caffeine has been researched along with Huntington Disease in 10 studies
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Movement disorders including Parkinson's disease (PD), Huntington's disease (HD), chorea, tics, and Tourette's syndrome (TS) display sex differences in disease susceptibility, disease pathogenesis, and clinical presentation." | 2.50 | Sex differences in Parkinson's disease and other movement disorders. ( Dahodwala, N; Smith, KM, 2014) |
| " Chronic intake of caffeine was recently shown to be positively associated with the disease onset of HD." | 2.50 | Adenosine receptors and Huntington's disease. ( Chern, Y; Lee, CF, 2014) |
| "Neurodegenerative disorders are some of the most feared illnesses in modern society, with no effective treatments to slow or halt this neurodegeneration." | 2.47 | Impacts of methylxanthines and adenosine receptors on neurodegeneration: human and experimental studies. ( Chen, JF; Chern, Y, 2011) |
| "In a C." | 1.48 | Coffee extract and caffeine enhance the heat shock response and promote proteostasis in an HSF-1-dependent manner in Caenorhabditis elegans. ( Brunquell, J; Morris, S; Snyder, A; Westerheide, SD, 2018) |
| "Pre-treatment with dantrolene protected YAC128 MSNs from glutamate excitotoxicty, with an effective concentration of 100 nM and above." | 1.37 | Dantrolene is neuroprotective in Huntington's disease transgenic mouse model. ( Bezprozvanny, I; Chen, X; Herndon, E; Lvovskaya, S; Supnet, C; Wu, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brunquell, J | 1 |
| Morris, S | 1 |
| Snyder, A | 1 |
| Westerheide, SD | 1 |
| Simonin, C | 1 |
| Duru, C | 1 |
| Salleron, J | 1 |
| Hincker, P | 1 |
| Charles, P | 1 |
| Delval, A | 1 |
| Youssov, K | 1 |
| Burnouf, S | 1 |
| Azulay, JP | 1 |
| Verny, C | 1 |
| Scherer, C | 1 |
| Tranchant, C | 1 |
| Goizet, C | 1 |
| Debruxelles, S | 1 |
| Defebvre, L | 1 |
| Sablonnière, B | 1 |
| Romon-Rousseaux, M | 1 |
| Buée, L | 1 |
| Destée, A | 1 |
| Godefroy, O | 1 |
| Dürr, A | 1 |
| Landwehrmeyer, B | 1 |
| Bachoud-Levi, AC | 1 |
| Richard, F | 1 |
| Blum, D | 1 |
| Krystkowiak, P | 1 |
| Smith, KM | 1 |
| Dahodwala, N | 1 |
| Lee, CF | 1 |
| Chern, Y | 2 |
| Mishra, J | 1 |
| Kumar, A | 1 |
| Chen, JF | 1 |
| Chen, X | 1 |
| Wu, J | 1 |
| Lvovskaya, S | 1 |
| Herndon, E | 1 |
| Supnet, C | 1 |
| Bezprozvanny, I | 1 |
| Giuliano, P | 1 |
| De Cristofaro, T | 1 |
| Affaitati, A | 1 |
| Pizzulo, GM | 1 |
| Feliciello, A | 1 |
| Criscuolo, C | 1 |
| De Michele, G | 1 |
| Filla, A | 1 |
| Avvedimento, EV | 1 |
| Varrone, S | 1 |
| Boorstein, R | 1 |
| Campisi, J | 1 |
| Pardee, AB | 1 |
| Shoulson, I | 1 |
| Chase, T | 1 |
3 reviews available for caffeine and Huntington Disease
| Article | Year |
|---|---|
Sex differences in Parkinson's disease and other movement disorders.
Topics: Androgens; Animals; Caffeine; Chorea Gravidarum; Dopamine; Estrogens; Female; Humans; Huntington Dis | 2014 |
Adenosine receptors and Huntington's disease.
Topics: Animals; Autophagy; Caffeine; Humans; Huntington Disease; Metabolic Diseases; Mitochondrial Diseases | 2014 |
Impacts of methylxanthines and adenosine receptors on neurodegeneration: human and experimental studies.
Topics: Alzheimer Disease; Animals; Brain Injuries; Caffeine; Humans; Huntington Disease; Neurodegenerative | 2011 |
1 trial available for caffeine and Huntington Disease
| Article | Year |
|---|---|
Caffeine and the antiparkinsonian response to levodopa or piribedil.
Topics: Adult; Aged; Caffeine; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; | 1975 |
6 other studies available for caffeine and Huntington Disease
| Article | Year |
|---|---|
Coffee extract and caffeine enhance the heat shock response and promote proteostasis in an HSF-1-dependent manner in Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Caffeine; Coffee; Disease Models, Animal; Diterpenes; Heat Shock Tr | 2018 |
Association between caffeine intake and age at onset in Huntington's disease.
Topics: Adult; Age of Onset; Caffeine; Coffea; Female; France; Humans; Huntington Disease; Linear Models; Lo | 2013 |
Improvement of mitochondrial NAD(+)/FAD(+)-linked state-3 respiration by caffeine attenuates quinolinic acid induced motor impairment in rats: implications in Huntington's disease.
Topics: Animals; Antioxidants; Caffeine; Cell Respiration; Corpus Striatum; Disease Models, Animal; Dose-Res | 2014 |
Dantrolene is neuroprotective in Huntington's disease transgenic mouse model.
Topics: Animals; Apoptosis; Caffeine; Calcium; Calcium Signaling; Cells, Cultured; Central Nervous System St | 2011 |
DNA damage induced by polyglutamine-expanded proteins.
Topics: Amino Acid Sequence; Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycl | 2003 |
The study of DNA-repair defects using [125I]iododeoxycytidine incorporation as an assay for the growth of herpes simplex virus.
Topics: Ataxia Telangiectasia; Bloom Syndrome; Bromodeoxycytidine; Caffeine; Cell Cycle; Cells, Cultured; De | 1983 |