Page last updated: 2024-10-24

caffeine and Hyperglycemia, Postprandial

caffeine has been researched along with Hyperglycemia, Postprandial in 36 studies

Hyperglycemia, Postprandial: Abnormally high BLOOD GLUCOSE level after a meal.

Research Excerpts

ExcerptRelevanceReference
"Compounds other than macronutrients have been shown to influence blood glucose concentrations and insulin sensitivity in people with diabetes, with caffeine being one such substance."8.89Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013)
"We tested the hypothesis that long-term caffeine intake prevents the development of insulin resistance and hypertension in two pathological animal models: the high-fat (HF) and the high-sucrose (HSu) diet rat."7.78Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats. ( Conde, SV; Gonzalez, C; Guarino, MP; Monteiro, EC; Mota Carmo, M; Nunes da Silva, T, 2012)
"During the 49-day treatment, body weight and blood glucose were measured weekly."5.91A caffeine pre-treatment and sole effect of bone-marrow mesenchymal stem cells-derived conditioned media on hyperglycemia-suppressed fertilization. ( Abtahi-Foroushani, M; Babaei-Balderlou, F; Goshadezehn, P; Najafi, GR; Razi, M, 2023)
"Caffeine treatment has reduced cell monolayer permeability after exposure to high glucose and desferoxamine as shown by TEER and FITC-dextran permeability assays."5.46Caffeine Prevents Blood Retinal Barrier Damage in a Model, In Vitro, of Diabetic Macular Edema. ( Cavallaro, S; D'Agata, V; D'Amico, AG; Federico, C; La Cognata, V; Maugeri, G; Rasà, DM; Saccone, S, 2017)
"A comprehensive literature search was conducted to identify relevant trials of GTCs with or without caffeine on markers of glycemic control [fasting blood glucose (FBG), fasting blood insulin (FBI), glycated hemoglobin (Hb A1c), and homeostatic model assessment of insulin resistance (HOMA-IR)]."4.89Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials. ( Huang, XH; Hui, R; Li, SH; Wu, YJ; Xu, YL; Zheng, XX, 2013)
"Compounds other than macronutrients have been shown to influence blood glucose concentrations and insulin sensitivity in people with diabetes, with caffeine being one such substance."4.89Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013)
" We examined the effect of coffee, caffeine, or decaffeinated coffee ingestion on STZ-induced hyperglycemia."3.85Coffee Ingestion Suppresses Hyperglycemia in Streptozotocin-Induced Diabetic Mice. ( Hamana, Y; Hiramitsu, M; Horio, F; Inoue, T; Kobayashi, M; Kurata, T; Murai, A, 2017)
"Caffeine can stimulate insulin secretion by attenuating hyperglycemia in diabetes models with significant reduction of pancreatic functional β cells."3.80Sulfonylurea induction of caffeine-enhanced insulin secretion and reduction of glycemic levels in diabetic rats. ( Altimari, LR; da Silva, LA; Kerppers, II; Malfatti, CR; Osiecki, R; Pereira, RA; Túrmina, JA, 2014)
"We tested the hypothesis that long-term caffeine intake prevents the development of insulin resistance and hypertension in two pathological animal models: the high-fat (HF) and the high-sucrose (HSu) diet rat."3.78Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats. ( Conde, SV; Gonzalez, C; Guarino, MP; Monteiro, EC; Mota Carmo, M; Nunes da Silva, T, 2012)
"During the 49-day treatment, body weight and blood glucose were measured weekly."1.91A caffeine pre-treatment and sole effect of bone-marrow mesenchymal stem cells-derived conditioned media on hyperglycemia-suppressed fertilization. ( Abtahi-Foroushani, M; Babaei-Balderlou, F; Goshadezehn, P; Najafi, GR; Razi, M, 2023)
"Prolonged hyperglycemia was associated with increased chamber dilation, thinning of the left ventricle (LV), and myocyte loss."1.46Hyperglycemia induces defective Ca2+ homeostasis in cardiomyocytes. ( Anversa, P; Borghetti, G; Cannata, A; Goichberg, P; Hintze, TH; Jacobson, JT; Leri, A; Meo, M; Qanud, K; Rota, M; Signore, S; Sorrentino, A; Zhou, Y, 2017)
"Caffeine treatment has reduced cell monolayer permeability after exposure to high glucose and desferoxamine as shown by TEER and FITC-dextran permeability assays."1.46Caffeine Prevents Blood Retinal Barrier Damage in a Model, In Vitro, of Diabetic Macular Edema. ( Cavallaro, S; D'Agata, V; D'Amico, AG; Federico, C; La Cognata, V; Maugeri, G; Rasà, DM; Saccone, S, 2017)
" The hypoglycemic action of JAT was also confirmed: JAT, in combination with acarbose, produced a synergistic inhibitory effect on plasma glucose levels in vivo."1.42Inhibitory effect of black tea and its combination with acarbose on small intestinal α-glucosidase activity. ( Igarashi, M; Satoh, T; Takahashi, N; Watanabe, K; Yamada, S, 2015)
"05) different from that of acarbose at the same dosage (50 mg/kg BW), which indicate that these fractions could be developed as potential anti-diabetic agents."1.39Studies on the bioactivity of aqueous extract of pu-erh tea and its fractions: in vitro antioxidant activity and α-glycosidase inhibitory property, and their effect on postprandial hyperglycemia in diabetic mice. ( Chen, H; Chen, S; Hochstetter, D; Huang, Q; Wang, Y; Xu, P, 2013)
"Glycogen was depleted only by amphetamine-like compounds or by bemegride-induced convulsions."1.25Physiological and drug-induced changes in the glycogen content of mouse brain. ( Hutchins, DA; Rogers, KJ, 1970)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199011 (30.56)18.7374
1990's1 (2.78)18.2507
2000's6 (16.67)29.6817
2010's15 (41.67)24.3611
2020's3 (8.33)2.80

