caffeine has been researched along with Liver Dysfunction in 68 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigates the involvement of liver dysfunction in the modulation of paracetamol pharmacokinetic profile in genotype-4 HCV patients treated with either paracetamol alone (Para) or in combination with caffeine (Para-Caf)." | 9.22 | Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus. ( Abdel-Aziz, AA; Ashour, AA; Atta, R; Botros, SS; El-Lakkany, NM; Hendawy, AS; Mansour, AM; Seif El-Din, SH, 2016) |
| "The patients with liver cirrhosis were classified according to the Child--Pugh scoring system." | 6.68 | [Diagnostic value of the study of caffeine elimination in chronic liver diseases]. ( Bariska, J; Darnót, G; Nemesánszky, E, 1995) |
| "Caffeine clearance was also measured and the results were correlated with the galactose elimination capacity and with antipyrine clearance." | 5.27 | Caffeine intake, fasting plasma caffeine and caffeine clearance in patients with liver diseases. ( Bianchi, GP; Checchia, GA; Grossi, G; Lolli, R; Marchesini, G; Pisi, E; Zoli, M, 1988) |
| "This study investigates the involvement of liver dysfunction in the modulation of paracetamol pharmacokinetic profile in genotype-4 HCV patients treated with either paracetamol alone (Para) or in combination with caffeine (Para-Caf)." | 5.22 | Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus. ( Abdel-Aziz, AA; Ashour, AA; Atta, R; Botros, SS; El-Lakkany, NM; Hendawy, AS; Mansour, AM; Seif El-Din, SH, 2016) |
| "Caffeine elimination was studied in 419 patients with cirrhotic and noncirrhotic liver disease of different etiology (hepatitis B virus infection n = 79; hepatitis NANB virus infection n = 74; ethanol-induced liver damage n = 143; primary biliary cirrhosis I-IV n = 63; cryptogenic liver cirrhosis n = 60) following oral administration of 366 mg caffeine." | 3.68 | Caffeine elimination in cirrhotic and non-cirrhotic liver disease of different etiology. ( Brachtel, D; Gallenkamp, H; Hofstetter, G; Joeres, R; Klinker, H; Richter, E; Zilly, W, 1993) |
| "In 56 patients with various liver diseases and in 15 healthy controls fasting serum concentrations of caffeine (HPLC method) and total endogenous bile acids (enzymatic-spectrophotometric assay) were determined." | 3.68 | [Comparison of the value of serum caffeine and bile acid concentrations as indicators of liver injury]. ( Habior, A; Ostrowski, J; Trzeciak, L; Wojciechowski, K, 1990) |
| "The elimination of caffeine from the plasma and the elimination of metamizol-metabolites in urine were determined in 37 patients with different liver diseases." | 3.67 | [Effect of various liver diseases on the activity of 2 subtypes of cytochrome P-450]. ( Balogh, A; Reinhardt, M; Simon, HJ; Splinter, FK; Traeger, A, 1987) |
| "Fasting plasma caffeine concentration and various parameters of caffeine elimination from plasma obtained after a standardized oral dose of 140 mg caffeine have been compared in nine patients with liver cirrhosis, eight patients with non-cirrhotic liver disease and ten healthy volunteers with regard to their ability to discriminate between the different groups." | 3.67 | Caffeine elimination: a test of liver function. ( Kleber, G; Paumgartner, G; Stellaard, F; Wang, T, 1985) |
