caffeine has been researched along with Anxiety in 204 studies
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test if caffeine affects threat-bias, moderated by baseline frontal TBR and trait-anxiety." | 9.27 | Acute effects of caffeine on threat-selective attention: moderation by anxiety and EEG theta/beta ratio. ( Angelidis, A; Putman, P; Schalbroeck, R; van der Does, W; van der Wee, NJA; van Son, D, 2018) |
| "This study aimed to test how expectations and anxiety sensitivity influence respiratory and autonomic responses to caffeine." | 9.20 | Anxiety sensitivity and expectation of arousal differentially affect the respiratory response to caffeine. ( Alius, MG; Blumenthal, T; Hamm, AO; Methling, K; Modeß, C; Pané-Farré, CA, 2015) |
| "This experiment examined the effect of a moderate dose of caffeine on perceptions of leg-muscle pain during a bout of high-intensity cycling exercise and the role of anxiety sensitivity in the hypoalgesic effect of caffeine on muscle pain during exercise." | 9.13 | Effect of caffeine on leg-muscle pain during intense cycling exercise: possible role of anxiety sensitivity. ( Gliottoni, RC; Motl, RW, 2008) |
| "The effects of moderate intensity cycling exercise on the soleus H-reflex and state anxiety were examined among 16 individuals whose anxiety was experimentally manipulated by consumption of a large dose of caffeine." | 9.11 | Effects of acute exercise on the soleus H-reflex and self-reported anxiety after caffeine ingestion. ( Dishman, RK; Motl, RW, 2004) |
| "The current study sought to investigate whether anxiety sensitivity moderates the effect caffeine has on the pain responses of healthy women." | 9.10 | The moderating effect of anxiety sensitivity on caffeine-induced hypoalgesia in healthy women. ( Chaloner, N; Keogh, E, 2002) |
| "The adenosine receptor system, which mediates the psychoactive effects of caffeine, is also thought to be involved in the regulation of anxiety." | 9.10 | Association between A2a receptor gene polymorphisms and caffeine-induced anxiety. ( Alsene, K; de Wit, H; Deckert, J; Sand, P, 2003) |
| "The well-known difficulty in distinguishing the response to a combination headache medication and its individual components in the presence of a high placebo response was again demonstrated in a randomized, double-blind, placebo-controlled, multi-center trial comparing Fiorinal with Codeine and its Fiorinal and codeine phosphate components in relieving the pain, tension, and muscle contraction associated with tension headache." | 9.06 | Fiorinal with Codeine in the management of tension headache: impact of placebo response. ( Friedman, AP; Hwang, DS; Mietlowski, MJ, 1987) |
| "This study investigates whether inhalation of different fractions of lavender essential oil can attenuate the sleep disturbances induced by combined anxiety and caffeine and explores the underlying mechanisms." | 8.31 | Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice. ( Han, T; Liu, F; Ma, L; Wang, W; Xu, Y; Yang, S; Yao, L, 2023) |
| "The present study was designed to investigate the effects of caffeine and adrenaline administration on memory and anxiety in male rats." | 8.12 | Effect Of Caffeine and Adrenaline on Memory and Anxiety in Male Wistar Rats. ( Imam-Fulani, A; Owoyele, BV, 2022) |
| "An increase in brain oxido-nitrosative stress and anxiety-like behavior was observed in caffeine treated mice." | 7.91 | Lacidipine attenuates caffeine-induced anxiety-like symptoms in mice: Role of calcium-induced oxido-nitrosative stress. ( Bansal, N; Khurana, K, 2019) |
| "Anxiety is a common symptom associated with high caffeine intake." | 7.91 | Oxidative Stress Mediates Anxiety-Like Behavior Induced by High Caffeine Intake in Zebrafish: Protective Effect of Alpha-Tocopherol. ( Assad, N; Bahia, CP; Brasil, A; Cardoso, PB; de Carvalho, TS; de Jesus Oliveira Batista, E; Gouveia, A; Herculano, AM; Kauffmann, N; Lima-Bastos, S; Luz, WL; Moraes, S; Oliveira, KRMH; Passos, A; Santos-Silva, M, 2019) |
| " Then at intervals of 3 days, they were administered 1, 2 mg/kg methamphetamine (MA) or saline before being tested for anxiety-related behavior in a zero maze or a light/dark box, or their short-term spatial memory was assessed in a Y maze following introduction of a novel brightness change in one of the arms." | 7.88 | Sex-dependent modification by chronic caffeine of acute methamphetamine effects on anxiety-related behavior in rats. ( Hamilton, JJ; Hughes, RN, 2018) |
| "To assess the possibility that acute caffeine's behavioral action might depend on rats' strain, effects of 50mg/kg of the drug were observed on activity, anxiety-related behavior and habituation learning in male and female rats from three different strains, namely PVG/c, Long-Evans and Wistar." | 7.83 | Strain-dependent effects of acute caffeine on anxiety-related behavior in PVG/c, Long-Evans and Wistar rats. ( Hancock, NJ; Hughes, RN, 2016) |
| "The objective of this study was to determine the effects of different doses of caffeine on appetite and anxiety-related behavior." | 7.83 | Caffeine increases food intake while reducing anxiety-related behaviors. ( Levack, R; Sweeney, P; Watters, J; Xu, Z; Yang, Y, 2016) |
| "To create a match/mismatch of expected and experienced arousal, high and low anxiety sensitive participants received caffeine vs." | 7.81 | Effects of anxiety sensitivity and expectations on the modulation of the startle eyeblink response during a caffeine challenge. ( Benke, C; Blumenthal, TD; Hamm, AO; Modeß, C; Pané-Farré, CA, 2015) |
