caffeine has been researched along with Hypoxia-Ischemia, Brain in 18 studies
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Caffeine was administered for 3 days and/or PBM for 5 days following HIE." | 5.91 | Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model. ( Beutner, G; Brophy, PD; Dahlstrom, JE; Groves, AM; Johnston, CJ; Kent, AL; Koina, M; Marples, B; O'Reilly, M; Porter, G, 2023) |
| "Caffeine-treated and -untreated pups underwent the Vannucci procedure (unilateral carotid ligation, global hypoxia) on P2." | 5.56 | Caffeine Restores Background EEG Activity Independent of Infarct Reduction after Neonatal Hypoxic Ischemic Brain Injury. ( Gonzalez, F; McQuillen, PS; Sun, H, 2020) |
| " Caffeine can ameliorate hypoxia-ischemia-induced brain WMD; however, its neuroprotective effect and mechanism against hypoxic-ischemic WMD remain unclear." | 4.12 | Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization. ( Fu, J; Liu, N; Xue, X; Yang, L; Yu, X; Zhang, Y, 2022) |
| "When asked to address the above question, findings that appeared to be among the most relevant included (1) interventions in the delivery room directed at supporting the physiological transition from intrauterine to extrauterine life rather than actively intervening in it; (2) recent data suggesting that keeping extremely low-gestational age neonates at a pulse oximeter saturation (SpO(2)) of 91-95% would increase their chances of survival compared with aiming for lower SpO(2) values; (3) using caffeine citrate in infants <1250 g with apnoea of prematurity improves neurodevelopmental outcome; (4) injecting antivascular epithelial growth factor into the vitreous seems to be an effective treatment for retinopathy of prematurity and (5) moderate hypothermia for perinatal hypoxic-ischaemic encephalopathy increases the likelihood of survival without neurological impairment." | 3.79 | What are the main research findings during the last 5 years that have changed my approach to clinical practice? ( Poets, CF, 2013) |
| "Caffeine treated animals performed worse on open field test compared to the controls (SDM -1." | 2.82 | The effects of caffeine following hypoxic-ischemic encephalopathy: A systematic review of animal studies. ( Bruschettini, M; Moreira, A; Mustafa, S; Pizarro, AB; Romantsik, O, 2022) |
| "Adenosine levels increase rapidly with tissue hypoxia and inflammation." | 2.47 | Adverse and protective influences of adenosine on the newborn and embryo: implications for preterm white matter injury and embryo protection. ( Rivkees, SA; Wendler, CC, 2011) |
| "Caffeine was administered for 3 days and/or PBM for 5 days following HIE." | 1.91 | Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model. ( Beutner, G; Brophy, PD; Dahlstrom, JE; Groves, AM; Johnston, CJ; Kent, AL; Koina, M; Marples, B; O'Reilly, M; Porter, G, 2023) |
| "Caffeine, which is a competitive inhibitor of adenosine receptors, is commonly used as treatment for preterm apnoea in clinical settings." | 1.56 | Defining a Time Window for Neuroprotection and Glia Modulation by Caffeine After Neonatal Hypoxia-Ischaemia. ( Ådén, U; Blomgren, K; Bocchetta, E; Di Martino, E; Harris, RA; Mukai, T; Tsuji, S, 2020) |
