caffeine has been researched along with Ischemia in 39 studies
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We tested the hypothesis that Ado receptor blockade by caffeine would attenuate reflex MSNA responses to handgrip (HG) and posthandgrip ischemia (PHGI) and that this action would be more prominent in HF subjects than in normal subjects." | 9.09 | Effect of adenosine receptor blockade with caffeine on sympathetic response to handgrip exercise in heart failure. ( Atchison, DJ; Floras, JS; Notarius, CF; Rongen, GA, 2001) |
| "It is believed that adenosine is released in ischemic tissues and contributes to reactive hyperemia." | 7.70 | Intravascular source of adenosine during forearm ischemia in humans: implications for reactive hyperemia. ( Angel, M; Biaggioni, I; Cavalcante, J; Christman, B; Costa, F; Haile, V; Sulur, P, 1999) |
| "The Ca2+ sensitivity of cardiac myofibrillar force production can be decreased by acidosis or inorganic phosphate (P(i)) and increased by caffeine." | 7.69 | Developmental differences and regional similarities in the responses of rat cardiac skinned muscles to acidosis, inorganic phosphate and caffeine. ( Kentish, JC; Palmer, S, 1996) |
| "Caffeine was administered for 3 days and/or PBM for 5 days following HIE." | 5.91 | Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model. ( Beutner, G; Brophy, PD; Dahlstrom, JE; Groves, AM; Johnston, CJ; Kent, AL; Koina, M; Marples, B; O'Reilly, M; Porter, G, 2023) |
| "Caffeine is a psychoactive compound used widely to enhance cognitive functions in human or animal studies." | 5.72 | Effect of intranasal administration of caffeine on mPFC ischemia‑induced cognitive impairment in BALB/c mice. ( Farajdokht, F; Farhoudi, M; Farokhi-Sisakht, F; Kahfi-Ghaneh, R; Mahmoudi, J; Sadigh-Eteghad, S, 2022) |
| "Caffeine-treated and -untreated pups underwent the Vannucci procedure (unilateral carotid ligation, global hypoxia) on P2." | 5.56 | Caffeine Restores Background EEG Activity Independent of Infarct Reduction after Neonatal Hypoxic Ischemic Brain Injury. ( Gonzalez, F; McQuillen, PS; Sun, H, 2020) |
| "A 39-year-old woman suffering from migraine took two suppositories of an ergotamine-containing proprietary drug (Cafergot, containing 2 mg ergotamine tartrate) for the first time again after an abstinence of two years." | 5.28 | [Extremity-threatening ischemia in ergotism. Successful treatment with the intra-arterial administration of nifedipine]. ( Brandt, J; Ernst, R; Mumme, A; Schäfer, K; Zumtobel, V, 1991) |
| " We tested the hypothesis that Ado receptor blockade by caffeine would attenuate reflex MSNA responses to handgrip (HG) and posthandgrip ischemia (PHGI) and that this action would be more prominent in HF subjects than in normal subjects." | 5.09 | Effect of adenosine receptor blockade with caffeine on sympathetic response to handgrip exercise in heart failure. ( Atchison, DJ; Floras, JS; Notarius, CF; Rongen, GA, 2001) |
| " Caffeine can ameliorate hypoxia-ischemia-induced brain WMD; however, its neuroprotective effect and mechanism against hypoxic-ischemic WMD remain unclear." | 4.12 | Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization. ( Fu, J; Liu, N; Xue, X; Yang, L; Yu, X; Zhang, Y, 2022) |
| " The day before the occurrence of these acute lesions, he self medicated with a drug containing ergotamine and caffeine because of a headache." | 3.79 | [Digital necrosis in hand by uncommon mechanism]. ( Lashak, C; Leroux, MB; Mazzurco, M, 2013) |