| "To investigate the role of the melanocortin (MC) system in the framework of the central nucleus of the amygdala (CeA) in the differential effects of the adenosine receptor blocker caffeine on anxiety-like behavior, using the social interaction (SI) test." | 7.80 | Involvement of the central melanocortin system in the effects of caffeine on anxiety-like behavior in mice. ( Bhorkar, AA; Dandekar, MP; Kokare, DM; Nakhate, KT; Subhedar, NK, 2014) |
| "Caffeine is known to improve concentration and reduce fatigue in healthy adults, but high doses may induce anxiety and agitation." | 7.80 | Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study. ( Achterberg, WP; Jongerling, J; Kromhout, MA, 2014) |
| "Caffeine is widely consumed in beverages and food, and its consumption in high doses is associated with anxiety increase." | 7.75 | Sex-specific differences on caffeine consumption and chronic stress-induced anxiety-like behavior and DNA breaks in the hippocampus. ( Andreazza, AC; Arcego, D; Avila, MC; Crema, LM; Dalmaz, C; Diehl, LA; Fachin, A; Gonçalvez, CA; Krolow, R; Noschang, CG; Pettenuzzo, LF; Vendite, D; von Pozzer Toigo, E, 2009) |
| "The aim of this work was to study whether caffeine treatment during brain growth spurt produces long-term effects on the adenosine receptor-regulated behaviors including nociception, anxiety, learning, and memory." | 7.74 | Hyperalgesia, low-anxiety, and impairment of avoidance learning in neonatal caffeine-treated rats. ( Chen, HH; Pan, HZ, 2007) |
| "In the present study, the effect of adenosine (A1 and A2 receptor agonist), caffeine (A2A receptor antagonist), theophylline (A2A receptor antagonist) and their combination was studied in anxiety related behaviours using elevated zero maze and elevated plus maze paradigms and compared their various behavioural profiles." | 7.74 | Involvement of adenosinergic receptors in anxiety related behaviours. ( Bishnoi, M; Kulkarni, SK; Singh, K, 2007) |
| " On the contrary, caffeine produced higher anxiety in animals previously treated with the GABA(A) receptor antagonist, bicuculline or either of the various neurosteroid biosynthesis enzyme inhibitors viz." | 7.73 | Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats. ( Chopde, CT; Hirani, K; Jain, NS, 2005) |
| "1% caffeine as a single source of fluid on anxiety in rats with different anxiety level (either genetically determined or individually acquired) was studied." | 7.71 | Effect of short-term and chronic caffeine intake on rats with various anxiety level. ( Figurina, IB; Medvedeva, OF; Rusakova, IV; Sudakov, SK, 2001) |
| "Caffeine acutely administered (50 or 100 mg/kg IP) induced anxiety-like effects in both procedures." | 7.70 | The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists. ( Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM, 2000) |
| "The concentration of kynurenine, a neuroactive tryptophan metabolite, in blood plasma after pharmacologically induced anxiety was studied." | 7.68 | Caffeine-induced anxiety and increase of kynurenine concentration in plasma of healthy subjects: a pilot study. ( Orlikov, A; Ryzov, I, 1991) |
| "The effect of a combination of caffeine and yohimbine was investigated in the social interaction, elevated plus-maze and punished-drinking tests of anxiety." | 7.67 | Antagonistic effects of caffeine and yohimbine in animal tests of anxiety. ( Baldwin, HA; File, SE; Johnston, AL, 1989) |
| "A review of the recent literature shows the role of caffeine in the physiology, mood, and behavior of persons to be a complex one including changes in arousal, anxiety, and performance." | 7.66 | Caffeine and human behavior: arousal, anxiety, and performance effects. ( Julia, HL; Sawyer, DA; Turin, AC, 1982) |
| " However, long-term administration of this approach is linked to several complications, and a definitive gold-standard therapy for PD is yet to be identified." | 5.91 | Caffeine alleviates anxiety-like behavior and brainstem lesions in a rotenone-induced rat model of Parkinson's disease. ( Adeyeye, TA; Babatunde, BR; Ehireme, SE; Shallie, PD, 2023) |
| "Caffeine is a central nervous system stimulant and acts in the brain through adenosine receptors, influencing attention, alertness, and anxiety." | 5.72 | Caffeine-related genes influence anxiety disorders in children and adults with ADHD. ( Bandeira, CE; Bau, CHD; Contini, V; da Silva, BS; Dresch, F; Fraporti, TT; Genro, JP; Grevet, EH; Hutz, MH; Martins-Silva, T; Rohde, LA; Rovaris, DL; Tovo-Rodrigues, L, 2022) |
| "Caffeine was administrated during all prenatal and postnatal life (CAF, 0." | 5.51 | Lifelong exposure to caffeine increases anxiety-like behavior in adult mice exposed to tobacco smoke during adolescence. ( Abreu-Villaça, Y; da Silva Gonçalves, B; Filgueiras, CC; Leal-Rocha, PH; Manhães, AC; Ribeiro-Carvalho, A, 2019) |
| "We assessed the seizure vulnerability and anxiety responses following the chronic co-administration of, and withdrawal from, caffeine and ethanol in male rats." | 5.48 | Seizure vulnerability and anxiety responses following chronic co-administration and acute withdrawal of caffeine and ethanol in a rat model. ( Alele, PE; Matovu, D, 2018) |
| "Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation." | 5.48 | Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018) |
| "Caffeine consumption has been increasing rapidly in adolescents; however, most research on the behavioral effects of caffeine has been conducted in adults." | 5.43 | Chronic caffeine produces sexually dimorphic effects on amphetamine-induced behavior, anxiety and depressive-like behavior in adolescent rats. ( Dixon, RS; Hickman, ET; Lee, SM; Townsend, SE; Turgeon, SM, 2016) |
| "Caffeine is a commonly used psychoactive substance and consumption by children and adolescents continues to rise." | 5.43 | Adolescent caffeine consumption increases adulthood anxiety-related behavior and modifies neuroendocrine signaling. ( Archuleta, S; Bachtell, RK; Campeau, S; Levis, SC; Newsom, RJ; O'Neill, CE; Scott, T; Spencer, RL; Stafford, J, 2016) |
