caffeine has been researched along with Colonic Neoplasms in 30 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thus, it was assessed whether caffeine (CAF) and/or chlorogenic acid (CGA) attenuates the early-stage of chemically induced mouse colon carcinogenesis." | 8.12 | Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p. ( Barbisan, LF; Bartolomeu, AR; Besharat, ZM; Chaves, MÁG; Corrales, JAM; Lisón, CG; Romualdo, GR, 2022) |
| "Caffeine could enhance the effectiveness of an existing drug for CRC treatment despite having little impact on the cell survival rate of CRC cells." | 5.91 | Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer. ( Kim, KP; Lee, BK; Yoon, S, 2023) |
| " Thus, it was assessed whether caffeine (CAF) and/or chlorogenic acid (CGA) attenuates the early-stage of chemically induced mouse colon carcinogenesis." | 4.12 | Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p. ( Barbisan, LF; Bartolomeu, AR; Besharat, ZM; Chaves, MÁG; Corrales, JAM; Lisón, CG; Romualdo, GR, 2022) |
| "Thirty-four Balb/c mice were randomly assigned to five groups, including the control, CAC control, CAC + caffeine, colitis control and colitis + caffeine." | 3.80 | Increased expression and possible role of chitinase 3-like-1 in a colitis-associated carcinoma model. ( Huang, K; Li, C; Li, RH; Ma, JY; Tan, G; Zhi, FC, 2014) |
| " The body weight, weight gain, food consumption, aberrant foci crypt, mucin depleted foci, stress biomarkers protein carbonyl and malondialdehyde, biochemical parameters and behavior of the rats were compared between the experimental and control groups within a framework of colon carcinogenesis." | 3.77 | Organic and conventional Coffea arabica L.: a comparative study of the chemical composition and physiological, biochemical and toxicological effects in Wistar rats. ( Azevedo, L; Brigagão, MR; Carvalho, Ddo C; de Paula, FB; dos Santos, MH; Giusti-Paiva, A, 2011) |
| "The effect of coffee on colon cancer recurrence and survival is unknown." | 2.80 | Coffee Intake, Recurrence, and Mortality in Stage III Colon Cancer: Results From CALGB 89803 (Alliance). ( Atienza, D; Benson, A; Fuchs, CS; Giovannucci, EL; Guercio, BJ; Hantel, A; Hu, FB; Kindler, H; Mayer, RJ; Messino, M; Meyerhardt, JA; Mowat, RB; Niedzwiecki, D; Ogino, S; Saltz, LB; Sato, K; Venook, A; Whittom, R; Willett, WC; Wu, K; Ye, X, 2015) |
| "Caffeine is a widely consumed stimulant, known for its positive effects on physical and mental performance." | 1.91 | Caffeine-Supplemented Diet Prevents Fatigue-Like Behavior in Tumor-Bearing Mice. ( Ferdaos, N; Harada, A; Horaguchi, T; Kasai, S; Masuda, E; Yoshizawa, K, 2023) |
| "Caffeine could enhance the effectiveness of an existing drug for CRC treatment despite having little impact on the cell survival rate of CRC cells." | 1.91 | Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer. ( Kim, KP; Lee, BK; Yoon, S, 2023) |
| " To distinguish between blocking and suppressing effects, and thus provide mechanistic insights into prevention during the initiation versus post-initiation phases of carcinogenesis, white tea, and green tea were administered at 2% (w/v) as the sole source of drinking fluid either 2 wk before and 2 wk during PhIP dosing (100 mg/kg, every other day by oral gavage), or starting 1 wk after the carcinogen and continued until the study was terminated at 16 wk." | 1.34 | Comparison of white tea, green tea, epigallocatechin-3-gallate, and caffeine as inhibitors of PhIP-induced colonic aberrant crypts. ( Bailey, GS; Carter, O; Dashwood, RH; Dashwood, WM; Fischer, KA; Löhr, CV; Orner, GA; Pereira, CB; Wang, R; Williams, DE, 2007) |