| "It is believed that adenosine is released in ischemic tissues and contributes to reactive hyperemia." | 3.70 | Intravascular source of adenosine during forearm ischemia in humans: implications for reactive hyperemia. ( Angel, M; Biaggioni, I; Cavalcante, J; Christman, B; Costa, F; Haile, V; Sulur, P, 1999) |
| "The Ca2+ sensitivity of cardiac myofibrillar force production can be decreased by acidosis or inorganic phosphate (P(i)) and increased by caffeine." | 3.69 | Developmental differences and regional similarities in the responses of rat cardiac skinned muscles to acidosis, inorganic phosphate and caffeine. ( Kentish, JC; Palmer, S, 1996) |
| "Caffeine was administered for 3 days and/or PBM for 5 days following HIE." | 1.91 | Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model. ( Beutner, G; Brophy, PD; Dahlstrom, JE; Groves, AM; Johnston, CJ; Kent, AL; Koina, M; Marples, B; O'Reilly, M; Porter, G, 2023) |
| "Caffeine is a psychoactive compound used widely to enhance cognitive functions in human or animal studies." | 1.72 | Effect of intranasal administration of caffeine on mPFC ischemia‑induced cognitive impairment in BALB/c mice. ( Farajdokht, F; Farhoudi, M; Farokhi-Sisakht, F; Kahfi-Ghaneh, R; Mahmoudi, J; Sadigh-Eteghad, S, 2022) |
| "Caffeine-treated and -untreated pups underwent the Vannucci procedure (unilateral carotid ligation, global hypoxia) on P2." | 1.56 | Caffeine Restores Background EEG Activity Independent of Infarct Reduction after Neonatal Hypoxic Ischemic Brain Injury. ( Gonzalez, F; McQuillen, PS; Sun, H, 2020) |
| "Transient retinal ischemia is a major complication of retinal degenerative diseases and contributes to visual impairment and blindness." | 1.46 | Treatment with A ( Aires, ID; Ambrósio, AF; Baqi, Y; Boia, R; Cunha, RA; Elvas, F; Madeira, MH; Müller, CE; Rodrigues-Neves, AC; Santiago, AR; Szabó, EC; Tomé, ÂR; Tralhão, P, 2017) |
| "Ergot alkaloids are commonly used for migraine headaches and have vasoconstrictive properties." | 1.31 | An unusual case of clarithromycin associated ergotism. ( Ausband, SC; Goodman, PE, 2001) |
| "She had a history of migraine going back 10 years." | 1.29 | [Ergotamine-induced rectal stenosis in a patient with long-term migraine]. ( Ell, C; Hahn, EG; Machnig, T; May, A; Steininger, H; von Streitberg, U, 1993) |
| "A 39-year-old woman suffering from migraine took two suppositories of an ergotamine-containing proprietary drug (Cafergot, containing 2 mg ergotamine tartrate) for the first time again after an abstinence of two years." | 1.28 | [Extremity-threatening ischemia in ergotism. Successful treatment with the intra-arterial administration of nifedipine]. ( Brandt, J; Ernst, R; Mumme, A; Schäfer, K; Zumtobel, V, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (23.08) | 18.7374 |
| 1990's | 7 (17.95) | 18.2507 |
| 2000's | 9 (23.08) | 29.6817 |
| 2010's | 6 (15.38) | 24.3611 |
| 2020's | 8 (20.51) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, L | 1 |
| Yu, X | 1 |
| Zhang, Y | 1 |
| Liu, N | 1 |
| Xue, X | 1 |
| Fu, J | 1 |
| Farokhi-Sisakht, F | 1 |
| Farhoudi, M | 1 |
| Mahmoudi, J | 1 |
| Farajdokht, F | 1 |
| Kahfi-Ghaneh, R | 1 |
| Sadigh-Eteghad, S | 1 |
| Weese-Myers, ME | 1 |
| Cryan, MT | 1 |
| Witt, CE | 1 |
| Caldwell, KCN | 1 |
| Modi, B | 1 |
| Ross, AE | 1 |
| Sabir, H | 1 |
| Maes, E | 1 |
| Zweyer, M | 1 |
| Schleehuber, Y | 1 |
| Imam, FB | 1 |
| Silverman, J | 1 |
| White, Y | 1 |
| Pang, R | 1 |
| Pasca, AM | 1 |
| Robertson, NJ | 1 |
| Maltepe, E | 1 |
| Bernis, ME | 1 |
| Groves, AM | 1 |
| Johnston, CJ | 1 |
| Beutner, G | 1 |
| Dahlstrom, JE | 1 |
| Koina, M | 1 |
