Page last updated: 2024-10-24

caffeine and Chronic Insomnia

caffeine has been researched along with Chronic Insomnia in 104 studies

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that caffeine can either induce or reduce neuropsychiatric symptoms in individual patients with dementia."9.01Caffeine and neuropsychiatric symptoms in patients with dementia: A systematic review. ( Achterberg, WP; Giltay, E; Kromhout, MA; Numans, ME; Rius Ottenheim, N, 2019)
"This study investigates whether inhalation of different fractions of lavender essential oil can attenuate the sleep disturbances induced by combined anxiety and caffeine and explores the underlying mechanisms."8.31Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice. ( Han, T; Liu, F; Ma, L; Wang, W; Xu, Y; Yang, S; Yao, L, 2023)
"Caffeine is known to improve concentration and reduce fatigue in healthy adults, but high doses may induce anxiety and agitation."7.80Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study. ( Achterberg, WP; Jongerling, J; Kromhout, MA, 2014)
"In a cross-sectional study of 4558 Australians, it was found that the proportion of subjects reporting indigestion, palpitations, tremor, headache and insomnia increased significantly with mean caffeine intake."7.67A study of caffeine consumption and symptoms; indigestion, palpitations, tremor, headache and insomnia. ( Mathers, CD; Shirlow, MJ, 1985)
"Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation."5.48Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018)
"Abstinence from smoking increases blood levels of caffeine and may potentiate the ability of caffeine to increase anxiety, insomnia, etc."5.09Effect of smoking abstinence on the subjective effects of caffeine. ( Dominick, A; Hughes, JR; Liguori, A; MacLaughlin, M, 1999)
"These findings suggest that caffeine can either induce or reduce neuropsychiatric symptoms in individual patients with dementia."5.01Caffeine and neuropsychiatric symptoms in patients with dementia: A systematic review. ( Achterberg, WP; Giltay, E; Kromhout, MA; Numans, ME; Rius Ottenheim, N, 2019)
" However, caffeine at high doses can increase anxiety, insomnia, calcium loss and possibly the risk of fractures."4.89Coffee and tea: perks for health and longevity? ( Bhatti, SK; Lavie, CJ; O'Keefe, JH, 2013)
"This study investigates whether inhalation of different fractions of lavender essential oil can attenuate the sleep disturbances induced by combined anxiety and caffeine and explores the underlying mechanisms."4.31Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice. ( Han, T; Liu, F; Ma, L; Wang, W; Xu, Y; Yang, S; Yao, L, 2023)
"3% of children had at least 1 caregiver-reported sleep problem (66% insomnia symptoms, 64% electronics, 38% insufficient sleep, 21% caffeine, 17% snoring)."4.31Discrepancies Between Caregiver Reported Early Childhood Sleep Problems and Clinician Documentation and Referral. ( Bhandari, E; Carson, M; Cicalese, O; Fiks, AG; Mindell, JA; Stefanovski, D; Williamson, AA, 2023)
"Caffeine is known to improve concentration and reduce fatigue in healthy adults, but high doses may induce anxiety and agitation."3.80Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study. ( Achterberg, WP; Jongerling, J; Kromhout, MA, 2014)
" Self-medication for pain or common cold symptoms was reported by 54% while 8% had taken caffeine tablets or other stimulants."3.73Self-medication among Finnish young men in the beginning of common military service. ( Jormanainen, V; Linden, K; Pietilä, K; Swigonski, NL, 2005)
"In a cross-sectional study of 4558 Australians, it was found that the proportion of subjects reporting indigestion, palpitations, tremor, headache and insomnia increased significantly with mean caffeine intake."3.67A study of caffeine consumption and symptoms; indigestion, palpitations, tremor, headache and insomnia. ( Mathers, CD; Shirlow, MJ, 1985)
"This clinical study of 62 patients with restless legs syndrome and associated anxious-depressed and other clinical states seems to indicate that caffeine is the major etiological factor in the causation of the restless legs syndrome."3.66Restless legs, anxiety and caffeinism. ( Lutz, EG, 1978)
"We considered sleep disturbances (insomnia symptoms, sleep quality), sleep health dimensions (duration, satisfaction, efficiency, timing, daytime alertness), circadian characteristics (chronotype)."3.01A systematic review and meta-analysis of the association between young adults' sleep habits and substance use, with a focus on self-medication behaviours. ( Bacaro, V; Baglioni, C; Curati, S; Gelfo, F; Martoni, M; Meneo, D; Russo, PM, 2023)
"Sleep or sleepiness was measured objectively in 46% of studies (n = 16)."2.82The Impact of Dietary Factors on the Sleep of Athletically Trained Populations: A Systematic Review. ( Aisbett, B; Barnard, J; Condo, D; Lastella, M; Roberts, S, 2022)
" The ingestion of low to moderate doses of caffeinated energy drinks has been associated with adverse side effects such as insomnia or increased nervousness."2.79The use of energy drinks in sport: perceived ergogenicity and side effects in male and female athletes. ( Abian-Vicen, J; Areces, F; Del Coso, J; Gallo-Salazar, C; Gonzalez-Millán, C; Lara, B; Ruiz-Vicente, D; Salinero, JJ, 2014)
" This study assessed the effects of caffeine on sleep architecture and electroencephalography (EEG) spectrum alone and in combination with two different sleep-promoting medications."2.74Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers. ( Hutson, PH; Ivarsson, M; Nutt, DJ; Paterson, LM; Wilson, SJ, 2009)
"Insomnia is a common and disabling complaint for which there is a need for improved treatments."2.73A translational, caffeine-induced model of onset insomnia in rats and healthy volunteers. ( Hutson, PH; Ivarsson, M; Nutt, DJ; Paterson, LM; Wilson, SJ, 2007)
"Experimental sleep disturbances (model insomnia) were produced by the administration of methylphenidate (MPD) 10 mg and caffeine (CAF) 150 mg."2.65Model insomnia by methylphenidate and caffeine and use in the evaluation of temazepam. ( Matsue, Y; Matsuoka, H; Okuma, T; Toyomura, K, 1982)
"The prevalence of the insomnia syndrome and the effects of caffeine on sleep are in part genetically determined."2.53[Self-rated Caffeine Sensitivity: Implications for Personalized Sleep Medicine?]. ( Landolt, HP, 2016)
"Models of sleep physiology and insomnia are discussed, along with the potential implications for the chronification of migraine and tension-type headache."2.48Chronic headaches and insomnia: working toward a biobehavioral model. ( Ong, JC; Park, M, 2012)
"Caffeine is a stimulant of central nervous system and therefore is probably the most commonly used psychoactive substance in the world."2.48[Caffeine--common ingredient in a diet and its influence on human health]. ( Wierzejska, R, 2012)
"Nicotine has a biphasic effect on sleep: at low concentrations, it leads to relaxation and sedation and at high concentrations inhibits sleep."2.39[Prevention and treatment of sleep disorders through regulation] of sleeping habits]. ( Bailly, D; Onen, F; Onen, SH; Parquet, P, 1994)
"The overall efficacy of Jiaotai Pill combined with head massage therapy consistent with 5-tone rhythm is significantly better than that of traditional massage combined with 5-element music therapy for insomnia patients with heart-kidney disharmony."1.91Clinical study of "Jiaotai Pill" combined with head massage with 5-tone rhythm on insomnia patients of heart-kidney disharmony type. ( Guan, R; Li, J; Liu, Z; Pan, L; Shi, Q; Yu, Z, 2023)
