caffeine has been researched along with Fatty Liver in 25 studies
Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we analysed in the rat a model of fatty liver induced by administration of caffeine." | 7.68 | Lipid peroxidation in fatty liver induced by caffeine in rats. ( Biocca, ME; Canuto, RA; Dianzani, MU; Muzio, G, 1991) |
| "Severe NAFLD appeared with higher Kleiner scores." | 5.40 | Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring. ( Chen, L; Huang, H; Liu, Y; Liu, Z; Ping, J; Shen, L; Wang, H; Wang, L; Wu, Y; Zhang, L, 2014) |
| "The association of CC with nonalcoholic fatty liver disease (NAFLD) has not been established." | 5.38 | Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis. ( Calcagno, CJ; Harrison, SA; Jones, FJ; Molloy, JW; Torres, DM; Williams, CD, 2012) |
| "Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of metabolic syndrome, is the most common cause of primary liver disease." | 5.38 | Caffeine is protective in patients with non-alcoholic fatty liver disease. ( Birerdinc, A; Pawloski, L; Stepanova, M; Younossi, ZM, 2012) |
| "The treatment with caffeine in the rats fed the high-carbohydrate, high-fat diet decreased body fat and systolic blood pressure, improved glucose tolerance and insulin sensitivity, and attenuated cardiovascular and hepatic abnormalities, although the plasma lipid concentrations were further increased." | 5.38 | Caffeine attenuates metabolic syndrome in diet-induced obese rats. ( Brown, L; Kauter, K; Panchal, SK; Ward, LC; Wong, WY, 2012) |
| "The CBT was applied to 48 patients with NAFLD." | 5.37 | Non-invasive estimation of liver fibrosis in non-alcoholic fatty liver disease using the 13 C-caffeine breath test. ( Fung, C; George, J; Katelaris, PH; Ngu, MC; Park, GJ; Seow, F; Wiseman, E, 2011) |
| " Caffeine has anti-inflammation, antihepatic steatosis, and anti-insulin resistance effects." | 3.88 | Effects and mechanisms of caffeine to improve immunological and metabolic abnormalities in diet-induced obese rats. ( Hou, MC; Hsieh, YC; Huang, CC; Huang, SF; Lee, FY; Lee, KC; Lee, SD; Li, TH; Lin, HC; Lin, MW; Liu, CW; Su, YB; Tsai, CY; Tsai, HC; Yang, YY, 2018) |
| " In this study we analysed in the rat a model of fatty liver induced by administration of caffeine." | 3.68 | Lipid peroxidation in fatty liver induced by caffeine in rats. ( Biocca, ME; Canuto, RA; Dianzani, MU; Muzio, G, 1991) |
| "Obesity, non-alcoholic fatty liver and steatohepatitis as well as diabetes mellitus together also form a significant risk for HCC, due to the gradually increasing number of patients." | 2.46 | [Role of environmental factors in the etiology of hepatocellular carcinoma]. ( Tornai, I, 2010) |
| "Caffeine was not associated significantly with LSM at any dose." | 1.72 | Coffee Consumption Is Associated With Lower Liver Stiffness: A Nationally Representative Study. ( Jiang, ZG; Mehta, M; Niezen, S; Tapper, EB, 2022) |
| "Caffeine elimination was accelerated by microvesicular steatosis, whereas midazolam elimination was delayed in macrovesicular steatosis." | 1.72 | Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism. ( Albadry, M; Böttcher, M; Christ, B; Christ, M; Dahmen, U; Dirsch, O; Ehteshamzad, N; Höpfl, S; Klopfleisch, R; König, M; Laue, H; Lupp, A; Neumann, J; Radde, N; Schwen, LO, 2022) |
