caffeine has been researched along with Cell Transformation, Neoplastic in 40 studies
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After due ethical approval, 30 animals were treated with 40mg/kg single dose of 7,12-dimethylbenzene anthracene (DMBA) as a model for DNA damage and induction of carcinogenesis." | 4.31 | P53 Gene Expression and Nitric Oxide Levels after Artemisinin-Caffeine Treatment in Breast, Lungs and Liver of DMBA-Induced Tumorigenesis. ( Adelani, BI; Awani, OU; Dokunmu, TM; Enoma, DO; Imaga, NA; Opara, SC, 2023) |
| "Post-treatment with caffeine greatly diminishes the yields by 4NQO of mutants in E." | 2.36 | A test for mutation theory of cancer: carcinogenesis by misrepair of DNA damaged by 4-nitroquinoline 1-oxide. ( Kondo, S, 1977) |
| "Caffeine-SB was more active than an equimolar amount of caffeine in exerting a sunscreen effect." | 1.34 | Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 mice. ( Conney, AH; Lin, Y; Lou, YR; Lu, YP; Peng, QY; Shih, WJ; Xie, JG; Zhou, S, 2007) |
| "When caffeine was present for 48 hours immediately following UV irradiation, alkaline sucrose gradient sedimentation of DNA showed that postreplication repair was inhibited." | 1.26 | Dissociated occurrence of single-gene mutation and oncogenic transformation in C3H 10T1/2 cells exposed to ultraviolet light and caffeine. ( Chan, GL; Little, JB, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (15.00) | 29.6817 |
| 2010's | 1 (2.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Dokunmu, TM | 1 |
| Opara, SC | 1 |
| Imaga, NA | 1 |
| Awani, OU | 1 |
| Enoma, DO | 1 |
| Adelani, BI | 1 |
| Franco, R | 1 |
| Takacova, S | 1 |
| Slany, R | 1 |
| Bartkova, J | 1 |
| Stranecky, V | 1 |
| Dolezel, P | 1 |
| Luzna, P | 1 |
| Bartek, J | 1 |
| Divoky, V | 1 |
| Nomura, M | 2 |
| Ichimatsu, D | 1 |
| Moritani, S | 1 |
| Koyama, I | 1 |
| Dong, Z | 2 |
| Yokogawa, K | 1 |
| Miyamoto, K | 2 |
| Camouse, MM | 1 |
| Hanneman, KK | 1 |
| Conrad, EP | 1 |
| Baron, ED | 1 |
| Lu, YP | 1 |
| Lou, YR | 1 |
| Xie, JG | 1 |
| Peng, QY | 1 |
| Zhou, S | 1 |
| Lin, Y | 1 |
| Shih, WJ | 1 |
| Conney, AH | 2 |
| Rogozin, EA | 1 |
| Lee, KW | 1 |
| Kang, NJ | 1 |
| Yu, H | 1 |
| Bode, AM | 1 |
| Kuroki, T | 1 |
| Clegg, JC | 1 |
| Glatt, HR | 1 |
| Oesch, F | 1 |
| Parshad, R | 3 |
| Gantt, R | 1 |
| Sanford, KK | 3 |
| Jones, GM | 3 |
| Tarone, RE | 3 |
| Pardee, AB | 2 |
| Cherington, PV | 1 |
| Medrano, EE | 1 |
| DiPaolo, JA | 6 |
| Evans, CH | 1 |
| Popescu, NC | 1 |
| Doniger, JN | 1 |
| Chan, GL | 1 |
| Little, JB | 2 |
| Doniger, J | 1 |
| Mironescu, SG | 1 |
| Epstein, SM | 1 |
| Hoffman, HA | 1 |
| Grier, AH | 1 |
| Dolnikov, A | 1 |
| Millington, M | 1 |
| Sun, LQ | 1 |
| Symonds, G | 1 |
| Ide, T | 2 |
| Anzai, K | 2 |
| Andoh, T | 2 |
| James, LJ | 1 |
| Zamansky, GB | 1 |
| Kleinman, LF | 1 |
| Black, PH | 2 |
| Kaplan, JC | 1 |
| Morris, AG | 1 |
| Lavialle, C | 1 |
| Suarez, HG | 1 |
| Stevenet, J | 1 |
| Estrade, S | 1 |
| Cassingena, R | 1 |
| Kondo, S | 1 |
| Maziére, C | 1 |
| Maziére, JC | 1 |
| Bowden, GT | 1 |
| Giesselbach, B | 1 |
| Fusenig, NE | 1 |
| Donovan, PJ | 2 |
| Kakunaga, T | 1 |
| Casto, BC | 1 |
| Pieczynski, WJ | 1 |
| Janosko, N | 1 |
| Rivedal, E | 1 |
| Sanner, T | 1 |
| Cleaver, JE | 1 |
| Banda, MJ | 1 |
| Troll, W | 1 |
| Borek, C | 1 |
| Jan, KY | 1 |
| Huang, RY | 1 |
| Lee, TC | 1 |
| Rothschild, H | 1 |
| Kreider, JW | 1 |
| Rosenthal, M | 1 |
| Lengle, N | 1 |
| Seemayer, NH | 2 |
| Defendi, V | 2 |
| Yoshikura, H | 1 |
| Ledinko, N | 1 |
| Evans, M | 1 |
| Paschke, M | 1 |
| Schwanitz, F | 1 |
4 reviews available for caffeine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
[Coffee and cancer].
