Page last updated: 2024-10-24

caffeine and Cleft Palate

caffeine has been researched along with Cleft Palate in 11 studies

Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.

Research Excerpts

ExcerptRelevanceReference
"Moderate caffeine intake during pregnancy is common, but little is known about its potential association with birth defects."7.75Maternal caffeine intake during pregnancy and orofacial clefts. ( Browne, ML; Collier, SA; Honein, MA; Rasmussen, SA, 2009)
" Maternal consumption of coffee and other caffeine-containing beverages in early pregnancy was recorded shortly after birth."3.75Maternal consumption of coffee and caffeine-containing beverages and oral clefts: a population-based case-control study in Norway. ( Andersen, LF; Drevon, CA; Johansen, AM; Lie, RT; Wilcox, AJ, 2009)
"Moderate caffeine intake during pregnancy is common, but little is known about its potential association with birth defects."3.75Maternal caffeine intake during pregnancy and orofacial clefts. ( Browne, ML; Collier, SA; Honein, MA; Rasmussen, SA, 2009)
"Dose-response of the teratogenic effect of caffeine (CA) and the potential role of facial hematomas in the pathogenesis of caffeine-induced cleft palate were investigated using CD1 mice treated with 150, 200, or 250 mg CA/kg i."3.69Interaction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice. ( Brimer, GE; Fraipier, BL; Frappier, BL; Reddy, CS; Reddy, RV, 1994)
"1 In Charles River CD1 mice, a single dose of 100 mg kg-1 caffeine injected intraperitoneally on day 14 of pregnancy caused a low incidence of cleft palate in the fetuses."3.66Acute studies to investigate the mechanism of action of caffeine as a teratogen in mice. ( Elmazar, MM; McElhatton, PR; Sullivan, FM, 1981)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Charoenvicha, C1
Wongkawinwoot, K1
Sirikul, W1
Khwanngern, K1
Sirimaharaj, W1
de Andrade, RS1
Oliveira, FES1
Martelli, DRB1
de Barros, LM1
Martelli JĂșnior, H1
Kumar, M1
Chawla, R1
Haloi, P1
Singh, M1
Johansen, AM1
Wilcox, AJ1
Lie, RT1
Andersen, LF1
Drevon, CA1
Collier, SA1
Browne, ML1
Rasmussen, SA1
Honein, MA1
Rosenberg, L1
Mitchell, AA1
Shapiro, S1
Slone, D1
Elmazar, MM1
McElhatton, PR1
Sullivan, FM1
Reddy, RV1
Reddy, CS1
Frappier, BL1
Brimer, GE1
Fraipier, BL1
Zawoiski, EJ1
York, RG1
Randall, JL1
Scott, WJ1
Fujii, T1
Sasaki, H1
Nishimura, H1

Trials

1 trial available for caffeine and Cleft Palate

ArticleYear
Selected birth defects in relation to caffeine-containing beverages.
    JAMA, 1982, Mar-12, Volume: 247, Issue:10

    Topics: Abnormalities, Drug-Induced; Beverages; Caffeine; Cleft Lip; Cleft Palate; Clinical Trials as Topic;

1982

Other Studies

10 other studies available for caffeine and Cleft Palate

ArticleYear
Predisposing factors of non-syndromic cleft lip and cleft palate in the northern Thai population: A 10-year retrospective case-control study.
    Congenital anomalies, 2023, Volume: 63, Issue:5

    Topics: Caffeine; Case-Control Studies; Causality; Child; Cleft Lip; Cleft Palate; Female; Humans; Maternal

2023
Maternal consumption of caffeine and second-hand tobacco smoke as risk factors for the development of oral clefts.
    Clinics (Sao Paulo, Brazil), 2023, Volume: 78

    Topics: Caffeine; Case-Control Studies; Child; Child, Preschool; Cleft Lip; Cleft Palate; Female; Folic Acid

2023
The use of caffeine for the treatment of apnea of prematurity and bradycardia in a holoprosencephalic child with cleft lip and palate.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:8

    Topics: Apnea; Bradycardia; Caffeine; Central Nervous System Stimulants; Citrates; Cleft Lip; Cleft Palate;

2013
Maternal consumption of coffee and caffeine-containing beverages and oral clefts: a population-based case-control study in Norway.
    American journal of epidemiology, 2009, May-15, Volume: 169, Issue:10

    Topics: Caffeine; Case-Control Studies; Cleft Lip; Cleft Palate; Coffee; Confidence Intervals; Female; Healt

2009
Maternal caffeine intake during pregnancy and orofacial clefts.
    Birth defects research. Part A, Clinical and molecular teratology, 2009, Volume: 85, Issue:10

    Topics: Adult; Caffeine; Case-Control Studies; Cleft Lip; Cleft Palate; Female; Humans; Infant, Newborn; Pha

2009
Acute studies to investigate the mechanism of action of caffeine as a teratogen in mice.
    Human toxicology, 1981, Volume: 1, Issue:1

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex; Amniotic Fluid; Animals; Caffeine; Cleft Palate; Cortic

1981
Interaction of dimethylsulfoxide and arachidonic acid with the teratogenic effects of caffeine in mice.
    Natural toxins, 1994, Volume: 2, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Arachidonic Acid; Caffeine; Cleft Palate; Corticosterone; Dime

1994
Prevention of caffeine-induced cleft palate by L-glutamic acid.
    Toxicology and applied pharmacology, 1976, Volume: 35, Issue:1

    Topics: Animals; Body Weight; Caffeine; Cleft Palate; Diet; Feeding Behavior; Female; Fetus; Glutamates; Mic

1976
Teratogenicity of paraxanthine (1,7-dimethylxanthine) in C57BL/6J mice.
    Teratology, 1986, Volume: 34, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cleft Palate; Dose-Response Relationship, Drug; Fema

1986
Teratogenicity of caffeine in mice related to its mode of administration.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cleft Palate; Clubfoot; Dyspnea; Fingers; Gestationa

1969