Authors

AuthorsStudies
Chen, J1
Liu, J1
Zhang, L1
Wu, G1
Hua, W1
Wu, X1
Sun, H1
Abdelkader, NF1
Ibrahim, SM1
Moustafa, PE1
Elbaset, MA1
Goshadezehn, P1
Babaei-Balderlou, F1
Razi, M1
Najafi, GR1
Abtahi-Foroushani, M1
Sang, J1
Dhakal, S1
Lee, Y1
Kobayashi, M2
Kurata, T1
Hamana, Y1
Hiramitsu, M1
Inoue, T2
Murai, A2
Horio, F2
Banks, NF1
Tomko, PM1
Colquhoun, RJ1
Muddle, TWD1
Emerson, SR1
Jenkins, NDM1
Zheng, XX1
Xu, YL1
Li, SH1
Hui, R1
Wu, YJ1
Huang, XH1
Alkaabi, J1
Al-Dabbagh, B1
Saadi, H1
Gariballa, S1
Yasin, J1
Kashani-Amin, E1
Yaghmaei, P1
Larijani, B1
Ebrahim-Habibi, A1
da Silva, LA1
Pereira, RA1
Túrmina, JA1
Kerppers, II1
Osiecki, R1
Altimari, LR1
Malfatti, CR1
Satoh, T1
Igarashi, M1
Yamada, S1
Takahashi, N1
Watanabe, K1
Katayama, M1
Sjögren, RJ1
Egan, B1
Krook, A1
Love, IY1
Perl, S1
Rapoport, MJ1
Sorrentino, A1
Borghetti, G1
Zhou, Y1
Cannata, A1
Meo, M1
Signore, S1
Anversa, P1
Leri, A1
Goichberg, P1
Qanud, K1
Jacobson, JT1
Hintze, TH1
Rota, M1
Maugeri, G1
D'Amico, AG1
Rasà, DM1
La Cognata, V1
Saccone, S1
Federico, C1
Cavallaro, S1
D'Agata, V1
Salahdeen, HM1
Alada, AR1
Yamauchi, R1
Matsuda, Y1
Ojika, M1
Shigeoka, S1
Yamamoto, Y1
Tou, Y1
Katagiri, T1
Conde, SV1
Nunes da Silva, T1
Gonzalez, C1
Mota Carmo, M1
Monteiro, EC1
Guarino, MP1
Huang, Q1
Chen, S1
Chen, H1
Wang, Y2
Hochstetter, D1
Xu, P1
Whitehead, N1
White, H1
Mokelke, EA1
Wang, M1
Sturek, M1
Isogawa, A1
Noda, M1
Takahashi, Y1
Kadowaki, T1
Tsugane, S1
KUFTINEC, DM1
MAYER, J1
Kerr, D1
Everett, J1
Kaplan, M1
Benowitz, NL1
Osterloh, J1
Goldschlager, N1
Kaysen, G1
Pond, S1
Forhan, S1
Ahmed, M1
Grapengiesser, E1
Edwardson, JM1
Dean, PM1
Hoeldtke, RD1
O'Dorisio, TM1
Boden, G1
Leson, CL1
McGuigan, MA1
Bryson, SM1
Marks, V1
Alberti, KG1
Hockaday, TD1
Williamson, DH1
Junod, A1
Letarte, J1
Lambert, AE1
Stauffacher, W1
Hutchins, DA1
Rogers, KJ1
Bukowski, Z1
Iwanowski, J1
Heyden, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Caffeine on the Narcoleptic Patients Randomized Controlled Clinical Trial[NCT02832336]Phase 1/Phase 216 participants (Actual)Interventional2016-10-01Completed
Effect of Date Fruit Phytoestrogen on the Glycemic Control of Patients With Type 2 Diabetes: A Randomized Clinical Trial.[NCT04616066]79 participants (Actual)Interventional2021-10-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for caffeine and Hyperglycemia, Postprandial

