caffeine has been researched along with Carcinoma, Hepatocellular in 32 studies
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Caffeine is thought to increase the antitumor effect of cisplatin or DNA-damaging agents because it is known that caffeine inhibits DNA repair." | 5.38 | Caffeine increases the antitumor effect of Cisplatin in human hepatocellular carcinoma cells. ( Arimori, K; Ichimiya, A; Iwakiri, T; Kawano, Y; Kohno, T; Nagata, M; Okumura, M, 2012) |
| " Clearance (Cl) was calculated using the equation of Cl = Kel x Vd (Kel = elimination rate constant, Vd = volume of distribution) and half-life was determined using pharmacokinetic analysis." | 5.31 | Caffeine clearance in patients with hepatocellular carcinoma after transcatheter oily chemoembolization treatment. ( Janchai, A; Mahachai, V; Tangkijvanich, P; Thong-Ngam, D; Thumvijit, L; Wittayalertpanya, S, 2002) |
| " We aimed to investigate the effects of caffeine and its analog CGS 15943 on hepatocellular carcinoma (HCC) and pancreatic cancer adenocarcinoma (PDAC)." | 3.80 | Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway. ( Edling, CE; Falasca, M; Ghonaim, R; Maffucci, T; Selvaggi, F, 2014) |
| "Sorafenib is a multi-kinase inhibitor applicable to hepatocellular carcinoma (HCC), but its limited therapeutic effects are a major problem to be solved." | 3.78 | Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling. ( Aoyagi, Y; Fujimaki, S; Kubota, M; Matsuda, Y; Ohkoshi, S; Sanpei, A; Takamura, M; Wakai, T; Yamagiwa, S; Yano, M, 2012) |
| " We calculated relative risks (RRs) of HCC according to caffeinated and decaffeinated coffee consumption using a random-effects dose-response meta-analysis." | 2.55 | Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: a systematic review and dose-response meta-analysis. ( Buchanan, R; Fallowfield, JA; Hayes, PC; Kennedy, OJ; Parkes, J; Roderick, P, 2017) |
| "Obesity, non-alcoholic fatty liver and steatohepatitis as well as diabetes mellitus together also form a significant risk for HCC, due to the gradually increasing number of patients." | 2.46 | [Role of environmental factors in the etiology of hepatocellular carcinoma]. ( Tornai, I, 2010) |
| " It is currently unknown whether these protective effects are related to caffeine (CAF), or to its combination with other common and/or highly bioavailable coffee compounds, such as trigonelline (TRI) and chlorogenic acid (CGA)." | 1.56 | The combination of coffee compounds attenuates early fibrosis-associated hepatocarcinogenesis in mice: involvement of miRNA profile modulation. ( Barbisan, LF; Cogliati, B; da Silva, TC; Evangelista, AF; Moreno, FS; Prata, GB; Reis, RM; Romualdo, GR; Vinken, M, 2020) |
| "Caffeine has chemopreventive properties, but whether caffeine is responsible for the coffee-HCC association is not well studied." | 1.42 | Coffee Consumption and Risk of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma by Sex: The Liver Cancer Pooling Project. ( Alavanja, MC; Beane-Freeman, LE; Boggs, DA; Buring, JE; Campbell, PT; Chan, AT; Chong, DQ; Freedman, ND; Fuchs, CS; Gapstur, SM; Gaziano, JM; Giovannucci, EL; Graubard, BI; Hollenbeck, AR; King, LY; Koshiol, J; Lai, GY; Lee, IM; Linet, MS; McGlynn, KA; Palmer, JR; Petrick, JL; Poynter, JN; Purdue, MP; Robien, K; Sahasrabuddhe, VV; Schairer, C; Sesso, HD; Sigurdson, AJ; Wactawski-Wende, J; Zeleniuch-Jacquotte, A, 2015) |
