Page last updated: 2024-10-24

caffeine and Diathesis

caffeine has been researched along with Diathesis in 128 studies

Research Excerpts

ExcerptRelevanceReference
"The most commonly used laboratory test for predicting malignant hyperthermia susceptibility is the caffeine halothane contracture test."9.07Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry. ( Bunn, JS; Diaz, M; Landis, JR; Larach, MG, 1992)
" We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH."7.69Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia. ( Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N, 1995)
"5 g/l in drinking water) on bicuculline- and pentylenetetrazol (PTZ)-induced seizures and c-fos expression were studied in mice."7.69Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding. ( Fredholm, BB; Georgiev, V; Johansson, B; Kuosmanen, T, 1996)
"Two strains of inbred mice differed significantly in their susceptibility to tonic seizures induced by caffeine and the benzodiazepine inverse agonist, methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM)."7.67Different genes specify hyporesponsiveness to seizures induced by caffeine and the benzodiazepine inverse agonist, DMCM. ( Abla, KA; Carney, JM; Rennert, OM; Roderick, TH; Seale, TW, 1987)
"The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome."7.67Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests. ( Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D, 1987)
"Occurrence of seizures following long-term oral administration of caffeine (0."5.35Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine. ( Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM, 2008)
"The most commonly used laboratory test for predicting malignant hyperthermia susceptibility is the caffeine halothane contracture test."5.07Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry. ( Bunn, JS; Diaz, M; Landis, JR; Larach, MG, 1992)
"The thermogenic effect of an over-the-counter preparation containing 22 mg ephedrine, 30 mg caffeine and 50 mg theophylline was investigated in human volunteers with a predisposition to obesity and also in the lean."5.06The thermogenic properties of ephedrine/methylxanthine mixtures: human studies. ( Dulloo, AG; Miller, DS, 1986)
" However, experts worldwide agree that the only reference test to this day remains the in vitro halothane caffeine contracture tests."4.77[Screening tests for malignant hyperthermia susceptibility]. ( Adnet, P; Krivosic-Horber, R, 1989)
" Diagnosis is based on in vitro muscle contracture in response to halothane and/or caffeine exposure."3.70[Malignant hyperthermia susceptibility in 3 patients with malignant neuroleptic syndrome]. ( Bahia, VS; Marchiori, PE; Oliveira, RA; Scaff, M; Silva, HC; Tsanaclis, AM, 2000)
"5 g/l in drinking water) on bicuculline- and pentylenetetrazol (PTZ)-induced seizures and c-fos expression were studied in mice."3.69Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding. ( Fredholm, BB; Georgiev, V; Johansson, B; Kuosmanen, T, 1996)
" We evaluated whether toxic concentrations of cocaine altered the in vitro muscle response to halothane during contracture tests for MH."3.69Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia. ( Brum, JM; DeBoer, GE; Mitsumoto, H; Sato, N, 1995)
" The halothane/caffeine contracture test was performed on the biopsied muscle."3.69Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy. ( Britt, BA; Carr, AS; Cunliffe, M; Lerman, J; McLeod, ME, 1995)
"Early developmental exposure to caffeine in rats results in decreased susceptibility to certain chemically-induced seizures in the adult."3.69Neonatal caffeine exposure alters seizure susceptibility in rats in an age-related manner. ( Guillet, R, 1995)
"The in vitro contracture test determines the sensitivity of freshly obtained skeletal muscle specimens to caffeine or halothane applied to a bathing solution."3.68In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update. ( Gallagher, WJ; Iaizzo, PA; Wedel, DJ, 1991)
" In vitro, human MHS muscle samples were exposed to propofol and changes in (a) baseline tension and (b) contracture tension on exposure to halothane and caffeine were measured."3.68Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients. ( Couchman, KG; McKenzie, AJ; Pollock, N, 1992)
"The in vitro halothane and caffeine contracture tests have been performed on muscle tissue from six survivors of the neuroleptic malignant syndrome."3.67Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests. ( Adnet, P; Guevart, E; Krivosic-Horber, R; Lestavel, P; Theunynck, D, 1987)
" The in vitro halothane-caffeine contracture tests are the most reliable method of identifying individuals susceptible to MH."3.67The association between the neuroleptic malignant syndrome and malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Adnet-Bonte, CA; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Saulnier, F, 1989)
"Two strains of inbred mice differed significantly in their susceptibility to tonic seizures induced by caffeine and the benzodiazepine inverse agonist, methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM)."3.67Different genes specify hyporesponsiveness to seizures induced by caffeine and the benzodiazepine inverse agonist, DMCM. ( Abla, KA; Carney, JM; Rennert, OM; Roderick, TH; Seale, TW, 1987)
" Halothane-caffeine contracture tests, interpreted in accordance with the criteria of the European Group on Malignant Hyperthermia, yielded the following results: 13 positive (MHS), 10 negative (MHN), 4 equivocal (MHE)."3.67[Tests of contracture and sensitivity to malignant hyperthermia in 27 patients]. ( Adamantidis, M; Adnet, P; Guévart, E; Krivosic, I; Krivosic-Horber, R; Theunynck, D, 1988)
"Patients with malignant hyperthermia susceptibility were classified into subgroups HH and HS (positive to halothane only and positive to both caffeine and halothane)."1.91Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia. ( Figueroa, L; Ibarra-Moreno, CA; Kraeva, N; Manno, C; Riazi, S; Rios, E; Tammineni, ER, 2023)
"The variable clinical presentation of malignant hyperthermia (MH), a disorder of calcium signalling, hinders its diagnosis and management."1.51Abnormal calcium signalling and the caffeine-halothane contracture test. ( Figueroa, L; Kraeva, N; Manno, C; Riazi, S; Ríos, E; Toro, S, 2019)
"To diagnose malignant hyperthermia (MH) susceptibility, muscle bundles are exposed to halothane and caffeine."1.37Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study. ( Anetseder, M; Hartung, E; Metterlein, T; Roewer, N; Schuster, F, 2011)
