caffeine has been researched along with Colorectal Cancer in 40 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Colorectal cancer (CRC) cells have been previously observed to be resistant to paclitaxel‑induced apoptosis by activation of the mitogen‑activated protein/extracellular signal‑regulated kinase (MEK)/ERK signaling pathway and increased expression of glucose‑regulated protein 78 (GRP78)." | 7.80 | Caffeine inhibits paclitaxel‑induced apoptosis in colorectal cancer cells through the upregulation of Mcl‑1 levels. ( Al-Azzam, SI; Alsaad, AA; Alzoubi, KH; Mhaidat, NM, 2014) |
| " Therefore, only -164A-->C (CYP1A2*1F) and -2464T-->delT (CYP1A2*1D) need to be analysed in the routine assessment of CYP1A2 genotype; (ii) in vivo CYP1A2 activity is lower in colorectal cancer patients than in controls, and (iii) CYP1A2 genotype had no effect on phenotype (based on the caffeine metabolite ratio)." | 7.72 | Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism. ( Barrett, JH; Bhambra, U; Boobis, AR; Garner, RC; Gooderham, NJ; Lightfoot, TJ; Sachse, C; Scollay, J; Smith, G; Wolf, CR, 2003) |
| " CYP2A6 phenotype was determined using caffeine as a probe drug in individuals participating in a case-control study of colorectal cancer (127 cases and 333 controls matched on age, gender, race, and geographic region)." | 7.71 | CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk. ( Hammons, G; Kadlubar, FF; Lang, NP; Nowell, S; Sweeney, C, 2002) |
| "The possible association of colorectal adenomatous polyps, a precursor lesion for colorectal cancer, with cigarette smoking, alcohol consumption, and coffee and caffeine consumption was investigated in a case-control study." | 7.68 | Cigarettes, alcohol, coffee, and caffeine as risk factors for colorectal adenomatous polyps. ( Fenoglio-Preiser, C; Forde, KA; Garbowski, GC; Lee, WC; Neugut, AI; Treat, MR; Waye, JD, 1993) |
| "Caffeine could enhance the effectiveness of an existing drug for CRC treatment despite having little impact on the cell survival rate of CRC cells." | 5.91 | Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer. ( Kim, KP; Lee, BK; Yoon, S, 2023) |
| "Colorectal cancer (CRC) cells have been previously observed to be resistant to paclitaxel‑induced apoptosis by activation of the mitogen‑activated protein/extracellular signal‑regulated kinase (MEK)/ERK signaling pathway and increased expression of glucose‑regulated protein 78 (GRP78)." | 3.80 | Caffeine inhibits paclitaxel‑induced apoptosis in colorectal cancer cells through the upregulation of Mcl‑1 levels. ( Al-Azzam, SI; Alsaad, AA; Alzoubi, KH; Mhaidat, NM, 2014) |