| "Mephenytoin metabolism was significantly decreased in both patients with mild liver disease (Child-Pugh score of 5/6) (-63% [95% confidence interval (CI), -86% to -40%]; P = ." | 2.72 | Liver disease selectively modulates cytochrome P450--mediated metabolism. ( Branch, RA; Chaves-Gnecco, D; Frye, RF; Matzke, GR; Rabinovitz, M; Shaikh, OS; Zgheib, NK, 2006) |
| "Years of alcohol abuse and of smoking, alcohol and coffee intake, and smoking rate were estimated in a semistructured interview, and Fagerström Tolerance Questionnaire was completed by inpatients." | 2.69 | Joint influence of alcohol, tobacco, and coffee on biological markers of heavy drinking in alcoholics. ( Aubin, HJ; Barrucand, D; Laureaux, C; Tilikete, S; Vallat, B; Vernier, F; Zerah, F, 1998) |
| "The caffeine metabolites were also measured in the urine of these subjects by high-performance liquid chromatography, and urinary molar ratios of 5-acetylamino-6-formylamino-3-methyluracil (AFMU), 1-methylxanthine (1X), 1-methyluric acid (1U), and 1,7-dimethyluric acid (17U) were employed to estimate the activities of CYP1A2, NAT, and XO." | 2.69 | Salivary clearance and urinary metabolic pattern of caffeine in healthy children and in pediatric patients with hepatocellular diseases. ( al-Humidan, A; al-Rawithi, S; el-Yazigi, A; Legayada, ES; Shabib, S; Yusuf, A, 1999) |
| "Repaglinide is a novel insulin secretagogue developed in response to the need for a fast-acting, oral prandial glucose regulator for the treatment of type 2 (non-insulin-dependent) diabetes mellitus." | 2.69 | Single-dose pharmacokinetics of repaglinide in subjects with chronic liver disease. ( Christensen, MS; Hatorp, V; Haug-Pihale, G; Walther, KH, 2000) |
| "The patients with liver cirrhosis were classified according to the Child--Pugh scoring system." | 2.68 | [Diagnostic value of the study of caffeine elimination in chronic liver diseases]. ( Bariska, J; Darnót, G; Nemesánszky, E, 1995) |
| "Caffeine elimination was studied in 73 patients admitted to an intensive care unit, 33 of whom had liver disease." | 2.68 | Caffeine test assessment for measuring liver function in critically ill patients. ( Calatayud, O; Ibáñez, P; Rodríguez, M; Sánchez-Alcaraz, A, 1995) |
| "Caffeine in hair was identified and measured by gas chromatography-mass spectrometry after digestion of the hair matrix with protease and extraction of the caffeine with chloroform." | 2.68 | The measurement of caffeine concentration in scalp hair as an indicator of liver function. ( Gotoh, S; Katoh, E; Mizuno, A; Nakashima, M; Uematsu, T, 1996) |
| "As liver diseases are a major health problem and especially the incidence of metabolic liver diseases like non-alcoholic fatty liver disease (NAFLD) is rising, the demand for non-invasive tests is growing to replace liver biopsy." | 2.50 | Critical appraisal of 13C breath tests for microsomal liver function: aminopyrine revisited. ( Bast, A; de Vries, H; Koek, GH; Nikkessen, S; Pijls, KE; Wodzig, WK, 2014) |
| "Pretreatment with caffeine, nicotinic acid or non-substituted pyrazinoic acid activated the LPS/D-GalN induced elevation of plasma IL-10 levels at 1 and 2 h, although there were no statistically significant differences in IL-10 levels between control and nicotinic acid or non-substituted pyrazinoic acid treated rats." | 1.35 | Protective effects of coffee-derived compounds on lipopolysaccharide/D-galactosamine induced acute liver injury in rats. ( Akashi, I; Hirano, T; Kagami, K; Oka, K, 2009) |