"In vitro contracture testing to diagnose malignant hyperthermia (MH) susceptibility requires a muscle biopsy, which may be associated with severe side effects for the patient."1.35An in-vivo metabolic test for detecting malignant hyperthermia susceptibility in humans: a pilot study. ( Anetseder, M; Kranke, P; Metterlein, T; Muellenbach, RM; Negele, S; Roewer, N; Schuster, F; Schwemmer, U, 2008)
"In order to unveil long-lasting catalepsy refractoriness not attributable to the presence of caffeine in the brains of rats, they were evaluated from day 18 to day 27 after caffeine withdrawal, a time that is far in excess for the full excretion of a caffeine dose in this species."1.35Long-lasting resistance to haloperidol-induced catalepsy in male rats chronically treated with caffeine. ( Alvarez-Cervera, FJ; Bata-García, JL; Góngora-Alfaro, JL; Heredia-López, FJ; Moo-Puc, RE; Pineda, JC; Villanueva-Toledo, JR, 2009)
"Occurrence of seizures following long-term oral administration of caffeine (0."1.35Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine. ( Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM, 2008)
" MH susceptibility leads to a leftward shift of the dose-response curve for IM lactate after local injection of halothane and caffeine."1.33The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs. ( Anetseder, M; Hager, M; Müller, R; Roewer, N; Schöll, H; Schuster, F, 2006)
"Susceptibility to malignant hyperthermia is diagnosed by contracture test, which requires an open muscle biopsy sample."1.31Diagnosis of susceptibility to malignant hyperthermia by use of a metabolic test. ( Anetseder, M; Hager, M; Müller, CR; Roewer, N, 2002)
"These results suggest that human malignant hyperthermia (MH) is associated with reduced inhibition of the RYR by (i) cytosolic Mg(2+) and (ii) SR Ca(2+) depletion."1.31Effects of Mg(2+) and SR luminal Ca(2+) on caffeine-induced Ca(2+) release in skeletal muscle from humans susceptible to malignant hyperthermia. ( Duke, AM; Hopkins, PM; Steele, DS, 2002)
"The association between malignant hyperthermia (MH) and neuromuscular disorders is controversial."1.30Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study. ( Bittner, RE; Gilly, H; Mader, N, 1997)
"Chlorocresol was demonstrated to be a potent activator of Ca++ release from skeletal muscle sarcoplasmic reticulum."1.30[Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients]. ( Adnet, PJ; Ben-Abraham, R; Haudcoeur, G; Krivosic-Horber, RM; Perel, A, 1997)
" The type of fibres (type I: oxidative, slow; type II: glycolytic, fast) were determined with strontium dose-response curves."1.30[Caffeine skinned fiber tension test: application to the diagnosis of susceptibility to malignant hyperthermia]. ( Adnet, P; Börtlein, ML; Etchrivi, T; Haudecoeur, G; Krivosic-Horber, R; Nivoche, Y; Tavernier, B, 1999)
" MHEh muscles revealed a dose-response curve similar to that found in MHN specimens."1.30Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol. ( Bittner, RE; Fricker, R; Gilly, H; Kress, HG; Musat, I; Steinbereithner, K, 1997)
"Caffeine sensitivity was defined as the threshold concentration inducing more than 10% of the maximal tension obtained with a calcium 1."1.29Fiber-type caffeine sensitivities in skinned muscle fibers from humans susceptible to malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Bello, N; Bromberg, NL; Haudecoeur, G; Krivosic Horber, RM; Krivosic, I; Reyford, H, 1993)
"The altered caffeine sensitivity of malignant hyperthermia-susceptible (MHS) muscle contracture is one basis of the diagnostic test for this syndrome."1.29Caffeine stimulation of malignant hyperthermia-susceptible sarcoplasmic reticulum Ca2+ release channel. ( Louis, CF; Mickelson, JR; Shomer, NH, 1994)
"Caffeine sensitivity was studied in chemically skinned muscle fibers from vastus lateralis muscle obtained by biopsy during reconstructive knee surgery from 15 otherwise healthy young individuals."1.28Fiber-type specific caffeine sensitivities in normal human skinned muscle fibers. ( Andrish, JT; Bunge, G; Cruse, RP; DeBoer, GE; Mitsumoto, H; Tetzlaff, JE, 1990)
" In six MH(-) patients with previous masseter muscle rigidity, no adverse reactions occurred in response to volatile anesthetic agents."1.28Safety of general anesthesia in patients previously tested negative for malignant hyperthermia susceptibility. ( Allen, GC; Fletcher, JE; Rosenberg, H, 1990)
"Pre-treatment with ryanodine did not change the calcium signal brought about by halothane or ionomycin."1.28[Effects of halothane, caffeine and ryanodine on the intracellular calcium store in blood mononuclear cells]. ( Endo, M; Iino, M; Kawana, Y; Oyamada, H, 1992)
" In contrast, propranolol shifted the caffeine dose-response curve to the right and significantly increased the caffeine threshold in the MHS group."1.28Influence of propranolol on the in vitro response to caffeine and halothane in malignant hyperthermia-susceptible muscle. ( Ording, H, 1989)
"A European Malignant Hyperpyrexia Group has been formed to facilitate exchange of information between centres performing in vitro muscle testing for malignant hyperpyrexia susceptibility."1.27A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group. ( , 1984)
"The caffeine test was positive in 68% of MHS patients, 0."1.27Investigation of malignant hyperthermia in Denmark and Sweden. ( Fletcher, R; Ording, H; Ranklev, E, 1984)
"Malignant hyperthermia is a seemingly rare genetic myopathy."1.27Malignant hyperthermia in plastic surgery. ( Abdul-Rasool, IH; Dubrow, TJ; Lesavoy, MA; Wackym, PA, 1988)
"In vitro tests for the diagnosis of malignant hyperthermia susceptibility were performed in 105 patients and 20 normal controls according to the protocol of the European MH Group."1.27In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests. ( Ording, H; Skovgaard, LT, 1987)
"Ten additional patients had other muscle disorders (central core disease, hyperkalemic periodic paralysis, and Duchenne's muscular dystrophy) and abnormal IVCTs; six of the ten had elevated CK levels."1.27Serum creatine kinase level as a screening test for susceptibility to malignant hyperthermia. ( Brownell, AK; Paasuke, RT, 1986)
"The father was found to be malignant hyperpyrexia-susceptible."1.27Malignant hyperpyrexia and sudden death. ( Fletcher, R; Krantz, P; Ranklev, E, 1985)

