caffeine has been researched along with Arrhythmias, Cardiac in 116 studies
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Caffeine (300 mg) was administered to each of 70 patients a mean (+/- standard error of the mean) of 7 +/- 1 days after the onset of acute myocardial infarction to determine its effects on ventricular arrhythmias." | 9.06 | Caffeine as a possible cause of ventricular arrhythmias during the healing phase of acute myocardial infarction. ( Grant, DM; Harris, L; Leenen, FH; Myers, MG, 1987) |
| "The effect of high dose caffeine on ventricular arrhythmias was examined in 35 patients with recent myocardial infarctions." | 9.06 | High dose caffeine and ventricular arrhythmias. ( Harris, L; Myers, MG, 1990) |
| "Little information is known regarding caffeine's effect on the substrate supporting sustained ventricular arrhythmias." | 9.06 | Caffeine and ventricular arrhythmias. An electrophysiological approach. ( Chelsky, LB; Cutler, JE; Griffith, K; Kron, J; McAnulty, JH; McClelland, JH, 1990) |
| "Apnea of prematurity (AOP) is a significant clinical problem manifested by an unstable respiratory rhythm reflecting the immaturity of respiratory control systems." | 8.87 | Apnea of prematurity: pathogenesis and management strategies. ( Mathew, OP, 2011) |
| "Limited data exist on the safety and physiologic effects of caffeine in patients with known arrhythmias." | 8.87 | Caffeine and cardiac arrhythmias: a review of the evidence. ( Goldberger, JJ; Pelchovitz, DJ, 2011) |
| "In one electrophysiologic study, caffeine was associated with an increased susceptibility to provoked cardiac arrhythmias." | 8.78 | Caffeine and cardiac arrhythmias. ( Myers, MG, 1991) |
| "Ryanodine receptor 2 (RyR2) hyperactivity is observed in structural heart diseases that are a result of ischemia or heart failure." | 8.31 | Ryanodine receptor inhibition with acute dantrolene treatment reduces arrhythmia susceptibility in human hearts. ( Brennan-McLean, JA; Efimov, IR; Faye, NR; George, SA; Knollmann, BC; Rytkin, E; Trampel, KA, 2023) |
| "In this experimental whole-heart study, treatment with caffeine and taurine provoked ventricular arrhythmias." | 8.12 | Cardiovascular risk of energy drinks: Caffeine and taurine facilitate ventricular arrhythmias in a sensitive whole-heart model. ( Eckardt, L; Ellermann, C; Frommeyer, G; Hakenes, T; Leitz, P; Rath, B; Wegner, FK; Willy, K; Wolfes, J, 2022) |
| "The present study established a model of RyR(2) knockdown cardiomyocytes and elucidated the role of RyR(2) in aconitine-induced arrhythmia." | 7.74 | Sarcoplasmic reticulum Ca2+ release channel ryanodine receptor (RyR2) plays a crucial role in aconitine-induced arrhythmias. ( Fan, L; Fu, M; He, GW; Li, RX; Thornburg, KL; Wang, Z, 2008) |
| "Physicians and pharmacists should be alerted to the potential adverse effects of phenylpropanolamine-containing products, which may include exaggerated hypertensive effects, arrhythmias (premature ventricular and atrial contractions together with paroxysmal ventricular or atrial tachycardia), psychotic reactions, and neurologic effects (grand mal seizures and intracerebral hemorrhage)." | 7.66 | Cardiac arrhythmias after phenylpropanolamine ingestion. ( Clark, JE; Simon, WA, 1983) |
| "The interaction between arrhythmia episodes and certain lifestyle factors such as obesity and alcohol is well established." | 6.58 | Caffeine and Arrhythmias: Time to Grind the Data. ( Kalman, JM; Kistler, PM; Voskoboinik, A, 2018) |
| "Medium dose induced significant S." | 6.40 | Caffeine and cardiac arrhythmias. An experimental study in dogs with review of literature. ( Billie, M; Jain, AC; Mehta, A; Mehta, MC, 1997) |
| "Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation." | 5.48 | Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018) |
| "Ephedrine is a sympathicomimetic agent that stimulates the central nervous and cardiovascular systems and causes bronchodilatation." | 5.31 | [Ephedrine and ephedra in weight loss products and other preparations]. ( Stricker, BH; van der Hooft, CS, 2002) |
| "A wide spectrum of cardiac arrhythmias was observed during and following the seizures." | 5.26 | Caffeine- and aminophylline-induced seizures. ( Chu, NS, 1981) |
| "Although moderate caffeine ingestion has not been shown to be arrhythmogenic, caffeine toxicity can cause severe cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia." | 5.08 | Acute effects of caffeine ingestion on signal-averaged electrocardiograms. ( Bender, AM; Donnerstein, RL; Goldberg, SJ; Samson, R; Zhu, D, 1998) |
| "The effect of high dose caffeine on ventricular arrhythmias was examined in 35 patients with recent myocardial infarctions." | 5.06 | High dose caffeine and ventricular arrhythmias. ( Harris, L; Myers, MG, 1990) |
| "Little information is known regarding caffeine's effect on the substrate supporting sustained ventricular arrhythmias." | 5.06 | Caffeine and ventricular arrhythmias. An electrophysiological approach. ( Chelsky, LB; Cutler, JE; Griffith, K; Kron, J; McAnulty, JH; McClelland, JH, 1990) |
| "Caffeine (300 mg) was administered to each of 70 patients a mean (+/- standard error of the mean) of 7 +/- 1 days after the onset of acute myocardial infarction to determine its effects on ventricular arrhythmias." | 5.06 | Caffeine as a possible cause of ventricular arrhythmias during the healing phase of acute myocardial infarction. ( Grant, DM; Harris, L; Leenen, FH; Myers, MG, 1987) |