| "Caffeine-treated and -untreated pups underwent the Vannucci procedure (unilateral carotid ligation, global hypoxia) on P2." | 1.56 | Caffeine Restores Background EEG Activity Independent of Infarct Reduction after Neonatal Hypoxic Ischemic Brain Injury. ( Gonzalez, F; McQuillen, PS; Sun, H, 2020) |
| "Caffeine is a respiratory stimulant used during removal of infants from ventilation but has shown surprising long-term benefits, leading to consideration as a therapy for HI of prematurity." | 1.48 | Behavioral and neuroanatomical outcomes in a rat model of preterm hypoxic-ischemic brain Injury: Effects of caffeine and hypothermia. ( Fitch, RH; Potter, M; Rosenkrantz, T, 2018) |
| "Caffeine treatment significantly improves outcome when compared to phosphate buffered saline." | 1.46 | Single Dose Caffeine Protects the Neonatal Mouse Brain against Hypoxia Ischemia. ( Ådén, U; Fredholm, BB; Urmaliya, V; Winerdal, M; Winerdal, ME; Winqvist, O, 2017) |
| "Caffeine citrate (20 mg/kg) was injected intraperitoneally before hypoxia ischemia (HI) and immediately, 24 hours, 48 hours and 72 hours after HI." | 1.42 | [Effects of caffeine citrate on myelin basic protein in neonatal rats with hypoxic-ischemic brain damage]. ( Cheng, HQ; Guo, JJ; Wang, CH; Xu, FL; Zhang, YH, 2015) |
| "Caffeine displays a broad array of actions on the brain." | 1.40 | Effects of caffeine on neuronal apoptosis in neonatal hypoxic-ischemic brain injury. ( Daglioglu, YK; Erdogan, S; Kilicdag, H; Zorludemir, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 9 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Starr, MC | 1 |
| Charlton, JR | 1 |
| Guillet, R | 1 |
| Reidy, K | 1 |
| Tipple, TE | 1 |
| Jetton, JG | 1 |
| Kent, AL | 2 |
| Abitbol, CL | 1 |
| Ambalavanan, N | 1 |
| Mhanna, MJ | 1 |
| Askenazi, DJ | 1 |
| Selewski, DT | 1 |
| Harer, MW | 1 |
| Yang, L | 2 |
| Yu, X | 2 |
| Zhang, Y | 2 |
| Liu, N | 2 |
| Xue, X | 2 |
| Fu, J | 2 |
| Li, D | 1 |
| Bruschettini, M | 1 |
| Moreira, A | 1 |
| Pizarro, AB | 1 |
| Mustafa, S | 1 |
| Romantsik, O | 1 |
| Sabir, H | 1 |
| Maes, E | 1 |
| Zweyer, M | 1 |
| Schleehuber, Y | 1 |
| Imam, FB | 1 |
| Silverman, J | 1 |
| White, Y | 1 |
| Pang, R | 1 |
| Pasca, AM | 1 |
| Robertson, NJ | 1 |
| Maltepe, E | 1 |
| Bernis, ME | 1 |
| Groves, AM | 1 |
| Johnston, CJ | 1 |
| Beutner, G | 1 |
| Dahlstrom, JE | 1 |
| Koina, M | 1 |
| O'Reilly, M | 1 |
| Marples, B | 1 |
| Porter, G | 1 |
| Brophy, PD | 1 |
| Di Martino, E | 1 |
| Bocchetta, E | 1 |
| Tsuji, S | 1 |
| Mukai, T | 1 |
| Harris, RA | 1 |
| Blomgren, K | 1 |
| Ådén, U | 2 |
| Sun, H | 1 |
| Gonzalez, F | 1 |
| McQuillen, PS | 1 |
| El-Dib, M | 1 |
| Szakmar, E | 1 |
| Chakkarapani, E | 1 |
| Aly, H | 1 |
| Potter, M | 1 |
| Rosenkrantz, T | 1 |
| Fitch, RH | 1 |
| Kilicdag, H | 1 |
| Daglioglu, YK | 1 |
| Erdogan, S | 1 |
| Zorludemir, S | 1 |
| Xu, FL | 1 |
| Cheng, HQ | 1 |
| Wang, CH | 1 |
| Zhang, YH | 1 |
| Guo, JJ | 1 |
| Winerdal, M | 1 |
| Urmaliya, V | 1 |
| Winerdal, ME | 1 |
| Fredholm, BB | 1 |
| Winqvist, O | 1 |
| Rivkees, SA | 1 |
| Wendler, CC | 1 |
| Poets, CF | 1 |
| Mitkov, J | 1 |
| Danchev, N | 1 |
| Nikolova, I | 1 |
| Zlatkov, A | 1 |
| Strong, R | 1 |
| Grotta, JC | 1 |
| Aronowski, J | 1 |
| Gervitz, LM | 1 |
| Lutherer, LO | 1 |
| Davies, DG | 1 |
| Pirch, JH | 1 |
| Fowler, JC | 1 |
4 reviews available for caffeine and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Advances in Neonatal Acute Kidney Injury.
