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caffeine and Colicky Pain

caffeine has been researched along with Colicky Pain in 9 studies

Research Excerpts

ExcerptRelevanceReference
" Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine."6.55Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017)
" The global incidence of adverse events was 45% higher with EC, though not significant (32 vs."2.69Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks. ( Geraud, G; Gómez, JP; Henry, P; Joffroy, A; Lainez, JM; Le Jeunne, C; Liaño, H; Pradalier, A; Titus i Albareda, F, 1999)
" Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine."2.55Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017)
"Effects of binge drinking on GI symptoms were strongest when comparing between individuals (rather than within individuals)."1.39Relationship between patterns of alcohol consumption and gastrointestinal symptoms among patients with irritable bowel syndrome. ( Cain, KC; Eugenio, MD; Heitkemper, MM; Jarrett, ME; Reding, KW, 2013)
" In this work, the antinociceptive and toxic effects of two new coordination complexes: Cu₂(fen)₄(caf)₂ [fen: fenoprofenate anion; caf: caffeine] and Cu₂(fen)₄(dmf)₂ [dmf: N-N'-dimethylformamide] were evaluated in mice."1.38Anti-nociceptive activity and toxicity evaluation of Cu(II)-fenoprofenate complexes in mice. ( Agotegaray, M; Bras, C; Gandini, NA; Gumilar, F; Minetti, A; Quinzani, O, 2012)
"Prevalence of headache, stomachache, backache, and morning fatigue."1.32Headache, stomachache, backache, and morning fatigue among adolescent girls in the United States: associations with behavioral, sociodemographic, and environmental factors. ( Ghandour, RM; Huang, ZJ; Kogan, MD; Overpeck, MD; Scheidt, PC, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lipton, RB1
Diener, HC1
Robbins, MS1
Garas, SY1
Patel, K1
Wilson, PB1
Kromhout, HE1
Landstra, AM1
van Luin, M1
van Setten, PA1
de Wijkerslooth, LR1
Koch, BC1
Malingré, MM1
Smits, P1
Bartelink, AK1
Gumilar, F1
Agotegaray, M1
Bras, C1
Gandini, NA1
Minetti, A1
Quinzani, O1
Reding, KW1
Cain, KC1
Jarrett, ME1
Eugenio, MD1
Heitkemper, MM1
Ghandour, RM1
Overpeck, MD1
Huang, ZJ1
Kogan, MD1
Scheidt, PC1
Kueper, T1
Martinelli, D1
Konetzki, W1
Stamerjohn, RW1
Magill, JB1
Le Jeunne, C1
Gómez, JP1
Pradalier, A1
Titus i Albareda, F1
Joffroy, A1
Liaño, H1
Henry, P1
Lainez, JM1
Geraud, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acute Headache Treatment in Pregnancy: Improvement in Pain Scores With Occipital Nerve Block vs PO Acetaminophen With Caffeine A Randomized Controlled Trial[NCT03951649]Phase 462 participants (Actual)Interventional2020-02-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Headache Free Period at 7 Days

(NCT03951649)
Timeframe: 7 days

Interventiondays (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group1

Number of Participants With Development of Hypertensive Disease of Pregnancy Within 28 Days

(NCT03951649)
Timeframe: 28 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block9
Oral Acetaminophen/Caffeine Group4

Number of Participants With Development of Hypertensive Disease of Pregnancy Within 7 Days

(NCT03951649)
Timeframe: 7 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block7
Oral Acetaminophen/Caffeine Group2

Number of Participants With Injection Site Complication (Infection, Hematoma, and Ecchymosis)

Other: Pain at injection site (NCT03951649)
Timeframe: 7 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block0
Oral Acetaminophen/Caffeine Group2

Number of Participants With Need for Admission for Treatment of Headache

(NCT03951649)
Timeframe: 7 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block0
Oral Acetaminophen/Caffeine Group0

Number of Participants With Need for Crossover Treatment

(NCT03951649)
Timeframe: 4 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block9
Oral Acetaminophen/Caffeine Group14

Number of Participants With Need for Neurology Consult

(NCT03951649)
Timeframe: 5 hours

InterventionParticipants (Count of Participants)
Occipital Nerve Block4
Oral Acetaminophen/Caffeine Group2