| " On the other hand, overconsumption of chocolate can lead to tachyarrhythmias, supraventricular tachycardia, atrial fibrillation, ventricular tachycardia and ventricular fibrillation due to its caffeine content." | 4.98 | Impact of chocolate on the cardiovascular health. ( Bergante, S; D'Orazio, N; Efthymakis, K; Gammone, MA; Pluchinotta, FR; Riccioni, G; Tettamanti, G, 2018) |
| "Apnea of prematurity (AOP) is a significant clinical problem manifested by an unstable respiratory rhythm reflecting the immaturity of respiratory control systems." | 4.87 | Apnea of prematurity: pathogenesis and management strategies. ( Mathew, OP, 2011) |
| "Limited data exist on the safety and physiologic effects of caffeine in patients with known arrhythmias." | 4.87 | Caffeine and cardiac arrhythmias: a review of the evidence. ( Goldberger, JJ; Pelchovitz, DJ, 2011) |
| "In one electrophysiologic study, caffeine was associated with an increased susceptibility to provoked cardiac arrhythmias." | 4.78 | Caffeine and cardiac arrhythmias. ( Myers, MG, 1991) |
| "Ryanodine receptor 2 (RyR2) hyperactivity is observed in structural heart diseases that are a result of ischemia or heart failure." | 4.31 | Ryanodine receptor inhibition with acute dantrolene treatment reduces arrhythmia susceptibility in human hearts. ( Brennan-McLean, JA; Efimov, IR; Faye, NR; George, SA; Knollmann, BC; Rytkin, E; Trampel, KA, 2023) |
| "In this experimental whole-heart study, treatment with caffeine and taurine provoked ventricular arrhythmias." | 4.12 | Cardiovascular risk of energy drinks: Caffeine and taurine facilitate ventricular arrhythmias in a sensitive whole-heart model. ( Eckardt, L; Ellermann, C; Frommeyer, G; Hakenes, T; Leitz, P; Rath, B; Wegner, FK; Willy, K; Wolfes, J, 2022) |
| " ECG telemetry revealed that various types of arrhythmias were induced in RyR2(R420W/R420W) mice in response to administration of caffeine and adrenaline." | 3.80 | A knock-in mouse model of N-terminal R420W mutation of cardiac ryanodine receptor exhibits arrhythmogenesis with abnormal calcium dynamics in cardiomyocytes. ( Hirata, Y; Kuwahara, M; Nishio, H; Oku, Y; Okudaira, N, 2014) |
| "The present study established a model of RyR(2) knockdown cardiomyocytes and elucidated the role of RyR(2) in aconitine-induced arrhythmia." | 3.74 | Sarcoplasmic reticulum Ca2+ release channel ryanodine receptor (RyR2) plays a crucial role in aconitine-induced arrhythmias. ( Fan, L; Fu, M; He, GW; Li, RX; Thornburg, KL; Wang, Z, 2008) |
| "Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited disease characterized by life threatening arrhythmias and mutations in the gene encoding the ryanodine receptor (RyR2)." | 3.73 | Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model. ( Colombi, B; Imbriani, M; Lai, FA; Liu, N; Memmi, M; Napolitano, C; Negri, S; Priori, SG; Rizzi, N; Zissimopoulos, S, 2006) |
| " No arrhythmia occurred in the presence of ryanodine (10(-6) M) alone, but addition of either caffeine (10 mM) or high Ca2+ (10." | 3.69 | Electrophysiological actions of ryanodine on single rabbit sinoatrial nodal cells. ( Satoh, H, 1997) |
| "In an acute experiment in healthy volunteers and in patients under long-term treatment for cardiac arrhythmias, mexiletine inhibits caffeine elimination by about 50%." | 3.67 | Influence of mexiletine on caffeine elimination. ( Epping, J; Heusler, H; Joeres, R; Klinker, H; Richter, E, 1987) |
| "Physicians and pharmacists should be alerted to the potential adverse effects of phenylpropanolamine-containing products, which may include exaggerated hypertensive effects, arrhythmias (premature ventricular and atrial contractions together with paroxysmal ventricular or atrial tachycardia), psychotic reactions, and neurologic effects (grand mal seizures and intracerebral hemorrhage)." | 3.66 | Cardiac arrhythmias after phenylpropanolamine ingestion. ( Clark, JE; Simon, WA, 1983) |
| " The most frequent adverse events (AEs) were headache (60 %) and palpitations (40 %)." | 2.78 | Cardiovascular safety of anagrelide in healthy subjects: effects of caffeine and food intake on pharmacokinetics and adverse reactions. ( Datino, T; Fernández-Avilés, F; Figueiras-Graillet, L; Franklin, R; Gama, JG; Jones, C; Martínez-Sellés, M, 2013) |
| "The interaction between arrhythmia episodes and certain lifestyle factors such as obesity and alcohol is well established." | 2.58 | Caffeine and Arrhythmias: Time to Grind the Data. ( Kalman, JM; Kistler, PM; Voskoboinik, A, 2018) |
| "Medium dose induced significant S." | 2.40 | Caffeine and cardiac arrhythmias. An experimental study in dogs with review of literature. ( Billie, M; Jain, AC; Mehta, A; Mehta, MC, 1997) |
| "Caffeine is a methylxanthine whose primary biologic effect is antagonism of the adenosine receptor." | 2.38 | Wake up and smell the coffee. Caffeine, coffee, and the medical consequences. ( Chou, T, 1992) |
| "Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation." | 1.48 | Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018) |