"Caffeine use was related to shorter average total sleep time and more variability in sleep efficiency."1.91Using a frequentist and Bayesian approach to examine video game usage, substance use, and sleep among college students. ( Asbee, J; Dietch, JR; Slavish, D; Taylor, DJ, 2023)
"Increased substance use was reported by 30%, including increased alcohol (13."1.91COVID-19 Pandemic Responses among National Guard Service Members: Stressors, Coping Strategies, Sleep Difficultiesand Substance Use. ( Fullerton, CS; Mash, HBH; Morganstein, JC; Ursano, RJ, 2023)
"Caffeine was consumed by 91."1.72Caffeine Intake among Undergraduate Students: Sex Differences, Sources, Motivations, and Associations with Smoking Status and Self-Reported Sleep Quality. ( Martínez, S; Moir, HJ; Riera-Sampol, A; Rodas, L; Tauler, P, 2022)
"A murine insomnia model was created by caffeine."1.72Prolonging effects of Valeriana fauriei root extract on pentobarbital-induced sleep in caffeine-induced insomnia model mice and the pharmacokinetics of its active ingredients under conditions of glycerol fatty acid ester as emulsifiers. ( Maki, Y; Makino, T; Ota, M; Xu, LY, 2022)
"26."1.72Sleep Disorders and Future Diagnosis of Parkinsonism: A Prospective Study Using the Canadian Longitudinal Study on Aging. ( Pelletier, A; Postuma, RB; Wolfson, C; Yao, CW; Zolfaghari, S, 2022)
"In the caffeine-induced insomnia model, the administration of a Saaz-Saphir mixture increased the sleep time compared to Saaz or Saphir administration alone, which was attributed to the increase in NREM sleep time by the δ-wave increase."1.62GABA ( Ahn, Y; Cho, HJ; Jo, K; Kwak, WK; Min, B; Suh, HJ, 2021)
"Caffeine consumption has been linked to poor sleep health in adolescents, but it is unknown whether poor sleep predicts caffeine consumption, and/or whether caffeine consumption predicts poor sleep, particularly when sleep is measured objectively."1.62Too Jittery to Sleep? Temporal Associations of Actigraphic Sleep and Caffeine in Adolescents. ( Buxton, OM; Chang, AM; Hale, L; Master, L; Mathew, GM; Reichenberger, DA, 2021)
"Insomnia is one of the most common sleep disorders and is difficult to completely treat because of the undesirable side effects of hypnotics."1.62Acupuncture stimulation at HT7 as a non-pharmacological therapy for sleep disorder caused by caffeine administration in rats. ( Bang, SK; Choi, KH; Kang, SY; Kwon, OS; Moon, JY; Ryu, Y; Seo, SY, 2021)
"Patients with either chronic fatigue or insomnia who underwent polysomnography as standardized clinical assessment were included in a retrospective study."1.56Retrospective Analysis of Risk Factors for Periodic Limb Movements in a Large Cohort of Insomnia and Chronic Fatigue Patients. ( Delesie, L; Desmet, O; Hanoulle, I; Mariman, A; Pevernagie, D; Tobback, E; Vogelaers, D, 2020)
"Mean caffeine consumption was 624 mg per week, and 80."1.48Evening use of caffeine moderates the relationship between caffeine consumption and subjective sleep quality in students. ( Antypa, N; Kerpershoek, ML; Van den Berg, JF, 2018)
"Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation."1.48Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018)
"Caffeine-induced insomnia increased with aging in both men and women."1.48Distinct sensitivity to caffeine-induced insomnia related to age. ( Cunha, RA; de Carvalho, HW; Frozi, J; Lara, DR; Ottoni, GL, 2018)
"Common risk factors for insomnia were included in the adjusted analyses."1.46Insomnia complaints and substance use in German adolescents: did we underestimate the role of coffee consumption? Results of the KiGGS study. ( Cohrs, S; Dueck, A; Goerke, M; Lange, K; Schlack, R; Skarupke, C; Szagun, B; Thome, J, 2017)
"Caffeine after dinner was associated with increased adjusted odds of a poorer score for Pittsburgh Sleep Quality Index-evaluated daytime dysfunction (P=."1.46Gender differences in sleep hygiene practices and sleep quality in New Zealand adolescents aged 15 to 17 years. ( Galland, BC; Gray, AR; Lobb, C; Penno, J; Smith, C; Taylor, RW, 2017)
"Caffeineinduced insomnia wild-type Drosophila and short-sleep mutant flies minisleep (mns) and Hyperkinetic(Y) (Hk(Y)) were used to assess the hypnotic effects of the AIF in vivo."1.43Hypnotic effects of a novel anti-insomnia formula on Drosophila insomnia model. ( Chan, EH; Fung, KP; Ko, CH; Koon, CM; Lau, CB; Lee, KY; Leung, PC; Wing, YK; Yu, SL, 2016)
" Following recovery, animals were dosed with caffeine (10 mg/kg) alone or in combination with zolpidem (10 mg/kg) or trazodone (20 mg/kg)."1.35Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption. ( Hutson, PH; Ivarsson, M; Nutt, DJ; Paterson, LM; Wilson, SJ, 2009)
"A 2 x 2 (Worry x Induced sleeplessness) analysis of covariance design was used."1.34Night-time thoughts in high and low worriers: reaction to caffeine-induced sleeplessness. ( Bjorvatn, B; Nordhus, IH; Omvik, S; Pallesen, S; Thayer, J, 2007)
"Additional adjustment for insomnia, cognitive function, depressed mood, midlife cigarette smoking and coffee drinking, and other factors failed to alter the association between EDS and PD (OR = 2."1.33Excessive daytime sleepiness and subsequent development of Parkinson disease. ( Abbott, RD; Curb, JD; Masaki, KH; Nelson, JS; Petrovitch, H; Ross, GW; Tanner, CM; White, LR, 2005)
"We hypothesized that insomniacs would be more affected by caffeine, which would suggest a change in adenosine receptor (number or sensitivity) in primary insomniacs."1.33Caffeine challenge in insomniac patients after total sleep deprivation. ( Campos, RM; Castaño, A; Salín-Pascual, RJ; Shiromani, PJ; Valencia-Flores, M, 2006)
"Eleven healthy individuals without insomnia scoring low (4 women, mean age=32."1.33Stress-related sleep disturbance and polysomnographic response to caffeine. ( Drake, CL; Jefferson, C; Roehrs, T; Roth, T, 2006)
"Caffeine was administered intraperitoneally at the beginning of a sleep period."1.32A kinetic approach to caffeine--Coffea cruda interaction. ( Cortés-Galván, L; Juárez-G, FM; Pérez-Ordaz, L; Ruiz-Vega, G, 2003)
"Although some women with insomnia limit or refrain from caffeine and alcohol intake, many have not optimized behaviors believed to help prevent or modulate insomnia."1.32Variations in sleep hygiene practices of women with and without insomnia. ( Cheek, RE; Lentz, MJ; Shaver, JL, 2004)
"Subjective insomnia is more prevalent in elderly than in young populations."1.29Is caffeine a factor in subjective insomnia of elderly people? ( Curless, R; French, JM; James, OF; Wynne, HA, 1993)
"Pharmacokinetic and pharmacodynamic responses to caffeine (2."1.29Pharmacokinetic and pharmacodynamic responses to caffeine in poor and normal sleepers. ( Ashton, H; Kamali, F; Marsh, R; Tiffin, P, 1995)
"The association of three subtypes of insomnia with psychic and functional syndromes, and the course of insomnia over 7 years were examined in a Swiss cohort of young adults interviewed three times."1.28The Zurich study. VIII. Insomnia: association with depression, anxiety, somatic syndromes, and course of insomnia. ( Angst, J; Vollrath, M; Wicki, W, 1989)
" Differences among high, moderate and low users were common, and some dose-response associations were apparent."1.26Somatic manifestations of caffeinism. ( Greden, JF; Lubetsky, M; Victor, BS, 1981)
"Caffeine 'insomnia' thus seems characterized by increased stability of wakefulness, and hypnotic withdrawal 'insomnia' by decreased stability fo sleep."1.25Two types of insomnia: too much waking or not enough sleep. ( Brezinová, V; Loudon, J; Oswald, I, 1975)