| "Coffee and tea contain numerous antimutagenic and antioxidant components and high levels of caffeine that may protect against colorectal cancer (CRC)." | 3.80 | Coffee and tea consumption, genotype-based CYP1A2 and NAT2 activity and colorectal cancer risk-results from the EPIC cohort study. ( Aleksandrova, K; Argüelles, M; Barricarte, A; Bech, BH; Boeing, H; Boutron-Ruault, MC; Braaten, T; Bueno-de-Mesquita, HB; Campa, D; Cauchi, S; Chirlaque, MD; Dik, VK; Dorronsoro, M; Engeset, D; Fagherazzi, G; Freisling, H; Froguel, P; Grioni, S; Gunter, MJ; Jenab, M; Jirström, K; Khaw, KT; Kühn, T; Licaj, I; Ljuslinder, I; Murphy, N; Nilsson, LM; Oikonomou, E; Olsen, A; Overvad, K; Palli, D; Panico, S; Peeters, PH; Peppa, E; Racine, A; Riboli, E; Romaguera-Bosch, D; Sánchez, MJ; Siersema, PD; Tjønneland, A; Travis, RC; Trichopoulou, A; Tumino, R; Uiterwaal, CS; Van Duijnhoven, FJ; Van Gils, CH; Van Oijen, MG; Vineis, P; Wallström, P; Wareham, N; Weiderpass, E; Yengo, L; Zamora-Ros, R, 2014) |
| " Parental HCT116 colorectal cancer cells that progress into mitosis following DNA damage, due to either G(2) checkpoint adaptation or G(2) checkpoint abrogation by caffeine or the Chk1 inhibitor UCN-01, delay in mitosis and show high rates of cytokinesis failure." | 3.76 | A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells. ( Kwak, S; Theurkauf, WE; Varmark, H, 2010) |
| " Therefore, only -164A-->C (CYP1A2*1F) and -2464T-->delT (CYP1A2*1D) need to be analysed in the routine assessment of CYP1A2 genotype; (ii) in vivo CYP1A2 activity is lower in colorectal cancer patients than in controls, and (iii) CYP1A2 genotype had no effect on phenotype (based on the caffeine metabolite ratio)." | 3.72 | Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism. ( Barrett, JH; Bhambra, U; Boobis, AR; Garner, RC; Gooderham, NJ; Lightfoot, TJ; Sachse, C; Scollay, J; Smith, G; Wolf, CR, 2003) |
| " CYP2A6 phenotype was determined using caffeine as a probe drug in individuals participating in a case-control study of colorectal cancer (127 cases and 333 controls matched on age, gender, race, and geographic region)." | 3.71 | CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk. ( Hammons, G; Kadlubar, FF; Lang, NP; Nowell, S; Sweeney, C, 2002) |
| "The possible association of colorectal adenomatous polyps, a precursor lesion for colorectal cancer, with cigarette smoking, alcohol consumption, and coffee and caffeine consumption was investigated in a case-control study." | 3.68 | Cigarettes, alcohol, coffee, and caffeine as risk factors for colorectal adenomatous polyps. ( Fenoglio-Preiser, C; Forde, KA; Garbowski, GC; Lee, WC; Neugut, AI; Treat, MR; Waye, JD, 1993) |
| "Postoperative ileus is a common condition following abdominal surgery." | 3.01 | Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial. ( Abu-Gazala, M; Bdolah-Abram, T; Gefen, R; Luques, L; Marom, G; Michael, S; Mintz, Y; Mizrahi, I; Parnasa, SY; Pikarsky, AJ; Rivkind, AI; Shussman, N, 2021) |
| "Caffeine could enhance the effectiveness of an existing drug for CRC treatment despite having little impact on the cell survival rate of CRC cells." | 1.91 | Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer. ( Kim, KP; Lee, BK; Yoon, S, 2023) |
| "A total of 1829 colorectal cancer cases were verified through June 2015." | 1.56 | Coffee consumption and risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort. ( Campbell, PT; Gapstur, SM; Guinter, MA; Jacobs, EJ; McCullough, ML; Um, CY, 2020) |
