caffeine has been researched along with Metabolic Syndrome in 30 studies
Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This systematic review aimed to study caffeine's effect on the cardiometabolic markers of the metabolic syndrome and to evaluate caffeine's application as a potential therapeutic agent in rat models." | 9.41 | Systematic review of the effect of caffeine therapy effect on cardiometabolic markers in rat models of the metabolic syndrome. ( Al Ansari, AM; Alabbasi, AMA; Alhadi, IA; AlSaleh, AFF, 2023) |
| "Prenatal caffeine exposure (PCE) alters the hypothalamic-pituitary-adrenocortical (HPA) axis-associated neuroendocrine metabolic programming and induces an increased susceptibility to metabolic syndrome (MS) in intrauterine growth retardation (IUGR) offspring rats." | 7.81 | Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet. ( Chen, L; Guo, Y; He, Z; Li, J; Luo, H; Ma, L; Magdalou, J; Wang, H; Wu, Y; Zhang, L, 2015) |
| "We tested the hypothesis that long-term caffeine intake prevents the development of insulin resistance and hypertension in two pathological animal models: the high-fat (HF) and the high-sucrose (HSu) diet rat." | 7.78 | Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats. ( Conde, SV; Gonzalez, C; Guarino, MP; Monteiro, EC; Mota Carmo, M; Nunes da Silva, T, 2012) |
| "Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements." | 6.53 | Caffeine and cardiovascular diseases: critical review of current research. ( Hayes, A; Klimas, J; Kobyliak, N; Kruzliak, P; Kubatka, P; La Rocca, G; Loftus, H; Novak, J; Pohanka, M; Qaradakhi, T; Smith, RM; Soucek, M; Uehara, Y; Zagatina, A; Zulli, A, 2016) |
| "This systematic review aimed to study caffeine's effect on the cardiometabolic markers of the metabolic syndrome and to evaluate caffeine's application as a potential therapeutic agent in rat models." | 5.41 | Systematic review of the effect of caffeine therapy effect on cardiometabolic markers in rat models of the metabolic syndrome. ( Al Ansari, AM; Alabbasi, AMA; Alhadi, IA; AlSaleh, AFF, 2023) |
| "The treatment with caffeine in the rats fed the high-carbohydrate, high-fat diet decreased body fat and systolic blood pressure, improved glucose tolerance and insulin sensitivity, and attenuated cardiovascular and hepatic abnormalities, although the plasma lipid concentrations were further increased." | 5.38 | Caffeine attenuates metabolic syndrome in diet-induced obese rats. ( Brown, L; Kauter, K; Panchal, SK; Ward, LC; Wong, WY, 2012) |
| " We used a combination of the keywords "coffee", "caffeine", "tea", "non-alcoholic fatty liver disease", "non-alcoholic steatohepatitis", "metabolic syndrome"." | 4.93 | Coffee and tea consumption in relation with non-alcoholic fatty liver and metabolic syndrome: A systematic review and meta-analysis of observational studies. ( Del Rio, D; Godos, J; Grosso, G; Marventano, S; Mistretta, A; Pluchinotta, F; Salomone, F, 2016) |
| "Prenatal caffeine exposure (PCE) alters the hypothalamic-pituitary-adrenocortical (HPA) axis-associated neuroendocrine metabolic programming and induces an increased susceptibility to metabolic syndrome (MS) in intrauterine growth retardation (IUGR) offspring rats." | 3.81 | Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet. ( Chen, L; Guo, Y; He, Z; Li, J; Luo, H; Ma, L; Magdalou, J; Wang, H; Wu, Y; Zhang, L, 2015) |
