caffeine has been researched along with Nausea in 32 studies
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to explore the relationships between nausea and vomiting in pregnancy and (a) fetal growth restriction; and (b) maternal caffeine metabolism and fetal growth restriction." | 7.79 | Does nausea and vomiting of pregnancy play a role in the association found between maternal caffeine intake and fetal growth restriction? ( Alwan, N; Boylan, SM; Cade, JE; Cooke, MS; Dolby, VA; Greenwood, DC; Hay, AW; Kirk, SF; Konje, JC; Potdar, N; Shires, S; Simpson, NA; Taub, N; Thomas, JD; Walker, JJ; White, KL; Wild, CP, 2013) |
| "Evidence for a harmful effect of caffeine intake on risk of miscarriage (spontaneous abortion) is inconsistent and nausea during pregnancy has been claimed to explain any association seen." | 7.72 | The effect of caffeine consumption and nausea on the risk of miscarriage. ( Doyle, P; Giannelli, M; Hermon, C; Pelerin, M; Roman, E, 2003) |
| "Signals of early pregnancy included an aversion to coffee in addition to nausea and vomiting, which resulted in decreased caffeine consumption." | 7.72 | Changes in caffeine consumption as a signal of pregnancy. ( Lawson, CC; LeMasters, GK; Wilson, KA, 2004) |
| " We analyzed data on 607 cases and 1,284 controls to evaluate the potential association between caffeine consumption during the first trimester of pregnancy and spontaneous abortion." | 7.68 | Caffeine consumption during pregnancy and spontaneous abortion. ( Eskenazi, B; Fenster, L; Swan, SH; Windham, GC, 1991) |
| "Ingestion of a combination of 5 mg x kg(-1) caffeine (C), and 1 mg x kg(-1) ephedrine (E) was reported to have an ergogenic effect on high intensity aerobic exercise performance, but 25% of the subjects experienced vomiting and nausea while engaging in hard exercise after the treatment." | 5.09 | Reducing the dose of combined caffeine and ephedrine preserves the ergogenic effect. ( Bell, DG; Jacobs, I; McLellan, TM; Zamecnik, J, 2000) |
| " Models accounted for women's age, BMI, employment, marital status, income, education, race, parity, prior losses, exercise and time-varying nausea/vomiting, caffeine, alcohol and smoking." | 4.12 | Prospectively assessed perceived stress associated with early pregnancy losses among women with history of pregnancy loss. ( Hinkle, SN; Kim, K; Mumford, SL; Plowden, TC; Purdue-Smithe, A; Schisterman, EF; Schliep, KC; Silver, RM; Sjaarda, LA; Stanford, JB, 2022) |
| "The aim of this study was to explore the relationships between nausea and vomiting in pregnancy and (a) fetal growth restriction; and (b) maternal caffeine metabolism and fetal growth restriction." | 3.79 | Does nausea and vomiting of pregnancy play a role in the association found between maternal caffeine intake and fetal growth restriction? ( Alwan, N; Boylan, SM; Cade, JE; Cooke, MS; Dolby, VA; Greenwood, DC; Hay, AW; Kirk, SF; Konje, JC; Potdar, N; Shires, S; Simpson, NA; Taub, N; Thomas, JD; Walker, JJ; White, KL; Wild, CP, 2013) |
| "Evidence for a harmful effect of caffeine intake on risk of miscarriage (spontaneous abortion) is inconsistent and nausea during pregnancy has been claimed to explain any association seen." | 3.72 | The effect of caffeine consumption and nausea on the risk of miscarriage. ( Doyle, P; Giannelli, M; Hermon, C; Pelerin, M; Roman, E, 2003) |
| "Signals of early pregnancy included an aversion to coffee in addition to nausea and vomiting, which resulted in decreased caffeine consumption." | 3.72 | Changes in caffeine consumption as a signal of pregnancy. ( Lawson, CC; LeMasters, GK; Wilson, KA, 2004) |