| "Furthermore, caffeine treatment during pregnancy and lactation causes long-term behavioral changes in the mice offspring that manifest later in life." | 5.43 | Behavioral profile assessment in offspring of Swiss mice treated during pregnancy and lactation with caffeine. ( Côrtes, Wda S; da Conceição, RR; da Rocha, FF; da Silva-Almeida, C; da Silveira, AL; de Azevedo Cruz Seara, F; Laureano-Melo, R; Marinho, BG; Reis, LC, 2016) |
| " The drug combination led to more male ambulation than for alcohol alone, and higher occupancy of the center squares of the apparatus than for males in any other group." | 5.37 | Adult anxiety-related behavior of rats following consumption during late adolescence of alcohol alone and in combination with caffeine. ( Hughes, RN, 2011) |
| "Depression was positively related to caffeine use for both cohorts, though mediated by caffeine withdrawal effects." | 5.35 | Mountain Dew or mountain don't?: a pilot investigation of caffeine use parameters and relations to depression and anxiety symptoms in 5th- and 10th-grade students. ( Bell, DJ; Luebbe, AM, 2009) |
| "Caffeine may produce symptoms of anxiety-nervousness without increasing central norepinephrine turnover." | 5.27 | The effects of caffeine on plasma MHPG, subjective anxiety, autonomic symptoms and blood pressure in healthy humans. ( Charney, DS; Galloway, MP; Heninger, GR, 1984) |
| " Zebrafish models of stress establish that both caffeine and ethanol influence anxiety, though few studies have implemented coadministration to assess the interaction of anxiety and reward-seeking." | 5.22 | Neurochemical and Behavioral Consequences of Ethanol and/or Caffeine Exposure: Effects in Zebrafish and Rodents. ( Clayman, CL; Connaughton, VP, 2022) |
| "While caffeine benefits motor performance and tolerance develops to its tendency to increase anxiety/jitteriness, tolerance to its effects on sleepiness means that frequent consumption fails to enhance mental alertness and mental performance." | 5.17 | Faster but not smarter: effects of caffeine and caffeine withdrawal on alertness and performance. ( Heatherley, SV; Mullings, EL; Rogers, PJ; Smith, JE, 2013) |
| "This experiment examined the effect of a moderate dose of caffeine on perceptions of leg-muscle pain during a bout of high-intensity cycling exercise and the role of anxiety sensitivity in the hypoalgesic effect of caffeine on muscle pain during exercise." | 5.13 | Effect of caffeine on leg-muscle pain during intense cycling exercise: possible role of anxiety sensitivity. ( Gliottoni, RC; Motl, RW, 2008) |
| "The adenosine receptor system, which mediates the psychoactive effects of caffeine, is also thought to be involved in the regulation of anxiety." | 5.10 | Association between A2a receptor gene polymorphisms and caffeine-induced anxiety. ( Alsene, K; de Wit, H; Deckert, J; Sand, P, 2003) |
| "Abstinence from smoking increases blood levels of caffeine and may potentiate the ability of caffeine to increase anxiety, insomnia, etc." | 5.09 | Effect of smoking abstinence on the subjective effects of caffeine. ( Dominick, A; Hughes, JR; Liguori, A; MacLaughlin, M, 1999) |
| "The well-known difficulty in distinguishing the response to a combination headache medication and its individual components in the presence of a high placebo response was again demonstrated in a randomized, double-blind, placebo-controlled, multi-center trial comparing Fiorinal with Codeine and its Fiorinal and codeine phosphate components in relieving the pain, tension, and muscle contraction associated with tension headache." | 5.06 | Fiorinal with Codeine in the management of tension headache: impact of placebo response. ( Friedman, AP; Hwang, DS; Mietlowski, MJ, 1987) |
| "This report evaluates the scientific literature on caffeine with respect to potential central nervous system (CNS) effects, specifically effects on sleep, anxiety, and aggression/risk-taking." | 4.93 | Neurobehavioral hazard identification and characterization for caffeine. ( Mariano, GF; Rodricks, JV; Turnbull, D, 2016) |
| "When administered to normal healthy patients, a nonselective adenosine A1/A2A antagonist, caffeine, tended to improve anxiety and depression at low doses and to exacerbate anxiety at high doses." | 4.90 | Involvement of adenosine A2A receptors in depression and anxiety. ( Kanda, T; Kobayashi, M; Yamada, K, 2014) |
| " However, caffeine at high doses can increase anxiety, insomnia, calcium loss and possibly the risk of fractures." | 4.89 | Coffee and tea: perks for health and longevity? ( Bhatti, SK; Lavie, CJ; O'Keefe, JH, 2013) |
| "Chronic, heavy caffeine ingestion may cause or exacerbate anxiety and may be associated with depression and increased use of antianxiety drugs." | 4.77 | Psychotropic effects of caffeine. ( Clementz, GL; Dailey, JW, 1988) |
| "This study investigates whether inhalation of different fractions of lavender essential oil can attenuate the sleep disturbances induced by combined anxiety and caffeine and explores the underlying mechanisms." | 4.31 | Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice. ( Han, T; Liu, F; Ma, L; Wang, W; Xu, Y; Yang, S; Yao, L, 2023) |
| " To seek RNAs involved in the anxiety disorder-metabolic disorder link, we subjected zebrafish larvae to caffeine-induced anxiety or high-fat diet (HFD)-induced obesity followed by RNA sequencing and analyses." | 4.31 | Inversely Regulated Inflammation-Related Processes Mediate Anxiety-Obesity Links in Zebrafish Larvae and Adults. ( Goldberg, D; Madrer, N; Meerson, A; Soreq, H; Yehuda, H, 2023) |