| "The tumor lines were hepatocellular carcinoma and colon adenocarcinoma." | 1.29 | Differential radiosensitization of radioresistant human cancer cells by caffeine. ( Boonkitticharoen, V; Laohathai, K; Puribhat, S, 1993) |
| "Risk for colon cancer associated with alcohol use was greatly attenuated after adjusting for caffeine and pipe use in males; males who consumed higher levels of caffeine during the two to three years prior to the interview were at higher risk than males who consumed low levels of caffeine (OR = 2." | 1.28 | Tobacco, alcohol, coffee, and caffeine as risk factors for colon cancer in a low-risk population. ( Ford, MH; French, TK; Robison, LM; Schuman, KL; Slattery, ML; Sorenson, AW; West, DW, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.67) | 18.7374 |
| 1990's | 8 (26.67) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 6 (20.00) | 24.3611 |
| 2020's | 5 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bartolomeu, AR | 1 |
| Romualdo, GR | 1 |
| Lisón, CG | 1 |
| Besharat, ZM | 1 |
| Corrales, JAM | 1 |
| Chaves, MÁG | 1 |
| Barbisan, LF | 1 |
| Ferdaos, N | 1 |
| Harada, A | 1 |
| Masuda, E | 1 |
| Kasai, S | 1 |
| Horaguchi, T | 1 |
| Yoshizawa, K | 1 |
| Emile, SH | 1 |
| Barsom, SH | 1 |
| Garoufalia, Z | 1 |
| Wexner, SD | 1 |
| Yoon, S | 1 |
| Lee, BK | 1 |
| Kim, KP | 1 |
| Shojaei-Zarghani, S | 1 |
| Yari Khosroushahi, A | 1 |
| Rafraf, M | 1 |
| Asghari-Jafarabadi, M | 1 |
| Azami-Aghdash, S | 1 |
| Acar, E | 1 |
| Gürdeniz, G | 1 |
| Savorani, F | 1 |
| Hansen, L | 1 |
| Olsen, A | 1 |
| Tjønneland, A | 1 |
| Dragsted, LO | 1 |
| Bro, R | 1 |
| Strzeszewska, A | 1 |
| Alster, O | 1 |
| Mosieniak, G | 1 |
| Ciolko, A | 1 |
| Sikora, E | 1 |
| Ma, JY | 1 |
| Li, RH | 1 |
| Huang, K | 1 |
| Tan, G | 1 |
| Li, C | 1 |
| Zhi, FC | 1 |
| Guercio, BJ | 1 |
| Sato, K | 1 |
| Niedzwiecki, D | 1 |
| Ye, X | 1 |
| Saltz, LB | 1 |
| Mayer, RJ | 1 |
| Mowat, RB | 1 |
| Whittom, R | 1 |
| Hantel, A | 1 |
| Benson, A | 1 |
| Atienza, D | 1 |
| Messino, M | 1 |
| Kindler, H | 1 |
| Venook, A | 1 |
| Hu, FB | 1 |
| Ogino, S | 1 |
| Wu, K | 1 |
| Willett, WC | 1 |
| Giovannucci, EL | 1 |
| Meyerhardt, JA | 1 |
| Fuchs, CS | 1 |
| Carvalho, Ddo C | 1 |
| Brigagão, MR | 1 |
| dos Santos, MH | 1 |
| de Paula, FB | 1 |
| Giusti-Paiva, A | 1 |
| Azevedo, L | 1 |
| Bessler, H | 1 |
| Salman, H | 1 |
| Bergman, M | 1 |
| Djaldetti, M | 1 |
| Magrini, R | 1 |
| Bhonde, MR | 1 |
| Hanski, ML | 1 |
| Notter, M | 1 |
| Scherübl, H | 1 |
| Boland, CR | 1 |
| Zeitz, M | 1 |
| Hanski, C | 1 |
| Takeshita, F | 1 |
| Ogawa, K | 1 |
| Asamoto, M | 1 |
| Shirai, T | 2 |
| Watanabe, F | 1 |
| Satsu, H | 1 |
| Mochizuki, T | 1 |
| Nakano, T | 1 |
| Shimizu, M | 1 |
| Ivanov, I | 1 |
| Lo, KC | 1 |
| Hawthorn, L | 1 |
| Cowell, JK | 1 |
| Ionov, Y | 1 |
| Merighi, S | 1 |
| Benini, A | 1 |
| Mirandola, P | 1 |
| Gessi, S | 1 |
| Varani, K | 1 |
| Simioni, C | 1 |
| Leung, E | 1 |