| "22,652 incident cancers occurred during 10." | 1.51 | Association between tea consumption and risk of cancer: a prospective cohort study of 0.5 million Chinese adults. ( Bian, Z; Chen, F; Chen, J; Chen, Y; Chen, Z; Guo, Y; Li, L; Li, X; Lv, J; Qiu, Z; Shen, Z; Wei, Y; Yang, L; Yu, C; Zhang, H, 2019) |
| "Colorectal and breast cancer cell lineages, HT-29 and MCF-7 cells, respectively, were exposed to different guaraná concentrations (0." | 1.46 | Guaraná, a Highly Caffeinated Food, Presents in vitro Antitumor Activity in Colorectal and Breast Cancer Cell Lines by Inhibiting AKT/mTOR/S6K and MAPKs Pathways. ( Assmann, CE; Azzolin, VF; Cadoná, FC; Cubillos-Rojas, M; da Cruz, IBM; Machado, AK; Ribeiro, EE; Rosa, JL; Sánchez-Tena, S; Schneider, T, 2017) |
| "Caffeine intake was not associated with cancer risk in a dose-response manner." | 1.42 | Coffee, tea, caffeine intake, and the risk of cancer in the PLCO cohort. ( Boffetta, P; Buys, SS; Galeone, C; Gren, L; Hashibe, M; La Vecchia, C; Zhang, ZF, 2015) |
| "Six hundred and eighty-one incident colorectal cancer cases were ascertained during a median follow-up of 11." | 1.39 | Prospective study of the relationship between coffee and tea with colorectal cancer risk: the PLCO Cancer Screening Trial. ( Ahn, J; Berndt, S; Dominianni, C; Hayes, RB; Huang, WY, 2013) |
| "The caffeine treatment suppressed the radiation-induced activation of ATM kinase, suppressed the activation of Chk2 kinase and inhibited the accumulation of cells in G2 phase." | 1.33 | Radiosensitization of tumor cells by modulation of ATM kinase. ( Choi, EK; Griffin, RJ; Ji, IM; Kim, JS; Kook, YH; Lee, DS; Lee, SR; Lim, BU; Park, HJ; Song, CW, 2006) |
| "Results were similar for colorectal cancer cases and controls." | 1.30 | Lifestyle and nutritional correlates of cytochrome CYP1A2 activity: inverse associations with plasma lutein and alpha-tocopherol. ( Cooney, RV; Custer, L; Franke, AA; Le Marchand, L; Wilkens, LR, 1997) |
| "Caffeine has also been shown to undergo 3-demethylation by CYP1A2, and it is further acetylated to 5-acetylamino-6-formylamino-3-methyluracil (AFMU) by the polymorphic NAT2." | 1.28 | Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. ( Butler, MA; Caporaso, NE; Hayes, RB; Kadlubar, FF; Lang, NP; Lawsen, MF; Massengill, JP; Teitel, CH; Vineis, P; Young, JF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (10.00) | 18.2507 |
| 2000's | 9 (22.50) | 29.6817 |
| 2010's | 15 (37.50) | 24.3611 |
| 2020's | 12 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nasseri, Y | 1 |
| Kasheri, E | 1 |
| Oka, K | 1 |
| Zhu, R | 1 |
| Smiley, A | 1 |
| Cohen, J | 1 |
| Ellenhorn, J | 1 |
| Barnajian, M | 1 |
| Yoon, S | 1 |
| Lee, BK | 1 |
| Kim, KP | 1 |
| Steiner, B | 1 |
| Ferrucci, LM | 1 |
| Mirabello, L | 1 |
| Lan, Q | 1 |
| Hu, W | 1 |
| Liao, LM | 1 |
| Savage, SA | 1 |
| De Vivo, I | 1 |
| Hayes, RB | 3 |
| Rajaraman, P | 1 |
| Huang, WY | 2 |
| Freedman, ND | 2 |
| Loftfield, E | 1 |
| Um, CY | 2 |
| McCullough, ML | 2 |
| Guinter, MA | 1 |
| Campbell, PT | 1 |
| Jacobs, EJ | 1 |