| "Severe NAFLD appeared with higher Kleiner scores." | 1.40 | Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring. ( Chen, L; Huang, H; Liu, Y; Liu, Z; Ping, J; Shen, L; Wang, H; Wang, L; Wu, Y; Zhang, L, 2014) |
| "The association of CC with nonalcoholic fatty liver disease (NAFLD) has not been established." | 1.38 | Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis. ( Calcagno, CJ; Harrison, SA; Jones, FJ; Molloy, JW; Torres, DM; Williams, CD, 2012) |
| "Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of metabolic syndrome, is the most common cause of primary liver disease." | 1.38 | Caffeine is protective in patients with non-alcoholic fatty liver disease. ( Birerdinc, A; Pawloski, L; Stepanova, M; Younossi, ZM, 2012) |
| "The treatment with caffeine in the rats fed the high-carbohydrate, high-fat diet decreased body fat and systolic blood pressure, improved glucose tolerance and insulin sensitivity, and attenuated cardiovascular and hepatic abnormalities, although the plasma lipid concentrations were further increased." | 1.38 | Caffeine attenuates metabolic syndrome in diet-induced obese rats. ( Brown, L; Kauter, K; Panchal, SK; Ward, LC; Wong, WY, 2012) |
| "The CBT was applied to 48 patients with NAFLD." | 1.37 | Non-invasive estimation of liver fibrosis in non-alcoholic fatty liver disease using the 13 C-caffeine breath test. ( Fung, C; George, J; Katelaris, PH; Ngu, MC; Park, GJ; Seow, F; Wiseman, E, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 17 (68.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niezen, S | 1 |
| Mehta, M | 1 |
| Jiang, ZG | 1 |
| Tapper, EB | 1 |
| Albadry, M | 2 |
| Höpfl, S | 2 |
| Ehteshamzad, N | 2 |
| König, M | 2 |
| Böttcher, M | 2 |
| Neumann, J | 2 |
| Lupp, A | 2 |
| Dirsch, O | 2 |
| Radde, N | 2 |
| Christ, B | 2 |
| Christ, M | 2 |
| Schwen, LO | 3 |
| Laue, H | 2 |
| Klopfleisch, R | 2 |
| Dahmen, U | 2 |
| Liu, CW | 1 |
| Tsai, HC | 1 |
| Huang, CC | 1 |
| Tsai, CY | 1 |
| Su, YB | 1 |
| Lin, MW | 1 |
| Lee, KC | 1 |
| Hsieh, YC | 1 |
| Li, TH | 1 |
| Huang, SF | 1 |
| Yang, YY | 1 |
| Hou, MC | 1 |
| Lin, HC | 1 |
| Lee, FY | 1 |
| Lee, SD | 1 |
| Sinha, RA | 1 |
| Farah, BL | 1 |
| Singh, BK | 1 |
| Siddique, MM | 1 |
| Li, Y | 1 |
| Wu, Y | 2 |
| Ilkayeva, OR | 1 |
| Gooding, J | 1 |
| Ching, J | 1 |
| Zhou, J | 1 |
| Martinez, L | 1 |
| Xie, S | 1 |
| Bay, BH | 1 |
| Summers, SA | 1 |
| Newgard, CB | 1 |
| Yen, PM | 1 |
| Saab, S | 1 |
| Mallam, D | 1 |
| Cox, GA | 1 |
| Tong, MJ | 1 |
| Wang, L | 1 |
| Shen, L | 1 |
| Ping, J | 1 |
| Zhang, L | 1 |
| Liu, Z | 1 |
| Liu, Y | 1 |
| Huang, H | 1 |
| Chen, L | 1 |
| Wang, H | 1 |
| Zheng, G | 1 |
| Qiu, Y | 1 |
| Zhang, QF | 1 |
| Li, D | 1 |
| Chirumbolo, S | 1 |
| Schenk, A | 1 |
| Kreutz, C | 1 |
| Timmer, J | 1 |
| Bartolomé Rodríguez, MM | 1 |
| Kuepfer, L | 1 |
| Preusser, T | 1 |
| Salomone, F | 1 |
| Galvano, F | 1 |
| Li Volti, G | 1 |
| Yun, JW | 1 |
| Shin, ES | 1 |
| Cho, SY | 1 |
| Kim, SH | 1 |
| Kim, CW | 1 |
| Lee, TR | 1 |
| Kim, BH | 1 |
| Yamauchi, R | 1 |
| Kobayashi, M | 1 |
| Matsuda, Y | 1 |
| Ojika, M | 1 |
| Shigeoka, S | 1 |
| Yamamoto, Y | 1 |
| Tou, Y | 1 |
| Inoue, T | 1 |
| Katagiri, T | 1 |
| Murai, A | 1 |
| Horio, F | 1 |
| Tornai, I | 1 |