Research

Studies (104)

TimeframeStudies, this research(%)All Research%
pre-199020 (19.23)18.7374
1990's8 (7.69)18.2507
2000's21 (20.19)29.6817
2010's28 (26.92)24.3611
2020's27 (25.96)2.80

Authors

AuthorsStudies
Zolfaghari, S1
Yao, CW1
Wolfson, C1
Pelletier, A1
Postuma, RB1
Kim, E1
Robinson, NM1
Newman, BM1
Romdhani, M1
Rae, DE1
Nédélec, M1
Ammar, A1
Chtourou, H1
Al Horani, R1
Ben Saad, H1
Bragazzi, N1
Dönmez, G1
Driss, T1
Fullagar, HHK1
Farooq, A1
Garbarino, S1
Hammouda, O1
Hassanmirzaei, B1
Khalladi, K1
Khemila, S1
Mataruna-Dos-Santos, LJ1
Moussa-Chamari, I1
Mujika, I1
Muñoz Helú, H1
Norouzi Fashkhami, A1
Paineiras-Domingos, LL1
Rahbari Khaneghah, M1
Saita, Y1
Trabelsi, K1
Vitale, JA1
Washif, JA1
Weber, J1
Souissi, N1
Taylor, L1
Chamari, K1
Min, B1
Ahn, Y1
Cho, HJ1
Kwak, WK1
Suh, HJ1
Jo, K1
Mathew, GM1
Reichenberger, DA1
Master, L1
Buxton, OM1
Chang, AM1
Hale, L1
Ma, Z1
Chen, XY1
Wang, D1
Zhu, Z1
Niu, H1
Huang, S1
Zhou, X1
Yang, Z1
Fan, F1
Riera-Sampol, A1
Rodas, L1
Martínez, S1
Moir, HJ1
Tauler, P1
Kim, H1
Park, I1
Park, K1
Park, S1
Kim, YI1
Park, BG1
Ota, M1
Maki, Y1
Xu, LY1
Makino, T1
Barnard, J1
Roberts, S1
Lastella, M1
Aisbett, B1
Condo, D1
Inoue, E1
Suzuki, T1
Nakayama, T1
Yoshimura, T1
Sudo, K1
Shimizu, Y1
Iwaki, Y1
Kawasaki, H1
Ishida, N1
Xu, Y1
Ma, L1
Liu, F1
Yao, L1
Wang, W1
Yang, S1
Han, T1
Guan, R1
Pan, L1
Yu, Z1
Liu, Z1
Shi, Q1
Li, J1
Carson, M1
Cicalese, O1
Bhandari, E1
Stefanovski, D1
Fiks, AG1
Mindell, JA1
Williamson, AA1
Asbee, J1
Slavish, D1
Taylor, DJ2
Dietch, JR1
Chabal, S1
Folstein, JR1
Chinoy, ED1
Markwald, RR1
Lieberman, HR1
Kapellou, A1
King, A1
Graham, CAM1
Pilic, L1
Mavrommatis, Y1
Mash, HBH1
Morganstein, JC1
Fullerton, CS1
Ursano, RJ1
Meneo, D1
Bacaro, V1
Curati, S1
Russo, PM1
Martoni, M1
Gelfo, F1
Baglioni, C1
Tobback, E1
Desmet, O1
Hanoulle, I1
Delesie, L1
Pevernagie, D1
Vogelaers, D1
Mariman, A1
Erblang, M1
Drogou, C1
Gomez-Merino, D1
Metlaine, A1
Boland, A1
Deleuze, JF1
Thomas, C1
Sauvet, F1
Chennaoui, M1
Young, DR1
Sidell, MA1
Grandner, MA2
Koebnick, C1
Troxel, W1
Hu, Y1
Stephenson, K1
Klare, D1
Choi, J1
Irish, LA1
Mead, MP1
Cao, L1
Veronda, AC1
Crosby, RD1
Chaudhary, NS1
Taylor, BV1
Troxel, WM1
Chakravorty, S1
Bodur, M1
Baspinar, B1
Özçelik, AÖ1
Seo, SY1
Moon, JY1
Kang, SY1
Kwon, OS1
Bang, SK1
Choi, KH1
Ryu, Y1
Galland, BC1
Gray, AR1
Penno, J1
Smith, C1
Lobb, C1
Taylor, RW1
Qiao, H1
Ye, X1
Bai, X1
He, J1
Li, T1
Zhang, J1
Zhang, W1
Xu, J1
Frozi, J1
de Carvalho, HW1
Ottoni, GL1
Cunha, RA1
Lara, DR1
Takemoto, H1
Takahashi, J1
Hyuga, S1
Odaguchi, H1
Uchiyama, N1
Maruyama, T1
Yamashita, T1
Hyuga, M1
Oshima, N1
Amakura, Y1
Hakamatsuka, T1
Goda, Y1
Hanawa, T1
Kobayashi, Y1
Kerpershoek, ML1
Antypa, N1
Van den Berg, JF1
Treur, JL1
Gibson, M1
Taylor, AE1
Rogers, PJ1
Munafò, MR1
Iversen, KL1
Arnesen, E1
Meltzer, HM1
Brantsæter, AL1
Kwon, S1
Yoon, M1
Lee, J1
Moon, KD1
Kim, D1
Kim, SB1
Cho, S1
Kromhout, MA2
Rius Ottenheim, N1
Giltay, E1
Numans, ME1
Achterberg, WP2
Bhatti, SK1
O'Keefe, JH1
Lavie, CJ1
Jongerling, J1
Ko, CH1
Koon, CM1
Yu, SL1
Lee, KY1
Lau, CB1
Chan, EH1
Wing, YK1
Fung, KP1
Leung, PC1
Salinero, JJ2
Lara, B2
Abian-Vicen, J2
Gonzalez-Millán, C2
Areces, F2
Gallo-Salazar, C2
Ruiz-Vicente, D2
Del Coso, J2
Gill, JD1
Biyani, CS1
Skarupke, C1
Schlack, R1
Lange, K1
Goerke, M1
Dueck, A1
Thome, J1
Szagun, B1
Cohrs, S1
Koivusilta, L1
Kuoppamäki, H1
Rimpelä, A1
Clark, I1
Landolt, HP2
Ramakrishnan, S1
Wesensten, NJ2
Kamimori, GH1
Moon, JE1
Balkin, TJ2
Reifman, J1
Watson, EJ1
Coates, AM1
Kohler, M1
Banks, S1
Paterson, LM3
Nutt, DJ3
Ivarsson, M3
Hutson, PH3
Wilson, SJ3
Gadinger, MC1
Fischer, JE1
Schneider, S1
Fischer, GC1
Frank, G1
Kromm, W1
Youngberg, MR1
Karpov, IO1
Begley, A1
