caffeine has been researched along with Insulin Resistance in 77 studies
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This systematic review aimed to study caffeine's effect on the cardiometabolic markers of the metabolic syndrome and to evaluate caffeine's application as a potential therapeutic agent in rat models." | 9.41 | Systematic review of the effect of caffeine therapy effect on cardiometabolic markers in rat models of the metabolic syndrome. ( Al Ansari, AM; Alabbasi, AMA; Alhadi, IA; AlSaleh, AFF, 2023) |
| "The effects of alkaloid caffeine on insulin sensitivity have been investigated primarily in men, and with a single caffeine dose most commonly of 5-6 mg·kg(-1) of body weight (BW)." | 9.17 | Caffeine ingestion impairs insulin sensitivity in a dose-dependent manner in both men and women. ( Allen, B; Beaudoin, MS; Graham, TE; Mazzetti, G; Sullivan, PJ, 2013) |
| "Caffeine ingestion decreases the insulin sensitivity index (ISI) for an oral-glucose-tolerance test (OGTT) and decreases insulin-induced glucose disposal in lean male subjects during a hyperinsulinemic clamp." | 9.11 | Caffeine ingestion increases the insulin response to an oral-glucose-tolerance test in obese men before and after weight loss. ( Belfie, LM; Chown, SE; Conquer, JA; Duncan, AM; Graham, TE; McLaren, DH; Petrie, HJ, 2004) |
| "Caffeine decreased insulin sensitivity by 15% (P < 0." | 9.10 | Caffeine can decrease insulin sensitivity in humans. ( De Galan, BE; Keijzers, GB; Smits, P; Tack, CJ, 2002) |
| " Randomized controlled trials (RCTs) that investigated the effect of caffeine on insulin sensitivity in healthy humans without diabetes were included." | 8.93 | Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: a systematic review and meta-analysis. ( Liang, S; Shi, X; Xue, W; Zhang, X; Zhao, J, 2016) |
| " Trials in people with type II diabetes demonstrated that the ingestion of caffeine (approximately 200-500 mg) significantly increased blood glucose concentrations by 16-28% of the area under the curve (AUC) and insulin concentrations by 19-48% of the AUC when taken prior to a glucose load, at the same time as decreasing insulin sensitivity by 14-37%." | 8.89 | Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013) |
| "High intakes of dietary caffeine was associated with lower LDL, SBP, insulin resistance and higher HDL concentrations among overweight and obese individuals." | 8.31 | Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals. ( Abid, MK; Almalki, SG; Alshahrani, SH; Atia, YA; Badir, RA; Hussien, BM; Ramaiah, P; Romero-Parra, RM; Shahab, S; Tayyib, NA, 2023) |
| "The relationship between caffeine and insulin resistance (IR) has been assessed only in terms of caffeine intake, and the association between caffeine and beta cell function (BCF) remains unclear." | 7.96 | Caffeine and Caffeine Metabolites in Relation to Insulin Resistance and Beta Cell Function in U.S. Adults. ( Lee, S; Min, JY; Min, KB, 2020) |
| "Subjects with High-GRS may be susceptible to increased insulin resistance by 50% and its risk may be exacerbated by consuming more than 10 cups coffee/week or 220 mg caffeine/day." | 7.91 | High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults. ( Daily, JW; Liu, M; Park, S, 2019) |
| "Caffeine, a non-selective adenosine antagonist, has distinct effects on insulin sensitivity when applied acutely or chronically." | 7.81 | Disclosing caffeine action on insulin sensitivity: effects on rat skeletal muscle. ( Conde, SV; Gonzalez, C; Guarino, MP; Melo, BF; Obeso, A; Ribeiro, MJ; Sacramento, JF; Yubero, S, 2015) |
| "We tested the hypothesis that long-term caffeine intake prevents the development of insulin resistance and hypertension in two pathological animal models: the high-fat (HF) and the high-sucrose (HSu) diet rat." | 7.78 | Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats. ( Conde, SV; Gonzalez, C; Guarino, MP; Monteiro, EC; Mota Carmo, M; Nunes da Silva, T, 2012) |
| "Outside pregnancy, acute caffeine consumption is associated with insulin resistance." | 7.77 | Caffeine and insulin resistance in pregnancy. ( Catov, J; Laughon, SK; Parana, S; Powers, RW; Roberts, JM, 2011) |
| "Non-alcoholic fatty liver disease (NAFLD) is much more frequent and more severe, including cirrhosis, hepatocellular carcinoma in patients with type 2 diabetes." | 7.01 | Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-c ( Adibi, H; Hekmatdoost, A; Mansour, A; Merat, S; Mohajeri-Tehrani, MR; Poustchi, H; Qorbani, M; Samadi, M, 2021) |
| "Obesity was induced in mice by high-fat diet and the tested compounds (KD-64 and caffeine) were administrated for 21 days." | 5.56 | KD-64-A new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist-Caffeine does not reduce diet-induced obesity in mice. ( Bednarski, M; Drabczyńska, A; Dziubina, A; Kieć-Kononowicz, K; Kotańska, M; Mika, K; Reguła, K; Sapa, J; Szafarz, M; Zygmunt, M, 2020) |
| "This systematic review aimed to study caffeine's effect on the cardiometabolic markers of the metabolic syndrome and to evaluate caffeine's application as a potential therapeutic agent in rat models." | 5.41 | Systematic review of the effect of caffeine therapy effect on cardiometabolic markers in rat models of the metabolic syndrome. ( Al Ansari, AM; Alabbasi, AMA; Alhadi, IA; AlSaleh, AFF, 2023) |