Number of Participants With Need for Representation for Treatment of Headache With 28 Days

Emergency department for treatment of headache since treatment asked at 28 day follow up (NCT03951649)
Timeframe: 28 days

InterventionParticipants (Count of Participants)
Occipital Nerve Block5
Oral Acetaminophen/Caffeine Group1

Number of Participants With Need for Second Line Treatment

(NCT03951649)
Timeframe: 120 min

InterventionParticipants (Count of Participants)
Occipital Nerve Block5
Oral Acetaminophen/Caffeine Group5

Number of Participants With Response to Occipital Nerve Block in Pregnancy

Based on guidelines from the International Headache Society the primary outcome is the portion of women who experience resolution of headache or improvement of headache to mild range (VRS ≤ 3) at 2 hours following treatment with Occipital nerve block as compared to acetaminophen/caffeine cocktail. (NCT03951649)
Timeframe: 60-300 min

InterventionParticipants (Count of Participants)
Occipital Nerve Block20
Oral Acetaminophen/Caffeine Group16

Response to Cross Over Treatment at 60 Min

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 60 min

Interventionscore on a scale (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group3

Response to Second Line Treatment at 60 Min

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 180min

Interventionscore on a scale (Median)
Occipital Nerve Block6
Oral Acetaminophen/Caffeine Group4

Response to Treatment Within 2 Hours

"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 2 hrs

Interventionscore on a scale (Median)
Occipital Nerve Block6.0
Oral Acetaminophen/Caffeine Group6.5

Reviews

1 review available for caffeine and Colicky Pain

ArticleYear
Caffeine in the management of patients with headache.
    The journal of headache and pain, 2017, Oct-24, Volume: 18, Issue:1

    Topics: Abdominal Pain; Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Central Nervous System Stimulan

2017

Trials

1 trial available for caffeine and Colicky Pain

ArticleYear
Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks.
    European neurology, 1999, Volume: 41, Issue:1

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Th

1999

Other Studies

7 other studies available for caffeine and Colicky Pain

ArticleYear
Dietary and non-dietary correlates of gastrointestinal distress during the cycle and run of a triathlon.
    European journal of sport science, 2016, Volume: 16, Issue:4

    Topics: Abdominal Pain; Adult; Caffeine; Diet; Dietary Carbohydrates; Energy Intake; Female; Flatulence; Gas

2016
[Acute caffeine intoxication after intake of 'herbal energy capsules'].
    Nederlands tijdschrift voor geneeskunde, 2008, Jul-12, Volume: 152, Issue:28

    Topics: Abdominal Pain; Adolescent; Caffeine; Central Nervous System Stimulants; Dietary Supplements; Drug O

2008
[Acute caffeine intoxication after intake of 'herbal energy capsules'].
    Nederlands tijdschrift voor geneeskunde, 2008, Oct-18, Volume: 152, Issue:42

    Topics: Abdominal Pain; Caffeine; Central Nervous System Stimulants; Dietary Supplements; Female; Humans; Hy

2008
Anti-nociceptive activity and toxicity evaluation of Cu(II)-fenoprofenate complexes in mice.
    European journal of pharmacology, 2012, Jan-30, Volume: 675, Issue:1-3

    Topics: Abdominal Pain; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arousal; Caffeine; Cen

2012
Relationship between patterns of alcohol consumption and gastrointestinal symptoms among patients with irritable bowel syndrome.
    The American journal of gastroenterology, 2013, Volume: 108, Issue:2

    Topics: Abdominal Pain; Adult; Alcohol Drinking; Binge Drinking; Caffeine; Case-Control Studies; Coffee; Con

2013
Headache, stomachache, backache, and morning fatigue among adolescent girls in the United States: associations with behavioral, sociodemographic, and environmental factors.
    Archives of pediatrics & adolescent medicine, 2004, Volume: 158, Issue:8

    Topics: Abdominal Pain; Adolescent; Adolescent Behavior; Alcohol Drinking; Back Pain; Caffeine; Comorbidity;

2004
Identification of problem foods using food and symptom diaries.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1995, Volume: 112, Issue:3

    Topics: Abdominal Pain; Adult; Caffeine; Child; Diet Records; Eating; Ethanol; Fatigue; Feeding Behavior; Fe

1995