Topics: Acute Kidney Injury; Biomarkers; Caffeine; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Infant, | 2021 |
The effects of caffeine following hypoxic-ischemic encephalopathy: A systematic review of animal studies.
Topics: Animals; Brain; Caffeine; Drinking Water; Female; Humans; Hypoxia-Ischemia, Brain; Lactation; Male; | 2022 |
Challenges in respiratory management during therapeutic hypothermia for neonatal encephalopathy.
Topics: Brain; Caffeine; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn; Inf | 2021 |
Adverse and protective influences of adenosine on the newborn and embryo: implications for preterm white matter injury and embryo protection.
Topics: Adenosine; Animals; Caffeine; Embryo, Mammalian; Female; Humans; Hypoxia-Ischemia, Brain; Infant, Ne | 2011 |
14 other studies available for caffeine and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Caffeine treatment started before injury reduces hypoxic-ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization.
Topics: Animals; Animals, Newborn; Caffeine; Hypoxia-Ischemia, Brain; Inflammasomes; Ischemia; Microglia; NL | 2022 |
Proteomic analysis of the effects of caffeine in a neonatal rat model of hypoxic-ischemic white matter damage.
Topics: Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Humans; Hypoxia; Hypoxia-Ischemia, Brai | 2022 |
Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia-ischemia in newborn rats: a multi-drug randomized controlled screening trial.
Topics: Allopurinol; Animals; Animals, Newborn; Asphyxia Neonatorum; Brain; Brain Injuries; Caffeine; Clemas | 2023 |
Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model.
Topics: Acute Kidney Injury; Albumins; Animals; Animals, Newborn; Biomarkers; Caffeine; Humans; Hypoxia-Isch | 2023 |
Defining a Time Window for Neuroprotection and Glia Modulation by Caffeine After Neonatal Hypoxia-Ischaemia.
Topics: Animals; Brain Injuries; Caffeine; Demyelinating Diseases; DNA Fragmentation; Drug Administration Sc | 2020 |
Caffeine Restores Background EEG Activity Independent of Infarct Reduction after Neonatal Hypoxic Ischemic Brain Injury.
Topics: Animals; Brain; Brain Injuries; Caffeine; Disease Models, Animal; Hypoxia-Ischemia, Brain; Infarctio | 2020 |
Behavioral and neuroanatomical outcomes in a rat model of preterm hypoxic-ischemic brain Injury: Effects of caffeine and hypothermia.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Behavior, Animal; Brain; Caffeine; Central Nervous | 2018 |
Effects of caffeine on neuronal apoptosis in neonatal hypoxic-ischemic brain injury.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Caffeine; Disease Models, Animal; Female; Hypoxia-Ische | 2014 |
[Effects of caffeine citrate on myelin basic protein in neonatal rats with hypoxic-ischemic brain damage].
Topics: Animals; Animals, Newborn; Caffeine; Citrates; Female; Hypoxia-Ischemia, Brain; Male; Myelin Basic P | 2015 |
Single Dose Caffeine Protects the Neonatal Mouse Brain against Hypoxia Ischemia.
Topics: Animals; Animals, Newborn; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Human | 2017 |
What are the main research findings during the last 5 years that have changed my approach to clinical practice?
Topics: Apnea; Caffeine; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Extremely Premature; | 2013 |
Synthesis and brain antihypoxic activity of some aliphatic and arylaliphatic amides of caffeine-8-thioglycolic acid.
Topics: Administration, Oral; Animals; Caffeine; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Magne | 2007 |
Combination of low dose ethanol and caffeine protects brain from damage produced by focal ischemia in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Caffeine; Central Nervous System Depressants; Central Nervou | 2000 |
Adenosine induces initial hypoxic-ischemic depression of synaptic transmission in the rat hippocampus in vivo.
Topics: Acid-Base Equilibrium; Adenosine; Animals; Blood Pressure; Caffeine; Carotid Artery, Common; Constri | 2001 |