| "Caffeine is thought to increase the antitumor effect of cisplatin or DNA-damaging agents because it is known that caffeine inhibits DNA repair." | 1.38 | Caffeine increases the antitumor effect of Cisplatin in human hepatocellular carcinoma cells. ( Arimori, K; Ichimiya, A; Iwakiri, T; Kawano, Y; Kohno, T; Nagata, M; Okumura, M, 2012) |
| " Univariate and multivariate logistic regressions adjusting for age, gender, cigarette smoking, alcohol use, tea consumption and physical activity were conducted with dose-response analysis." | 1.37 | Moderate coffee consumption reduces the risk of hepatocellular carcinoma in hepatitis B chronic carriers: a case-control study. ( Chan, HL; Ho, SC; Leung, WW; Mok, TS; Wong, V; Yeo, W, 2011) |
| "Caffeine has been reported to prevent hepatocarcinogenesis." | 1.35 | Caffeine inhibits the proliferation of liver cancer cells and activates the MEK/ERK/EGFR signalling pathway. ( Matsumoto, K; Murawaki, Y; Nagahara, T; Okano, J, 2008) |
| " Clearance (Cl) was calculated using the equation of Cl = Kel x Vd (Kel = elimination rate constant, Vd = volume of distribution) and half-life was determined using pharmacokinetic analysis." | 1.31 | Caffeine clearance in patients with hepatocellular carcinoma after transcatheter oily chemoembolization treatment. ( Janchai, A; Mahachai, V; Tangkijvanich, P; Thong-Ngam, D; Thumvijit, L; Wittayalertpanya, S, 2002) |
| " Transfected cells were dosed with several known inducers of CYP3A4 and the levels of SPAP were measured." | 1.30 | A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. ( Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM, 1999) |
| "The tumor lines were hepatocellular carcinoma and colon adenocarcinoma." | 1.29 | Differential radiosensitization of radioresistant human cancer cells by caffeine. ( Boonkitticharoen, V; Laohathai, K; Puribhat, S, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.38) | 18.7374 |
| 1990's | 6 (18.75) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 15 (46.88) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Gu, C | 1 |
| Wang, X | 2 |
| Lang, Y | 1 |
| Wu, Y | 1 |
| Wu, X | 1 |
| Zhu, X | 1 |
| Wang, K | 1 |
| Yang, H | 2 |
| Romualdo, GR | 1 |
| Prata, GB | 1 |
| da Silva, TC | 1 |
| Evangelista, AF | 1 |
| Reis, RM | 1 |
| Vinken, M | 1 |
| Moreno, FS | 1 |
| Cogliati, B | 1 |
| Barbisan, LF | 1 |
| Kennedy, OJ | 1 |
| Roderick, P | 1 |
| Buchanan, R | 1 |
| Fallowfield, JA | 1 |
| Hayes, PC | 1 |
| Parkes, J | 1 |
| Oda, Y | 1 |
| Hidaka, M | 1 |
| Suzuki, A | 1 |
| Li, J | 1 |
| Cui, L | 2 |
| Ren, Y | 1 |
| Niu, L | 1 |
| Huang, Y | 1 |
| Saab, S | 1 |
| Mallam, D | 1 |
| Cox, GA | 1 |
| Tong, MJ | 1 |
| Edling, CE | 1 |
| Selvaggi, F | 1 |
| Ghonaim, R | 1 |
| Maffucci, T | 1 |
| Falasca, M | 1 |
| Bamia, C | 1 |
| Lagiou, P | 1 |
| Jenab, M | 1 |
| Trichopoulou, A | 1 |
| Fedirko, V | 1 |
| Aleksandrova, K | 1 |
| Pischon, T | 1 |
| Overvad, K | 1 |
| Olsen, A | 1 |
| Tjønneland, A | 1 |
| Boutron-Ruault, MC | 1 |
| Fagherazzi, G | 1 |
| Racine, A | 1 |
| Kuhn, T | 1 |
| Boeing, H | 1 |
| Floegel, A | 1 |
| Benetou, V | 1 |
