caffeine has been researched along with Glial Cell Tumors in 22 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 8.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
| "Viability, cell cycle distribution, and expressions of eukaryotic translation initiation factor-2α (eIF-2α), cyclin D1, poly(ADP-ribose) polymerase 1 (PARP-1), and apoptosis-inducing factor (AIF) of RT-2 glioma cells were assayed under treatment of tetrandrine and caffeine for 48 h." | 7.80 | Tetrandrine and caffeine modulated cell cycle and increased glioma cell death via caspase-dependent and caspase-independent apoptosis pathways. ( Chan, YC; Chen, JC; Chiu, WH; Hwang, JH, 2014) |
| "Caffeine decreased the migration of rat C6 and human U87MG glioma cells and down-regulated the expression of phosphorylated focal adhesion kinase (p-FAK) and p-paxillin." | 7.80 | Caffeine inhibits migration in glioma cells through the ROCK-FAK pathway. ( Chen, Y; Chou, WC; Ding, YM; Wu, YC, 2014) |
| "We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk." | 7.78 | Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study. ( Darefsky, AS; Dubrow, R; Freedman, ND; Hollenbeck, AR; Sinha, R, 2012) |
| "To elucidate the mechanisms of the intracellular signal transduction elicited with bradykinin in NG108-15 neuroblastoma x glioma hybrid cells, we examined the activation of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) by bradykinin stimulation." | 7.68 | Activation of Ca2+/calmodulin-dependent protein kinase II by stimulation with bradykinin in neuroblastoma x glioma hybrid NG108-15 cells. ( Fukunaga, K; Higashida, H; Miyamoto, E; Yamakawa, T, 1992) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 5.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "In vitro, caffeine treatment reduced glioma cell proliferation through G(0)/G(1)-phase cell cycle arrest by suppressing Rb phosphorylation." | 5.37 | Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. ( Cho, GJ; Cho, YW; Choi, J; Choi, WS; Jeong, JY; Kang, SS; Kim, HJ; Kim, JS; Ku, BM; Lee, YK; Roh, GS; Ryu, J, 2011) |
| "Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect." | 5.36 | Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. ( Giovannucci, E; Holick, CN; Michaud, DS; Smith, SG, 2010) |
| "Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 4.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
| "Viability, cell cycle distribution, and expressions of eukaryotic translation initiation factor-2α (eIF-2α), cyclin D1, poly(ADP-ribose) polymerase 1 (PARP-1), and apoptosis-inducing factor (AIF) of RT-2 glioma cells were assayed under treatment of tetrandrine and caffeine for 48 h." | 3.80 | Tetrandrine and caffeine modulated cell cycle and increased glioma cell death via caspase-dependent and caspase-independent apoptosis pathways. ( Chan, YC; Chen, JC; Chiu, WH; Hwang, JH, 2014) |
| "Caffeine decreased the migration of rat C6 and human U87MG glioma cells and down-regulated the expression of phosphorylated focal adhesion kinase (p-FAK) and p-paxillin." | 3.80 | Caffeine inhibits migration in glioma cells through the ROCK-FAK pathway. ( Chen, Y; Chou, WC; Ding, YM; Wu, YC, 2014) |
| "We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk." | 3.78 | Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study. ( Darefsky, AS; Dubrow, R; Freedman, ND; Hollenbeck, AR; Sinha, R, 2012) |
| "To elucidate the mechanisms of the intracellular signal transduction elicited with bradykinin in NG108-15 neuroblastoma x glioma hybrid cells, we examined the activation of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) by bradykinin stimulation." | 3.68 | Activation of Ca2+/calmodulin-dependent protein kinase II by stimulation with bradykinin in neuroblastoma x glioma hybrid NG108-15 cells. ( Fukunaga, K; Higashida, H; Miyamoto, E; Yamakawa, T, 1992) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 1.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "In vitro, caffeine treatment reduced glioma cell proliferation through G(0)/G(1)-phase cell cycle arrest by suppressing Rb phosphorylation." | 1.37 | Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. ( Cho, GJ; Cho, YW; Choi, J; Choi, WS; Jeong, JY; Kang, SS; Kim, HJ; Kim, JS; Ku, BM; Lee, YK; Roh, GS; Ryu, J, 2011) |
| "Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect." | 1.36 | Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. ( Giovannucci, E; Holick, CN; Michaud, DS; Smith, SG, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JC | 2 |
| Hwang, JH | 2 |
| Chiu, WH | 1 |
| Chan, YC | 1 |
| Chen, Y | 2 |
| Chou, WC | 1 |
| Ding, YM | 2 |
| Wu, YC | 1 |
| Cheng, YC | 1 |
| Hueng, DY | 1 |
| Chen, JY | 1 |
| Holick, CN | 1 |
| Smith, SG | 1 |
| Giovannucci, E | 1 |
| Michaud, DS | 1 |
| Sinn, B | 1 |
| Tallen, G | 1 |
| Schroeder, G | 1 |
| Grassl, B | 1 |
| Schulze, J | 1 |
| Budach, V | 1 |
| Tinhofer, I | 1 |
| Ku, BM | 1 |
| Lee, YK | 1 |
| Jeong, JY | 1 |
| Ryu, J | 1 |
| Choi, J | 1 |
| Kim, JS | 1 |
| Cho, YW | 1 |
| Roh, GS | 1 |
| Kim, HJ | 1 |
| Cho, GJ | 1 |
| Choi, WS | 1 |
| Kang, SS | 1 |
| Dubrow, R | 1 |
| Darefsky, AS | 1 |
| Freedman, ND | 1 |
| Hollenbeck, AR | 1 |
| Sinha, R | 1 |
| Golding, SE | 1 |
| Rosenberg, E | 1 |
| Khalil, A | 1 |
| McEwen, A | 1 |
| Holmes, M | 1 |
| Neill, S | 1 |
| Povirk, LF | 1 |
| Valerie, K | 1 |
| Nakamura, H | 1 |
| Volpe, JJ | 1 |
| Jeng, I | 1 |
| Klemm, N | 1 |
| Tolkovsky, AM | 1 |
| Rouzaire-Dubois, B | 2 |
| Bostel, S | 2 |
| Dubois, JM | 2 |
| Borbé, R | 1 |
| Rieger, J | 1 |
| Weller, M | 1 |
| Saqr, HE | 1 |
| Guan, Z | 1 |
| Yates, AJ | 1 |
| Stokes, BT | 1 |
| Rondé, P | 1 |
| Dougherty, JJ | 1 |
| Nichols, RA | 1 |
| Malo, M | 1 |
| Yamakawa, T | 1 |
| Fukunaga, K | 1 |
| Higashida, H | 1 |
| Miyamoto, E | 1 |
| Vartanian, LP | 2 |
| Kolesova, MB | 1 |
| Krutovskikh, GN | 1 |
| Gornaeva, GF | 1 |
| Girshovich, MZ | 1 |
| Rudenko, IIa | 1 |
| Volchkov, VA | 1 |
| Stewart, DJ | 1 |
| Hugenholtz, H | 1 |
| DaSilva, V | 1 |
| Benoit, B | 1 |
| Richard, M | 1 |
| Russell, N | 1 |
| Maroun, J | 1 |
| Verma, S | 1 |
1 review available for caffeine and Glial Cell Tumors
| Article | Year |
|---|---|
[Liposomal boron delivery system for neutron capture therapy].