Pollock, BG1
Buysse, DJ1
Ong, JC1
Park, M1
Wierzejska, R1
Lohsoonthorn, V2
Khidir, H1
Casillas, G1
Lertmaharit, S1
Tadesse, MG1
Pensuksan, WC1
Rattananupong, T1
Gelaye, B2
Williams, MA2
Wiwanitkit, V1
Ruiz-Vega, G1
Pérez-Ordaz, L1
Cortés-Galván, L1
Juárez-G, FM1
Bonnet, MH3
Arand, DL2
Stepanski, EJ1
Wyatt, JK1
SAUDAN, Y1
SCHPAK, VM1
Cheek, RE2
Shaver, JL2
Lentz, MJ2
Cooper, M1
Safran, M1
Eberhardt, M1
Linden, K1
Jormanainen, V1
Swigonski, NL1
Pietilä, K1
Sanchez-Ortuno, M1
Moore, N1
Taillard, J1
Valtat, C1
Leger, D1
Bioulac, B1
Philip, P1
Schulte, P1
Sanner, B1
Dinges, DF1
Roehrs, T2
Rogers, NL1
Abbott, RD1
Ross, GW1
White, LR1
Tanner, CM1
Masaki, KH1
Nelson, JS1
Curb, JD1
Petrovitch, H1
Salín-Pascual, RJ1
Valencia-Flores, M1
Campos, RM1
Castaño, A1
Shiromani, PJ1
Bonnet, M1
Omvik, S1
Pallesen, S1
Bjorvatn, B1
Thayer, J1
Nordhus, IH1
Drake, CL1
Jefferson, C1
Roth, T1
McCrae, CS1
Rowe, MA1
Dautovich, ND1
Lichstein, KL1
Durrence, HH1
Riedel, BW1
Bush, AJ1
Okuma, T2
Matsuoka, H1
Matsue, Y1
Toyomura, K1
Snyder, SH1
Sklar, P1
Edelstein, BA1
Keaton-Brasted, C1
Burg, MM1
Hicks, RA1
Kilcourse, J1
Sinnott, MA1
Levy, M1
Zylber-Katz, E1
Hiraga, H1
Ichijo, S1
Victor, BS1
Lubetsky, M1
Greden, JF1
Regestein, QR1
Reich, P1
Onen, SH1
Onen, F1
Bailly, D1
Parquet, P1
Curless, R1
French, JM1
James, OF1
Wynne, HA1
Tiffin, P1
Ashton, H1
Marsh, R1
Kamali, F1
Lee, TH1
Feikema, WJ1
Spierings, EL1
Hughes, JR1
Liguori, A1
Dominick, A1
MacLaughlin, M1
Suomela, T1
Henriksson, M1
Brezinová, V1
Oswald, I1
Loudon, J1
Lutz, EG1
Mellman, TA1
Uhde, TW1
Vollrath, M1
Wicki, W1
Angst, J1
Pawlicki, RE1
Heitkemper, T1
Shirlow, MJ1
Mathers, CD1
Walsh, JK1
Sugerman, JL1
Chambers, GW1
Forrest, WH1
Bellville, JW1
Brown, BW1
Silver, W1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Head-to-Head Comparison of the 2B-Alert Caffeine Optimization Algorithm Versus Standard Caffeine Dosing on Performance During Sleep Deprivation (2B-2)[NCT05588934]180 participants (Anticipated)Interventional2023-02-28Not yet recruiting
Effects of a Self-management Program for Temporomandibular Myalgia in Subjects With Fibromyalgia: a Single Arm Study[NCT05426655]40 participants (Anticipated)Interventional2022-06-16Recruiting
Effect of Physical Activity Program During Academic Stress on Adolescent Sleep[NCT04187885]56 participants (Anticipated)Interventional2020-09-03Not yet recruiting
A Photoplethysmography Sensor-based Personalized Feedback Intervention for Heavy-drinking Young Adults Targeting Heart Rate Variability, Resting Heart Rate, and Sleep[NCT05090995]60 participants (Actual)Interventional2022-02-23Active, not recruiting
Effects of Sleep Hygiene Education and Lavender Oil Inhalation on Sleep Quality, Fatigue, and Health-related Quality of Life in Adults With a Stoma: A Randomized Controlled Trial Protocol[NCT05573256]120 participants (Actual)Interventional2022-06-14Completed
The Effect of Lavender Aromatherapy on Sleep in Hospitalized Adult Patients[NCT04648215]108 participants (Actual)Interventional2021-02-22Terminated (stopped due to unavailable subjects)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for caffeine and Chronic Insomnia

ArticleYear
A Brewed Awakening: Neuropsychiatric Effects of Caffeine in Older Adults.
    Clinics in geriatric medicine, 2022, Volume: 38, Issue:1

    Topics: Aged; Alzheimer Disease; Caffeine; Humans; Parkinson Disease; Psychotropic Drugs; Sleep Initiation a

2022
The Impact of Dietary Factors on the Sleep of Athletically Trained Populations: A Systematic Review.
    Nutrients, 2022, Aug-10, Volume: 14, Issue:16

    Topics: Athletes; Athletic Performance; Caffeine; Carbohydrates; Humans; Sleep; Sleep Initiation and Mainten