| " We analyzed data on 607 cases and 1,284 controls to evaluate the potential association between caffeine consumption during the first trimester of pregnancy and spontaneous abortion." | 3.68 | Caffeine consumption during pregnancy and spontaneous abortion. ( Eskenazi, B; Fenster, L; Swan, SH; Windham, GC, 1991) |
| "Treatment with almotriptan was associated with a significantly greater proportion of patients achieving 2-h pain free (20." | 2.73 | Crossover, double-blind clinical trial comparing almotriptan and ergotamine plus caffeine for acute migraine therapy. ( Galván, J; Heras, J; Láinez, MJ; Vila, C, 2007) |
| "Both caffeine and orthostasis have known cardiovascular effects." | 2.71 | The effect of caffeine on the cardiovascular responses to head-up tilt. ( Berry, NM; Newman, DG; Rickards, CA, 2003) |
| "Most people who experience migraine use OTC medications to treat their symptoms, but no head-to-head clinical trials comparing these agents with prescription migraine therapies have been published." | 2.71 | Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial. ( Baggish, J; Battikha, JP; Elkind, AH; Gallagher, RM; Goldstein, J; Hoffman, H; Saper, JR; Silberstein, SD; Smith, TR, 2005) |
| " The global incidence of adverse events was 45% higher with EC, though not significant (32 vs." | 2.69 | Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks. ( Geraud, G; Gómez, JP; Henry, P; Joffroy, A; Lainez, JM; Le Jeunne, C; Liaño, H; Pradalier, A; Titus i Albareda, F, 1999) |
| "Sumatriptan was significantly more effective than Cafergot at reducing the intensity of headache from severe or moderate to mild or none; 66% (145/220) of those treated with sumatriptan improved in this way by 2 h, compared with 48% (118/246) of those treated with Cafergot (p less than 0." | 2.67 | A randomized, double-blind comparison of sumatriptan and Cafergot in the acute treatment of migraine. The Multinational Oral Sumatriptan and Cafergot Comparative Study Group. ( , 1991) |
| "An analysis of calls to three poison centers for powdered caffeine found that exposures were uncommon, but did result in toxicity, and highlighted that the lack of clear dosing instructions on product packaging may place patients at risk of inadvertent overdose." | 1.43 | A Retrospective Study of Clinical Effects of Powdered Caffeine Exposures Reported to Three US Poison Control Centers. ( Beauchamp, GA; Crouch, BI; Hendrickson, RG; Horowitz, BZ; Johnson, AR; Valento, M, 2016) |
| "Effects of binge drinking on GI symptoms were strongest when comparing between individuals (rather than within individuals)." | 1.39 | Relationship between patterns of alcohol consumption and gastrointestinal symptoms among patients with irritable bowel syndrome. ( Cain, KC; Eugenio, MD; Heitkemper, MM; Jarrett, ME; Reding, KW, 2013) |
| "Migraine is one of the most common disorders seen in paediatric neurological practice." | 1.26 | Migraine and migraine equivalents in children. ( Brown, JK, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.50) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 12 (37.50) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Schliep, KC | 1 |
| Hinkle, SN | 1 |
| Kim, K | 1 |
| Sjaarda, LA | 1 |
| Silver, RM | 1 |
| Stanford, JB | 1 |
| Purdue-Smithe, A | 1 |
| Plowden, TC | 1 |
| Schisterman, EF | 1 |
| Mumford, SL | 1 |
| Wilson, PB | 1 |
| Beauchamp, GA | 1 |
| Johnson, AR | 1 |
| Crouch, BI | 1 |
| Valento, M | 1 |
| Horowitz, BZ | 1 |
| Hendrickson, RG | 1 |
| Boylan, SM | 1 |
| Greenwood, DC | 1 |