| " We validated this as anxiety-like behaviors with diazepam reducing, and caffeine increasing the time spent in the bottom of the novel environment." | 4.12 | The larval diving response (LDR): Validation of an automated, high-throughput, ecologically relevant measure of anxiety-related behavior in larval zebrafish (Danio rerio). ( Fontana, BD; Parker, MO, 2022) |
| "An increase in brain oxido-nitrosative stress and anxiety-like behavior was observed in caffeine treated mice." | 3.91 | Lacidipine attenuates caffeine-induced anxiety-like symptoms in mice: Role of calcium-induced oxido-nitrosative stress. ( Bansal, N; Khurana, K, 2019) |
| "Anxiety is a common symptom associated with high caffeine intake." | 3.91 | Oxidative Stress Mediates Anxiety-Like Behavior Induced by High Caffeine Intake in Zebrafish: Protective Effect of Alpha-Tocopherol. ( Assad, N; Bahia, CP; Brasil, A; Cardoso, PB; de Carvalho, TS; de Jesus Oliveira Batista, E; Gouveia, A; Herculano, AM; Kauffmann, N; Lima-Bastos, S; Luz, WL; Moraes, S; Oliveira, KRMH; Passos, A; Santos-Silva, M, 2019) |
| "The objective of this study was to determine the effects of different doses of caffeine on appetite and anxiety-related behavior." | 3.83 | Caffeine increases food intake while reducing anxiety-related behaviors. ( Levack, R; Sweeney, P; Watters, J; Xu, Z; Yang, Y, 2016) |
| "To create a match/mismatch of expected and experienced arousal, high and low anxiety sensitive participants received caffeine vs." | 3.81 | Effects of anxiety sensitivity and expectations on the modulation of the startle eyeblink response during a caffeine challenge. ( Benke, C; Blumenthal, TD; Hamm, AO; Modeß, C; Pané-Farré, CA, 2015) |
| "Caffeine is known to improve concentration and reduce fatigue in healthy adults, but high doses may induce anxiety and agitation." | 3.80 | Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study. ( Achterberg, WP; Jongerling, J; Kromhout, MA, 2014) |
| "Adenosinergic systems have been implicated in anxiety-like states, as caffeine can induce a state of anxiety in human beings." | 3.77 | Adenosine A1, but not A2, receptor blockade increases anxiety and arousal in Zebrafish. ( Herculano, AM; Lima, MG; Maximino, C; Olivera, KR; Picanço-Diniz, DL, 2011) |
| "Caffeine is widely consumed in beverages and food, and its consumption in high doses is associated with anxiety increase." | 3.75 | Sex-specific differences on caffeine consumption and chronic stress-induced anxiety-like behavior and DNA breaks in the hippocampus. ( Andreazza, AC; Arcego, D; Avila, MC; Crema, LM; Dalmaz, C; Diehl, LA; Fachin, A; Gonçalvez, CA; Krolow, R; Noschang, CG; Pettenuzzo, LF; Vendite, D; von Pozzer Toigo, E, 2009) |
| "The aim of this work was to study whether caffeine treatment during brain growth spurt produces long-term effects on the adenosine receptor-regulated behaviors including nociception, anxiety, learning, and memory." | 3.74 | Hyperalgesia, low-anxiety, and impairment of avoidance learning in neonatal caffeine-treated rats. ( Chen, HH; Pan, HZ, 2007) |
| "In the present study, the effect of adenosine (A1 and A2 receptor agonist), caffeine (A2A receptor antagonist), theophylline (A2A receptor antagonist) and their combination was studied in anxiety related behaviours using elevated zero maze and elevated plus maze paradigms and compared their various behavioural profiles." | 3.74 | Involvement of adenosinergic receptors in anxiety related behaviours. ( Bishnoi, M; Kulkarni, SK; Singh, K, 2007) |
| " Self-medication for pain or common cold symptoms was reported by 54% while 8% had taken caffeine tablets or other stimulants." | 3.73 | Self-medication among Finnish young men in the beginning of common military service. ( Jormanainen, V; Linden, K; Pietilä, K; Swigonski, NL, 2005) |
| " On the contrary, caffeine produced higher anxiety in animals previously treated with the GABA(A) receptor antagonist, bicuculline or either of the various neurosteroid biosynthesis enzyme inhibitors viz." | 3.73 | Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats. ( Chopde, CT; Hirani, K; Jain, NS, 2005) |
| "We used Fos immunocytochemistry to test the effects of four anxiogenic drugs (FG-7142, yohimbine, m-chlorophenylpiperazine [mCPP], and caffeine) on anxiety-related circuitry in rat forebrain." | 3.72 | Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs. ( Salchner, P; Sharp, T; Singewald, N, 2003) |
| "This experiment examined the influence of acute exercise on anxiety following caffeine-induced elevations in self-rated anxiety." | 3.70 | Acute exercise reduces caffeine-induced anxiogenesis. ( Crabbe, JB; Dishman, RK; O'Connor, PJ; Youngstedt, SD, 1998) |
| "), an endogenous neuroactive metabolite of tryptophan, attenuated the most stable effect of anxiogens in this model of anxiety--a decrease in the rate of leanings-out of the dark compartment --induced by caffeine, pentylenetetrazole and yohimbine, but not by beta-phenylethylamine (PEA)." | 3.70 | Antagonism of kynurenic acid to anxiogens in mice. ( Lapin, IP, 1998) |
| "Nine heavy caffeine users and nine caffeine-intolerant individuals, who had previously discontinued or substantially curtailed use of caffeinated products because of associated anxiety and discomforting physiological arousal, were studied at baseline and then during 1 hour following ingestion of caffeine citrate (10 mg/kg)." | 3.70 | Human brain metabolic response to caffeine and the effects of tolerance. ( Artru, AA; Dager, SR; Friedman, SD; Hayes, CE; Heide, A; Layton, ME; Posse, S; Richards, TL; Strauss, W, 1999) |
