Page last updated: 2024-10-24

caffeine and Infantile Respiratory Distress Syndrome

caffeine has been researched along with Infantile Respiratory Distress Syndrome in 21 studies

Research Excerpts

ExcerptRelevanceReference
"Apnea of prematurity, which is prevalent among infants born at less than 34 weeks gestation, is treated with caffeine, theophylline, or aminophylline."7.81Ampakines enhance weak endogenous respiratory drive and alleviate apnea in perinatal rats. ( Ding, X; Greer, JJ; Ren, J, 2015)
"Caffeine is commonly used to prevent or treat apnea in preterm neonates."5.51Effect of Prophylactic Caffeine on Noninvasive Respiratory Support in Preterm Neonates Weighing 1250-2000 g: A Randomized Controlled Trial. ( Armanian, AM; Feizi, A; Iranpour, R; Miladi, N, 2022)
"Early caffeine treatment can reduce the need for assisted ventilation in preterm infants with RDS, help with early extubation and ventilator weaning, reduce the oxygen time in the late stage, reduce the incidence of VAP, and prevent the development of apnea after extubation."5.22[Effect of early caffeine treatment on the need for respirator therapy in preterm infants with respiratory distress syndrome]. ( Duan, YH; Han, JT; Su, P; Wei, QZ; Zhang, X, 2016)
"Caffeine is one of the most commonly prescribed medications in preterm neonates and is widely used to treat or prevent apnea of prematurity."4.93The Role of Caffeine in Noninvasive Respiratory Support. ( Dobson, NR; Patel, RM, 2016)
"Apnea of prematurity, which is prevalent among infants born at less than 34 weeks gestation, is treated with caffeine, theophylline, or aminophylline."3.81Ampakines enhance weak endogenous respiratory drive and alleviate apnea in perinatal rats. ( Ding, X; Greer, JJ; Ren, J, 2015)
"The treatment of neonatal apnea and bradycardia with methylated xanthines--theophylline and caffeine--is generally accepted."3.68[Effect of methylxanthines on periodic respiration and acid gastroesophageal reflux in newborn infants]. ( Heimann, G; Koch, G; Skopnik, H, 1990)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's3 (14.29)18.2507
2000's3 (14.29)29.6817
2010's9 (42.86)24.3611
2020's4 (19.05)2.80

