caffeine has been researched along with Hepatic Porphyria in 2 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " RNAi therapeutics, such as givosiran, have a low liability for drug-drug interactions (DDIs) because they are not metabolized by cytochrome 450 (CYP) enzymes, and do not directly inhibit or induce CYP enzymes in the liver." | 3.01 | A Drug-Drug Interaction Study Evaluating the Effect of Givosiran, a Small Interfering Ribonucleic Acid, on Cytochrome P450 Activity in the Liver. ( Agarwal, S; Clausen, VA; Harper, P; Najafian, N; Robbie, GJ; Sardh, E; Simon, AR; Vassiliou, D, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vassiliou, D | 1 |
| Sardh, E | 1 |
| Harper, P | 1 |
| Simon, AR | 1 |
| Clausen, VA | 1 |
| Najafian, N | 1 |
| Robbie, GJ | 1 |
| Agarwal, S | 1 |
| Mustajoki, P | 1 |
| Mustajoki, S | 1 |
| Rautio, A | 1 |
| Arvela, P | 1 |
| Pelkonen, O | 1 |
1 trial available for caffeine and Hepatic Porphyria
| Article | Year |
|---|---|
A Drug-Drug Interaction Study Evaluating the Effect of Givosiran, a Small Interfering Ribonucleic Acid, on Cytochrome P450 Activity in the Liver.
Topics: 5-Aminolevulinate Synthetase; Acetylgalactosamine; Adult; Caffeine; Cross-Over Studies; Cytochrome P | 2021 |
1 other study available for caffeine and Hepatic Porphyria
| Article | Year |
|---|---|
Effects of heme arginate on cytochrome P450-mediated metabolism of drugs in patients with variegate porphyria and in healthy men.
Topics: Adult; Arginine; Caffeine; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Heme; Hum | 1994 |