caffeine has been researched along with Multiple Sclerosis in 11 studies
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The association between alcohol and caffeine intakes and risk of multiple sclerosis (MS) is unclear; no prospective studies have examined this relationship." | 7.79 | Caffeine and alcohol intakes have no association with risk of multiple sclerosis. ( Ascherio, A; Massa, J; Munger, KL; O'Reilly, EJ, 2013) |
| "Caffeine treatment augmented A1AR expression on microglia, with ensuing reduction of EAE severity, which was further enhanced by concomitant treatment with the A1AR agonist, adenosine amine congener." | 5.32 | A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. ( Henry, S; Noorbakhsh, F; Power, C; Schnermann, J; Tsutsui, S; Warren, K; Winston, BW; Yong, VW, 2004) |
| "The association between alcohol and caffeine intakes and risk of multiple sclerosis (MS) is unclear; no prospective studies have examined this relationship." | 3.79 | Caffeine and alcohol intakes have no association with risk of multiple sclerosis. ( Ascherio, A; Massa, J; Munger, KL; O'Reilly, EJ, 2013) |
| "Fluid intake and lower urinary tract symptoms were assessed by the questionnaire based voiding diary and the American Urological Association Symptom Score, respectively." | 1.56 | Fluid Intake and Urinary Symptoms in Patients with Multiple Sclerosis. ( Cheung, A; Gross, MD; Kim, JM; Melville, PM; Tam, J; Weissbart, SJ, 2020) |
| "Caffeine treatment augmented A1AR expression on microglia, with ensuing reduction of EAE severity, which was further enhanced by concomitant treatment with the A1AR agonist, adenosine amine congener." | 1.32 | A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. ( Henry, S; Noorbakhsh, F; Power, C; Schnermann, J; Tsutsui, S; Warren, K; Winston, BW; Yong, VW, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 4 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, K | 1 |
| Fallon, SJ | 1 |
| Davis, T | 1 |
| Ankrett, S | 1 |
| Munro, G | 1 |
| Christopher, G | 1 |
| Coulthard, E | 1 |
| Herden, L | 1 |
| Weissert, R | 1 |
| Tam, J | 1 |
| Gross, MD | 1 |
| Cheung, A | 1 |
| Melville, PM | 1 |
| Kim, JM | 1 |
| Weissbart, SJ | 1 |
| Janitschke, D | 1 |
| Lauer, AA | 1 |
| Bachmann, CM | 1 |
| Grimm, HS | 1 |
| Hartmann, T | 1 |
| Grimm, MOW | 1 |
| Evans, E | 1 |
| Piccio, L | 1 |
| Cross, AH | 1 |
| Chen, GQ | 1 |
| Chen, YY | 1 |
| Wang, XS | 1 |
| Wu, SZ | 1 |
| Yang, HM | 1 |
| Xu, HQ | 1 |
| He, JC | 1 |
| Wang, XT | 1 |
| Chen, JF | 1 |
| Zheng, RY | 1 |
| Massa, J | 1 |
| O'Reilly, EJ | 1 |
| Munger, KL | 1 |
| Ascherio, A | 1 |
| FINKE, H | 1 |
| POPEK, K | 1 |
| Tsutsui, S | 1 |
| Schnermann, J | 1 |
| Noorbakhsh, F | 1 |
| Henry, S | 1 |
| Yong, VW | 1 |
| Winston, BW | 1 |
| Warren, K | 1 |
| Power, C | 1 |
| Maas, AG | 1 |
| Hogenhuis, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adjuvant Effects of Vitamin A and Vitamin D Supplementation on Treatment of Children With ADHD:A Randomized, Double Blind, Placebo-controlled, Multicentric Trial.[NCT04284059] | Phase 4 | 504 participants (Anticipated) | Interventional | 2021-02-25 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for caffeine and Multiple Sclerosis
| Article | Year |
|---|---|
Methylxanthines and Neurodegenerative Diseases: An Update.
Topics: Alzheimer Disease; Animals; Caffeine; Coffee; Humans; Multiple Sclerosis; Neurodegenerative Diseases | 2021 |
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
Topics: Acetylcarnitine; Animals; Ascorbic Acid; Biotin; Caffeine; Creatine; Curcumin; Dietary Supplements; | 2018 |
9 other studies available for caffeine and Multiple Sclerosis
| Article | Year |
|---|---|
Preliminary evidence that caffeine improves attention in multiple sclerosis.
Topics: Attention; Attentional Blink; Caffeine; Cognition; Humans; Multiple Sclerosis; Reaction Time | 2022 |
The Effect of Coffee and Caffeine Consumption on Patients with Multiple Sclerosis-Related Fatigue.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Caffeine; Coffee; Disability Evaluation; Drinking Behavi | 2020 |
Fluid Intake and Urinary Symptoms in Patients with Multiple Sclerosis.
Topics: Adult; Beverages; Caffeine; Cross-Sectional Studies; Drinking; Female; Humans; Lower Urinary Tract S | 2020 |
Chronic caffeine treatment attenuates experimental autoimmune encephalomyelitis induced by guinea pig spinal cord homogenates in Wistar rats.
Topics: Animals; Caffeine; Central Nervous System; Cytokines; Disease Models, Animal; Dose-Response Relation | 2010 |
Caffeine and alcohol intakes have no association with risk of multiple sclerosis.
Topics: Alcohol Drinking; Caffeine; Diet; Female; Humans; Multiple Sclerosis; Risk Factors; Surveys and Ques | 2013 |
[The treatment of spastic paralysis with intratendonous impletol injections].
Topics: Caffeine; Drug Combinations; Humans; Injections; Multiple Sclerosis; Muscle Spasticity; Paralysis; P | 1954 |
THE STUDY OF CHANGES IN THE SO-CALLED SUCCESSIVE CONTRAST IN NEUROLOGY.
Topics: Afterimage; Amphetamine; Arteriosclerosis; Brain Concussion; Brain Injuries; Brain Neoplasms; Bromid | 1964 |
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Caffeine; Disease Models, Animal; Disease Progre | 2004 |
Multiple sclerosis and possible relationship to cocoa: a hypothesis.
Topics: Animals; Cacao; Caffeine; England; Food Hypersensitivity; Humans; Israel; Multiple Sclerosis; Norway | 1987 |