ArticleYear
Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:4

    Topics: Adult; Blood Glucose; Caffeine; Camellia sinensis; Catechin; Glycated Hemoglobin; Humans; Hyperglyce

2013
Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2013, Volume: 26, Issue:2

    Topics: Beverages; Blood Glucose; Caffeine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes,

2013

Trials

2 trials available for caffeine and Hyperglycemia, Postprandial

ArticleYear
Genetic Polymorphisms in ADORA2A and CYP1A2 Influence Caffeine's Effect on Postprandial Glycaemia.
    Scientific reports, 2019, 07-19, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Area Under Curve; Blood Glucose; Body Composition; Caffeine; Cytochrome P-450 CYP

2019
Treatment of autonomic neuropathy with a somatostatin analogue SMS-201-995.
    Lancet (London, England), 1986, Sep-13, Volume: 2, Issue:8507

    Topics: Adult; Aged; Autonomic Nervous System Diseases; Blood Pressure; Caffeine; Chronic Disease; Female; H

1986

Other Studies

32 other studies available for caffeine and Hyperglycemia, Postprandial

ArticleYear
Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Bioorganic & medicinal chemistry letters, 2006, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Blood Glucose; Cyclization; Enzyme Inhibitors; Glycogen Phosphorylase; Hyperglycemia; Mice;

2006
Inosine mitigated diabetic peripheral neuropathy via modulating GLO1/AGEs/RAGE/NF-κB/Nrf2 and TGF-β/PKC/TRPV1 signaling pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 145

    Topics: Animals; Caffeine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperglycemia; Hypoglycem

2022
A caffeine pre-treatment and sole effect of bone-marrow mesenchymal stem cells-derived conditioned media on hyperglycemia-suppressed fertilization.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Animals; Antioxidants; Body Weight; Bone Marrow; Caffeine; Chromatin; Culture Media, Conditioned; Fe

2023
Cucurbitacin B Suppresses Hyperglycemia Associated with a High Sugar Diet and Promotes Sleep in
    Molecules and cells, 2021, Feb-28, Volume: 44, Issue:2

    Topics: Animals; Caffeine; Diet; Dietary Sugars; Drosophila melanogaster; Drosophila Proteins; Feeding Behav

2021
Coffee Ingestion Suppresses Hyperglycemia in Streptozotocin-Induced Diabetic Mice.
    Journal of nutritional science and vitaminology, 2017, Volume: 63, Issue:3

    Topics: Animals; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Experimental; Hyperglycemia; Insulin; I

2017
Effect of traditional Arabic coffee consumption on the glycemic index of Khalas dates tested in healthy and diabetic subjects.
    Asia Pacific journal of clinical nutrition, 2013, Volume: 22, Issue:4

    Topics: Adult; Arecaceae; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dietary Carbohydrates;

