caffeine has been researched along with Diabetes Mellitus, Type 1 in 26 studies
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate the effect of caffeine (in doses equivalent to normal daily ingestion) on rates and severity of hypoglycemia in patients with long-standing type 1 diabetes to determine the relationship between caffeine, autonomic function, and hypoglycemia." | 9.11 | Influence of caffeine on frequency of hypoglycemia detected by continuous interstitial glucose monitoring system in patients with long-standing type 1 diabetes. ( Kerr, D; Richardson, T; Ryder, J; Thomas, P, 2005) |
| "To examine the influence of caffeine on the frequency and perception of hypoglycemia in "free-living" patients with type 1 diabetes." | 9.09 | Influence of caffeine on the frequency and perception of hypoglycemia in free-living patients with type 1 diabetes. ( Hamilton, P; Jenkins, EJ; Kerr, D; Lunt, MJ; Watson, JM, 2000) |
| "Compounds other than macronutrients have been shown to influence blood glucose concentrations and insulin sensitivity in people with diabetes, with caffeine being one such substance." | 8.89 | Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013) |
| "The purpose was to determine the possible effects of exercise and/or caffeine on hypoglycemia and liver gluconeogenesis in diabetic rats." | 7.83 | Exercise partially reverses the inhibitory effect of caffeine on liver gluconeogenesis in type 1 diabetic rats with hypoglycemia. ( Bataglini, C; Berti, JA; Furlan, JP; Ghuidotti, CM; Gilglioni, EH; Godoi, V; Pedrosa, M; Vilela, VR, 2016) |
| "To test the hypothesis that, in women with type 1 diabetes, prenatal smoking and caffeine consumption during pregnancy are associated with an increased risk of adverse maternal and perinatal outcomes." | 7.72 | Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes. ( Buncher, CR; Kalkwarf, H; Khoury, JC; Khoury, PR; McElvy, S; Miodovnik, M; Sibai, B, 2004) |
| "Caffeine may increase an individual's sensitivity to hypoglycemia through the combined effects of reducing substrate delivery to the brain via constriction of the cerebral arteries, whilst simultaneously increasing brain glucose metabolism and augmenting catecholamine production." | 6.40 | The best defense against hypoglycemia is to recognize it: is caffeine useful? ( Kerr, D; Watson, J, 1999) |
| "The aim of this study was to investigate the effect of caffeine (in doses equivalent to normal daily ingestion) on rates and severity of hypoglycemia in patients with long-standing type 1 diabetes to determine the relationship between caffeine, autonomic function, and hypoglycemia." | 5.11 | Influence of caffeine on frequency of hypoglycemia detected by continuous interstitial glucose monitoring system in patients with long-standing type 1 diabetes. ( Kerr, D; Richardson, T; Ryder, J; Thomas, P, 2005) |
| "To examine the influence of caffeine on the frequency and perception of hypoglycemia in "free-living" patients with type 1 diabetes." | 5.09 | Influence of caffeine on the frequency and perception of hypoglycemia in free-living patients with type 1 diabetes. ( Hamilton, P; Jenkins, EJ; Kerr, D; Lunt, MJ; Watson, JM, 2000) |
| "Compounds other than macronutrients have been shown to influence blood glucose concentrations and insulin sensitivity in people with diabetes, with caffeine being one such substance." | 4.89 | Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013) |