| "Volumes of total liver, hepatic cysts, hepatic parenchyma, and total kidney were measured by a validated computed tomography (CT) technique." | 1.30 | Postmenopausal estrogen therapy selectively stimulates hepatic enlargement in women with autosomal dominant polycystic kidney disease. ( Bronner, T; Everson, GT; McKinley, C; Russ, P; Scherzinger, A; Sherstha, R; Showalter, R, 1997) |
| "Caffeine was a competitive inhibitor of APAP bioactivation in microsomes from beta NF- and acetone-treated mice." | 1.29 | Interaction of caffeine with acetaminophen. 1. Correlation of the effect of caffeine on acetaminophen hepatotoxicity and acetaminophen bioactivation following treatment of mice with various cytochrome P450 inducing agents. ( Jaw, S; Jeffery, EH, 1993) |
| "This study attempted to compare the pharmacokinetic parameters of caffeine in patients with chronic liver disease and in normal subjects and to define the two sampling times which are suitable for determining caffeine clearance in these patients." | 1.29 | Caffeine clearance by two point analysis: a measure of liver function in chronic liver disease. ( Israsena, S; Komolmit, P; Thamaree, S; Tongnopnoua, P; Wittayalertpanya, S, 1996) |
| "Allopurinol and caffeine have been used to measure metabolite formation followed by renal elimination of both parent substance and metabolite." | 1.28 | Liver function assessment by drug metabolism. ( Barstow, L; Small, RE, 1990) |
| "With aminopyrine the decrease was abrupt but with caffeine biphasic, consistent with preferential isozyme depletion." | 1.28 | A model of cytochrome P-450-centered hepatic dysfunction in drug metabolism induced by cobalt-protoporphyrin administration. ( Halter, S; Hanew, T; Muhoberac, BB; Schenker, S, 1989) |
| "Caffeine clearance was also measured and the results were correlated with the galactose elimination capacity and with antipyrine clearance." | 1.27 | Caffeine intake, fasting plasma caffeine and caffeine clearance in patients with liver diseases. ( Bianchi, GP; Checchia, GA; Grossi, G; Lolli, R; Marchesini, G; Pisi, E; Zoli, M, 1988) |
| "Caffeine was extracted from diluted serum and saliva samples (10-500 microliter) by adsorption on a small Bond-Elut C18 cartridge and recovered by elution with methanol." | 1.27 | Rapid high-performance liquid chromatography assay for salivary and serum caffeine following an oral load. An indicator of liver function. ( Balistreri, WF; Klooster, MJ; Lim, CK; Setchell, KD; Welsh, MB, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (39.71) | 18.7374 |
| 1990's | 23 (33.82) | 18.2507 |
| 2000's | 10 (14.71) | 29.6817 |
| 2010's | 8 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernández, JR | 1 |
| Sweet, ES | 1 |
| Welsh, WJ | 1 |
| Firestein, BL | 1 |
| Nieber, K | 1 |
| Baldissera, MD | 2 |
| Souza, CF | 2 |
| Descovi, SN | 1 |
| Petrolli, TG | 1 |
| da Silva, AS | 2 |
| Baldisserotto, B | 2 |
| Abbad, LB | 1 |
| Verdi, CM | 1 |
| Santos, RC | 1 |
| Pijls, KE | 1 |
| de Vries, H | 1 |
| Nikkessen, S | 1 |
| Bast, A | 1 |
| Wodzig, WK | 1 |
| Koek, GH | 1 |
| Kober, H | 1 |
| Tatsch, E | 1 |
| Torbitz, VD | 1 |
| Cargnin, LP | 1 |
