caffeine has been researched along with Leukemia L 1210 in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors carried out experiments on mice DBA/2 and BDF1 with leucosis L1210 and lung carcinoma of Lewis and found that psycotropic preparations tempidone and caffeine did not manifest antitumorous effect and toxicity after the used doses and scheme of treatment." | 7.66 | [Experiment to potentiate the effect of cyclophosphamide combined with tempidon and caffeine in leukemia L1210 and Lewis hepatic carcinoma]. ( Milushev, A; Stoichkov, I; Todorov, D, 1978) |
| "The authors carried out experiments on mice DBA/2 and BDF1 with leucosis L1210 and lung carcinoma of Lewis and found that psycotropic preparations tempidone and caffeine did not manifest antitumorous effect and toxicity after the used doses and scheme of treatment." | 3.66 | [Experiment to potentiate the effect of cyclophosphamide combined with tempidon and caffeine in leukemia L1210 and Lewis hepatic carcinoma]. ( Milushev, A; Stoichkov, I; Todorov, D, 1978) |
| "The therapeutic usefulness of chlorpromazine (CPZ) and caffeine (CAF) in combination with selected nitrosoureas was investigated in mice bearing L1210 leukemia, Lewis lung carcinoma, and B16 melanoma." | 3.66 | Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors. ( Dykes, DJ; Laster, WR; Rose, WC; Schabel, FM; Trader, MW, 1978) |
| " The dose-response curve was bell-shaped for both compounds." | 1.28 | Production of protein-associated DNA breaks by 8-methoxycaffeine, caffeine and 8-chlorocaffeine in isolated nuclei from L1210 cells: comparison with those produced by topoisomerase II inhibitors. ( Kohn, KW; Parodi, S; Pedrini, AM; Poggi, L; Pommier, Y; Russo, P, 1991) |
| "8-MOC has been postulated to produce chromosomal aberrations by DNA topoisomerase II inhibition." | 1.28 | 8-methoxycaffeine-induced protein-associated DNA breaks in isolated L1210 cell nuclei. ( Billi, G; Brega, I; Parodi, S; Piccini, D; Poggi, L; Russo, P; Vigani, A; Zignaigo, G, 1990) |
| "Certain psychotropic drugs when combined with caffeine significantly enhanced the antitumor effect of 1,3-bis(2-chloroethyl)-1-nitrosourea in murine leukemia L1210." | 1.25 | Enhancement of the antitumor effect of 1,3-bis(2-chloroethyl)-1-nitrosourea by various psychotropic drugs in combination with caffeine. ( Cohen, MH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peri, G | 2 |
| Polentarutti, N | 1 |
| Filippeschi, S | 2 |
| Malfiore, C | 1 |
| Amato, G | 1 |
| Pepe, S | 1 |
| Bonati, M | 1 |
| Garattini, S | 2 |
| Mantovani, A | 2 |
| Erba, E | 1 |
| Morasca, L | 1 |
| Spreafico, F | 1 |
| Arnaud, M | 1 |
| Eastman, A | 1 |
| Bresnick, E | 1 |
| Hrubisko, M | 1 |
| McGown, AT | 1 |
| Fox, BW | 1 |
| Stefanková, Z | 1 |
| Barancík, M | 1 |
| Breier, A | 1 |
| Sasada, M | 1 |
| Sawada, H | 1 |
| Nakamura, T | 2 |
| Uchino, H | 2 |
| Tatsumi, K | 1 |
| Tashima, M | 1 |
| Shirakawa, S | 1 |
| Cohen, MH | 3 |
| Ross, WE | 1 |
| Zwelling, LA | 1 |
| Kohn, KW | 2 |
| Stoichkov, I | 1 |
| Milushev, A | 1 |
| Todorov, D | 1 |
| Rose, WC | 1 |
| Trader, MW | 1 |
| Dykes, DJ | 1 |
| Laster, WR | 1 |
| Schabel, FM | 1 |
| Tashiro, T | 1 |
| Sato, Y | 1 |
| Russo, P | 3 |
| Poggi, L | 2 |
| Parodi, S | 3 |
| Pedrini, AM | 2 |
| Pommier, Y | 1 |
| Kunicka, JE | 1 |
| Myc, A | 1 |
| Melamed, MR | 1 |
| Darzynkiewicz, Z | 1 |
| Zignaigo, G | 2 |
| Vigani, A | 1 |
| Billi, G | 1 |
| Brega, I | 1 |
| Piccini, D | 1 |
| Lusuriello, P | 1 |
| Tornaletti, S | 1 |
| DeWys, WD | 1 |
19 other studies available for caffeine and Leukemia L 1210
| Article | Year |
|---|---|
In vitro and in vivo cytotoxicity of possible uracil metabolites of methylxanthines.