| "The present study extended the previous studies to determine the effects of acute and repeated administration of caffeine, a non-specific phosphodiesterase (PDE) inhibitor and pentoxyfylline, a specific type-4 phosphodiesterase (PDE4) inhibitor on (1) baseline anxiety-like behavior and (2) the response to an acute challenge with diazepam on anxiety-like behavior in the hole-board test." | 3.70 | Effects of acute and repeated dose administration of caffeine and pentoxifylline on diazepam-induced mouse behavior in the hole-board test. ( Campos, AR; Paula, WG; Rao, VS; Santos, FA; Silva, RM, 1999) |
| "Caffeine acutely administered (50 or 100 mg/kg IP) induced anxiety-like effects in both procedures." | 3.70 | The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists. ( Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM, 2000) |
| " Helping the client alter her caffeine intake and dietary habits led to a significant reduction in panic attacks, but had less impact on her anxiety levels and sense of control." | 3.69 | Somatic sensations, anxiety, and control in panic disorder. ( Berenbaum, H; Salzer, MS, 1994) |
| "In view of a possible role of kynurenine in caffeine-induced anxiety syndrome, the effects of single and repeated administration of caffeine on hepatic tryptophan (T)-pyrrolase activity are investigated." | 3.69 | Enhancement of hepatic tryptophan pyrrolase activity and decreases of open field locomotion following single and repeated administration of high doses of caffeine in rats. ( Haleem, DJ; Parveen, T; Yasmeen, A; Zafar, A, 1994) |
| "The effects of the anxiogenic agents FG7142, caffeine, pentylenetetrazole, and amphetamine were assessed in two anxiety situations in the marmoset, first in an "anxiogenic" test based on the animal's response to a human observer standing in front of the home cage and second in a low-anxiety situation where animals behaviour was videotaped in the absence of the observer." | 3.68 | Behavioural effects of anxiogenic agents in the common marmoset. ( Carey, GJ; Costall, B; Domeney, AM; Jones, DN; Naylor, RJ, 1992) |
| " In order to provide additional evidence, all eight patients had vastus lateralis muscle biopsies with subsequent caffeine-halothane contracture studies performed." | 3.68 | Malignant hyperthermia in the otolaryngologic patient: prospective anesthetic and surgical management of eight children. ( Dubrow, TJ; Dudley, JP; Reynolds, R, 1990) |
| "The purpose of this study was to determine the mechanism by which caffeine increases anxiety." | 3.67 | Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors. ( Baldwin, HA; File, SE, 1989) |
| "A review of the recent literature shows the role of caffeine in the physiology, mood, and behavior of persons to be a complex one including changes in arousal, anxiety, and performance." | 3.66 | Caffeine and human behavior: arousal, anxiety, and performance effects. ( Julia, HL; Sawyer, DA; Turin, AC, 1982) |
| "The authors explored the relationship between ad lib caffeine consumption in college students and the incidence of caffeinism, characterized by heightened anxiety, depression, and various psychophysiological reactions." | 3.66 | Ad lib caffeine consumption, symptoms of caffeinism, and academic performance. ( Andress, D; Gilliland, K, 1981) |
| "Among 83 hospitalized adult psychiatric patients, 22% reported being high caffeine consumers (750 mg or more per day); these patients scored significantly greater on the State-Trait Anxiety Index and the Beck Depression Scale than moderate and low consumers." | 3.66 | Anxiety and depression associated with caffeinism among psychiatric inpatients. ( Chamberlin, K; Fontaine, P; Greden, JF; Lubetsky, M, 1978) |
| "This clinical study of 62 patients with restless legs syndrome and associated anxious-depressed and other clinical states seems to indicate that caffeine is the major etiological factor in the causation of the restless legs syndrome." | 3.66 | Restless legs, anxiety and caffeinism. ( Lutz, EG, 1978) |
| "Drugs that reduce anxiety may be mediated by cyclic adenosine monophosphate in the brain because (i) potent anxiety-reducing drugs are also potent inhibitors of brain phosphodiesterase activity; (ii) dibutyryl cyclic adenosine monophosphate has the ability to reduce anxiety; (iii) the methylxanthines show significant anxiety-reducing effects; (iv) theophylline and chlordiazepoxide produce additive anxiety-reducing activity; and (v) there is a significant correlation between the anxiety-reducing property of drugs and their ability to inhibit phosphodiesterase activity in the brain." | 3.65 | Cyclic adenosine monophosphate phosphodiesterase in brain: effect on anxiety. ( Beer, B; Chasin, M; Clody, DE; Vogel, JR, 1972) |
| " The ingestion of low to moderate doses of caffeinated energy drinks has been associated with adverse side effects such as insomnia or increased nervousness." | 2.79 | The use of energy drinks in sport: perceived ergogenicity and side effects in male and female athletes. ( Abian-Vicen, J; Areces, F; Del Coso, J; Gallo-Salazar, C; Gonzalez-Millán, C; Lara, B; Ruiz-Vicente, D; Salinero, JJ, 2014) |
| "Caffeine did not increase alertness in NL participants." | 2.75 | Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption. ( Deckert, J; Evershed, RP; Heatherley, SV; Hohoff, C; Maxfield, PJ; Mullings, EL; Nutt, DJ; Rogers, PJ, 2010) |
| "3." | 2.72 | International society of sports nutrition position stand: caffeine and exercise performance. ( Antonio, J; Arent, SM; Campbell, BI; Goldstein, ER; Grgic, J; Guest, NS; Jenkins, NDM; Kalman, DS; Nelson, MT; Schoenfeld, BJ; Smith-Ryan, AE; Stout, JR; Trexler, ET; VanDusseldorp, TA, 2021) |
| "Caffeine was administrated to human subjects in within-subjects designs (n = 24 and n = 18)." | 2.69 | Caffeine and prepulse inhibition of the acoustic startle reflex. ( Elden, A; Flaten, MA, 1999) |