| Sangoi, MB | 1 |
| Bochi, GV | 1 |
| da Silva, AR | 1 |
| Barbisan, F | 1 |
| Ribeiro, EE | 1 |
| da Cruz, IB | 1 |
| Moresco, RN | 1 |
| El-Lakkany, NM | 1 |
| Hendawy, AS | 1 |
| Seif El-Din, SH | 1 |
| Ashour, AA | 1 |
| Atta, R | 1 |
| Abdel-Aziz, AA | 1 |
| Mansour, AM | 1 |
| Botros, SS | 1 |
| Akashi, I | 1 |
| Kagami, K | 1 |
| Hirano, T | 1 |
| Oka, K | 1 |
| Tarantino, G | 1 |
| Ohta, A | 1 |
| Sitkovsky, M | 1 |
| Centerholt, C | 1 |
| Ekblom, M | 1 |
| Odergren, T | 1 |
| Borgå, O | 1 |
| Popescu, G | 1 |
| Molz, KH | 1 |
| Couturier, A | 1 |
| Weil, A | 1 |
| SAPELKINA, LV | 1 |
| Park, GJ | 1 |
| Katelaris, PH | 1 |
| Jones, DB | 1 |
| Seow, F | 1 |
| Le Couteur, DG | 1 |
| Ngu, MC | 1 |
| Kukongviriyapan, V | 1 |
| Senggunprai, L | 1 |
| Prawan, A | 1 |
| Gaysornsiri, D | 1 |
| Kukongviriyapan, U | 1 |
| Aiemsa-Ard, J | 1 |
| Ruhl, CE | 1 |
| Everhart, JE | 2 |
| Frye, RF | 1 |
| Zgheib, NK | 1 |
| Matzke, GR | 1 |
| Chaves-Gnecco, D | 1 |
| Rabinovitz, M | 1 |
| Shaikh, OS | 1 |
| Branch, RA | 1 |
| Sakka, SG | 1 |
| Bukowskyj, M | 1 |
| Nakatsu, K | 1 |
| Munt, PW | 1 |
| Baker, AL | 1 |
| Kotake, AN | 1 |
| Schoeller, DA | 1 |
| Zysset, T | 1 |
| Wahlländer, A | 4 |
| Preisig, R | 4 |
| Renner, E | 3 |
| Wahländer, A | 1 |
| Huguenin, P | 1 |
| Wietholtz, H | 2 |
| Zilly, W | 3 |
| Caesar, U | 1 |
| Richter, E | 3 |
| Heusler, H | 1 |
| Brodie, MJ | 1 |
| Boobis, AR | 1 |
| Bulpitt, CJ | 1 |
| Davies, DS | 1 |
| Joeres, R | 2 |
| Brachtel, D | 1 |
| Gallenkamp, H | 1 |
| Hofstetter, G | 2 |
| Klinker, H | 2 |
| Baker, A | 1 |
| Girling, A | 1 |
| Worthington, D | 1 |
| Ballantine, N | 1 |
| Smith, S | 1 |
| Tarlow, M | 1 |
| Kelly, D | 1 |
| Darnót, G | 1 |
| Nemesánszky, E | 1 |
| Bariska, J | 1 |
| Schaad, HJ | 1 |
| Renner, EL | 1 |
| Arnaud, MJ | 1 |
| Calatayud, O | 1 |
| Rodríguez, M | 1 |
| Sánchez-Alcaraz, A | 1 |
| Ibáñez, P | 1 |
| Van Thiel, DH | 1 |
| Hassanein, T | 1 |
| Boothe, DM | 1 |
| Cullen, JM | 1 |
| Calvin, JA | 1 |
| Jenkins, WL | 1 |
| Brown, SA | 1 |
| Green, RA | 1 |
| Corrier, DE | 1 |
| Jaw, S | 1 |
| Jeffery, EH | 1 |
| Mizuno, A | 1 |
| Uematsu, T | 1 |
| Gotoh, S | 1 |
| Katoh, E | 1 |
| Nakashima, M | 1 |
| Wittayalertpanya, S | 1 |
| Israsena, S | 1 |
| Thamaree, S | 1 |
| Tongnopnoua, P | 1 |
| Komolmit, P | 1 |
| Sherstha, R | 1 |
| McKinley, C | 1 |
| Russ, P | 1 |
| Scherzinger, A | 1 |
| Bronner, T | 1 |
| Showalter, R | 1 |
| Everson, GT | 1 |
| Tanaka, E | 2 |
| Breimer, DD | 1 |
| Aubin, HJ | 1 |
| Laureaux, C | 1 |
| Zerah, F | 1 |
| Tilikete, S | 1 |
| Vernier, F | 1 |
| Vallat, B | 1 |
| Barrucand, D | 1 |
| el-Yazigi, A | 1 |
| Shabib, S | 1 |
| al-Rawithi, S | 1 |
| Yusuf, A | 1 |
| Legayada, ES | 1 |
| al-Humidan, A | 1 |
| Sugiyama, K | 1 |
| He, P | 1 |
| Wada, S | 1 |
| Saeki, S | 1 |
| Sharp, DS | 1 |
| Benowitz, NL | 1 |
| Hatorp, V | 1 |
| Walther, KH | 1 |
| Christensen, MS | 1 |
| Haug-Pihale, G | 1 |
| Studlar, M | 1 |
| Pichler, O | 1 |
| Zeller, W | 2 |
| Ishikawa, A | 1 |
| Yamamoto, Y | 1 |
| Uchida, E | 1 |
| Kobayashi, S | 1 |
| Yasuhara, H | 1 |
| Misawa, S | 1 |
| Kraul, H | 1 |
| Truckenbrodt, J | 1 |
| Sigusch, H | 1 |
| Hippius, M | 1 |
| Machnik, G | 1 |
| Hoffmann, A | 1 |
| McDonagh, JE | 1 |
| Nathan, VV | 1 |
| Bonavia, IC | 1 |
| Moyle, GR | 1 |
| Tanner, AR | 1 |