2022
Genetics of caffeine and brain-related outcomes - a systematic review of observational studies and randomized trials.
    Nutrition reviews, 2023, Nov-10, Volume: 81, Issue:12

    Topics: Adult; Brain; Caffeine; Cytochrome P-450 CYP1A2; Genome-Wide Association Study; Humans; Randomized C

2023
A systematic review and meta-analysis of the association between young adults' sleep habits and substance use, with a focus on self-medication behaviours.
    Sleep medicine reviews, 2023, Volume: 70

    Topics: Caffeine; Circadian Rhythm; Ethanol; Humans; Nicotine; Sleep; Sleep Initiation and Maintenance Disor

2023
The effects of caffeinated products on sleep and functioning in the military population: A focused review.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 206

    Topics: Caffeine; Clinical Trials as Topic; Coffee; Cognition; Energy Drinks; Female; Humans; Male; Military

2021
Caffeine and neuropsychiatric symptoms in patients with dementia: A systematic review.
    Experimental gerontology, 2019, 07-15, Volume: 122

    Topics: Apathy; Caffeine; Dementia; Humans; Motor Skills; Nursing Homes; Randomized Controlled Trials as Top

2019
Coffee and tea: perks for health and longevity?
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:6

    Topics: Antioxidants; Anxiety; Blood Glucose; Blood Pressure; Caffeine; Calcium; Cardiovascular Diseases; Co

2013
Coffee, caffeine, and sleep: A systematic review of epidemiological studies and randomized controlled trials.
    Sleep medicine reviews, 2017, Volume: 31

    Topics: Age Factors; Caffeine; Coffee; Epidemiologic Studies; Humans; Randomized Controlled Trials as Topic;

2017
[Self-rated Caffeine Sensitivity: Implications for Personalized Sleep Medicine?].
    Praxis, 2016, May-11, Volume: 105, Issue:10

    Topics: Alleles; Caffeine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Genotype; Humans; P

2016
Chronic headaches and insomnia: working toward a biobehavioral model.
    Cephalalgia : an international journal of headache, 2012, Volume: 32, Issue:14

    Topics: Actigraphy; Adaptation, Psychological; Caffeine; Chronobiology Phenomena; Comorbidity; Headache Diso

2012
[Caffeine--common ingredient in a diet and its influence on human health].
    Roczniki Panstwowego Zakladu Higieny, 2012, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Brain; Caffeine; Cardiovascular Diseases; Central Nervous System Stimulants; Chil

2012
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
Use of sleep hygiene in the treatment of insomnia.
    Sleep medicine reviews, 2003, Volume: 7, Issue:3

    Topics: Body Temperature; Caffeine; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Environ

2003
The use of stimulants to modify performance during sleep loss: a review by the sleep deprivation and Stimulant Task Force of the American Academy of Sleep Medicine.
    Sleep, 2005, Volume: 28, Issue:9

    Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Humans; Methamphetamine; Modafini

2005
[Prevention and treatment of sleep disorders through regulation] of sleeping habits].
    Presse medicale (Paris, France : 1983), 1994, Mar-12, Volume: 23, Issue:10

    Topics: Caffeine; Circadian Rhythm; Disorders of Excessive Somnolence; Ethanol; Health Behavior; Humans; Nic

1994
[Headache and chronic sleep deprivation: an often missed relationship in children and also in adults].
    Nederlands tijdschrift voor geneeskunde, 1999, Sep-18, Volume: 143, Issue:38

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Caffeine; Central Nervous System Stimulants; Child; Ch

1999

Trials

8 trials available for caffeine and Chronic Insomnia

ArticleYear
The use of energy drinks in sport: perceived ergogenicity and side effects in male and female athletes.
    The British journal of nutrition, 2014, Nov-14, Volume: 112, Issue:9

    Topics: Adult; Anxiety; Athletes; Athletic Performance; Caffeine; Double-Blind Method; Energy Drinks; Exerci

2014
Acute consumption of a caffeinated energy drink enhances aspects of performance in sprint swimmers.
    The British journal of nutrition, 2015, Sep-28, Volume: 114, Issue:6

    Topics: Adolescent; Adult; Athletes; Athletic Performance; Caffeine; Double-Blind Method; Energy Drinks; Exe

2015
Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:5

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Electro

2009
A translational, caffeine-induced model of onset insomnia in rats and healthy volunteers.
    Psychopharmacology, 2007, Volume: 191, Issue:4

    Topics: Adult; Animals; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Disease Models, Ani

2007
Model insomnia by methylphenidate and caffeine and use in the evaluation of temazepam.
    Psychopharmacology, 1982, Volume: 76, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Caffeine; Drug Evaluation; Electroencephalography; Electrooculography; H

1982
Effect of smoking abstinence on the subjective effects of caffeine.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 1999, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Anxiety; Caffeine; Double-Blind Method; Drug Interactions; Female; Humans; Male;

1999
Caffeine use as a model of acute and chronic insomnia.
    Sleep, 1992, Volume: 15, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Arousal; Attention; Caffeine; Chronic Disease; Circadian Rhythm; D

1992
The interaction of caffeine with pentobarbital as a nighttime hypnotic.
    Anesthesiology, 1972, Volume: 36, Issue:1

    Topics: Caffeine; Coffee; Drug Interactions; Feeding Behavior; Female; Humans; Male; Middle Aged; Pentobarbi

1972

Other Studies

81 other studies available for caffeine and Chronic Insomnia

ArticleYear
Sleep Disorders and Future Diagnosis of Parkinsonism: A Prospective Study Using the Canadian Longitudinal Study on Aging.
    Journal of Parkinson's disease, 2022, Volume: 12, Issue:1

    Topics: Aged; Aging; Caffeine; Canada; Disorders of Excessive Somnolence; Humans; Longitudinal Studies; Male

2022
COVID-19 Lockdowns: A Worldwide Survey of Circadian Rhythms and Sleep Quality in 3911 Athletes from 49 Countries, with Data-Driven Recommendations.
    Sports medicine (Auckland, N.Z.), 2022, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Athletes; Caffeine; Circadian Rhythm; Communicable Disease Control; COVID-19; Cro

2022
GABA
    Molecules (Basel, Switzerland), 2021, Nov-24, Volume: 26, Issue:23

    Topics: Acids; Animals; Bicuculline; Caffeine; Cyclohexenes; Disease Models, Animal; Electroencephalography;

2021
Too Jittery to Sleep? Temporal Associations of Actigraphic Sleep and Caffeine in Adolescents.
    Nutrients, 2021, Dec-23, Volume: 14, Issue:1

    Topics: Actigraphy; Adolescent; Beverages; Caffeine; Feeding Behavior; Female; Humans; Longitudinal Studies;

2021
Who is the hardest to wake up from sleep? An investigation of self-reported sleep inertia using a latent profile analysis.
    Journal of sleep research, 2022, Volume: 31, Issue:5

    Topics: Caffeine; Humans; Self Report; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorde

2022
Caffeine Intake among Undergraduate Students: Sex Differences, Sources, Motivations, and Associations with Smoking Status and Self-Reported Sleep Quality.
    Nutrients, 2022, Apr-16, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Caffeine; Coffee; Cross-Sectional Studies; Female; Humans; Male; Motivation; Self

2022
The Positive Effects of
    International journal of environmental research and public health, 2022, 05-29, Volume: 19, Issue:11

    Topics: Animals; Caffeine; gamma-Aminobutyric Acid; Mice; Mice, Inbred ICR; Plant Extracts; Quality of Life;

2022
Prolonging effects of Valeriana fauriei root extract on pentobarbital-induced sleep in caffeine-induced insomnia model mice and the pharmacokinetics of its active ingredients under conditions of glycerol fatty acid ester as emulsifiers.
    Journal of ethnopharmacology, 2022, Nov-15, Volume: 298

    Topics: Animals; Caffeine; Esters; Fatty Acids; GABA Antagonists; Glycerol; Hypnotics and Sedatives; Mice; P

2022
Novel hypnotics of Japanese traditional herbal medicines to caffeine-induced insomnia in Drosophila by using Newly-developed automated sleep and rhythm analysis system (AutoCircaS).
    Gene, 2022, Dec-20, Volume: 846

    Topics: Animals; Caffeine; Circadian Rhythm; Drosophila; Drosophila melanogaster; Hypnotics and Sedatives; J

2022
Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice.
    Journal of ethnopharmacology, 2023, Feb-10, Volume: 302, Issue:Pt A

    Topics: Animals; Anxiety; Caffeine; Cholinergic Agents; Hypnotics and Sedatives; Lavandula; Mice; Oils, Vola

2023
Clinical study of "Jiaotai Pill" combined with head massage with 5-tone rhythm on insomnia patients of heart-kidney disharmony type.
    Medicine, 2023, Jan-06, Volume: 102, Issue:1

    Topics: Caffeine; Humans; Interleukin-8; Kidney; Massage; Sleep Initiation and Maintenance Disorders; Treatm

2023
Discrepancies Between Caregiver Reported Early Childhood Sleep Problems and Clinician Documentation and Referral.
    Academic pediatrics, 2023, Volume: 23, Issue:6

    Topics: Caffeine; Caregivers; Child; Child, Preschool; Female; Humans; Male; Referral and Consultation; Slee

2023
Using a frequentist and Bayesian approach to examine video game usage, substance use, and sleep among college students.
    Journal of sleep research, 2023, Volume: 32, Issue:4

    Topics: Bayes Theorem; Caffeine; Female; Humans; Male; Sleep Initiation and Maintenance Disorders; Students;

2023
Caffeine consumption and sleep in a submarine environment: An observational study.
    Journal of sleep research, 2023, Volume: 32, Issue:5

    Topics: Caffeine; Humans; Sleep; Sleep Deprivation; Sleep Initiation and Maintenance Disorders; Wakefulness

2023
COVID-19 Pandemic Responses among National Guard Service Members: Stressors, Coping Strategies, Sleep Difficultiesand Substance Use.
    International journal of environmental research and public health, 2023, 05-05, Volume: 20, Issue:9

    Topics: Adaptation, Psychological; Caffeine; COVID-19; Female; Humans; Male; Pandemics; Sleep Initiation and

2023
Retrospective Analysis of Risk Factors for Periodic Limb Movements in a Large Cohort of Insomnia and Chronic Fatigue Patients.
    Pharmacopsychiatry, 2020, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Belgium; Caffeine; Comorbidity; E

2020
The Impact of Genetic Variations in ADORA2A in the Association between Caffeine Consumption and Sleep.
    Genes, 2019, 12-06, Volume: 10, Issue:12

    Topics: Adolescent; Adult; Alleles; Caffeine; Female; Humans; Linkage Disequilibrium; Male; Middle Aged; Pol

2019
Dietary behaviors and poor sleep quality among young adult women: watch that sugary caffeine!
    Sleep health, 2020, Volume: 6, Issue:2

    Topics: Caffeine; Cross-Sectional Studies; Diet Surveys; Dietary Sugars; Feeding Behavior; Female; Humans; S

2020
The dynamic relationship between daily caffeine intake and sleep duration in middle-aged and older adults.
    Journal of sleep research, 2020, Volume: 29, Issue:6

    Topics: Actigraphy; Adult; Aged; Aged, 80 and over; Caffeine; Cross-Sectional Studies; Female; Humans; Male;

2020
Motivations Influencing Caffeine Consumption Behaviors among College Students in Korea: Associations with Sleep Quality.
    Nutrients, 2020, Mar-30, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Beverages; Caffeine; Eating; Female; Humans; Male; Motivation; Republic of Korea;

2020
The effect of caffeine abstinence on sleep among habitual caffeine users with poor sleep.
    Journal of sleep research, 2021, Volume: 30, Issue:1

    Topics: Adolescent; Caffeine; Female; Humans; Male; Sleep; Sleep Initiation and Maintenance Disorders

2021
Do sleep quality and caffeine consumption mediate the relationship between late chronotype and body mass index?
    Food & function, 2021, Jul-07, Volume: 12, Issue:13

    Topics: Adult; Beverages; Body Mass Index; Caffeine; Circadian Rhythm; Exercise; Female; Humans; Male; Obesi

2021
Acupuncture stimulation at HT7 as a non-pharmacological therapy for sleep disorder caused by caffeine administration in rats.
    Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2021, Volume: 39, Issue:6

    Topics: Acupuncture Points; Acupuncture Therapy; Animals; Caffeine; Humans; Male; Proto-Oncogene Proteins c-

2021
Gender differences in sleep hygiene practices and sleep quality in New Zealand adolescents aged 15 to 17 years.
    Sleep health, 2017, Volume: 3, Issue:2

    Topics: Adolescent; Body Mass Index; Caffeine; Cross-Sectional Studies; Female; Humans; Male; New Zealand; S

2017
Theacrine: A purine alkaloid from Camellia assamica var. kucha with a hypnotic property via the adenosine system.
    Neuroscience letters, 2017, 10-17, Volume: 659

    Topics: Adenosine; Alkaloids; Animals; Caffeine; Camellia; Drug Synergism; Hippocampus; Male; Mice; Pentobar

2017
Distinct sensitivity to caffeine-induced insomnia related to age.
    Journal of psychopharmacology (Oxford, England), 2018, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Brazil; Caffeine; Female; Humans; Male; Middle Aged; Sleep; Sleep Initiatio

2018
Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:2

    Topics: Alkaloids; Analgesics, Non-Narcotic; Animals; Animals, Outbred Strains; Anxiety; Arrhythmias, Cardia

2018
Evening use of caffeine moderates the relationship between caffeine consumption and subjective sleep quality in students.
    Journal of sleep research, 2018, Volume: 27, Issue:5

    Topics: Adult; Caffeine; Circadian Rhythm; Cross-Sectional Studies; Female; Humans; Male; Sleep Initiation a