| "Caffeine produced an increase in self-reported muscular tension and tended to increase anxiety and delta magnitude." | 2.68 | Caffeine and smoking: subjective, performance, and psychophysiological effects. ( Davis, RA; deBethizy, JD; Pritchard, WS; Robinson, JH; Stiles, MF, 1995) |
| "Caffeine did not increase cocaine-like effect or desire-for-cocaine ratings among the FCD subjects." | 2.68 | Subjective effects of oral caffeine in formerly cocaine-dependent humans. ( Callas, P; Goldberg, K; Hughes, JR; Liguori, A, 1997) |
| "Caffeine can cause anxiety symptoms in normal individuals, especially in vulnerable patients, like those with pre-existing anxiety disorders." | 2.42 | Caffeine and psychiatric symptoms: a review. ( Benjamin, AB; Broderick, P, 2004) |
| " Our results indicated that chronic administration of nandrolone decanoate (10 mg/kg, i." | 1.91 | Adenosine receptors participate in anabolic-androgenic steroid-induced changes on risk assessment/anxiety-like behaviors in male and female rats. ( Dos Santos-Rodrigues, A; Jardim-Messeder, D; Pandolfo, P; Penna, DBS; Raony, Í, 2023) |
| " However, long-term administration of this approach is linked to several complications, and a definitive gold-standard therapy for PD is yet to be identified." | 1.91 | Caffeine alleviates anxiety-like behavior and brainstem lesions in a rotenone-induced rat model of Parkinson's disease. ( Adeyeye, TA; Babatunde, BR; Ehireme, SE; Shallie, PD, 2023) |
| "Generalized anxiety disorder and major depressive disorder often benefit from medication and psychotherapy." | 1.91 | Relationship between Baseline Physical Activity and Generalized Anxiety Disorder and Major Depressive Disorder Treatment Outcomes. ( Benitah Bulbarelli, EM; Chauhan, M; Clapp, AD; Ismaeel, O; Niazi, SK; Nishi, LM; Pujalte, GGA; Shahsamand, A; Yazeji, J, 2023) |
| "Caffeine is a central nervous system stimulant and acts in the brain through adenosine receptors, influencing attention, alertness, and anxiety." | 1.72 | Caffeine-related genes influence anxiety disorders in children and adults with ADHD. ( Bandeira, CE; Bau, CHD; Contini, V; da Silva, BS; Dresch, F; Fraporti, TT; Genro, JP; Grevet, EH; Hutz, MH; Martins-Silva, T; Rohde, LA; Rovaris, DL; Tovo-Rodrigues, L, 2022) |
| "Caffeine is a commonly used stimulant of the central nervous system that reduces fatigue, increases alertness, and exerts positive effects on emotion through actions on various brain structures." | 1.62 | Estrous cycle modulates the anxiogenic effects of caffeine in the elevated plus maze and light/dark box in female rats. ( Cueto-Escobedo, J; Guillén-Ruiz, G; Hernández-López, F; Herrera-Huerta, EV; Rivera-Aburto, LE; Rodríguez-Landa, JF, 2021) |
| "Caffeine-treated adolescent male rats were exposed to caffeine (0." | 1.56 | Pharmacological depletion of serotonin and norepinephrine with para-chlorophenylalanine and alpha-methyl-p-tyrosine reverses the antidepressant-like effects of adolescent caffeine exposure in the male rat. ( Abdulzahir, A; Hwang, K; Sanford, J; Turgeon, SM, 2020) |
| "Caffeine was administrated during all prenatal and postnatal life (CAF, 0." | 1.51 | Lifelong exposure to caffeine increases anxiety-like behavior in adult mice exposed to tobacco smoke during adolescence. ( Abreu-Villaça, Y; da Silva Gonçalves, B; Filgueiras, CC; Leal-Rocha, PH; Manhães, AC; Ribeiro-Carvalho, A, 2019) |
| "We assessed the seizure vulnerability and anxiety responses following the chronic co-administration of, and withdrawal from, caffeine and ethanol in male rats." | 1.48 | Seizure vulnerability and anxiety responses following chronic co-administration and acute withdrawal of caffeine and ethanol in a rat model. ( Alele, PE; Matovu, D, 2018) |
| "Caffeine is a substance present in several foods and drinks of common western diet." | 1.48 | Different effects of caffeine on behavioral neurophenotypes of two zebrafish populations. ( Ardais, AP; Costa, FV; Fontana, BD; Porciúncula, LO; Quadros, VA; Rosa, LV; Rosemberg, DB, 2018) |
| "Ephedrine alkaloids-free Ephedra Herb extract (EFE) has been developed to eliminate the adverse effects caused by ephedrine alkaloid-induced sympathetic hyperactivation." | 1.48 | Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias. ( Amakura, Y; Goda, Y; Hakamatsuka, T; Hanawa, T; Hyuga, M; Hyuga, S; Kobayashi, Y; Maruyama, T; Odaguchi, H; Oshima, N; Takahashi, J; Takemoto, H; Uchiyama, N; Yamashita, T, 2018) |
| "Caffeine in both treatment regimens caused hyperlocomotion only in male rats, whereas anxiety-related behavior was attenuated in both sexes by caffeine (1." | 1.43 | Caffeine exposure during rat brain development causes memory impairment in a sex selective manner that is offset by caffeine consumption throughout life. ( Ardais, AP; Borges, MF; Botton, PH; Cunha, RA; Fioreze, GT; Mioranzza, S; Nunes, F; Pagnussat, N; Porciúncula, Lde O; Rocha, AS; Sallaberry, C, 2016) |
| "Caffeine consumption has been increasing rapidly in adolescents; however, most research on the behavioral effects of caffeine has been conducted in adults." | 1.43 | Chronic caffeine produces sexually dimorphic effects on amphetamine-induced behavior, anxiety and depressive-like behavior in adolescent rats. ( Dixon, RS; Hickman, ET; Lee, SM; Townsend, SE; Turgeon, SM, 2016) |
| "Caffeine is a commonly used psychoactive substance and consumption by children and adolescents continues to rise." | 1.43 | Adolescent caffeine consumption increases adulthood anxiety-related behavior and modifies neuroendocrine signaling. ( Archuleta, S; Bachtell, RK; Campeau, S; Levis, SC; Newsom, RJ; O'Neill, CE; Scott, T; Spencer, RL; Stafford, J, 2016) |