| Habior, A | 1 |
| Ostrowski, J | 1 |
| Trzeciak, L | 1 |
| Wojciechowski, K | 1 |
| Mohr, S | 1 |
| Paumgartner, G | 2 |
| Weiss, M | 1 |
| Barstow, L | 1 |
| Small, RE | 1 |
| Callery, MP | 1 |
| Ricordi, C | 1 |
| Scharp, DW | 1 |
| Kamei, T | 1 |
| Swanson, CJ | 1 |
| Lacy, PE | 1 |
| Flye, MW | 1 |
| Muhoberac, BB | 1 |
| Hanew, T | 1 |
| Halter, S | 1 |
| Schenker, S | 1 |
| Bosman, DK | 1 |
| de Haan, JG | 1 |
| Smit, J | 1 |
| Jorning, GG | 1 |
| Maas, MA | 1 |
| Chamuleau, RA | 1 |
| Lacroix, C | 1 |
| Nouveau, J | 1 |
| Laine, G | 1 |
| Guyonnaud, CD | 1 |
| Hubscher, P | 1 |
| Duwoos, H | 1 |
| Goulle, JP | 1 |
| Marchesini, G | 1 |
| Checchia, GA | 1 |
| Grossi, G | 1 |
| Lolli, R | 1 |
| Bianchi, GP | 1 |
| Zoli, M | 1 |
| Pisi, E | 1 |
| Setchell, KD | 1 |
| Welsh, MB | 1 |
| Klooster, MJ | 1 |
| Balistreri, WF | 1 |
| Lim, CK | 1 |
| Balogh, A | 1 |
| Simon, HJ | 1 |
| Reinhardt, M | 1 |
| Splinter, FK | 1 |
| Traeger, A | 1 |
| Huesler, H | 1 |
| Epping, J | 1 |
| Drost, D | 1 |
| Reuss, H | 1 |
| Kalow, W | 1 |
| Sato, C | 1 |
| Izumi, N | 1 |
| Nouchi, T | 1 |
| Hasumura, Y | 1 |
| Takeuchi, J | 1 |
| Karlaganis, G | 1 |
| Wang, T | 1 |
| Kleber, G | 1 |
| Stellaard, F | 1 |
| Heyden, S | 2 |
| Sturm, A | 1 |
| Scheja, HW | 1 |
| Puentes, F | 1 |
| Burgmann, W | 1 |
8 reviews available for caffeine and Liver Dysfunction
| Article | Year |
|---|---|
The Impact of Coffee on Health.
Topics: Animals; Caffeine; Cardiovascular System; Coffee; Diabetes Mellitus, Type 2; Humans; Inflammatory Bo | 2017 |
Critical appraisal of 13C breath tests for microsomal liver function: aminopyrine revisited.
Topics: Acetamides; Aminopyrine; Aryl Hydrocarbon Hydroxylases; Breath Tests; Caffeine; Carbon Isotopes; Cyt | 2014 |
Methylxanthines, inflammation, and cancer: fundamental mechanisms.
Topics: Acute Disease; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Coffee; Hepatitis; Humans; Live | 2011 |
Assessing liver function.
Topics: Aminopyrine; Caffeine; Critical Care; Humans; Liver; Liver Diseases; Liver Function Tests; Sulfobrom | 2007 |
Theophylline reassessed.
Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; | 1984 |
Clinical utility of breath tests for the assessment of hepatic function.
Topics: Aminopyrine; Breath Tests; Caffeine; Chemical and Drug Induced Liver Injury; Chronic Disease; Cytoch | 1983 |
Assessment of liver function: the current situation.
Topics: Caffeine; Cytochrome P-450 Enzyme System; Humans; Lidocaine; Liver; Liver Circulation; Liver Disease | 1995 |
In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease.
Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome | 1997 |
12 trials available for caffeine and Liver Dysfunction
| Article | Year |
|---|---|
A caffeine-supplemented diet modulates oxidative stress markers and prevents oxidative damage in the livers of Nile tilapia (Oreochromis niloticus) exposed to hypoxia.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Biomarkers; Caffeine; Catalase; Ce | 2019 |
Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus.
Topics: Acetaminophen; Adult; Aged; Analgesics; Arabs; Biological Availability; Caffeine; Female; Hepatitis | 2016 |
Pharmacokinetics and sedative effects in healthy subjects and subjects with impaired liver function after continuous infusion of clomethiazole.