Topics: Animals; Caffeine; Cartilage; In Vitro Techniques; Leukemia L1210; Lymphocyte Activation; Mice; Rats | 1983 |
In vitro and in vivo cytotoxicity of 6 amino-5-formyl-methylamino-1,3-dimethyl uracil, a uracilic metabolite of caffeine.
Topics: Animals; Caffeine; Cell Division; Female; Humans; In Vitro Techniques; Leukemia L1210; Mice; Mice, I | 1982 |
Studies on the resistance of a murine leukemia L1210 cell line cis-diamminedichloroplatinum (II).
Topics: Animals; Caffeine; Cell Line; Cisplatin; Drug Resistance; Leukemia L1210; Mice | 1981 |
The role of metallothionein, glutathione, glutathione S-transferases and DNA repair in resistance to platinum drugs in a series of L1210 cell lines made resistant to anticancer platinum agents.
Topics: Animals; Caffeine; Cisplatin; DNA Repair; Drug Resistance; Glutathione; Glutathione Transferase; Leu | 1993 |
Overcoming of P-glycoprotein mediated vincristine resistance of L1210/VCR mouse leukemic cells could be induced by pentoxifyline but not by theophylline and caffeine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Calcium; Calcium Channel | 1996 |
Caffeine potentiation on lethality of L-1210 cells treated with neocarzinostatin.
Topics: Animals; Antibiotics, Antineoplastic; Caffeine; Cells, Cultured; Drug Synergism; Leukemia L1210; Mic | 1976 |
Enhancement by caffeine of neocarzinostatin cytotoxicity in murine leukemia L1210 cells.
Topics: Animals; Antibiotics, Antineoplastic; Caffeine; Cell Division; Cell Line; Cell Survival; DNA Repair; | 1979 |
Enhancement of the antitumor effect of 1,3-bis(2-chloroethyl)-1-nitrosourea by various psychotropic drugs in combination with caffeine.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Caffeine; Carmustine; Dose-Resp | 1975 |
Relationship between cytotoxicity and DNA strand breakage produced by adriamycin and other intercalating agents.
Topics: Animals; Caffeine; Cell Survival; Cells, Cultured; Dactinomycin; DNA Repair; DNA, Neoplasm; DNA, Sin | 1979 |
[Experiment to potentiate the effect of cyclophosphamide combined with tempidon and caffeine in leukemia L1210 and Lewis hepatic carcinoma].
Topics: Animals; Caffeine; Carcinoma; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation, P | 1978 |
Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors.
Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Female; Le | 1978 |
Characterization of acquired resistance to cis-diamminedichloroplatinum(II) in mouse leukemia cell lines.
Topics: Animals; Aphidicolin; Cadmium; Cadmium Chloride; Caffeine; Cisplatin; DNA Repair; Drug Resistance; G | 1992 |
Production of protein-associated DNA breaks by 8-methoxycaffeine, caffeine and 8-chlorocaffeine in isolated nuclei from L1210 cells: comparison with those produced by topoisomerase II inhibitors.
Topics: Animals; Autoradiography; Caffeine; Cell Nucleus; DNA Damage; DNA Topoisomerases, Type II; DNA-Bindi | 1991 |
Caffeine increases sensitivity of DNA to denaturation in chromatin of L1210 cells.
Topics: Acridine Orange; Animals; Caffeine; Chromatin; DNA, Neoplasm; Flow Cytometry; Interphase; Leukemia L | 1990 |
8-methoxycaffeine-induced protein-associated DNA breaks in isolated L1210 cell nuclei.
Topics: Animals; Caffeine; Chromosome Aberrations; Cross-Linking Reagents; DNA Damage; Doxorubicin; Elliptic | 1990 |
Biochemical and enzymatic aspects of caffeine and caffeine derivatives induced DNA strand breaks.
Topics: Animals; Caffeine; DNA Damage; DNA Topoisomerases, Type II; DNA, Single-Stranded; Humans; Leukemia L | 1989 |
A dose-response study of resistance of leukemia L1210 to cyclophosphamide.
Topics: Animals; Caffeine; Cell Survival; Cyclophosphamide; DNA Repair; Dose-Response Relationship, Drug; Le | 1973 |
Brief communication: Enhancement of the antitumor effect of 1,-3-bis(2-chloroethyl)-1-nitrosourea by chlorpromazine and caffeine.
Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Therapy, Combi | 1973 |
Enhancement of the antitumor effect of 1,3-bis(2-chloroethyl)-1-nitrosourea by vitamin A and caffeine.
Topics: Alkylating Agents; Animals; Caffeine; Carmustine; Cell Membrane; DNA Repair; Drug Combinations; Drug | 1972 |