| Gapstur, SM | 2 |
| Mackintosh, C | 1 |
| Yuan, C | 2 |
| Ou, FS | 1 |
| Zhang, S | 1 |
| Niedzwiecki, D | 1 |
| Chang, IW | 1 |
| O'Neil, BH | 1 |
| Mullen, BC | 1 |
| Lenz, HJ | 1 |
| Blanke, CD | 1 |
| Venook, AP | 1 |
| Mayer, RJ | 1 |
| Fuchs, CS | 3 |
| Innocenti, F | 1 |
| Nixon, AB | 1 |
| Goldberg, RM | 1 |
| O'Reilly, EM | 1 |
| Meyerhardt, JA | 2 |
| Ng, K | 1 |
| Chapelle, N | 1 |
| Martel, M | 1 |
| Toes-Zoutendijk, E | 1 |
| Barkun, AN | 1 |
| Bardou, M | 1 |
| Kawada, T | 1 |
| Shojaei-Zarghani, S | 1 |
| Yari Khosroushahi, A | 1 |
| Rafraf, M | 1 |
| Asghari-Jafarabadi, M | 1 |
| Azami-Aghdash, S | 1 |
| Parnasa, SY | 2 |
| Marom, G | 1 |
| Bdolah-Abram, T | 1 |
| Gefen, R | 1 |
| Luques, L | 1 |
| Michael, S | 1 |
| Mizrahi, I | 1 |
| Abu-Gazala, M | 1 |
| Rivkind, AI | 1 |
| Mintz, Y | 1 |
| Pikarsky, AJ | 1 |
| Shussman, N | 2 |
| Korolkiewicz, PK | 1 |
| Cadoná, FC | 1 |
| Rosa, JL | 1 |
| Schneider, T | 1 |
| Cubillos-Rojas, M | 1 |
| Sánchez-Tena, S | 1 |
| Azzolin, VF | 1 |
| Assmann, CE | 1 |
| Machado, AK | 1 |
| Ribeiro, EE | 1 |
| da Cruz, IBM | 1 |
| Long, Y | 1 |
| Sanchez-Espiridion, B | 1 |
| Lin, M | 1 |
| White, L | 1 |
| Mishra, L | 1 |
| Raju, GS | 1 |
| Kopetz, S | 1 |
| Eng, C | 1 |
| Hildebrandt, MAT | 1 |
| Chang, DW | 1 |
| Ye, Y | 1 |
| Liang, D | 1 |
| Wu, X | 1 |
| Hu, Y | 1 |
| Ding, M | 1 |
| Wu, K | 1 |
| Smith-Warner, SA | 1 |
| Hu, FB | 1 |
| Chan, AT | 1 |
| Ogino, S | 1 |
| Giovannucci, EL | 1 |
| Song, M | 1 |
| Soares, PV | 1 |
| Kannen, V | 1 |
| Jordão Junior, AA | 1 |
| Garcia, SB | 1 |
| Li, X | 1 |
| Yu, C | 1 |
| Guo, Y | 1 |
| Bian, Z | 1 |
| Shen, Z | 1 |
| Yang, L | 1 |
| Chen, Y | 1 |
| Wei, Y | 1 |
| Zhang, H | 1 |
| Qiu, Z | 1 |
| Chen, J | 1 |
| Chen, F | 1 |
| Chen, Z | 1 |
| Lv, J | 1 |
| Li, L | 1 |
| Dominianni, C | 1 |
| Berndt, S | 1 |
| Ahn, J | 1 |
| Mhaidat, NM | 1 |
| Alzoubi, KH | 1 |
| Al-Azzam, SI | 1 |
| Alsaad, AA | 1 |
| Dik, VK | 1 |
| Bueno-de-Mesquita, HB | 1 |
| Van Oijen, MG | 1 |
| Siersema, PD | 1 |
| Uiterwaal, CS | 1 |
| Van Gils, CH | 1 |
| Van Duijnhoven, FJ | 1 |
| Cauchi, S | 1 |
| Yengo, L | 1 |
| Froguel, P | 1 |
| Overvad, K | 1 |
| Bech, BH | 1 |
| Tjønneland, A | 1 |
| Olsen, A | 1 |
| Boutron-Ruault, MC | 1 |
| Racine, A | 1 |
| Fagherazzi, G | 1 |
| Kühn, T | 1 |
| Campa, D | 1 |
| Boeing, H | 1 |
| Aleksandrova, K | 1 |
| Trichopoulou, A | 1 |
| Peppa, E | 1 |
| Oikonomou, E | 1 |
| Palli, D | 1 |
| Grioni, S | 1 |
| Vineis, P | 2 |
| Tumino, R | 1 |
| Panico, S | 1 |
| Peeters, PH | 1 |
| Weiderpass, E | 1 |
| Engeset, D | 1 |
| Braaten, T | 1 |
| Dorronsoro, M | 1 |
| Chirlaque, MD | 1 |
| Sánchez, MJ | 1 |
| Barricarte, A | 1 |
| Zamora-Ros, R | 1 |
| Argüelles, M | 1 |
| Jirström, K | 1 |
| Wallström, P | 1 |
| Nilsson, LM | 1 |
| Ljuslinder, I | 1 |
| Travis, RC | 1 |
| Khaw, KT | 1 |
| Wareham, N | 1 |
| Freisling, H | 1 |
| Licaj, I | 1 |
| Jenab, M | 1 |
| Gunter, MJ | 2 |
| Murphy, N | 1 |
| Romaguera-Bosch, D | 1 |
| Riboli, E | 1 |
| Tayyem, RF | 1 |
| Bawadi, HA | 1 |
| Shehadah, IN | 1 |
