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caffeine and Carcinogenesis

caffeine has been researched along with Carcinogenesis in 9 studies

Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Research Excerpts

ExcerptRelevanceReference
" Thus, it was assessed whether caffeine (CAF) and/or chlorogenic acid (CGA) attenuates the early-stage of chemically induced mouse colon carcinogenesis."8.12Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p. ( Barbisan, LF; Bartolomeu, AR; Besharat, ZM; Chaves, MÁG; Corrales, JAM; Lisón, CG; Romualdo, GR, 2022)
"Caffeine ingestion was not significantly different between groups."5.39Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice. ( Bernard, JJ; Conney, AH; Li, T; Lin, Y; Lou, Y; Lu, Y; Nolan, B; Peng, Q; Shih, WJ; Wagner, GC, 2013)
"After due ethical approval, 30 animals were treated with 40mg/kg single dose of 7,12-dimethylbenzene anthracene (DMBA) as a model for DNA damage and induction of carcinogenesis."4.31P53 Gene Expression and Nitric Oxide Levels after Artemisinin-Caffeine Treatment in Breast, Lungs and Liver of DMBA-Induced Tumorigenesis. ( Adelani, BI; Awani, OU; Dokunmu, TM; Enoma, DO; Imaga, NA; Opara, SC, 2023)
" Thus, it was assessed whether caffeine (CAF) and/or chlorogenic acid (CGA) attenuates the early-stage of chemically induced mouse colon carcinogenesis."4.12Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p. ( Barbisan, LF; Bartolomeu, AR; Besharat, ZM; Chaves, MÁG; Corrales, JAM; Lisón, CG; Romualdo, GR, 2022)
"Animal models have suggested that oral or topical administration of caffeine could inhibit ultraviolet-induced carcinogenesis via the ataxia telangiectasia and rad3 (ATR)-related apoptosis."3.83A genome-wide analysis of gene-caffeine consumption interaction on basal cell carcinoma. ( Cornelis, MC; De Vivo, I; Giovannucci, E; Han, J; Li, X; Liang, L; Song, F; Tang, JY, 2016)
"Our previous studies demonstrated that the topical application of caffeine is a potent inhibitor of UVB-induced carcinogenesis and selectively increases apoptosis in tumors but not in non-tumor areas of the epidermis in mice that are at a high risk for developing skin cancer."3.80PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis. ( Bernard, JJ; Li, T; Lou, YR; Lu, YP; Peng, QY, 2014)
" The alkaloids caffeine and trigonelline, as well as the polyphenol chlorogenic acid, are some of the most important bioactive organic compounds of these beverages, displaying high levels in both espresso and common brews and/or increased bioavailability after consumption."2.61Drinking for protection? Epidemiological and experimental evidence on the beneficial effects of coffee or major coffee compounds against gastrointestinal and liver carcinogenesis. ( Barbisan, LF; Chaves, MAG; Cogliati, B; Moreno, FS; Rocha, AB; Romualdo, GR; Vinken, M, 2019)
"Prostate cancer was induced in rats with methylnitrosourea and testosterone and tumor incidence was determined."1.72Effects of green tea on prostate carcinogenesis in rat models and a human prostate cancer xenograft model. ( Bosland, MC; Condon, MS; Horton, L, 2022)
"Caffeine ingestion was not significantly different between groups."1.39Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice. ( Bernard, JJ; Conney, AH; Li, T; Lin, Y; Lou, Y; Lu, Y; Nolan, B; Peng, Q; Shih, WJ; Wagner, GC, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (55.56)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
Bosland, MC1
Horton, L1
Condon, MS1
Lemon, LD1
Kannan, S1
Mo, KW1
Adams, M1
Choi, HG1
Gulka, AOD1
Withers, ES1
Nurelegne, HT1
Gomez, V1
Ambrocio, RE1
Tumminkatti, R1
Lee, RS1
Wan, M1
Fasken, MB1
Spangle, JM1
Corbett, AH1
Bartolomeu, AR1
Romualdo, GR2
Lisón, CG1
Besharat, ZM1
Corrales, JAM1
Chaves, MÁG2
Barbisan, LF3
Dokunmu, TM1
Opara, SC1
Imaga, NA1
Awani, OU1
Enoma, DO1
Adelani, BI1
Rocha, AB1
Vinken, M1
Cogliati, B1
Moreno, FS1
Lou, Y1
Peng, Q1
Li, T2
Nolan, B1
Bernard, JJ2
Wagner, GC1
Lin, Y1
Shih, WJ1
Conney, AH1
Lu, Y1
Furtado, KS1
Polletini, J1
Dias, MC1
Rodrigues, MA1
Lou, YR1
Peng, QY1
Lu, YP1
Li, X1
Cornelis, MC1
Liang, L1
Song, F1
De Vivo, I1
Giovannucci, E1
Tang, JY1
Han, J1

Reviews

1 review available for caffeine and Carcinogenesis

ArticleYear
Drinking for protection? Epidemiological and experimental evidence on the beneficial effects of coffee or major coffee compounds against gastrointestinal and liver carcinogenesis.
    Food research international (Ottawa, Ont.), 2019, Volume: 123

    Topics: Alkaloids; Caffeine; Carcinogenesis; Chlorogenic Acid; Coffea; Coffee; Gastrointestinal Neoplasms; G

2019

Other Studies

8 other studies available for caffeine and Carcinogenesis

ArticleYear
Effects of green tea on prostate carcinogenesis in rat models and a human prostate cancer xenograft model.
    The Prostate, 2022, Volume: 82, Issue:11

    Topics: Animals; Caffeine; Carcinogenesis; Disease Models, Animal; Drinking Water; Heterografts; Humans; Mal

2022
A Saccharomyces cerevisiae model and screen to define the functional consequences of oncogenic histone missense mutations.
    G3 (Bethesda, Md.), 2022, 07-06, Volume: 12, Issue:7

    Topics: Animals; Caffeine; Carcinogenesis; Histone Acetyltransferases; Histones; Humans; Mammals; Mutation;

2022
Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p.
    International journal of molecular sciences, 2022, Jun-04, Volume: 23, Issue:11

    Topics: 1,2-Dimethylhydrazine; Animals; Caffeine; Carcinogenesis; Chlorogenic Acid; Coffee; Colon; Colonic N

2022
P53 Gene Expression and Nitric Oxide Levels after Artemisinin-Caffeine Treatment in Breast, Lungs and Liver of DMBA-Induced Tumorigenesis.
    Asian Pacific journal of cancer prevention : APJCP, 2023, Feb-01, Volume: 24, Issue:2

    Topics: Animals; Anthracenes; Artemisinins; Caffeine; Carcinogenesis; Cell Transformation, Neoplastic; Gene

2023
Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice.
    Nutrition and cancer, 2013, Volume: 65, Issue:7

    Topics: Adipose Tissue; Administration, Oral; Animals; Apoptosis; Caffeine; Carcinogenesis; Chemokines, CC;

2013
Prevention of rat liver fibrosis and carcinogenesis by coffee and caffeine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 64

    Topics: Animals; Blotting, Western; Caffeine; Carcinogenesis; Coffee; Collagen; Glutathione Transferase; Liv

2014
PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Adenine; Animals; Apoptosis; Caffeine; Carcinogenesis; Cyclic Nucleotide Phosphodiesterases, Type 2;

2014
A genome-wide analysis of gene-caffeine consumption interaction on basal cell carcinoma.
    Carcinogenesis, 2016, Volume: 37, Issue:12

    Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Caffeine; Carcinogenesis; Carcinoma, Basal Cell; Ep

2016