| Palli, D | 1 |
| Grioni, S | 1 |
| Panico, S | 1 |
| Tumino, R | 1 |
| Vineis, P | 1 |
| Bueno-de-Mesquita, HB | 1 |
| Dik, VK | 1 |
| Bhoo-Pathy, N | 1 |
| Uiterwaal, CS | 1 |
| Weiderpass, E | 1 |
| Lund, E | 1 |
| Quirós, JR | 1 |
| Zamora-Ros, R | 1 |
| Molina-Montes, E | 1 |
| Chirlaque, MD | 1 |
| Ardanaz, E | 1 |
| Dorronsoro, M | 1 |
| Lindkvist, B | 1 |
| Wallström, P | 1 |
| Nilsson, LM | 1 |
| Sund, M | 1 |
| Khaw, KT | 1 |
| Wareham, N | 1 |
| Bradbury, KE | 1 |
| Travis, RC | 1 |
| Ferrari, P | 1 |
| Duarte-Salles, T | 1 |
| Stepien, M | 1 |
| Gunter, M | 1 |
| Murphy, N | 1 |
| Riboli, E | 1 |
| Trichopoulos, D | 1 |
| Dong, S | 1 |
| Kong, J | 2 |
| Shen, Q | 1 |
| Kong, F | 1 |
| Sun, W | 1 |
| Zheng, L | 1 |
| Petrick, JL | 1 |
| Freedman, ND | 1 |
| Graubard, BI | 1 |
| Sahasrabuddhe, VV | 1 |
| Lai, GY | 1 |
| Alavanja, MC | 1 |
| Beane-Freeman, LE | 1 |
| Boggs, DA | 1 |
| Buring, JE | 1 |
| Chan, AT | 1 |
| Chong, DQ | 1 |
| Fuchs, CS | 1 |
| Gapstur, SM | 1 |
| Gaziano, JM | 1 |
| Giovannucci, EL | 1 |
| Hollenbeck, AR | 1 |
| King, LY | 1 |
| Koshiol, J | 1 |
| Lee, IM | 1 |
| Linet, MS | 1 |
| Palmer, JR | 1 |
| Poynter, JN | 1 |
| Purdue, MP | 1 |
| Robien, K | 1 |
| Schairer, C | 1 |
| Sesso, HD | 1 |
| Sigurdson, AJ | 1 |
| Zeleniuch-Jacquotte, A | 1 |
| Wactawski-Wende, J | 1 |
| Campbell, PT | 1 |
| McGlynn, KA | 1 |
| Mann, CD | 1 |
| Neal, CP | 1 |
| Garcea, G | 1 |
| Manson, MM | 1 |
| Dennison, AR | 1 |
| Berry, DP | 1 |
| Gressner, OA | 1 |
| Wu, JF | 1 |
| Zeng, GL | 1 |
| Shen, W | 1 |
| Yang, M | 1 |
| Wang, F | 1 |
| Tian, L | 1 |
| Li, X | 1 |
| Hu, WY | 1 |
| Li, XP | 1 |
| Ren, H | 1 |
| Tang, KF | 1 |
| Muriel, P | 1 |
| Arauz, J | 1 |
| Tornai, I | 1 |
| Leung, WW | 1 |
| Ho, SC | 1 |
| Chan, HL | 1 |
| Wong, V | 1 |
| Yeo, W | 1 |
| Mok, TS | 1 |
| Fujimaki, S | 1 |
| Matsuda, Y | 1 |
| Wakai, T | 1 |
| Sanpei, A | 1 |
| Kubota, M | 1 |
| Takamura, M | 1 |
| Yamagiwa, S | 1 |
| Yano, M | 1 |
| Ohkoshi, S | 1 |
| Aoyagi, Y | 1 |
| Fujise, Y | 1 |
| Okano, J | 2 |
| Nagahara, T | 2 |
| Abe, R | 1 |
| Imamoto, R | 1 |
| Murawaki, Y | 2 |
| Kawano, Y | 1 |
| Nagata, M | 1 |
| Kohno, T | 1 |
| Ichimiya, A | 1 |
| Iwakiri, T | 1 |
| Okumura, M | 1 |
| Arimori, K | 1 |
| Thong-Ngam, D | 2 |
| Thumvijit, L | 1 |
| Tangkijvanich, P | 2 |
| Janchai, A | 1 |
| Mahachai, V | 2 |
| Wittayalertpanya, S | 2 |
| Higdon, JV | 1 |
| Frei, B | 1 |
| Cadden, IS | 1 |
| Partovi, N | 1 |
| Yoshida, EM | 1 |
| Matsumoto, K | 1 |
| McAleer, WJ | 1 |
| Markus, HZ | 1 |
| Bailey, FJ | 1 |
| Herman, AC | 1 |
| Harder, BJ | 1 |
| Wampler, DE | 1 |
| Miller, WJ | 1 |
| Keller, PM | 1 |
| Buynak, EB | 1 |
| Hilleman, MR | 1 |
| Boonkitticharoen, V | 1 |
| Laohathai, K | 1 |
| Puribhat, S | 1 |
| Sanyal, R | 1 |
| Darroudi, F | 1 |
| Parzefall, W | 1 |
| Nagao, M | 1 |
| Knasmüller, S | 1 |
| Ogg, MS | 1 |
| Williams, JM | 1 |
| Tarbit, M | 1 |
| Goldfarb, PS | 1 |
| Gray, TJ | 1 |
| Gibson, GG | 1 |
| Kusonsolboon, T | 1 |
| Jansen, PL | 1 |
| Chamuleau, RA | 1 |
| van Leeuwen, DJ | 1 |
| Schipper, HG | 1 |
| Busemann-Sokole, E | 1 |
| van der Heyde, MN | 1 |
| Ganapathi, MK | 1 |
| Mackiewicz, A | 1 |
| Samols, D | 1 |
| Brabenec, A | 1 |
| Kushner, I | 1 |
| Schultz, D | 1 |
