caffeine has been researched along with Diabetes Mellitus, Adult-Onset in 131 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Randomized controlled trials (RCTs) that investigated the effect of caffeine on insulin sensitivity in healthy humans without diabetes were included." | 8.93 | Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: a systematic review and meta-analysis. ( Liang, S; Shi, X; Xue, W; Zhang, X; Zhao, J, 2016) |
| " Randomised controlled trials (RCTs) investigating the effects of caffeine on blood glucose and/or insulin sensitivity in humans, diagnosed with type I, type II or gestational diabetes mellitus (GDM), were included." | 8.89 | Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013) |
| " This review explores the relation between caffeine intake, diabetes, cognition and dementia, focusing on type 2 diabetes (T2DM)." | 8.86 | Caffeine, diabetes, cognition, and dementia. ( Biessels, GJ, 2010) |
| "The aim of this study was to assess the potential benefits of caffeine intake in protecting against the development of diabetic retinopathy (DR) in subjects with type 2 diabetes (T2D)." | 8.31 | Caffeine and the Risk of Diabetic Retinopathy in Type 2 Diabetes Mellitus: Findings from Clinical and Experimental Studies. ( Alcubierre, N; Bogdanov, P; Castelblanco, E; Granado-Casas, M; Hernández, C; Hernández, M; Jurjo, C; Mauricio, D; Navarrete-Muñoz, EM; Ramos, H; Real, J; Rubinat-Arnaldo, E; Simó, R; Traveset, A; Vioque, J, 2023) |
| "Caffeine consumption is associated with a substantial reduction in insulin-mediated glucose uptake independent of obesity, type 2 diabetes, and chronic exercise." | 7.73 | Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training. ( Graham, TE; Hudson, R; Kilpatrick, K; Lee, S; Ross, R, 2005) |
| "Non-alcoholic fatty liver disease (NAFLD) is much more frequent and more severe, including cirrhosis, hepatocellular carcinoma in patients with type 2 diabetes." | 7.01 | Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-c ( Adibi, H; Hekmatdoost, A; Mansour, A; Merat, S; Mohajeri-Tehrani, MR; Poustchi, H; Qorbani, M; Samadi, M, 2021) |
| "Pretreatment with caffeine to diabetic rats, resulted in improvement of structural changes and decrease in cytokine levels and immuno-markers, expression, and this was in a dose-dependent manner." | 5.91 | Caffeine protects against hippocampal alterations in type 2 diabetic rats via modulation of gliosis, inflammation and apoptosis. ( Al-Mahameed, AE; Fadel, R; Fatima, A; Jaradat, A; Nasr El-Din, WA; Othman, MA; Rashid, A; Tayem, Y, 2023) |
| "Cilostazol (CSZ) has been shown to be a new treatment for cognitive impairment with limited efficacy." | 5.72 | Advancing combination treatment with cilostazol and caffeine for Alzheimer's disease in high fat-high fructose-STZ induced model of amnesia. ( Ahmed, AM; El-Mokhtar, MA; Farghaly, HSM; Gomaa, AA; Hemida, FK, 2022) |
| "A 74-year-old man who had type 2 diabetes mellitus of a duration of 20 years was admitted for syncope after eating a high carbohydrate meal." | 5.56 | Prevention of postprandial hypotension-related syncope by caffeine in a patient with long-standing diabetes mellitus. ( Furukawa, K; Hanyu, O; Iijima, K; Ishiguro, H; Ito, M; Morikawa, H; Sone, H; Sonoda, K; Suzuki, T, 2020) |
| " The diabetes risk was negatively related to the consumption in a dose-response manner." | 5.33 | Coffee, tea and diabetes: the role of weight loss and caffeine. ( Axen, KV; Boozer, CN; Greenberg, JA; Schnoll, R, 2005) |
| "Caffeine ingestion negatively affects insulin sensitivity during an oral glucose tolerance test (OGTT) in lean and obese men, but this has not been studied in individuals with type 2 diabetes." | 5.11 | Caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetes. ( Battram, DS; Graham, TE; McLaren, DH; Robinson, LE; Sathasivam, P; Savani, S, 2004) |
| " Randomized controlled trials (RCTs) that investigated the effect of caffeine on insulin sensitivity in healthy humans without diabetes were included." | 4.93 | Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: a systematic review and meta-analysis. ( Liang, S; Shi, X; Xue, W; Zhang, X; Zhao, J, 2016) |
| " Randomised controlled trials (RCTs) investigating the effects of caffeine on blood glucose and/or insulin sensitivity in humans, diagnosed with type I, type II or gestational diabetes mellitus (GDM), were included." | 4.89 | Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013) |
| " This review explores the relation between caffeine intake, diabetes, cognition and dementia, focusing on type 2 diabetes (T2DM)." | 4.86 | Caffeine, diabetes, cognition, and dementia. ( Biessels, GJ, 2010) |
| " They also exist despite clear evidence showing that caffeine causes acute postprandial hyperglycemia and lower whole-body insulin sensitivity." | 4.84 | Coffee, glucose homeostasis, and insulin resistance: physiological mechanisms and mediators. ( Shearer, J; Tunnicliffe, JM, 2008) |
| "The aim of this study was to assess the potential benefits of caffeine intake in protecting against the development of diabetic retinopathy (DR) in subjects with type 2 diabetes (T2D)." | 4.31 | Caffeine and the Risk of Diabetic Retinopathy in Type 2 Diabetes Mellitus: Findings from Clinical and Experimental Studies. ( Alcubierre, N; Bogdanov, P; Castelblanco, E; Granado-Casas, M; Hernández, C; Hernández, M; Jurjo, C; Mauricio, D; Navarrete-Muñoz, EM; Ramos, H; Real, J; Rubinat-Arnaldo, E; Simó, R; Traveset, A; Vioque, J, 2023) |
| "We found no evidence that reduced risk of cognitive decline in women with high caffeine consumption is moderated or confounded by diabetes or depression." | 3.80 | The association between caffeine and cognitive decline: examining alternative causal hypotheses. ( Amieva, H; Ancelin, ML; Carrière, I; Ritchie, K; Rouaud, O, 2014) |
| "Maternal caffeine exposure may be one of the causes for intrauterine growth retardation and low birth weight (LBW), and increased risk of type 2 diabetes mellitus (T2DM) in the adulthood has been associated with LBW." | 3.80 | Maternal caffeine exposure impairs insulin secretion by pancreatic β-cells and increases the risk of type II diabetes mellitus in offspring. ( Chan, HC; Chen, H; Guo, J; Huang, X; Jiang, X; Sha, J; Sun, T; Wang, F; Xu, Z; Zhang, J; Zhang, X, 2014) |