Topics: Area Under Curve; Caffeine; Chlormethiazole; Dose-Response Relationship, Drug; Female; Half-Life; Hu | 2003 |
Salivary caffeine metabolic ratio in alcohol-dependent subjects.
Topics: Alcoholism; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrom | 2004 |
Liver disease selectively modulates cytochrome P450--mediated metabolism.
Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Caffeine; Case-Control Studie | 2006 |
[Diagnostic value of the study of caffeine elimination in chronic liver diseases].
Topics: Administration, Oral; Caffeine; Chronic Disease; Female; Gastrointestinal Transit; Hepatitis, Alcoho | 1995 |
Caffeine test assessment for measuring liver function in critically ill patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biotransformation; Caffeine; Female; Humans; Intensive C | 1995 |
The measurement of caffeine concentration in scalp hair as an indicator of liver function.
Topics: Adult; Caffeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Indicators and Reagents | 1996 |
Joint influence of alcohol, tobacco, and coffee on biological markers of heavy drinking in alcoholics.
Topics: Adult; Alcohol Drinking; Alcoholism; Biomarkers; Caffeine; Coffee; Cotinine; Cross-Sectional Studies | 1998 |
Salivary clearance and urinary metabolic pattern of caffeine in healthy children and in pediatric patients with hepatocellular diseases.
Topics: Adolescent; Aspartate Aminotransferases; Bilirubin; Blood Proteins; Caffeine; Central Nervous System | 1999 |
Single-dose pharmacokinetics of repaglinide in subjects with chronic liver disease.
Topics: Adult; Blood Glucose; Blood Proteins; Caffeine; Carbamates; Chronic Disease; Humans; Hypoglycemic Ag | 2000 |
[Effect of coffee on fat metabolism].
Topics: Caffeine; Coffee; Fatty Acids, Nonesterified; Humans; Lipid Metabolism; Lipids; Liver; Liver Disease | 1968 |
48 other studies available for caffeine and Liver Dysfunction
| Article | Year |
|---|---|
Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine.
Topics: Binding Sites; Cognition Disorders; Energy Metabolism; Guanine; Guanine Deaminase; Humans; Kinetics; | 2010 |
Dietary supplementation with caffeine increases survival rate, reduces microbial load and protects the liver against Aeromonas hydrophila-induced hepatic damage in the grass carp Ctenopharyngodon idella.
Topics: Aeromonas hydrophila; Animal Feed; Animals; Antioxidants; Bacterial Load; Caffeine; Carps; Dietary S | 2019 |
Genoprotective and hepatoprotective effects of Guarana (Paullinia cupana Mart. var. sorbilis) on CCl4-induced liver damage in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeine; Carbon Tetrachloride; DNA Dama | 2016 |
Protective effects of coffee-derived compounds on lipopolysaccharide/D-galactosamine induced acute liver injury in rats.
Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Caffeine; Chemical and Drug I | 2009 |
Could quantitative liver function tests gain wide acceptance among hepatologists?
Topics: Biomarkers; Caffeine; Gastroenterology; Humans; Liver; Liver Diseases; Liver Function Tests; Prognos | 2009 |
[GASTRIC SECRETION IN CHILDREN WITH DIABETES MELLITUS].
Topics: Adolescent; Caffeine; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Digestion; Gastric Acidit | 1964 |
Validity of the 13C-caffeine breath test as a noninvasive, quantitative test of liver function.
Topics: Adult; Aged; Breath Tests; Caffeine; Carbon Isotopes; Case-Control Studies; Female; Humans; Kinetics | 2003 |
Coffee: for most, it's safe. Coffee has been blamed for everything from moral turpitude to cancer. But none of the bad raps have stuck. Coffee may even be good for you.
Topics: Caffeine; Cardiovascular System; Coffee; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Li | 2004 |
Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States.
Topics: Alanine Transaminase; Alcohol Drinking; Caffeine; Coffee; Female; Glucose Metabolism Disorders; Hepa | 2005 |
Evaluation of caffeine plasma levels by an automated enzyme immunoassay (EMIT) in comparison with a high-performance liquid chromatographic method.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Immunoenzyme Techniques; Liver Diseases; Rea | 1984 |
[Caffeine--an ubiquitous indicator of liver function].