| Alwan, N | 1 |
| Cooke, MS | 1 |
| Dolby, VA | 1 |
| Hay, AW | 1 |
| Kirk, SF | 1 |
| Konje, JC | 1 |
| Potdar, N | 1 |
| Shires, S | 1 |
| Simpson, NA | 1 |
| Taub, N | 1 |
| Thomas, JD | 1 |
| Walker, JJ | 1 |
| White, KL | 1 |
| Wild, CP | 1 |
| Cade, JE | 1 |
| Reding, KW | 1 |
| Cain, KC | 1 |
| Jarrett, ME | 1 |
| Eugenio, MD | 1 |
| Heitkemper, MM | 1 |
| Iglesias-Lepine, ML | 1 |
| Epelde, F | 1 |
| Espinosa, J | 1 |
| Mariñosa, M | 1 |
| Lawson, CC | 2 |
| LeMasters, GK | 2 |
| Levin, LS | 1 |
| Liu, JH | 1 |
| Berry, NM | 1 |
| Rickards, CA | 1 |
| Newman, DG | 1 |
| Giannelli, M | 1 |
| Doyle, P | 1 |
| Roman, E | 1 |
| Pelerin, M | 1 |
| Hermon, C | 1 |
| Wilson, KA | 1 |
| Jessen, A | 1 |
| Buemann, B | 1 |
| Toubro, S | 1 |
| Skovgaard, IM | 1 |
| Astrup, A | 1 |
| Goldstein, J | 2 |
| Silberstein, SD | 1 |
| Saper, JR | 1 |
| Elkind, AH | 1 |
| Smith, TR | 1 |
| Gallagher, RM | 1 |
| Battikha, JP | 2 |
| Hoffman, H | 1 |
| Baggish, J | 1 |
| George, L | 1 |
| Granath, F | 2 |
| Johansson, AL | 1 |
| Annerén, G | 2 |
| Cnattingius, S | 2 |
| Láinez, MJ | 1 |
| Galván, J | 1 |
| Heras, J | 1 |
| Vila, C | 1 |
| Beine, S | 1 |
| Verwied, SC | 1 |
| Lührmann, PM | 1 |
| Kolasa, KM | 1 |
| Weismiller, DG | 1 |
| Le Jeunne, C | 1 |
| Gómez, JP | 1 |
| Pradalier, A | 1 |
| Titus i Albareda, F | 1 |
| Joffroy, A | 1 |
| Liaño, H | 1 |
| Henry, P | 1 |
| Lainez, JM | 1 |
| Geraud, G | 1 |
| Biederman, GB | 1 |
| Davey, VA | 1 |
| Hoffman, HD | 1 |
| Armellino, JJ | 1 |
| Hamelsky, SW | 1 |
| Couch, J | 1 |
| Blumenthal, H | 1 |
| Lipton, RB | 1 |
| Bell, DG | 1 |
| Jacobs, I | 1 |
| McLellan, TM | 1 |
| Zamecnik, J | 1 |
| Signorello, LB | 1 |
| Clausson, B | 1 |
| Ekbom, A | 1 |
| Ljunger, E | 1 |
| Blot, WJ | 1 |
| McLaughlin, JK | 1 |
| Petersson, G | 1 |
| Rane, A | 1 |
| Wen, W | 1 |
| Shu, XO | 1 |
| Jacobs, DR | 1 |
| Brown, JE | 1 |
| Furneaux, EC | 1 |
| Langley-Evans, AJ | 1 |
| Langley-Evans, SC | 1 |
| Brown, JK | 1 |
| Saxena, VK | 1 |
| De Deyn, PP | 1 |
| Fenster, L | 2 |
| Windham, GC | 2 |
| Swan, SH | 2 |
| Eskenazi, B | 2 |
| Stein, Z | 1 |
| Susser, M | 1 |
| Smits, P | 1 |
| Schouten, J | 1 |
| Thien, T | 1 |
| Weintraub, SJ | 1 |
| Naulty, JS | 1 |
| Grawitz, PB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Aspirin in Gestation and Reproduction: A Multi-center, Controlled, Double-blind Randomized Trial.[NCT00467363] | 1,228 participants (Actual) | Interventional | 2007-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Partial or complete abruption (ie, premature separation of the placenta) (NCT00467363)
Timeframe: until delivery
| Intervention | participants (Number) |
|---|---|
| Aspirin | 7 |
| Placebo | 5 |
(NCT00467363)
Timeframe: 8-weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 374 |
| Placebo | 346 |
Implantation failures (NCT00467363)
Timeframe: 8 weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 28 |
| Placebo | 27 |
(NCT00467363)
Timeframe: within 6 weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 3 |
| Placebo | 3 |
(NCT00467363)
Timeframe: until 40 weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 4 |
| Placebo | 6 |
(NCT00467363)
Timeframe: within 8-weeks of gestation
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 394 |
| Placebo | 363 |
Live birth was obtained prospectively by maternal report and abstraction from medical records by trained staff . (NCT00467363)
Timeframe: after delivery
| Intervention | livebirths (Number) |
|---|---|
| Aspirin | 309 |
| Placebo | 286 |
(NCT00467363)
Timeframe: 8 weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 0 |