| Maclennan, S | 1 |
| Baraldi, PG | 1 |
| Borea, PA | 1 |
| Carter, O | 1 |
| Dashwood, RH | 2 |
| Wang, R | 2 |
| Dashwood, WM | 2 |
| Orner, GA | 1 |
| Fischer, KA | 2 |
| Löhr, CV | 2 |
| Pereira, CB | 2 |
| Bailey, GS | 2 |
| Williams, DE | 2 |
| Pandur, S | 1 |
| Pankiv, S | 1 |
| Johannessen, M | 1 |
| Moens, U | 1 |
| Huseby, NE | 1 |
| Louderback, M | 1 |
| Nakagama, H | 1 |
| Koval, TM | 1 |
| Boonkitticharoen, V | 1 |
| Laohathai, K | 1 |
| Puribhat, S | 1 |
| Vineis, P | 1 |
| Welfare, MR | 2 |
| Bassendine, MF | 1 |
| Daly, AK | 1 |
| Slattery, ML | 2 |
| Caan, BJ | 1 |
| Anderson, KE | 1 |
| Potter, JD | 1 |
| Yamagishi, S | 1 |
| Fujimori, H | 1 |
| Iwase, T | 1 |
| Hagiwara, A | 1 |
| Boonyaphiphat, P | 1 |
| Tanaka, H | 1 |
| Kawabe, M | 1 |
| Tamano, S | 1 |
| Kaneko, H | 1 |
| Matsui, M | 1 |
| Hirose, M | 1 |
| Ito, N | 1 |
| Tsuda, H | 1 |
| Sekine, K | 1 |
| Uehara, N | 1 |
| Takasuka, N | 1 |
| Moore, MA | 1 |
| Konno, Y | 1 |
| Nakashita, K | 1 |
| Degawa, M | 1 |
| Tunca, B | 1 |
| Egeli, U | 1 |
| Zorluoglu, A | 1 |
| Yilmazlar, T | 1 |
| Yerci, O | 1 |
| Kizil, A | 1 |
| West, DW | 1 |
| Robison, LM | 1 |
| French, TK | 1 |
| Ford, MH | 1 |
| Schuman, KL | 1 |
| Sorenson, AW | 1 |
| Heyden, S | 1 |
2 reviews available for caffeine and Colonic Neoplasms
| Article | Year |
|---|---|
Does drinking coffee reduce the risk of colorectal cancer? A qualitative umbrella review of systematic reviews.
Topics: Caffeine; Coffee; Colonic Neoplasms; Humans; Rectal Neoplasms; Risk Factors; Systematic Reviews as T | 2023 |
Dietary natural methylxanthines and colorectal cancer: a systematic review and meta-analysis.
Topics: Animals; Antineoplastic Agents; Caffeine; Colonic Neoplasms; Colorectal Neoplasms; Databases, Factua | 2020 |
2 trials available for caffeine and Colonic Neoplasms
| Article | Year |
|---|---|
Coffee Intake, Recurrence, and Mortality in Stage III Colon Cancer: Results From CALGB 89803 (Alliance).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Chemothera | 2015 |
Intake of fluids and methylxanthine-containing beverages: association with colon cancer.
Topics: Adult; Aged; Beverages; Caffeine; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Risk Factors | 1999 |
26 other studies available for caffeine and Colonic Neoplasms
| Article | Year |
|---|---|
Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p.
Topics: 1,2-Dimethylhydrazine; Animals; Caffeine; Carcinogenesis; Chlorogenic Acid; Coffee; Colon; Colonic N | 2022 |
Caffeine-Supplemented Diet Prevents Fatigue-Like Behavior in Tumor-Bearing Mice.
Topics: Animals; Caffeine; Colonic Neoplasms; Diet; Fatty Acids, Nonesterified; Hypoglycemia; Liver Glycogen | 2023 |
Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer.
Topics: Adenocarcinoma; Caffeine; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; D | 2023 |
Forecasting Chronic Diseases Using Data Fusion.
Topics: Acute Coronary Syndrome; Biomarkers; Breast Neoplasms; Caffeine; Chromatography, Liquid; Chronic Dis | 2017 |
Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells.
Topics: Caffeine; Cellular Senescence; Colonic Neoplasms; DNA Damage; Down-Regulation; Doxorubicin; HCT116 C | 2018 |
Increased expression and possible role of chitinase 3-like-1 in a colitis-associated carcinoma model.