| " Currently published data has been stressed that the metyloxantine consumption increases the risk of coronary heart disease, arterial hypertension, arterial stiffness, and an elevation of cholesterol and homocysteine plasma concentration." | 3.75 | [Side effects of caffeine]. ( Burdan, F; Dworzański, W; Opielak, G, 2009) |
| "Caffeine consumption is associated with a substantial reduction in insulin-mediated glucose uptake independent of obesity, type 2 diabetes, and chronic exercise." | 3.73 | Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training. ( Graham, TE; Hudson, R; Kilpatrick, K; Lee, S; Ross, R, 2005) |
| "Non-alcoholic fatty liver disease (NAFLD) is much more frequent and more severe, including cirrhosis, hepatocellular carcinoma in patients with type 2 diabetes." | 3.01 | Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-c ( Adibi, H; Hekmatdoost, A; Mansour, A; Merat, S; Mohajeri-Tehrani, MR; Poustchi, H; Qorbani, M; Samadi, M, 2021) |
| "Insulin sensitivity was higher with decaffeinated coffee than with water (P<0·05)." | 2.87 | Decaffeinated coffee improves insulin sensitivity in healthy men. ( Amato, AA; Bluck, LJC; da Costa, THM; Dórea, JG; Lofrano-Porto, A; Paiva, CLRDS; Reis, CEG; Wassell, S, 2018) |
| "Summary-level data for GERD were available from a genome-wide association meta-analysis of 71,522 GERD cases and 261,079 controls of European descent from the UK Biobank and QSkin Sun and Health studies." | 2.82 | Adiposity, diabetes, lifestyle factors and risk of gastroesophageal reflux disease: a Mendelian randomization study. ( Larsson, SC; Yuan, S, 2022) |
| "Caffeine intake was evaluated using questionnaires." | 2.82 | Caffeine intake enhances the benefits of sodium glucose transporter 2 inhibitor. ( Fukui, M; Hashimoto, Y; Nakamura, N; Nakano, K; Oda, Y; Okada, H; Tanaka, M; Ushigome, E; Yamazaki, M, 2016) |
| "Obesity is a worldwide prevalent metabolic disorder that is associated with diabetes, among many other diseases." | 2.66 | Attenuation of Weight Gain and Prevention of Associated Pathologies by Inhibiting SSAO. ( Deng, Y; Papukashvili, D; Rcheulishvili, N, 2020) |
| " Inhibiting SSAO activity by natural agents might reduce the potential adverse effects of creatine metabolism in population of T2DM." | 2.66 | Beneficial Impact of Semicarbazide-Sensitive Amine Oxidase Inhibition on the Potential Cytotoxicity of Creatine Supplementation in Type 2 Diabetes Mellitus. ( Deng, Y; Papukashvili, D; Rcheulishvili, N, 2020) |
| "The pathophysiology of obesity and type 2 diabetes as well as the necessity of preventive options based on the increasing prevalence of these two disorders worldwide is briefly discussed." | 2.53 | Coffee consumption, obesity and type 2 diabetes: a mini-review. ( Lima, DR; Santos, RM, 2016) |
| " Dose-response analysis suggested that incidence of T2DM decreased by 12 % [0." | 2.50 | Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies. ( Jiang, W; Jiang, X; Zhang, D, 2014) |
| "Coffee consumption was inversely associated with the risk of type 2 diabetes in a dose-response manner." | 2.50 | Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis. ( Bhupathiraju, SN; Chen, M; Ding, M; Hu, FB; van Dam, RM, 2014) |
| " The bioavailability and the distribution of each compound and its metabolites also contribute to coffee mechanisms of action." | 2.50 | Coffee components and cardiovascular risk: beneficial and detrimental effects. ( Buscemi, S; Galvano, F; Godos, J; Grosso, G; Li Volti, G; Marventano, S; Pluchinotta, FR, 2014) |
| "Caffeine intake has also been proposed to increase symptomatic warning signs of hypoglycemia in patients with type 1 diabetes and elevate blood glucose levels in patients with type 2 diabetes." | 2.49 | Caffeine and glucose homeostasis during rest and exercise in diabetes mellitus. ( Riddell, MC; Zaharieva, DP, 2013) |
| "Individuals with either type 2 diabetes (DM2) or pre-diabetes have microvascular dysfunction that contributes to morbidity and mortality." | 2.47 | Erythrocytes as controllers of perfusion distribution in the microvasculature of skeletal muscle. ( Achilleus, D; Bowles, EA; Ellsworth, ML; Sprague, RS, 2011) |
| "Caffeine has also been recently linked to weight loss and consequent reduction of the overall risks for developing the metabolic syndrome." | 2.46 | Caffeine (1, 3, 7-trimethylxanthine) in foods: a comprehensive review on consumption, functionality, safety, and regulatory matters. ( Gonzalez de Mejia, E; Heckman, MA; Weil, J, 2010) |
| "The prevention of type 2 diabetes has become a major public health objective." | 2.44 | [Does coffee protect against type 2 diabetes?]. ( Legrand, D; Scheen, AJ, 2007) |
| "The incidence of type 2 diabetes is reported to be lower in frequent coffee drinkers than in non-coffee drinkers." | 1.91 | Chlorogenic Acid and Caffeine in Coffee Restore Insulin Signaling in Pancreatic Beta Cells. ( Ando, M; Asahara, SI; Ihara, Y; Inoue, H; Kabutoya, H; Kido, Y; Kimura-Koyanagi, M; Seike, M, 2023) |
| "Pretreatment with caffeine to diabetic rats, resulted in improvement of structural changes and decrease in cytokine levels and immuno-markers, expression, and this was in a dose-dependent manner." | 1.91 | Caffeine protects against hippocampal alterations in type 2 diabetic rats via modulation of gliosis, inflammation and apoptosis. ( Al-Mahameed, AE; Fadel, R; Fatima, A; Jaradat, A; Nasr El-Din, WA; Othman, MA; Rashid, A; Tayem, Y, 2023) |
| "Obesity is an important risk factor for diabetes mellitus (DM) which is a major global health problem." | 1.72 | Effects of Isoprenaline on ventricular myocyte shortening and Ca ( Howarth, FC; Qureshi, MA; Sultan, A, 2022) |
| "Cilostazol (CSZ) has been shown to be a new treatment for cognitive impairment with limited efficacy." | 1.72 | Advancing combination treatment with cilostazol and caffeine for Alzheimer's disease in high fat-high fructose-STZ induced model of amnesia. ( Ahmed, AM; El-Mokhtar, MA; Farghaly, HSM; Gomaa, AA; Hemida, FK, 2022) |
| "Co-administration of PIO with caffeine enhances its antidiabetic effect, probably due to enhanced bioavailability of PIO, leading to clinical benefits in diabetic patients." | 1.62 | Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats: Impact on therapeutics. ( Alkahtani, SA; Alshabi, AM; Habeeb, MS; Shaikh, IA, 2021) |
