caffeine has been researched along with Glioma in 22 studies
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 8.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
| "Viability, cell cycle distribution, and expressions of eukaryotic translation initiation factor-2α (eIF-2α), cyclin D1, poly(ADP-ribose) polymerase 1 (PARP-1), and apoptosis-inducing factor (AIF) of RT-2 glioma cells were assayed under treatment of tetrandrine and caffeine for 48 h." | 7.80 | Tetrandrine and caffeine modulated cell cycle and increased glioma cell death via caspase-dependent and caspase-independent apoptosis pathways. ( Chan, YC; Chen, JC; Chiu, WH; Hwang, JH, 2014) |
| "Caffeine decreased the migration of rat C6 and human U87MG glioma cells and down-regulated the expression of phosphorylated focal adhesion kinase (p-FAK) and p-paxillin." | 7.80 | Caffeine inhibits migration in glioma cells through the ROCK-FAK pathway. ( Chen, Y; Chou, WC; Ding, YM; Wu, YC, 2014) |
| "We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk." | 7.78 | Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study. ( Darefsky, AS; Dubrow, R; Freedman, ND; Hollenbeck, AR; Sinha, R, 2012) |
| "To elucidate the mechanisms of the intracellular signal transduction elicited with bradykinin in NG108-15 neuroblastoma x glioma hybrid cells, we examined the activation of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) by bradykinin stimulation." | 7.68 | Activation of Ca2+/calmodulin-dependent protein kinase II by stimulation with bradykinin in neuroblastoma x glioma hybrid NG108-15 cells. ( Fukunaga, K; Higashida, H; Miyamoto, E; Yamakawa, T, 1992) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 5.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "In vitro, caffeine treatment reduced glioma cell proliferation through G(0)/G(1)-phase cell cycle arrest by suppressing Rb phosphorylation." | 5.37 | Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. ( Cho, GJ; Cho, YW; Choi, J; Choi, WS; Jeong, JY; Kang, SS; Kim, HJ; Kim, JS; Ku, BM; Lee, YK; Roh, GS; Ryu, J, 2011) |
| "Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect." | 5.36 | Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. ( Giovannucci, E; Holick, CN; Michaud, DS; Smith, SG, 2010) |
| "Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 4.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
| "Viability, cell cycle distribution, and expressions of eukaryotic translation initiation factor-2α (eIF-2α), cyclin D1, poly(ADP-ribose) polymerase 1 (PARP-1), and apoptosis-inducing factor (AIF) of RT-2 glioma cells were assayed under treatment of tetrandrine and caffeine for 48 h." | 3.80 | Tetrandrine and caffeine modulated cell cycle and increased glioma cell death via caspase-dependent and caspase-independent apoptosis pathways. ( Chan, YC; Chen, JC; Chiu, WH; Hwang, JH, 2014) |
| "Caffeine decreased the migration of rat C6 and human U87MG glioma cells and down-regulated the expression of phosphorylated focal adhesion kinase (p-FAK) and p-paxillin." | 3.80 | Caffeine inhibits migration in glioma cells through the ROCK-FAK pathway. ( Chen, Y; Chou, WC; Ding, YM; Wu, YC, 2014) |
| "We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk." | 3.78 | Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study. ( Darefsky, AS; Dubrow, R; Freedman, ND; Hollenbeck, AR; Sinha, R, 2012) |
| "To elucidate the mechanisms of the intracellular signal transduction elicited with bradykinin in NG108-15 neuroblastoma x glioma hybrid cells, we examined the activation of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) by bradykinin stimulation." | 3.68 | Activation of Ca2+/calmodulin-dependent protein kinase II by stimulation with bradykinin in neuroblastoma x glioma hybrid NG108-15 cells. ( Fukunaga, K; Higashida, H; Miyamoto, E; Yamakawa, T, 1992) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 1.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "In vitro, caffeine treatment reduced glioma cell proliferation through G(0)/G(1)-phase cell cycle arrest by suppressing Rb phosphorylation." | 1.37 | Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. ( Cho, GJ; Cho, YW; Choi, J; Choi, WS; Jeong, JY; Kang, SS; Kim, HJ; Kim, JS; Ku, BM; Lee, YK; Roh, GS; Ryu, J, 2011) |
| "Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect." | 1.36 | Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. ( Giovannucci, E; Holick, CN; Michaud, DS; Smith, SG, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JC | 2 |
| Hwang, JH | 2 |
| Chiu, WH | 1 |
| Chan, YC | 1 |
| Chen, Y | 2 |
| Chou, WC | 1 |
| Ding, YM | 2 |
| Wu, YC | 1 |
| Cheng, YC | 1 |
| Hueng, DY | 1 |
| Chen, JY | 1 |
| Holick, CN | 1 |
| Smith, SG | 1 |
| Giovannucci, E | 1 |
| Michaud, DS | 1 |
| Sinn, B | 1 |
| Tallen, G | 1 |
| Schroeder, G | 1 |
| Grassl, B | 1 |
| Schulze, J | 1 |
| Budach, V | 1 |
| Tinhofer, I | 1 |
| Ku, BM | 1 |
| Lee, YK | 1 |
| Jeong, JY | 1 |
| Ryu, J | 1 |
| Choi, J | 1 |
| Kim, JS | 1 |
| Cho, YW | 1 |
| Roh, GS | 1 |
| Kim, HJ | 1 |
| Cho, GJ | 1 |
| Choi, WS | 1 |
| Kang, SS | 1 |
| Dubrow, R | 1 |
| Darefsky, AS | 1 |
| Freedman, ND | 1 |
| Hollenbeck, AR | 1 |
| Sinha, R | 1 |
| Golding, SE | 1 |
| Rosenberg, E | 1 |
| Khalil, A | 1 |
| McEwen, A | 1 |
| Holmes, M | 1 |
| Neill, S | 1 |
| Povirk, LF | 1 |
| Valerie, K | 1 |
| Nakamura, H | 1 |
| Volpe, JJ | 1 |
| Jeng, I | 1 |
| Klemm, N | 1 |
| Tolkovsky, AM | 1 |
| Rouzaire-Dubois, B | 2 |
| Bostel, S | 2 |
| Dubois, JM | 2 |
| Borbé, R | 1 |
| Rieger, J | 1 |
| Weller, M | 1 |
| Saqr, HE | 1 |
| Guan, Z | 1 |
| Yates, AJ | 1 |
| Stokes, BT | 1 |
| Rondé, P | 1 |
| Dougherty, JJ | 1 |
| Nichols, RA | 1 |
| Malo, M | 1 |
| Yamakawa, T | 1 |
| Fukunaga, K | 1 |
| Higashida, H | 1 |
| Miyamoto, E | 1 |
| Vartanian, LP | 2 |
| Kolesova, MB | 1 |
| Krutovskikh, GN | 1 |
| Gornaeva, GF | 1 |
| Girshovich, MZ | 1 |
| Rudenko, IIa | 1 |
| Volchkov, VA | 1 |
| Stewart, DJ | 1 |
| Hugenholtz, H | 1 |
| DaSilva, V | 1 |
| Benoit, B | 1 |
| Richard, M | 1 |
| Russell, N | 1 |
| Maroun, J | 1 |
| Verma, S | 1 |
1 review available for caffeine and Glioma
| Article | Year |
|---|---|
[Liposomal boron delivery system for neutron capture therapy].