| "Caffeine displays significant antioxidant ability in protecting membranes against oxidative damage and can lower the risk of insulin resistance." | 5.40 | Caffeine intake improves fructose-induced hypertension and insulin resistance by enhancing central insulin signaling. ( Chen, BR; Cheng, PW; Cheng, WH; Ho, WY; Liou, JC; Liu, CP; Lu, PJ; Sun, GC; Tseng, CJ; Yeh, TC, 2014) |
| "Insulin sensitivity was assessed by means of the insulin tolerance test." | 5.39 | Chronic caffeine intake reverses age-induced insulin resistance in the rat: effect on skeletal muscle Glut4 transporters and AMPK activity. ( Conde, SV; Guarino, MP; Ribeiro, MJ; Sacramento, JF, 2013) |
| "The treatment with caffeine in the rats fed the high-carbohydrate, high-fat diet decreased body fat and systolic blood pressure, improved glucose tolerance and insulin sensitivity, and attenuated cardiovascular and hepatic abnormalities, although the plasma lipid concentrations were further increased." | 5.38 | Caffeine attenuates metabolic syndrome in diet-induced obese rats. ( Brown, L; Kauter, K; Panchal, SK; Ward, LC; Wong, WY, 2012) |
| "The association of CC with nonalcoholic fatty liver disease (NAFLD) has not been established." | 5.38 | Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis. ( Calcagno, CJ; Harrison, SA; Jones, FJ; Molloy, JW; Torres, DM; Williams, CD, 2012) |
| "Epidemiologic and experimental data have suggested that chlorogenic acid, which is a polyphenol contained in green coffee beans, prevents diet-induced hepatic steatosis and insulin resistance." | 5.19 | Coffee consumption attenuates short-term fructose-induced liver insulin resistance in healthy men. ( Binnert, C; Boesch, C; Boss, A; Carrel, G; Darimont, C; Egli, L; Kreis, R; Lecoultre, V; MacMillan, EL; Tappy, L, 2014) |
| "The effects of alkaloid caffeine on insulin sensitivity have been investigated primarily in men, and with a single caffeine dose most commonly of 5-6 mg·kg(-1) of body weight (BW)." | 5.17 | Caffeine ingestion impairs insulin sensitivity in a dose-dependent manner in both men and women. ( Allen, B; Beaudoin, MS; Graham, TE; Mazzetti, G; Sullivan, PJ, 2013) |
| "Caffeine significantly increased the concentration of plasma epinephrine (by 42%, 39%, and 49%), serum-free fatty acids (by 53%, 44%, and 50%), and plasma lactate (by 46%, 36%, and 48%), and insulin resistance (homeostasis model assessment-IR) (by 21%, 26%, and 23%) during rest, after 5 min of cycling, and at exhaustion." | 5.12 | Metabolic effects of caffeine ingestion and physical work in 75-year old citizens. A randomized, double-blind, placebo-controlled, cross-over study. ( Jensen, MB; Madsen, MR; Norager, CB; Weimann, A, 2006) |
| "Caffeine ingestion decreases the insulin sensitivity index (ISI) for an oral-glucose-tolerance test (OGTT) and decreases insulin-induced glucose disposal in lean male subjects during a hyperinsulinemic clamp." | 5.11 | Caffeine ingestion increases the insulin response to an oral-glucose-tolerance test in obese men before and after weight loss. ( Belfie, LM; Chown, SE; Conquer, JA; Duncan, AM; Graham, TE; McLaren, DH; Petrie, HJ, 2004) |
| "Caffeine ingestion negatively affects insulin sensitivity during an oral glucose tolerance test (OGTT) in lean and obese men, but this has not been studied in individuals with type 2 diabetes." | 5.11 | Caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetes. ( Battram, DS; Graham, TE; McLaren, DH; Robinson, LE; Sathasivam, P; Savani, S, 2004) |
| "Caffeine decreased insulin sensitivity by 15% (P < 0." | 5.10 | Caffeine can decrease insulin sensitivity in humans. ( De Galan, BE; Keijzers, GB; Smits, P; Tack, CJ, 2002) |
| " These beverages include compounds that may have contradictory effects on insulin and glucose: Caffeine impairs insulin sensitivity, but polyphenolic molecules within tea, coffee, and cocoa augment the effects of insulin." | 4.98 | The Potential Effects of Caffeinated Beverages on Insulin Sensitivity. ( Buslach, N; Cherniack, EP; Lee, HF, 2018) |
| " Randomized controlled trials (RCTs) that investigated the effect of caffeine on insulin sensitivity in healthy humans without diabetes were included." | 4.93 | Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: a systematic review and meta-analysis. ( Liang, S; Shi, X; Xue, W; Zhang, X; Zhao, J, 2016) |
| " Trials in people with type II diabetes demonstrated that the ingestion of caffeine (approximately 200-500 mg) significantly increased blood glucose concentrations by 16-28% of the area under the curve (AUC) and insulin concentrations by 19-48% of the AUC when taken prior to a glucose load, at the same time as decreasing insulin sensitivity by 14-37%." | 4.89 | Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013) |
| "A comprehensive literature search was conducted to identify relevant trials of GTCs with or without caffeine on markers of glycemic control [fasting blood glucose (FBG), fasting blood insulin (FBI), glycated hemoglobin (Hb A1c), and homeostatic model assessment of insulin resistance (HOMA-IR)]." | 4.89 | Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials. ( Huang, XH; Hui, R; Li, SH; Wu, YJ; Xu, YL; Zheng, XX, 2013) |
| " They also exist despite clear evidence showing that caffeine causes acute postprandial hyperglycemia and lower whole-body insulin sensitivity." | 4.84 | Coffee, glucose homeostasis, and insulin resistance: physiological mechanisms and mediators. ( Shearer, J; Tunnicliffe, JM, 2008) |