| " The results showed that caffeine and ferulic acid, as well as green Robusta coffee, demonstrated the greatest inhibition of MAO-A activity, which may increase the bioavailability of serotonin." | 1.62 | Evaluation of the inhibition of monoamine oxidase A by bioactive coffee compounds protecting serotonin degradation. ( Budryn, G; Gałązka-Czarnecka, I; Grzelczyk, J; Oracz, J; Peña-García, J; Pérez-Sánchez, H; Szwajgier, D, 2021) |
| "A 74-year-old man who had type 2 diabetes mellitus of a duration of 20 years was admitted for syncope after eating a high carbohydrate meal." | 1.56 | Prevention of postprandial hypotension-related syncope by caffeine in a patient with long-standing diabetes mellitus. ( Furukawa, K; Hanyu, O; Iijima, K; Ishiguro, H; Ito, M; Morikawa, H; Sone, H; Sonoda, K; Suzuki, T, 2020) |
| "27)], and a dose-response relationship was observed for duration of drinking tea and the amount of tea consumed [P for trend <0." | 1.48 | Green tea consumption and risk of type 2 diabetes in Chinese adults: the Shanghai Women's Health Study and the Shanghai Men's Health Study. ( Cai, H; Gao, YT; Gerszten, RE; Ji, BT; Li, H; Liu, X; Shu, X; Shu, XO; Wang, T; Xiang, YB; Xu, W; Zheng, W, 2018) |
| "The liver phenotype, which is called nonalcoholic steatohepatitis (NASH), frequently progresses to hepatocellular carcinoma." | 1.46 | Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice. ( Baba, H; Morimoto, Y; Ogawa, H; Takahashi, T; Tsunematsu, T; Tsuneyama, K; Uehara, H; Watanabe, S, 2017) |
| "Next to male sex, type 2 diabetes status was the strongest predictor of caffeine intake." | 1.46 | A case-control field study on the relationships among type 2 diabetes, sleepiness and habitual caffeine intake. ( Berger, W; Holst, SC; Jetter, A; Landolt, HP; Langhans, W; Spinas, GA; Urry, E, 2017) |
| "As caffeine has been shown to be beneficial for diabetes, obesity and tau phosphorylation, we, therefore, used it as therapeutic treatment." | 1.46 | Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease. ( Calon, F; El Khoury, NB; Gratuze, M; Julien, C; Marcouiller, F; Marette, A; Morin, F; Planel, E; Turgeon, A; Whittington, RA, 2017) |
| "Non-alcoholic fatty liver disease (NAFLD) characterizes and predicts T2DM yet the relationship of coffee with this disorder remains unclear." | 1.42 | Associations of coffee consumption with markers of liver injury in the insulin resistance atherosclerosis study. ( Dickson, JC; Haffner, SM; Hamren, SJ; Hanley, AJ; Liese, AD; Lorenzo, C; Stiles, JK; Wagenknecht, LE; Watkins, SM, 2015) |
| "An alarming increase the prevalence of type 2 diabetes is forcing to constant analysis the lifestyle factors which can affect the risk of this illness." | 1.38 | [Coffee drinking and risk of type 2 diabetes mellitus. Optimistic scientific data]. ( Jarosz, M; Wierzejska, R, 2012) |
| "Black espresso coffee in people with type 2 diabetes mellitus results in a marginally greater excursion of glucose during a following OGTT compared with water or decaffeinated coffee." | 1.38 | A cross-over study of the acute effects of espresso coffee on glucose tolerance and insulin sensitivity in people with type 2 diabetes mellitus. ( Carroll, RW; Downie, M; Krebs, JD; Parry-Strong, A; Weatherall, M, 2012) |
| "During follow-up, 918 incident cases of type 2 diabetes were documented." | 1.35 | Coffee and tea consumption and risk of type 2 diabetes. ( Beulens, JW; Boer, JM; Grobbee, DE; Spijkerman, A; Uiterwaal, CS; van der A, DL; van der Schouw, YT; van Dieren, S, 2009) |
| "Metabolic syndrome was defined as the presence of > or = 3 of the following: waist circumference > or = 35 inches (women) or > or = 40 inches (men); fasting blood glucose > or = 100 mg/dL; serum triglycerides > or = 150 mg/dL; blood pressure > or = 135/85 mm Hg; and high-density lipoprotein cholesterol < 40 mg/dL (men) or < 50 mg/dL (women)." | 1.34 | Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. ( D'Agostino, RB; Dhingra, R; Fox, CS; Gaziano, JM; Jacques, PF; Meigs, JB; Sullivan, L; Vasan, RS; Wang, TJ, 2007) |
| " The diabetes risk was negatively related to the consumption in a dose-response manner." | 1.33 | Coffee, tea and diabetes: the role of weight loss and caffeine. ( Axen, KV; Boozer, CN; Greenberg, JA; Schnoll, R, 2005) |
| "In women with type 2 diabetes, higher caffeinated coffee consumption was associated with lower plasma concentrations of E-selectin (adjusted percentage change per 1 cup/d increment = -3." | 1.33 | Coffee consumption and markers of inflammation and endothelial dysfunction in healthy and diabetic women. ( Hu, FB; Lopez-Garcia, E; Qi, L; van Dam, RM, 2006) |
| "Caffeine has recently been used to test liver function, but the effect of diabetes on caffeine kinetics is not known." | 1.28 | Pharmacokinetics of caffeine in patients with decompensated type I and type II diabetes mellitus. ( Wietholtz, H; Zysset, T, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.76) | 18.7374 |
| 1990's | 6 (4.58) | 18.2507 |
| 2000's | 44 (33.59) | 29.6817 |
| 2010's | 57 (43.51) | 24.3611 |
| 2020's | 23 (17.56) | 2.80 |
| Authors | Studies |
|---|---|
| Srivastava, B | 1 |
| Sen, S | 1 |
| Bhakta, S | 1 |
| Sen, K | 1 |
| Yuan, S | 1 |
| Larsson, SC | 1 |
| Gomaa, AA | 1 |
| Farghaly, HSM | 1 |
| Ahmed, AM | 1 |
| El-Mokhtar, MA | 1 |
| Hemida, FK | 1 |
| Lijing, W | 1 |
| Sujie, K | 1 |
| Linxi, W | 1 |
| Lishan, H | 1 |
| Liqin, Q | 1 |
| Zhidong, Z | 1 |
| Kejun, W | 1 |
| Mengjun, Z | 1 |
| Xiaoying, L | 1 |
| Xiaohong, L | 1 |
| Libin, L | 1 |
| Sultan, A | 1 |
| Qureshi, MA | 1 |
| Howarth, FC | 1 |
| Chen, LW | 1 |
| Othman, MA | 1 |
| Fadel, R | 1 |
| Tayem, Y | 1 |
| Jaradat, A | 1 |
| Rashid, A | 1 |
| Fatima, A | 1 |
| Al-Mahameed, AE | 1 |
| Nasr El-Din, WA | 1 |
| Virgili, J | 1 |
| Motitis, P | 1 |
| Julal, G | 1 |
| Mavrommatis, Y | 1 |
| Pilic, L | 1 |
| Alcubierre, N | 1 |
| Granado-Casas, M | 1 |
| Bogdanov, P | 1 |
| Hernández, C | 1 |
| Ramos, H | 1 |
| Castelblanco, E | 1 |
| Real, J | 1 |
| Rubinat-Arnaldo, E | 1 |
| Traveset, A | 1 |
| Hernández, M | 1 |
| Jurjo, C | 1 |
| Vioque, J | 1 |
| Navarrete-Muñoz, EM | 1 |
| Simó, R | 1 |
| Mauricio, D | 1 |
