caffeine has been researched along with Arthritis, Rheumatoid in 25 studies
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylxanthines, like caffeine, have been thought to reverse the antiinflammatory effects of methotrexate (MTX) in rheumatoid arthritis (RA)." | 9.12 | Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis. ( Benito-Garcia, E; Bilics, JA; Chibnik, LB; Heller, JE; Maher, NE; Matthews, HM; Shadick, NA; Weinblatt, ME, 2006) |
| "Studies indicate that caffeine uptake may be a risk factor for rheumatoid arthritis (RA), but a definitive link between caffeine consumption and RA has not been established." | 8.12 | Adenosine receptor A2a blockade by caffeine increases IFN-gamma production in Th1 cells from patients with rheumatoid arthritis. ( Breuninger, M; Gloyer, L; Golumba-Nagy, V; Jochimsen, D; Kofler, DM; Meyer, A; Schiller, J; Yan, S, 2022) |
| "To evaluate whether coffee, tea, and caffeine consumption are risk factors for rheumatoid arthritis (RA) onset among older women." | 7.71 | Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: results from the Iowa Women's Health Study. ( Burma, M; Cerhan, JR; Criswell, LA; Folsom, AR; Merlino, L; Mikuls, TR; Mudano, AS; Saag, KG, 2002) |
| "This therapeutic protein-drug interaction study evaluated the disease-mediated effect of sirukumab (anti-interleukin 6 [anti-IL-6] monoclonal antibody) on the pharmacokinetics of the cytochrome P450 (CYP) probe substrates midazolam (CYP3A), omeprazole (CYP2C19), warfarin (CYP2C9), and caffeine (CYP1A2) in patients with active rheumatoid arthritis (RA)." | 5.20 | Evaluation of disease-mediated therapeutic protein-drug interactions between an anti-interleukin-6 monoclonal antibody (sirukumab) and cytochrome P450 activities in a phase 1 study in patients with rheumatoid arthritis using a cocktail approach. ( Chen, D; Davis, HM; de Vries, DE; Leon, F; Marciniak, SJ; Xu, Z; Zhou, H; Zhuang, Y, 2015) |
| "Methylxanthines, like caffeine, have been thought to reverse the antiinflammatory effects of methotrexate (MTX) in rheumatoid arthritis (RA)." | 5.12 | Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis. ( Benito-Garcia, E; Bilics, JA; Chibnik, LB; Heller, JE; Maher, NE; Matthews, HM; Shadick, NA; Weinblatt, ME, 2006) |
| "Studies indicate that caffeine uptake may be a risk factor for rheumatoid arthritis (RA), but a definitive link between caffeine consumption and RA has not been established." | 4.12 | Adenosine receptor A2a blockade by caffeine increases IFN-gamma production in Th1 cells from patients with rheumatoid arthritis. ( Breuninger, M; Gloyer, L; Golumba-Nagy, V; Jochimsen, D; Kofler, DM; Meyer, A; Schiller, J; Yan, S, 2022) |
| "We intend to assess the effect of the conditioned medium of Caffeine pulsed MSCS in the amelioration of rheumatoid arthritis (RA)-afflicted rats." | 3.96 | Immunomodulatory benefits of mesenchymal stem cells treated with Caffeine in adjuvant-induced arthritis. ( Abtahi Froushani, SM; Moases Ghaffary, E, 2020) |
| "To evaluate whether coffee, tea, and caffeine consumption are risk factors for rheumatoid arthritis (RA) onset among older women." | 3.71 | Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: results from the Iowa Women's Health Study. ( Burma, M; Cerhan, JR; Criswell, LA; Folsom, AR; Merlino, L; Mikuls, TR; Mudano, AS; Saag, KG, 2002) |
| "Caffeine has been found to potentiate the acute anti-inflammatory activity of aspirin, indomethacin, and phenylbutazone, but not the activity of sodium salicylate or hydrocortisone, in the carrageenan pleurisy or hindlimb models of inflammation in the rat." | 3.65 | Potentiation of the anti-inflammatory and analgesic activity of aspirin by caffeine in the rat. ( Ellis, CH; Selph, JL; Truax, JF; Vinegar, R; Welch, RM; White, HL, 1976) |