2018
Investigating genetic correlations and causal effects between caffeine consumption and sleep behaviours.
    Journal of sleep research, 2018, Volume: 27, Issue:5

    Topics: Caffeine; Genome-Wide Association Study; Humans; Mendelian Randomization Analysis; Sleep; Sleep Init

2018
Children and adolescents need protection against energy drinks.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2018, 09-18, Volume: 138, Issue:14

    Topics: Adolescent; Caffeine; Child; Energy Drinks; Humans; Marketing; Norway; Sleep Initiation and Maintena

2018
A Standardized Phlorotannin Supplement Attenuates Caffeine-Induced Sleep Disruption in Mice.
    Nutrients, 2019, Mar-06, Volume: 11, Issue:3

    Topics: Animals; Caffeine; Electroencephalography; Electromyography; Follow-Up Studies; Hypnotics and Sedati

2019
Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study.
    The journal of nutrition, health & aging, 2014, Volume: 18, Issue:4

    Topics: Aged, 80 and over; Anxiety; Apathy; Behavioral Symptoms; Caffeine; Dementia; Female; Humans; Male; M

2014
Hypnotic effects of a novel anti-insomnia formula on Drosophila insomnia model.
    Chinese journal of integrative medicine, 2016, Volume: 22, Issue:5

    Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Disease Models, Animal; Drosophila melanoga

2016
Frequent urination causing sleepless nights in a 64-year-old man.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2015, Mar-17, Volume: 187, Issue:5

    Topics: Caffeine; Central Nervous System Stimulants; Coffee; Diuretics; Drinking Behavior; Humans; Male; Mid

2015
Insomnia complaints and substance use in German adolescents: did we underestimate the role of coffee consumption? Results of the KiGGS study.
    Journal of neural transmission (Vienna, Austria : 1996), 2017, Volume: 124, Issue:Suppl 1

    Topics: Adolescent; Caffeine; Central Nervous System Stimulants; Child; Coffee; Cross-Sectional Studies; Dat

2017
Energy drink consumption, health complaints and late bedtime among young adolescents.
    International journal of public health, 2016, Volume: 61, Issue:3

    Topics: Adolescent; Adolescent Behavior; Caffeine; Dose-Response Relationship, Drug; Energy Drinks; Fatigue;

2016
A Unified Model of Performance for Predicting the Effects of Sleep and Caffeine.
    Sleep, 2016, Oct-01, Volume: 39, Issue:10

    Topics: Adolescent; Adult; Caffeine; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; M

2016
Caffeine Consumption and Sleep Quality in Australian Adults.
    Nutrients, 2016, Aug-04, Volume: 8, Issue:8

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Caffeine; Carbonated Beverages; Coffee; Cross-Sectional

2016
Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:5

    Topics: Animals; Body Temperature; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Elec

2009
Female executives are particularly prone to the sleep-disturbing effect of isolated high-strain jobs: a cross-sectional study in German-speaking executives.
    Journal of sleep research, 2009, Volume: 18, Issue:2

    Topics: Adult; Alcohol Drinking; Austria; Caffeine; Career Mobility; Cross-Sectional Studies; Female; Gender

2009
Clinical and physiological correlates of caffeine and caffeine metabolites in primary insomnia.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2011, Apr-15, Volume: 7, Issue:2

    Topics: Adult; Caffeine; Chromatography, High Pressure Liquid; Electroencephalography; Female; Humans; Male;

2011
Sleep quality and sleep patterns in relation to consumption of energy drinks, caffeinated beverages, and other stimulants among Thai college students.
    Sleep & breathing = Schlaf & Atmung, 2013, Volume: 17, Issue:3

    Topics: Adolescent; Alcoholic Beverages; Beverages; Caffeine; Central Nervous System Stimulants; Cross-Secti

2013
Sleep and beverage drinking among Thai college students.
    Sleep & breathing = Schlaf & Atmung, 2013, Volume: 17, Issue:3

    Topics: Beverages; Caffeine; Central Nervous System Stimulants; Energy Drinks; Female; Humans; Male; Sleep;

2013
Author response to: Sleep and beverage drinking among Thai college students.
    Sleep & breathing = Schlaf & Atmung, 2013, Volume: 17, Issue:3

    Topics: Beverages; Caffeine; Central Nervous System Stimulants; Energy Drinks; Female; Humans; Male; Sleep;

2013
A kinetic approach to caffeine--Coffea cruda interaction.
    Homeopathy : the journal of the Faculty of Homeopathy, 2003, Volume: 92, Issue:1

    Topics: Animals; Caffeine; Central Nervous System Stimulants; Coffea; Drug Interactions; Electroencephalogra

2003
Insomnia, metabolic rate and sleep restoration.
    Journal of internal medicine, 2003, Volume: 254, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Arousal; Basal Metabolism; Caffeine; Central Nervous System

2003
[Treatment of insomnia in asthmatics with hypnasmine].
    Praxis, 1960, Dec-29, Volume: 49

    Topics: Asthma; Barbiturates; Caffeine; Humans; Sleep Initiation and Maintenance Disorders; Theophylline

1960
[Treatment of insomnia in borderline cases with individual doses of caffeine and bromide].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1960, Volume: 12

    Topics: Bromides; Caffeine; Humans; Sleep Initiation and Maintenance Disorders

1960
Lifestyle practices and nocturnal sleep in midlife women with and without insomnia.
    Biological research for nursing, 2004, Volume: 6, Issue:1

    Topics: Adult; Age Factors; Alcohol Drinking; Attitude to Health; Caffeine; Case-Control Studies; Exercise;

2004
Variations in sleep hygiene practices of women with and without insomnia.
    Research in nursing & health, 2004, Volume: 27, Issue:4

    Topics: Adult; Alcohol Drinking; Caffeine; Case-Control Studies; Chronic Disease; Educational Status; Exerci

2004
Caffeine consumption among adults on benzodiazepine therapy: United States 1988-1994.
    Psychological reports, 2004, Volume: 95, Issue:1

    Topics: Aged; Anxiety Disorders; Arousal; Benzodiazepines; Caffeine; Dose-Response Relationship, Drug; Drug

2004
Self-medication among Finnish young men in the beginning of common military service.
    Pharmacoepidemiology and drug safety, 2005, Volume: 14, Issue:3

    Topics: Adult; Anxiety; Caffeine; Central Nervous System Stimulants; Common Cold; Cross-Sectional Studies; E

2005
Sleep duration and caffeine consumption in a French middle-aged working population.
    Sleep medicine, 2005, Volume: 6, Issue:3

    Topics: Beverages; Caffeine; Central Nervous System Stimulants; Cohort Studies; Disorders of Excessive Somno

2005
[Falling asleep disorders after taking coffee?].
    Deutsche medizinische Wochenschrift (1946), 2005, May-20, Volume: 130, Issue:20

    Topics: Caffeine; Central Nervous System Stimulants; Coffee; Electroencephalography; Humans; Sleep; Sleep In