| Ihara, Y | 1 |
| Asahara, SI | 1 |
| Inoue, H | 1 |
| Seike, M | 1 |
| Ando, M | 1 |
| Kabutoya, H | 1 |
| Kimura-Koyanagi, M | 1 |
| Kido, Y | 1 |
| Katsarova, SS | 1 |
| Redman, E | 1 |
| Arsenyadis, F | 1 |
| Brady, EM | 1 |
| Rowlands, AV | 1 |
| Edwardson, CL | 1 |
| Goff, LM | 1 |
| Khunti, K | 1 |
| Yates, T | 1 |
| Hall, AP | 1 |
| Davies, MJ | 1 |
| Henson, J | 1 |
| Cornelis, MC | 1 |
| Papukashvili, D | 2 |
| Rcheulishvili, N | 2 |
| Deng, Y | 2 |
| Pinaffi, ACDC | 1 |
| Sampaio, GR | 1 |
| Soares, MJ | 1 |
| Shahidi, F | 1 |
| de Camargo, AC | 1 |
| Torres, EAFS | 1 |
| Furukawa, K | 1 |
| Suzuki, T | 1 |
| Ishiguro, H | 1 |
| Morikawa, H | 1 |
| Sonoda, K | 1 |
| Iijima, K | 1 |
| Ito, M | 1 |
| Hanyu, O | 1 |
| Sone, H | 1 |
| van Dam, RM | 13 |
| Hu, FB | 12 |
| Willett, WC | 5 |
| Hang, D | 1 |
| Zeleznik, OA | 1 |
| He, X | 1 |
| Guasch-Ferre, M | 1 |
| Jiang, X | 3 |
| Li, J | 1 |
| Liang, L | 1 |
| Eliassen, AH | 1 |
| Clish, CB | 1 |
| Chan, AT | 1 |
| Hu, Z | 1 |
| Shen, H | 1 |
| Wilson, KM | 1 |
| Mucci, LA | 1 |
| Sun, Q | 2 |
| Giovannucci, EL | 2 |
| Song, M | 1 |
| Shao, XT | 1 |
| Cong, ZX | 1 |
| Liu, SY | 1 |
| Wang, Z | 1 |
| Zheng, XY | 1 |
| Wang, DG | 1 |
| Grzelczyk, J | 1 |
| Budryn, G | 1 |
| Peña-García, J | 1 |
| Szwajgier, D | 1 |
| Gałązka-Czarnecka, I | 1 |
| Oracz, J | 1 |
| Pérez-Sánchez, H | 1 |
| Alshabi, AM | 1 |
| Alkahtani, SA | 1 |
| Shaikh, IA | 1 |
| Habeeb, MS | 1 |
| Kolb, H | 2 |
| Martin, S | 2 |
| Kempf, K | 2 |
| Mansour, A | 1 |
| Mohajeri-Tehrani, MR | 1 |
| Samadi, M | 1 |
| Qorbani, M | 1 |
| Merat, S | 1 |
| Adibi, H | 1 |
| Poustchi, H | 1 |
| Hekmatdoost, A | 1 |
| Watanabe, S | 1 |
| Takahashi, T | 1 |
| Ogawa, H | 1 |
| Uehara, H | 1 |
| Tsunematsu, T | 1 |
| Baba, H | 1 |
| Morimoto, Y | 2 |
| Tsuneyama, K | 1 |
| Pihan-Le Bars, F | 1 |
| Gusto, G | 1 |
| Boutron-Ruault, MC | 2 |
| Fagherazzi, G | 2 |
| Bonnet, F | 1 |
| Nieber, K | 1 |
| Grosso, G | 2 |
| Godos, J | 2 |
| Galvano, F | 2 |
| Gökcen, BB | 1 |
| Şanlier, N | 1 |
| Kou, H | 1 |
| Wang, GH | 1 |
| Pei, LG | 1 |
| Zhang, L | 1 |
| Shi, C | 1 |
| Guo, Y | 1 |
| Wu, DF | 1 |
| Wang, H | 1 |
| Reis, CEG | 1 |
| Paiva, CLRDS | 1 |
| Amato, AA | 1 |
| Lofrano-Porto, A | 1 |
| Wassell, S | 1 |
| Bluck, LJC | 1 |
| Dórea, JG | 1 |
| da Costa, THM | 1 |
| James, JE | 1 |
| West, RK | 1 |
| Ravona-Springer, R | 1 |
| Livny, A | 1 |
| Heymann, A | 1 |
| Shahar, D | 1 |
| Leroith, D | 1 |
| Preiss, R | 1 |
| Zukran, R | 1 |
| Silverman, JM | 1 |
| Schnaider-Beeri, M | 1 |
| Liu, X | 2 |
| Xu, W | 1 |
| Cai, H | 1 |
| Gao, YT | 1 |
| Li, H | 1 |
| Ji, BT | 1 |
| Shu, X | 1 |
| Wang, T | 1 |
| Gerszten, RE | 1 |
| Zheng, W | 1 |
| Xiang, YB | 1 |
| Shu, XO | 1 |
| Mirmiran, P | 1 |
| Carlström, M | 1 |
| Bahadoran, Z | 1 |
| Azizi, F | 1 |
| Aghamohammadi, A | 1 |
| Akrami, SM | 1 |
| Yaghmaie, M | 1 |
| Rezaei, N | 1 |
| Azizi, G | 1 |
| Yaseri, M | 1 |
| Nosrati, H | 1 |
| Zaki-Dizaji, M | 1 |
| Gravel, S | 1 |
| Chiasson, JL | 1 |
| Turgeon, J | 1 |
| Grangeon, A | 1 |
| Michaud, V | 1 |
| Doo, T | 1 |
| Steinbrecher, A | 1 |
| Kolonel, LN | 1 |
| Maskarinec, G | 1 |
| Zaharieva, DP | 1 |
| Riddell, MC | 1 |
| Zhang, D | 1 |
| Jiang, W | 1 |
| Alkaabi, J | 1 |
| Al-Dabbagh, B | 1 |
| Saadi, H | 1 |
| Gariballa, S | 1 |
| Yasin, J | 1 |
| Ritchie, K | 1 |
| Ancelin, ML | 1 |
| Amieva, H | 1 |
| Rouaud, O | 1 |
| Carrière, I | 1 |
| Ding, M | 1 |
| Bhupathiraju, SN | 2 |
| Chen, M | 1 |
| Ludwig, IA | 1 |
| Clifford, MN | 1 |
| Lean, ME | 2 |
| Ashihara, H | 1 |
| Crozier, A | 1 |
| Chanson, P | 1 |
| Sun, T | 1 |
| Guo, J | 1 |
| Chen, H | 2 |
| Zhang, J | 1 |
| Zhang, X | 3 |
| Wang, F | 1 |
| Xu, Z | 1 |
| Huang, X | 1 |
| Sha, J | 1 |
| Chan, HC | 1 |
| Naidoo, P | 1 |
| Islam, MS | 1 |
| Pluchinotta, FR | 1 |
| Marventano, S | 1 |
| Buscemi, S | 1 |
| Li Volti, G | 1 |
| Palatini, P | 1 |
| Dickson, JC | 1 |
| Liese, AD | 1 |
| Lorenzo, C | 1 |
| Haffner, SM | 1 |
| Watkins, SM | 1 |
| Hamren, SJ | 1 |
| Stiles, JK | 1 |
| Wagenknecht, LE | 1 |
| Hanley, AJ | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Type 2 Diabetes on CYP450s Activities; Intersubject Variability in Drug Metabolism.[NCT02291666] | Phase 4 | 73 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| Does Combined Caffeine and Carbohydrate Ingestion Counter the Exercise-mediated Fall in Glycaemia in Individuals With Type 1 Diabetes on Insulin Degludec? The DE-CAF Study[NCT04671043] | 21 participants (Actual) | Interventional | 2022-02-04 | Completed | |||
| The Effect of Caffeine on the Narcoleptic Patients Randomized Controlled Clinical Trial[NCT02832336] | Phase 1/Phase 2 | 16 participants (Actual) | Interventional | 2016-10-01 | Completed | ||
| Effect of Date Fruit Phytoestrogen on the Glycemic Control of Patients With Type 2 Diabetes: A Randomized Clinical Trial.[NCT04616066] | 79 participants (Actual) | Interventional | 2021-10-10 | Completed | |||
| Effects of Caffeinated and Decaffeinated Coffee on Body Weight and Glucose Tolerance[NCT00305097] | 45 participants (Actual) | Interventional | 2006-05-31 | Completed | |||
| A Pilot, Randomized, Double-blind, Placebo-controlled, Parallel Design Study to Evaluate the Effectiveness and Safety of an Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health Among [NCT05170113] | 79 participants (Actual) | Interventional | 2021-11-02 | Completed | |||
| [NCT00005182] | 50,000 participants (Actual) | Observational | 1985-12-31 | Completed | |||
| Effect of Coffee and Tea Consumption on Adolescent Weight Control - a Randomized Clinical Trial[NCT05181176] | 63 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | |||
| Neuroplastic Alterations of the Motor Cortex by Caffeine: Differences Between Caffeine and Non-caffeine Users and Influence of Vigilance During Stimulation[NCT04011670] | 30 participants (Actual) | Interventional | 2019-07-15 | Completed | |||
| Cortical Excitability Changes on the Sensorimotor Cortex Induced by Caffeine Consumption: A TMS Study[NCT03720665] | 30 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
32 reviews available for caffeine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Adiposity, diabetes, lifestyle factors and risk of gastroesophageal reflux disease: a Mendelian randomization study.