| "We tested the hypothesis that long-term caffeine intake prevents the development of insulin resistance and hypertension in two pathological animal models: the high-fat (HF) and the high-sucrose (HSu) diet rat." | 3.78 | Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats. ( Conde, SV; Gonzalez, C; Guarino, MP; Monteiro, EC; Mota Carmo, M; Nunes da Silva, T, 2012) |
| "Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements." | 2.53 | Caffeine and cardiovascular diseases: critical review of current research. ( Hayes, A; Klimas, J; Kobyliak, N; Kruzliak, P; Kubatka, P; La Rocca, G; Loftus, H; Novak, J; Pohanka, M; Qaradakhi, T; Smith, RM; Soucek, M; Uehara, Y; Zagatina, A; Zulli, A, 2016) |
| "Current drug treatments for obesity produce small and usually unsustainable decreases in body weight with the risk of major adverse effects." | 2.52 | Functional foods as potential therapeutic options for metabolic syndrome. ( Brown, L; Panchal, SK; Poudyal, H, 2015) |
| "Ursolic acid (1) was identified as the responsible for the activity of maté and guayusa extracts in the activation of TGR5, a nuclear receptor of relevance for the prevention and management of diabetes and metabolic syndrome because of its involvement in the regulation of energy expenditure and insulin sensitivity." | 1.51 | Bioactive triterpenoids from the caffeine-rich plants guayusa and maté. ( Appendino, G; Chianese, G; Collado, JA; Golin-Pacheco, SD; Munoz, E; Pollastro, F; Taglialatela-Scafati, O, 2019) |
| "Metabolic syndrome is one of the most important health issues worldwide." | 1.46 | Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice. ( Baba, H; Morimoto, Y; Ogawa, H; Takahashi, T; Tsunematsu, T; Tsuneyama, K; Uehara, H; Watanabe, S, 2017) |
| "The treatment with caffeine in the rats fed the high-carbohydrate, high-fat diet decreased body fat and systolic blood pressure, improved glucose tolerance and insulin sensitivity, and attenuated cardiovascular and hepatic abnormalities, although the plasma lipid concentrations were further increased." | 1.38 | Caffeine attenuates metabolic syndrome in diet-induced obese rats. ( Brown, L; Kauter, K; Panchal, SK; Ward, LC; Wong, WY, 2012) |
| "Metabolic syndrome was defined as the presence of > or = 3 of the following: waist circumference > or = 35 inches (women) or > or = 40 inches (men); fasting blood glucose > or = 100 mg/dL; serum triglycerides > or = 150 mg/dL; blood pressure > or = 135/85 mm Hg; and high-density lipoprotein cholesterol < 40 mg/dL (men) or < 50 mg/dL (women)." | 1.34 | Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. ( D'Agostino, RB; Dhingra, R; Fox, CS; Gaziano, JM; Jacques, PF; Meigs, JB; Sullivan, L; Vasan, RS; Wang, TJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 23 (76.67) | 24.3611 |
| 2020's | 3 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, S | 1 |
| Han, Y | 1 |
| Zhao, H | 1 |
| Han, X | 1 |
| Yin, Y | 1 |
| Wu, J | 1 |
| Zhang, Y | 1 |
| Zeng, X | 1 |
| Alhadi, IA | 1 |
| Al Ansari, AM | 1 |
| AlSaleh, AFF | 1 |
| Alabbasi, AMA | 1 |
| Henn, M | 1 |
| Babio, N | 1 |
| Romaguera, D | 1 |
| Vázquez-Ruiz, Z | 1 |
| Konieczna, J | 1 |
| Vioque, J | 1 |
| Torres-Collado, L | 1 |
| Razquin, C | 1 |
| Buil-Cosiales, P | 1 |
| Fitó, M | 1 |
| Schröder, H | 1 |
| Hu, FB | 1 |
| Abete, I | 1 |
| Zulet, MÁ | 1 |
| Fernández-Villa, T | 1 |
| Martín, V | 1 |
| Estruch, R | 1 |
| Vidal, J | 1 |
