caffeine has been researched along with Brain Neoplasms in 22 studies
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 8.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
| "To study the effects and associated mechanisms of caffeine on cell viability, cycle dynamics, proliferation and apoptosis both in glioblastoma C6 and U87MG cells." | 7.81 | Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro. ( Feng, YY; Liu, JD; Song, LJ; Yan, DJ; Yang, Y; Zang, YG, 2015) |
| "We studied the effects of caffeine on cell viability, cell cycle profiles, proliferation, and apoptosis in rat C6 and human U87MG glioblastoma cell lines." | 7.81 | The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas. ( Chen, XP; Jiang, J; Lan, YQ; Li, LH; Liu, XY; Yu, M; Zhang, T, 2015) |
| "We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk." | 7.78 | Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study. ( Darefsky, AS; Dubrow, R; Freedman, ND; Hollenbeck, AR; Sinha, R, 2012) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 5.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "In vitro, caffeine treatment reduced glioma cell proliferation through G(0)/G(1)-phase cell cycle arrest by suppressing Rb phosphorylation." | 5.37 | Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. ( Cho, GJ; Cho, YW; Choi, J; Choi, WS; Jeong, JY; Kang, SS; Kim, HJ; Kim, JS; Ku, BM; Lee, YK; Roh, GS; Ryu, J, 2011) |
| "Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect." | 5.36 | Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. ( Giovannucci, E; Holick, CN; Michaud, DS; Smith, SG, 2010) |
| "Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 4.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
| "To study the effects and associated mechanisms of caffeine on cell viability, cycle dynamics, proliferation and apoptosis both in glioblastoma C6 and U87MG cells." | 3.81 | Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro. ( Feng, YY; Liu, JD; Song, LJ; Yan, DJ; Yang, Y; Zang, YG, 2015) |
| "We studied the effects of caffeine on cell viability, cell cycle profiles, proliferation, and apoptosis in rat C6 and human U87MG glioblastoma cell lines." | 3.81 | The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas. ( Chen, XP; Jiang, J; Lan, YQ; Li, LH; Liu, XY; Yu, M; Zhang, T, 2015) |
| "We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk." | 3.78 | Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study. ( Darefsky, AS; Dubrow, R; Freedman, ND; Hollenbeck, AR; Sinha, R, 2012) |
| " Differentiated human neuroblastoma SH-SY5Y cells were exposed to acrylamide, lindane, parathion, paraoxon, phenytoin, diazepam or caffeine for 72 hours." | 3.74 | Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity. ( Blaauboer, B; Forsby, A, 2007) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 1.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "In vitro, caffeine treatment reduced glioma cell proliferation through G(0)/G(1)-phase cell cycle arrest by suppressing Rb phosphorylation." | 1.37 | Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. ( Cho, GJ; Cho, YW; Choi, J; Choi, WS; Jeong, JY; Kang, SS; Kim, HJ; Kim, JS; Ku, BM; Lee, YK; Roh, GS; Ryu, J, 2011) |
| "Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect." | 1.36 | Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. ( Giovannucci, E; Holick, CN; Michaud, DS; Smith, SG, 2010) |
| "Caffeine treatment potentiated the BCNU-induced accumulation of cells in late-S-G2-M phase of the cell cycle." | 1.27 | Effect of caffeine on cytotoxicity and sister chromatid exchange induction in sensitive and resistant rat brain tumor cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Aida, T; Bodell, WJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (27.27) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JC | 1 |
| Hwang, JH | 1 |
| Liu, JD | 1 |
| Song, LJ | 1 |
| Yan, DJ | 1 |
| Feng, YY | 1 |
| Zang, YG | 1 |
| Yang, Y | 1 |
| Jiang, J | 1 |
| Lan, YQ | 1 |
| Zhang, T | 1 |
| Yu, M | 1 |
| Liu, XY | 1 |
| Li, LH | 1 |
| Chen, XP | 1 |
| Cheng, YC | 1 |
| Ding, YM | 1 |
| Hueng, DY | 1 |
| Chen, JY | 1 |
| Chen, Y | 1 |
| Holick, CN | 1 |
| Smith, SG | 1 |
| Giovannucci, E | 1 |
| Michaud, DS | 1 |
| Sinn, B | 1 |
| Tallen, G | 1 |
| Schroeder, G | 1 |
| Grassl, B | 1 |
| Schulze, J | 1 |
| Budach, V | 1 |
| Tinhofer, I | 1 |
| Ku, BM | 1 |
| Lee, YK | 1 |
| Jeong, JY | 1 |
| Ryu, J | 1 |
| Choi, J | 1 |
| Kim, JS | 1 |
| Cho, YW | 1 |
| Roh, GS | 1 |
| Kim, HJ | 1 |
| Cho, GJ | 1 |
| Choi, WS | 1 |
| Kang, SS | 1 |
| Vartanian, LP | 3 |
| Kolesova, MB | 2 |
| Gornaeva, GF | 2 |
| Pustovalov, IuI | 1 |
| Dubrow, R | 1 |
| Darefsky, AS | 1 |
| Freedman, ND | 1 |
| Hollenbeck, AR | 1 |
| Sinha, R | 1 |
| POPEK, K | 1 |
| Forsby, A | 1 |
| Blaauboer, B | 1 |
| Nakamura, H | 1 |
| Wun, KL | 1 |
| Shafer, RH | 1 |
| Jacobi, G | 1 |
| Ritz, A | 1 |
| Berger, T | 1 |
| Janss, AJ | 1 |
| Levow, C | 1 |
| Bernhard, EJ | 1 |
| Muschel, RJ | 1 |
| McKenna, WG | 1 |
| Sutton, L | 1 |
| Phillips, PC | 1 |
| Borbé, R | 1 |
| Rieger, J | 1 |
| Weller, M | 1 |
| Saqr, HE | 1 |
| Guan, Z | 1 |
| Yates, AJ | 1 |
| Stokes, BT | 1 |
| Bostel, S | 1 |
| Malo, M | 1 |
| Rouzaire-Dubois, B | 1 |
| Dubois, JM | 1 |
| Krutovskikh, GN | 1 |
| Girshovich, MZ | 1 |
| Rudenko, IIa | 1 |
| Volchkov, VA | 1 |
| Stewart, DJ | 1 |
| Hugenholtz, H | 1 |
| DaSilva, V | 1 |
| Benoit, B | 1 |
| Richard, M | 1 |
| Russell, N | 1 |
| Maroun, J | 1 |
| Verma, S | 1 |
| Aida, T | 1 |
| Bodell, WJ | 1 |
1 review available for caffeine and Brain Neoplasms
| Article | Year |
|---|---|
[Liposomal boron delivery system for neutron capture therapy].