| "To better understand LQTS arrhythmias, we performed current-clamp and intracellular calcium ([Ca(2+)]i) measurements on cardiomyocytes differentiated from patient-derived induced pluripotent stem cells (iPS-CM)." | 1.40 | Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. ( Aalto-Setälä, K; Baba, S; Balijepalli, S; Conklin, BR; Fu, CC; Hayashi, Y; Healy, KE; Hua, EA; January, CT; Kamp, TJ; Lizarraga, P; Makielski, JC; Nakamura, K; Scheinman, MM; Sears, MA; Spencer, CI; Tomoda, K; Wojciak, J; Yamanaka, S; Zhang, J, 2014) |
| " The incidence of moderate to major adverse effects of energy drink-related toxicity was 15." | 1.39 | An analysis of energy-drink toxicity in the National Poison Data System. ( Arheart, KL; Benson, BE; Bronstein, AC; Franco, VI; Hershorin, ER; Lipshultz, SE; Schaechter, JL; Seifert, SA; Seifert, SM, 2013) |
| "Myocardial stunning is a contractile dysfunction that occurs after a brief ischaemic insult." | 1.36 | Transient Ca2+ depletion of the sarcoplasmic reticulum at the onset of reperfusion. ( Escobar, AL; Ferreiro, M; Kornyeyev, D; Mattiazzi, A; Petrosky, AD; Valverde, CA, 2010) |
| "Cerebral ischemic model was made by middle cerebral artery occlusion (MCAO)." | 1.35 | Aberration of L-type calcium channel in cardiac myocytes is one of the mechanisms of arrhythmia induced by cerebral ischemia. ( Du, J; Pan, G; Sun, L; Wang, L; Yang, B; Zhang, G; Zhang, Y, 2008) |
| "The implications of these results for arrhythmias associated with abnormal ryanodine receptors are discussed." | 1.34 | Increasing ryanodine receptor open probability alone does not produce arrhythmogenic calcium waves: threshold sarcoplasmic reticulum calcium content is required. ( Eisner, DA; Trafford, AW; Venetucci, LA, 2007) |
| "In an arrhythmia-promoting model (dogs subjected to 7-day atrial tachypacing), Ca(2+)-transient amplitude and kinetics were the same in cells from both pulmonary veins and atrium." | 1.33 | Comparison of Ca2+-handling properties of canine pulmonary vein and left atrial cardiomyocytes. ( Chartier, D; Coutu, P; Nattel, S, 2006) |
| "Ventricular arrhythmias and contractile dysfunction are the main causes of death in human heart failure (HF)." | 1.31 | Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. ( Bers, DM; Li, L; Pogwizd, SM; Schlotthauer, K; Yuan, W, 2001) |
| "Ephedrine is a sympathicomimetic agent that stimulates the central nervous and cardiovascular systems and causes bronchodilatation." | 1.31 | [Ephedrine and ephedra in weight loss products and other preparations]. ( Stricker, BH; van der Hooft, CS, 2002) |
| " In phase I, 30 experiments were performed in our laboratories to study the dose-response curves of both the drugs." | 1.30 | Combined effects of caffeine and alcohol on hemodynamics and coronary artery blood flow in dogs. ( Billie, M; Jain, AC; Mehta, MC, 1999) |
| "Treatment of cardiac arrhythmia by repeated intravenous injections of propranolol (1 mg/kg) or verapamil (1 mg/kg) was effective and prolonged survival time to 91." | 1.30 | Experimental treatment of the acute cardiovascular toxicity of caffeine. ( Diederich, KW; Strubelt, O, 1999) |
| "In situations of [Ca2+]i-overload, arrhythmias are believed to be triggered by delayed afterdepolarizations, which are generated by a transient inward current ITI." | 1.30 | Characterization of a [Ca2+]i-dependent current in human atrial and ventricular cardiomyocytes in the absence of Na+ and K+. ( Beuckelmann, DJ; Köster, OF; Szigeti, GP, 1999) |
| "To determine clinical electrophysiologic effects of a moderate dose of caffeine, we compared prevailing cardiac rhythm and rate, the prevalence and frequency of ventricular dysrhythmia, and Q-T intervals in two populations over an initial 24-hour caffeine-free period and a subsequent 24-hour period in which caffeine was ingested in a dosage of 1 mg/kg of body weight at intervals of one half-life during waking hours." | 1.27 | The effect of caffeine on cardiac rate, rhythm, and ventricular repolarization. Analysis of 18 normal subjects and 18 patients with primary ventricular dysrhythmia. ( McPherson, DD; Montague, TJ; Renton, KW; Spencer, CA; Sutherland, DJ, 1985) |
| "Caffeine half-life was calculated for each subject and caffeine was then ingested at 1 mg/kg every 0." | 1.27 | High-dose caffeine and cardiac rate and rhythm in normal subjects. ( Montague, TJ; Newcombe, PF; Rautaharju, PM; Renton, KW; Spencer, CA, 1988) |
| " Differences among high, moderate and low users were common, and some dose-response associations were apparent." | 1.26 | Somatic manifestations of caffeinism. ( Greden, JF; Lubetsky, M; Victor, BS, 1981) |
| "A wide spectrum of cardiac arrhythmias was observed during and following the seizures." | 1.26 | Caffeine- and aminophylline-induced seizures. ( Chu, NS, 1981) |
| "This model for malignant hyperpyrexia resembles the naturally occurring disease more closely than several preceding pharmacologic models." | 1.26 | A laboratory animal model for malignant hyperpyrexia. ( Durbin, CG; Rosenberg, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (22.41) | 18.7374 |
| 1990's | 23 (19.83) | 18.2507 |
| 2000's | 27 (23.28) | 29.6817 |
| 2010's | 32 (27.59) | 24.3611 |
| 2020's | 8 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Ellermann, C | 1 |
| Hakenes, T | 1 |
| Wolfes, J | 1 |
| Wegner, FK | 1 |
| Willy, K | 1 |
| Leitz, P | 1 |
| Rath, B | 1 |
| Eckardt, L | 1 |
| Frommeyer, G | 1 |
| El Moheb, M | 1 |