| "The purpose was to determine the possible effects of exercise and/or caffeine on hypoglycemia and liver gluconeogenesis in diabetic rats." | 3.83 | Exercise partially reverses the inhibitory effect of caffeine on liver gluconeogenesis in type 1 diabetic rats with hypoglycemia. ( Bataglini, C; Berti, JA; Furlan, JP; Ghuidotti, CM; Gilglioni, EH; Godoi, V; Pedrosa, M; Vilela, VR, 2016) |
| "To test the hypothesis that, in women with type 1 diabetes, prenatal smoking and caffeine consumption during pregnancy are associated with an increased risk of adverse maternal and perinatal outcomes." | 3.72 | Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes. ( Buncher, CR; Kalkwarf, H; Khoury, JC; Khoury, PR; McElvy, S; Miodovnik, M; Sibai, B, 2004) |
| "A total of 13 patients with Type 1 diabetes [eight women, five men: mean ± sd age 25." | 2.82 | Effects of acute caffeine supplementation on reducing exercise-associated hypoglycaemia in individuals with Type 1 diabetes mellitus. ( Gumieniak, RJ; Jamnik, VK; Miadovnik, LA; Riddell, MC; Rowan, CP; Zaharieva, DP, 2016) |
| "The caffeine-associated increase in HRV was not statistically different between the control and the type 1 diabetes groups (P = 0." | 2.71 | Influence of caffeine on heart rate variability in patients with long-standing type 1 diabetes. ( Kerr, D; Meckes, C; Richardson, T; Rozkovec, A; Ryder, J; Thomas, P, 2004) |
| "Caffeine may increase an individual's sensitivity to hypoglycemia through the combined effects of reducing substrate delivery to the brain via constriction of the cerebral arteries, whilst simultaneously increasing brain glucose metabolism and augmenting catecholamine production." | 2.40 | The best defense against hypoglycemia is to recognize it: is caffeine useful? ( Kerr, D; Watson, J, 1999) |
| "Caffeine has recently been used to test liver function, but the effect of diabetes on caffeine kinetics is not known." | 1.28 | Pharmacokinetics of caffeine in patients with decompensated type I and type II diabetes mellitus. ( Wietholtz, H; Zysset, T, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (23.08) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 5 (19.23) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Devaraj, SM | 1 |
| Miller, RG | 2 |
| Orchard, TJ | 2 |
| Kriska, AM | 1 |
| Gary-Webb, T | 1 |
| Costacou, T | 2 |
| Olateju, T | 1 |
| Begley, J | 1 |
| Green, DJ | 1 |
| Kerr, D | 8 |
| Zaharieva, DP | 1 |
| Miadovnik, LA | 1 |
| Rowan, CP | 1 |
| Gumieniak, RJ | 1 |
| Jamnik, VK | 1 |
| Riddell, MC | 1 |
| Eny, KM | 1 |
| Maynard, J | 1 |
| Grant, DM | 1 |
| Cleary, PA | 1 |
| Braffett, BH | 1 |
| Paterson, AD | 1 |
| Gilglioni, EH | 1 |
| Ghuidotti, CM | 1 |
| Vilela, VR | 1 |
| Bataglini, C | 1 |
| Furlan, JP | 1 |
| Berti, JA | 1 |
| Pedrosa, M | 1 |
| Godoi, V | 1 |
| Whitehead, N | 1 |
| White, H | 1 |
| von Eyben, FE | 1 |
| Watson, JM | 2 |
| Sherwin, RS | 2 |
| Deary, IJ | 1 |
| Scott, L | 1 |
| SAPELKINA, LV | 1 |
| Khoury, JC | 1 |
| Miodovnik, M | 1 |
| Buncher, CR | 1 |
| Kalkwarf, H | 1 |
| McElvy, S | 1 |
| Khoury, PR | 1 |
| Sibai, B | 1 |
| Richardson, T | 2 |
| Rozkovec, A | 1 |
| Thomas, P | 2 |
| Ryder, J | 2 |
| Meckes, C | 1 |
| Sudano, I | 1 |
| Binggeli, C | 1 |
| Spieker, L | 1 |
| Lüscher, TF | 1 |
| Ruschitzka, F | 1 |
| Noll, G | 1 |
| Corti, R | 1 |
| Everett, J | 1 |
| Toh, V | 1 |
| Duncan, E | 1 |
| Lewis, N | 1 |
| Fichter, L | 1 |
| Matthews, DR | 1 |
| Debrah, K | 1 |
| Murphy, J | 1 |
| Korpinen, E | 1 |
| Groop, PH | 1 |
| Rautio, A | 1 |
| Madácsy, L | 1 |
| Reunanen, A | 1 |
| Vaarala, O | 1 |
| Akerblom, HK | 1 |
| Jenkins, EJ | 1 |
| Hamilton, P | 1 |
