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caffeine and Hypercapnia

caffeine has been researched along with Hypercapnia in 21 studies

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
"The effect of oral caffeine on resting ventilation (VE), ventilatory responsiveness to progressive hyperoxic hypercapnia (HCVR), isocapnic hypoxia (HVR), and moderate exercise (EVR) below the anaerobic threshold (AT) was examined in seven healthy adults."9.06Effect of caffeine on ventilatory responses to hypercapnia, hypoxia, and exercise in humans. ( Avendano, MA; D'Costa, M; D'Urzo, AD; Goldstein, RS; Jenne, H; Jhirad, R; Rubenstein, I; Rubinstein, I, 1990)
"Apnea of prematurity (AOP) is a significant clinical problem manifested by an unstable respiratory rhythm reflecting the immaturity of respiratory control systems."8.87Apnea of prematurity: pathogenesis and management strategies. ( Mathew, OP, 2011)
"Caffeine is an adenosine receptor antagonist commonly used as a respiratory stimulant to treat neonatal apneas of premature newborn."7.73Long-term consequences of neonatal caffeine on ventilation, occurrence of apneas, and hypercapnic chemoreflex in male and female rats. ( Bairam, A; Kinkead, R; Montandon, G, 2006)
"The role of adenosine in rat coronary flow regulation during acidosis was evaluated in isolated, perfused, Langendorff rat heart preparations exposed to brief periods of hypercapnic or metabolic acidosis."7.70The role of adenosine in rat coronary flow regulation during respiratory and metabolic acidosis. ( O'Regan, MH; Phillis, JW; Song, D, 1998)
"This study characterized in rhesus monkeys the effects of selected adenosine agonists on ventilation during normal atmospheric conditions and during conditions of hypercapnia, hypoxia and hyperoxia."7.68Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxia in rhesus monkeys. ( Howell, LL, 1993)
"The possibility that endogenously released adenosine, a potent vasodilator, is involved in the increase in cerebral blood flow (CBF) response to hypercapnia has been investigated in an anesthetized, paralyzed rat model."7.67An involvement of adenosine in cerebral blood flow regulation during hypercapnia. ( DeLong, RE; Phillis, JW, 1987)
"Caffeine-treated chronically hypoxic rats exhibited a decrease in the CSN response to acute hypoxia tests but maintained ventilation compared with chronically hypoxic animals."5.38Chronic caffeine intake in adult rat inhibits carotid body sensitization produced by chronic sustained hypoxia but maintains intact chemoreflex output. ( Conde, SV; Gonzalez, C; Monteiro, EC; Obeso, A; Ribeiro, MJ; Rigual, R, 2012)
"The effect of oral caffeine on resting ventilation (VE), ventilatory responsiveness to progressive hyperoxic hypercapnia (HCVR), isocapnic hypoxia (HVR), and moderate exercise (EVR) below the anaerobic threshold (AT) was examined in seven healthy adults."5.06Effect of caffeine on ventilatory responses to hypercapnia, hypoxia, and exercise in humans. ( Avendano, MA; D'Costa, M; D'Urzo, AD; Goldstein, RS; Jenne, H; Jhirad, R; Rubenstein, I; Rubinstein, I, 1990)
"Apnea of prematurity (AOP) is a significant clinical problem manifested by an unstable respiratory rhythm reflecting the immaturity of respiratory control systems."4.87Apnea of prematurity: pathogenesis and management strategies. ( Mathew, OP, 2011)
" The model reproduces salient features of BOLD signal dynamics under conditions such as hypercapnia, hyperoxia, and caffeine intake, where both brain physiology and BOLD characteristics are altered."3.88The effects of capillary transit time heterogeneity on the BOLD signal. ( Angleys, H; Jespersen, SN; Østergaard, L, 2018)
"Caffeine is an adenosine receptor antagonist commonly used as a respiratory stimulant to treat neonatal apneas of premature newborn."3.73Long-term consequences of neonatal caffeine on ventilation, occurrence of apneas, and hypercapnic chemoreflex in male and female rats. ( Bairam, A; Kinkead, R; Montandon, G, 2006)
"The role of adenosine in rat coronary flow regulation during acidosis was evaluated in isolated, perfused, Langendorff rat heart preparations exposed to brief periods of hypercapnic or metabolic acidosis."3.70The role of adenosine in rat coronary flow regulation during respiratory and metabolic acidosis. ( O'Regan, MH; Phillis, JW; Song, D, 1998)
"This study characterized in rhesus monkeys the effects of selected adenosine agonists on ventilation during normal atmospheric conditions and during conditions of hypercapnia, hypoxia and hyperoxia."3.68Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxia in rhesus monkeys. ( Howell, LL, 1993)
"The possibility that endogenously released adenosine, a potent vasodilator, is involved in the increase in cerebral blood flow (CBF) response to hypercapnia has been investigated in an anesthetized, paralyzed rat model."3.67An involvement of adenosine in cerebral blood flow regulation during hypercapnia. ( DeLong, RE; Phillis, JW, 1987)
"Caffeine has been shown to enhance the speed of recovery from general anesthesia in murine models, though data in human patients is lacking."1.48Effects of caffeine administration on sedation and respiratory parameters in patients recovering from anesthesia. ( Schroeder, DR; Sprung, J; Warner, MA; Warner, NS; Weingarten, TN, 2018)
"Caffeine-treated chronically hypoxic rats exhibited a decrease in the CSN response to acute hypoxia tests but maintained ventilation compared with chronically hypoxic animals."1.38Chronic caffeine intake in adult rat inhibits carotid body sensitization produced by chronic sustained hypoxia but maintains intact chemoreflex output. ( Conde, SV; Gonzalez, C; Monteiro, EC; Obeso, A; Ribeiro, MJ; Rigual, R, 2012)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's5 (23.81)18.2507
2000's4 (19.05)29.6817
2010's7 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Warner, NS1
Warner, MA1
Schroeder, DR1
Sprung, J1
Weingarten, TN1
Angleys, H1
Jespersen, SN1
Østergaard, L1
van der Heijden, ME1
Zoghbi, HY1
Vidyasagar, R1
Greyling, A1
Draijer, R1
Corfield, DR1
Parkes, LM1
Riazi, S1
Larach, MG1
Hu, C1
Wijeysundera, D1
Massey, C1
Kraeva, N1
Mathew, OP1
Conde, SV1
Ribeiro, MJ1
Obeso, A1
Rigual, R1
Monteiro, EC1
Gonzalez, C1
Montandon, G2
Bairam, A2
Kinkead, R2
Blaha, M1
Benes, V1
Douville, CM1
Newell, DW1
Perthen, JE1
Lansing, AE1
Liau, J1
Liu, TT1
Buxton, RB1
Kaplan, M1
Gautier, H2
Bonora, M2
Pianosi, P1
Grondin, D1
Desmond, K1
Coates, AL1
Aranda, JV1
Howell, LL1
Phillis, JW2
Song, D1
O'Regan, MH1
Lewis, P1
Boylan, P1
Milic-Emili, J1
Siafakas, NM1
Nutt, D1
Lawson, C1
D'Urzo, AD1
Jhirad, R1
Jenne, H1
Avendano, MA1
Rubinstein, I1
D'Costa, M1
Goldstein, RS1
Rubenstein, I1
DeLong, RE1