Topics: Animals; Boron Neutron Capture Therapy; Brain Neoplasms; Caffeine; Chlorpheniramine; Codeine; Drug C | 2008 |
21 other studies available for caffeine and Glial Cell Tumors
| Article | Year |
|---|---|
Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats.
Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Caffeine; Cell Line, Tumor; Endoplasmic Reticulum St | 2022 |
Tetrandrine and caffeine modulated cell cycle and increased glioma cell death via caspase-dependent and caspase-independent apoptosis pathways.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; Benzylisoquin | 2014 |
Caffeine inhibits migration in glioma cells through the ROCK-FAK pathway.
Topics: Amides; Animals; Blotting, Western; Caffeine; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell S | 2014 |
Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Brain Neoplasms; Caffeine; Cathepsin | 2016 |
Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies.
Topics: Adult; Aged; Brain Neoplasms; Caffeine; Coffee; Cohort Studies; Diet; Female; Glioma; Humans; Male; | 2010 |
Caffeine confers radiosensitization of PTEN-deficient malignant glioma cells by enhancing ionizing radiation-induced G1 arrest and negatively regulating Akt phosphorylation.
Topics: Animals; Brain Neoplasms; Caffeine; Cell Line, Tumor; Cell Survival; DNA Damage; G1 Phase; Gene Expr | 2010 |
Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2011 |
Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study.
Topics: Aged; Brain Neoplasms; Caffeine; Carbonated Beverages; Coffee; Cohort Studies; Female; Glioma; Human | 2012 |
Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells.
Topics: Adenoviridae; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Caffeine; Cell Cycle; Cell | 2004 |
Effects of methylxanthines on lipid synthesis in developing neural systems.
Topics: Acetyl-CoA Carboxylase; Aging; Aminophylline; Brain; Caffeine; Cell Division; Cell Line; Cholesterol | 1981 |
Stimulation of fatty acid release in glioblastoma cells by caffeine.
Topics: Arachidonic Acid; Arachidonic Acids; Biological Transport; Caffeine; Cells, Cultured; Fatty Acids; G | 1984 |
2'-Deoxyadenosine functionally uncouples adenylate cyclase from the guanyl nucleotide subunit without altering simultaneous GppNHp occupancy.
Topics: Adenosine; Adenylyl Cyclases; Animals; Caffeine; Cell Line; Cell Membrane; Deoxyadenosines; Enzyme A | 1980 |
Evidence for several mechanisms of volume regulation in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Animals; Caffeine; Cell Size; Chloride Channels; Culture Media; Egtazic Acid; Glioma; Hybrid Cells; | 1999 |
Failure of taxol-based combination chemotherapy for malignant glioma cannot be overcome by G2/M checkpoint abrogators or altering the p53 status.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; G2 Phase; Genes, p53; Gli | 1999 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium | 1999 |
Functional IP3- and ryanodine-sensitive calcium stores in presynaptic varicosities of NG108-15 (rodent neuroblastoma x glioma hybrid) cells.
Topics: Animals; Bradykinin; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Glioma; Hybrid Cells; Ino | 2000 |
Calcium and voltage-dependent alterations of cell volume in neuroblastomaxglioma hybrid NG108-15 cells.
Topics: Brain Neoplasms; Caffeine; Calcimycin; Calcium; Cell Size; Chloride Channels; Electric Stimulation; | 2002 |
Activation of Ca2+/calmodulin-dependent protein kinase II by stimulation with bradykinin in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Bradykinin; Caffeine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Drug Interactions; Egta | 1992 |
[Proxyphein chemotherapy in experimental glioma of the brain in rats].
Topics: Animals; Brain Neoplasms; Caffeine; Glioma; Rats; Time Factors | 1990 |
[The radiation therapy of experimental brain tumors by using the radiosensitizing preparation xanthobin (8-bromocaffeine)].
Topics: Animals; Brain Neoplasms; Caffeine; Drug Evaluation, Preclinical; Glioma; Metronidazole; Neoplasm Tr | 1989 |
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; Carmustine; Cisplatin; Cy | 1987 |