caffeine has been researched along with Necrotizing Enterocolitis in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Apnea of prematurity (AOP) is nearly universal among very preterm infants, but neither the apnea burden nor its clinical associations have been systematically studied in a large consecutive cohort." | 7.83 | Clinical associations of immature breathing in preterm infants: part 1-central apnea. ( Delos, J; Fairchild, K; Kattwinkel, J; Lake, D; Mohr, M; Moorman, JR; Paget-Brown, A; Tabacaru, C, 2016) |
| " All patients were evaluated for factors associated with the development of NEC including exposure to caffeine (dosing and duration), gestational age, birth weight, vasoactive medications and maternal illicit drug use." | 7.81 | Evaluation of caffeine and the development of necrotizing enterocolitis. ( Bookstaver, PB; Cox, C; Hashem, NG; Iskersky, V; Tebbs, J, 2015) |
| "The results of a case-control study of the potential role of caffeine citrate therapy in the development of necrotizing enterocolitis (NEC) are presented." | 7.79 | Association between caffeine citrate exposure and necrotizing enterocolitis in preterm infants. ( Brown, J; Fominaya, CE; Johnson, KK; Lakshminrusimha, S; Lampkin, SJ; Mathew, B; Turner, AM, 2013) |
| "Caffeine treatment is routinely used in premature infants to prevent development of apnea and bronchopulmonary dysplasia." | 7.30 | Effects of Different Onset Times of Early Caffeine Treatment on Mesenteric Tissue Oxygenation and Necrotizing Enterocolitis: A Prospective, Randomized Study. ( Cakir, SC; Cetinkaya, M; Koksal, N; Ozkan, H; Saglam, O, 2023) |
| "Caffeine was prescribed for apnea of prematurity and caffeine exposure was determined by chart review." | 5.51 | Caffeine exposure and acute kidney injury in premature infants with necrotizing enterocolitis and spontaneous intestinal perforation. ( Aviles-Otero, N; Carmody, JB; Green, G; Khalsa, DD; Kumar, R, 2019) |
| "Apnea of prematurity (AOP) is a common and pervasive problem in very low birth weight infants." | 4.98 | Caffeine: an evidence-based success story in VLBW pharmacotherapy. ( Dobson, NR; Hunt, CE, 2018) |
| "The use of caffeine citrate for treatment of apnea in very low birth weight infants showed short-term and long-term benefits." | 4.91 | Early Caffeine Use in Very Low Birth Weight Infants and Neonatal Outcomes: A Systematic Review and Meta-Analysis. ( Chung, S; Chung, SH; Kim, KS; Kim, SN; Lim, G; Park, HW, 2015) |
| "Apnea of prematurity (AOP) is nearly universal among very preterm infants, but neither the apnea burden nor its clinical associations have been systematically studied in a large consecutive cohort." | 3.83 | Clinical associations of immature breathing in preterm infants: part 1-central apnea. ( Delos, J; Fairchild, K; Kattwinkel, J; Lake, D; Mohr, M; Moorman, JR; Paget-Brown, A; Tabacaru, C, 2016) |
| " Extreme PB was identified in 76 infants and in 45% was temporally associated with clinical events including infection or necrotizing enterocolitis (NEC), immunizations, or caffeine discontinuation." | 3.83 | Clinical associations with immature breathing in preterm infants: part 2-periodic breathing. ( Delos, J; Fairchild, K; Kattwinkel, J; Lake, D; Mohr, M; Moorman, JR; Patel, M; Sinkin, RA, 2016) |
| " All patients were evaluated for factors associated with the development of NEC including exposure to caffeine (dosing and duration), gestational age, birth weight, vasoactive medications and maternal illicit drug use." | 3.81 | Evaluation of caffeine and the development of necrotizing enterocolitis. ( Bookstaver, PB; Cox, C; Hashem, NG; Iskersky, V; Tebbs, J, 2015) |
| "The results of a case-control study of the potential role of caffeine citrate therapy in the development of necrotizing enterocolitis (NEC) are presented." | 3.79 | Association between caffeine citrate exposure and necrotizing enterocolitis in preterm infants. ( Brown, J; Fominaya, CE; Johnson, KK; Lakshminrusimha, S; Lampkin, SJ; Mathew, B; Turner, AM, 2013) |
| "Caffeine treatment is routinely used in premature infants to prevent development of apnea and bronchopulmonary dysplasia." | 3.30 | Effects of Different Onset Times of Early Caffeine Treatment on Mesenteric Tissue Oxygenation and Necrotizing Enterocolitis: A Prospective, Randomized Study. ( Cakir, SC; Cetinkaya, M; Koksal, N; Ozkan, H; Saglam, O, 2023) |