Topics: Animals; Boron Neutron Capture Therapy; Brain Neoplasms; Caffeine; Chlorpheniramine; Codeine; Drug C | 2008 |
21 other studies available for caffeine and Glioma
| Article | Year |
|---|---|
Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats.
Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Caffeine; Cell Line, Tumor; Endoplasmic Reticulum St | 2022 |
Tetrandrine and caffeine modulated cell cycle and increased glioma cell death via caspase-dependent and caspase-independent apoptosis pathways.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; Benzylisoquin | 2014 |
Caffeine inhibits migration in glioma cells through the ROCK-FAK pathway.
Topics: Amides; Animals; Blotting, Western; Caffeine; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell S | 2014 |
Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Brain Neoplasms; Caffeine; Cathepsin | 2016 |
Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies.
Topics: Adult; Aged; Brain Neoplasms; Caffeine; Coffee; Cohort Studies; Diet; Female; Glioma; Humans; Male; | 2010 |
Caffeine confers radiosensitization of PTEN-deficient malignant glioma cells by enhancing ionizing radiation-induced G1 arrest and negatively regulating Akt phosphorylation.
Topics: Animals; Brain Neoplasms; Caffeine; Cell Line, Tumor; Cell Survival; DNA Damage; G1 Phase; Gene Expr | 2010 |
Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2011 |
Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study.
Topics: Aged; Brain Neoplasms; Caffeine; Carbonated Beverages; Coffee; Cohort Studies; Female; Glioma; Human | 2012 |
Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells.
Topics: Adenoviridae; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Caffeine; Cell Cycle; Cell | 2004 |
Effects of methylxanthines on lipid synthesis in developing neural systems.
Topics: Acetyl-CoA Carboxylase; Aging; Aminophylline; Brain; Caffeine; Cell Division; Cell Line; Cholesterol | 1981 |
Stimulation of fatty acid release in glioblastoma cells by caffeine.
Topics: Arachidonic Acid; Arachidonic Acids; Biological Transport; Caffeine; Cells, Cultured; Fatty Acids; G | 1984 |
2'-Deoxyadenosine functionally uncouples adenylate cyclase from the guanyl nucleotide subunit without altering simultaneous GppNHp occupancy.
Topics: Adenosine; Adenylyl Cyclases; Animals; Caffeine; Cell Line; Cell Membrane; Deoxyadenosines; Enzyme A | 1980 |
Evidence for several mechanisms of volume regulation in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Animals; Caffeine; Cell Size; Chloride Channels; Culture Media; Egtazic Acid; Glioma; Hybrid Cells; | 1999 |
Failure of taxol-based combination chemotherapy for malignant glioma cannot be overcome by G2/M checkpoint abrogators or altering the p53 status.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; G2 Phase; Genes, p53; Gli | 1999 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium | 1999 |
Functional IP3- and ryanodine-sensitive calcium stores in presynaptic varicosities of NG108-15 (rodent neuroblastoma x glioma hybrid) cells.
Topics: Animals; Bradykinin; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Glioma; Hybrid Cells; Ino | 2000 |
Calcium and voltage-dependent alterations of cell volume in neuroblastomaxglioma hybrid NG108-15 cells.
Topics: Brain Neoplasms; Caffeine; Calcimycin; Calcium; Cell Size; Chloride Channels; Electric Stimulation; | 2002 |
Activation of Ca2+/calmodulin-dependent protein kinase II by stimulation with bradykinin in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Bradykinin; Caffeine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Drug Interactions; Egta | 1992 |
[Proxyphein chemotherapy in experimental glioma of the brain in rats].
Topics: Animals; Brain Neoplasms; Caffeine; Glioma; Rats; Time Factors | 1990 |
[The radiation therapy of experimental brain tumors by using the radiosensitizing preparation xanthobin (8-bromocaffeine)].
Topics: Animals; Brain Neoplasms; Caffeine; Drug Evaluation, Preclinical; Glioma; Metronidazole; Neoplasm Tr | 1989 |
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; Carmustine; Cisplatin; Cy | 1987 |