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caffeine and Cardiac Hypertrophy

caffeine has been researched along with Cardiac Hypertrophy in 28 studies

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"Intermittent exposure to CPF induced cardiac hypertrophy, increasing cardiomyocyte diameter and collagen content."5.72Intermittent exposure to chlorpyrifos results in cardiac hypertrophy and oxidative stress in rats. ( Aitken, AV; Batista, TJ; Beijamini, V; Bissoli, NS; Coitinho, JB; de Sousa, GJ; Gonçalves, RCR; Hott, SC; Minassa, VS; Paton, JFR; Sampaio, KN, 2022)
"Compensated cardiac hypertrophy was induced by abdominal aortic constriction for 5 wk followed by administration of ramipril (50 microg x kg(-1) x day(-1)) or vehicle for 4 wk."5.31Low-dose ramipril treatment improves relaxation and calcium cycling after established cardiac hypertrophy. ( Boateng, SY; Boheler, KR; Koban, MU; MacLeod, KT; Naqvi, RU; Yacoub, MH, 2001)
"This study aimed to quantify the effect of cardiac hypertrophy induced with isoprenaline and caffeine on reflex regulation of renal sympathetic nerve activity by the arterial and cardiopulmonary baroreceptors."3.74Impact of cardiac hypertrophy on arterial and cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetized rats. ( Aherne, CM; Buckley, MM; Flanagan, ET; Johns, EJ; Lainis, F; Sattar, M, 2008)
"Intermittent exposure to CPF induced cardiac hypertrophy, increasing cardiomyocyte diameter and collagen content."1.72Intermittent exposure to chlorpyrifos results in cardiac hypertrophy and oxidative stress in rats. ( Aitken, AV; Batista, TJ; Beijamini, V; Bissoli, NS; Coitinho, JB; de Sousa, GJ; Gonçalves, RCR; Hott, SC; Minassa, VS; Paton, JFR; Sampaio, KN, 2022)
"Compensated cardiac hypertrophy was induced by abdominal aortic constriction for 5 wk followed by administration of ramipril (50 microg x kg(-1) x day(-1)) or vehicle for 4 wk."1.31Low-dose ramipril treatment improves relaxation and calcium cycling after established cardiac hypertrophy. ( Boateng, SY; Boheler, KR; Koban, MU; MacLeod, KT; Naqvi, RU; Yacoub, MH, 2001)
"Thus, in spite of the modest cardiac hypertrophy, the overexpressed LCCs form functional coupling with RyRs, preserving both orthograde and retrograde Ca(2+) signaling between LCCs and RyRs."1.31Ca(2+) signaling in cardiac myocytes overexpressing the alpha(1) subunit of L-type Ca(2+) channel. ( Cheng, H; Guia, A; Josephson, IR; Lakatta, EG; Muth, JN; Rubio, M; Schwartz, A; Song, LS; Wang, SQ; Xiao, RP, 2002)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's8 (28.57)18.2507
2000's11 (39.29)29.6817
2010's5 (17.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Minassa, VS1
Aitken, AV1
Hott, SC1
de Sousa, GJ1
Batista, TJ1
Gonçalves, RCR1
Coitinho, JB1
Paton, JFR1
Beijamini, V1
Bissoli, NS1
Sampaio, KN1
Zhong, X1
Vallmitjana, A1
Sun, B1
Xiao, Z1
Guo, W1
Wei, J1
Ni, M1
Chen, Y1
O'Brien, ER1
Gillis, AM1
Hoshijima, M1
Takeshima, H1
Hove-Madsen, L1
Benitez, R1
Belke, D1
Wayne Chen, SR1
Landstrom, AP1
Kellen, CA1
Dixit, SS1
van Oort, RJ1
Garbino, A1
Weisleder, N1
Ma, J1
Wehrens, XH1
Ackerman, MJ1
Hulot, JS1
Fauconnier, J1
Ramanujam, D1
Chaanine, A1
Aubart, F1
Sassi, Y1
Merkle, S1
Cazorla, O1
Ouillé, A1
Dupuis, M1
Hadri, L1
Jeong, D1
Mühlstedt, S1
Schmitt, J1
Braun, A1
Bénard, L1
Saliba, Y1
Laggerbauer, B1
Nieswandt, B1
Lacampagne, A1
Hajjar, RJ2
Lompré, AM1
Engelhardt, S1
Buckley, MM2
Johns, EJ2
Ruiz-Hurtado, G1
Domínguez-Rodríguez, A1
Pereira, L1
Fernández-Velasco, M1
Cassan, C1
Lezoualc'h, F1
Benitah, JP1
Gómez, AM1
Kirchhefer, U2
Baba, HA2
Kobayashi, YM2
Jones, LR3
Schmitz, W2
Neumann, J2
Maier, LS1
Zhang, T1
Chen, L1
DeSantiago, J1
Brown, JH1
Bers, DM2
HEIMANN, W1
WILBRANDT, W1
Ng, GA1
Song, LJ1
Wang, GL1
Liu, J1
Qiu, QY1
Ou, JH1
Guan, YY1
Flanagan, ET1
Aherne, CM1
Lainis, F1
Sattar, M1
Aronson, RS1
Nordin, C1
Naqvi, RU2
Macleod, KT2
Tomita, F1
Bassett, AL2
Myerburg, RJ2
Kimura, S2
Suzuki, YJ1
Wang, W1
Ramesh, V1
Franzini-Armstrong, C1
Cleemann, L1
Morad, M1
Pogwizd, SM1
Qi, M1
Yuan, W1
Samarel, AM1
Linck, B1
Bokník, P1
Huke, S1
Knapp, J1
Lüss, H1
Müller, FU1
Tanriseven, Z1
Vahlensieck, U1
Philipson, KD1
Boateng, SY1
Koban, MU1
Yacoub, MH1
Boheler, KR1
Meyer, TE1
Chung, ES1
Perlini, S1
Norton, GR1
Woodiwiss, AJ1
Lorbar, M1
Fenton, RA1
Dobson, JG1
Kline, R1
Jiang, T1
Xu, X1
Rybin, VO1
Steinberg, SF1
Karvats'kiĭ, IM1
Lahodych, TS1
Shevchuk, VH1
Song, LS1
Guia, A1
Muth, JN1
Rubio, M1
Wang, SQ1
Xiao, RP1
Josephson, IR1
Lakatta, EG1
Schwartz, A1
Cheng, H1
Rooke, GA1
Su, JY1
Furukawa, T1
Furukawa, N1
Baudet, S1
Ventura-Clapier, R1
Gwathmey, JK1
Thollon, C1
Kreher, P1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry[NCT05158751]100 participants (Anticipated)Observational2023-01-31Not yet recruiting
Role of a Novel Implantable Loop Recorder in the Management of Premature Ventricular Contractions[NCT06060548]50 participants (Anticipated)Observational2022-04-20Recruiting
Risk Stratifications for Patients Come With Palpitations in Assiut and Suez Canal University Hospitals[NCT06103305]208 participants (Anticipated)Observational2023-10-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for caffeine and Cardiac Hypertrophy