| Abu-Mweis, SS | 1 |
| Agraib, LM | 1 |
| Bani-Hani, KE | 1 |
| Al-Jaberi, T | 1 |
| Al-Nusairr, M | 1 |
| Heath, DD | 1 |
| Hashibe, M | 1 |
| Galeone, C | 1 |
| Buys, SS | 1 |
| Gren, L | 1 |
| Boffetta, P | 1 |
| Zhang, ZF | 1 |
| La Vecchia, C | 2 |
| Printz, C | 1 |
| Varmark, H | 1 |
| Kwak, S | 1 |
| Theurkauf, WE | 1 |
| Thomson, CA | 1 |
| Martínez, ME | 1 |
| Lu, JJ | 1 |
| Cai, YJ | 1 |
| Ding, J | 1 |
| Sinha, R | 1 |
| Cross, AJ | 1 |
| Daniel, CR | 1 |
| Graubard, BI | 1 |
| Wu, JW | 1 |
| Hollenbeck, AR | 1 |
| Park, Y | 1 |
| Sweeney, C | 2 |
| Coles, BF | 1 |
| Nowell, S | 2 |
| Lang, NP | 3 |
| Kadlubar, FF | 3 |
| Sachse, C | 1 |
| Bhambra, U | 1 |
| Smith, G | 1 |
| Lightfoot, TJ | 1 |
| Barrett, JH | 1 |
| Scollay, J | 1 |
| Garner, RC | 1 |
| Boobis, AR | 1 |
| Wolf, CR | 1 |
| Gooderham, NJ | 1 |
| Saito, Y | 1 |
| Gopalan, B | 1 |
| Mhashilkar, AM | 1 |
| Roth, JA | 1 |
| Chada, S | 1 |
| Zumstein, L | 1 |
| Ramesh, R | 1 |
| Yan, T | 1 |
| Desai, AB | 1 |
| Jacobberger, JW | 1 |
| Sramkoski, RM | 1 |
| Loh, T | 1 |
| Kinsella, TJ | 1 |
| Tavani, A | 1 |
| Michels, KB | 1 |
| Willett, WC | 1 |
| Giovannucci, E | 1 |
| Higdon, JV | 1 |
| Frei, B | 1 |
| Choi, EK | 1 |
| Ji, IM | 1 |
| Lee, SR | 1 |
| Kook, YH | 1 |
| Griffin, RJ | 1 |
| Lim, BU | 1 |
| Kim, JS | 1 |
| Lee, DS | 1 |
| Song, CW | 1 |
| Park, HJ | 1 |
| Lee, WC | 1 |
| Neugut, AI | 1 |
| Garbowski, GC | 1 |
| Forde, KA | 1 |
| Treat, MR | 1 |
| Waye, JD | 1 |
| Fenoglio-Preiser, C | 1 |
| Le Marchand, L | 1 |
| Franke, AA | 1 |
| Custer, L | 1 |
| Wilkens, LR | 1 |
| Cooney, RV | 1 |
| Cipriani, F | 1 |
| Geddes, M | 1 |
| Hammons, G | 1 |
| Butler, MA | 1 |
| Young, JF | 1 |
| Caporaso, NE | 1 |
| Teitel, CH | 1 |
| Massengill, JP | 1 |
| Lawsen, MF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Caffeine Enhance Bowel Recovery After Colorectal Surgery?[NCT03097900] | Phase 2 | 70 participants (Actual) | Interventional | 2017-11-02 | Completed | ||
| NCI-AARP Diet and Health Study[NCT00340015] | 566,401 participants (Actual) | Observational | 1995-10-24 | Completed | |||
| Neuroplastic Alterations of the Motor Cortex by Caffeine: Differences Between Caffeine and Non-caffeine Users and Influence of Vigilance During Stimulation[NCT04011670] | 30 participants (Actual) | Interventional | 2019-07-15 | Completed | |||
| Effect of Coffee and Tea Consumption on Adolescent Weight Control - a Randomized Clinical Trial[NCT05181176] | 63 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | |||
| Cortical Excitability Changes on the Sensorimotor Cortex Induced by Caffeine Consumption: A TMS Study[NCT03720665] | 30 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for caffeine and Colorectal Cancer
| Article | Year |
|---|---|
Recent advances in clinical practice: colorectal cancer chemoprevention in the average-risk population.
Topics: Alcohol Drinking; Allium; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Caffeine; | 2020 |
Dietary natural methylxanthines and colorectal cancer: a systematic review and meta-analysis.