| "High intakes of dietary caffeine was associated with lower LDL, SBP, insulin resistance and higher HDL concentrations among overweight and obese individuals." | 4.31 | Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals. ( Abid, MK; Almalki, SG; Alshahrani, SH; Atia, YA; Badir, RA; Hussien, BM; Ramaiah, P; Romero-Parra, RM; Shahab, S; Tayyib, NA, 2023) |
| "The relationship between caffeine and insulin resistance (IR) has been assessed only in terms of caffeine intake, and the association between caffeine and beta cell function (BCF) remains unclear." | 3.96 | Caffeine and Caffeine Metabolites in Relation to Insulin Resistance and Beta Cell Function in U.S. Adults. ( Lee, S; Min, JY; Min, KB, 2020) |
| "Subjects with High-GRS may be susceptible to increased insulin resistance by 50% and its risk may be exacerbated by consuming more than 10 cups coffee/week or 220 mg caffeine/day." | 3.91 | High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults. ( Daily, JW; Liu, M; Park, S, 2019) |
| " Caffeine has anti-inflammation, antihepatic steatosis, and anti-insulin resistance effects." | 3.88 | Effects and mechanisms of caffeine to improve immunological and metabolic abnormalities in diet-induced obese rats. ( Hou, MC; Hsieh, YC; Huang, CC; Huang, SF; Lee, FY; Lee, KC; Lee, SD; Li, TH; Lin, HC; Lin, MW; Liu, CW; Su, YB; Tsai, CY; Tsai, HC; Yang, YY, 2018) |
| "Caffeine, a non-selective adenosine antagonist, has distinct effects on insulin sensitivity when applied acutely or chronically." | 3.81 | Disclosing caffeine action on insulin sensitivity: effects on rat skeletal muscle. ( Conde, SV; Gonzalez, C; Guarino, MP; Melo, BF; Obeso, A; Ribeiro, MJ; Sacramento, JF; Yubero, S, 2015) |
| "Caffeine administration seems to decrease insulin sensitivity as indicated by the sustenance of glucose status despite the presence of high insulin levels." | 3.80 | Timing of caffeine ingestion alters postprandial metabolism in rats. ( Jarrar, SF; Obeid, OA, 2014) |
| " Despite a more favorable body composition, rats displayed profound systemic insulin resistance, likely due to caffeine." | 3.80 | Chronic coffee consumption in the diet-induced obese rat: impact on gut microbiota and serum metabolomics. ( Ardell, KL; Bomhof, MR; Cowan, TE; Palmnäs, MS; Reimer, RA; Shearer, J; Vogel, HJ; Yang, J, 2014) |
| "We tested the hypothesis that long-term caffeine intake prevents the development of insulin resistance and hypertension in two pathological animal models: the high-fat (HF) and the high-sucrose (HSu) diet rat." | 3.78 | Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats. ( Conde, SV; Gonzalez, C; Guarino, MP; Monteiro, EC; Mota Carmo, M; Nunes da Silva, T, 2012) |
| "Outside pregnancy, acute caffeine consumption is associated with insulin resistance." | 3.77 | Caffeine and insulin resistance in pregnancy. ( Catov, J; Laughon, SK; Parana, S; Powers, RW; Roberts, JM, 2011) |
| " Currently published data has been stressed that the metyloxantine consumption increases the risk of coronary heart disease, arterial hypertension, arterial stiffness, and an elevation of cholesterol and homocysteine plasma concentration." | 3.75 | [Side effects of caffeine]. ( Burdan, F; Dworzański, W; Opielak, G, 2009) |
| "Non-alcoholic fatty liver disease (NAFLD) is much more frequent and more severe, including cirrhosis, hepatocellular carcinoma in patients with type 2 diabetes." | 3.01 | Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-c ( Adibi, H; Hekmatdoost, A; Mansour, A; Merat, S; Mohajeri-Tehrani, MR; Poustchi, H; Qorbani, M; Samadi, M, 2021) |
| "Remarkably, the combined effects of sleep fragmentation and coffee on glucose control upon waking per se have never been investigated." | 2.94 | Glucose control upon waking is unaffected by hourly sleep fragmentation during the night, but is impaired by morning caffeinated coffee. ( Betts, JA; Chen, YC; Gonzalez, JT; Heath, P; Hengist, A; Perkin, O; Smith, HA; Thomas, J; Walhin, JP, 2020) |
| "Insulin sensitivity was higher with decaffeinated coffee than with water (P<0·05)." | 2.87 | Decaffeinated coffee improves insulin sensitivity in healthy men. ( Amato, AA; Bluck, LJC; da Costa, THM; Dórea, JG; Lofrano-Porto, A; Paiva, CLRDS; Reis, CEG; Wassell, S, 2018) |
| "Insulin resistance was quantified with the homeostasis model." | 2.82 | Simultaneous coffee caffeine intake and sleep deprivation alter glucose homeostasis in Iranian men: a randomized crossover trial. ( Karandish, M; Karim, NA; Noor, MI; Rasaei, B; Talib, RA, 2016) |
| "Obesity, non-alcoholic fatty liver and steatohepatitis as well as diabetes mellitus together also form a significant risk for HCC, due to the gradually increasing number of patients." | 2.46 | [Role of environmental factors in the etiology of hepatocellular carcinoma]. ( Tornai, I, 2010) |
| "Obesity is a state of accumulating excessive body fat, charactering by a high blood lipid and associating with various metabolic diseases." | 1.91 | Improvement of obesity by Liupao tea is through the IRS-1/PI3K/AKT/GLUT4 signaling pathway according to network pharmacology and experimental verification. ( Ni, W; Teng, C; Wu, Z; Ye, W; Yu, C; Yu, W; Zeng, Y, 2023) |