ArticleYear
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006
Treating patients with ventricular ectopic beats.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:11

    Topics: Caffeine; Cardiomegaly; Electrocardiography; Exercise; Humans; Hypertension; Prognosis; Tachycardia,

2006

Other Studies

27 other studies available for caffeine and Cardiac Hypertrophy

ArticleYear
Intermittent exposure to chlorpyrifos results in cardiac hypertrophy and oxidative stress in rats.
    Toxicology, 2022, Volume: 482

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Caffeine; Cardiomegaly; Chlorpyrifos; Humans;

2022
Reduced expression of cardiac ryanodine receptor protects against stress-induced ventricular tachyarrhythmia, but increases the susceptibility to cardiac alternans.
    The Biochemical journal, 2018, 01-05, Volume: 475, Issue:1

    Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Signaling; Cardiomegaly; Death, Sudden, Cardi

2018
Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling.
    Circulation. Heart failure, 2011, Volume: 4, Issue:2

    Topics: Animals; Caffeine; Calcium Channels, L-Type; Calcium Signaling; Cardiomegaly; Cardiomyopathy, Hypert

2011
Critical role for stromal interaction molecule 1 in cardiac hypertrophy.
    Circulation, 2011, Aug-16, Volume: 124, Issue:7

    Topics: Adenoviridae; Age Factors; Animals; Animals, Newborn; Caffeine; Calcium; Calcium Channels; Calcium S

2011
Impact of L-NAME on the cardiopulmonary reflex in cardiac hypertrophy.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:5

    Topics: Animals; Baroreflex; Blood Pressure; Blood Volume; Caffeine; Cardiomegaly; Disease Models, Animal; D

2011
Sustained Epac activation induces calmodulin dependent positive inotropic effect in adult cardiomyocytes.
    Journal of molecular and cellular cardiology, 2012, Volume: 53, Issue:5

    Topics: Animals; Caffeine; Calcium Channels, L-Type; Calcium Signaling; Calmodulin; Cardiomegaly; Cells, Cul

2012
Altered function in atrium of transgenic mice overexpressing triadin 1.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Age Factors; Animals; Atrial Function; Caffeine; Calcium; Calcium-Binding Proteins; Calcium-Transpor

2002
Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release.
    Circulation research, 2003, May-02, Volume: 92, Issue:8

    Topics: Animals; Benzylamines; Blotting, Western; Caffeine; Calcium; Calcium Channels; Calcium-Binding Prote

2003
[Studies on coronary-dilatating effects on Langendorff's preparation and its interpretation on the basis of competitive antagonism].
    Helvetica physiologica et pharmacologica acta, 1954, Volume: 12, Issue:3