Topics: Adult; Aged; Caffeine; Female; Galactose; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Func | 1983 |
[Caffeine in chronic liver diseases].
Topics: Caffeine; Humans; Injections, Intravenous; Liver Diseases | 1983 |
Influence of liver disease and environmental factors on hepatic monooxygenase activity in vitro.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 | 1981 |
Caffeine elimination in cirrhotic and non-cirrhotic liver disease of different etiology.
Topics: Adult; Aged; Caffeine; Diagnosis, Differential; Female; Humans; Liver Cirrhosis; Liver Diseases; Liv | 1993 |
The prognostic significance of caffeine half-life in saliva in children with chronic liver disease.
Topics: Adolescent; Aspartate Aminotransferases; Bilirubin; Caffeine; Case-Control Studies; Child; Child, Pr | 1995 |
Caffeine demethylation measured by breath analysis in experimental liver injury in the rat.
Topics: Animals; Breath Tests; Caffeine; Carbon Dioxide; Carbon Radioisotopes; Liver Diseases; Male; Methyla | 1995 |
Antipyrine and caffeine dispositions in clinically normal dogs and dogs with progressive liver disease.
Topics: Analysis of Variance; Animals; Antipyrine; Caffeine; Chemical and Drug Induced Liver Injury; Chromat | 1994 |
Interaction of caffeine with acetaminophen. 1. Correlation of the effect of caffeine on acetaminophen hepatotoxicity and acetaminophen bioactivation following treatment of mice with various cytochrome P450 inducing agents.
Topics: Acetaminophen; Acetone; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflav | 1993 |
Caffeine clearance by two point analysis: a measure of liver function in chronic liver disease.
Topics: Adult; Aged; Caffeine; Chronic Disease; Female; Hepatitis; Humans; Liver; Liver Cirrhosis; Liver Dis | 1996 |
Postmenopausal estrogen therapy selectively stimulates hepatic enlargement in women with autosomal dominant polycystic kidney disease.
Topics: Antipyrine; Caffeine; Cysts; Estrogen Replacement Therapy; Female; Hormones; Humans; Kidney; Liver; | 1997 |
Teas and other beverages suppress D-galactosamine-induced liver injury in rats.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Beverages; Blood G | 1999 |
Coffee, alcohol, and the liver.
Topics: Alanine Transaminase; Alcohol Drinking; Animals; Caffeine; Cebus; Clinical Trials as Topic; Coffee; | 1999 |
[Metabolism studies with coffee and caffeine in healthy subjects, diabetics and patients with liver disease].
Topics: Caffeine; Coffee; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Humans; Insulin; Liver Dis | 1976 |
[Letter: Caffeine in biliary and liver diseases].
Topics: Biliary Tract Diseases; Caffeine; Diet; Fatty Acids, Nonesterified; Humans; Liver Diseases | 1975 |
Simplified approach for evaluation of hepatic drug-oxidizing capacity with a simultaneous measurement of caffeine and its primary demethylated metabolites in carbon tetrachloride-intoxicated rats.
Topics: Administration, Oral; Animals; Caffeine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced L | 1992 |
[Comparison of ICG elimination with biotransformation of model substances and histological features of liver biopsy in liver diseases].
Topics: 7-Alkoxycoumarin O-Dealkylase; Adult; Biopsy; Biotransformation; Caffeine; Coumarins; Dipyrone; Fema | 1991 |
Caffeine clearance by enzyme multiplied immunoassay technique: a simple, inexpensive, and useful indicator of liver function.
Topics: Adult; Aged; Aged, 80 and over; Caffeine; Humans; Immunoenzyme Techniques; Liver Cirrhosis; Liver Di | 1991 |
[Comparison of the value of serum caffeine and bile acid concentrations as indicators of liver injury].
Topics: Adult; Bile Acids and Salts; Caffeine; Chromatography, High Pressure Liquid; Female; Humans; Liver D | 1990 |
Assessment of hepatic function. Comparison of caffeine clearance in serum and saliva during the day and at night.
Topics: Aminopyrine; Breath Tests; Caffeine; Chromatography, High Pressure Liquid; Circadian Rhythm; Female; | 1990 |
Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction.
