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caffeine and Neoplasm Metastasis

caffeine has been researched along with Neoplasm Metastasis in 8 studies

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"In this study, we performed combination treatment of caffeine and valproic acid on osteosarcoma cell lines in vitro and in spontaneous and experimental lung metastasis mouse models of osteosarcoma."7.85Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice. ( Hayashi, K; Hoffman, RM; Igarashi, K; Kawaguchi, K; Kimura, H; Kiyuna, T; Miwa, S; Murakami, T; Tsuchiya, H; Yamamoto, N, 2017)
"The clinical and experimental findings demonstrate various anticancer properties of caffeine and caffeic acid against both ER(+) and ER(-) breast cancer that may sensitize tumor cells to tamoxifen and reduce breast cancer growth."7.81Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer. ( Holly, JM; Ingvar, C; Jernström, H; Markkula, A; Perks, CM; Rose, C; Rosendahl, AH; Simonsson, M; Zeng, L, 2015)
"In this study, we performed combination treatment of caffeine and valproic acid on osteosarcoma cell lines in vitro and in spontaneous and experimental lung metastasis mouse models of osteosarcoma."3.85Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice. ( Hayashi, K; Hoffman, RM; Igarashi, K; Kawaguchi, K; Kimura, H; Kiyuna, T; Miwa, S; Murakami, T; Tsuchiya, H; Yamamoto, N, 2017)
"The clinical and experimental findings demonstrate various anticancer properties of caffeine and caffeic acid against both ER(+) and ER(-) breast cancer that may sensitize tumor cells to tamoxifen and reduce breast cancer growth."3.81Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer. ( Holly, JM; Ingvar, C; Jernström, H; Markkula, A; Perks, CM; Rose, C; Rosendahl, AH; Simonsson, M; Zeng, L, 2015)
" We report here that inhibitors of both the cyclooxygenase and lipoxygenase pathways of arachidonic acid metabolism convert mouse melanoma and human fibrosarcoma cells to a non invasive state by reducing the production of MMP-2, an enzyme required for the degradation of basement membranes."3.69Identification of arachidonic acid pathways required for the invasive and metastatic activity of malignant tumor cells. ( Martin, GR; Reich, R, 1996)
"Lung cancer is recognized as a major cause of mortality worldwide owing to its metastatic activity."1.62Caffeine Induces G0/G1 Cell Cycle Arrest and Inhibits Migration through Integrin αv, β3, and FAK/Akt/c-Myc Signaling Pathway. ( Aksorn, N; Chanvorachote, P; Meisaprow, P; Sukprasansap, M; Vinayanuwattikun, C, 2021)
"(3)H-Adenosine metabolites were persistently retained after influx into the cell, predominantly as (3)H-adenosine triphosphate and (3)H-adenosine diphosphate."1.33In vitro evaluation of adenosine 5'-monophosphate as an imaging agent of tumor metabolism. ( Abraham, EH; Cho, SY; Engles, JM; Hilton, J; Polster, J; Wahl, RL, 2006)
"Tumor metastasis is a complex multistep process normally involving dysregulation of multiple signal transduction pathways."1.33Parallel analysis of transcript and translation profiles: identification of metastasis-related signal pathways differentially regulated by drug and genetic modifications. ( Chan, KC; Conrads, TP; Hunter, KW; Issaq, HJ; Lancaster, M; Lucas, DA; Lukes, L; Stephens, RM; Veenstra, TD; Yang, H; Yi, M; Yu, LR, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Meisaprow, P1
Aksorn, N1
Vinayanuwattikun, C1
Chanvorachote, P1
Sukprasansap, M1
Igarashi, K1
Kawaguchi, K1
Kiyuna, T1
Murakami, T1
Yamamoto, N1
Hayashi, K1
Kimura, H1
Miwa, S1
Tsuchiya, H1
Hoffman, RM1
Rosendahl, AH1
Perks, CM1
Zeng, L1
Markkula, A1
Simonsson, M1
Rose, C1
Ingvar, C1
Holly, JM1
Jernström, H1
Cho, SY1
Polster, J1
Engles, JM1
Hilton, J1
Abraham, EH1
Wahl, RL1
Yang, H1
Yu, LR1
Yi, M1
Lucas, DA1
Lukes, L1
Lancaster, M1
Chan, KC1
Issaq, HJ1
Stephens, RM1
Conrads, TP1
Veenstra, TD1
Hunter, KW1
Reich, R1
Martin, GR1
Chatterjee, SK1
Kim, U1
Harris, AL1

Reviews

1 review available for caffeine and Neoplasm Metastasis

ArticleYear
DNA repair and resistance to chemotherapy.
    Cancer surveys, 1985, Volume: 4, Issue:3

    Topics: Antineoplastic Agents; Caffeine; Cell Cycle; DNA Repair; Drug Resistance; Humans; Misonidazole; Muta

1985

Other Studies

7 other studies available for caffeine and Neoplasm Metastasis

ArticleYear
Caffeine Induces G0/G1 Cell Cycle Arrest and Inhibits Migration through Integrin αv, β3, and FAK/Akt/c-Myc Signaling Pathway.
    Molecules (Basel, Switzerland), 2021, Dec-17, Volume: 26, Issue:24

    Topics: Caffeine; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; G1 Phase Cell Cycle Checkpoints;

2021
Antimetastatic Efficacy of the Combination of Caffeine and Valproic Acid on an Orthotopic Human Osteosarcoma Cell Line Model in Nude Mice.
    Anticancer research, 2017, Volume: 37, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Cell Death; Cell

2017
Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Apr-15, Volume: 21, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Caffeic Acids; Caffeine; Cell C

2015
In vitro evaluation of adenosine 5'-monophosphate as an imaging agent of tumor metabolism.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Caffeine; Carbon Radioisotopes; Cell Line, Tumo

2006
Parallel analysis of transcript and translation profiles: identification of metastasis-related signal pathways differentially regulated by drug and genetic modifications.
    Journal of proteome research, 2006, Volume: 5, Issue:7

    Topics: Animals; Caffeine; Central Nervous System Stimulants; Crosses, Genetic; Gene Expression Regulation,

2006
Identification of arachidonic acid pathways required for the invasive and metastatic activity of malignant tumor cells.
    Prostaglandins, 1996, Volume: 51, Issue:1

    Topics: Animals; Arachidonic Acid; Caffeine; Collagen; Cyclooxygenase Inhibitors; Dinoprost; Drug Combinatio

1996
Biochemical properties of cyclic nucleotide phosphodiesterase in metastasizing and nonmetastasizing rat mammary carcinomas.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Calcium; Cobalt; Cyclic AMP; Cycl

1976