| Refaat, MM | 1 |
| Souza, DS | 1 |
| Marques, LP | 1 |
| Costa, AD | 1 |
| Cruz, JS | 1 |
| Rhana, P | 1 |
| Santos-Miranda, A | 1 |
| Joviano-Santos, JV | 1 |
| Durço, AO | 1 |
| Vasconcelos, CML | 1 |
| Roman-Campos, D | 1 |
| George, SA | 1 |
| Brennan-McLean, JA | 1 |
| Trampel, KA | 1 |
| Rytkin, E | 1 |
| Faye, NR | 1 |
| Knollmann, BC | 2 |
| Efimov, IR | 1 |
| Wren, LM | 1 |
| DeKeyser, JM | 1 |
| Barefield, DY | 1 |
| Hawkins, NA | 1 |
| McNally, EM | 1 |
| Kearney, JA | 1 |
| Wasserstrom, JA | 1 |
| George, AL | 1 |
| Posch, MI | 1 |
| Kay, MD | 1 |
| Harhash, AA | 1 |
| Huang, JJ | 1 |
| Krupinski, EA | 1 |
| Abidov, A | 1 |
| McMillan, NA | 1 |
| Kuo, PH | 1 |
| Piccioni, A | 1 |
| Covino, M | 1 |
| Zanza, C | 1 |
| Longhitano, Y | 1 |
| Tullo, G | 1 |
| Bonadia, N | 1 |
| Rinninella, E | 1 |
| Ojetti, V | 1 |
| Gasbarrini, A | 1 |
| Franceschi, F | 1 |
| Maiese, A | 1 |
| La Russa, R | 1 |
| Del Fante, Z | 1 |
| Turillazzi, E | 1 |
| David, MC | 1 |
| Frati, P | 1 |
| Fineschi, V | 1 |
| Fletcher, EA | 1 |
| Lacey, CS | 1 |
| Aaron, M | 1 |
| Kolasa, M | 1 |
| Occiano, A | 1 |
| Shah, SA | 1 |
| Ko, CY | 1 |
| Liu, MB | 1 |
| Song, Z | 1 |
| Qu, Z | 1 |
| Weiss, JN | 1 |
| Gammone, MA | 1 |
| Efthymakis, K | 1 |
| Pluchinotta, FR | 1 |
| Bergante, S | 1 |
| Tettamanti, G | 1 |
| Riccioni, G | 1 |
| D'Orazio, N | 1 |
| Hallas, T | 1 |
| Eisen, B | 1 |
| Shemer, Y | 1 |
| Ben Jehuda, R | 1 |
| Mekies, LN | 1 |
| Naor, S | 1 |
| Schick, R | 1 |
| Eliyahu, S | 1 |
| Reiter, I | 1 |
| Vlodavsky, E | 1 |
| Katz, YS | 1 |
| Õunap, K | 1 |
| Lorber, A | 1 |
| Rodenburg, R | 1 |
| Mandel, H | 1 |
| Gherghiceanu, M | 1 |
| Binah, O | 1 |
| Takemoto, H | 1 |
| Takahashi, J | 1 |
| Hyuga, S | 1 |
| Odaguchi, H | 1 |
| Uchiyama, N | 1 |
| Maruyama, T | 1 |
| Yamashita, T | 1 |
| Hyuga, M | 1 |
| Oshima, N | 1 |
| Amakura, Y | 1 |
| Hakamatsuka, T | 1 |
| Goda, Y | 1 |
| Hanawa, T | 1 |
| Kobayashi, Y | 1 |
| Kim, H | 1 |
| Park, S | 1 |
| Kim, EY | 1 |
| Park, J | 1 |
| Voskoboinik, A | 1 |
| Kalman, JM | 1 |
| Kistler, PM | 1 |
| Poussel, M | 1 |
| Kimmoun, A | 1 |
| Levy, B | 1 |
| Gambier, N | 1 |
| Dudek, F | 1 |
| Puskarczyk, E | 1 |
| Poussel, JF | 1 |
| Chenuel, B | 1 |
| Seifert, SM | 2 |
| Seifert, SA | 2 |
| Schaechter, JL | 2 |
| Bronstein, AC | 2 |
| Benson, BE | 2 |
| Hershorin, ER | 2 |
| Arheart, KL | 2 |
| Franco, VI | 2 |
| Lipshultz, SE | 2 |
| Zhou, YH | 1 |
| Piao, XM | 1 |
| Liu, X | 1 |
| Liang, HH | 1 |
| Wang, LM | 1 |
| Xiong, XH | 1 |
| Wang, L | 3 |
| Lu, YJ | 1 |
| Shan, HL | 1 |
| Chen, W | 2 |
| Wang, R | 2 |
| Chen, B | 1 |
| Zhong, X | 1 |
| Kong, H | 1 |
| Bai, Y | 1 |
| Zhou, Q | 1 |
| Xie, C | 1 |
| Zhang, J | 4 |
| Guo, A | 1 |
| Tian, X | 1 |
| Jones, PP | 1 |
| O'Mara, ML | 1 |
| Liu, Y | 1 |
| Mi, T | 1 |
| Zhang, L | 1 |
| Bolstad, J | 2 |
| Semeniuk, L | 1 |
| Cheng, H | 1 |
| Chen, J | 1 |
| Tieleman, DP | 1 |
| Gillis, AM | 1 |
| Duff, HJ | 1 |
| Fill, M | 1 |
| Song, LS | 1 |
| Chen, SR | 2 |
| Banerjee, P | 1 |
| Ali, Z | 1 |
| Levine, B | 1 |
| Fowler, DR | 1 |
| Barker, KA | 1 |
| Seger, D | 2 |
| Okudaira, N | 1 |
| Kuwahara, M | 1 |
| Hirata, Y | 1 |
| Oku, Y | 1 |
| Nishio, H | 1 |
| Yamakawa, H | 1 |
| Murata, M | 1 |
| Suzuki, T | 1 |
| Yada, H | 1 |
| Ishida, H | 1 |
| Aizawa, Y | 1 |
| Adachi, T | 1 |
| Kamiya, K | 1 |
| Fukuda, K | 1 |
| Spencer, CI | 1 |
| Baba, S | 1 |
| Nakamura, K | 1 |
| Hua, EA | 1 |
| Sears, MA | 1 |
| Fu, CC | 1 |
| Balijepalli, S | 1 |
| Tomoda, K | 1 |
| Hayashi, Y | 1 |
| Lizarraga, P | 1 |
| Wojciak, J | 1 |
| Scheinman, MM | 1 |
| Aalto-Setälä, K | 1 |
| Makielski, JC | 1 |
| January, CT | 1 |
| Healy, KE | 1 |
| Kamp, TJ | 1 |
| Yamanaka, S | 1 |
| Conklin, BR | 1 |
| Nakamura, Y | 1 |
| Nakano, M | 1 |
| Nakamura, M | 1 |
| Miyazaki, D | 1 |
| Okamori, S | 1 |
| Akuzawa, H | 1 |
| Yuasa, M | 1 |
| Myles, RC | 1 |
| Bers, DM | 4 |
| Ripplinger, CM | 1 |
| Sanchis-Gomar, F | 1 |
| Pareja-Galeano, H | 1 |
| Cervellin, G | 1 |
| Lippi, G | 1 |
| Earnest, CP | 1 |
| Elitok, A | 1 |
| Öz, F | 1 |
| Panc, C | 1 |
| Sarıkaya, R | 1 |
| Sezikli, S | 1 |
| Pala, Y | 1 |
| Bugan, ÖS | 1 |
| Ateş, M | 1 |
| Parıldar, H | 1 |
| Ayaz, MB | 1 |
| Atıcı, A | 1 |
| Oflaz, H | 1 |
| Savio-Galimberti, E | 1 |
| Fabrizio, C | 1 |
| Desiderio, M | 1 |
| Coyne, RF | 1 |
| Asirvatham, SJ | 1 |
| Stevenson, WG | 1 |
| Radnic, B | 1 |
| Radojevic, N | 1 |
| Vucinic, J | 1 |
| Duborija-Kovacevic, N | 1 |
| Sun, L | 1 |
| Du, J | 1 |
| Zhang, G | 1 |
| Zhang, Y | 5 |
| Pan, G | 1 |
| Yang, B | 1 |
| Yuan, Q | 1 |
| Han, P | 1 |
| Dong, M | 1 |
| Ren, X | 1 |
| Zhou, X | 1 |
| Chen, S | 1 |
| Jones, WK | 1 |
| Chu, G | 1 |
| Wang, HS | 1 |
| Kranias, EG | 1 |
| Schwiening, C | 2 |
| Killeen, MJ | 2 |
| Ma, A | 1 |
| Lei, M | 1 |
| Grace, AA | 2 |
| Huang, CL | 2 |
| Chen, WP | 1 |
| Hung, LM | 1 |
| Hsueh, CH | 1 |
| Lai, LP | 1 |
| Su, MJ | 1 |
| Richardson, T | 1 |
| Baker, J | 1 |
| Thomas, PW | 1 |
| Meckes, C | 1 |
| Rozkovec, A | 1 |
| Kerr, D | 1 |
| Stevens, SC | 1 |
| Terentyev, D | 1 |
| Kalyanasundaram, A | 1 |
| Periasamy, M | 1 |
| Györke, S | 1 |
| Hirose, M | 1 |
| Stuyvers, BD | 2 |
| Dun, W | 1 |
| ter Keurs, HE | 2 |
| Boyden, PA | 2 |
| Jones, SA | 1 |
| Yamamoto, M | 1 |
| Tellez, JO | 1 |
| Billeter, R | 1 |
| Boyett, MR | 1 |
| Honjo, H | 1 |
| Lancaster, MK | 1 |