Topics: Animals; Antineoplastic Agents; Caffeine; Colonic Neoplasms; Colorectal Neoplasms; Databases, Factua | 2020 |
Coffee, decaffeinated coffee, tea and cancer of the colon and rectum: a review of epidemiological studies, 1990-2003.
Topics: Antioxidants; Caffeine; Case-Control Studies; Central Nervous System Stimulants; Coffee; Cohort Stud | 2004 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
[Etiological epidemiology of colorectal tumors].
Topics: Alcohol Drinking; Caffeine; Cohort Studies; Colorectal Neoplasms; Diet; Disease Susceptibility; Etha | 1996 |
3 trials available for caffeine and Colorectal Cancer
| Article | Year |
|---|---|
Does coffee affect bowel recovery following minimally invasive colorectal operations? A three-armed randomized controlled trial.
Topics: Caffeine; Coffee; Colectomy; Colorectal Neoplasms; Humans; Ileus; Postoperative Complications; Time | 2023 |
Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial.
Topics: Adult; Aged; Caffeine; Colorectal Neoplasms; Gastrointestinal Motility; Humans; Ileus; Length of Sta | 2021 |
Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer.
Topics: Aryl Hydrocarbon Hydroxylases; Bacterial Proteins; Biomarkers; Caffeine; Carcinogens; Carrier Protei | 2002 |
32 other studies available for caffeine and Colorectal Cancer
| Article | Year |
|---|---|
Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer.
Topics: Adenocarcinoma; Caffeine; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; D | 2023 |
Association between coffee drinking and telomere length in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Topics: Aged; Caffeine; Coffee; Colorectal Neoplasms; Cross-Sectional Studies; Female; Humans; Lung Neoplasm | 2020 |
Coffee consumption and risk of colorectal cancer in the Cancer Prevention Study-II Nutrition Cohort.
Topics: Aged; Caffeine; Coffee; Colorectal Neoplasms; Female; Humans; Male; Prognosis; Prospective Studies; | 2020 |
Association of Coffee Intake With Survival in Patients With Advanced or Metastatic Colorectal Cancer.
Topics: Caffeine; Coffee; Colorectal Neoplasms; Humans; Male; Middle Aged; Proportional Hazards Models; Pros | 2020 |
Caffeinated and decaffeinated coffee intake and colorectal cancer: A risk assessment.
Topics: Caffeine; Coffee; Cohort Studies; Colorectal Neoplasms; Humans; Risk Assessment | 2020 |
Response to letter to the editor: Caffeinated and decaffeinated coffee intake and colorectal cancer: A risk assessment.
Topics: Caffeine; Coffee; Cohort Studies; Colorectal Neoplasms; Humans; Risk Assessment | 2020 |
Commentary on: "Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial" Tech Coloproctol. 2021 Apr 26. doi: 10.1007/s10151-021-02450-7.
Topics: Caffeine; Colon, Sigmoid; Colorectal Neoplasms; Elective Surgical Procedures; Humans; Prospective St | 2021 |
Caffeine and bowel recovery after elective colorectal resection: author's reply.
Topics: Caffeine; Colon, Sigmoid; Colorectal Neoplasms; Elective Surgical Procedures; Humans; Preoperative C | 2021 |
Guaraná, a Highly Caffeinated Food, Presents in vitro Antitumor Activity in Colorectal and Breast Cancer Cell Lines by Inhibiting AKT/mTOR/S6K and MAPKs Pathways.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caffeine; Cell Line, Tumor; Colorectal Neoplasm | 2017 |
Global and targeted serum metabolic profiling of colorectal cancer progression.
Topics: Adenoma; Adult; Aged; Caffeine; Case-Control Studies; Chromatography, Liquid; Colonic Polyps; Colore | 2017 |
Association Between Coffee Intake After Diagnosis of Colorectal Cancer and Reduced Mortality.
Topics: Adult; Aged; Caffeine; Central Nervous System Stimulants; Coffee; Colorectal Neoplasms; Female; Huma | 2018 |
Coffee, but Neither Decaffeinated Coffee nor Caffeine, Elicits Chemoprotection Against a Direct Carcinogen in the Colon of Wistar Rats.