| "Obesity was induced in mice by high-fat diet and the tested compounds (KD-64 and caffeine) were administrated for 21 days." | 1.56 | KD-64-A new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist-Caffeine does not reduce diet-induced obesity in mice. ( Bednarski, M; Drabczyńska, A; Dziubina, A; Kieć-Kononowicz, K; Kotańska, M; Mika, K; Reguła, K; Sapa, J; Szafarz, M; Zygmunt, M, 2020) |
| "Ursolic acid (1) was identified as the responsible for the activity of maté and guayusa extracts in the activation of TGR5, a nuclear receptor of relevance for the prevention and management of diabetes and metabolic syndrome because of its involvement in the regulation of energy expenditure and insulin sensitivity." | 1.51 | Bioactive triterpenoids from the caffeine-rich plants guayusa and maté. ( Appendino, G; Chianese, G; Collado, JA; Golin-Pacheco, SD; Munoz, E; Pollastro, F; Taglialatela-Scafati, O, 2019) |
| "Non-alcoholic fatty liver disease (NAFLD) characterizes and predicts T2DM yet the relationship of coffee with this disorder remains unclear." | 1.42 | Associations of coffee consumption with markers of liver injury in the insulin resistance atherosclerosis study. ( Dickson, JC; Haffner, SM; Hamren, SJ; Hanley, AJ; Liese, AD; Lorenzo, C; Stiles, JK; Wagenknecht, LE; Watkins, SM, 2015) |
| "Caffeine displays significant antioxidant ability in protecting membranes against oxidative damage and can lower the risk of insulin resistance." | 1.40 | Caffeine intake improves fructose-induced hypertension and insulin resistance by enhancing central insulin signaling. ( Chen, BR; Cheng, PW; Cheng, WH; Ho, WY; Liou, JC; Liu, CP; Lu, PJ; Sun, GC; Tseng, CJ; Yeh, TC, 2014) |
| "Insulin sensitivity was assessed by means of the insulin tolerance test." | 1.39 | Chronic caffeine intake reverses age-induced insulin resistance in the rat: effect on skeletal muscle Glut4 transporters and AMPK activity. ( Conde, SV; Guarino, MP; Ribeiro, MJ; Sacramento, JF, 2013) |
| "The association of CC with nonalcoholic fatty liver disease (NAFLD) has not been established." | 1.38 | Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis. ( Calcagno, CJ; Harrison, SA; Jones, FJ; Molloy, JW; Torres, DM; Williams, CD, 2012) |
| "The treatment with caffeine in the rats fed the high-carbohydrate, high-fat diet decreased body fat and systolic blood pressure, improved glucose tolerance and insulin sensitivity, and attenuated cardiovascular and hepatic abnormalities, although the plasma lipid concentrations were further increased." | 1.38 | Caffeine attenuates metabolic syndrome in diet-induced obese rats. ( Brown, L; Kauter, K; Panchal, SK; Ward, LC; Wong, WY, 2012) |
| "Black espresso coffee in people with type 2 diabetes mellitus results in a marginally greater excursion of glucose during a following OGTT compared with water or decaffeinated coffee." | 1.38 | A cross-over study of the acute effects of espresso coffee on glucose tolerance and insulin sensitivity in people with type 2 diabetes mellitus. ( Carroll, RW; Downie, M; Krebs, JD; Parry-Strong, A; Weatherall, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.60) | 18.7374 |
| 1990's | 1 (1.30) | 18.2507 |
| 2000's | 19 (24.68) | 29.6817 |
| 2010's | 44 (57.14) | 24.3611 |
| 2020's | 11 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, J | 1 |
| Ahn, S | 2 |
| Kim, HJ | 1 |
| Lee, M | 1 |
| Kim, J | 1 |
| Jin, SH | 1 |
| Lee, E | 1 |
| Kim, G | 1 |
| Cheong, JH | 1 |
| Jacobson, KA | 1 |
| Jeong, LS | 1 |
| Noh, M | 1 |
| Srivastava, B | 1 |
| Sen, S | 1 |
| Bhakta, S | 1 |
| Sen, K | 1 |
| Kakiyama, G | 1 |
| Minowa, K | 1 |
| Rodriguez-Agudo, D | 1 |
| Martin, R | 1 |
| Takei, H | 1 |
| Mitamura, K | 1 |
| Ikegawa, S | 1 |
| Suzuki, M | 1 |
| Nittono, H | 1 |
| Fuchs, M | 1 |
| Heuman, DM | 1 |
| Zhou, H | 1 |
| Pandak, WM | 1 |
| Wu, Z | 1 |
| Yu, W | 1 |
| Ni, W | 1 |
| Teng, C | 1 |
| Ye, W | 1 |
| Yu, C | 1 |
| Zeng, Y | 1 |
| Alhadi, IA | 1 |
| Al Ansari, AM | 1 |
| AlSaleh, AFF | 1 |
| Alabbasi, AMA | 1 |
| Alshahrani, SH | 1 |
| Atia, YA | 1 |
| Badir, RA | 1 |
| Almalki, SG | 1 |
| Tayyib, NA | 1 |
| Shahab, S | 1 |
| Romero-Parra, RM | 1 |
| Abid, MK | 1 |
| Hussien, BM | 1 |
| Ramaiah, P | 1 |
| Cornelis, MC | 1 |
| Smith, HA | 1 |
| Hengist, A | 1 |
| Thomas, J | 1 |
| Walhin, JP | 1 |
| Heath, P | 1 |
| Perkin, O | 1 |
| Chen, YC | 1 |
| Gonzalez, JT | 1 |
| Betts, JA | 1 |
| Lee, S | 1 |
| Min, JY | 1 |
| Min, KB | 1 |
| Kotańska, M | 1 |
| Dziubina, A | 1 |
| Szafarz, M | 1 |
| Mika, K | 1 |
| Reguła, K | 1 |
| Bednarski, M | 1 |
| Zygmunt, M | 1 |
| Drabczyńska, A | 1 |
| Sapa, J | 1 |
| Kieć-Kononowicz, K | 1 |
| Velázquez, AM | 1 |
| Roglans, N | 1 |
| Bentanachs, R | 1 |
| Gené, M | 1 |
| Sala-Vila, A | 1 |
| Lázaro, I | 1 |
| Rodríguez-Morató, J | 1 |
| Sánchez, RM | 1 |
| Laguna, JC | 1 |
| Alegret, M | 1 |
| Mansour, A | 1 |
| Mohajeri-Tehrani, MR | 1 |
| Samadi, M | 1 |
| Qorbani, M | 1 |
| Merat, S | 1 |
| Adibi, H | 1 |
| Poustchi, H | 1 |
| Hekmatdoost, A | 1 |
| Fu, QY | 1 |
| Li, QS | 1 |
| Lin, XM | 1 |
| Qiao, RY | 1 |
| Yang, R | 1 |
| Li, XM | 1 |
| Dong, ZB | 1 |
| Xiang, LP | 1 |
| Zheng, XQ | 1 |
| Lu, JL | 1 |
| Yuan, CB | 1 |
| Ye, JH | 1 |
| Liang, YR | 1 |
| Dewar, L | 1 |
| Heuberger, R | 1 |
| Kou, H | 1 |
| Wang, GH | 1 |
| Pei, LG | 1 |
| Zhang, L | 1 |
| Shi, C | 1 |
| Guo, Y | 1 |
| Wu, DF | 1 |
| Wang, H | 1 |
| Liu, CW | 1 |
| Tsai, HC | 1 |