Topics: Adiposity; Body Mass Index; Caffeine; Coffee; Diabetes Mellitus, Type 2; Gastroesophageal Reflux; Ge | 2022 |
The impact of genetic variability on the relationship between caffeine and cardiometabolic outcomes: A systematic review.
Topics: Adult; Caffeine; Cardiovascular Diseases; Cross-Sectional Studies; Cytochrome P-450 CYP1A2; Diabetes | 2023 |
Attenuation of Weight Gain and Prevention of Associated Pathologies by Inhibiting SSAO.
Topics: Adipocytes; Adolescent; Adult; Aged; Amine Oxidase (Copper-Containing); Animals; Anti-Obesity Agents | 2020 |
Beneficial Impact of Semicarbazide-Sensitive Amine Oxidase Inhibition on the Potential Cytotoxicity of Creatine Supplementation in Type 2 Diabetes Mellitus.
Topics: Adipokines; Amine Oxidase (Copper-Containing); Caffeine; Copper; Creatine; Diabetes Mellitus, Type 2 | 2020 |
Coffee, Caffeine, and Health.
Topics: Caffeine; Cardiovascular Diseases; Cholesterol; Coffee; Diabetes Mellitus, Type 2; Diterpenes; Human | 2020 |
Coffee and Lower Risk of Type 2 Diabetes: Arguments for a Causal Relationship.
Topics: Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Genome-Wide Association Study; Humans; I | 2021 |
The Impact of Coffee on Health.
Topics: Animals; Caffeine; Cardiovascular System; Coffee; Diabetes Mellitus, Type 2; Humans; Inflammatory Bo | 2017 |
Coffee, Caffeine, and Health Outcomes: An Umbrella Review.
Topics: Caffeine; Cardiovascular Diseases; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Male; Neoplasm | 2017 |
Coffee consumption and disease correlations.
Topics: Caffeine; Cardiovascular Diseases; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Diterpenes; | 2019 |
Are coffee's alleged health protective effects real or artifact? The enduring disjunction between relevant experimental and observational evidence.
Topics: Artifacts; Caffeine; Cardiovascular Diseases; Coffee; Diabetes Mellitus, Type 2; Humans; Hypertensio | 2018 |
Caffeine and glucose homeostasis during rest and exercise in diabetes mellitus.
Topics: Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Glucose; Homeostasis; Humans; Insulin | 2013 |
Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies.
Topics: Body Mass Index; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fema | 2014 |
Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Male; | 2014 |
Coffee: biochemistry and potential impact on health.
Topics: Alkaloids; Animals; Antioxidants; Caffeine; Cardiovascular Diseases; Chlorogenic Acid; Coffee; Diabe | 2014 |
Coffee components and cardiovascular risk: beneficial and detrimental effects.
Topics: Alkaloids; Caffeine; Cardiovascular Diseases; Cardiovascular System; Chlorogenic Acid; Coffee; Diabe | 2014 |
Coffee consumption, obesity and type 2 diabetes: a mini-review.
Topics: Animals; Blood Glucose; Caffeine; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Disease Model | 2016 |
Sugar and Type 2 diabetes.
Topics: Beverages; Caffeine; Diabetes Mellitus, Type 2; Diet; Dietary Sugars; Energy Intake; Health Surveys; | 2016 |
Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study.
Topics: Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Caffeine; Diabetes Mellitus, Type 2; Fatty Aci | 2016 |
Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: a systematic review and meta-analysis.
Topics: Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Ran | 2016 |
Coffee consumption and risk of type 2 diabetes, cardiovascular diseases, and cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Caffeine; Cardiovascular Diseases; Causality; Central Ne | 2008 |
Coffee, glucose homeostasis, and insulin resistance: physiological mechanisms and mediators.
Topics: Animals; Antioxidants; Blood Glucose; Caffeine; Central Nervous System Stimulants; Coffee; Diabetes | 2008 |
Caffeine, diabetes, cognition, and dementia.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Coffee; Cognition Disorders; Dementia; Diabete | 2010 |
[Clinical research on improvement of glucose metabolic marker level by coffee drinking-validity of saliva caffeine concentration measurement].
Topics: Caffeine; Chromatography, High Pressure Liquid; Coffee; Diabetes Mellitus, Type 2; Glucose; Glucose | 2010 |
Caffeine (1, 3, 7-trimethylxanthine) in foods: a comprehensive review on consumption, functionality, safety, and regulatory matters.
Topics: Animals; Beverages; Caffeine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Food Analysis; Hum | 2010 |
Erythrocytes as controllers of perfusion distribution in the microvasculature of skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Caffeine; Cilostazol; Diabetes Mellitus, Type 2; Erythrocytes; Huma | 2011 |
Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus.
Topics: Beverages; Blood Glucose; Caffeine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, | 2013 |
Effect of dietary factors on incidence of type 2 diabetes: a systematic review of cohort studies.
Topics: Blood Glucose; Caffeine; Cohort Studies; Diabetes Mellitus, Type 2; Diet; Diet Records; Dietary Fats | 2005 |
Coffee and type 2 diabetes: from beans to beta-cells.
Topics: Adult; Aged; Aged, 80 and over; Caffeine; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Femal | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee consumption and risk of type 2 diabetes and heart disease.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Genetic Predisposition to Dise | 2007 |
[Does coffee protect against type 2 diabetes?].