| Niggli, E | 1 |
| Fraser, JA | 1 |
| Valverde, CA | 1 |
| Kornyeyev, D | 1 |
| Ferreiro, M | 1 |
| Petrosky, AD | 1 |
| Mattiazzi, A | 1 |
| Escobar, AL | 1 |
| Liu, N | 2 |
| Ruan, Y | 1 |
| Denegri, M | 1 |
| Bachetti, T | 1 |
| Li, Y | 1 |
| Colombi, B | 2 |
| Napolitano, C | 2 |
| Coetzee, WA | 1 |
| Priori, SG | 2 |
| Mathew, OP | 1 |
| Pelchovitz, DJ | 1 |
| Goldberger, JJ | 1 |
| Dufendach, KA | 1 |
| Horner, JM | 1 |
| Cannon, BC | 1 |
| Ackerman, MJ | 1 |
| Martínez-Sellés, M | 1 |
| Datino, T | 1 |
| Figueiras-Graillet, L | 1 |
| Gama, JG | 1 |
| Jones, C | 1 |
| Franklin, R | 1 |
| Fernández-Avilés, F | 1 |
| van der Hooft, CS | 1 |
| Stricker, BH | 1 |
| MEZZASALMA, G | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Energy Drink Consumption on ECG and Hemodynamic Parameters in Young Healthy Volunteers[NCT02023723] | 18 participants (Actual) | Interventional | 2013-12-31 | Completed | |||
| The Effect of Energy Drink Ingredients on Cardiovascular Function[NCT04149717] | 35 participants (Anticipated) | Interventional | 2020-01-01 | Recruiting | |||
| The Effect of Energy Drink on Cardiovascular Variables: A Randomized Controlled Trial[NCT03841838] | 20 participants (Actual) | Interventional | 2019-02-23 | Completed | |||
| Comparison of Synthetic and Natural Caffeine on Hemodynamic Parameters in Young, Healthy Volunteers: A Randomized, Double Blind, Crossover Study[NCT03495063] | 0 participants (Actual) | Interventional | 2019-09-16 | Withdrawn (stopped due to Unable to quantify caffeine) | |||
| Evaluation of Energy Drink Consumption on Electrocardiographic, Vascular and Hematologic Parameters in Young Healthy Volunteers: A Randomized, Double Blind, Active-Controlled, Crossover Study[NCT03021616] | 2 participants (Actual) | Interventional | 2017-06-26 | Terminated (stopped due to Results from sister study at University of the Pacific were conclusive.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 reviews available for caffeine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Energy drinks: a narrative review of their physiological and pathological effects.
Topics: Arrhythmias, Cardiac; Caffeine; Energy Drinks; Humans; Long QT Syndrome; Taurine | 2021 |
Impact of chocolate on the cardiovascular health.
Topics: Antioxidants; Arrhythmias, Cardiac; Cacao; Caffeine; Cardiotonic Agents; Central Nervous System Stim | 2018 |
Caffeine and Arrhythmias: Time to Grind the Data.
Topics: Arrhythmias, Cardiac; Caffeine; Central Nervous System Stimulants; Coffee; Energy Drinks; Humans; My | 2018 |
Energy drink overconsumption in adolescents: implications for arrhythmias and other cardiovascular events.
Topics: Adolescent; Adolescent Behavior; Arrhythmias, Cardiac; Caffeine; Cardiovascular Diseases; Energy Dri | 2015 |
Apnea of prematurity: pathogenesis and management strategies.
Topics: Apnea; Arrhythmias, Cardiac; Brain Stem; Caffeine; Central Nervous System Stimulants; Continuous Pos | 2011 |
Caffeine and cardiac arrhythmias: a review of the evidence.
Topics: Arrhythmias, Cardiac; Caffeine; Humans | 2011 |
Cardiovascular sequelae of tobacco smoking.
Topics: Aortic Aneurysm, Abdominal; Arrhythmias, Cardiac; Atherosclerosis; Caffeine; Cardiovascular Diseases | 2006 |
[Coffee and caffeine. Various selected aspects for everyday practice].
Topics: Arrhythmias, Cardiac; Blood Pressure; Caffeine; Coffee; Humans; Neoplasms; Risk Factors; Xanthines | 1993 |
Intracellular calcium modulators for cardiac muscle in pathological conditions.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Benzothiazoles; Caffeine; Ca | 1996 |
Caffeine and cardiac arrhythmias. An experimental study in dogs with review of literature.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Dogs; Dose-Response Relationship, Drug; Electrocardiography | 1997 |
Wake up and smell the coffee. Caffeine, coffee, and the medical consequences.
Topics: Arrhythmias, Cardiac; Beverages; Caffeine; Catecholamines; Coffee; Coronary Disease; Humans; Pancrea | 1992 |
Caffeine and cardiac arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Electrophysiology; Heart; Humans; In Vitro Techniques | 1991 |
Treatment of petroleum distillate ingestion.
Topics: Accidents, Home; Age Factors; Arrhythmias, Cardiac; Caffeine; Child, Preschool; Emetics; Gastric Lav | 1971 |
[Cardiovascular effect of caffeine and coffee in animals and man].
Topics: Administration, Oral; Amphibians; Animals; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Capillari | 1969 |
7 trials available for caffeine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Pressure; Caffeine; Central Nervous System Stimulants | 2017 |
Randomized control trial investigating the influence of coffee on heart rate variability in patients with ST-segment elevation myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Caffeine; Coffee; Double-Blind Method; Electro | 2009 |
Cardiovascular safety of anagrelide in healthy subjects: effects of caffeine and food intake on pharmacokinetics and adverse reactions.
Topics: Adolescent; Adult; Analysis of Variance; Area Under Curve; Arrhythmias, Cardiac; Biotransformation; | 2013 |
Acute effects of caffeine ingestion on signal-averaged electrocardiograms.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double | 1998 |
High dose caffeine and ventricular arrhythmias.