| Paz-Graniel, I | 1 |
| Martínez, JA | 1 |
| Salas-Salvadó, J | 1 |
| Martínez-González, MA | 1 |
| Ruiz-Canela, M | 1 |
| Watanabe, S | 2 |
| Takahashi, T | 1 |
| Ogawa, H | 2 |
| Uehara, H | 1 |
| Tsunematsu, T | 2 |
| Baba, H | 1 |
| Morimoto, Y | 2 |
| Tsuneyama, K | 2 |
| Baspinar, B | 1 |
| Eskici, G | 1 |
| Ozcelik, AO | 1 |
| Pei, LG | 1 |
| Yuan, C | 1 |
| Guo, YT | 1 |
| Kou, H | 1 |
| Xia, LP | 1 |
| Zhang, L | 2 |
| Yan, YE | 1 |
| Xu, D | 1 |
| Wang, H | 2 |
| Gao, X | 1 |
| Xie, Q | 1 |
| Kong, P | 1 |
| Liu, L | 1 |
| Sun, S | 1 |
| Xiong, B | 1 |
| Huang, B | 1 |
| Yan, L | 1 |
| Sheng, J | 1 |
| Xiang, H | 1 |
| Roshan, H | 1 |
| Nikpayam, O | 1 |
| Sedaghat, M | 1 |
| Sohrab, G | 1 |
| Kawada, T | 1 |
| Nishitsuji, K | 1 |
| Xiao, J | 1 |
| Nagatomo, R | 1 |
| Umemoto, H | 1 |
| Akatsu, H | 1 |
| Inoue, K | 1 |
| Chianese, G | 1 |
| Golin-Pacheco, SD | 1 |
| Taglialatela-Scafati, O | 1 |
| Collado, JA | 1 |
| Munoz, E | 1 |
| Appendino, G | 1 |
| Pollastro, F | 1 |
| Grosso, G | 2 |
| Marventano, S | 2 |
| Galvano, F | 1 |
| Pajak, A | 1 |
| Mistretta, A | 2 |
| Bajerska, J | 1 |
| Mildner-Szkudlarz, S | 1 |
| Walkowiak, J | 1 |
| Li, J | 1 |
| Luo, H | 1 |
| Wu, Y | 1 |
| He, Z | 1 |
| Guo, Y | 1 |
| Ma, L | 1 |
| Magdalou, J | 1 |
| Chen, L | 1 |
| Brown, L | 3 |
| Poudyal, H | 2 |
| Panchal, SK | 3 |
| Platt, DE | 1 |
| Ghassibe-Sabbagh, M | 1 |
| Salameh, P | 1 |
| Salloum, AK | 1 |
| Haber, M | 1 |
| Mouzaya, F | 1 |
| Gauguier, D | 1 |
| Al-Sarraj, Y | 1 |
| El-Shanti, H | 1 |
| Zalloua, PA | 1 |
| Abchee, AB | 1 |
| Zulli, A | 1 |
| Smith, RM | 1 |
| Kubatka, P | 1 |
| Novak, J | 1 |
| Uehara, Y | 1 |
| Loftus, H | 1 |
| Qaradakhi, T | 1 |
| Pohanka, M | 1 |
| Kobyliak, N | 1 |
| Zagatina, A | 1 |
| Klimas, J | 1 |
| Hayes, A | 1 |
| La Rocca, G | 1 |
| Soucek, M | 1 |
| Kruzliak, P | 1 |
| Salomone, F | 1 |
| Godos, J | 1 |
| Pluchinotta, F | 1 |
| Del Rio, D | 1 |
| Sarriá, B | 1 |
| Martínez-López, S | 1 |
| Sierra-Cinos, JL | 1 |
| García-Diz, L | 1 |
| Mateos, R | 1 |
| Bravo-Clemente, L | 1 |
| Balk, L | 1 |
| Hoekstra, T | 1 |
| Twisk, J | 1 |
| Wang, J | 1 |
| Chang, T | 1 |
| Høstmark, AT | 1 |
| Conde, SV | 1 |
| Nunes da Silva, T | 1 |
| Gonzalez, C | 1 |
| Mota Carmo, M | 1 |
| Monteiro, EC | 1 |
| Guarino, MP | 1 |
| Waanders, J | 1 |
| Wong, WY | 1 |
| Kauter, K | 1 |
| Ward, LC | 1 |
| Ihm, SH | 1 |
| Jang, SW | 1 |
| Kim, OR | 1 |
| Chang, K | 1 |
| Oak, MH | 1 |
| Lee, JO | 1 |
| Lim, DY | 1 |
| Kim, JH | 1 |
| Kromann, CB | 1 |
| Nielsen, CT | 1 |
| Zimmerman, E | 1 |
| Wylie-Rosett, J | 1 |
| Hino, A | 1 |
| Adachi, H | 1 |
| Enomoto, M | 1 |
| Furuki, K | 1 |
| Shigetoh, Y | 1 |
| Ohtsuka, M | 1 |
| Kumagae, S | 1 |
| Hirai, Y | 1 |
| Jalaldin, A | 1 |
| Satoh, A | 1 |
| Imaizumi, T | 1 |
| Dhingra, R | 1 |
| Sullivan, L | 1 |
| Jacques, PF | 1 |
| Wang, TJ | 1 |
| Fox, CS | 1 |
| Meigs, JB | 1 |
| D'Agostino, RB | 1 |
| Gaziano, JM | 1 |
| Vasan, RS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Green Coffee Supplementation on Inflammatory Biomarkers in Obese Patients With Metabolic Syndrome[NCT05688917] | 160 participants (Actual) | Interventional | 2020-09-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for caffeine and Metabolic Syndrome
| Article | Year |
|---|---|
Systematic review of the effect of caffeine therapy effect on cardiometabolic markers in rat models of the metabolic syndrome.