| "A survey of 763 patients with rheumatoid arthritis and 145 with osteoarthritis in six clinics in New Zealand showed no association between aspirin intake and a score designed to detect analgesic nephropathy." | 3.65 | Aspirin and the kidney. New Zealand Rheumatism Association Study. ( , 1974) |
| "Caffeine is a widely consumed pharmacologically active product." | 1.48 | Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity. ( Iris, M; Sawalha, AH; Tsou, PS, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (40.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 4 (16.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gloyer, L | 1 |
| Golumba-Nagy, V | 1 |
| Meyer, A | 1 |
| Yan, S | 1 |
| Schiller, J | 1 |
| Breuninger, M | 1 |
| Jochimsen, D | 1 |
| Kofler, DM | 1 |
| Ingegnoli, F | 1 |
| Cavalli, S | 1 |
| Giudice, L | 1 |
| Caporali, R | 1 |
| Wang, S | 1 |
| Han, Y | 1 |
| Zhao, H | 1 |
| Han, X | 1 |
| Yin, Y | 1 |
| Wu, J | 1 |
| Zhang, Y | 1 |
| Zeng, X | 1 |
| Moases Ghaffary, E | 1 |
| Abtahi Froushani, SM | 1 |
| Iris, M | 1 |
| Tsou, PS | 1 |
| Sawalha, AH | 1 |
| Zhuang, Y | 1 |
| de Vries, DE | 1 |
| Xu, Z | 1 |
| Marciniak, SJ | 1 |
| Chen, D | 1 |
| Leon, F | 1 |
| Davis, HM | 1 |
| Zhou, H | 1 |
| Malaviya, AN | 1 |
| Nesher, G | 1 |
| Mates, M | 1 |
| Zevin, S | 1 |
| Bazzi, A | 1 |
| Portnoff, K | 1 |
| Pischel, KD | 1 |
| VON FRESENIUS, H | 1 |
| CARINCI, MP | 1 |
| SERVERDUPUY, JM | 1 |
| Karlson, EW | 1 |
| Mandl, LA | 1 |
| Aweh, GN | 1 |
| Grodstein, F | 1 |
| Benito-Garcia, E | 1 |
| Heller, JE | 1 |
| Chibnik, LB | 1 |
| Maher, NE | 1 |
| Matthews, HM | 1 |
| Bilics, JA | 1 |
| Weinblatt, ME | 1 |
| Shadick, NA | 1 |
| Grober, SE | 1 |
| Mikuls, TR | 1 |
| Cerhan, JR | 1 |
| Criswell, LA | 1 |
| Merlino, L | 1 |
| Mudano, AS | 1 |
| Burma, M | 1 |
| Folsom, AR | 1 |
| Saag, KG | 1 |
| Vinegar, R | 1 |
| Truax, JF | 1 |
| Selph, JL | 1 |
| Welch, RM | 1 |
| White, HL | 1 |
| Ellis, CH | 1 |
| Liliemark, J | 1 |
| Pettersson, B | 1 |
| Lafolie, P | 1 |
| Zweig, T | 1 |
| Peterson, C | 1 |
| Wyngaarden, JB | 1 |
| Hill, RC | 1 |
| Turner, P | 1 |
| Edwards, KD | 1 |
| Schapel, GJ | 1 |
| Jeremy, R | 1 |
| Steele, TW | 1 |
| Thorpe, P | 1 |
| Jick, H | 1 |
| Slone, D | 1 |
| Dinan, B | 1 |
| Muench, H | 1 |
1 review available for caffeine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Caffeine and rheumatoid arthritis: A complicated relationship.
Topics: Arthritis, Rheumatoid; Caffeine; Comorbidity; Humans; Inflammation | 2022 |
5 trials available for caffeine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Evaluation of disease-mediated therapeutic protein-drug interactions between an anti-interleukin-6 monoclonal antibody (sirukumab) and cytochrome P450 activities in a phase 1 study in patients with rheumatoid arthritis using a cocktail approach.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Rheum | 2015 |
Dietary caffeine intake does not affect methotrexate efficacy in patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Caffeine; Central Nervous System Stimulants; Cohort Stu | 2006 |
A comparison of codeine compound and "saridone" in the pain of rheumatoid arthritis.
Topics: Adult; Aged; Antipyrine; Arthritis, Rheumatoid; Caffeine; Clinical Trials as Topic; Codeine; Female; | 1970 |
An assessment of "Fiorinal" and FIPA in painful conditions of the hands.