Research

Studies (128)

TimeframeStudies, this research(%)All Research%
pre-199036 (28.13)18.7374
1990's61 (47.66)18.2507
2000's18 (14.06)29.6817
2010's9 (7.03)24.3611
2020's4 (3.13)2.80

Authors

AuthorsStudies
Carlson, KJ1
Sun, SA1
Swan, C1
Koenig, M1
Derkay, CS1
Figueroa, L2
Kraeva, N3
Manno, C2
Ibarra-Moreno, CA1
Tammineni, ER1
Riazi, S3
Rios, E2
Li, J1
Xiao, H1
Luo, H1
Tan, Y1
Ni, Q1
He, C1
Magdalou, J1
Chen, L1
Wang, H1
Sylvetsky, AC1
Visek, AJ1
Turvey, C1
Halberg, S1
Weisenberg, JR1
Lora, K1
Sacheck, J1
Thompson, SJ1
Noseworthy, MD1
Rayner, TE1
Schneiderman, JE1
Cifra, B1
Wells, GD1
Toro, S1
Silva, CG1
Métin, C1
Fazeli, W1
Machado, NJ1
Darmopil, S1
Launay, PS1
Ghestem, A1
Nesa, MP1
Bassot, E1
Szabó, E1
Baqi, Y1
Müller, CE1
Tomé, AR1
Ivanov, A1
Isbrandt, D1
Zilberter, Y1
Cunha, RA1
Esclapez, M1
Bernard, C1
Roesl, C1
Sato, K1
Schiemann, A1
Pollock, N2
Stowell, KM1
Sagui, E1
Montigon, C1
Abriat, A1
Jouvion, A1
Duron-Martinaud, S1
Canini, F2
Zagnoli, F1
Bendahan, D2
Figarella-Branger, D1
Brégigeon, M1
Brosset, C1
Faingold, CL1
Randall, M1
Kommajosyula, SP1
Hoppe, K1
Hack, G1
Lehmann-Horn, F5
Jurkat-Rott, K1
Wearing, S1
Zullo, A1
Carsana, A1
Klingler, W2
Schuster, F3
Metterlein, T2
Negele, S1
Kranke, P1
Muellenbach, RM1
Schwemmer, U1
Roewer, N7
Anetseder, M6
Silletta, MG1
Marchioli, R1
Góngora-Alfaro, JL1
Moo-Puc, RE1
Villanueva-Toledo, JR1
Alvarez-Cervera, FJ1
Bata-García, JL1
Heredia-López, FJ1
Pineda, JC1
Tchekalarova, J2
Kubová, H2
Mares, P2
Hartung, E3
Duke, AM1
Hopkins, PM6
Steele, DS1
Islander, G1
Ording, H8
Bendixen, D2
Ranklev Twetman, E1
Allen, PD1
López, JR1
Sei, Y1
Brandom, BW1
Bina, S2
Hosoi, E1
Gallagher, KL1
Wyre, HW1
Pudimat, PA1
Holman, SJ1
Venzon, DJ1
Daly, JW1
Muldoon, S2
Wappler, F3
Baur, CP1
Censier, K2
Doetsch, S1
Felleiter, P1
Fiege, M1
Fricker, R2
Halsall, PJ5
Heffron, JJ2
Heytens, L3
Nivoche, Y2
Tegazzin, V1
Tzanova, I1
Urwyler, A3
Weisshorn, R1
Schulte am Esch, J3
Baker, PS1
Textor, Z1
Beer, M1
Köstler, H1
Kagerbauer, E1
Kenn, W1
Hahn, D1
MENGUY, R1
Ducreux, S1
Zorzato, F1
Müller, C1
Sewry, C1
Muntoni, F1
Quinlivan, R1
Restagno, G1
Girard, T1
Treves, S1
Litman, RS1
Rosenberg, H9
Schöll, H1
Hager, M2
Müller, R1
Bünger, R1
El Yacoubi, M1
Ledent, C1
Parmentier, M1
Costentin, J1
Vaugeois, JM1
Blanck, TJ1
Gruener, RP1
Ranklev, E4
Fletcher, R4
Reed, S1
Nelson, TE2
Flewellen, EH1
Gloyna, DF1
Steinfath, M1
Singh, S1
Scholz, J2
Becker, K1
Lenzen, C1
Köchling, A2
Sato, N1
Brum, JM1
Mitsumoto, H2
DeBoer, GE2
Bello, N2
Adnet, P6
Saulnier, F2
Lestavel, P2
Adnet-Bonte, C1
Reyford, H2
Etchrivi, T2
Tavernier, B3
Krivosic-Horber, R6
Carr, AS1
Lerman, J1
Cunliffe, M1
McLeod, ME1
Britt, BA2
Ducart, A1
Renaud, B1
Riou, B1
Shomer, NH1
Mickelson, JR1
Louis, CF1
O'Flynn, RP1
Shutack, JG1
Fletcher, JE5
Kaufmann, MA1
Drewe, J1
Adnet, PJ7
Krivosic-Horber, RM6
Krivosic, I3
Haudecoeur, G7
Reyford, HG1
Adamantidis, MM5
Medahoui, H1
Mortier, W1
Breucking, E1
Schrezenmeir, J1
Keppler, I1
Fenselau, S1
Weber, P1
Biesalski, HK1
Probst, R1
Laue, C1
Zuchhold, HD1
Prellwitz, W1
Beyer, J1
Bromberg, NL1
Krivosic Horber, RM1
Payen, JF1
Bosson, JL1
Bourdon, L2
Jacquot, C1
Le Bas, JF1
Stieglitz, P1
Benabid, AL1
Ellis, FR4
Guillet, R1
Serfas, KD1
Bose, D1
Patel, L1
Wrogemann, K1
Phillips, MS1
MacLennan, DH1
Greenberg, CR1
Sessler, DI1
Johansson, B1
Georgiev, V1
Kuosmanen, T1
Fredholm, BB1
Kozak-Ribbens, G1
Confort-Gouny, S1
Cozzone, PJ1
Stewart, AD1
O'Brien, PJ2
Li, G1
Weglinski, MR1
Wedel, DJ2
Engel, AG1
Gilly, H2
Musat, I1
Bittner, RE2
Steinbereithner, K3
Kress, HG1
Bachand, M1
Vachon, N1
Boisvert, M1
Mayer, FM1
Chartrand, D1
Ben-Abraham, R1
Haudcoeur, G1
Perel, A1
Mader, N1
Glahn, K1
Gardi, T1
Fagerlund, T1
Cipriani, F1
Geddes, M1
Ummenhofer, W1
Roesslein, R1
Sutter, PM1
Moser, N1
Kern, C1
Stewart, SH1
Karp, J1
Pihl, RO1
Peterson, RA1
Winkler, G1
Schulte am Esch, JS1
Etchrivi, TS1
Diallo, A1
Börtlein, ML1
Silva, HC1
Bahia, VS1
Oliveira, RA1
Marchiori, PE1
Scaff, M1
Tsanaclis, AM1
Pastera, J1
Anzenbacher, P1
Fiala, Z1
Müller, CR1
Cosgrove, SB1
Eisele, PH1
Martucci, RW2
Gronert, GA2
McKenzie, AJ1
Couchman, KG1
Kawana, Y1
Iino, M1
Oyamada, H1
Endo, M1
Reyford, GH1
Imbenotte, M1
Cordonnier, C1
Larach, MG2
Landis, JR1
Bunn, JS1
Diaz, M1
Martin, JJ1
Van de Kelft, E1
Bossaert, LL1
Olthoff, D1
Meinecke, CD1
Preis, I1
Engelhardt, W1
Krauspe, R1
Poels, PJ1
Joosten, EM1
Sengers, RC1
Stadhouders, AM1
Veerkamp, JH1
Benders, AA1
Iaizzo, PA4
Gallagher, WJ1
Rum, U1
Schmitz, W1
Scholz, H1
Seewald, MJ1
Eichinger, HM1
Jaffe, RS1
Elliott, TE1
Cardinet, GH1
Camu, F1
Olgin, J1
Allen, G1
Seestedt, R1
Chance, B1
Klip, A1
Mills, GB1
Elliott, ME1
Bunge, G1
Andrish, JT1
Tetzlaff, JE1
Cruse, RP1
Allen, GC2
Huggins, FJ1
Conti, PA1
Reyfort, GH1
Dupuis, BA2
Kalow, BI1
Ali, N1
Lassaline, LA1
Lumsden, JH1
Kadlubar, FF1
Talaska, G1
Butler, MA1
Teitel, CH1
Massengill, JP1
Lang, NP1
Wieland, SJ1
Gong, QH1
Adnet-Bonte, CA1
Foster, PS1
Hopkinson, KC1
Denborough, MA1
Hackl, W2
Winkler, M1
Mauritz, W2
Burket, RC1
Hodgin, JD1
Seale, TW1
Abla, KA1
Roderick, TH1
Rennert, OM1
Carney, JM1
Wackym, PA1
Dubrow, TJ1
Abdul-Rasool, IH1
Lesavoy, MA1
Theunynck, D2
Guévart, E2
Adamantidis, M1
Schreiber, GB1
Robins, M1
Maffeo, CE1
Masters, MN1
Bond, AP1
Morganstein, D1
Klein, W1
Sporn, P1
Graf, M1
Sluga, E1
Skovgaard, LT2
Blomquist, S1
Dulloo, AG1
Miller, DS1
Paasuke, RT1
Brownell, AK1
Gallant, EM1
Fletcher, TF1
Goettl, VM1
Rempel, WE1
Krantz, P1
Monti, M1
Ilias, WK1
Williams, CH1
Fulfer, RT1
Dozier, SE1
Fishbein, WN1
Muldoon, SM1
Deuster, PA1
Armbrustmacher, VW1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Freeman-Sheldon Syndrome Evaluation and Diagnosis in Clinical Settings (FSS-EDICT) I: a Case-Control, Cross-Sectional Study of Baseline and Stress Physiology Parameters[NCT01306994]0 participants (Actual)Observational2014-03-31Withdrawn (stopped due to Lack of patient interest)
Implication of Patient in the Making Ready of Recommendations for the Antivitamin K's Gestion in Case of Thrombosis Embolic Venous's Illness. Randomised Study for Clinical Validation.[NCT00227097]300 participants Observational2002-12-31Terminated
Evaluation of Diet and Treatment With a Combination of Ephedrine and Caffeine on Thermogenesis, Cardiac Function and on Uncoupling Proteins Expression in Adipose and Muscle Tissue of Morbid Obese Patients Undergoing Bariatric Surgery.[NCT02048215]Phase 313 participants (Actual)Interventional2000-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for caffeine and Diathesis