| Placebo | 0 |
(NCT00467363)
Timeframe: until delivery
| Intervention | participants (Number) |
|---|---|
| Aspirin | 32 |
| Placebo | 30 |
Includes preembryonic and embryonic losses (exclusive of implantation failures) (NCT00467363)
Timeframe: less than 10-weeks
| Intervention | pregnancy (Number) |
|---|---|
| Aspirin | 56 |
| Placebo | 53 |
(NCT00467363)
Timeframe: until delivery
| Intervention | infants (Number) |
|---|---|
| Aspirin | 22 |
| Placebo | 31 |
birthweight (NCT00467363)
Timeframe: until delivery
| Intervention | grams (Mean) |
|---|---|
| Aspirin | 3327 |
| Placebo | 3315 |
(NCT00467363)
Timeframe: 40 weeks
| Intervention | participants (Number) |
|---|---|
| Aspirin | 2 |
| Placebo | 2 |
3 reviews available for caffeine and Nausea
| Article | Year |
|---|---|
Nutrition during pregnancy.
Topics: Caffeine; Constipation; Female; Humans; Lactose Intolerance; Nausea; Nutrition Assessment; Nutrition | 1997 |
Nausea and vomiting of pregnancy: endocrine basis and contribution to pregnancy outcome.
Topics: Abortion, Spontaneous; Alcohol Drinking; Caffeine; Chorionic Gonadotropin; Congenital Abnormalities; | 2001 |
Ergotamine: its use in the treatment of migraine and its complications.
Topics: Autonomic Nervous System Diseases; Caffeine; Cardiovascular Diseases; Contraindications; Drug Admini | 1992 |
10 trials available for caffeine and Nausea
| Article | Year |
|---|---|
The effect of caffeine on the cardiovascular responses to head-up tilt.
Topics: Adult; Blood Pressure; Caffeine; Cardiovascular Physiological Phenomena; Dizziness; Female; Heart Ra | 2003 |
The appetite-suppressant effect of nicotine is enhanced by caffeine.
Topics: Adolescent; Adult; Appetite; Appetite Depressants; Caffeine; Chewing Gum; Double-Blind Method; Drug | 2005 |
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non- | 2005 |
Crossover, double-blind clinical trial comparing almotriptan and ergotamine plus caffeine for acute migraine therapy.
Topics: Acute Disease; Adult; Caffeine; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; | 2007 |
Coffee consumption and total body water homeostasis as measured by fluid balance and bioelectrical impedance analysis.
Topics: Adult; Blood Circulation; Body Water; Body Weight; Caffeine; Coffee; Diuresis; Female; Headache; Hom | 1997 |
Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Th | 1999 |
Treatment of severe, disabling migraine attacks in an over-the-counter population of migraine sufferers: results from three randomized, placebo-controlled studies of the combination of acetaminophen, aspirin, and caffeine.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Caffeine; Double-Blind Method; D | 1999 |
Reducing the dose of combined caffeine and ephedrine preserves the ergogenic effect.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Drug Combinations; Ephedrin | 2000 |
A randomized, double-blind comparison of sumatriptan and Cafergot in the acute treatment of migraine. The Multinational Oral Sumatriptan and Cafergot Comparative Study Group.
Topics: Administration, Oral; Adult; Aged; Caffeine; Double-Blind Method; Drug Combinations; Electrocardiogr | 1991 |
Cardiovascular effects of two xanthines and the relation to adenosine antagonism.
Topics: Adenosine; Adult; Aldosterone; Blood Pressure; Caffeine; Double-Blind Method; Epinephrine; Female; H | 1989 |
19 other studies available for caffeine and Nausea
| Article | Year |
|---|---|
Prospectively assessed perceived stress associated with early pregnancy losses among women with history of pregnancy loss.