| Hu, SI | 1 |
| Varagnolo, M | 1 |
| Plebani, M | 1 |
| Mussap, M | 1 |
| Nemetz, L | 1 |
| Paleari, CD | 1 |
| Burlina, A | 1 |
| Cappadona, C | 1 |
| Valguarnera, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuroplastic Alterations of the Motor Cortex by Caffeine: Differences Between Caffeine and Non-caffeine Users and Influence of Vigilance During Stimulation[NCT04011670] | 30 participants (Actual) | Interventional | 2019-07-15 | Completed | |||
| Effect of Coffee and Tea Consumption on Adolescent Weight Control - a Randomized Clinical Trial[NCT05181176] | 63 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | |||
| Cortical Excitability Changes on the Sensorimotor Cortex Induced by Caffeine Consumption: A TMS Study[NCT03720665] | 30 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for caffeine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: a systematic review and dose-response meta-analysis.
Topics: Caffeine; Carcinoma, Hepatocellular; Coffee; Dose-Response Relationship, Drug; Humans; Liver Neoplas | 2017 |
Impact of coffee on liver diseases: a systematic review.
Topics: Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Caffeine; Carcinoma, Hepatocell | 2014 |
Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brassicaceae; Caffeine; Capsaicin; Carcinoma, Hepatocell | 2009 |
Less Smad2 is good for you! A scientific update on coffee's liver benefits.
Topics: Acetylgalactosamine; Animals; Caffeine; Carcinoma, Hepatocellular; Collagen Type I; Connective Tissu | 2009 |
Coffee and liver diseases.
Topics: Animals; Antineoplastic Agents, Phytogenic; Caffeine; Carcinoma, Hepatocellular; Coffee; Diterpenes; | 2010 |
[Role of environmental factors in the etiology of hepatocellular carcinoma].
Topics: Aflatoxins; Alcohol Drinking; Antioxidants; Caffeine; Carcinoma, Hepatocellular; Coffee; Contracepti | 2010 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Coffee and health: a review of recent human research.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Cardiovascular Diseases; Child; Chlorogenic Acid; Coffee | 2006 |
Review article: possible beneficial effects of coffee on liver disease and function.
Topics: Caffeine; Carcinoma, Hepatocellular; Coffee; Humans; Liver Cirrhosis; Liver Neoplasms; Phosphodieste | 2007 |
1 trial available for caffeine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Caffeine clearance study in hepatocellular carcinoma.
Topics: Adult; Aged; Caffeine; Carcinoma, Hepatocellular; Female; Humans; Liver; Liver Cirrhosis; Liver Func | 1999 |
23 other studies available for caffeine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Caffeine enhances the anti-tumor effect of 5-fluorouracil via increasing the production of reactive oxygen species in hepatocellular carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; | 2019 |
The combination of coffee compounds attenuates early fibrosis-associated hepatocarcinogenesis in mice: involvement of miRNA profile modulation.
Topics: Alkaloids; Animals; Anticarcinogenic Agents; Caffeine; Carcinoma, Hepatocellular; Cell Line, Tumor; | 2020 |
Caffeine Has a Synergistic Anticancer Effect with Cisplatin via Inhibiting Fanconi Anemia Group D2 Protein Monoubiquitination in Hepatocellular Carcinoma Cells.
