caffeine has been researched along with Benign Neoplasms, Brain in 22 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 8.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
| "To study the effects and associated mechanisms of caffeine on cell viability, cycle dynamics, proliferation and apoptosis both in glioblastoma C6 and U87MG cells." | 7.81 | Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro. ( Feng, YY; Liu, JD; Song, LJ; Yan, DJ; Yang, Y; Zang, YG, 2015) |
| "We studied the effects of caffeine on cell viability, cell cycle profiles, proliferation, and apoptosis in rat C6 and human U87MG glioblastoma cell lines." | 7.81 | The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas. ( Chen, XP; Jiang, J; Lan, YQ; Li, LH; Liu, XY; Yu, M; Zhang, T, 2015) |
| "We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk." | 7.78 | Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study. ( Darefsky, AS; Dubrow, R; Freedman, ND; Hollenbeck, AR; Sinha, R, 2012) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 5.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "In vitro, caffeine treatment reduced glioma cell proliferation through G(0)/G(1)-phase cell cycle arrest by suppressing Rb phosphorylation." | 5.37 | Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. ( Cho, GJ; Cho, YW; Choi, J; Choi, WS; Jeong, JY; Kang, SS; Kim, HJ; Kim, JS; Ku, BM; Lee, YK; Roh, GS; Ryu, J, 2011) |
| "Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect." | 5.36 | Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. ( Giovannucci, E; Holick, CN; Michaud, DS; Smith, SG, 2010) |
| "Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)." | 4.12 | Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022) |
| "To study the effects and associated mechanisms of caffeine on cell viability, cycle dynamics, proliferation and apoptosis both in glioblastoma C6 and U87MG cells." | 3.81 | Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro. ( Feng, YY; Liu, JD; Song, LJ; Yan, DJ; Yang, Y; Zang, YG, 2015) |
| "We studied the effects of caffeine on cell viability, cell cycle profiles, proliferation, and apoptosis in rat C6 and human U87MG glioblastoma cell lines." | 3.81 | The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas. ( Chen, XP; Jiang, J; Lan, YQ; Li, LH; Liu, XY; Yu, M; Zhang, T, 2015) |
| "We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk." | 3.78 | Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study. ( Darefsky, AS; Dubrow, R; Freedman, ND; Hollenbeck, AR; Sinha, R, 2012) |
| " Differentiated human neuroblastoma SH-SY5Y cells were exposed to acrylamide, lindane, parathion, paraoxon, phenytoin, diazepam or caffeine for 72 hours." | 3.74 | Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity. ( Blaauboer, B; Forsby, A, 2007) |
| "Glioblastoma has aggressive proliferative and invasive properties." | 1.43 | Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ( Chen, JY; Chen, Y; Cheng, YC; Ding, YM; Hueng, DY, 2016) |
| "In vitro, caffeine treatment reduced glioma cell proliferation through G(0)/G(1)-phase cell cycle arrest by suppressing Rb phosphorylation." | 1.37 | Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. ( Cho, GJ; Cho, YW; Choi, J; Choi, WS; Jeong, JY; Kang, SS; Kim, HJ; Kim, JS; Ku, BM; Lee, YK; Roh, GS; Ryu, J, 2011) |
| "Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect." | 1.36 | Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. ( Giovannucci, E; Holick, CN; Michaud, DS; Smith, SG, 2010) |
| "Caffeine treatment potentiated the BCNU-induced accumulation of cells in late-S-G2-M phase of the cell cycle." | 1.27 | Effect of caffeine on cytotoxicity and sister chromatid exchange induction in sensitive and resistant rat brain tumor cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Aida, T; Bodell, WJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (27.27) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JC | 1 |
| Hwang, JH | 1 |
| Liu, JD | 1 |
| Song, LJ | 1 |
| Yan, DJ | 1 |
| Feng, YY | 1 |
| Zang, YG | 1 |
| Yang, Y | 1 |
| Jiang, J | 1 |
| Lan, YQ | 1 |
| Zhang, T | 1 |
| Yu, M | 1 |
| Liu, XY | 1 |
| Li, LH | 1 |
| Chen, XP | 1 |
| Cheng, YC | 1 |
| Ding, YM | 1 |
| Hueng, DY | 1 |
| Chen, JY | 1 |
| Chen, Y | 1 |
| Holick, CN | 1 |
| Smith, SG | 1 |
| Giovannucci, E | 1 |
| Michaud, DS | 1 |
| Sinn, B | 1 |
| Tallen, G | 1 |
| Schroeder, G | 1 |
| Grassl, B | 1 |
| Schulze, J | 1 |
| Budach, V | 1 |
| Tinhofer, I | 1 |
| Ku, BM | 1 |
| Lee, YK | 1 |
| Jeong, JY | 1 |
| Ryu, J | 1 |
| Choi, J | 1 |
| Kim, JS | 1 |
| Cho, YW | 1 |
| Roh, GS | 1 |
| Kim, HJ | 1 |
| Cho, GJ | 1 |
| Choi, WS | 1 |
| Kang, SS | 1 |
| Vartanian, LP | 3 |
| Kolesova, MB | 2 |
| Gornaeva, GF | 2 |
| Pustovalov, IuI | 1 |
| Dubrow, R | 1 |
| Darefsky, AS | 1 |
| Freedman, ND | 1 |
| Hollenbeck, AR | 1 |
| Sinha, R | 1 |
| POPEK, K | 1 |
| Forsby, A | 1 |
| Blaauboer, B | 1 |
| Nakamura, H | 1 |
| Wun, KL | 1 |
| Shafer, RH | 1 |
| Jacobi, G | 1 |
| Ritz, A | 1 |
| Berger, T | 1 |
| Janss, AJ | 1 |
| Levow, C | 1 |
| Bernhard, EJ | 1 |
| Muschel, RJ | 1 |
| McKenna, WG | 1 |
| Sutton, L | 1 |
| Phillips, PC | 1 |
| Borbé, R | 1 |
| Rieger, J | 1 |
| Weller, M | 1 |
| Saqr, HE | 1 |
| Guan, Z | 1 |
| Yates, AJ | 1 |
| Stokes, BT | 1 |
| Bostel, S | 1 |
| Malo, M | 1 |
| Rouzaire-Dubois, B | 1 |
| Dubois, JM | 1 |
| Krutovskikh, GN | 1 |
| Girshovich, MZ | 1 |
| Rudenko, IIa | 1 |
| Volchkov, VA | 1 |
| Stewart, DJ | 1 |
| Hugenholtz, H | 1 |
| DaSilva, V | 1 |
| Benoit, B | 1 |
| Richard, M | 1 |
| Russell, N | 1 |
| Maroun, J | 1 |
| Verma, S | 1 |
| Aida, T | 1 |
| Bodell, WJ | 1 |
1 review available for caffeine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
[Liposomal boron delivery system for neutron capture therapy].