| Lunt, MJ | 1 |
| Watson, J | 1 |
| Zysset, T | 1 |
| Wietholtz, H | 1 |
| Tuomilehto, J | 1 |
| Tuomilehto-Wolf, E | 1 |
| Virtala, E | 1 |
| LaPorte, R | 1 |
| Denaro, C | 1 |
| Benowitz, N | 1 |
| Bechtel, YC | 1 |
| Joanne, C | 1 |
| Grandmottet, M | 1 |
| Bechtel, PR | 1 |
| Pedersen, O | 1 |
| Pagliara, AS | 1 |
| Karl, IE | 1 |
| Kipnis, DB | 1 |
| Paluszak, J | 1 |
| Walczak, M | 1 |
| Paluszak, W | 1 |
| Piontek, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Combined Caffeine and Carbohydrate Ingestion Counter the Exercise-mediated Fall in Glycaemia in Individuals With Type 1 Diabetes on Insulin Degludec? The DE-CAF Study[NCT04671043] | 21 participants (Actual) | Interventional | 2022-02-04 | Completed | |||
| Diabetes Control and Complications Trial (DCCT)[NCT00360815] | 1,441 participants | Interventional | 1983-08-31 | Completed | |||
| Epidemiology of Diabetes Interventions and Complications (EDIC)[NCT00360893] | 1,441 participants (Actual) | Observational | 1994-04-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for caffeine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus.
Topics: Beverages; Blood Glucose; Caffeine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, | 2013 |
Cardiovascular effects of coffee: is it a risk factor?
Topics: Blood Glucose; Caffeine; Cardiovascular System; Coffee; Cooking; Diabetes Mellitus, Type 1; Drinking | 2005 |
The best defense against hypoglycemia is to recognize it: is caffeine useful?
Topics: Adult; Awareness; Blood Glucose; Caffeine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Food Analys | 1999 |
Insulin receptor- and nonreceptor-controlled cellular substrate processing. A review of clinical studies in the isolated human adipocyte model.
Topics: 3-O-Methylglucose; Adipose Tissue; Biological Transport; Blood Cells; Caffeine; Cells, Cultured; Dia | 1985 |
7 trials available for caffeine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Effects of acute caffeine supplementation on reducing exercise-associated hypoglycaemia in individuals with Type 1 diabetes mellitus.
Topics: Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Combined Modality | 2016 |
Caffeine Consumption Contributes to Skin Intrinsic Fluorescence in Type 1 Diabetes.
Topics: Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Coffee; Diabetes Mellitus, Type 1; Femal | 2015 |
Caffeine Consumption Contributes to Skin Intrinsic Fluorescence in Type 1 Diabetes.
Topics: Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Coffee; Diabetes Mellitus, Type 1; Femal | 2015 |
Caffeine Consumption Contributes to Skin Intrinsic Fluorescence in Type 1 Diabetes.
Topics: Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Coffee; Diabetes Mellitus, Type 1; Femal | 2015 |
Caffeine Consumption Contributes to Skin Intrinsic Fluorescence in Type 1 Diabetes.
Topics: Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Coffee; Diabetes Mellitus, Type 1; Femal | 2015 |
Dissociation of augmented physiological, hormonal and cognitive responses to hypoglycaemia with sustained caffeine use.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Caffeine; Catecholamines; Central Nervous System Stimula | 2003 |
Influence of caffeine on heart rate variability in patients with long-standing type 1 diabetes.
Topics: Adult; Blood Pressure; Caffeine; Coffee; Cross-Over Studies; Diabetes Mellitus, Type 1; Female; Glyc | 2004 |
Influence of caffeine on frequency of hypoglycemia detected by continuous interstitial glucose monitoring system in patients with long-standing type 1 diabetes.