Topics: Antineoplastic Agents; Apoptosis; Caffeine; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferatio | 2017 |
Synergistic cytotoxicity and mechanism of caffeine and lysozyme on hepatoma cell line HepG2.
Topics: Apoptosis; Caffeine; Carcinoma, Hepatocellular; Cell Proliferation; Drug Synergism; Hep G2 Cells; Hu | 2018 |
Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway.
Topics: Antineoplastic Agents; Apoptosis; Caffeine; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; | 2014 |
Coffee, tea and decaffeinated coffee in relation to hepatocellular carcinoma in a European population: multicentre, prospective cohort study.
Topics: Beverages; Caffeine; Carcinoma, Hepatocellular; Case-Control Studies; Coffee; Europe; Female; Humans | 2015 |
Low Concentration of Caffeine Inhibits the Progression of the Hepatocellular Carcinoma via Akt Signaling Pathway.
Topics: Animals; Antineoplastic Agents; Caffeine; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor | 2015 |
Coffee Consumption and Risk of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma by Sex: The Liver Cancer Pooling Project.
Topics: Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Caffeine; Carcinoma, Hepatocellular; Cholangioc | 2015 |
[Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2'-deoxycytidine].
Topics: Ataxia Telangiectasia Mutated Proteins; Azacitidine; Caffeine; Carcinoma, Hepatocellular; Cell Cycle | 2009 |
Moderate coffee consumption reduces the risk of hepatocellular carcinoma in hepatitis B chronic carriers: a case-control study.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Case-Control Studies; Coffee; Dose-Response Relationship | 2011 |
Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling.
Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Benzenesulfonates; Caffeine; Carcinom | 2012 |
Preventive effect of caffeine and curcumin on hepato-carcinogenesis in diethylnitrosamine-induced rats.
Topics: Animals; Anticarcinogenic Agents; Caffeine; Carcinoma, Hepatocellular; Curcumin; Diethylnitrosamine; | 2012 |
Caffeine increases the antitumor effect of Cisplatin in human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Caffeine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Prolif | 2012 |
Caffeine clearance in patients with hepatocellular carcinoma after transcatheter oily chemoembolization treatment.
Topics: Adult; Aged; Analysis of Variance; Caffeine; Carcinoma, Hepatocellular; Chemoembolization, Therapeut | 2002 |
Caffeine inhibits the proliferation of liver cancer cells and activates the MEK/ERK/EGFR signalling pathway.
Topics: Antineoplastic Agents; Apoptosis; Caffeine; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; | 2008 |
Production of purified hepatitis B surface antigen from Alexander hepatoma cells grown in artificial capillary units.
Topics: Caffeine; Carcinoma, Hepatocellular; Cell Line; Chromatography, Affinity; Culture Media; Culture Tec | 1983 |
Differential radiosensitization of radioresistant human cancer cells by caffeine.
Topics: Adenocarcinoma; Caffeine; Carcinoma, Hepatocellular; Colonic Neoplasms; Gamma Rays; Humans; Radiatio | 1993 |
Inhibition of the genotoxic effects of heterocyclic amines in human derived hepatoma cells by dietary bioantimutagens.
Topics: Acrolein; Amines; Antimutagenic Agents; Benzaldehydes; Caffeine; Carbolines; Carcinoma, Hepatocellul | 1997 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofi | 1999 |
Liver regeneration and restoration of liver function after partial hepatectomy in patients with liver tumors.
Topics: Adult; Aged; Caffeine; Carcinoma, Hepatocellular; Female; Galactose; Hepatectomy; Humans; Liver; Liv | 1990 |
Induction of C-reactive protein by cytokines in human hepatoma cell lines is potentiated by caffeine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; C-Reactive Protein; Caffeine; Calcimycin; Calcium; Carcinoma | 1990 |
Caffeine as indicator of metabolic functions of microsomal liver enzymes.
Topics: Adult; Caffeine; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Female; Half-Life; | 1989 |
[Distribution of caffeine in animals with experimental transplantable tumors. Tests with tritium-labeled caffeine for the study of the sensitizing properties].
Topics: Animals; Ascitic Fluid; Caffeine; Carcinoma, Hepatocellular; Kidney; Liver; Liver Neoplasms; Mice; N | 1971 |