caffeine has been researched along with Kernicterus in 5 studies
Kernicterus: A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
KOENIG, H | 1 |
Stern, L | 3 |
Doray, B | 1 |
Chan, G | 3 |
Schiff, D | 3 |
Rasmussen, LF | 1 |
Wennberg, RP | 1 |
1 review available for caffeine and Kernicterus
Article | Year |
---|---|
Bilirubin metabolism and the induction of kernicterus.
Topics: Acidosis; Animals; Benzoates; Bilirubin; Caffeine; Chromatography, Gel; Coloring Agents; Fatty Acids | 1976 |
4 other studies available for caffeine and Kernicterus
Article | Year |
---|---|
[Studies on bilirubin transport disorders with reference to the hazard of kernicterus in premature and newborn infants].
Topics: Bilirubin; Caffeine; Humans; Infant, Newborn; Kernicterus; Novobiocin; Salicylic Acid; Sulfonamides | 1961 |
Sephadex G-25 quantitative estimation of free bilirubin potential in jaundiced newborn infants sera: a guide to the prevention of kernicterus.
Topics: Bilirubin; Caffeine; Chromatography, Gel; Humans; Infant, Newborn; Jaundice, Neonatal; Kernicterus; | 1972 |
Pharmacologic modification of bilirubin toxicity in tissue culture cells.
Topics: Adenosine Triphosphate; Aminophylline; Animals; Bilirubin; Biological Transport; Caffeine; Carbon Is | 1972 |
Fixed drug combinations and the displacement of bilirubin from albumin.
Topics: Benzoates; Bilirubin; Caffeine; Chromatography, Gel; Diazepam; Drug Synergism; Humans; Infant, Newbo | 1971 |