| "Furthermore, caffeine treatment during pregnancy and lactation causes long-term behavioral changes in the mice offspring that manifest later in life." | 1.43 | Behavioral profile assessment in offspring of Swiss mice treated during pregnancy and lactation with caffeine. ( Côrtes, Wda S; da Conceição, RR; da Rocha, FF; da Silva-Almeida, C; da Silveira, AL; de Azevedo Cruz Seara, F; Laureano-Melo, R; Marinho, BG; Reis, LC, 2016) |
| " One such case describes a caffeine-naïve service member who suffered an adverse reaction after taking an allegedly moderate dose of caffeine from a pill he obtained from a teammate." | 1.42 | Caffeine Toxicity Due to Supplement Use in Caffeine--Naïve Individual: A Cautionary Tale. ( Leggit, JC; Lystrup, RM, 2015) |
| "Caffeine treatment (5 mg/kg/day) began when animals were ≈4 months old, and lasted for 6 months." | 1.38 | Chronic caffeine consumption prevents cognitive decline from young to middle age in rats, and is associated with increased length, branching, and spine density of basal dendrites in CA1 hippocampal neurons. ( Alvarez-Cervera, FJ; Arankowsky-Sandoval, G; Bata-García, JL; Cabrera-Isidoro, S; Flores, G; Góngora-Alfaro, JL; Heredia-López, F; Juárez-Díaz, I; Vila-Luna, L; Vila-Luna, S; Zapata-Vázquez, RE, 2012) |
| "Caffeine treatment seekers (mean age 41 years, 55% women) consumed an average of 548 mg caffeine per day." | 1.38 | Characterization of individuals seeking treatment for caffeine dependence. ( Evatt, DP; Griffiths, RR; Juliano, LM; Richards, BD, 2012) |
| "Diazepam was anxiolytic in males but not females." | 1.37 | Anxiolytic and anxiogenic drug effects on male and female gerbils in the black-white box. ( Bradley, BF; Bridges, NJ; Brown, SL; Lea, RW; Starkey, NJ, 2011) |
| " The benzodiazepines produced a hormetic (inverted U-shaped) dose-response profile, with intermediate doses producing anxiolysis and no effect at higher doses; clonazepam, a high-potency benzodiazepine agonist, produced a locomotor impairment at the highest dose." | 1.37 | Pharmacological analysis of zebrafish (Danio rerio) scototaxis. ( da Silva, AW; Gouveia, A; Herculano, AM; Maximino, C, 2011) |
| "Caffeine (10 mg/kg) pretreatment with venlfaxine (5 mg/kg) did not produce any significant effect on locomotor activity, immobility period and oxidative damage as compared to their effect per se." | 1.36 | Venlafaxine involves nitric oxide modulatory mechanism in experimental model of chronic behavior despair in mice. ( Garg, R; Gaur, V; Kumar, A; Kumar, P, 2010) |
| "A 2 x 2 (Worry x Induced sleeplessness) analysis of covariance design was used." | 1.34 | Night-time thoughts in high and low worriers: reaction to caffeine-induced sleeplessness. ( Bjorvatn, B; Nordhus, IH; Omvik, S; Pallesen, S; Thayer, J, 2007) |
| "Caffeine has reinforcing and anxiogenic properties." | 1.33 | Preference for caffeine appears earlier in non-anxious than in anxious mice. ( Costentin, J; Pelloux, Y; Vautrin, S, 2005) |
| "Caffeine treatment at the dose 10 mg/kg b." | 1.28 | Validation of aversion towards open space and height as a measure of anxiety in the genetically based animal model of depression. ( Golda, V; Petr, R, 1990) |
| "Caffeine may produce symptoms of anxiety-nervousness without increasing central norepinephrine turnover." | 1.27 | The effects of caffeine on plasma MHPG, subjective anxiety, autonomic symptoms and blood pressure in healthy humans. ( Charney, DS; Galloway, MP; Heninger, GR, 1984) |
| " The stimulant effects consisted in delayed intrasession habituation, and they differed in magnitude according to dosage and the complexity of the tunnel arrangements." | 1.27 | Effects of tunnel maze complexity on caffeinic hyperactivity in the rat. ( Bättig, K; Martin, JR; Oettinger, R; Rosenberg, E, 1985) |
| " Chronic administration dissociated the pattern of results produced by sodium phenobarbitone (35 mg/kg) from that produced by flurazepam (0." | 1.26 | A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants. ( File, SE; Hyde, JR, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (18.63) | 18.7374 |
| 1990's | 30 (14.71) | 18.2507 |
| 2000's | 38 (18.63) | 29.6817 |
| 2010's | 74 (36.27) | 24.3611 |
| 2020's | 24 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Clayman, CL | 1 |
| Connaughton, VP | 1 |
| Fraporti, TT | 1 |
| Bandeira, CE | 1 |
| Tovo-Rodrigues, L | 1 |
| Martins-Silva, T | 1 |
| Hutz, MH | 1 |
| Rohde, LA | 1 |
| Bau, CHD | 1 |
| Grevet, EH | 1 |
| da Silva, BS | 1 |
| Rovaris, DL | 1 |
| Dresch, F | 1 |
| Contini, V | 1 |
| Genro, JP | 1 |
| Paz-Graniel, I | 1 |
| Kose, J | 1 |
| Babio, N | 1 |
| Hercberg, S | 1 |
| Galan, P | 1 |
| Touvier, M | 1 |
| Salas-Salvadó, J | 1 |
| Andreeva, VA | 1 |
| Imam-Fulani, A | 1 |
| Owoyele, BV | 1 |
| Fontana, BD | 2 |
| Parker, MO | 1 |
| Yoshida, M | 1 |
| Xu, Y | 1 |
| Ma, L | 1 |
| Liu, F | 1 |
| Yao, L | 1 |
| Wang, W | 1 |
| Yang, S | 1 |
| Han, T | 1 |
| Penna, DBS | 1 |
| Raony, Í | 1 |
| Jardim-Messeder, D | 1 |
| Dos Santos-Rodrigues, A | 1 |
| Pandolfo, P | 1 |
| Adcock, S | 1 |
| Lang, B | 1 |
| Dutra-Tavares, AC | 1 |
| Ribeiro-Carvalho, A | 2 |
| Nunes, F | 3 |
| Araújo, UC | 1 |
| Bruno, V | 1 |
| Marcourakis, T | 1 |
| Filgueiras, CC | 2 |
| Manhães, AC | 2 |
| Abreu-Villaça, Y | 2 |
| Amar, A | 1 |
| Ramachandran, B | 1 |
| Florén Lind, S | 2 |
| Stam, F | 2 |
| Zelleroth, S | 2 |
| Meurling, E | 1 |
| Frick, A | 2 |
| Grönbladh, A | 2 |
| Yehuda, H | 1 |
| Madrer, N | 1 |
| Goldberg, D | 1 |
| Soreq, H | 1 |
| Meerson, A | 1 |
| Adeyeye, TA | 1 |
| Babatunde, BR | 1 |
| Ehireme, SE | 1 |
| Shallie, PD | 1 |
| Atila, O | 1 |
| Deniz, E | 1 |
| Ari, A | 1 |
| Sengur, A | 1 |
| Chakraborty, S | 1 |
| Barua, PD | 1 |
| Acharya, UR | 1 |
| Clapp, AD | 1 |
| Pujalte, GGA | 1 |
| Nishi, LM | 1 |
| Benitah Bulbarelli, EM | 1 |
| Yazeji, J | 1 |