| Huang, CC | 1 |
| Tsai, CY | 1 |
| Su, YB | 1 |
| Lin, MW | 1 |
| Lee, KC | 1 |
| Hsieh, YC | 1 |
| Li, TH | 1 |
| Huang, SF | 1 |
| Yang, YY | 1 |
| Hou, MC | 1 |
| Lin, HC | 1 |
| Lee, FY | 1 |
| Lee, SD | 1 |
| Roshan, H | 1 |
| Nikpayam, O | 1 |
| Sedaghat, M | 1 |
| Sohrab, G | 1 |
| Cherniack, EP | 1 |
| Buslach, N | 1 |
| Lee, HF | 1 |
| Reis, CEG | 1 |
| Paiva, CLRDS | 1 |
| Amato, AA | 1 |
| Lofrano-Porto, A | 1 |
| Wassell, S | 1 |
| Bluck, LJC | 1 |
| Dórea, JG | 1 |
| da Costa, THM | 1 |
| Kawada, T | 1 |
| Daily, JW | 1 |
| Liu, M | 1 |
| Park, S | 2 |
| Chianese, G | 1 |
| Golin-Pacheco, SD | 1 |
| Taglialatela-Scafati, O | 1 |
| Collado, JA | 1 |
| Munoz, E | 1 |
| Appendino, G | 1 |
| Pollastro, F | 1 |
| Inoue, M | 1 |
| Tsugane, S | 1 |
| Emami, MR | 1 |
| Khorshidi, M | 1 |
| Zarezadeh, M | 1 |
| Safabakhsh, M | 1 |
| Rezagholizadeh, F | 1 |
| Alizadeh, S | 1 |
| Zheng, XX | 1 |
| Xu, YL | 1 |
| Li, SH | 1 |
| Hui, R | 1 |
| Wu, YJ | 1 |
| Huang, XH | 1 |
| Beaudoin, MS | 1 |
| Allen, B | 1 |
| Mazzetti, G | 1 |
| Sullivan, PJ | 1 |
| Graham, TE | 5 |
| Ohno, M | 1 |
| Shibata, C | 1 |
| Kishikawa, T | 1 |
| Yoshikawa, T | 1 |
| Takata, A | 1 |
| Kojima, K | 1 |
| Akanuma, M | 1 |
| Kang, YJ | 1 |
| Yoshida, H | 1 |
| Otsuka, M | 1 |
| Koike, K | 1 |
| Jarrar, SF | 1 |
| Obeid, OA | 1 |
| Lecoultre, V | 1 |
| Carrel, G | 1 |
| Egli, L | 1 |
| Binnert, C | 1 |
| Boss, A | 1 |
| MacMillan, EL | 1 |
| Kreis, R | 1 |
| Boesch, C | 1 |
| Darimont, C | 1 |
| Tappy, L | 1 |
| Yeh, TC | 1 |
| Liu, CP | 1 |
| Cheng, WH | 1 |
| Chen, BR | 1 |
| Lu, PJ | 1 |
| Cheng, PW | 1 |
| Ho, WY | 1 |
| Sun, GC | 1 |
| Liou, JC | 1 |
| Tseng, CJ | 1 |
| Cowan, TE | 1 |
| Palmnäs, MS | 1 |
| Yang, J | 1 |
| Bomhof, MR | 1 |
| Ardell, KL | 1 |
| Reimer, RA | 1 |
| Vogel, HJ | 1 |
| Shearer, J | 3 |
| Sacramento, JF | 2 |
| Ribeiro, MJ | 2 |
| Yubero, S | 1 |
| Melo, BF | 1 |
| Obeso, A | 1 |
| Guarino, MP | 3 |
| Gonzalez, C | 2 |
| Conde, SV | 3 |
| Dickson, JC | 1 |
| Liese, AD | 2 |
| Lorenzo, C | 1 |
| Haffner, SM | 2 |
| Watkins, SM | 1 |
| Hamren, SJ | 1 |
| Stiles, JK | 1 |
| Wagenknecht, LE | 2 |
| Hanley, AJ | 2 |
| Rakvaag, E | 1 |
| Dragsted, LO | 1 |
| Rocha, A | 1 |
| Bolin, AP | 1 |
| Cardoso, CA | 1 |
| Otton, R | 1 |
| Wise, LA | 1 |
| Laughlin-Tommaso, SK | 1 |
| Rasaei, B | 1 |
| Talib, RA | 1 |
| Noor, MI | 1 |
| Karandish, M | 1 |
| Karim, NA | 1 |
| Sarriá, B | 1 |
| Martínez-López, S | 1 |
| Sierra-Cinos, JL | 1 |
| García-Diz, L | 1 |
| Mateos, R | 1 |
| Bravo-Clemente, L | 1 |
| Nowak, C | 1 |
| Salihovic, S | 1 |
| Ganna, A | 1 |
| Brandmaier, S | 1 |
| Tukiainen, T | 1 |
| Broeckling, CD | 1 |
| Magnusson, PK | 1 |
| Prenni, JE | 1 |
| Wang-Sattler, R | 1 |
| Peters, A | 1 |
| Strauch, K | 1 |
| Meitinger, T | 1 |
| Giedraitis, V | 1 |
| Ärnlöv, J | 1 |
| Berne, C | 1 |
| Gieger, C | 1 |
| Ripatti, S | 1 |
| Lind, L | 1 |
| Pedersen, NL | 1 |
| Sundström, J | 1 |
| Ingelsson, E | 1 |
| Fall, T | 1 |
| Shi, X | 1 |
| Xue, W | 1 |
| Liang, S | 1 |
| Zhao, J | 1 |
| Zhang, X | 1 |
| Brown, CM | 1 |
| Dulloo, AG | 1 |
| Montani, JP | 1 |
| Tunnicliffe, JM | 1 |
| Moisey, LL | 1 |
| Robinson, LE | 2 |
| Dworzański, W | 1 |
| Opielak, G | 1 |
| Burdan, F | 1 |
| Tornai, I | 1 |
| Loopstra-Masters, RC | 1 |
| Laughon, SK | 1 |
| Powers, RW | 1 |
| Roberts, JM | 1 |
| Parana, S | 1 |
| Catov, J | 1 |
| Nunes da Silva, T | 1 |
| Mota Carmo, M | 1 |
| Monteiro, EC | 1 |
| Wedick, NM | 1 |
| Brennan, AM | 1 |
| Sun, Q | 1 |
| Hu, FB | 1 |
| Mantzoros, CS | 1 |
| van Dam, RM | 1 |
| Molloy, JW | 1 |
| Calcagno, CJ | 1 |
| Williams, CD | 1 |
| Jones, FJ | 1 |
| Torres, DM | 1 |
| Harrison, SA | 1 |
| Matsuda, Y | 1 |
| Kobayashi, M | 1 |
| Yamauchi, R | 1 |
| Ojika, M | 1 |
| Hiramitsu, M | 1 |
| Inoue, T | 1 |
| Katagiri, T | 1 |
| Murai, A | 1 |
| Horio, F | 1 |
| Ho, L | 1 |
| Varghese, M | 1 |
| Wang, J | 1 |
| Zhao, W | 1 |
| Chen, F | 1 |
| Knable, LA | 1 |
| Ferruzzi, M | 1 |
| Pasinetti, GM | 1 |
| Krebs, JD | 1 |
| Parry-Strong, A | 1 |
| Weatherall, M | 1 |
| Carroll, RW | 1 |
| Downie, M | 1 |
| Panchal, SK | 1 |
| Wong, WY | 1 |
| Kauter, K | 1 |
| Ward, LC | 1 |
| Brown, L | 1 |
| Ihm, SH | 1 |
| Jang, SW | 1 |
| Kim, OR | 1 |
| Chang, K | 1 |
| Oak, MH | 1 |
| Lee, JO | 1 |
| Lim, DY | 1 |
| Kim, JH | 1 |
| Whitehead, N | 1 |
| White, H | 1 |
| Richelsen, B | 2 |
| Petrie, HJ | 1 |
| Chown, SE | 1 |
| Belfie, LM | 1 |
| Duncan, AM | 1 |
| McLaren, DH | 2 |
| Conquer, JA | 1 |
| Savani, S | 1 |
| Battram, DS | 1 |
| Sathasivam, P | 1 |
| Belke, DD | 1 |
| Swanson, EA | 1 |
| Dillmann, WH | 1 |
| Ruhl, CE | 1 |
| Everhart, JE | 1 |
| Wold, LE | 1 |
| Dutta, K | 1 |
| Mason, MM | 1 |
| Ren, J | 1 |
| Cala, SE | 1 |
| Schwanke, ML | 1 |
| Davidoff, AJ | 1 |
| Sudano, I | 1 |
| Binggeli, C | 1 |
| Spieker, L | 1 |
| Lüscher, TF | 1 |
| Ruschitzka, F | 1 |
| Noll, G | 1 |
| Corti, R | 1 |
| Volcy, M | 1 |
| Tepper, SJ | 1 |
| Rapoport, AM | 1 |
| Sheftell, FD | 1 |
| Bigal, ME | 1 |
| Higdon, JV | 1 |
| Frei, B | 1 |
| Norager, CB | 1 |
| Jensen, MB | 1 |
| Weimann, A | 1 |
| Madsen, MR | 1 |
| Jang, JS | 1 |
| Hong, SM | 1 |
| Misra, T | 1 |
| Gilchrist, JS | 1 |
| Russell, JC | 1 |
| Pierce, GN | 1 |
| Shi, CL | 1 |
| Täljedal, IB | 1 |
| Nordin, A | 1 |
| Andersson, A | 1 |
| Keijzers, GB | 1 |
| De Galan, BE | 1 |
| Tack, CJ | 1 |