Topics: Antioxidants; Body Weight; Caffeine; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Dose-Respo | 2007 |
Insulin receptor- and nonreceptor-controlled cellular substrate processing. A review of clinical studies in the isolated human adipocyte model.
Topics: 3-O-Methylglucose; Adipose Tissue; Biological Transport; Blood Cells; Caffeine; Cells, Cultured; Dia | 1985 |
14 trials available for caffeine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Altered Caffeine Metabolism Is Associated With Recurrent Hypoglycemia in Type 2 Diabetes Mellitus: A UPLC-MS-Based Untargeted Metabolomics Study.
Topics: Biomarkers; Caffeine; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Li | 2022 |
Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-c
Topics: Caffeine; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Met | 2021 |
Decaffeinated coffee improves insulin sensitivity in healthy men.
Topics: Adult; Blood Glucose; Caffeine; Coffee; Cross-Over Studies; Diabetes Mellitus, Type 2; Glucose Toler | 2018 |
Caffeine intake enhances the benefits of sodium glucose transporter 2 inhibitor.
Topics: Biomarkers; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Diabetes Mellitus, Type | 2016 |
Delayed effects of coffee, tea and sucrose on postprandial glycemia in lean, young, healthy adults.
Topics: Adult; Area Under Curve; Beverages; Blood Glucose; Caffeine; Coffee; Cross-Over Studies; Diabetes Me | 2008 |
Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trial.
Topics: Adiponectin; Adult; Anti-Inflammatory Agents; Apolipoproteins; Biomarkers; Blood Glucose; Caffeic Ac | 2010 |
Coffee and caffeine consumption in relation to sex hormone-binding globulin and risk of type 2 diabetes in postmenopausal women.
Topics: Aged; Beverages; Caffeine; Coffee; Diabetes Mellitus, Type 2; Diet; Double-Blind Method; Feeding Beh | 2011 |
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial.
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Beverages; Blood Glucose; Caffeine; Coffee; Diabetes Me | 2011 |
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial.
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Beverages; Blood Glucose; Caffeine; Coffee; Diabetes Me | 2011 |
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial.
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Beverages; Blood Glucose; Caffeine; Coffee; Diabetes Me | 2011 |
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trial.
Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Beverages; Blood Glucose; Caffeine; Coffee; Diabetes Me | 2011 |
The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Body Mass Index; Boston; Caffeine; Coffee; Dehydroepiandrosterone Sulfate; | 2012 |
Caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetes.
Topics: Adult; Area Under Curve; Blood Glucose; Caffeine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Doub | 2004 |
Caffeine increases ambulatory glucose and postprandial responses in coffee drinkers with type 2 diabetes.
Topics: Aged; Blood Glucose; Caffeine; Coffee; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind M | 2008 |
Antipyrine, coumarin and glipizide affect n-acetylation measured by caffeine test.
Topics: Acetylation; Adult; Analysis of Variance; Antipyrine; Caffeine; Coumarins; Diabetes Mellitus, Type 2 | 1995 |
[Comparison of serum concentrations of caffeine, 4-methylaminoantipyrine, sulfamethazine and debrisoquin following oral administration of these substances as a cocktail in type II diabetics before and after insulin therapy].
Topics: Adult; Aged; Anti-Infective Agents; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 En | 1996 |
Evaluation of the influence of diabetes mellitus on antipyrine metabolism and CYP1A2 and CYP2D6 activity.
Topics: Acetylation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Antitussive Agents; Caffein | 2000 |
85 other studies available for caffeine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Effect of caffeine on the possible amelioration of diabetic neuropathy: A spectroscopic study.
Topics: Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Insulin; Insulin | 2022 |
Advancing combination treatment with cilostazol and caffeine for Alzheimer's disease in high fat-high fructose-STZ induced model of amnesia.
Topics: Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Caffeine; Cilostazol; Diabetes Mellitus, | 2022 |
Effects of Isoprenaline on ventricular myocyte shortening and Ca
Topics: Animals; Caffeine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Isoproterenol; Myocytes, Cardiac; O | 2022 |
Is it caffeine? Coffee consumption and future risk of type 2 diabetes among women with a history of gestational diabetes.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Pregnancy; Prosp | 2022 |
Caffeine protects against hippocampal alterations in type 2 diabetic rats via modulation of gliosis, inflammation and apoptosis.
Topics: Animals; Apoptosis; Caffeine; Caspase 3; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellit | 2023 |
Caffeine and the Risk of Diabetic Retinopathy in Type 2 Diabetes Mellitus: Findings from Clinical and Experimental Studies.
Topics: Animals; Caffeine; Coffee; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; | 2023 |
Chlorogenic Acid and Caffeine in Coffee Restore Insulin Signaling in Pancreatic Beta Cells.
Topics: Animals; Caffeine; Chlorogenic Acid; Diabetes Mellitus, Type 2; Insulin; Insulin Receptor Substrate | 2023 |
Differences in Dietary Intake, Eating Occasion Timings and Eating Windows between Chronotypes in Adults Living with Type 2 Diabetes Mellitus.
Topics: Adult; Caffeine; Chronotype; Diabetes Mellitus, Type 2; Eating; Humans; Sleep | 2023 |
Coffee and type 2 diabetes: time to consider alternative mechanisms?
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Risk Factors | 2020 |
Insoluble-Bound Polyphenols Released from Guarana Powder: Inhibition of Alpha-Glucosidase and Proanthocyanidin Profile.
Topics: alpha-Glucosidases; Brazil; Caffeine; Diabetes Mellitus, Type 2; Dietary Supplements; Glycoside Hydr | 2020 |
Prevention of postprandial hypotension-related syncope by caffeine in a patient with long-standing diabetes mellitus.
Topics: Aged; Autonomic Nervous System Diseases; Blood Pressure; Caffeine; Diabetes Mellitus, Type 2; Diabet | 2020 |
Metabolomic Signatures of Long-term Coffee Consumption and Risk of Type 2 Diabetes in Women.
Topics: Adult; Caffeine; Case-Control Studies; Coffee; Diabetes Mellitus, Type 2; Diet; Female; Humans; Hypo | 2020 |
Spatial analysis of metformin use compared with nicotine and caffeine consumption through wastewater-based epidemiology in China.
Topics: Caffeine; China; Cities; Diabetes Mellitus, Type 2; Humans; Metformin; Nicotiana; Nicotine; Spatial | 2021 |
Evaluation of the inhibition of monoamine oxidase A by bioactive coffee compounds protecting serotonin degradation.
Topics: Caffeine; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Monoamine Oxidase; Monoamine Oxidase | 2021 |
Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats: Impact on therapeutics.
Topics: Animals; Caffeine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Hypoglycemic | 2021 |
Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice.
Topics: Aging; Animals; Caffeine; Coffee; Diabetes Mellitus, Type 2; Hyperlipidemias; Insulin-Secreting Cell | 2017 |
Cross-sectional association of coffee and caffeine consumption with sex hormone-binding globulin in healthy nondiabetic women.
Topics: Caffeine; Coffee; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Healthy Volunteers; Hu | 2017 |
Effects of prenatal caffeine exposure on glucose homeostasis of adult offspring rats.