Topics: Animals; Boron Neutron Capture Therapy; Brain Neoplasms; Caffeine; Chlorpheniramine; Codeine; Drug C | 2008 |
21 other studies available for caffeine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats.
Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Caffeine; Cell Line, Tumor; Endoplasmic Reticulum St | 2022 |
Caffeine inhibits the growth of glioblastomas through activating the caspase-3 signaling pathway in vitro.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Surviva | 2015 |
The in vitro effects of caffeine on viability, cycle cycle profiles, proliferation, and apoptosis of glioblastomas.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cel | 2015 |
Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Brain Neoplasms; Caffeine; Cathepsin | 2016 |
Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies.
Topics: Adult; Aged; Brain Neoplasms; Caffeine; Coffee; Cohort Studies; Diet; Female; Glioma; Humans; Male; | 2010 |
Caffeine confers radiosensitization of PTEN-deficient malignant glioma cells by enhancing ionizing radiation-induced G1 arrest and negatively regulating Akt phosphorylation.
Topics: Animals; Brain Neoplasms; Caffeine; Cell Line, Tumor; Cell Survival; DNA Damage; G1 Phase; Gene Expr | 2010 |
Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells.
Topics: Animals; Apoptosis; Brain Neoplasms; Caffeine; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2011 |
[Caffeine derivatives: research perspectives in antitumor and radio-modified drugs for the combined treatment of malignant brain tumors].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Caffeine; DNA Repair; Humans; | 2010 |
Coffee, tea, soda, and caffeine intake in relation to risk of adult glioma in the NIH-AARP Diet and Health Study.
Topics: Aged; Brain Neoplasms; Caffeine; Carbonated Beverages; Coffee; Cohort Studies; Female; Glioma; Human | 2012 |
THE STUDY OF CHANGES IN THE SO-CALLED SUCCESSIVE CONTRAST IN NEUROLOGY.
Topics: Afterimage; Amphetamine; Arteriosclerosis; Brain Concussion; Brain Injuries; Brain Neoplasms; Bromid | 1964 |
Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity.
Topics: Acrylamide; Animals; Anticonvulsants; Brain Neoplasms; Caffeine; Calcium Channels; Central Nervous S | 2007 |
Structural changes in mammalian cell DNA induced by low-dose x-ray damage and subsequent postirradiation incubation in the presence and absence of caffeine.
Topics: Animals; Brain Neoplasms; Caffeine; Cell Line; DNA Repair; DNA, Neoplasm; Dose-Response Relationship | 1982 |
[Migraine in children. Clinics, differential diagnosis, and therapy (author's transl)].
Topics: Adolescent; Analgesics; Brain Neoplasms; Caffeine; Cerebral Angiography; Cerebrovascular Disorders; | 1981 |
Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines.
Topics: Apoptosis; Brain Neoplasms; Caffeine; Camptothecin; Cisplatin; Drug Screening Assays, Antitumor; Dru | 1998 |
Failure of taxol-based combination chemotherapy for malignant glioma cannot be overcome by G2/M checkpoint abrogators or altering the p53 status.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; G2 Phase; Genes, p53; Gli | 1999 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium | 1999 |
Calcium and voltage-dependent alterations of cell volume in neuroblastomaxglioma hybrid NG108-15 cells.
Topics: Brain Neoplasms; Caffeine; Calcimycin; Calcium; Cell Size; Chloride Channels; Electric Stimulation; | 2002 |
[Proxyphein chemotherapy in experimental glioma of the brain in rats].
Topics: Animals; Brain Neoplasms; Caffeine; Glioma; Rats; Time Factors | 1990 |
[The radiation therapy of experimental brain tumors by using the radiosensitizing preparation xanthobin (8-bromocaffeine)].
Topics: Animals; Brain Neoplasms; Caffeine; Drug Evaluation, Preclinical; Glioma; Metronidazole; Neoplasm Tr | 1989 |
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; Carmustine; Cisplatin; Cy | 1987 |
Effect of caffeine on cytotoxicity and sister chromatid exchange induction in sensitive and resistant rat brain tumor cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Animals; Brain Neoplasms; Caffeine; Carmustine; Cell Line; Cell Survival; DNA Damage; DNA Repair; Dr | 1987 |