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anticarcinogenic Agents; Caffeine; Cell Trans | 2008 |
Protective effects of tea polyphenols and caffeine.
Topics: Antioxidants; Apoptosis; Caffeine; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevent | 2005 |
In vitro carcinogenesis by 4-nitroquinoline 1-oxide and related compounds.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; Carcinogens; Cell Cycle; Cell Transformation, Neoplasti | 1981 |
A test for mutation theory of cancer: carcinogenesis by misrepair of DNA damaged by 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; Cell Transformation, Neoplastic; DNA; DNA Repair; DNA, | 1977 |
36 other studies available for caffeine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
P53 Gene Expression and Nitric Oxide Levels after Artemisinin-Caffeine Treatment in Breast, Lungs and Liver of DMBA-Induced Tumorigenesis.
Topics: Animals; Anthracenes; Artemisinins; Caffeine; Carcinogenesis; Cell Transformation, Neoplastic; Gene | 2023 |
DNA damage response and inflammatory signaling limit the MLL-ENL-induced leukemogenesis in vivo.
Topics: Animals; Caffeine; Cell Cycle Checkpoints; Cell Proliferation; Cell Transformation, Neoplastic; DNA | 2012 |
Inhibition of epidermal growth factor-induced cell transformation and Akt activation by caffeine.
Topics: Animals; Caffeine; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Enzyme Activation; Epider | 2005 |
Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 mice.
Topics: Administration, Topical; Animals; Antimutagenic Agents; Apoptosis; Benzoates; Caffeine; Cell Transfo | 2007 |
Inhibitory effects of caffeine analogues on neoplastic transformation: structure-activity relationship.
Topics: Animals; Antineoplastic Agents; Caffeine; Cell Line; Cell Transformation, Neoplastic; Enzyme Activat | 2008 |
Coordinate mutation and transformation of mouse fibroblasts: induction by nitroquinoline oxide and modulation by caffeine.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; Cell Transformation, Neoplastic; Cells, Cultured; Drug | 1981 |
Repair of chromosome damage induced by X-irradiation during G2 phase in a line of normal human fibroblasts and its malignant derivative.
Topics: 4-Nitroquinoline-1-oxide; Caffeine; Catalase; Cell Line; Cell Transformation, Neoplastic; Chromosome | 1982 |
Neoplastic transformation of human cells in culture associated with deficient repair of light-induced chromosomal DNA damage.
Topics: Caffeine; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Chromatids; DNA Repair; Huma | 1982 |
On deciding which factors regulate cell growth.
Topics: Animals; Caffeine; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Trans | 1981 |
Regulation of mammalian cell transformation.
Topics: Animals; Antipain; Caffeine; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcin | 1982 |
Dissociated occurrence of single-gene mutation and oncogenic transformation in C3H 10T1/2 cells exposed to ultraviolet light and caffeine.
Topics: Animals; Caffeine; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Emb | 1982 |
Modulation of in vitro transformation and the early and late modes of DNA replication of uv-irradiated Syrian hamster cells by caffeine.
Topics: Animals; Caffeine; Cell Line; Cell Transformation, Neoplastic; Cricetinae; DNA; DNA Replication; Emb | 1981 |
Relationship between morphological transformation and [3H]thymidine incorporation stimulated by a chemical carcinogen in postconfluent cultures of hamster embryo cells.
Topics: Animals; Autoradiography; Caffeine; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cel | 1980 |
Susceptibility to fluorescent light-induced chromatid breaks associated with DNA repair deficiency and malignant transformation in culture.
Topics: Animals; Caffeine; Catalase; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Chromatids; Chr | 1980 |
Induced p21WAF1 expression acts to reverse myc myelomonocytic cell transformation.
Topics: Animals; Apoptosis; Blotting, Northern; Caffeine; Carcinogens; Cell Division; Cell Line; Cell Transf | 2000 |
Enhancement of SV40 transformation by treatment of C3H2K cells with UV light and caffeine. I. Combined effect of UV light and caffeine.