    Topics: Caffeine; Cardiomegaly; Heart; Humans; Khellin; Papaverine; Theophylline

1954
Cellular mechanisms of reduced sarcoplasmic reticulum Ca2+ content in L-thyroxin induced rat ventricular hypertrophy.
    Acta pharmacologica Sinica, 2008, Volume: 29, Issue:4

    Topics: Animals; Caffeine; Calcium; Cardiomegaly; Electrocardiography; Heart Ventricles; Hypertrophy, Left V

2008
Impact of cardiac hypertrophy on arterial and cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetized rats.
    Experimental physiology, 2008, Volume: 93, Issue:9

    Topics: Animals; Baroreflex; Blood Pressure; Body Weight; Caffeine; Cardiomegaly; Central Nervous System Sti

2008
Electrophysiologic properties of hypertrophied myocytes isolated from rats with renal hypertension.
    European heart journal, 1984, Volume: 5 Suppl F

    Topics: Action Potentials; Animals; Caffeine; Calcium; Cardiomegaly; Cells, Cultured; Electric Conductivity;

1984
Effect of hypertrophy on mechanisms of relaxation in isolated cardiac myocytes from guinea pig.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: Animals; Caffeine; Calcium; Calcium-Transporting ATPases; Cardiomegaly; Cells, Cultured; Fluorescent

1994
Diminished effect of cAMP on Ca2+ accumulation in skinned fibers of hypertrophied rat heart.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: Animals; Biological Transport; Caffeine; Calcium; Cardiomegaly; Cyclic AMP; Dose-Response Relationsh

1994
Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin.
    The Journal of clinical investigation, 1998, Apr-01, Volume: 101, Issue:7

    Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium-Binding Proteins; Calsequestrin; Cardiomegaly;

1998
Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure.
    Circulation research, 1999, Nov-26, Volume: 85, Issue:11

    Topics: Animals; Aortic Valve Insufficiency; Arrhythmias, Cardiac; Caffeine; Calcium; Cardiomegaly; Constric

1999
Functional properties of transgenic mouse hearts overexpressing both calsequestrin and the Na(+)-Ca(2+) exchanger.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:2

    Topics: Animals; Body Weight; Caffeine; Calcium; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cal

2000
Low-dose ramipril treatment improves relaxation and calcium cycling after established cardiac hypertrophy.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3

    Topics: Animals; Antihypertensive Agents; Caffeine; Calcium; Calcium-Transporting ATPases; Cardiomegaly; Dos

2001
Antiadrenergic effects of adenosine in pressure overload hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:3

    Topics: Adenosine; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; C

2001
Abnormal calcium and protein kinase C-epsilon signaling in hypertrophied atrial tumor myocytes (AT-1 cells).
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: Animals; Caffeine; Calcium Signaling; Calcium-Transporting ATPases; Cardiomegaly; Cell Differentiati

2001
[Effect of nitric oxide on force-frequency relations in experimental hyperfunction and hypertrophy in the heart muscle].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2001, Volume: 47, Issue:3

    Topics: Action Potentials; Animals; Arginine; Caffeine; Cardiomegaly; Dose-Response Relationship, Drug; Elec

2001
Ca(2+) signaling in cardiac myocytes overexpressing the alpha(1) subunit of L-type Ca(2+) channel.
    Circulation research, 2002, Feb-08, Volume: 90, Issue:2

    Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Calcium-

2002
Left ventricular hypertrophy in rabbits does not exaggerate the effects of halothane on the intracellular components of cardiac contraction.
    Anesthesiology, 1992, Volume: 77, Issue:3

    Topics: Animals; Body Weight; Caffeine; Calcium; Cardiomegaly; Halothane; Male; Myocardial Contraction; Orga

1992
Effect of acidosis on contractile system in skinned fibers of hypertrophied rat heart.
    The American journal of physiology, 1990, Volume: 259, Issue:4 Pt 2

    Topics: Acidosis; Animals; Caffeine; Calcium; Cardiomegaly; Heart; Histological Techniques; Hydrogen-Ion Con

1990
Differential effects of caffeine on skinned fibers from control and hypertrophied ferret hearts.
    The American journal of physiology, 1990, Volume: 259, Issue:6 Pt 2

    Topics: Animals; Caffeine; Calcium; Cardiomegaly; Ferrets; Heart Ventricles; Histological Techniques; Male;

1990
Intracellular calcium related to force development in twitch contraction of mammalian myocardium.
    Cell calcium, 1990, Volume: 11, Issue:8

    Topics: Actin Cytoskeleton; Aequorin; Animals; Caffeine; Calcium; Cardiomegaly; Ferrets; Hyperthyroidism; Is

1990
Altered electrical response to caffeine exposure in hypertrophied rat myocardium.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:12

    Topics: Action Potentials; Animals; Caffeine; Cardiomegaly; Coronary Vessels; Electrophysiology; Female; Iso

1989