Topics: Animals; Boron Neutron Capture Therapy; Brain Neoplasms; Caffeine; Chlorpheniramine; Codeine; Drug C | 2008 |
21 other studies available for caffeine and Brain Neoplasms
| Article | Year |
|---|---|
Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats.
Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Caffeine; Cell Line, Tumor; Endoplasmic Reticulum St | 2022 |
Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Surviva | 2015 |
The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cel | 2015 |
Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Brain Neoplasms; Caffeine; Cathepsin | 2016 |
Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies.
Topics: Adult; Aged; Brain Neoplasms; Caffeine; Coffee; Cohort Studies; Diet; Female; Glioma; Humans; Male; | 2010 |
Caffeine confers radiosensitization of PTEN-deficient malignant glioma cells by enhancing ionizing radiation-induced G1 arrest and negatively regulating Akt phosphorylation.
Topics: Animals; Brain Neoplasms; Caffeine; Cell Line, Tumor; Cell Survival; DNA Damage; G1 Phase; Gene Expr | 2010 |
Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2011 |
[Caffeine derivatives: research perspectives in antitumor and radio-modified drugs for the combined treatment of malignant brain tumors].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Caffeine; DNA Repair; Humans; | 2010 |
Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study.
Topics: Aged; Brain Neoplasms; Caffeine; Carbonated Beverages; Coffee; Cohort Studies; Female; Glioma; Human | 2012 |
THE STUDY OF CHANGES IN THE SO-CALLED SUCCESSIVE CONTRAST IN NEUROLOGY.
Topics: Afterimage; Amphetamine; Arteriosclerosis; Brain Concussion; Brain Injuries; Brain Neoplasms; Bromid | 1964 |
Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity.
Topics: Acrylamide; Animals; Anticonvulsants; Brain Neoplasms; Caffeine; Calcium Channels; Central Nervous S | 2007 |
Structural changes in mammalian cell DNA induced by low-dose x-ray damage and subsequent postirradiation incubation in the presence and absence of caffeine.
Topics: Animals; Brain Neoplasms; Caffeine; Cell Line; DNA Repair; DNA, Neoplasm; Dose-Response Relationship | 1982 |
[Migraine in children. Clinics, differential diagnosis, and therapy (author's transl)].
Topics: Adolescent; Analgesics; Brain Neoplasms; Caffeine; Cerebral Angiography; Cerebrovascular Disorders; | 1981 |
Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines.
Topics: Apoptosis; Brain Neoplasms; Caffeine; Camptothecin; Cisplatin; Drug Screening Assays, Antitumor; Dru | 1998 |
Failure of taxol-based combination chemotherapy for malignant glioma cannot be overcome by G2/M checkpoint abrogators or altering the p53 status.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; G2 Phase; Genes, p53; Gli | 1999 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium | 1999 |
Calcium and voltage-dependent alterations of cell volume in neuroblastomaxglioma hybrid NG108-15 cells.
Topics: Brain Neoplasms; Caffeine; Calcimycin; Calcium; Cell Size; Chloride Channels; Electric Stimulation; | 2002 |
[Proxyphein chemotherapy in experimental glioma of the brain in rats].
Topics: Animals; Brain Neoplasms; Caffeine; Glioma; Rats; Time Factors | 1990 |
[The radiation therapy of experimental brain tumors by using the radiosensitizing preparation xanthobin (8-bromocaffeine)].
Topics: Animals; Brain Neoplasms; Caffeine; Drug Evaluation, Preclinical; Glioma; Metronidazole; Neoplasm Tr | 1989 |
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; Carmustine; Cisplatin; Cy | 1987 |
Effect of caffeine on cytotoxicity and sister chromatid exchange induction in sensitive and resistant rat brain tumor cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Brain Neoplasms; Caffeine; Carmustine; Cell Line; Cell Survival; DNA Damage; DNA Repair; Dr | 1987 |