Brain Injuries; Caffeine; Cerebral Infarction; Disease Models, Animal; Drug Administration | 2004 |
Scopolamine prevents tolerance to the effects of caffeine on rotational behavior in 6-hydroxydopamine-denervated rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Toleran | 1999 |
Trophic functions of the neuron. 3. Mechanisms of neurotrophic interactions. The effects of vinblastine and colchicine on neural regulation of muscle.
Topics: Acetylcholine; Action Potentials; Adenosine Triphosphatases; Animals; Caffeine; Cell Membrane; Colch | 1974 |