2005
Excessive daytime sleepiness and subsequent development of Parkinson disease.
    Neurology, 2005, Nov-08, Volume: 65, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Brain; Caffeine; Causality; Cognition Disorders; Cohort Studies; Com

2005
Caffeine challenge in insomniac patients after total sleep deprivation.
    Sleep medicine, 2006, Volume: 7, Issue:2

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Delta Rhythm; Diagnostic and Statistical Manual

2006
Etiology of insomnia.
    Sleep medicine, 2006, Volume: 7, Issue:7

    Topics: Age Factors; Caffeine; Chronic Disease; Humans; Risk Factors; Sleep Initiation and Maintenance Disor

2006
Night-time thoughts in high and low worriers: reaction to caffeine-induced sleeplessness.
    Behaviour research and therapy, 2007, Volume: 45, Issue:4

    Topics: Adolescent; Adult; Anxiety; Caffeine; Female; Humans; Psychometrics; Sleep Initiation and Maintenanc

2007
Stress-related sleep disturbance and polysomnographic response to caffeine.
    Sleep medicine, 2006, Volume: 7, Issue:7

    Topics: Adult; Arousal; Caffeine; Female; Humans; Individuality; Male; Middle Aged; Polysomnography; Referen

2006
Sleep hygiene practices in two community dwelling samples of older adults.
    Sleep, 2006, Volume: 29, Issue:12

    Topics: Aged; Aged, 80 and over; Alcohol Drinking; Anxiety; Caffeine; Central Nervous System Stimulants; Dem

2006
Behavioral and molecular actions of caffeine: focus on adenosine.
    Journal of psychiatric research, 1984, Volume: 18, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anxiety Disorders; Behavior; Caffeine; Child; Cycli

1984
Effects of caffeine withdrawal on nocturnal enuresis, insomnia, and behavior restraints.
    Journal of consulting and clinical psychology, 1984, Volume: 52, Issue:5

    Topics: Caffeine; Dangerous Behavior; Enuresis; Humans; Inpatients; Restraint, Physical; Sleep Initiation an

1984
Type A-B behavior and caffeine use in college students.
    Psychological reports, 1983, Volume: 52, Issue:1

    Topics: Caffeine; Coronary Disease; Humans; Personality; Sleep Initiation and Maintenance Disorders

1983
Caffeine metabolism and coffee-attributed sleep disturbances.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:6

    Topics: Adult; Caffeine; Coffee; Female; Humans; Kinetics; Male; Middle Aged; Sleep Initiation and Maintenan

1983
Long-term monitoring during sleep--a high-speed automatic processing system for human all-night sleep scoring and statistical data analysis.
    Electroencephalography and clinical neurophysiology. Supplement, 1982, Volume: 36

    Topics: Autoanalysis; Caffeine; Electroencephalography; Electromyography; Humans; Minicomputers; Monitoring,

1982
Somatic manifestations of caffeinism.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:5

    Topics: Adult; Arrhythmias, Cardiac; Caffeine; Central Nervous System Diseases; Diarrhea; Diuresis; Dose-Res

1981
A sleep clinic within a general hospital psychiatry service.
    General hospital psychiatry, 1980, Volume: 2, Issue:2

    Topics: Adult; Antidepressive Agents; Arousal; Caffeine; Depression; Female; Hospitals, General; Humans; Mal

1980
Is caffeine a factor in subjective insomnia of elderly people?
    Age and ageing, 1993, Volume: 22, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Caffeine; Coffee; Dose-Response Relationship, Drug; Female; Humans;

1993
Pharmacokinetic and pharmacodynamic responses to caffeine in poor and normal sleepers.
    Psychopharmacology, 1995, Volume: 121, Issue:4

    Topics: Adult; Caffeine; Female; Heart Rate; Humans; Male; Psychomotor Performance; Sleep; Sleep Initiation

1995
Puzzling through a case. The sleepless professor.
    Harvard health letter, 1999, Volume: 24, Issue:11

    Topics: Age Factors; Aged; Anxiety; Caffeine; Central Nervous System Stimulants; Exercise; Humans; Male; Sle

1999
[Headache and chronic sleep deprivation: an often missed relationship in children and also in adults].
    Nederlands tijdschrift voor geneeskunde, 1999, Dec-11, Volume: 143, Issue:50

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Child; Fatigue; Female; Headache; Humans; Male;

1999
[Persistent insomnia in a depressed athlete].
    Duodecim; laaketieteellinen aikakauskirja, 2001, Volume: 117, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Caffeine; Central Nervous System

2001
Two types of insomnia: too much waking or not enough sleep.
    The British journal of psychiatry : the journal of mental science, 1975, Volume: 126

    Topics: Age Factors; Caffeine; Electroencephalography; Eye Movements; Female; Humans; Hypnotics and Sedative

1975
Restless legs, anxiety and caffeinism.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Anxiety; Arousal; Caffeine; Coffee; Depression; Female; Humans; Male; Muscle Cont

1978
Sleep panic attacks: new clinical findings and theoretical implications.
    The American journal of psychiatry, 1989, Volume: 146, Issue:9

    Topics: Adult; Anxiety Disorders; Caffeine; Fear; Female; Humans; Male; Middle Aged; Panic; Sleep Initiation

1989
The Zurich study. VIII. Insomnia: association with depression, anxiety, somatic syndromes, and course of insomnia.
    European archives of psychiatry and neurological sciences, 1989, Volume: 239, Issue:2

    Topics: Adult; Alcohol Drinking; Anxiety Disorders; Caffeine; Cohort Studies; Conflict, Psychological; Depre

1989
Drugs for poor sleepers?
    British medical journal (Clinical research ed.), 1986, Apr-05, Volume: 292, Issue:6525

    Topics: Adult; Benzodiazepines; Caffeine; Humans; Sleep; Sleep Initiation and Maintenance Disorders

1986
Behavioral management of insomnia.
    Journal of psychosocial nursing and mental health services, 1985, Volume: 23, Issue:7

    Topics: Animals; Behavior Therapy; Caffeine; Circadian Rhythm; Conditioning, Classical; Humans; Hypnotics an

1985
A study of caffeine consumption and symptoms; indigestion, palpitations, tremor, headache and insomnia.
    International journal of epidemiology, 1985, Volume: 14, Issue:2

    Topics: Adult; Aged; Alcohol Drinking; Australia; Caffeine; Coffee; Cross-Sectional Studies; Digestion; Dose

1985
Evaluation of insomnia.
    American family physician, 1986, Volume: 33, Issue:4

    Topics: Adolescent; Benzodiazepines; Caffeine; Chronic Disease; Ethanol; Humans; Muscle Contraction; Psychop

1986
Insomnia, tachycardia, and cola drinks.
    Pediatrics, 1971, Volume: 47, Issue:3

    Topics: Beverages; Caffeine; Child; Humans; Sleep Initiation and Maintenance Disorders; Tachycardia

1971