ArticleYear
[Coffee and cardiovascular disease risk: yin and yang].
    Recenti progressi in medicina, 2008, Volume: 99, Issue:11

    Topics: Caffeine; Cardiovascular Diseases; Cardiovascular System; Coffee; Confounding Factors, Epidemiologic

2008
Malignant hyperthermia.
    Biochemical pharmacology, 1983, Aug-01, Volume: 32, Issue:15

    Topics: Animals; Caffeine; Calcium; Cold Temperature; Creatine Kinase; Dantrolene; Disease Susceptibility; H

1983
[Etiological epidemiology of colorectal tumors].
    Annali dell'Istituto superiore di sanita, 1996, Volume: 32, Issue:4

    Topics: Alcohol Drinking; Caffeine; Cohort Studies; Colorectal Neoplasms; Diet; Disease Susceptibility; Etha

1996
[Screening tests for malignant hyperthermia susceptibility].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Animals; Caffeine; Calcium; Cholinesterases; Contracture; Creatine Kinase; Cyclic AMP; Disease Susce

1989
Standardization of the caffeine halothane muscle contracture test. North American Malignant Hyperthermia Group.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:4

    Topics: Biopsy; Caffeine; Clinical Laboratory Techniques; Disease Susceptibility; Halothane; Humans; Maligna

1989
Diagnosis of susceptibility to malignant hyperthermia in man.
    British journal of anaesthesia, 1988, Volume: 60, Issue:3

    Topics: Caffeine; Chemistry, Clinical; Disease Susceptibility; Halothane; Hematologic Tests; Humans; In Vitr

1988

Trials

5 trials available for caffeine and Diathesis

ArticleYear
Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:7

    Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant

2003
Caffeine impairs intramuscular energy balance in patients susceptible to malignant hyperthermia.
    Muscle & nerve, 2003, Volume: 28, Issue:3

    Topics: Adult; Age Factors; Caffeine; Calcium; Calcium Signaling; Disease Susceptibility; Female; Humans; In

2003
Prediction of malignant hyperthermia susceptibility in low-risk subjects. An epidemiologic investigation of caffeine halothane contracture responses. The North American Malignant Hyperthermia Registry.
    Anesthesiology, 1992, Volume: 76, Issue:1

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Female; Halot

1992
A blinded comparison of noninvasive, in vivo phosphorus nuclear magnetic resonance spectroscopy and the in vitro halothane/caffeine contracture test in the evaluation of malignant hyperthermia susceptibility.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Female; Halothane; Hum

1991
The thermogenic properties of ephedrine/methylxanthine mixtures: human studies.
    International journal of obesity, 1986, Volume: 10, Issue:6

    Topics: Adult; Basal Metabolism; Body Temperature Regulation; Caffeine; Calorimetry; Disease Susceptibility;

1986

Other Studies

117 other studies available for caffeine and Diathesis

ArticleYear
Management of patients susceptible to malignant hyperthermia: A surgeon's perspective.
    International journal of pediatric otorhinolaryngology, 2022, Volume: 159

    Topics: Caffeine; Child; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Retrospective St

2022
Distinct pathophysiological characteristics in developing muscle from patients susceptible to malignant hyperthermia.
    British journal of anaesthesia, 2023, Volume: 131, Issue:1

    Topics: Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contrac

2023
GR/HDAC2/TGFβR1 pathway contributes to prenatal caffeine induced-osteoarthritis susceptibility in male adult offspring rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 140

    Topics: Animals; Caffeine; Disease Susceptibility; Female; Histone Deacetylase 2; Male; Osteoarthritis; Preg

2020
Parental Concerns about Child and Adolescent Caffeinated Sugar-Sweetened Beverage Intake and Perceived Barriers to Reducing Consumption.
    Nutrients, 2020, Mar-25, Volume: 12, Issue:4

    Topics: Adolescent; Caffeine; Child; Child Behavior; Diet; Disease Susceptibility; Drinking Behavior; Feedin

2020
Skeletal Muscle Metabolic Dysfunction in Patients With Malignant Hyperthermia Susceptibility.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:2

    Topics: Adult; Anesthetics; Anthropometry; Caffeine; Case-Control Studies; Disease Susceptibility; Exercise

2017
Abnormal calcium signalling and the caffeine-halothane contracture test.
    British journal of anaesthesia, 2019, Volume: 122, Issue:1