| Smits, P | 1 |
| Biaggioni, I | 1 |
| Davis, SN | 1 |
| Poulsen, PL | 1 |
| Møller, N | 1 |
| Schmitz, O | 1 |
| Mogensen, CE | 1 |
| Jéquier, E | 1 |
| Pedersen, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Green Coffee Supplementation on Inflammatory Biomarkers in Obese Patients With Metabolic Syndrome[NCT05688917] | 160 participants (Actual) | Interventional | 2020-09-03 | Completed | |||
| Effects of Coffees With Various Compositions of Antioxidants on Hepatic Steatosis Induced by a High Fructose, Hypercaloric Diet[NCT00827450] | 13 participants (Actual) | Interventional | 2009-02-28 | Completed | |||
| Effects of Caffeinated and Decaffeinated Coffee on Body Weight and Glucose Tolerance[NCT00305097] | 45 participants (Actual) | Interventional | 2006-05-31 | Completed | |||
| A Pilot, Randomized, Double-blind, Placebo-controlled, Parallel Design Study to Evaluate the Effectiveness and Safety of an Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health Among [NCT05170113] | 79 participants (Actual) | Interventional | 2021-11-02 | Completed | |||
| Neuroplastic Alterations of the Motor Cortex by Caffeine: Differences Between Caffeine and Non-caffeine Users and Influence of Vigilance During Stimulation[NCT04011670] | 30 participants (Actual) | Interventional | 2019-07-15 | Completed | |||
| Effect of Coffee and Tea Consumption on Adolescent Weight Control - a Randomized Clinical Trial[NCT05181176] | 63 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | |||
| Cortical Excitability Changes on the Sensorimotor Cortex Induced by Caffeine Consumption: A TMS Study[NCT03720665] | 30 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| The Effect of Caffeine as Endurance Enhancing Drug in the Elderly Following Eight Hour Abstinence From Caffeine Containing Drinks and Foods[NCT01048515] | Phase 4 | 30 participants (Actual) | Interventional | 2005-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 reviews available for caffeine and Insulin Resistance
| Article | Year |
|---|---|
Systematic review of the effect of caffeine therapy effect on cardiometabolic markers in rat models of the metabolic syndrome.
Topics: Animals; Caffeine; Hypertension; Insulin Resistance; Metabolic Syndrome; Obesity; Rats | 2023 |
Antidiabetic Effects of Tea.
Topics: Animals; Caffeine; Camellia sinensis; Catechin; Diabetes Mellitus; Diabetes Mellitus, Experimental; | 2017 |
The effect of acute caffeine intake on insulin sensitivity and glycemic control in people with diabetes.
Topics: Adult; Blood Glucose; Caffeine; Diabetes Mellitus; Female; Humans; Insulin Resistance; Male; Middle | 2017 |
The Potential Effects of Caffeinated Beverages on Insulin Sensitivity.
Topics: Animals; Beverages; Blood Glucose; Cacao; Caffeine; Chocolate; Coffee; Diabetes Mellitus; Diet; Food | 2018 |
Coffee Drinking and Reduced Risk of Liver Cancer: Update on Epidemiological Findings and Potential Mechanisms.
Topics: Antioxidants; Caffeine; Cardiovascular Diseases; Chlorogenic Acid; Coffee; Diabetes Mellitus; Drinki | 2019 |
Acute effects of caffeine ingestion on glycemic indices: A systematic review and meta-analysis of clinical trials.
Topics: Animals; Blood Glucose; Caffeine; Clinical Trials as Topic; Glycemic Index; Humans; Insulin Resistan | 2019 |
Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials.
Topics: Adult; Blood Glucose; Caffeine; Camellia sinensis; Catechin; Glycated Hemoglobin; Humans; Hyperglyce | 2013 |
Performance effects and metabolic consequences of caffeine and caffeinated energy drink consumption on glucose disposal.
Topics: Athletic Performance; Blood Glucose; Caffeine; Central Nervous System Stimulants; Energy Drinks; Exe | 2014 |
Epidemiology of Uterine Fibroids: From Menarche to Menopause.
Topics: Age Distribution; Age Factors; Alcohol Drinking; Black People; Caffeine; Diabetes Mellitus; Diet; Fe | 2016 |
Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study.
Topics: Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Caffeine; Diabetes Mellitus, Type 2; Fatty Aci | 2016 |
Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: a systematic review and meta-analysis.
Topics: Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Ran | 2016 |
Sugary drinks in the pathogenesis of obesity and cardiovascular diseases.
Topics: Adiposity; Animals; Beverages; Caffeine; Cardiovascular Diseases; Dietary Sucrose; Dogs; Fructose; H | 2008 |
Coffee, glucose homeostasis, and insulin resistance: physiological mechanisms and mediators.
Topics: Animals; Antioxidants; Blood Glucose; Caffeine; Central Nervous System Stimulants; Coffee; Diabetes | 2008 |
[Role of environmental factors in the etiology of hepatocellular carcinoma].
Topics: Aflatoxins; Alcohol Drinking; Antioxidants; Caffeine; Carcinoma, Hepatocellular; Coffee; Contracepti | 2010 |
Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus.
Topics: Beverages; Blood Glucose; Caffeine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, | 2013 |
Cardiovascular effects of coffee: is it a risk factor?
Topics: Blood Glucose; Caffeine; Cardiovascular System; Coffee; Cooking; Diabetes Mellitus, Type 1; Drinking | 2005 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Caffeine: a cause of insulin resistance?
Topics: Caffeine; Central Nervous System Stimulants; Humans; Insulin Resistance | 2002 |
Energy utilization in human obesity.