Topics: Absorption; Antipyrine; Biological Availability; Caffeine; Diphenhydramine; Dose-Response Relationsh | 1990 |
Liver function assessment by drug metabolism.
Topics: Acetamides; Adult; Allopurinol; Aminopyrine; Caffeine; Half-Life; Humans; Indocyanine Green; Lidocai | 1990 |
Hepatic insufficiency after portacaval shunting is prevented by prior intraportal pancreatic islet autotransplantation.
Topics: Animals; Caffeine; Dogs; Female; Glucose Tolerance Test; Indocyanine Green; Islets of Langerhans Tra | 1989 |
A model of cytochrome P-450-centered hepatic dysfunction in drug metabolism induced by cobalt-protoporphyrin administration.
Topics: Aminopyrine; Animals; Breath Tests; Caffeine; Carbon Dioxide; Chemical and Drug Induced Liver Injury | 1989 |
Metabolic activity of microcarrier attached liver cells after intraperitoneal transplantation during severe liver insufficiency in the rat.
Topics: Alanine Transaminase; Ammonia; Animals; Blood Glucose; Caffeine; DNA; Electroencephalography; Evoked | 1989 |
[Theophylline-caffeine interaction in bronchial disease patients with cardiac and hepatic failure].
Topics: Adult; Bronchial Diseases; Caffeine; Drug Interactions; Heart Diseases; Humans; Liver Diseases; Theo | 1985 |
Caffeine intake, fasting plasma caffeine and caffeine clearance in patients with liver diseases.
Topics: Body Weight; Caffeine; Fasting; Humans; Liver Diseases; Liver Function Tests; Saliva | 1988 |
Rapid high-performance liquid chromatography assay for salivary and serum caffeine following an oral load. An indicator of liver function.
Topics: Adult; Aging; Caffeine; Child; Chromatography, High Pressure Liquid; Half-Life; Humans; Indicators a | 1987 |
[Effect of various liver diseases on the activity of 2 subtypes of cytochrome P-450].
Topics: Adult; Biotransformation; Caffeine; Cytochrome P-450 Enzyme System; Dipyrone; Enzyme Induction; Huma | 1987 |
Factors influencing the caffeine test for cytochrome P 448-dependent liver function.
Topics: Caffeine; Cytochrome P-450 CYP1A2; Cytochromes; Drug Interactions; Humans; Kinetics; Liver; Liver Di | 1987 |
Variability of caffeine metabolism in humans.
Topics: Acetylation; Biotransformation; Caffeine; Dealkylation; Female; Half-Life; Humans; Kinetics; Liver D | 1985 |
Increased hepatotoxicity of acetaminophen by concomitant administration of caffeine in the rat.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeine; Chemical and Dr | 1985 |
High-performance liquid chromatographic determination of dimethylxanthine metabolites of caffeine in human plasma.
Topics: Ammonium Sulfate; Caffeine; Chromatography, High Pressure Liquid; Humans; Liver Diseases; Theobromin | 1985 |
Caffeine elimination: a test of liver function.
Topics: Adult; Aged; Caffeine; Female; Humans; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Male; | 1985 |
Fasting plasma caffeine concentration. A guide to the severity of chronic liver disease.
Topics: Adult; Caffeine; Chronic Disease; Fasting; Female; Humans; Liver Cirrhosis; Liver Diseases; Liver Fu | 1985 |
[Editorial: Caffeine in the prisoner's dock--Quousque tandem?].
Topics: Adult; Caffeine; Coffee; Colonic Neoplasms; Female; Humans; Liver Diseases; Male; Middle Aged; Recta | 1974 |
Does coffee influence the lipid metabolism?
Topics: Animals; Caffeine; Cholesterol; Coffee; Coronary Disease; Fatty Acids, Nonesterified; Humans; Intrac | 1969 |
[Differential diagnosis of increased catecholamine excretion in arterial hypertension].
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Arteries; Asthma; Caffeine; Catecholamines; Diagnosis, Diff | 1970 |
[On the therapy of potency disorders in liver diseases].
Topics: Adult; Caffeine; Erectile Dysfunction; Humans; Liver Diseases; Male; Methyltestosterone; Middle Aged | 1968 |