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Calcium; Cells, Cultured; Disease Susceptibility; Dose-Res

2019
Adenosine receptor antagonists including caffeine alter fetal brain development in mice.
    Science translational medicine, 2013, Aug-07, Volume: 5, Issue:197

    Topics: Aging; Animals; Animals, Newborn; Brain; Caffeine; Cell Movement; Cognition Disorders; Disease Susce

2013
Functional characterisation of the R2452W ryanodine receptor variant associated with malignant hyperthermia susceptibility.
    Cell calcium, 2014, Volume: 56, Issue:3

    Topics: Blotting, Western; Caffeine; Calcium; Cells, Cultured; Central Nervous System Stimulants; Cresols; D

2014
Is there a link between exertional heat stroke and susceptibility to malignant hyperthermia?
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; He

2015
Susceptibility to seizure-induced sudden death in DBA/2 mice is altered by adenosine.
    Epilepsy research, 2016, Volume: 124

    Topics: Adenosine; Animals; Caffeine; Death, Sudden; Disease Models, Animal; Disease Susceptibility; Dose-Re

2016
Hypermetabolism in B-lymphocytes from malignant hyperthermia susceptible individuals.
    Scientific reports, 2016, 09-20, Volume: 6

    Topics: Adult; B-Lymphocytes; Biomarkers; Caffeine; Calcium; Cell Line, Transformed; Cresols; Disease Suscep

2016
An in-vivo metabolic test for detecting malignant hyperthermia susceptibility in humans: a pilot study.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:3

    Topics: Adult; Biopsy; Caffeine; Case-Control Studies; Disease Susceptibility; Female; Halothane; Humans; La

2008
Long-lasting resistance to haloperidol-induced catalepsy in male rats chronically treated with caffeine.
    Neuroscience letters, 2009, Oct-09, Volume: 463, Issue:3

    Topics: Animals; Caffeine; Catalepsy; Central Nervous System Stimulants; Disease Susceptibility; Dopamine D2

2009
Effects of early postnatal caffeine exposure on seizure susceptibility of rats are age- and model-dependent.
    Epilepsy research, 2010, Volume: 88, Issue:2-3

    Topics: Age Factors; Analysis of Variance; Animals; Caffeine; Convulsants; Disease Susceptibility; Dose-Resp

2010
Sevoflurane as a potential replacement for halothane in diagnostic testing for malignant hyperthermia susceptibility: results of a preliminary study.
    Minerva anestesiologica, 2011, Volume: 77, Issue:8

    Topics: Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility; Dose-R

2011
Effects of Mg(2+) and SR luminal Ca(2+) on caffeine-induced Ca(2+) release in skeletal muscle from humans susceptible to malignant hyperthermia.
    The Journal of physiology, 2002, Oct-01, Volume: 544, Issue:Pt 1

    Topics: Caffeine; Calcium; Disease Susceptibility; Humans; Magnesium; Malignant Hyperthermia; Muscle, Skelet

2002
Reproducibility of in vitro contracture test results in patients tested for malignant hyperthermia susceptibility.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:9

    Topics: Adult; Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans;

2002
"Noninvasive" testing for malignant hyperthermia susceptibility.
    Anesthesiology, 2002, Volume: 97, Issue:5

    Topics: Caffeine; Calcium; Cresols; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscl

2002
Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes.
    Anesthesiology, 2002, Volume: 97, Issue:5

    Topics: Adolescent; Adult; B-Lymphocytes; Caffeine; Calcium; Child; Cresols; Disease Susceptibility; Halotha

2002
Natural decaf could brew trouble for farmers.
    Nature, 2003, Aug-07, Volume: 424, Issue:6949

    Topics: Agriculture; Caffeine; Coffee; Disease Susceptibility; Plant Diseases; Plants, Genetically Modified

2003
[ETIOLOGY OF THE DUODENAL ULCER].
    Munchener medizinische Wochenschrift (1950), 1964, Mar-27, Volume: 106

    Topics: Aspirin; Caffeine; Disease Susceptibility; Duodenal Ulcer; Genetics, Medical; Humans; Hyperparathyro

1964
Effect of ryanodine receptor mutations on interleukin-6 release and intracellular calcium homeostasis in human myotubes from malignant hyperthermia-susceptible individuals and patients affected by central core disease.
    The Journal of biological chemistry, 2004, Oct-15, Volume: 279, Issue:42

    Topics: Caffeine; Calcium; Cells, Cultured; Cycloheximide; Cyclosporine; Disease Susceptibility; Homeostasis

2004
Malignant hyperthermia: update on susceptibility testing.
    JAMA, 2005, Jun-15, Volume: 293, Issue:23

    Topics: Algorithms; B-Lymphocytes; Biopsy; Caffeine; Disease Susceptibility; DNA Mutational Analysis; Haloth

2005
The dose-response relationship and regional distribution of lactate after intramuscular injection of halothane and caffeine in malignant hyperthermia-susceptible pigs.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Carbon Dioxide; Disease Susceptibility; Dose-Response Re

2006
Effects of postnatal caffeine exposure on seizure susceptibility in developing rats.
    Brain research, 2007, May-30, Volume: 1150

    Topics: Age Factors; Aminophylline; Animals; Animals, Newborn; Behavior, Animal; Bicuculline; Caffeine; Cent

2007
Effects of ryanodine on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:1

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Kinetics; Lactates; Malignant Hyperthermia; Mi

2008
Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine.
    Neuropharmacology, 2008, Volume: 55, Issue:1

    Topics: Analysis of Variance; Animals; Caffeine; Disease Models, Animal; Disease Susceptibility; Dose-Respon

2008
Investigation of malignant hyperthermia in Denmark and Sweden.
    British journal of anaesthesia, 1984, Volume: 56, Issue:11

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Female; G

1984
A protocol for the investigation of malignant hyperpyrexia (MH) susceptibility. The European Malignant Hyperpyrexia Group.
    British journal of anaesthesia, 1984, Volume: 56, Issue:11

    Topics: Biopsy; Caffeine; Disease Susceptibility; Genetic Testing; Halothane; Humans; In Vitro Techniques; M

1984
In vitro contracture tests for susceptibility to malignant hyperthermia.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:4

    Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; Malignant Hyperthermia; Musc

1983
Spectrum of susceptibility to malignant hyperthermia--diagnostic dilemma.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:6

    Topics: Animals; Body Temperature; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques;

1983
Abnormality in calcium release from skeletal sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:3

    Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Malignant Hyperthermia; Muscle Contraction; Musc

1983
C1840-T mutation in the human skeletal muscle ryanodine receptor gene: frequency in northern German families susceptible to malignant hyperthermia and the relationship to in vitro contracture response.
    Journal of molecular medicine (Berlin, Germany), 1995, Volume: 73, Issue:1

    Topics: Adolescent; Adult; Aged; Base Sequence; Caffeine; Calcium Channels; Child; Child, Preschool; Chromos