Topics: Adult; Blood Glucose; Blood Pressure; Caffeine; Central Nervous System Stimulants; Diabetes Mellitus | 2005 |
Effect of caffeine on recognition of and physiological responses to hypoglycaemia in insulin-dependent diabetes.
Topics: Adult; Blood Glucose; Brain; Caffeine; Cerebral Arteries; Cerebrovascular Circulation; Cognition; Di | 1996 |
Influence of caffeine on the frequency and perception of hypoglycemia in free-living patients with type 1 diabetes.
Topics: Adult; Blood Glucose; Blood Pressure; Caffeine; Cerebrovascular Circulation; Cognition; Cross-Over S | 2000 |
15 other studies available for caffeine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Data driven patterns of nutrient intake and coronary artery disease risk in adults with type 1 diabetes.
Topics: Adolescent; Adult; Caffeine; Child; Coronary Artery Disease; Diabetes Mellitus, Type 1; Eating; Ener | 2021 |
Physiological and glycemic responses following acute ingestion of a popular functional drink in patients with type 1 diabetes.
Topics: Adult; Affect; Blood Glucose; Blood Pressure; Caffeine; Cognition; Diabetes Mellitus, Type 1; Double | 2015 |
Exercise partially reverses the inhibitory effect of caffeine on liver gluconeogenesis in type 1 diabetic rats with hypoglycemia.
Topics: Animals; Caffeine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Down-Regulation; Gluc | 2016 |
[Obesity epidemic after Letigen].
Topics: Appetite Depressants; Caffeine; Central Nervous System Stimulants; Denmark; Diabetes Mellitus, Type | 2002 |
[GASTRIC SECRETION IN CHILDREN WITH DIABETES MELLITUS].
Topics: Adolescent; Caffeine; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Digestion; Gastric Acidit | 1964 |
Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes.
Topics: Abortion, Spontaneous; Adult; Birth Weight; Caffeine; Diabetes Mellitus, Type 1; Female; Humans; Pre | 2004 |
Coffee, diabetes and insulin sensitivity.
Topics: Adult; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Hyperg | 2005 |
Ergotamine use in severe diabetic autonomic neuropathy.
Topics: Aged; Caffeine; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Drug Combinations; Ergotamine; Hum | 2006 |
N-acetyltransferase-2 polymorphism, smoking and type 1 diabetic nephropathy.
Topics: Adult; Alleles; Arylamine N-Acetyltransferase; Base Sequence; Caffeine; Diabetes Mellitus, Type 1; D | 1999 |
Pharmacokinetics of caffeine in patients with decompensated type I and type II diabetes mellitus.
Topics: Adolescent; Adult; Aged; Caffeine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Mid | 1991 |
Coffee consumption as trigger for insulin dependent diabetes mellitus in childhood.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 1; Female; Finland; Humans; Maternal-Fetal Exchange; Pregn | 1990 |
Diabetic patients and hepatic drug metabolism.
Topics: Caffeine; Diabetes Mellitus, Type 1; Humans; Liver; Phenotype | 1989 |
The influence of insulin-dependent diabetes on the metabolism of caffeine and the expression of the debrisoquin oxidation phenotype.
Topics: Acetylation; Adult; Caffeine; Debrisoquin; Diabetes Mellitus, Type 1; Female; Humans; Isoquinolines; | 1988 |
Transient neonatal diabetes: delayed maturation of the pancreatic beta cell.
Topics: Adenylyl Cyclases; Blood Glucose; Caffeine; Cyclic AMP; Diabetes Mellitus, Type 1; Female; Glucose T | 1973 |
[Effect of caffeine on the lipid-mobilizing activity in diabetic children].
Topics: Administration, Oral; Adolescent; Adult; Caffeine; Child; Diabetes Mellitus, Type 1; Female; Humans; | 1974 |