Topics: Animals; Caffeine; Hypertension; Insulin Resistance; Metabolic Syndrome; Obesity; Rats | 2023 |
How coffee affects metabolic syndrome and its components.
Topics: Caffeine; Coffee; Humans; Metabolic Syndrome | 2017 |
Functional foods as potential therapeutic options for metabolic syndrome.
Topics: Animals; Anthocyanins; Antioxidants; Caffeine; Dietary Fiber; Disease Models, Animal; Ellagic Acid; | 2015 |
Caffeine and cardiovascular diseases: critical review of current research.
Topics: Animals; Blood Vessels; Caffeine; Cardiovascular Diseases; Clinical Studies as Topic; Coffee; Diseas | 2016 |
Coffee and tea consumption in relation with non-alcoholic fatty liver and metabolic syndrome: A systematic review and meta-analysis of observational studies.
Topics: Caffeine; Coffee; Diet; Humans; Liver Cirrhosis; MEDLINE; Metabolic Syndrome; Non-alcoholic Fatty Li | 2016 |
Nutrition therapy for hypertension.
Topics: Alcohol Drinking; Behavior Therapy; Caffeine; Diet; Exercise; Humans; Hypertension; Life Style; Meta | 2003 |
3 trials available for caffeine and Metabolic Syndrome
| Article | Year |
|---|---|
Effects of green coffee extract supplementation on anthropometric indices, glycaemic control, blood pressure, lipid profile, insulin resistance and appetite in patients with the metabolic syndrome: a randomised clinical trial.
Topics: Adult; Aged; Appetite; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Caffeine; Coffea | 2018 |
Effects of rye bread enriched with green tea extract on weight maintenance and the characteristics of metabolic syndrome following weight loss: a pilot study.
Topics: Blood Pressure; Body Mass Index; Body Weight Maintenance; Bread; Caffeine; Camellia sinensis; Catech | 2015 |
Regularly consuming a green/roasted coffee blend reduces the risk of metabolic syndrome.
Topics: Adipokines; Adolescent; Adult; Blood Glucose; Blood Pressure; Body Composition; Caffeine; Coffea; Co | 2018 |
21 other studies available for caffeine and Metabolic Syndrome
| Article | Year |
|---|---|
Association between Coffee Consumption, Caffeine Intake, and Metabolic Syndrome Severity in Patients with Self-Reported Rheumatoid Arthritis: National Health and Nutrition Examination Survey 2003-2018.
Topics: Arthritis, Rheumatoid; Caffeine; Coffee; Humans; Metabolic Syndrome; Nutrition Surveys; Risk Factors | 2022 |
Increase from low to moderate, but not high, caffeinated coffee consumption is associated with favorable changes in body fat.
Topics: Adipose Tissue; Caffeine; Coffee; Female; Humans; Male; Metabolic Syndrome; Obesity; Prospective Stu | 2023 |
Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice.
Topics: Aging; Animals; Caffeine; Coffee; Diabetes Mellitus, Type 2; Hyperlipidemias; Insulin-Secreting Cell | 2017 |
Prenatal caffeine exposure induced high susceptibility to metabolic syndrome in adult female offspring rats and its underlying mechanisms.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Blood Glucose; Caffeine; Central Nervous Syste | 2017 |
Polyphenol- and Caffeine-Rich Postfermented Pu-erh Tea Improves Diet-Induced Metabolic Syndrome by Remodeling Intestinal Homeostasis in Mice.