| Park, GJ | 1 |
| Wiseman, E | 1 |
| George, J | 1 |
| Katelaris, PH | 1 |
| Seow, F | 1 |
| Fung, C | 1 |
| Ngu, MC | 1 |
| Molloy, JW | 1 |
| Calcagno, CJ | 1 |
| Williams, CD | 1 |
| Jones, FJ | 1 |
| Torres, DM | 1 |
| Harrison, SA | 1 |
| Birerdinc, A | 1 |
| Stepanova, M | 1 |
| Pawloski, L | 1 |
| Younossi, ZM | 1 |
| Panchal, SK | 2 |
| Poudyal, H | 1 |
| Waanders, J | 1 |
| Brown, L | 2 |
| Carrieri, MP | 1 |
| Sogni, P | 1 |
| Cohen, J | 1 |
| Loko, MA | 1 |
| Winnock, M | 1 |
| Spire, B | 1 |
| Wong, WY | 1 |
| Kauter, K | 1 |
| Ward, LC | 1 |
| Anty, R | 1 |
| Marjoux, S | 1 |
| Iannelli, A | 1 |
| Patouraux, S | 1 |
| Schneck, AS | 1 |
| Bonnafous, S | 1 |
| Gire, C | 1 |
| Amzolini, A | 1 |
| Ben-Amor, I | 1 |
| Saint-Paul, MC | 1 |
| Mariné-Barjoan, E | 1 |
| Pariente, A | 1 |
| Gugenheim, J | 1 |
| Gual, P | 1 |
| Tran, A | 1 |
| Schmilovitz-Weiss, H | 1 |
| Niv, Y | 1 |
| Pappo, O | 1 |
| Halpern, M | 1 |
| Sulkes, J | 1 |
| Braun, M | 1 |
| Barak, N | 1 |
| Rotman, Y | 1 |
| Cohen, M | 1 |
| Waked, A | 1 |
| Tur-Kaspa, R | 1 |
| Ben-Ari, Z | 1 |
| Zetterman, RK | 1 |
| Leevy, CM | 1 |
| Dianzani, MU | 1 |
| Muzio, G | 1 |
| Biocca, ME | 1 |
| Canuto, RA | 1 |
| Strubelt, O | 1 |
| Wegener, F | 1 |
| Siegers, CP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inter Cohorts and Clinical Centres Collaborations of Subjects Co-infected With Hepatitis C and Human Immunodeficiency Virus (Collaboration Inter Cohortes et Centres Cliniques de Sujets Co-infectés Par Les Virus de l'immunodéficence Humaine et de l'hépatit[NCT03324633] | 1,850 participants (Actual) | Observational | 2005-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for caffeine and Fatty Liver
| Article | Year |
|---|---|
Impact of coffee on liver diseases: a systematic review.
Topics: Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Caffeine; Carcinoma, Hepatocell | 2014 |
Molecular Bases Underlying the Hepatoprotective Effects of Coffee.
Topics: Animals; Caffeine; Chlorogenic Acid; Coffee; Disease Models, Animal; Fatty Liver; Humans; Lipid Meta | 2017 |
[Role of environmental factors in the etiology of hepatocellular carcinoma].
Topics: Aflatoxins; Alcohol Drinking; Antioxidants; Caffeine; Carcinoma, Hepatocellular; Coffee; Contracepti | 2010 |
Immunologic reactivity and alcoholic liver disease.
Topics: Acetaldehyde; Alcoholism; Antigen-Antibody Reactions; B-Lymphocytes; Caffeine; Chemical and Drug Ind | 1975 |
Alcohol: another intoxicating instalment.
Topics: Alcohol Oxidoreductases; Animals; Barbiturates; Caffeine; Drug Incompatibility; Ethanol; Fatty Liver | 1970 |
20 other studies available for caffeine and Fatty Liver
| Article | Year |
|---|---|
Coffee Consumption Is Associated With Lower Liver Stiffness: A Nationally Representative Study.
Topics: Adult; Beverages; Caffeine; Coffee; Fatty Liver; Humans; Nutrition Surveys; Tea | 2022 |
Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism.
Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Fatty Liver; Metabolic Clearance Rate; Mice; Mida | 2022 |
Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism.
Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Fatty Liver; Metabolic Clearance Rate; Mice; Mida | 2022 |
Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism.
Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Fatty Liver; Metabolic Clearance Rate; Mice; Mida | 2022 |
Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism.
Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Fatty Liver; Metabolic Clearance Rate; Mice; Mida | 2022 |
Effects and mechanisms of caffeine to improve immunological and metabolic abnormalities in diet-induced obese rats.
Topics: Adiposity; Animals; Caffeine; Cells, Cultured; Diet, High-Fat; Fatty Liver; Immune System Diseases; | 2018 |
Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.
Topics: Animals; Autophagy; Caffeine; Cell Line, Tumor; Diet, High-Fat; Down-Regulation; Fatty Liver; Hep G2 | 2014 |
Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring.
Topics: Algorithms; Animals; Blood Glucose; Body Weight; Caffeine; Central Nervous System Stimulants; Fatty | 2014 |
Chlorogenic acid and caffeine in combination inhibit fat accumulation by regulating hepatic lipid metabolism-related enzymes in mice.
Topics: Acyl-CoA Oxidase; Adiposity; Animals; Caffeine; Carnitine Acyltransferases; Chlorogenic Acid; Dietar | 2014 |
In vivo anti-diabetic potential of chlorogenic acid as a consequence of synergism with other phenolic compounds?
Topics: Animals; Caffeine; Chlorogenic Acid; Dietary Supplements; Fatty Liver; Female; Gene Expression Regul | 2015 |
Representative Sinusoids for Hepatic Four-Scale Pharmacokinetics Simulations.
Topics: Adult; Animals; Blood Circulation; Caffeine; Fatty Liver; Humans; Insulin; Liver; Male; Mice; Models | 2015 |
The effects of BADGE and caffeine on the time-course response of adiponectin and lipid oxidative enzymes in high fat diet-fed C57BL/6J mice: correlation with reduced adiposity and steatosis.
Topics: Acetyl-CoA Carboxylase; Adiponectin; Animals; Biphenyl Compounds; Caffeine; Carnitine O-Palmitoyltra | 2008 |
Coffee and caffeine ameliorate hyperglycemia, fatty liver, and inflammatory adipocytokine expression in spontaneously diabetic KK-Ay mice.
Topics: Adipokines; Animals; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Experimental; Fatty Liver; | 2010 |
Non-invasive estimation of liver fibrosis in non-alcoholic fatty liver disease using the 13 C-caffeine breath test.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Biopsy; Breath Tests; Caffeine; Case-Control S | 2011 |
Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis.
Topics: Age Factors; Alanine Transaminase; Body Mass Index; Caffeine; Coffee; Fatty Liver; Female; Glycated | 2012 |
Caffeine is protective in patients with non-alcoholic fatty liver disease.
Topics: Adult; Aged; Aged, 80 and over; Caffeine; Diet; Fatty Liver; Female; Humans; Liver; Male; Middle Age | 2012 |
Coffee extract attenuates changes in cardiovascular and hepatic structure and function without decreasing obesity in high-carbohydrate, high-fat diet-fed male rats.
Topics: Animals; Anti-Obesity Agents; Caffeine; Coffee; Diet, High-Fat; Dietary Sucrose; Diterpenes; Fatty L | 2012 |
Elevated coffee consumption and reduced risk of insulin resistance in HIV-HCV coinfected patients (HEPAVIH ANRS CO-13).
Topics: Caffeine; Coffee; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Male | 2012 |
Caffeine attenuates metabolic syndrome in diet-induced obese rats.
Topics: Adipose Tissue; Animals; Blood Pressure; Caffeine; Cardiovascular System; Diet, High-Fat; Dietary Ca | 2012 |
Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery.
Topics: Adult; Bariatric Surgery; Biopsy; Cacao; Caffeine; Coffee; Cohort Studies; Cola; Comorbidity; Europe | 2012 |
The 13C-caffeine breath test detects significant fibrosis in patients with nonalcoholic steatohepatitis.
Topics: Breath Tests; Caffeine; Carbon Isotopes; Diagnosis, Differential; Fatty Liver; Female; Follow-Up Stu | 2008 |
Lipid peroxidation in fatty liver induced by caffeine in rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Fatty Liver; Lipid Peroxidation; Male; Rats; | 1991 |
[Hepatotoxicity of caffeine and theophylline].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeine; Carbon Tetrachloride Poisoning | 1970 |