1995
Effect of cocaine on the contracture response to 1% halothane in patients undergoing diagnostic muscle biopsy for malignant hyperthermia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:2

    Topics: Adult; Biopsy; Caffeine; Cocaine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Ma

1995
[Lack of sensitivity to per-anesthetic malignant hyperthermia in 32 patients who developed neuroleptic malignant syndrome].
    Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Caffeine; Contracture; Creatine Kinase; Dantrolene; Di

1994
Incidence of malignant hyperthermia reactions in 2,214 patients undergoing muscle biopsy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Conduction; Anes

1995
Malignant hyperthermia during sevoflurane administration.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:3

    Topics: Adult; Anesthetics; Caffeine; Disease Susceptibility; Ethers; Female; Halothane; Humans; Malignant H

1995
Caffeine stimulation of malignant hyperthermia-susceptible sarcoplasmic reticulum Ca2+ release channel.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 1

    Topics: Animals; Caffeine; Calcium Channels; Disease Susceptibility; Electrophysiology; Hydrogen-Ion Concent

1994
Masseter muscle rigidity and malignant hyperthermia susceptibility in pediatric patients. An update on management and diagnosis.
    Anesthesiology, 1994, Volume: 80, Issue:6

    Topics: Adolescent; Biopsy; Caffeine; Child; Child, Preschool; Creatine Kinase; Disease Susceptibility; Fema

1994
Genetic effects on the variability of the halothane and caffeine muscle contracture tests.
    Anesthesiology, 1994, Volume: 80, Issue:6

    Topics: Adult; Biopsy; Caffeine; Child; Disease Susceptibility; Family; Fatal Outcome; Female; Halothane; Hu

1994
Viability criterion of muscle bundles used in the in vitro contracture test in patients with neuromuscular diseases.
    British journal of anaesthesia, 1994, Volume: 72, Issue:1

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Me

1994
[Diagnosis of malignant hyperthermia susceptibility. 1. The significance of in vitro susceptibility tests].
    Der Anaesthesist, 1993, Volume: 42, Issue:10

    Topics: Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In Vitro Techni

1993
The phenomenon of a high triglyceride response to an oral lipid load in healthy subjects and its link to the metabolic syndrome.
    Annals of the New York Academy of Sciences, 1993, Jun-14, Volume: 683

    Topics: Adult; Arteriosclerosis; Caffeine; Dietary Fats; Disease Susceptibility; Fasting; Fatty Acids; Human

1993
Fiber-type caffeine sensitivities in skinned muscle fibers from humans susceptible to malignant hyperthermia.
    Anesthesiology, 1993, Volume: 78, Issue:1

    Topics: Caffeine; Disease Susceptibility; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscles

1993
Improved noninvasive diagnostic testing for malignant hyperthermia susceptibility from a combination of metabolites determined in vivo with 31P-magnetic resonance spectroscopy.
    Anesthesiology, 1993, Volume: 78, Issue:5

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Disease Susceptibility; Female; Halothane; Humans; Magnet

1993
Comparison of in vitro contracture testing with ryanodine, halothane and caffeine in malignant hyperthermia and other neuromuscular disorders.
    British journal of anaesthesia, 1993, Volume: 70, Issue:4

    Topics: Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Tech

1993
On the nature of the link between malignant hyperthermia and exertional heatstroke.
    Medical hypotheses, 1995, Volume: 45, Issue:3

    Topics: Animals; Body Temperature Regulation; Caffeine; Calcium Channels; Disease Models, Animal; Disease Su

1995
Neonatal caffeine exposure alters seizure susceptibility in rats in an age-related manner.
    Brain research. Developmental brain research, 1995, Oct-27, Volume: 89, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Caffeine; Convulsants; Disease Susceptibilit

1995
Comparison of the segregation of the RYR1 C1840T mutation with segregation of the caffeine/halothane contracture test results for malignant hyperthermia susceptibility in a large Manitoba Mennonite family.
    Anesthesiology, 1996, Volume: 84, Issue:2

    Topics: Anesthetics, Inhalation; Caffeine; Disease Susceptibility; Female; Halothane; Heterozygote; Humans;

1996
Malignant hyperthermia.
    Acta anaesthesiologica Scandinavica. Supplementum, 1996, Volume: 109

    Topics: Anesthesia, General; Caffeine; Counseling; Disease Susceptibility; Halothane; Humans; Malignant Hype

1996
Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding.
    The European journal of neuroscience, 1996, Volume: 8, Issue:12

    Topics: Animals; Autoradiography; Behavior, Animal; Bicuculline; Brain; Caffeine; Disease Susceptibility; Ma

1996
[Definition of a diagnostic score of malignant hyperthermia using P-31 magnetic resonance spectroscopy].
    Annales francaises d'anesthesie et de reanimation, 1996, Volume: 15, Issue:5

    Topics: Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Magnetic Resonance Spectroscopy; M

1996
An analysis of the predictive probability of the in vitro contracture test for determining susceptibility to malignant hyperthermia.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:3

    Topics: Adolescent; Adult; Aged; Biopsy; Caffeine; Child; Contracture; Disease Susceptibility; Halothane; Hu

1997
Rapid, simple and sensitive microassay for skeletal muscle homogenates in the functional assessment of the Ca-release channel of sarcoplasmic reticulum: application to diagnosis of susceptibility to malignant hyperthermia.
    Molecular and cellular biochemistry, 1997, Volume: 167, Issue:1-2

    Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Disease Models, Animal;

1997
Malignant hyperthermia testing in patients with persistently increased serum creatine kinase levels.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:5

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Biopsy, Needle; Caffeine; Child; Child, Preschool; Clini

1997
Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Cresols; Disease Susceptibility; Dose-Re

1997
Clinical reassessment of malignant hyperthermia in Abitibi-Témiscamingue.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Caffeine; Child; Disease Susceptibility; Family Characteristics; Female; Halothan

1997
[Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients].
    Harefuah, 1997, Jun-15, Volume: 132, Issue:12

    Topics: Adolescent; Adult; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques

1997
Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study.
    British journal of anaesthesia, 1997, Volume: 79, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Caffeine; Disease Susceptibility; Dystrophin; Halothane; Male; Mal

1997
4-Chloro-m-cresol test--a possible supplementary test for diagnosis of malignant hyperthermia susceptibility.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:8

    Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Huma

1997
Muscle biopsy for malignant hyperthermia screening in children.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1997, Volume: 7, Issue:5

    Topics: Adolescent; Anesthetics, Inhalation; Biopsy; Caffeine; Central Nervous System Stimulants; Child; Dis

1997
Anxiety sensitivity and self-reported reasons for drug use.
    Journal of substance abuse, 1997, Volume: 9

    Topics: Adaptation, Psychological; Adolescent; Adult; Alcohol Drinking; Anxiety; Caffeine; Disease Susceptib