Reviews

2 reviews available for caffeine and Hypercapnia

ArticleYear
Apnea of prematurity: pathogenesis and management strategies.
    Journal of perinatology : official journal of the California Perinatal Association, 2011, Volume: 31, Issue:5

    Topics: Apnea; Arrhythmias, Cardiac; Brain Stem; Caffeine; Central Nervous System Stimulants; Continuous Pos

2011
Panic attacks. A neurochemical overview of models and mechanisms.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Bicarbonates; Caffeine; Female; Humans; Hypercapnia; Hyperventilation; Lactates; Lactic Acid; Male;

1992

Trials

3 trials available for caffeine and Hypercapnia

ArticleYear
The effect of caffeine on dilated cerebral circulation and on diagnostic CO2 reactivity testing.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2007, Volume: 14, Issue:5

    Topics: Adult; Caffeine; Carbon Dioxide; Central Nervous System Stimulants; Cerebrovascular Circulation; Fem

2007
Effect of caffeine on the ventilatory response to inhaled carbon dioxide.
    Respiration physiology, 1994, Volume: 95, Issue:3

    Topics: Administration, Inhalation; Adult; Bronchodilator Agents; Caffeine; Carbon Dioxide; Double-Blind Met

1994
Effect of caffeine on ventilatory responses to hypercapnia, hypoxia, and exercise in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:1

    Topics: Administration, Oral; Adult; Caffeine; Chemoreceptor Cells; Double-Blind Method; Exercise; Humans; H