Authors

AuthorsStudies
Li, XL1
Cai, YJ1
Zhang, Z1
Li, J1
Chen, XW1
Song, YY1
Zhou, W1
Iranpour, R1
Armanian, AM1
Miladi, N1
Feizi, A1
Sahoo, S1
Behura, SS1
Wasiq, MA1
Nayak, MK1
Mishra, A1
Panda, SK1
Ines, F1
Hutson, S1
Coughlin, K1
Hopper, A1
Banerji, A1
Uy, C1
Finer, N1
Rich, W1
Morales, A1
Steen, J1
Katheria, AC1
Picarillo, AP1
Carlo, W1
Borszewska-Kornacka, MK1
Hożejowski, R1
Rutkowska, M1
Lauterbach, R1
Martin, RJ1
Fanaroff, AA1
Ren, J1
Ding, X1
Greer, JJ1
Kribs, A1
Hummler, H1
Vento, G1
Pastorino, R1
Boni, L1
Cota, F1
Carnielli, V1
Cools, F1
Dani, C1
Mosca, F1
Pillow, J1
Polglase, G1
Tagliabue, P1
van Kaam, AH1
Ventura, ML1
Tana, M1
Tirone, C1
Aurilia, C1
Lio, A1
Ricci, C1
Gambacorta, A1
Consigli, C1
D'Onofrio, D1
Gizzi, C1
Massenzi, L1
Cardilli, V1
Casati, A1
Bottino, R1
Pontiggia, F1
Ciarmoli, E1
Martinelli, S1
Ilardi, L1
Colnaghi, M1
Matassa, PG1
Vendettuoli, V1
Villani, P1
Fusco, F1
Gazzolo, D1
Ricotti, A1
Ferrero, F1
Stasi, I1
Magaldi, R1
Maffei, G1
Presta, G1
Perniola, R1
Messina, F1
Montesano, G1
Poggi, C1
Giordano, L1
Roma, E1
Grassia, C1
Ausanio, G1
Sandri, F1
Mescoli, G1
Giura, F1
Garani, G1
Solinas, A1
Lucente, M1
Nigro, G1
Del Vecchio, A1
Petrillo, F1
Orfeo, L1
Grappone, L1
Quartulli, L1
Scorrano, A1
Messner, H1
Staffler, A1
Gargano, G1
Balestri, E1
Nobile, S1
Cacace, C1
Meli, V1
Dallaglio, S1
Pasqua, B1
Mattia, L1
Gitto, E1
Vitaliti, M1
Re, MP1
Vedovato, S1
Grison, A1
Berardi, A1
Torcetta, F1
Guidotti, I1
di Fabio, S1
Maranella, E1
Mondello, I1
Visentin, S1
Tormena, F1
Dobson, NR1
Patel, RM1
Wei, QZ1
Su, P1
Han, JT1
Zhang, X1
Duan, YH1
Kassim, Z1
Greenough, A2
Rafferty, GF1
Verder, H1
Bohlin, K1
Kamper, J1
Lindwall, R1
Jonsson, B1
Sant'Anna, GM1
Keszler, M1
Yoder, B1
Thomson, M1
Coalson, J1
Streissguth, AP1
Barr, HM1
Martin, DC1
Laubscher, B1
Dimitriou, G1
Mehta, PN1
Panitch, HB1
Wolfson, MR1
Shaffer, TH1
Skopnik, H1
Koch, G1
Heimann, G1
Boda, D1
Németh, I1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Randomized Trial of Preterm Infants Receiving Caffeine and Less Invasive Surfactant Administration Compared to Caffeine and Early Continuous Positive Airway Pressure (CaLI Trial)[NCT04209946]180 participants (Actual)Interventional2020-01-22Active, not recruiting
"Efficacy of a New Technique -IN-REC-SUR-E- in Preterm Neonates With Respiratory Distress Syndrome During Non Invasive Ventilation: a Randomized Controlled Trial"[NCT02482766]206 participants (Actual)Interventional2015-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for caffeine and Infantile Respiratory Distress Syndrome

ArticleYear
Using Quality Improvement Tools to Reduce Chronic Lung Disease.
    Clinics in perinatology, 2017, Volume: 44, Issue:3

    Topics: Adrenal Cortex Hormones; Bronchopulmonary Dysplasia; Caffeine; Chronic Disease; Continuous Positive

2017
The preterm lung and airway: past, present, and future.
    Pediatrics and neonatology, 2013, Volume: 54, Issue:4

    Topics: Adrenal Cortex Hormones; Bronchopulmonary Dysplasia; Caffeine; Combined Modality Therapy; Female; Fo

2013
Ancillary therapies to enhance success of non-invasive modes of respiratory support - Approaches to delivery room use of surfactant and caffeine?
    Seminars in fetal & neonatal medicine, 2016, Volume: 21, Issue:3

    Topics: Caffeine; Delivery Rooms; Humans; Infant, Newborn; Infant, Premature; Noninvasive Ventilation; Pulmo

2016
The Role of Caffeine in Noninvasive Respiratory Support.
    Clinics in perinatology, 2016, Volume: 43, Issue:4

    Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newb

2016
Nasal CPAP and surfactant for treatment of respiratory distress syndrome and prevention of bronchopulmonary dysplasia.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:9

    Topics: Apnea; Bronchopulmonary Dysplasia; Caffeine; Central Nervous System Stimulants; Citrates; Combined M

2009
Weaning infants from mechanical ventilation.
    Clinics in perinatology, 2012, Volume: 39, Issue:3

    Topics: Adrenal Cortex Hormones; Airway Extubation; Autonomic Nervous System; Caffeine; Diuretics; Humans; I

2012

Trials

7 trials available for caffeine and Infantile Respiratory Distress Syndrome

ArticleYear
Effect of different maintenance doses of caffeine citrate on ventilator weaning in very preterm infants with respiratory distress syndrome: a prospective randomized controlled trial.
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2021, Nov-15, Volume: 23, Issue:11

    Topics: Caffeine; Citrates; Humans; Infant; Infant, Newborn; Infant, Premature; Prospective Studies; Respira

2021
Effect of Prophylactic Caffeine on Noninvasive Respiratory Support in Preterm Neonates Weighing 1250-2000 g: A Randomized Controlled Trial.
    Archives of Iranian medicine, 2022, 02-01, Volume: 25, Issue:2