Topics: Animals; Caffeine; Cell Line; Cell Line, Tumor; Diet, High-Fat; Endotoxemia; Gastrointestinal Microb | 2018 |
Decaffeinated green coffee bean extract and the components of the metabolic syndrome.
Topics: Beverages; Body Mass Index; Body Weight; Caffeine; Coffee; Cross-Over Studies; Cross-Sectional Studi | 2018 |
Effect of coffee or coffee components on gut microbiome and short-chain fatty acids in a mouse model of metabolic syndrome.
Topics: Animals; Caffeine; Chlorogenic Acid; Coffee; Disease Models, Animal; Dysbiosis; Fatty Acids, Volatil | 2018 |
Bioactive triterpenoids from the caffeine-rich plants guayusa and maté.
Topics: Caffeine; Diabetes Mellitus; Ilex guayusa; Ilex paraguariensis; Insulin Resistance; Metabolic Syndro | 2019 |
Factors associated with metabolic syndrome in a mediterranean population: role of caffeinated beverages.
Topics: Adult; Aged; Beverages; Caffeine; Coffee; Cross-Sectional Studies; Female; Humans; Italy; Male; Meta | 2014 |
Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet.
Topics: Adrenocorticotropic Hormone; Age Factors; Analysis of Variance; Animal Nutritional Physiological Phe | 2015 |
Caffeine Impact on Metabolic Syndrome Components Is Modulated by a CYP1A2 Variant.
Topics: Aged; Alleles; Body Mass Index; Caffeine; Cholesterol, HDL; Cholesterol, LDL; Coffee; Cohort Studies | 2016 |
Relationship between long-term coffee consumption and components of the metabolic syndrome: the Amsterdam Growth and Health Longitudinal Study.
Topics: Caffeine; Cardiovascular Diseases; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Linear Models; | 2009 |
Methylglyoxal content in drinking coffee as a cytotoxic factor.
Topics: Animals; Apoptosis; Caffeine; Cell Proliferation; Chromatography, High Pressure Liquid; Coffee; Cyto | 2010 |
The Oslo health study: soft drink intake is associated with the metabolic syndrome.
Topics: Adult; Caffeine; Carbonated Beverages; Cross-Sectional Studies; Dietary Sucrose; Feeding Behavior; F | 2010 |
Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats.
Topics: Adiposity; Adrenergic Antagonists; Animals; Body Weight; Caffeine; Carbazoles; Carvedilol; Catechola | 2012 |
Coffee extract attenuates changes in cardiovascular and hepatic structure and function without decreasing obesity in high-carbohydrate, high-fat diet-fed male rats.
Topics: Animals; Anti-Obesity Agents; Caffeine; Coffee; Diet, High-Fat; Dietary Sucrose; Diterpenes; Fatty L | 2012 |
Caffeine attenuates metabolic syndrome in diet-induced obese rats.
Topics: Adipose Tissue; Animals; Blood Pressure; Caffeine; Cardiovascular System; Diet, High-Fat; Dietary Ca | 2012 |
Decaffeinated green tea extract improves hypertension and insulin resistance in a rat model of metabolic syndrome.
Topics: Animals; Antihypertensive Agents; Antioxidants; Aorta, Thoracic; Blood Glucose; Blood Pressure; Caff | 2012 |
A case of cola dependency in a woman with recurrent depression.
Topics: Adult; Caffeine; Carbonated Beverages; Chronic Disease; Cola; Depressive Disorder, Major; Female; Hu | 2012 |
Habitual coffee but not green tea consumption is inversely associated with metabolic syndrome: an epidemiological study in a general Japanese population.
Topics: Aged; Caffeine; Coffee; Feeding Behavior; Female; Humans; Japan; Male; Metabolic Syndrome; Middle Ag | 2007 |
Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community.
Topics: Aged; Caffeine; Carbonated Beverages; Cholesterol, LDL; Cohort Studies; Cross-Sectional Studies; Dia | 2007 |