1997
Rhabdomyolysis following severe physical exercise in a patient with predisposition to malignant hyperthermia.
    Anaesthesia and intensive care, 1998, Volume: 26, Issue:3

    Topics: Adult; Anesthetics, Inhalation; Caffeine; Central Nervous System Stimulants; Disease Susceptibility;

1998
Effects of halothane on mechanical response of skeletal muscle from malignant hyperthermia susceptible patients.
    Archives of physiology and biochemistry, 1998, Volume: 106, Issue:4

    Topics: Anesthetics, Inhalation; Biopsy; Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techn

1998
[Caffeine skinned fiber tension test: application to the diagnosis of susceptibility to malignant hyperthermia].
    Annales francaises d'anesthesie et de reanimation, 1999, Volume: 18, Issue:6

    Topics: Caffeine; Disease Susceptibility; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contra

1999
[Malignant hyperthermia susceptibility in 3 patients with malignant neuroleptic syndrome].
    Arquivos de neuro-psiquiatria, 2000, Volume: 58, Issue:3A

    Topics: Adult; Caffeine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyp

2000
[Phenotyping of cytochrome P-450 1A2 and N-acetyltransferase (NAT2) using the in vivo caffeine test as a tool for determining individual susceptibility to selected xenobiotics].
    Acta medica (Hradec Kralove). Supplementum, 1999, Volume: 42, Issue:1

    Topics: Arylamine N-Acetyltransferase; Caffeine; Carcinogens; Chromatography, High Pressure Liquid; Cytochro

1999
Diagnosis of susceptibility to malignant hyperthermia by use of a metabolic test.
    Lancet (London, England), 2002, May-04, Volume: 359, Issue:9317

    Topics: Adult; Caffeine; Carbon Dioxide; Case-Control Studies; Disease Susceptibility; Female; Humans; Male;

2002
Evaluation of greyhound susceptibility to malignant hyperthermia using halothane-succinylcholine anesthesia and caffeine-halothane muscle contractures.
    Laboratory animal science, 1992, Volume: 42, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Caffeine; Disease Susceptibility; Dog Diseases; Dogs; Genetic Predi

1992
Is the "K-type" caffeine-halothane responder susceptible to malignant hyperthermia?
    British journal of anaesthesia, 1992, Volume: 69, Issue:5

    Topics: Caffeine; Culture Techniques; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Mus

1992
Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Caffeine; Contracture; Disease Susceptibility; Halothane

1992
[Effects of halothane, caffeine and ryanodine on the intracellular calcium store in blood mononuclear cells].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:5

    Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; Leukocytes, Mononuclear; Mali

1992
Evidence for related myopathies in exertional heat stroke and malignant hyperthermia.
    Lancet (London, England), 1991, Dec-14, Volume: 338, Issue:8781

    Topics: Adult; Biopsy; Caffeine; Disease Susceptibility; Family Health; Female; Halothane; Heat Exhaustion;

1991
Use of the calcium agonist BAY K 8644 for in vitro diagnosis of susceptibility to malignant hyperthermia.
    British journal of anaesthesia, 1990, Volume: 65, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
In vitro contracture tests in patients with various neuromuscular diseases.
    British journal of anaesthesia, 1992, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Aged; Caffeine; Child; Child, Preschool; Disease Susceptibility; Drug Hypersensit

1992
[A new emphasis on the diagnosis of malignant hyperthermia using the in vitro contracture test?].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1991, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Disease Susceptibility; Halothane; Humans; In

1991
[Diagnosis of malignant hyperthermia. The platelet test versus the in vitro contracture test].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1991, Volume: 26, Issue:8

    Topics: Blood Platelets; Caffeine; Child; Disease Susceptibility; Halothane; Humans; Male; Malignant Hyperth

1991
In vitro contraction test for malignant hyperthermia in patients with unexplained recurrent rhabdomyolysis.
    Journal of the neurological sciences, 1991, Volume: 105, Issue:1

    Topics: Adult; Caffeine; Calcium; Disease Susceptibility; Female; Halothane; Humans; Male; Malignant Hyperth

1991
In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodologic update.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:10

    Topics: Caffeine; Chromatography, Gas; Contracture; Diffusion Chambers, Culture; Disease Susceptibility; Ele

1991
Effects of caffeine, halothane, succinylcholine, phenylephrine and isoproterenol on myocardial force of contraction of malignant hyperthermia susceptible swine.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:4

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Isoproterenol; Malignant Hyperthermia; Myocard

1991
Characterization of swine susceptible to malignant hyperthermia by in vivo, in vitro and post-mortem techniques.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:4

    Topics: Administration, Inhalation; Animals; Caffeine; Creatine Kinase; Disease Susceptibility; Genotype; Ha

1991
Malignant hyperthermia: normal muscle calcium uptake and abnormal caffeine and halothane contractures.
    Anesthesiology, 1991, Volume: 75, Issue:3

    Topics: Adult; Biopsy; Caffeine; Calcium; Disease Susceptibility; False Negative Reactions; Female; Halothan

1991
The caffeine contracture test for malignant hyperthermia: caffeine citrate, caffeine benzoate or caffeine free base?
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:6

    Topics: Animals; Benzoates; Caffeine; Citrates; Disease Susceptibility; Drug Combinations; Male; Malignant H

1991
Halothane-dependent release of intracellular Ca2+ in blood cells in malignant hyperthermia.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 1

    Topics: Animals; Caffeine; Calcium; Cytosol; Disease Susceptibility; Egtazic Acid; Halothane; Humans; Malign

1990
Fiber-type specific caffeine sensitivities in normal human skinned muscle fibers.
    Anesthesiology, 1990, Volume: 72, Issue:1

    Topics: Adenosine Triphosphatases; Adolescent; Adult; Caffeine; Calcium; Child; Disease Susceptibility; Drug

1990
Are myotonias and periodic paralyses associated with susceptibility to malignant hyperthermia?
    British journal of anaesthesia, 1990, Volume: 65, Issue:5

    Topics: Biopsy; Caffeine; Calcium; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant

1990
Caffeine and halothane contracture testing in swine using the recommendations of the North American Malignant Hyperthermia Group.
    Anesthesiology, 1990, Volume: 72, Issue:1

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Malignant Hyperthermia; M

1990
Clinical concentrations of verapamil affect the in vitro diagnosis of susceptibility to malignant hyperpyrexia.
    British journal of anaesthesia, 1990, Volume: 64, Issue:1

    Topics: Caffeine; Disease Susceptibility; False Negative Reactions; Halothane; Humans; In Vitro Techniques;

1990
Safety of general anesthesia in patients previously tested negative for malignant hyperthermia susceptibility.
    Anesthesiology, 1990, Volume: 72, Issue:4

    Topics: Anesthesia, General; Caffeine; Contracture; Disease Susceptibility; Halothane; Humans; Malignant Hyp