Topics: Acetaminophen; Adult; Aged; Analgesics; Analysis of Variance; Arthritis, Rheumatoid; Aspirin; Caffei | 1970 |
Evaluation of drug efficacy by a preference technic.
Topics: Arthritis, Rheumatoid; Aspirin; Caffeine; Dexamethasone; Dextropropoxyphene; Humans; Hypnotics and S | 1966 |
19 other studies available for caffeine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Adenosine receptor A2a blockade by caffeine increases IFN-gamma production in Th1 cells from patients with rheumatoid arthritis.
Topics: Adenosine A2 Receptor Antagonists; Arthritis, Rheumatoid; Caffeine; Humans; Interferon-gamma; Leukoc | 2022 |
Association between Coffee Consumption, Caffeine Intake, and Metabolic Syndrome Severity in Patients with Self-Reported Rheumatoid Arthritis: National Health and Nutrition Examination Survey 2003-2018.
Topics: Arthritis, Rheumatoid; Caffeine; Coffee; Humans; Metabolic Syndrome; Nutrition Surveys; Risk Factors | 2022 |
Immunomodulatory benefits of mesenchymal stem cells treated with Caffeine in adjuvant-induced arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Caffeine; Dose-Response Relationship, Drug; | 2020 |
Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity.
Topics: Arthritis, Rheumatoid; Autoimmunity; Caffeine; Central Nervous System Stimulants; Cytokines; Down-Re | 2018 |
Methotrexate intolerance in the treatment of rheumatoid arthritis (RA): effect of adding caffeine to the management regimen.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Caffeine; Chocolate; Coffee; Drug Therapy, | 2017 |
Effect of caffeine consumption on efficacy of methotrexate in rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Caffeine; Coffee; Drug Interactions; Female; Hum | 2003 |
Is decaf a decoy? Comment on the article by Mikuls et al.
Topics: Aged; Arthritis, Rheumatoid; Caffeine; Central Nervous System Stimulants; Coffee; Drinking Behavior; | 2003 |
[Therapeutic significance of impletol].
Topics: Arthritis; Arthritis, Rheumatoid; Caffeine; Cold Temperature; Cryotherapy; Drug Combinations; Humans | 1952 |
[Clinical experience with a new analgesic drug combination].
Topics: Acepromazine; Analgesics; Arthritis; Arthritis, Rheumatoid; Aspirin; Caffeine; Drug Combinations; Hu | 1962 |
[THE CUFF METHOD FOR THE ANTALGIC EVALUATION OF DIFFERENT DRUGS].
Topics: Aminopyrine; Arthritis; Arthritis, Rheumatoid; Aspirin; Caffeine; Gout; Osteoarthritis; Phenobarbita | 1963 |
Coffee consumption and risk of rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Caffeine; Central Nervous System Stimulants; Coffee; Drinking Behavior | 2003 |
Coffee or decaff?
Topics: Arthritis, Rheumatoid; Caffeine; Coffee; Humans; Rheumatoid Factor | 2001 |
Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: results from the Iowa Women's Health Study.
Topics: Aged; Arthritis, Rheumatoid; Caffeine; Central Nervous System Stimulants; Coffee; Drinking Behavior; | 2002 |
Ditch the decaf?
Topics: Arthritis, Rheumatoid; Caffeine; Coffee; Female; Humans; United States | 2002 |
Potentiation of the anti-inflammatory and analgesic activity of aspirin by caffeine in the rat.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Caffeine; Cyclooxygenase Inhibitors; Drug Therapy, Combinat | 1976 |
Determination of plasma azathioprine and 6-mercaptopurine in patients with rheumatoid arthritis treated with oral azathioprine.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathioprine; | 1990 |
From the National Institutes of Health.
Topics: Arthritis, Rheumatoid; Caffeine; Cyclosporins; Female; Fertility; Humans; Osteoporosis; Sodium Fluor | 1989 |
Aspirin and the kidney. New Zealand Rheumatism Association Study.
Topics: Acetaminophen; Adult; Arthritis, Rheumatoid; Aspirin; Caffeine; Codeine; Drug Synergism; Female; Hum | 1974 |
Possible nephrotoxicity of aspirin in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Caffeine; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Ph | 1972 |