2013
Effect of traditional Arabic coffee consumption on the glycemic index of Khalas dates tested in healthy and diabetic subjects.
    Asia Pacific journal of clinical nutrition, 2013, Volume: 22, Issue:4

    Topics: Adult; Arecaceae; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dietary Carbohydrates;

2013
Effect of traditional Arabic coffee consumption on the glycemic index of Khalas dates tested in healthy and diabetic subjects.
    Asia Pacific journal of clinical nutrition, 2013, Volume: 22, Issue:4

    Topics: Adult; Arecaceae; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dietary Carbohydrates;

2013
Effect of traditional Arabic coffee consumption on the glycemic index of Khalas dates tested in healthy and diabetic subjects.
    Asia Pacific journal of clinical nutrition, 2013, Volume: 22, Issue:4

    Topics: Adult; Arecaceae; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dietary Carbohydrates;

2013
Xanthine derivatives as activators of alpha-amylase: hypothesis on a link with the hyperglycemia induced by caffeine.
    Obesity research & clinical practice, 2013, Volume: 7, Issue:6

    Topics: Animals; Blood Glucose; Caffeine; Enzyme Activation; Enzyme Inhibitors; Hyperglycemia; Pancreas; Pan

2013
Sulfonylurea induction of caffeine-enhanced insulin secretion and reduction of glycemic levels in diabetic rats.
    Pharmaceutical biology, 2014, Volume: 52, Issue:8

    Topics: Animals; Blood Glucose; Caffeine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Hyperg

2014
Inhibitory effect of black tea and its combination with acarbose on small intestinal α-glucosidase activity.
    Journal of ethnopharmacology, 2015, Feb-23, Volume: 161

    Topics: Acarbose; alpha-Amylases; alpha-Glucosidases; Animals; Biflavonoids; Blood Glucose; Caco-2 Cells; Ca

2015
miRNA let-7 expression is regulated by glucose and TNF-α by a remote upstream promoter.
    The Biochemical journal, 2015, Dec-01, Volume: 472, Issue:2

    Topics: Blood Glucose; Caffeine; Cells, Cultured; Chromosomes, Human, Pair 9; Computational Biology; Databas

2015
A Rare Case of Caffeine Storm due to Excessive Coca-Cola Consumption.
    The Israel Medical Association journal : IMAJ, 2016, Volume: 18, Issue:6

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Diabetic Ketoacidosis; Diagnosis, Differential;

2016
Hyperglycemia induces defective Ca2+ homeostasis in cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2017, Jan-01, Volume: 312, Issue:1

    Topics: Action Potentials; Animals; Caffeine; Calcium; Central Nervous System Stimulants; Diabetes Mellitus,

2017
Caffeine Prevents Blood Retinal Barrier Damage in a Model, In Vitro, of Diabetic Macular Edema.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:8

    Topics: Blood-Retinal Barrier; Blotting, Western; Caffeine; Cell Death; Cell Line; Humans; Hyperglycemia; Ma

2017
Role of adrenergic receptors in the caffeine-induced increase in glucose uptake by the canine hindlimb.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2009, Volume: 24, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Biological Transport; Blood Gluc

2009
Coffee and caffeine ameliorate hyperglycemia, fatty liver, and inflammatory adipocytokine expression in spontaneously diabetic KK-Ay mice.
    Journal of agricultural and food chemistry, 2010, May-12, Volume: 58, Issue:9

    Topics: Adipokines; Animals; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Experimental; Fatty Liver;

2010
Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats.
    The British journal of nutrition, 2012, Volume: 107, Issue:1

    Topics: Adiposity; Adrenergic Antagonists; Animals; Body Weight; Caffeine; Carbazoles; Carvedilol; Catechola

2012
Studies on the bioactivity of aqueous extract of pu-erh tea and its fractions: in vitro antioxidant activity and α-glycosidase inhibitory property, and their effect on postprandial hyperglycemia in diabetic mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Amino Acids; Animals; Antioxidants; Blood Glucose; Caffeine; Diabetes Mellitus, Experimental; Glycos

2013
Exercise training enhances coronary smooth muscle cell sodium-calcium exchange activity in diabetic dyslipidemic Yucatan swine.
    Annals of the New York Academy of Sciences, 2002, Volume: 976