Topics: Animals; Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Female; Fetal Growth Retardation; Gene | 2017 |
Age Modulates the Association of Caffeine Intake With Cognition and With Gray Matter in Elderly Diabetics.
Topics: Aged; Caffeine; Cognition; Diabetes Mellitus, Type 2; Female; Gray Matter; Humans; Israel; Magnetic | 2019 |
Green tea consumption and risk of type 2 diabetes in Chinese adults: the Shanghai Women's Health Study and the Shanghai Men's Health Study.
Topics: Adult; Aged; Caffeine; Case-Control Studies; China; Diabetes Mellitus, Type 2; Female; Humans; Logis | 2018 |
Long-term effects of coffee and caffeine intake on the risk of pre-diabetes and type 2 diabetes: Findings from a population with low coffee consumption.
Topics: Adult; Aged; Caffeine; Central Nervous System Stimulants; Coffee; Diabetes Mellitus, Type 2; Female; | 2018 |
Individual Radiosensitivity Assessment of the Families of
Topics: Adolescent; Adult; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Atherosclerosis; C | 2018 |
Modulation of CYP450 Activities in Patients With Type 2 Diabetes.
Topics: Adult; Aged; Bupropion; Caffeine; Case-Control Studies; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cyto | 2019 |
Coffee intake and risk of type 2 diabetes: the Multiethnic Cohort.
Topics: Aged; Asian People; Caffeine; Coffea; Coffee; Diabetes Mellitus, Type 2; Feeding Behavior; Female; H | 2014 |
Effect of traditional Arabic coffee consumption on the glycemic index of Khalas dates tested in healthy and diabetic subjects.
Topics: Adult; Arecaceae; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dietary Carbohydrates; | 2013 |
Effect of traditional Arabic coffee consumption on the glycemic index of Khalas dates tested in healthy and diabetic subjects.
Topics: Adult; Arecaceae; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dietary Carbohydrates; | 2013 |
Effect of traditional Arabic coffee consumption on the glycemic index of Khalas dates tested in healthy and diabetic subjects.
Topics: Adult; Arecaceae; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dietary Carbohydrates; | 2013 |
Effect of traditional Arabic coffee consumption on the glycemic index of Khalas dates tested in healthy and diabetic subjects.
Topics: Adult; Arecaceae; Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Dietary Carbohydrates; | 2013 |
The association between caffeine and cognitive decline: examining alternative causal hypotheses.
Topics: Aged; Aged, 80 and over; Body Mass Index; Caffeine; Coffee; Cognition; Cognition Disorders; Cross-Se | 2014 |
[The more cups of coffee, caffeinated or decaffeinated, the greater risk of type 2 diabetes].
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Male | 2014 |
Maternal caffeine exposure impairs insulin secretion by pancreatic β-cells and increases the risk of type II diabetes mellitus in offspring.
Topics: Animals; Apoptosis; Birth Weight; Blood Glucose; Caffeine; Cells, Cultured; Diabetes Mellitus, Type | 2014 |
Development of an alternative non-obese non-genetic rat model of type 2 diabetes using caffeine and streptozotocin.
Topics: Animals; Blood Glucose; Body Weight; Caffeine; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 2014 |
Coffee consumption and risk of type 2 diabetes.
Topics: Adult; Beverages; Caffeine; Coffee; Cohort Studies; Cytochrome P-450 CYP1A2; Diabetes Mellitus, Type | 2015 |
Associations of coffee consumption with markers of liver injury in the insulin resistance atherosclerosis study.
Topics: Alanine Transaminase; alpha-2-HS-Glycoprotein; Aspartate Aminotransferases; Biomarkers; Caffeine; Co | 2015 |
Caffeine Impact on Metabolic Syndrome Components Is Modulated by a CYP1A2 Variant.
Topics: Aged; Alleles; Body Mass Index; Caffeine; Cholesterol, HDL; Cholesterol, LDL; Coffee; Cohort Studies | 2016 |
Malabsorption of L-T4 Due to Drip Coffee: A Case Report Using Predictors of Causation.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Drug Interactions; Fasting; Female; Hashimoto Disease; | 2016 |
A case-control field study on the relationships among type 2 diabetes, sleepiness and habitual caffeine intake.
Topics: Caffeine; Case-Control Studies; Circadian Rhythm; Coffee; Cytochrome P-450 CYP1A2; Diabetes Mellitus | 2017 |
Tau hyperphosphorylation in the brain of ob/ob mice is due to hypothermia: Importance of thermoregulation in linking diabetes and Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Body Temperature; Body Temperature Regulation; Caffeine; Central Nervous | 2017 |
Protective effect of caffeine on streptozotocin-induced beta-cell damage in rats.
Topics: Animals; Blood Glucose; Caffeine; Central Nervous System Stimulants; Diabetes Mellitus, Experimental | 2008 |
Coffee consumption and risk of cardiovascular diseases and all-cause mortality among men with type 2 diabetes.
Topics: Adult; Aged; Caffeine; Cardiovascular Diseases; Coffee; Cohort Studies; Diabetes Mellitus, Type 2; F | 2009 |
Coffee consumption and risk of cardiovascular events and all-cause mortality among women with type 2 diabetes.
Topics: Adult; Blood Pressure; Caffeine; Cardiovascular Diseases; Coffee; Cohort Studies; Diabetes Mellitus, | 2009 |
Relationship between long-term coffee consumption and components of the metabolic syndrome: the Amsterdam Growth and Health Longitudinal Study.
Topics: Caffeine; Cardiovascular Diseases; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Linear Models; | 2009 |
Coffee and tea consumption and risk of type 2 diabetes.
Topics: Adult; Aged; Blood Pressure; Body Mass Index; Caffeine; Chronic Disease; Coffee; Diabetes Mellitus, | 2009 |
[Side effects of caffeine].
Topics: Abortion, Spontaneous; Arteries; Caffeine; Cholesterol; Coronary Disease; Cytochrome P-450 CYP1A2; C | 2009 |
Differential effects of coffee on the risk of type 2 diabetes according to meal consumption in a French cohort of women: the E3N/EPIC cohort study.
Topics: Blood Glucose; Caffeine; Camellia sinensis; Cichorium intybus; Coffee; Diabetes Mellitus, Type 2; Di | 2010 |
Coffee components inhibit amyloid formation of human islet amyloid polypeptide in vitro: possible link between coffee consumption and diabetes mellitus.
Topics: Amino Acid Sequence; Amyloid; Caffeic Acids; Caffeine; Cell Line; Cell Survival; Chlorogenic Acid; C | 2011 |
Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice.
Topics: Animals; Beverages; Blood Glucose; Brain; Caffeine; Chlorogenic Acid; Coffee; Diabetes Mellitus, Typ | 2012 |
Coffee consumption and risk of chronic disease in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany study.
Topics: Adult; Aged; Caffeine; Cardiovascular Diseases; Coffee; Cohort Studies; Diabetes Mellitus, Type 2; F | 2012 |
Coffee intake and cardiovascular disease: virtue does not take center stage.
Topics: Adult; Animals; Beverages; Caffeine; Cardiovascular Diseases; Chlorogenic Acid; Cholesterol; Coffee; | 2012 |
A cross-over study of the acute effects of espresso coffee on glucose tolerance and insulin sensitivity in people with type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Caffeine; Central Nervous System Stimulants; Coffee; Cross-Over Studies; | 2012 |
Coffee and health. The latest buzz.