Topics: alpha-Tocopherol; Animals; Anticarcinogenic Agents; Caffeine; Carcinogens; Coffee; Colon; Colorectal | 2019 |
Association between tea consumption and risk of cancer: a prospective cohort study of 0.5 million Chinese adults.
Topics: Adult; Aged; Alcohol Drinking; Asian People; Breast Neoplasms; Caffeine; China; Colorectal Neoplasms | 2019 |
Prospective study of the relationship between coffee and tea with colorectal cancer risk: the PLCO Cancer Screening Trial.
Topics: Caffeine; Coffee; Colorectal Neoplasms; Feeding Behavior; Female; Humans; Male; Middle Aged; Prospec | 2013 |
Caffeine inhibits paclitaxel‑induced apoptosis in colorectal cancer cells through the upregulation of Mcl‑1 levels.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Butadienes; Caffeine; Cell Line, Tumor; Cell Survival; | 2014 |
Coffee and tea consumption, genotype-based CYP1A2 and NAT2 activity and colorectal cancer risk-results from the EPIC cohort study.
Topics: Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Case-Control Studies; Coffee; Cohort Studies; | 2014 |
Macro- and micronutrients consumption and the risk for colorectal cancer among Jordanians.
Topics: Adult; Aged; Anticarcinogenic Agents; Caffeine; Colorectal Neoplasms; Diet; Diet Surveys; Energy Int | 2015 |
Coffee, tea, caffeine intake, and the risk of cancer in the PLCO cohort.
Topics: Aged; Caffeine; Coffee; Colorectal Neoplasms; Female; Humans; Lung Neoplasms; Male; Middle Aged; Ova | 2015 |
Regular coffee consumption may improve survival in patients with colon cancer.
Topics: Caffeine; Coffee; Colorectal Neoplasms; Humans; Neoplasm Recurrence, Local; Prognosis; Survival Anal | 2015 |
A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells.
Topics: Animals; Caffeine; Checkpoint Kinase 1; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Breaks, Doubl | 2010 |
Coffee, tea, what beverage for me? Associations between beverage intake and colorectal neoplasia risk.
Topics: Caffeine; Carbonated Beverages; Coffee; Colorectal Neoplasms; Confounding Factors, Epidemiologic; Fe | 2010 |
Curcumin induces DNA damage and caffeine-insensitive cell cycle arrest in colorectal carcinoma HCT116 cells.
Topics: Antineoplastic Agents; Caffeine; Colorectal Neoplasms; Curcumin; DNA Damage; G2 Phase; HCT116 Cells; | 2011 |
Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective study.
Topics: Beverages; Caffeine; Coffee; Colorectal Neoplasms; Diet; Feeding Behavior; Female; Follow-Up Studies | 2012 |
Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism.
Topics: Aged; Aged, 80 and over; Caffeine; Colorectal Neoplasms; Cytochrome P-450 CYP1A2; Gene Frequency; Hu | 2003 |
Adenovirus-mediated PTEN treatment combined with caffeine produces a synergistic therapeutic effect in colorectal cancer cells.
Topics: Adenoviridae; Apoptosis; Caffeine; Cell Division; Colon; Colorectal Neoplasms; Drug Synergism; Fibro | 2003 |
CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
Topics: Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Base Pair Mismatch; Caffein | 2004 |
Coffee, tea, and caffeine consumption and incidence of colon and rectal cancer.
Topics: Adult; Aged; Caffeine; Coffee; Cohort Studies; Colorectal Neoplasms; Feeding Behavior; Female; Human | 2005 |
Radiosensitization of tumor cells by modulation of ATM kinase.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle; Cell Cycle Proteins; Cell L | 2006 |
Cigarettes, alcohol, coffee, and caffeine as risk factors for colorectal adenomatous polyps.
Topics: Adenomatous Polyps; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Caffeine; Case-Control Studies | 1993 |
Lifestyle and nutritional correlates of cytochrome CYP1A2 activity: inverse associations with plasma lutein and alpha-tocopherol.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Caffeine; Case-Control Studies; Coffee; Colorectal Neop | 1997 |
CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk.
Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Biomarkers; Caffeine; Case-Control Studies; Central Nerv | 2002 |
Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.
Topics: Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; China; Colorectal Neoplasms; Cytochrome P-450 | 1992 |