Page last updated: 2024-10-24

caffeine and Compensatory Hyperinsulinemia

caffeine has been researched along with Compensatory Hyperinsulinemia in 8 studies

Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.

Research Excerpts

ExcerptRelevanceReference
"Caffeine decreased insulin sensitivity by 15% (P < 0."9.10Caffeine can decrease insulin sensitivity in humans. ( De Galan, BE; Keijzers, GB; Smits, P; Tack, CJ, 2002)
"Compounds other than macronutrients have been shown to influence blood glucose concentrations and insulin sensitivity in people with diabetes, with caffeine being one such substance."8.89Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013)
"Caffeine consumption is associated with a substantial reduction in insulin-mediated glucose uptake independent of obesity, type 2 diabetes, and chronic exercise."7.73Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training. ( Graham, TE; Hudson, R; Kilpatrick, K; Lee, S; Ross, R, 2005)
"Caffeine decreased insulin sensitivity by 15% (P < 0."5.10Caffeine can decrease insulin sensitivity in humans. ( De Galan, BE; Keijzers, GB; Smits, P; Tack, CJ, 2002)
"Compounds other than macronutrients have been shown to influence blood glucose concentrations and insulin sensitivity in people with diabetes, with caffeine being one such substance."4.89Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus. ( White, H; Whitehead, N, 2013)
"Caffeine consumption is associated with a substantial reduction in insulin-mediated glucose uptake independent of obesity, type 2 diabetes, and chronic exercise."3.73Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training. ( Graham, TE; Hudson, R; Kilpatrick, K; Lee, S; Ross, R, 2005)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Shearer, J1
Reimer, RA1
Hittel, DS1
Gault, MA1
Vogel, HJ1
Klein, MS1
Whitehead, N1
White, H1
Lee, S1
Hudson, R2
Kilpatrick, K1
Graham, TE2
Ross, R2
Battram, DS1
Dela, F1
Greer, F1
Graham, T1
Keijzers, GB1
De Galan, BE1
Tack, CJ1
Smits, P1
Rebolledo, A1
Milesi, V1
Raingo, J1
Gómez Alvis, A1
Rinaldi, GJ1
Grassi de Gende, AO1
Blecher, M1
Merlino, NS1
Ro'Ane, JT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Combined Caffeine and Carbohydrate Ingestion Counter the Exercise-mediated Fall in Glycaemia in Individuals With Type 1 Diabetes on Insulin Degludec? The DE-CAF Study[NCT04671043]21 participants (Actual)Interventional2022-02-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for caffeine and Compensatory Hyperinsulinemia

ArticleYear
Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2013, Volume: 26, Issue:2

    Topics: Beverages; Blood Glucose; Caffeine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes,

2013

Trials

4 trials available for caffeine and Compensatory Hyperinsulinemia

ArticleYear
Caffeine-Containing Energy Shots Cause Acute Impaired Glucoregulation in Adolescents.
    Nutrients, 2020, Dec-16, Volume: 12, Issue:12

    Topics: Acute Disease; Adolescent; Area Under Curve; Blood Glucose; Caffeine; Cross-Over Studies; Double-Bli

2020
Caffeine's impairment of insulin-mediated glucose disposal cannot be solely attributed to adrenaline in humans.
    The Journal of physiology, 2007, Sep-15, Volume: 583, Issue:Pt 3

    Topics: Adult; Blood Glucose; Blood Pressure; Caffeine; Central Nervous System Stimulants; Drug Interactions

2007
Caffeine ingestion decreases glucose disposal during a hyperinsulinemic-euglycemic clamp in sedentary humans.
    Diabetes, 2001, Volume: 50, Issue:10

    Topics: Administration, Oral; Adult; C-Peptide; Caffeine; Calorimetry; Double-Blind Method; Fatty Acids, Non

2001
Caffeine can decrease insulin sensitivity in humans.
    Diabetes care, 2002, Volume: 25, Issue:2

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Dipyridamole; Double-Blind Method; Epinephrine;

2002

Other Studies

3 other studies available for caffeine and Compensatory Hyperinsulinemia

ArticleYear
Caffeine ingestion is associated with reductions in glucose uptake independent of obesity and type 2 diabetes before and after exercise training.
    Diabetes care, 2005, Volume: 28, Issue:3

    Topics: Adipose Tissue; Administration, Oral; Blood Glucose; Caffeine; Diabetes Mellitus, Type 2; Energy Int

2005
Insulin preincubation effects on rat vessel contractile responses: role of the sarcoplasmic reticulum.
    Endothelium : journal of endothelial cell research, 2001, Volume: 8, Issue:4

    Topics: Animals; Aorta; Caffeine; Calcium; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Hyperinsu

2001
Controle of the metabolism and lipolytic effects of cyclic 3',5'-adenosine monophosphate in adipose tissue by insulin, methyl xanthines, and nicotinic acid.
    The Journal of biological chemistry, 1968, Jul-25, Volume: 243, Issue:14

    Topics: Adenine Nucleotides; Adipose Tissue; Animals; Blood Glucose; Caffeine; Cyclic AMP; Depression, Chemi

1968