Topics: Adipokines; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Caffeine; Chitinase-3-Like P | 2014 |
Organic and conventional Coffea arabica L.: a comparative study of the chemical composition and physiological, biochemical and toxicological effects in Wistar rats.
Topics: Alkaloids; Animals; Anticarcinogenic Agents; Antioxidants; Behavior, Animal; Body Weight; Caffeine; | 2011 |
Caffeine alters cytokine secretion by PBMC induced by colon cancer cells.
Topics: Caffeine; Cell Communication; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Cytokines; | 2012 |
Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Blotting, Western; Caffeine; Camptothecin; Carrier | 2002 |
Mechanistic approach of contrasting modifying effects of caffeine on carcinogenesis in the rat colon and mammary gland induced with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Body Weight; Breast; Bromodeoxyuridine; | 2003 |
Development of the method for evaluating protective effect of food factors on THP-1-induced damage to human intestinal Caco-2 monolayers.
Topics: Caffeine; Cell Line; Cell Line, Tumor; Cell Survival; Coculture Techniques; Colonic Neoplasms; Human | 2004 |
Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells.
Topics: Caffeine; Codon, Nonsense; Colonic Neoplasms; DNA Mutational Analysis; Gene Expression Regulation, N | 2007 |
Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.
Topics: Adenosine; Caffeine; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Extracellular | 2007 |
Comparison of white tea, green tea, epigallocatechin-3-gallate, and caffeine as inhibitors of PhIP-induced colonic aberrant crypts.
Topics: Animals; Anticarcinogenic Agents; Caffeine; Carcinogens; Catechin; Cell Division; Colon; Colonic Neo | 2007 |
Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells.
Topics: Animals; Caffeine; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Cycloheximide; Dactinomycin; gamm | 2007 |
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.
Topics: Animals; Anticarcinogenic Agents; beta Catenin; Caffeine; Carcinogens; Catechin; Colonic Neoplasms; | 2008 |
Selective inhibition of replicative and repair DNA synthesis in mouse colon following administration of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Caffeine; Colonic Neoplasms; Digestive System; Dimethylhydrazines; D | 1984 |
Differential radiosensitization of radioresistant human cancer cells by caffeine.
Topics: Adenocarcinoma; Caffeine; Carcinoma, Hepatocellular; Colonic Neoplasms; Gamma Rays; Humans; Radiatio | 1993 |
Hypothesis: coffee consumption, N-acetyltransferase phenotype, and cancer.
Topics: Acetylation; Arylamine N-Acetyltransferase; Breast Neoplasms; Caffeine; Coffee; Colonic Neoplasms; F | 1993 |
Caffeine phenotyping in patients with familial adenomatous polyposis may shed light on sporadic colon cancer and acetylator status.
Topics: Acetylation; Adenomatous Polyposis Coli; Caffeine; Colonic Neoplasms; Humans; Phenotype; Risk Factor | 1996 |
Caffeine-assisted chemotherapy for colonic leiomyosarcoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Colonic Neoplasms; Doxorubicin; | 1999 |
Organ-dependent modifying effects of caffeine, and two naturally occurring antioxidants alpha-tocopherol and n-tritriacontane-16,18-dione, on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary and colonic carcinogenesis in female F344
Topics: Adenocarcinoma; Adenoma; Animals; Antioxidants; Caffeine; Carcinogens; Chemoprevention; Colonic Neop | 1999 |
Heterocyclic amine mixture carcinogenesis and its enhancement by caffeine in F344 rats.
Topics: Animals; Caffeine; Carcinogens; Colonic Neoplasms; Drug Synergism; Imidazoles; Liver Neoplasms, Expe | 1999 |
The expression frequency of common fragile sites and genetic predisposition to colon cancer.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Alu Elements; Aphidicolin; Bromodeoxyuridine; Caffeine; Chi | 2000 |
Tobacco, alcohol, coffee, and caffeine as risk factors for colon cancer in a low-risk population.
Topics: Adult; Aged; Alcohol Drinking; Caffeine; Case-Control Studies; Christianity; Coffee; Colonic Neoplas | 1990 |
[Editorial: Caffeine in the prisoner's dock--Quousque tandem?].
Topics: Adult; Caffeine; Coffee; Colonic Neoplasms; Female; Humans; Liver Diseases; Male; Middle Aged; Recta | 1974 |