Topics: Aged; Arrhythmias, Cardiac; Caffeine; Cardiac Complexes, Premature; Clinical Trials as Topic; Coffee | 1990 |
Caffeine and ventricular arrhythmias. An electrophysiological approach.
Topics: Adult; Aged; Arrhythmias, Cardiac; Caffeine; Cardiac Pacing, Artificial; Catecholamines; Chromatogra | 1990 |
Caffeine as a possible cause of ventricular arrhythmias during the healing phase of acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Blood Pressure; Caffeine; Cardiac Complexes, Premature; Double-Blind Method; E | 1987 |
95 other studies available for caffeine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Cardiovascular risk of energy drinks: Caffeine and taurine facilitate ventricular arrhythmias in a sensitive whole-heart model.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Cardiovascular Diseases; Energy Drinks; | 2022 |
The impact of caffeine and taurine on ventricular arrhythmias.
Topics: Arrhythmias, Cardiac; Caffeine; Heart Ventricles; Humans; Taurine | 2022 |
Experimental hypothyroidism induces cardiac arrhythmias and ranolazine reverts and prevents the phenotype.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Dobutamine; Hypothyroidism; Male; Methim | 2022 |
Ryanodine receptor inhibition with acute dantrolene treatment reduces arrhythmia susceptibility in human hearts.
Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeine; Calcium; Dantrolene; Hear | 2023 |
Sex and Gene Influence Arrhythmia Susceptibility in Murine Models of Calmodulinopathy.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calmodulin; Disease Models, Animal; Epinephrine; Female; Ge | 2023 |
Daily Caffeine Consumption Is Associated with Decreased Incidence of Symptoms and Hemodynamic Changes During Pharmacologic Stress with Regadenoson.
Topics: Adenosine A2 Receptor Agonists; Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Blood Pressure; Ca | 2020 |
Massive β1-Adrenergic Receptor Reaction Explains Irreversible Acute Arrhythmia in a Fatal Case of Acute Pure Caffeine Intoxication.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Central Nervous System Stimulants; Epinephrine; Fatal Outcome | 2021 |
Multiscale Determinants of Delayed Afterdepolarization Amplitude in Cardiac Tissue.
Topics: Aniline Compounds; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Signaling; Cardiovascul | 2017 |
Investigating the cardiac pathology of SCO2-mediated hypertrophic cardiomyopathy using patients induced pluripotent stem cell-derived cardiomyocytes.
Topics: Action Potentials; Adult; Arrhythmias, Cardiac; Caffeine; Cardiomyopathy, Hypertrophic; Carrier Prot | 2018 |
Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias.
Topics: Alkaloids; Analgesics, Non-Narcotic; Animals; Animals, Outbred Strains; Anxiety; Arrhythmias, Cardia | 2018 |
Retrospective multi-phase non-contrast-enhanced magnetic resonance angiography (ROMANCE MRA) for robust angiogram separation in the presence of cardiac arrhythmia.
Topics: Algorithms; Arrhythmias, Cardiac; Caffeine; Contrast Media; Healthy Volunteers; Humans; Image Enhanc | 2018 |
Fatal cardiac arrhythmia following voluntary caffeine overdose in an amateur body-builder athlete.
Topics: Adult; Arrhythmias, Cardiac; Athletes; Caffeine; Drug Overdose; Fatal Outcome; Humans; Male; Weight | 2013 |
An analysis of energy-drink toxicity in the National Poison Data System.
Topics: Adolescent; Adult; Alcoholic Beverages; Arrhythmias, Cardiac; Caffeine; Central Nervous System Stimu | 2013 |
Arrhythmogenesis toxicity of aconitine is related to intracellular ca(2+) signals.
Topics: Aconitine; Animals; Arrhythmias, Cardiac; Blotting, Western; Caffeine; Calcium; Cells, Cultured; Mal | 2013 |
The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; DNA Primers; Echocardiography; Gene Knock-In Techn | 2014 |
Fatal caffeine intoxication: a series of eight cases from 1999 to 2009.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Cardiomyopathy, Dilated; Central Nervous System Stimulants; C | 2014 |
In reply to "Interpretation of 'An analysis of energy-drink toxicity in the National Poison Data System'".
Topics: Alcoholic Beverages; Arrhythmias, Cardiac; Caffeine; Central Nervous System Stimulants; Energy Drink | 2014 |
Interpretation of "An analysis of energy-drink toxicity in the National Poison Data System".
Topics: Alcoholic Beverages; Arrhythmias, Cardiac; Caffeine; Central Nervous System Stimulants; Energy Drink | 2014 |
A knock-in mouse model of N-terminal R420W mutation of cardiac ryanodine receptor exhibits arrhythmogenesis with abnormal calcium dynamics in cardiomyocytes.
Topics: Action Potentials; Amino Acid Substitution; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calciu | 2014 |
Suppression of Rad leads to arrhythmogenesis via PKA-mediated phosphorylation of ryanodine receptor activity in the heart.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Signaling; Cyclic AMP-D | 2014 |
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.
Topics: Action Potentials; Arrhythmias, Cardiac; Caffeine; Calcium; Cell Differentiation; Ether-A-Go-Go Pota | 2014 |
[Case of law-evading herbs poisoning that induced shock and myocardial damage].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeine; Cannabinoids; Electrocardiography; Humans; I | 2014 |
Decreased inward rectifying K+ current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium Channel Blockers; Calcium Signal | 2015 |
Acute effects of Red Bull energy drink on ventricular repolarization in healthy young volunteers: a prospective study.
Topics: Adult; Arrhythmias, Cardiac; Beverages; Caffeine; Electrocardiography; Female; Healthy Volunteers; H | 2015 |
Acute effects of Red Bull energy drink on ventricular repolarization in healthy young volunteers: a prospective study.
Topics: Adult; Arrhythmias, Cardiac; Beverages; Caffeine; Electrocardiography; Female; Healthy Volunteers; H | 2015 |
Acute effects of Red Bull energy drink on ventricular repolarization in healthy young volunteers: a prospective study.
Topics: Adult; Arrhythmias, Cardiac; Beverages; Caffeine; Electrocardiography; Female; Healthy Volunteers; H | 2015 |
Acute effects of Red Bull energy drink on ventricular repolarization in healthy young volunteers: a prospective study.