1990

Other Studies

16 other studies available for caffeine and Hypercapnia

ArticleYear
Effects of caffeine administration on sedation and respiratory parameters in patients recovering from anesthesia.
    Bosnian journal of basic medical sciences, 2018, Feb-20, Volume: 18, Issue:1

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Caffeine; Central Nervous System Stimu

2018
The effects of capillary transit time heterogeneity on the BOLD signal.
    Human brain mapping, 2018, Volume: 39, Issue:6

    Topics: Brain; Brain Mapping; Caffeine; Hemodynamics; Humans; Hypercapnia; Image Processing, Computer-Assist

2018
Loss of
    eLife, 2018, 07-04, Volume: 7

    Topics: Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Caffeine; Cell

2018
The effect of black tea and caffeine on regional cerebral blood flow measured with arterial spin labeling.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2013, Volume: 33, Issue:6

    Topics: Adult; Brain; Caffeine; Camellia sinensis; Cerebrovascular Circulation; Double-Blind Method; Humans;

2013
Malignant hyperthermia in Canada: characteristics of index anesthetics in 129 malignant hyperthermia susceptible probands.
    Anesthesia and analgesia, 2014, Volume: 118, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthetics; Caffeine; Canada; Child; Child, Preschool; Dantrolene; Female;

2014
Chronic caffeine intake in adult rat inhibits carotid body sensitization produced by chronic sustained hypoxia but maintains intact chemoreflex output.
    Molecular pharmacology, 2012, Volume: 82, Issue:6

    Topics: Acclimatization; Adenosine; Animals; Caffeine; Carotid Body; Carotid Sinus; Chemoreceptor Cells; Dop

2012
Long-term consequences of neonatal caffeine on ventilation, occurrence of apneas, and hypercapnic chemoreflex in male and female rats.
    Pediatric research, 2006, Volume: 59, Issue:4 Pt 1

    Topics: Animals; Animals, Newborn; Apnea; Caffeine; Central Nervous System Stimulants; Female; Humans; Hyper

2006
Disruption of adenosinergic modulation of ventilation at rest and during hypercapnia by neonatal caffeine in young rats: role of adenosine A(1) and A(2A) receptors.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 292, Issue:4

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Central Ner

2007
Caffeine-induced uncoupling of cerebral blood flow and oxygen metabolism: a calibrated BOLD fMRI study.
    NeuroImage, 2008, Mar-01, Volume: 40, Issue:1

    Topics: Adult; Caffeine; Calibration; Central Nervous System Stimulants; Cerebrovascular Circulation; Dose-R

2008
Fetal breathing movements. An update for the pediatrician.
    American journal of diseases of children (1960), 1983, Volume: 137, Issue:2

    Topics: Anesthesia, General; Animals; Barbiturates; Caffeine; Central Nervous System; Circadian Rhythm; Fema

1983
Possible alterations in brain monoamine metabolism during hypoxia-induced tachypnea in cats.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1980, Volume: 49, Issue:5

    Topics: Aminophylline; Animals; Biogenic Amines; Brain; Caffeine; Carbidopa; Cats; Dihydroxyphenylalanine; D

1980
Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxia in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Carbon Dioxide; Female; Hypercapnia

1993
The role of adenosine in rat coronary flow regulation during respiratory and metabolic acidosis.
    European journal of pharmacology, 1998, Sep-04, Volume: 356, Issue:2-3

    Topics: Acidosis; Acidosis, Respiratory; Adenosine; Animals; Caffeine; Coronary Circulation; Hypercapnia; Ma

1998
Fetal breathing: a review.
    American journal of obstetrics and gynecology, 1979, Jul-01, Volume: 134, Issue:5

    Topics: Amniocentesis; Animals; Barbiturates; Benzodiazepines; Betamethasone; Blood Glucose; Blood Pressure;

1979
[Ventilatory effects of various respiratory stimulants in awake cats (author's transl)].
    Bulletin europeen de physiopathologie respiratoire, 1979, Volume: 15 Suppl

    Topics: Almitrine; Animals; Caffeine; Carbon Dioxide; Cats; Central Nervous System; Central Nervous System S

1979
An involvement of adenosine in cerebral blood flow regulation during hypercapnia.
    General pharmacology, 1987, Volume: 18, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Cerebrovascular Circulation; Coformycin; Dipyridamole;

1987