    Topics: Apnea; Caffeine; Continuous Positive Airway Pressure; Humans; Infant; Infant, Newborn; Infant, Prema

2022
Respiratory Outcome of Delivery Room Caffeine in Preterm Neonates-A Pilot, Randomized, Controlled Trial.
    Indian journal of pediatrics, 2023, Volume: 90, Issue:1

    Topics: Caffeine; Delivery Rooms; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Pregn

2023
Multicentre, randomised trial of preterm infants receiving caffeine and less invasive surfactant administration compared with caffeine and early continuous positive airway pressure (CaLI trial): study protocol.
    BMJ open, 2021, 01-22, Volume: 11, Issue:1

    Topics: Caffeine; Continuous Positive Airway Pressure; Humans; Infant; Infant, Newborn; Infant, Premature; M

2021
Efficacy of a new technique - INtubate-RECruit-SURfactant-Extubate - "IN-REC-SUR-E" - in preterm neonates with respiratory distress syndrome: study protocol for a randomized controlled trial.
    Trials, 2016, 08-18, Volume: 17

    Topics: Airway Extubation; Biological Products; Caffeine; Central Nervous System Stimulants; Citrates; Conti

2016
[Effect of early caffeine treatment on the need for respirator therapy in preterm infants with respiratory distress syndrome].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2016, Volume: 18, Issue:12

    Topics: Apnea; Caffeine; Female; Humans; Infant; Infant, Newborn; Male; Prospective Studies; Respiratory Dis

2016
Comparative effects of theophylline and caffeine on respiratory function of prematurely born infants.
    Early human development, 1998, Jan-09, Volume: 50, Issue:2

    Topics: Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant,

1998

Other Studies

8 other studies available for caffeine and Infantile Respiratory Distress Syndrome

ArticleYear
Shifting the boundaries for early caffeine initiation in neonatal practice: Results of a prospective, multicenter study on very preterm infants with respiratory distress syndrome.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Bronchopulmonary Dysplasia; Caffeine; Humans; Infant, Newborn; Infant, Premature; Prospective Studie

2017
Ampakines enhance weak endogenous respiratory drive and alleviate apnea in perinatal rats.
    American journal of respiratory and critical care medicine, 2015, Mar-15, Volume: 191, Issue:6

    Topics: Analgesics, Opioid; Animals; Animals, Newborn; Apnea; Brain Stem; Caffeine; Disease Models, Animal;

2015
Effect of caffeine on respiratory muscle strength and lung function in prematurely born, ventilated infants.
    European journal of pediatrics, 2009, Volume: 168, Issue:12

    Topics: Caffeine; Central Nervous System Stimulants; Functional Residual Capacity; Humans; Infant, Newborn;

2009
Lung function in immature baboons with respiratory distress syndrome receiving early caffeine therapy: a pilot study.
    Acta paediatrica (Oslo, Norway : 1992), 2005, Volume: 94, Issue:1

    Topics: Animals; Animals, Newborn; Biological Products; Bronchodilator Agents; Caffeine; Citrates; Continuou

2005
Offspring effects and pregnancy complications related to self-reported maternal alcohol use.
    Developmental pharmacology and therapeutics, 1982, Volume: 5, Issue:1-2

    Topics: Abnormalities, Drug-Induced; Alcohol Drinking; Apgar Score; Caffeine; Female; Fetus; Heart Rate; Hum

1982
Dissociation between the effects of theophylline and caffeine on premature airway smooth muscles.
    Pediatric research, 1991, Volume: 29, Issue:5

    Topics: Acetylcholine; Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Female; Humans; Infant,

1991
[Effect of methylxanthines on periodic respiration and acid gastroesophageal reflux in newborn infants].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1990, Volume: 138, Issue:3

    Topics: Bradycardia; Caffeine; Citrates; Drug Combinations; Drug Therapy, Combination; Gastric Acidity Deter

1990
Measurement of urinary caffeine metabolites reflecting the "in vivo" xanthine oxidase activity in premature infants with RDS and in hypoxic states of children.
    Biomedica biochimica acta, 1989, Volume: 48, Issue:2-3

    Topics: Biomarkers; Caffeine; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Respiratory Distress Synd

1989