| O'Reilly, M | 1 |
| Marples, B | 1 |
| Porter, G | 1 |
| Brophy, PD | 1 |
| Kent, AL | 1 |
| Sun, H | 1 |
| Gonzalez, F | 1 |
| McQuillen, PS | 1 |
| Wang, LT | 1 |
| He, PC | 1 |
| Li, AQ | 1 |
| Cao, KX | 1 |
| Yan, JW | 1 |
| Guo, S | 1 |
| Jiang, L | 1 |
| Yao, L | 1 |
| Dai, XY | 1 |
| Feng, D | 1 |
| Xu, YM | 1 |
| Tan, N | 1 |
| Pereira-Figueiredo, D | 1 |
| Nascimento, AA | 1 |
| Cunha-Rodrigues, MC | 1 |
| Brito, R | 1 |
| Calaza, KC | 1 |
| Boia, R | 1 |
| Elvas, F | 1 |
| Madeira, MH | 1 |
| Aires, ID | 1 |
| Rodrigues-Neves, AC | 1 |
| Tralhão, P | 1 |
| Szabó, EC | 1 |
| Baqi, Y | 1 |
| Müller, CE | 1 |
| Tomé, ÂR | 1 |
| Cunha, RA | 1 |
| Ambrósio, AF | 1 |
| Santiago, AR | 1 |
| Leroux, MB | 1 |
| Lashak, C | 1 |
| Mazzurco, M | 1 |
| Asensio-Sánchez, VM | 1 |
| Zelken, JA | 1 |
| Berli, JU | 1 |
| Meijer, P | 2 |
| Wouters, CW | 2 |
| van den Broek, PH | 2 |
| de Rooij, M | 1 |
| Scheffer, GJ | 2 |
| Smits, P | 2 |
| Rongen, GA | 3 |
| Rodríguez de Cossío, A | 1 |
| Rodríguez Sánchez, R | 1 |
| Alonso Moreno, FJ | 1 |
| Papeix, C | 1 |
| Guépratte, N | 1 |
| Gout, O | 1 |
| Lebuisson, DA | 1 |
| Mehiri, SN | 1 |
| Barreiro, E | 1 |
| Hayot, M | 1 |
| Voyer, M | 1 |
| Comtois, AS | 1 |
| Grassino, AE | 1 |
| Czaika, G | 1 |
| Liu, J | 1 |
| Kam, KW | 1 |
| Borchert, GH | 1 |
| Kravtsov, GM | 1 |
| Ballard, HJ | 1 |
| Wong, TM | 1 |
| Wirkner, K | 1 |
| Köfalvi, A | 1 |
| Fischer, W | 1 |
| Günther, A | 1 |
| Franke, H | 1 |
| Gröger-Arndt, H | 1 |
| Nörenberg, W | 1 |
| Madarász, E | 1 |
| Vizi, ES | 1 |
| Schneider, D | 1 |
| Sperlágh, B | 1 |
| Illes, P | 1 |
| Riksen, NP | 1 |
| Kemerer, VF | 1 |
| Dagher, FJ | 1 |
| Pais, SO | 1 |
| Heinz, M | 1 |
| Theiss, W | 1 |
| Golder, W | 1 |
| Schömig, A | 1 |
| Machnig, T | 1 |
| May, A | 1 |
| Steininger, H | 1 |
| von Streitberg, U | 1 |
| Hahn, EG | 1 |
| Ell, C | 1 |
| Palmer, S | 1 |
| Kentish, JC | 1 |
| Voyvodic, F | 1 |
| Hayward, M | 1 |
| D'Amore, MJ | 1 |
| Borge, MA | 1 |
| Messersmith, RN | 1 |
| Costa, F | 1 |
| Sulur, P | 1 |
| Angel, M | 1 |
| Cavalcante, J | 1 |
| Haile, V | 1 |
| Christman, B | 1 |
| Biaggioni, I | 1 |
| Karam, B | 1 |
| Farah, E | 1 |
| Ashoush, R | 1 |
| Jebara, V | 1 |
| Ghayad, E | 1 |
| Garcia, GD | 1 |
| Goff, JM | 1 |
| Hadro, NC | 1 |
| O'donnell, SD | 1 |
| Greatorex, PS | 1 |
| Notarius, CF | 1 |
| Atchison, DJ | 1 |
| Floras, JS | 1 |
| Ausband, SC | 1 |
| Goodman, PE | 1 |
| Mumme, A | 1 |
| Ernst, R | 1 |
| Brandt, J | 1 |
| Schäfer, K | 1 |
| Zumtobel, V | 1 |
| Bosman, DK | 1 |
| de Haan, JG | 1 |
| Smit, J | 1 |
| Jorning, GG | 1 |
| Maas, MA | 1 |
| Chamuleau, RA | 1 |
| Rudolphi, KA | 1 |
| Keil, M | 1 |
| Fastbom, J | 1 |
| Fredholm, BB | 1 |
| Jones, NS | 1 |
| Lewis, LD | 1 |
| Wells, KE | 1 |
| Steed, DL | 1 |
| Zajko, AB | 1 |
| Webster, MW | 1 |
| Kaji, T | 1 |
| Ashida, H | 1 |
| Fujikawa, M | 1 |
| Satoh, Y | 1 |
| Saeki, A | 1 |
| Ishikawa, T | 1 |
| Kawada, T | 1 |
| Doig, SG | 1 |
| Fell, G | 1 |
| French, J | 1 |
| Carliner, N | 1 |
| Denune, DP | 1 |
| Finch, CS | 1 |
| Goldberg, LI | 1 |
| Kincaid-Smith, P | 1 |
| Saker, BM | 1 |
| McKenzie, IF | 1 |
| Muriden, KD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is Augmentation of PORH by Rosuvastatin Adenosine-receptor Mediated?[NCT00851175] | Phase 4 | 8 participants (Anticipated) | Interventional | 2009-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for caffeine and Ischemia
| Article | Year |
|---|---|
Caffeine and Its Neuroprotective Role in Ischemic Events: A Mechanism Dependent on Adenosine Receptors.