Topics: Basal Metabolism; Body Temperature Regulation; Caffeine; Cold Temperature; Eating; Energy Metabolism | 1987 |
Insulin receptor- and nonreceptor-controlled cellular substrate processing. A review of clinical studies in the isolated human adipocyte model.
Topics: 3-O-Methylglucose; Adipose Tissue; Biological Transport; Blood Cells; Caffeine; Cells, Cultured; Dia | 1985 |
15 trials available for caffeine and Insulin Resistance
| Article | Year |
|---|---|
Glucose control upon waking is unaffected by hourly sleep fragmentation during the night, but is impaired by morning caffeinated coffee.
Topics: Blood Glucose; Caffeine; Coffee; Cross-Over Studies; Female; Genotype; Glucose Tolerance Test; Glyce | 2020 |
Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-c
Topics: Caffeine; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Met | 2021 |
Effects of green coffee extract supplementation on anthropometric indices, glycaemic control, blood pressure, lipid profile, insulin resistance and appetite in patients with the metabolic syndrome: a randomised clinical trial.
Topics: Adult; Aged; Appetite; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Caffeine; Coffea | 2018 |
Decaffeinated coffee improves insulin sensitivity in healthy men.
Topics: Adult; Blood Glucose; Caffeine; Coffee; Cross-Over Studies; Diabetes Mellitus, Type 2; Glucose Toler | 2018 |
Caffeine ingestion impairs insulin sensitivity in a dose-dependent manner in both men and women.
Topics: Adult; Blood Glucose; C-Peptide; Caffeine; Cross-Over Studies; Dose-Response Relationship, Drug; Dou | 2013 |
Coffee consumption attenuates short-term fructose-induced liver insulin resistance in healthy men.
Topics: Absorptiometry, Photon; Adolescent; Adult; Body Composition; Body Weight; Caffeine; Chlorogenic Acid | 2014 |
Acute effects of light and dark roasted coffee on glucose tolerance: a randomized, controlled crossover trial in healthy volunteers.
Topics: Adolescent; Adult; Aged; Area Under Curve; Blood Glucose; Body Mass Index; Caffeine; Chlorogenic Aci | 2016 |
Simultaneous coffee caffeine intake and sleep deprivation alter glucose homeostasis in Iranian men: a randomized crossover trial.
Topics: Adult; Blood Glucose; Caffeine; Coffee; Cross-Over Studies; Fasting; Glucose Tolerance Test; Homeost | 2016 |
Regularly consuming a green/roasted coffee blend reduces the risk of metabolic syndrome.
Topics: Adipokines; Adolescent; Adult; Blood Glucose; Blood Pressure; Body Composition; Caffeine; Coffea; Co | 2018 |
Consumption of caffeinated coffee and a high carbohydrate meal affects postprandial metabolism of a subsequent oral glucose tolerance test in young, healthy males.
Topics: Adult; Blood Glucose; C-Peptide; Caffeine; Coffee; Cross-Over Studies; Dietary Carbohydrates; Fastin | 2010 |
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial.
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Beverages; Blood Glucose; Caffeine; Coffee; Diabetes Me | 2011 |
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial.
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Beverages; Blood Glucose; Caffeine; Coffee; Diabetes Me | 2011 |
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial.
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Beverages; Blood Glucose; Caffeine; Coffee; Diabetes Me | 2011 |
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial.
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Beverages; Blood Glucose; Caffeine; Coffee; Diabetes Me | 2011 |
Caffeine ingestion increases the insulin response to an oral-glucose-tolerance test in obese men before and after weight loss.
Topics: Administration, Oral; Adult; Area Under Curve; Blood Glucose; C-Peptide; Caffeine; Central Nervous S | 2004 |
Caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetes.
Topics: Adult; Area Under Curve; Blood Glucose; Caffeine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Doub | 2004 |
Metabolic effects of caffeine ingestion and physical work in 75-year old citizens. A randomized, double-blind, placebo-controlled, cross-over study.
Topics: Administration, Oral; Aged; Blood Glucose; Caffeine; Calcium; Cross-Over Studies; Double-Blind Metho | 2006 |
Caffeine can decrease insulin sensitivity in humans.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Dipyridamole; Double-Blind Method; Epinephrine; | 2002 |
42 other studies available for caffeine and Insulin Resistance
| Article | Year |
|---|---|
Polypharmacology of N
Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; | 2017 |
Effect of caffeine on the possible amelioration of diabetic neuropathy: A spectroscopic study.
Topics: Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Insulin; Insulin | 2022 |
Coffee modulates insulin-hepatocyte nuclear factor-4α-Cyp7b1 pathway and reduces oxysterol-driven liver toxicity in a nonalcoholic fatty liver disease mouse model.
Topics: Animals; Caffeine; Cholesterol; Coffee; Cytochrome P450 Family 7; Disease Models, Animal; Hepatitis; | 2022 |
Improvement of obesity by Liupao tea is through the IRS-1/PI3K/AKT/GLUT4 signaling pathway according to network pharmacology and experimental verification.
Topics: 3T3-L1 Cells; Animals; Caffeine; CCAAT-Enhancer-Binding Protein-alpha; Humans; Insulin; Insulin Rece | 2023 |
Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals.
Topics: Body Mass Index; Caffeine; Cross-Sectional Studies; Eating; Humans; Insulin; Insulin Resistance; Obe | 2023 |
Coffee and type 2 diabetes: time to consider alternative mechanisms?
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Risk Factors | 2020 |
Caffeine and Caffeine Metabolites in Relation to Insulin Resistance and Beta Cell Function in U.S. Adults.
Topics: Adult; Aged; Blood Glucose; Caffeine; Female; Humans; Insulin Resistance; Insulin-Secreting Cells; M | 2020 |
KD-64-A new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist-Caffeine does not reduce diet-induced obesity in mice.
Topics: Adenosine A2 Receptor Antagonists; Animals; Anti-Inflammatory Agents; Body Weight; Caffeine; Capilla | 2020 |
Effects of a Low Dose of Caffeine Alone or as Part of a Green Coffee Extract, in a Rat Dietary Model of Lean Non-Alcoholic Fatty Liver Disease without Inflammation.
Topics: Animals; Caffeine; Coffee; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal | 2020 |
Effects of prenatal caffeine exposure on glucose homeostasis of adult offspring rats.
Topics: Animals; Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Female; Fetal Growth Retardation; Gene | 2017 |
Effects and mechanisms of caffeine to improve immunological and metabolic abnormalities in diet-induced obese rats.
Topics: Adiposity; Animals; Caffeine; Cells, Cultured; Diet, High-Fat; Fatty Liver; Immune System Diseases; | 2018 |
Decaffeinated green coffee bean extract and the components of the metabolic syndrome.