1990
Current diagnostic methods of malignant hyperthermia: an evaluation.
    Acta anaesthesiologica Belgica, 1990, Volume: 41, Issue:2

    Topics: Caffeine; Chromosomes, Human, Pair 19; Disease Susceptibility; Halothane; Humans; Magnetic Resonance

1990
Compensatory increase in calcium extrusion activity of untreated lymphocytes from swine susceptible to malignant hyperthermia.
    American journal of veterinary research, 1990, Volume: 51, Issue:7

    Topics: Animals; Caffeine; Calcium; Disease Susceptibility; Halothane; Lymphocytes; Malignant Hyperthermia;

1990
Determination of carcinogenic arylamine N-oxidation phenotype in humans by analysis of caffeine urinary metabolites.
    Progress in clinical and biological research, 1990, Volume: 340B

    Topics: Acetylation; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Cytochrome P-450 Enzyme Sys

1990
Malignant hyperthermia: slow sodium current in cultured human muscle cells.
    The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 1

    Topics: Caffeine; Cells, Cultured; Disease Susceptibility; Electric Conductivity; Halothane; Humans; Maligna

1989
The association between the neuroleptic malignant syndrome and malignant hyperthermia.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:8

    Topics: Adult; Caffeine; Chlorpromazine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Mal

1989
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:10

    Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Mal

1989
[The action of ketamine on muscle contractile behavior. In vitro studies on the musculature of subjects susceptible to malignant hyperthermia].
    Der Anaesthesist, 1989, Volume: 38, Issue:12

    Topics: Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Ketamine; Malignant Hyperthermia;

1989
Fluoxetine treatment of a depressed patient susceptible to malignant hyperthermia.
    The American journal of psychiatry, 1989, Volume: 146, Issue:5

    Topics: Adolescent; Caffeine; Depressive Disorder; Disease Susceptibility; Female; Fluoxetine; Halothane; Hu

1989
Influence of propranolol on the in vitro response to caffeine and halothane in malignant hyperthermia-susceptible muscle.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:5

    Topics: Anesthesia; Caffeine; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; H

1989
Different genes specify hyporesponsiveness to seizures induced by caffeine and the benzodiazepine inverse agonist, DMCM.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:3

    Topics: Animals; Caffeine; Carbolines; Crosses, Genetic; Disease Susceptibility; Genes; Genetics, Behavioral

1987
Malignant hyperthermia in plastic surgery.
    Plastic and reconstructive surgery, 1988, Volume: 82, Issue:5

    Topics: Adult; Caffeine; Child; Child, Preschool; Dermoid Cyst; Disease Susceptibility; Facial Neoplasms; Fe

1988
[Tests of contracture and sensitivity to malignant hyperthermia in 27 patients].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Anesthesia, General; Biopsy; Caffeine; Child; Child, Preschool; Contracture; Crea

1988
Confounders contributing to the reported associations of coffee or caffeine with disease.
    Preventive medicine, 1988, Volume: 17, Issue:3

    Topics: Adult; Aged; Caffeine; Coffee; Coronary Disease; Disease Susceptibility; Drinking Behavior; Female;

1988
Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs.
    Pflugers Archiv : European journal of physiology, 1988, Volume: 411, Issue:6

    Topics: Animals; Benzofurans; Caffeine; Calcium; Disease Susceptibility; Fura-2; Halothane; Malignant Hypert

1988
[Malignant hyperthermia in Austria. II. A comparison of the results of diagnostic test procedures].
    Der Anaesthesist, 1988, Volume: 37, Issue:7

    Topics: Adult; Caffeine; Creatine Kinase; Disease Susceptibility; Electromyography; Female; Halothane; Human

1988
Neuroleptic malignant syndrome and malignant hyperthermia. In vitro comparison with halothane and caffeine contracture tests.
    British journal of anaesthesia, 1987, Volume: 59, Issue:12

    Topics: Adult; Aged; Caffeine; Disease Susceptibility; Female; Halothane; Humans; In Vitro Techniques; Male;

1987
In vitro diagnosis of susceptibility to malignant hyperthermia: evaluation of tests with halothane-caffeine, potassium chloride, suxamethonium and caffeine-suxamethonium.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:5

    Topics: Caffeine; Disease Susceptibility; Evaluation Studies as Topic; Halothane; Humans; In Vitro Technique

1987
In vitro diagnosis of susceptibility to malignant hyperthermia: comparison between dynamic and static halothane and caffeine tests.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:5

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Mu

1987
Static v. dynamic tests in the in vitro diagnosis of malignant hyperthermia susceptibility.
    British journal of anaesthesia, 1986, Volume: 58, Issue:6

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypertherm

1986
Malignant hyperthermia.
    Hospital practice (Office ed.), 1985, Mar-15, Volume: 20, Issue:3

    Topics: Adult; Anesthesia; Animals; Caffeine; Child; Creatine Kinase; Disease Susceptibility; Halothane; Hum

1985
Serum creatine kinase level as a screening test for susceptibility to malignant hyperthermia.
    JAMA, 1986, Feb-14, Volume: 255, Issue:6

    Topics: Biopsy; Caffeine; Clinical Enzyme Tests; Creatine Kinase; Disease Susceptibility; Humans; In Vitro T

1986
Porcine malignant hyperthermia: cell injury enhances halothane sensitivity of biopsies.
    Muscle & nerve, 1986, Volume: 9, Issue:2

    Topics: Animals; Caffeine; Disease Susceptibility; Halothane; Hybridization, Genetic; In Vitro Techniques; M

1986
Malignant hyperpyrexia and sudden death.
    The American journal of forensic medicine and pathology, 1985, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Caffeine; Death, Sudden; Disease Susceptibility; Halothane; Humans; Male; Maligna

1985
In vitro interaction between halothane and succinylcholine in human skeletal muscle: implications for malignant hyperthermia and masseter muscle rigidity.
    Anesthesiology, 1985, Volume: 63, Issue:2

    Topics: Caffeine; Disease Susceptibility; Drug Interactions; Halothane; Humans; In Vitro Techniques; Maligna

1985
Laboratory diagnosis of malignant hyperpyrexia susceptibility (MHS). European MH Group.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Caffeine; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia

1985
Microcalorimetric studies in malignant hyperpyrexia susceptible individuals.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Blood Platelets; Body Temperature Regulation; Caffeine; Calorimetry; Disease Susceptibility; Halotha

1985
Diltiazem inhibits halothane-induced contractions in malignant hyperthermia-susceptible muscles in vitro.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Animals; Benzazepines; Caffeine; Depression, Chemical; Diltiazem; Disease Susceptibility; Halothane;

1985
Myoadenylate deaminase deficiency and malignant hyperthermia susceptibility: is there a relationship?
    Biochemical medicine, 1985, Volume: 34, Issue:3

    Topics: Adenylate Kinase; Adult; AMP Deaminase; Caffeine; Creatine Kinase; Disease Susceptibility; Female; H

1985