Topics: Adenosine; Brain; Caffeine; Central Nervous System; Glucose; Humans; Ischemia; Neuroprotective Agent | 2022 |
[Acute ischemia of an arm as an unusual manifestation of ergotism].
Topics: Acute Disease; Adult; Arm; Brachial Artery; Caffeine; Drug Combinations; Drug Therapy, Combination; | 1994 |
4 trials available for caffeine and Ischemia
| Article | Year |
|---|---|
Upregulation of ecto-5'-nucleotidase by rosuvastatin increases the vasodilator response to ischemia.
Topics: 5'-Nucleotidase; Adenosine; Blood Flow Velocity; Brachial Artery; Caffeine; Central Nervous System S | 2010 |
Dipyridamole enhances ischaemia-induced reactive hyperaemia by increased adenosine receptor stimulation.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Forearm; Humans; Hyperemia | 2008 |
Effect of adenosine receptor blockade with caffeine on sympathetic response to handgrip exercise in heart failure.
Topics: Adenosine; Blood Pressure; Caffeine; Exercise Test; Female; Hand Strength; Heart Failure; Heart Rate | 2001 |
Lesions in the blood supply of the papilla in experimental analgesic nephropathy.
Topics: Animals; Aspirin; Blood Vessels; Caffeine; Clinical Trials as Topic; Humans; Ischemia; Kidney; Kidne | 1968 |
33 other studies available for caffeine and Ischemia
| Article | Year |
|---|---|
Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization.
Topics: Animals; Animals, Newborn; Caffeine; Hypoxia-Ischemia, Brain; Inflammasomes; Ischemia; Microglia; NL | 2022 |
Effect of intranasal administration of caffeine on mPFC ischemia‑induced cognitive impairment in BALB/c mice.
Topics: Administration, Intranasal; Animals; Caffeine; Cognitive Dysfunction; Interleukin-10; Interleukin-6; | 2022 |
Dynamic and Rapid Detection of Guanosine during Ischemia.
Topics: Brain Injuries; Brain Ischemia; Caffeine; Calcium; Guanosine; Humans; Ischemia | 2023 |
Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia-ischemia in newborn rats: a multi-drug randomized controlled screening trial.
Topics: Allopurinol; Animals; Animals, Newborn; Asphyxia Neonatorum; Brain; Brain Injuries; Caffeine; Clemas | 2023 |
Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model.
Topics: Acute Kidney Injury; Albumins; Animals; Animals, Newborn; Biomarkers; Caffeine; Humans; Hypoxia-Isch | 2023 |
Caffeine Restores Background EEG Activity Independent of Infarct Reduction after Neonatal Hypoxic Ischemic Brain Injury.
Topics: Animals; Brain; Brain Injuries; Caffeine; Disease Models, Animal; Hypoxia-Ischemia, Brain; Infarctio | 2020 |
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics.
Topics: Animals; Caffeine; Cell Movement; Endothelium; Hindlimb; Human Umbilical Vein Endothelial Cells; Hum | 2021 |
Treatment with A
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Humans; Inflammation; Ischemia; Mal | 2017 |
[Digital necrosis in hand by uncommon mechanism].
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Analgesics, Non-Narcotic; Bisoprolol; Caffeine; Centr | 2013 |
Energy drinks and visual health.
Topics: Caffeine; Energy Drinks; Humans; Ischemia; Macula Lutea; Male; Middle Aged; Scotoma; Vasoconstrictio | 2014 |
Coffee, tea, and chocolate after microsurgery: why not?
Topics: Cacao; Caffeine; Coffee; Free Tissue Flaps; Humans; Ischemia; Microsurgery; Postoperative Care; Post | 2015 |
[Peripheral ischaemia after chronic ergot poisoning].
Topics: Blood Vessels; Caffeine; Chronic Disease; Drug Combinations; Ergotamine; Ergotism; Female; Humans; I | 2010 |
[Managing an ophthalmic migraine].