Topics: Adult; Arrhythmias, Cardiac; Beverages; Caffeine; Electrocardiography; Female; Healthy Volunteers; H | 2015 |
Channel Activity of Cardiac Ryanodine Receptors (RyR2) Determines Potency and Efficacy of Flecainide and R-Propafenone against Arrhythmogenic Calcium Waves in Ventricular Cardiomyocytes.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Signaling; Calsequestrin; Cell Membrane Pe | 2015 |
Electrocardiogram Abnormalities of Caffeine Overdose.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Drug Overdose; Electrocardiography; Female; Humans | 2016 |
Multiple and Concurrent Arrhythmia.
Topics: Arrhythmias, Cardiac; Caffeine; Drug Overdose; Electrocardiography; Humans | 2016 |
The association between pro-arrhythmic agents and aortic stenosis in young adults: is it sufficient to clarify the sudden unexpected deaths?
Topics: Adult; Amitriptyline; Aortic Valve Stenosis; Arrhythmias, Cardiac; Autopsy; Caffeine; Death, Sudden, | 2017 |
Caffeine--watch out for "energy drinks".
Topics: Arrhythmias, Cardiac; Beverages; Caffeine; Chest Pain; Energy Intake; Heart Rate; Humans | 2008 |
Aberration of L-type calcium channel in cardiac myocytes is one of the mechanisms of arrhythmia induced by cerebral ischemia.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Brain Ischemia; Caffeine; Calcium; Calcium Channel | 2008 |
Partial downregulation of junctin enhances cardiac calcium cycling without eliciting ventricular arrhythmias in mice.
Topics: Aging; Animals; Arrhythmias, Cardiac; Caffeine; Calcium Signaling; Calcium-Binding Proteins; Disease | 2009 |
Pharmacological changes in cellular Ca2+ homeostasis parallel initiation of atrial arrhythmogenesis in murine Langendorff-perfused hearts.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Channel Blockers; | 2009 |
Piceatannol, a derivative of resveratrol, moderately slows I(Na) inactivation and exerts antiarrhythmic action in ischaemia-reperfused rat hearts.
Topics: Aconitine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeine; Calci | 2009 |
Intra-sarcoplasmic reticulum Ca2+ oscillations are driven by dynamic regulation of ryanodine receptor function by luminal Ca2+ in cardiomyocytes.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Signaling; Calpain; Calsequestrin; Central | 2009 |
Function of Ca(2+) release channels in Purkinje cells that survive in the infarcted canine heart: a mechanism for triggered Purkinje ectopy.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium Channels; Calcium Signaling; Cell Survival; Disease | 2008 |
Distinguishing properties of cells from the myocardial sleeves of the pulmonary veins: a comparison of normal and abnormal pacemakers.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Biological Clocks; Caffeine; Calcium Signaling; Ca | 2008 |
How to shut down Ca2+-induced Ca2+ release?
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Signaling; Calpain; Calsequestrin; Central | 2009 |
Acute atrial arrhythmogenesis in murine hearts following enhanced extracellular Ca(2+) entry depends on intracellular Ca(2+) stores.
Topics: Aniline Compounds; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium | 2010 |
Transient Ca2+ depletion of the sarcoplasmic reticulum at the onset of reperfusion.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Cytosol; Diastole; Electrocardi | 2010 |
Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia.
Topics: Animals; Arrhythmias, Cardiac; Benzylamines; Blotting, Western; Caffeine; Calcium; Calcium-Calmoduli | 2011 |
Congenital type 1 long QT syndrome unmasked by a highly caffeinated energy drink.
Topics: Adolescent; Arrhythmias, Cardiac; Caffeine; Electrocardiography; Energy Drinks; Female; Humans; Long | 2012 |
[Ephedrine and ephedra in weight loss products and other preparations].
Topics: Adverse Drug Reaction Reporting Systems; Appetite Depressants; Arrhythmias, Cardiac; Caffeine; Centr | 2002 |
[Pathogenic points on experimental arrhythmia from caffein-adrenaline].
Topics: Arrhythmias, Cardiac; Caffeine; Epinephrine; Humans | 1956 |
Cardiac arrhythmias following the use of large doses of central nervous system stimulants.
Topics: Amphetamine; Amphetamines; Arrhythmias, Cardiac; Caffeine; Central Nervous System Stimulants; Humans | 1952 |
Functional heterogeneity of ryanodine receptor mutations associated with sudden cardiac death.
Topics: Arrhythmias, Cardiac; Base Sequence; Caffeine; Calcium; Cell Line; Central Nervous System Stimulants | 2004 |
Caffeine and arrhythmia.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Caffeine; Dose-Response Relationship, Drug; Humans; Risk | 2005 |
Spatial nonuniformity of excitation-contraction coupling causes arrhythmogenic Ca2+ waves in rat cardiac muscle.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Diacetyl; Heart; Myocardial Contraction; Myocytes, | 2005 |
Isoproterenol does not enhance Ca-dependent Na/Ca exchange current in intact rabbit ventricular myocytes.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Cardiotonic Agents; Cells, Cultured; Heart Failure; Heart V | 2005 |
Arrhythmogenic mutation-linked defects in ryanodine receptor autoregulation reveal a novel mechanism of Ca2+ release channel dysfunction.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; CHO Cells; Cricetinae; Death, Sudden, Cardiac; Flu | 2006 |
Comparison of Ca2+-handling properties of canine pulmonary vein and left atrial cardiomyocytes.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Cardiac Pacing, Artificial; Car | 2006 |
Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse model.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Cells, Cultured; Epinephrine; Membrane Potentials; Mice; Mi | 2006 |
Increasing ryanodine receptor open probability alone does not produce arrhythmogenic calcium waves: threshold sarcoplasmic reticulum calcium content is required.
Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Diastole; Differential T | 2007 |
CaM or cAMP: linking beta-adrenergic stimulation to 'leaky' RyRs.
Topics: Animals; Arrhythmias, Cardiac; Binding Sites; Caffeine; Calcium; Calcium Channels, L-Type; Calcium S | 2007 |
Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Cell Line; Cryoelectron Microscopy; Humans; Mice; | 2007 |
Caffeine-activated large-conductance plasma membrane cation channels in cardiac myocytes: characteristics and significance.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium Channel Agonists; Calcium Channel Blockers; Calcium | 2007 |
Sarcoplasmic reticulum Ca2+ release channel ryanodine receptor (RyR2) plays a crucial role in aconitine-induced arrhythmias.
Topics: Aconitine; Animals; Arrhythmias, Cardiac; Caffeine; Calcium Channels, L-Type; Calcium Signaling; Cel | 2008 |
Perturbations in the membrane potential of cultured heart cells: role of calcium.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcimycin; Calcium; Cells, Cultured; Chick Embryo; Diastol | 1984 |
[Calcium antagonists and cardiac arrhythmias in acute ischemia of the myocardium. Experimental data and their clinical implications].