Topics: Abortion, Spontaneous; Biomarkers; Caffeine; Child; Female; Humans; Nausea; Pregnancy; Stress, Psych | 2022 |
Dietary and non-dietary correlates of gastrointestinal distress during the cycle and run of a triathlon.
Topics: Abdominal Pain; Adult; Caffeine; Diet; Dietary Carbohydrates; Energy Intake; Female; Flatulence; Gas | 2016 |
A Retrospective Study of Clinical Effects of Powdered Caffeine Exposures Reported to Three US Poison Control Centers.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Child; Combined Modality Therapy; Dietary Supple | 2016 |
Does nausea and vomiting of pregnancy play a role in the association found between maternal caffeine intake and fetal growth restriction?
Topics: Adolescent; Adult; Caffeine; Female; Fetal Development; Fetal Growth Retardation; Gestational Age; H | 2013 |
Relationship between patterns of alcohol consumption and gastrointestinal symptoms among patients with irritable bowel syndrome.
Topics: Abdominal Pain; Adult; Alcohol Drinking; Binge Drinking; Caffeine; Case-Control Studies; Coffee; Con | 2013 |
[Consumption of energy drinks with alcohol, hazardous mixture].
Topics: Adolescent; Alcoholic Beverages; Caffeine; Catecholamines; Dose-Response Relationship, Drug; Drug Sy | 2013 |
Pregnancy hormone metabolite patterns, pregnancy symptoms, and coffee consumption.
Topics: Adult; Caffeine; Chorionic Gonadotropin; Coffee; Estrone; Female; Humans; Nausea; Pregnancy; Pregnan | 2002 |
The effect of caffeine consumption and nausea on the risk of miscarriage.
Topics: Abortion, Spontaneous; Adult; Beverages; Caffeine; Case-Control Studies; Coffee; Dose-Response Relat | 2003 |
Changes in caffeine consumption as a signal of pregnancy.
Topics: Adolescent; Adult; Asian People; Black or African American; Caffeine; Chorionic Gonadotropin; Coffee | 2004 |
Environmental tobacco smoke and risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Biomarkers; Caffeine; Case-Control Studies; Chromosome Aberrations; Co | 2006 |
Alleviating nausea and emesis by Pavlovian conditioning.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Conditioning, Classical; Dose-Response Relatio | 1999 |
Caffeine intake and the risk of first-trimester spontaneous abortion.
Topics: Abortion, Spontaneous; Adolescent; Adult; Caffeine; Case-Control Studies; Chromosome Aberrations; Ch | 2000 |
The associations of maternal caffeine consumption and nausea with spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Caffeine; Female; Humans; Minnesota; Nausea; Odds Ratio; Pregnancy; Pr | 2001 |
Migraine and migraine equivalents in children.
Topics: Caffeine; Capillary Permeability; Cerebrovascular Circulation; Child; Diagnosis, Differential; Epile | 1977 |
Miscarriage, caffeine, and the epiphenomena of pregnancy: the causal model.
Topics: Abortion, Spontaneous; Caffeine; Female; Humans; Nausea; Pregnancy; Pregnancy Complications | 1991 |
Miscarriage, caffeine, and the epiphenomena of pregnancy: the causal model.
Topics: Abortion, Spontaneous; Beverages; Caffeine; Female; Humans; Nausea; Pregnancy; Pregnancy Complicatio | 1991 |
Caffeine consumption during pregnancy and spontaneous abortion.
Topics: Abortion, Spontaneous; Adult; Beverages; Caffeine; California; Case-Control Studies; Demography; Fem | 1991 |
Acute abstinence syndrome after epidural injection of butorphanol.
Topics: Adult; Anesthesia, Epidural; Aspirin; Blood Pressure; Butorphanol; Caffeine; Cesarean Section; Codei | 1985 |
[Prophylaxis and therapy of the mountain sickness, puna].
Topics: Altitude; Caffeine; Ergotamine; Headache; Humans; Hypoxia; Nausea; Oxygen Inhalation Therapy; Physic | 1971 |