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Contraindications; Cortical Sp | 2003 |
Time-based gene expression programme following diaphragm injury in a rat model.
Topics: Animals; Biomarkers; Caffeine; Calpain; Connectin; Diaphragm; Disease Models, Animal; Fibroblast Gro | 2005 |
Further study on the role of HSP70 on Ca2+ homeostasis in rat ventricular myocytes subjected to simulated ischemia.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; A | 2006 |
Supersensitivity of P2X receptors in cerebrocortical cell cultures after in vitro ischemia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Anestheti | 2005 |
Successful treatment of ergotism with nifedipine.
Topics: Angiography; Aortography; Caffeine; Drug Combinations; Ergotamine; Ergotism; Female; Humans; Ischemi | 1984 |
[Ergotamine-induced rectal stenosis in a patient with long-term migraine].
Topics: Adult; Aminopyrine; Biopsy; Caffeine; Colonoscopy; Dilatation; Drug Combinations; Ergotamine; Female | 1993 |
Developmental differences and regional similarities in the responses of rat cardiac skinned muscles to acidosis, inorganic phosphate and caffeine.
Topics: Acidosis; Animals; Atrial Function; Caffeine; Calcium; Heart Atria; Heart Ventricles; Hypoxia; In Vi | 1996 |
Case report: upper extremity ischaemia secondary to ergotamine poisoning.
Topics: Angiography, Digital Subtraction; Anticoagulants; Arm; Caffeine; Drug Combinations; Ergotamine; Hepa | 1996 |
Limb-threatening lower extremity ischemia successfully treated with intra-arterial infusion--case reports.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Drug Combinations; Ergotamine; Female; Follow-Up | 1999 |
Intravascular source of adenosine during forearm ischemia in humans: implications for reactive hyperemia.
Topics: Adenosine; Adult; Caffeine; Female; Forearm; Humans; Hyperemia; Ischemia; Male; Microdialysis; Muscl | 1999 |
Ergotism precipitated by erythromycin: a rare case of vasospasm.
Topics: Abscess; Adult; Anti-Bacterial Agents; Caffeine; Drug Combinations; Ergotamine; Ergotism; Erythromyc | 2000 |
Chronic ergot toxicity: A rare cause of lower extremity ischemia.
Topics: Adult; Caffeine; Chronic Disease; Cyclizine; Drug Combinations; Ergotamine; Ergotism; Female; Foot U | 2000 |
An unusual case of clarithromycin associated ergotism.
Topics: Adult; Caffeine; Clarithromycin; Drug Combinations; Drug Interactions; Ergotamine; Ergotism; Female; | 2001 |
[Extremity-threatening ischemia in ergotism. Successful treatment with the intra-arterial administration of nifedipine].
Topics: Acute Disease; Adult; Arm; Caffeine; Drug Combinations; Ergotamine; Ergotism; Female; Humans; Infusi | 1991 |
Metabolic activity of microcarrier attached liver cells after intraperitoneal transplantation during severe liver insufficiency in the rat.
Topics: Alanine Transaminase; Ammonia; Animals; Blood Glucose; Caffeine; DNA; Electroencephalography; Evoked | 1989 |
Ischaemic damage in gerbil hippocampus is reduced following upregulation of adenosine (A1) receptors by caffeine treatment.
Topics: Administration, Oral; Animals; Autoradiography; Caffeine; Gerbillinae; Hippocampus; Ischemia; Male; | 1989 |
Ergotamine-induced peripheral ischaemia reversed by oral thymoxamine hydrochloride.
Topics: Adult; Caffeine; Drug Combinations; Ergotamine; Female; Humans; Ischemia; Leg; Moxisylyte; Paresthes | 1986 |
Recognition and treatment of arterial insufficiency from cafergot.
Topics: Adult; Arterial Occlusive Diseases; Caffeine; Drug Combinations; Drug Hypersensitivity; Ergotamine; | 1986 |
[Intra-arterial infusion of SNP for peripheral ischemia caused by acute ergotism].
Topics: Adult; Caffeine; Drug Combinations; Ergotamine; Ergotism; Extremities; Female; Ferricyanides; Humans | 1985 |
An unusual angiographic appearance of ergot poisoning.
Topics: Angiography; Arm; Brachial Artery; Caffeine; Drug Combinations; Ergotamine; Female; Humans; Ischemia | 1985 |
Sodium nitroprusside treatment of ergotamine-induced peripheral ischemia.
Topics: Arm; Caffeine; Ergotamine; Female; Ferricyanides; Humans; Infusions, Parenteral; Ischemia; Leg; Meth | 1974 |