    Topics: Animals; Caffeine; Cholesterol, Dietary; Coronary Vessels; Diabetes Mellitus; Dietary Fats; Disease

2002
Coffee consumption and risk of type 2 diabetes mellitus.
    Lancet (London, England), 2003, Feb-22, Volume: 361, Issue:9358

    Topics: Adult; Caffeine; Cross-Sectional Studies; Female; Humans; Hyperglycemia; Japan; Male; Middle Aged; R

2003
EXTREME SENSITIVITY OF OBESE HYPERGLYCEMIC MICE TO CAFFEINE AND COFFEE.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Alloxan; Animals; Blood Glucose; Caffeine; Coffee; Glucose Tolerance Test; Hyperglycemia; Insulin; M

1964
Coffee, diabetes and insulin sensitivity.
    Diabetologia, 2005, Volume: 48, Issue:7

    Topics: Adult; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Hyperg

2005
Fetal breathing movements. An update for the pediatrician.
    American journal of diseases of children (1960), 1983, Volume: 137, Issue:2

    Topics: Anesthesia, General; Animals; Barbiturates; Caffeine; Central Nervous System; Circadian Rhythm; Fema

1983
Massive catecholamine release from caffeine poisoning.
    JAMA, 1982, Sep-03, Volume: 248, Issue:9

    Topics: Adult; Affective Symptoms; Caffeine; Catecholamines; Female; Humans; Hyperglycemia; Hyperventilation

1982
Pancreatic beta-cells from obese-hyperglycemic mice are characterized by excessive firing of cytoplasmic Ca2+ transients.
    Endocrine, 2001, Volume: 15, Issue:1

    Topics: Animals; Caffeine; Calcium; Cytoplasm; Glucagon; Hyperglycemia; Islets of Langerhans; Leptin; Mice;

2001
Inhibition of alloxan-induced hyperglycaemia by compounds of similar molecular structure.
    Biochemical pharmacology, 1992, Dec-01, Volume: 44, Issue:11

    Topics: Allantoin; Alloxan; Animals; Barbiturates; Blood Glucose; Caffeine; Ethosuximide; Hyperglycemia; Ino

1992
Caffeine overdose in an adolescent male.
    Journal of toxicology. Clinical toxicology, 1988, Volume: 26, Issue:5-6

    Topics: Adolescent; Alkalosis, Respiratory; Caffeine; Chest Pain; Humans; Hyperglycemia; Hypokalemia; Illici

1988
Effect of drugs on carbohydrate metabolism.
    The Proceedings of the Nutrition Society, 1974, Volume: 33, Issue:3

    Topics: Adult; Blood Glucose; Caffeine; Carbohydrate Metabolism; Carbohydrate Metabolism, Inborn Errors; Chi

1974
Metabolic effects of chronic caffeine administration in a patient with diabetes mellitus.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:5

    Topics: Caffeine; Diabetes Mellitus; Fatty Acids, Nonesterified; Humans; Hyperglycemia; Ketone Bodies; Male;

1972
Studies in spiny mice (Acomys cahirinus): metabolic state and pancreatic insulin release in vitro.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1969, Volume: 1, Issue:2

    Topics: Age Factors; Animals; Antigens; Arginine; Blood Glucose; Caffeine; Calcium; Diabetes Mellitus; Gluca

1969
Physiological and drug-induced changes in the glycogen content of mouse brain.
    British journal of pharmacology, 1970, Volume: 39, Issue:1

    Topics: Amphetamine; Animals; Bemegride; Body Temperature; Brain Chemistry; Caffeine; Catecholamines; Circad

1970
[Effect of caffeine on the hyperglycemic curve].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1970, Aug-03, Volume: 25, Issue:31

    Topics: Administration, Oral; Adolescent; Adult; Caffeine; Carbohydrate Metabolism; Glucose; Humans; Hypergl

1970
[The BBC study. Applied epidemiology of ischemic heart diseases].
    Archiv fur Kreislaufforschung, 1967, Volume: 53, Issue:1

    Topics: Adult; Body Weight; Caffeine; Cholesterol; Coronary Disease; Epidemiologic Methods; Hematocrit; Huma

1967