Topics: Animals; Bucladesine; Caffeine; Cell Line; Cell Transformation, Neoplastic; Cobalt Radioisotopes; Do | 1975 |
Selective killing of transformed baby hamster kidney (BHK) cells.
Topics: Antibiotics, Antineoplastic; Caffeine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cy | 1975 |
Enhancement of SV40 transformation by treatment of C3H2K cells with UV light and caffeine. II. The effects of multiplicity of infection, cell phase, and time with caffeine.
Topics: Animals; Caffeine; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Repair; DNA Replic | 1976 |
The effect of caffeine on the ultraviolet light induction of SV40 virus from transformed hamster cells.
Topics: Caffeine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Dru | 1976 |
Simian virus 40-Chinese hamster kidney cell interaction. III. Characteristics of chemical induction in a clone of virogenic transformed cells.
Topics: Animals; Bucladesine; Caffeine; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; | 1977 |
[Stimulation of the synthesis and non-competitive inhibition of alkaline phosphatase by theophylline in normal hamster fibroblasts and absence of response in transformed fibroblasts].
Topics: Alkaline Phosphatase; Animals; Caffeine; Cell Transformation, Neoplastic; Cells, Cultured; Cricetina | 1977 |
Postreplication repair of DNA in ultraviolet light-irradiated normal and malignancy transformed mouse epidermal cell cultures.
Topics: Animals; Caffeine; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Repair; DNA Replicatio | 1978 |
Transformation frequency of Syrian golden hamster cells and its modulation by ultraviolet irradiation.
Topics: Acetoxyacetylaminofluorene; Animals; Caffeine; Cell Transformation, Neoplastic; Cells, Cultured; Coc | 1978 |
Caffeine inhibits cell transformation by 4-nitroquinoline-1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Caffeine; Cell Line; Cell Transformation, Neoplastic; DNA Repair; Dose-Res | 1975 |
Significance of treatment interval and DNA repair in the enhancement of viral transformation by chemical carcinogens and mutagens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetoxyacetylaminofluorene; Adenoviridae; Aflatoxins; Benzopyrenes | 1976 |
Caffeine and other phosphodiesterase inhibitors are potent inhibitors of the promotional effect of TPA on morphological transformation of hamster embryo cells.
Topics: Adenylyl Cyclases; Animals; Bucladesine; Caffeine; Cell Communication; Cell Transformation, Neoplast | 1985 |
Some protease inhibitors are also inhibitors of poly(ADP-ribose) polymerase.
Topics: Antipain; Benzamides; Caffeine; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Lymphocyte | 1986 |
Different modes of action of sodium arsenite, 3-aminobenzamide, and caffeine on the enhancement of ethyl methanesulfonate clastogenicity.
Topics: Animals; Arsenic; Arsenites; Benzamides; Caffeine; Cell Cycle; Cell Line; Cell Transformation, Neopl | 1986 |
Analysis of SV40-induced transformation of hamster kidney tissue in vitro. VII. Induction of SV40 virus from transformed hamster cell clones by various agents.
Topics: Acridines; Animals; Bromodeoxyuridine; Caffeine; Cell Line; Cell Transformation, Neoplastic; Chromos | 1970 |
Cyclic adenosine 3',5'-monophosphate in the control of melanoma cell replication and differentiation.
Topics: Caffeine; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cyc | 1973 |
Analysis of minimal functions of simian virus 40. 3. Evidence for "host cell repair" of oncogenicity and infectivity of UV-irradiated simian virus 40.
Topics: Animals; Autoradiography; Caffeine; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cri | 1974 |
Caffeine inhibits induction of endogenous C-type virus.
Topics: Animals; Caffeine; Cell Transformation, Neoplastic; Cells, Cultured; Deoxyuridine; Dose-Response Rel | 1974 |
Analysis of minimal functions of simian virus 40. IV. Oncogenic transformation of syrian hamster kidney cells in vitro by beta-propiolactone inactivated sv40.
Topics: Animals; Caffeine; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; DNA, | 1974 |
Caffeine enhancement of chemical carcinogen-induced transformation of cultured Syrian hamster cells.
Topics: Acetamides; Animals; Benzopyrenes; Caffeine; Carcinogens; Cell Division; Cell Transformation, Neopla | 1974 |
Enhancement of adenovirus transformation of hamster cells by N-methyl-N'-nitro-N-nitrosoguanidine, caffeine, and hydroxylamine.
Topics: Adenoviridae; Animals; Caffeine; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cr | 1973 |
[Pretesting of drugs using lower and higher plants. II. Effect of phenazetin and various substances frequently combined with it, on the shape and growth of Micrasterias americana].
Topics: Antineoplastic Agents; Biological Assay; Caffeine; Cell Division; Cell Transformation, Neoplastic; D | 1971 |