Topics: Beverages; Body Mass Index; Body Weight; Caffeine; Coffee; Cross-Over Studies; Cross-Sectional Studi | 2018 |
High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults.
Topics: Adult; Blood Glucose; Caffeine; Central Nervous System Stimulants; Coffee; Female; Gene-Environment | 2019 |
Bioactive triterpenoids from the caffeine-rich plants guayusa and maté.
Topics: Caffeine; Diabetes Mellitus; Ilex guayusa; Ilex paraguariensis; Insulin Resistance; Metabolic Syndro | 2019 |
The flavonoid apigenin improves glucose tolerance through inhibition of microRNA maturation in miRNA103 transgenic mice.
Topics: Animals; Apigenin; Caffeine; Glucose; Glucose Tolerance Test; Insulin Resistance; Liver; MAP Kinase | 2013 |
Timing of caffeine ingestion alters postprandial metabolism in rats.
Topics: Animals; Blood Glucose; Caffeine; Carbohydrate Metabolism; Glycogen; Insulin; Insulin Resistance; Ma | 2014 |
Caffeine intake improves fructose-induced hypertension and insulin resistance by enhancing central insulin signaling.
Topics: Animals; Blood Pressure; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Fructo | 2014 |
Chronic coffee consumption in the diet-induced obese rat: impact on gut microbiota and serum metabolomics.
Topics: Animals; Blood Glucose; Body Composition; Caffeine; Coffee; Diet, High-Fat; Gastrointestinal Tract; | 2014 |
Disclosing caffeine action on insulin sensitivity: effects on rat skeletal muscle.
Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Female; Insulin Resistance; Male; Muscle, Skele | 2015 |
Associations of coffee consumption with markers of liver injury in the insulin resistance atherosclerosis study.
Topics: Alanine Transaminase; alpha-2-HS-Glycoprotein; Aspartate Aminotransferases; Biomarkers; Caffeine; Co | 2015 |
Green tea extract activates AMPK and ameliorates white adipose tissue metabolic dysfunction induced by obesity.
Topics: Adipose Tissue, White; Alanine Transaminase; AMP-Activated Protein Kinases; Animals; Antioxidants; A | 2016 |
[Side effects of caffeine].
Topics: Abortion, Spontaneous; Arteries; Caffeine; Cholesterol; Coronary Disease; Cytochrome P-450 CYP1A2; C | 2009 |
Associations between the intake of caffeinated and decaffeinated coffee and measures of insulin sensitivity and beta cell function.
Topics: Adult; Aged; Blood Glucose; Caffeine; Coffee; Cross-Sectional Studies; Female; Humans; Insulin Resis | 2011 |
Caffeine and insulin resistance in pregnancy.
Topics: Birth Weight; Caffeine; Female; Homeostasis; Humans; Infant, Newborn; Insulin Resistance; Male; Preg | 2011 |
Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats.
Topics: Adiposity; Adrenergic Antagonists; Animals; Body Weight; Caffeine; Carbazoles; Carvedilol; Catechola | 2012 |
Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis.
Topics: Age Factors; Alanine Transaminase; Body Mass Index; Caffeine; Coffee; Fatty Liver; Female; Glycated | 2012 |
Coffee and caffeine improve insulin sensitivity and glucose tolerance in C57BL/6J mice fed a high-fat diet.
Topics: Adipokines; Adipose Tissue; Animals; Blood Glucose; Caffeine; Coffee; Diet, High-Fat; Eating; Fatty | 2011 |
Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice.
Topics: Animals; Beverages; Blood Glucose; Brain; Caffeine; Chlorogenic Acid; Coffee; Diabetes Mellitus, Typ | 2012 |
A cross-over study of the acute effects of espresso coffee on glucose tolerance and insulin sensitivity in people with type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Caffeine; Central Nervous System Stimulants; Coffee; Cross-Over Studies; | 2012 |
Caffeine attenuates metabolic syndrome in diet-induced obese rats.
Topics: Adipose Tissue; Animals; Blood Pressure; Caffeine; Cardiovascular System; Diet, High-Fat; Dietary Ca | 2012 |
Decaffeinated green tea extract improves hypertension and insulin resistance in a rat model of metabolic syndrome.
Topics: Animals; Antihypertensive Agents; Antioxidants; Aorta, Thoracic; Blood Glucose; Blood Pressure; Caff | 2012 |
Chronic caffeine intake reverses age-induced insulin resistance in the rat: effect on skeletal muscle Glut4 transporters and AMPK activity.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Blood Glucose; Blotting, Western; Caffeine; Diabetes | 2013 |
[Letigen, insulin resistance and treatment of obesity].
Topics: Appetite Depressants; Caffeine; Ephedrine; Humans; Insulin Resistance; Obesity | 2002 |
[Letigen, insulin resistance and treatment of obesity--again].
Topics: Appetite Depressants; Caffeine; Central Nervous System Stimulants; Ephedrine; Humans; Insulin Resist | 2002 |
Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Diabetes Mellitus, Type 2; Insulin Resista | 2004 |
Coffee and caffeine consumption reduce the risk of elevated serum alanine aminotransferase activity in the United States.
Topics: Alanine Transaminase; Alcohol Drinking; Caffeine; Coffee; Female; Glucose Metabolism Disorders; Hepa | 2005 |
Impaired SERCA function contributes to cardiomyocyte dysfunction in insulin resistant rats.
Topics: Animals; Caffeine; Calcium Signaling; Calcium-Transporting ATPases; Insulin Resistance; Ion Exchange | 2005 |
Botulinum toxin A for the treatment of greater occipital neuralgia and trigeminal neuralgia: a case report with pathophysiological considerations.
Topics: Acetaminophen; Adult; Analgesics; Anxiety; Aspirin; Botulinum Toxins, Type A; Caffeine; Colitis, Ulc | 2006 |
Long-term consumption of caffeine improves glucose homeostasis by enhancing insulinotropic action through islet insulin/insulin-like growth factor 1 signaling in diabetic rats.
Topics: Animals; Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Glucokinase; Glucose Clamp Technique; G | 2007 |
Cardiac myofibrillar and sarcoplasmic reticulum function are not depressed in insulin-resistant JCR:LA-cp rats.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Cardiovascular Diseases; Diabetes Mellitus | 1999 |
Human islets transplanted to nude mice: in vitro insulin release from retrieved grafts.
Topics: Acetylcholine; Adult; Animals; Arginine; Caffeine; Humans; Insulin; Insulin Resistance; Insulin Secr | 2000 |
[Coffee and diabetes--something to be really concerned about?].
Topics: Caffeine; Cardiovascular Diseases; Coffee; Diabetes Mellitus, Type 2; Feeding Behavior; Humans; Insu | 2002 |