Topics: Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Channel Blockers; Catecholamines; Coronary Disease; | 1984 |
Cardiac arrhythmias after phenylpropanolamine ingestion.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Drug Combinations; Female; Humans; Hypertension; Phenylpropan | 1983 |
Mechanism of caffeine-induced arrhythmias in canine cardiac Purkinje fibers.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Dogs; Dose-Response Relationshi | 1984 |
The arrhythmogenic effects of caffeine in human beings.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Caffeine; Coffee; Electrophysiology; Heart Conduction Syste | 1983 |
Arrhythmogenic effects of caffeine.
Topics: Arrhythmias, Cardiac; Caffeine; Coffee; Humans | 1983 |
Cardiac arrhythmias in an adolescent following ingestion of an over-the-counter stimulant.
Topics: Adolescent; Arrhythmias, Cardiac; Caffeine; Ephedrine; Female; Humans; Nonprescription Drugs; Phenyl | 1982 |
Somatic manifestations of caffeinism.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Central Nervous System Diseases; Diarrhea; Diuresis; Dose-Res | 1981 |
[Treatment of sleep disorders in the elderly].
Topics: Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Caffeine; Cerebrovascular Circulation; Humans; | 1980 |
Caffeine- and aminophylline-induced seizures.
Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Caffeine; Cerebral Cortex; Electrocardiography; Electr | 1981 |
Facilitation of beta-adrenoceptor-mediated slow channel responses by hypoxia in guinea pig ventricular myocardium.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Catecholamines; Electrophysiology; Guine | 1993 |
Caffeine depression of spontaneous activity in rabbit sino-atrial node cells.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Cytoplasm; Depression, Chemical | 1993 |
Chloral hydrate: a dangerous sedative for overdose patients?
Topics: Akathisia, Drug-Induced; Arrhythmias, Cardiac; Caffeine; Child, Preschool; Chloral Hydrate; Contrain | 1994 |
Temperature modulates calcium homeostasis and ventricular arrhythmias in myocardial preparations.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Cell Size; Cold Temperature; Gu | 1994 |
An accidental death related to cocaine, cocaethylene, and caffeine.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Cocaine; Ethanol; Fatal Outcome; Female; Humans; Substance-Re | 1993 |
Positive and negative chronotropic effects of caffeine in spontaneously beating rabbit sino-atrial node cells.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Biological Clocks; Caffeine; Calcium; Heart Rate; | 1993 |
Newborn cardiac arrhythmias associated with maternal caffeine use during pregnancy.
Topics: Arrhythmias, Cardiac; Caffeine; Coffee; Female; Humans; Infant, Newborn; Pregnancy; Prenatal Exposur | 1993 |
Electrophysiological actions of ryanodine on single rabbit sinoatrial nodal cells.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Channels; Drug Synergis | 1997 |
Caffeine ingestion: yet another wake-up call?
Topics: Arrhythmias, Cardiac; Caffeine; Central Nervous System Stimulants; Coffee; Heart Conduction System; | 1998 |
Combined effects of caffeine and alcohol on hemodynamics and coronary artery blood flow in dogs.
Topics: Animals; Arrhythmias, Cardiac; Arteries; Blood Flow Velocity; Caffeine; Central Nervous System Depre | 1999 |
Experimental treatment of the acute cardiovascular toxicity of caffeine.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Aspi | 1999 |
Characterization of a [Ca2+]i-dependent current in human atrial and ventricular cardiomyocytes in the absence of Na+ and K+.
Topics: Aged; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Channels; Cell Separation; Chelating Agents; | 1999 |
Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure.
Topics: Animals; Aortic Valve Insufficiency; Arrhythmias, Cardiac; Caffeine; Calcium; Cardiomegaly; Constric | 1999 |
Inhibition of sarcoplasmic reticulum function by polyunsaturated fatty acids in intact, isolated myocytes from rat ventricular muscle.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Biological Clocks; Biological Transport, Active; C | 2000 |
Sarcoplasmic reticulum Ca content, sarcolemmal Ca influx and the genesis of arrhythmias in isolated guinea-pig cardiomyocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2000 |
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Caffeine; Calc | 2001 |
A laboratory animal model for malignant hyperpyrexia.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Caffeine; Disease Models, Animal; Drug Interactions; Halo | 1979 |
Coffee, caffeine, cholesterol, cardiologists and confusion.
Topics: Arrhythmias, Cardiac; Caffeine; Cholesterol; Coffee; Coronary Disease; Humans; Risk Factors | 1990 |
Sixth International Caffeine Workshop, Hong Kong, 7-10 August 1989.
Topics: Adenosine; Animals; Arrhythmias, Cardiac; Bone Development; Caffeine; DNA Replication; Female; Human | 1990 |
High-dose caffeine and cardiac rate and rhythm in normal subjects.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Cardiac Complexes, Premature; Coffee; Electrocardiography; Fe | 1988 |
Fetal arrhythmia caused by excessive intake of caffeine by pregnant women.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Female; Fetal Blood; Fetal Diseases; Humans; Infant, Newborn; | 1989 |
Ryanodine and caffeine prevent ventricular arrhythmias during acute myocardial ischemia and reperfusion in rat heart.
Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Coronary Circulation; Cyclic AMP; Energ | 1988 |
Caffeine and cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Caffeine; Coffee; Humans; Myocardial Contraction; Tea | 1988 |
Influence of mexiletine on caffeine elimination.
Topics: Adult; Aged; Arrhythmias, Cardiac; Caffeine; Female; Half-Life; Humans; Kinetics; Male; Mexiletine; | 1987 |
[Arrhythmogenic effect of caffeine].
Topics: Arrhythmias, Cardiac; Caffeine; Coffee; Humans | 1986 |
The effect of caffeine on cardiac rate, rhythm, and ventricular repolarization. Analysis of 18 normal subjects and 18 patients with primary ventricular dysrhythmia.
Topics: Adult; Arrhythmias, Cardiac; Caffeine; Electrocardiography; Female; Half-Life; Heart Rate; Heart Ven | 1985 |
[Therapy of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Caffeine; Cardiac Complexes, Prema | 1973 |
Editorial: Calcium responses ("calcium spikes").
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Coronary Disease; Cyclic AMP; E | 1974 |
[Importance of cofee for the organism of an intellectual].
Topics: Arrhythmias, Cardiac; Caffeine; Catecholamines; Coffee; Coronary Circulation; Cyclic AMP; Fatty Acid | 1972 |