Topics: Alzheimer Disease; Blood Pressure; Bone and Bones; Caffeine; Central Nervous System Stimulants; Coff | 2012 |
Hypoglycemic effect of the water extract of Pu-erh tea.
Topics: Animals; Blood Glucose; Caffeine; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Fermentati | 2012 |
Effect of caffeine and capsaicin on the blood glucose levels of obese/diabetic KK-A(y) mice.
Topics: Animals; Blood Glucose; Caffeine; Capsaicin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ | 2012 |
[Coffee can protect against disease].
Topics: Alzheimer Disease; Anxiety; Caffeine; Cardiovascular Diseases; Coffee; Cognition; Diabetes Mellitus, | 2012 |
Caffeinated and caffeine-free beverages and risk of type 2 diabetes.
Topics: Adult; Aged; Beverages; Body Mass Index; Caffeine; Carbonated Beverages; Coffee; Diabetes Mellitus, | 2013 |
[Coffee drinking and risk of type 2 diabetes mellitus. Optimistic scientific data].
Topics: Adult; Caffeine; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Poland; Risk | 2012 |
Coffee consumption, serum γ-glutamyltransferase, and glucose tolerance status in middle-aged Japanese men.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; gamma-Glutamyltransferase; Glucose Intolerance; Humans; | 2013 |
Coffee consumption and risk of type 2 diabetes mellitus.
Topics: Adipose Tissue; Animals; Caffeine; Catecholamines; Diabetes Mellitus, Type 2; Energy Metabolism; Hum | 2003 |
Anti-obesity effects of a mixture of thiamin, arginine, caffeine, and citric acid in non-insulin dependent diabetic KK mice.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Arginine; Caffeine; Citric Acid; Diabetes Mellitus, Ty | 2003 |
Coffee consumption and risk for type 2 diabetes mellitus.
Topics: Adult; Age Factors; Aged; Body Mass Index; Caffeine; Coffee; Diabetes Mellitus, Type 2; Exercise; Fe | 2004 |
Summaries for patients. Coffee drinkers at lower risk for type 2 diabetes.
Topics: Adult; Aged; Body Mass Index; Caffeine; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Incidence | 2004 |
Caffeine impairs glucose metabolism in type 2 diabetes.
Topics: Beverages; Blood Glucose; Caffeine; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Meth | 2004 |
Coffee consumption and type 2 diabetes mellitus.
Topics: Caffeine; Coffee; Confounding Factors, Epidemiologic; Diabetes Mellitus, Type 2; Humans; Risk Factor | 2004 |
Coffee consumption and type 2 diabetes mellitus.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Prevalence; Risk Factors | 2004 |
Coffee consumption and type 2 diabetes mellitus.
Topics: Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Insulin; Risk Factors | 2004 |
Coffee consumption and type 2 diabetes mellitus.
Topics: Blood Glucose; Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Insulin; Risk Factors | 2004 |
Coffee consumption and type 2 diabetes mellitus.
Topics: Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Risk Factors; Selection Bias | 2004 |
Coffee: for most, it's safe. Coffee has been blamed for everything from moral turpitude to cancer. But none of the bad raps have stuck. Coffee may even be good for you.
Topics: Caffeine; Cardiovascular System; Coffee; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Li | 2004 |
Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Diabetes Mellitus, Type 2; Insulin Resista | 2004 |
Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training.
Topics: Adipose Tissue; Administration, Oral; Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Energy Int | 2005 |
Coffee, tea and diabetes: the role of weight loss and caffeine.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Caffeine; Coffee; Confidence Intervals; Diabetes Mellit | 2005 |
Coffee, caffeine, and risk of type 2 diabetes: a prospective cohort study in younger and middle-aged U.S. women.
Topics: Adult; Body Mass Index; Caffeine; Coffee; Cohort Studies; Diabetes Mellitus, Type 2; Dose-Response R | 2006 |
Summaries for patients. The relationship between green tea intake and type 2 diabetes in Japanese adults.
Topics: Adult; Age Factors; Aged; Beverages; Body Mass Index; Caffeine; Coffee; Cohort Studies; Diabetes Mel | 2006 |
The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults.
Topics: Adult; Age Factors; Aged; Beverages; Body Mass Index; Caffeine; Coffee; Cohort Studies; Diabetes Mel | 2006 |
Coffee consumption and markers of inflammation and endothelial dysfunction in healthy and diabetic women.
Topics: Adult; Aged; Biomarkers; C-Reactive Protein; Caffeine; Coffee; Cross-Sectional Studies; Diabetes Mel | 2006 |
Green tea, coffee, and diabetes.
Topics: Beverages; Caffeine; Coffee; Diabetes Mellitus, Type 2; Humans; Plant Extracts | 2006 |
Green tea, coffee, and diabetes.
Topics: Beverages; Body Mass Index; Caffeine; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Male; Sex C | 2006 |
Green tea, coffee, and diabetes.
Topics: Beverages; Caffeine; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Male; Risk Factors | 2006 |
Green tea, coffee, and diabetes.
Topics: Absorption; Beverages; Caffeine; Coffee; Diabetes Mellitus, Type 2; Female; Humans; Iron; Male | 2006 |
Does coffee consumption reduce the risk of type 2 diabetes in individuals with impaired glucose?
Topics: Aged; Caffeine; Central Nervous System Stimulants; Coffee; Diabetes Mellitus, Type 2; Drinking Behav | 2006 |
Long-term consumption of caffeine improves glucose homeostasis by enhancing insulinotropic action through islet insulin/insulin-like growth factor 1 signaling in diabetic rats.
Topics: Animals; Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Glucokinase; Glucose Clamp Technique; G | 2007 |
Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community.
Topics: Aged; Caffeine; Carbonated Beverages; Cholesterol, LDL; Cohort Studies; Cross-Sectional Studies; Dia | 2007 |
Coffee consumption is associated with higher plasma adiponectin concentrations in women with or without type 2 diabetes: a prospective cohort study.
Topics: Adiponectin; Aged; Body Mass Index; C-Reactive Protein; Caffeine; Coffee; Cohort Studies; Diabetes M | 2008 |
Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo.
Topics: Amides; Animals; Blood Glucose; Caffeine; Cells, Cultured; Diabetes Mellitus, Type 2; Enzyme Inhibit | 1998 |
Cardiac myofibrillar and sarcoplasmic reticulum function are not depressed in insulin-resistant JCR:LA-cp rats.
Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Cardiovascular Diseases; Diabetes Mellitus | 1999 |
[Coffee and diabetes--something to be really concerned about?].
Topics: Caffeine; Cardiovascular Diseases; Coffee; Diabetes Mellitus, Type 2; Feeding Behavior; Humans; Insu | 2002 |
Pharmacokinetics of caffeine in patients with decompensated type I and type II diabetes mellitus.
Topics: Adolescent; Adult; Aged; Caffeine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Mid | 1991 |
Unaltered drug metabolizing enzyme systems in type II diabetes mellitus before and during glyburide therapy.
Topics: Adult; Aminopyrine; Breath Tests; Caffeine; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type | 1990 |