| "Caffeine was prescribed for apnea of prematurity and caffeine exposure was determined by chart review." | 1.51 | Caffeine exposure and acute kidney injury in premature infants with necrotizing enterocolitis and spontaneous intestinal perforation. ( Aviles-Otero, N; Carmody, JB; Green, G; Khalsa, DD; Kumar, R, 2019) |
| "Caffeine citrate was used in extremely premature infants at younger gestation, at higher doses, and for longer durations than recommended on the drug label." | 1.51 | Dosing and Safety of Off-label Use of Caffeine Citrate in Premature Infants. ( Bendel-Stenzel, E; Chhabra, R; Harper, B; Ku, L; Laughon, M; Moya, F; Payne, EH; Puia-Dumitrescu, M; Smith, PB; Soriano, A; Wade, KC; Zhao, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Ozkan, H | 1 |
| Cetinkaya, M | 1 |
| Cakir, SC | 1 |
| Saglam, O | 1 |
| Koksal, N | 1 |
| Dobson, NR | 1 |
| Hunt, CE | 1 |
| Aviles-Otero, N | 1 |
| Kumar, R | 1 |
| Khalsa, DD | 1 |
| Green, G | 1 |
| Carmody, JB | 1 |
| Puia-Dumitrescu, M | 1 |
| Smith, PB | 1 |
| Zhao, J | 1 |
| Soriano, A | 1 |
| Payne, EH | 1 |
| Harper, B | 1 |
| Bendel-Stenzel, E | 1 |
| Moya, F | 1 |
| Chhabra, R | 1 |
| Ku, L | 1 |
| Laughon, M | 1 |
| Wade, KC | 1 |
| Lampkin, SJ | 1 |
| Turner, AM | 1 |
| Lakshminrusimha, S | 1 |
| Mathew, B | 1 |
| Brown, J | 1 |
| Fominaya, CE | 1 |
| Johnson, KK | 1 |
| Park, HW | 1 |
| Lim, G | 1 |
| Chung, SH | 1 |
| Chung, S | 1 |
| Kim, KS | 1 |
| Kim, SN | 1 |
| Cox, C | 1 |
| Hashem, NG | 1 |
| Tebbs, J | 1 |
| Bookstaver, PB | 1 |
| Iskersky, V | 1 |
| Fairchild, K | 2 |
| Mohr, M | 2 |
| Paget-Brown, A | 1 |
| Tabacaru, C | 1 |
| Lake, D | 2 |
| Delos, J | 2 |
| Moorman, JR | 2 |
| Kattwinkel, J | 2 |
| Patel, M | 1 |
| Sinkin, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics (PK) and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia[NCT05295784] | Phase 1 | 18 participants (Anticipated) | Interventional | 2024-06-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for caffeine and Necrotizing Enterocolitis
| Article | Year |
|---|---|
Caffeine: an evidence-based success story in VLBW pharmacotherapy.
Topics: Apnea; Caffeine; Central Nervous System Stimulants; Ductus Arteriosus, Patent; Enterocolitis, Necrot | 2018 |
Early Caffeine Use in Very Low Birth Weight Infants and Neonatal Outcomes: A Systematic Review and Meta-Analysis.
Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Citrates; Enterocolitis, Necrotizing; Humans; Infant; I | 2015 |
1 trial available for caffeine and Necrotizing Enterocolitis
| Article | Year |
|---|---|
Effects of Different Onset Times of Early Caffeine Treatment on Mesenteric Tissue Oxygenation and Necrotizing Enterocolitis: A Prospective, Randomized Study.
Topics: Birth Weight; Caffeine; Enterocolitis, Necrotizing; Female; Fetal Diseases; Humans; Infant; Infant, | 2023 |
6 other studies available for caffeine and Necrotizing Enterocolitis
| Article | Year |
|---|---|
Caffeine exposure and acute kidney injury in premature infants with necrotizing enterocolitis and spontaneous intestinal perforation.
Topics: Acute Kidney Injury; Age Factors; Caffeine; Enterocolitis, Necrotizing; Female; Gestational Age; Hum | 2019 |
Dosing and Safety of Off-label Use of Caffeine Citrate in Premature Infants.
Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Cerebral Hemorrhage; Citrates; Ductus Arteriosus, Paten | 2019 |
Association between caffeine citrate exposure and necrotizing enterocolitis in preterm infants.
Topics: Caffeine; Case-Control Studies; Central Nervous System Stimulants; Citrates; Comorbidity; Confoundin | 2013 |
Evaluation of caffeine and the development of necrotizing enterocolitis.
Topics: Birth Weight; Caffeine; Central Nervous System Stimulants; Enterocolitis, Necrotizing; Female; Gesta | 2015 |
Clinical associations of immature breathing in preterm infants: part 1-central apnea.
Topics: Algorithms; Apnea; Caffeine; Cohort Studies; Electrocardiography; Enterocolitis, Necrotizing; Female | 2016 |
Clinical associations with immature breathing in preterm infants: part 2-periodic breathing.
Topics: Caffeine; Cohort Studies; Electric Impedance; Enterocolitis, Necrotizing; Female; Gestational Age; H | 2016 |