| Shahsamand, A | 1 |
| Niazi, SK | 1 |
| Ismaeel, O | 1 |
| Chauhan, M | 1 |
| Burbano-L, DA | 1 |
| Porfiri, M | 2 |
| Khurana, K | 1 |
| Bansal, N | 1 |
| de Carvalho, TS | 1 |
| Cardoso, PB | 1 |
| Santos-Silva, M | 1 |
| Lima-Bastos, S | 1 |
| Luz, WL | 1 |
| Assad, N | 1 |
| Kauffmann, N | 1 |
| Passos, A | 1 |
| Brasil, A | 1 |
| Bahia, CP | 1 |
| Moraes, S | 1 |
| Gouveia, A | 3 |
| de Jesus Oliveira Batista, E | 1 |
| Oliveira, KRMH | 1 |
| Herculano, AM | 4 |
| Rosa, LV | 2 |
| Costa, FV | 2 |
| Canzian, J | 1 |
| Borba, JV | 1 |
| Quadros, VA | 2 |
| Rosemberg, DB | 2 |
| Mitra, S | 1 |
| Santana Miranda, V | 1 |
| McMillan, C | 1 |
| Dykes, D | 1 |
| Mucha, M | 1 |
| Marth, TE | 1 |
| Poe, B | 1 |
| Basu, DG | 1 |
| Bult-Ito, A | 1 |
| Turgeon, SM | 3 |
| Abdulzahir, A | 1 |
| Hwang, K | 1 |
| Sanford, J | 1 |
| Guest, NS | 1 |
| VanDusseldorp, TA | 1 |
| Nelson, MT | 1 |
| Grgic, J | 1 |
| Schoenfeld, BJ | 1 |
| Jenkins, NDM | 1 |
| Arent, SM | 1 |
| Antonio, J | 1 |
| Stout, JR | 1 |
| Trexler, ET | 1 |
| Smith-Ryan, AE | 1 |
| Goldstein, ER | 1 |
| Kalman, DS | 1 |
| Campbell, BI | 1 |
| Evans, MJ | 1 |
| Jenkins, MD | 1 |
| Berry, JN | 1 |
| Guillén-Ruiz, G | 1 |
| Cueto-Escobedo, J | 1 |
| Hernández-López, F | 1 |
| Rivera-Aburto, LE | 1 |
| Herrera-Huerta, EV | 1 |
| Rodríguez-Landa, JF | 1 |
| Dickinson, DL | 1 |
| Drummond, SP | 1 |
| McElroy, T | 1 |
| Vieira, JM | 1 |
| Carvalho, FB | 2 |
| Gutierres, JM | 2 |
| Soares, MSP | 1 |
| Oliveira, PS | 1 |
| Rubin, MA | 2 |
| Morsch, VM | 2 |
| Schetinger, MR | 2 |
| Spanevello, RM | 1 |
| Ramlan, NF | 1 |
| Sata, NSAM | 1 |
| Hassan, SN | 1 |
| Bakar, NA | 1 |
| Ahmad, S | 1 |
| Zulkifli, SZ | 1 |
| Abdullah, CAC | 1 |
| Ibrahim, WNW | 1 |
| Lopez-Luna, J | 1 |
| Al-Jubouri, Q | 1 |
| Al-Nuaimy, W | 1 |
| Sneddon, LU | 1 |
| Sallaberry, C | 3 |
| Ardais, AP | 4 |
| Rocha, A | 1 |
| Borges, MF | 3 |
| Fioreze, GT | 2 |
| Mioranzza, S | 2 |
| Pagnussat, N | 2 |
| Botton, PHS | 1 |
| Porciúncula, LO | 3 |
| Giles, GE | 1 |
| Spring, AM | 1 |
| Urry, HL | 1 |
| Moran, JM | 1 |
| Mahoney, CR | 1 |
| Kanarek, RB | 1 |
| Matovu, D | 1 |
| Alele, PE | 1 |
| Takemoto, H | 1 |
| Takahashi, J | 1 |
| Hyuga, S | 1 |
| Odaguchi, H | 1 |
| Uchiyama, N | 1 |
| Maruyama, T | 1 |
| Yamashita, T | 1 |
| Hyuga, M | 1 |
| Oshima, N | 1 |
| Amakura, Y | 1 |
| Hakamatsuka, T | 1 |
| Goda, Y | 1 |
| Hanawa, T | 1 |
| Kobayashi, Y | 1 |
| Hughes, RN | 6 |
| Hamilton, JJ | 1 |
| Schulz, D | 1 |
| Chao, OY | 1 |
| Yunger, R | 1 |
| Yang, YM | 1 |
| Diaz-Manzano, M | 1 |
| Robles-Pérez, JJ | 2 |
| Herrera-Mendoza, K | 1 |
| Herrera-Tapias, B | 1 |
| Fernández-Lucas, J | 1 |
| Aznar-Lain, S | 1 |
| Clemente-Suárez, VJ | 2 |
| Xu, TJ | 1 |
| Reichelt, AC | 1 |
| David, PS | 1 |
| Kling, JM | 1 |
| Vegunta, S | 1 |
| Faubion, SS | 1 |
| Kapoor, E | 1 |
| Mara, KC | 1 |
| Schroeder, DR | 1 |
| Hilsaca, KF | 1 |
| Kuhle, CL | 1 |
| Pedraza, LK | 1 |
| Sierra, RO | 1 |
| Lotz, FN | 1 |
| de Oliveira Alvares, L | 1 |
| van Son, D | 1 |
| Schalbroeck, R | 1 |
| Angelidis, A | 1 |
| van der Wee, NJA | 1 |
| van der Does, W | 1 |
| Putman, P | 1 |
| Lawther, AJ | 1 |
| Flavell, A | 1 |
| Ma, S | 1 |
| Kent, S | 1 |
| Lowry, CA | 1 |
| Gundlach, AL | 1 |
| Hale, MW | 1 |
| Southward, K | 1 |
| Rutherfurd-Markwick, K | 1 |
| Badenhorst, C | 1 |
| Ali, A | 1 |
| Fulton, JL | 1 |
| Dinas, PC | 1 |
| Carrillo, AE | 1 |
| Edsall, JR | 1 |
| Ryan, EJ | 2 |
| da Silva Gonçalves, B | 1 |
| Leal-Rocha, PH | 1 |
| Nelson, ST | 1 |
| Hsiao, L | 1 |
| Hinton, DJ | 1 |
| Andres-Beck, LG | 1 |
| Nett, KE | 1 |
| Oliveros, A | 1 |
| Choi, S | 1 |
| Veldic, M | 1 |
| Choi, DS | 1 |
| Bhatti, SK | 1 |
| O'Keefe, JH | 1 |
| Lavie, CJ | 1 |
| Bhorkar, AA | 1 |
| Dandekar, MP | 1 |
| Nakhate, KT | 1 |
| Subhedar, NK | 1 |
| Kokare, DM | 1 |
| Stefanello, N | 1 |
| Schmatz, R | 1 |
| Pereira, LB | 1 |
| da Rocha, JB | 1 |
| Facco, G | 1 |
| Pereira, ME | 1 |
| Mazzanti, CM | 1 |
| Passamonti, S | 1 |
| Rodrigues, MV | 1 |
| da Rosa, MM | 1 |
| Cardoso, AM | 1 |
| Kromhout, MA | 1 |
| Jongerling, J | 1 |
| Achterberg, WP | 1 |
| Rocha, AS | 2 |
| Cunha, RA | 2 |
| Hancock, NJ | 3 |
| Henwood, GA | 1 |
| Rapley, SA | 1 |
| Maximino, C | 3 |
| da Silva, AW | 2 |
| Araújo, J | 1 |
| Lima, MG | 2 |
| Miranda, V | 1 |
| Puty, B | 1 |
| Benzecry, R | 1 |
| Picanço-Diniz, DL | 2 |
| Oliveira, KR | 1 |
| Yamada, K | 1 |
| Kobayashi, M | 1 |
| Kanda, T | 1 |
| Salinero, JJ | 2 |
| Lara, B | 2 |
| Abian-Vicen, J | 1 |
| Gonzalez-Millán, C | 1 |
| Areces, F | 2 |
| Gallo-Salazar, C | 2 |
| Ruiz-Vicente, D | 2 |
| Del Coso, J | 2 |
| Pané-Farré, CA | 2 |
| Alius, MG | 1 |
| Modeß, C | 2 |
| Methling, K | 1 |
| Blumenthal, T | 1 |
| Hamm, AO | 2 |
| Santos, EC | 1 |
| Bicca, MA | 1 |
| Blum-Silva, CH | 1 |
| Costa, AP | 1 |
| Dos Santos, AA | 1 |
| Schenkel, EP | 1 |
| Farina, M | 1 |
| Reginatto, FH | 1 |
| de Lima, TC | 1 |
| Poole, RL | 1 |
| Braak, D | 1 |
| Gould, TJ | 1 |
| Ladu, F | 1 |
| Mwaffo, V | 1 |
| Li, J | 1 |
| Macrì, S | 1 |
| Benke, C | 1 |
| Blumenthal, TD | 2 |
| Lystrup, RM | 1 |
| Leggit, JC | 1 |
| Richards, G | 1 |
| Smith, A | 1 |
| Turnbull, D | 1 |
| Rodricks, JV | 1 |
| Mariano, GF | 1 |
| Botton, PH | 1 |
| Porciúncula, Lde O | 1 |
| Townsend, SE | 1 |
| Dixon, RS | 1 |
| Hickman, ET | 1 |
| Lee, SM | 1 |
| O'Neill, CE | 1 |
| Newsom, RJ | 1 |
| Stafford, J | 1 |
| Scott, T | 1 |
| Archuleta, S | 1 |
| Levis, SC | 1 |
| Spencer, RL | 1 |
| Campeau, S | 1 |
| Bachtell, RK | 1 |
| Sweeney, P | 1 |
| Levack, R | 1 |
| Watters, J | 1 |
| Xu, Z | 1 |
| Yang, Y | 1 |
| Laureano-Melo, R | 1 |
| da Silveira, AL | 1 |
| de Azevedo Cruz Seara, F | 1 |
| da Conceição, RR | 1 |
| da Silva-Almeida, C | 1 |
| Marinho, BG | 1 |
| da Rocha, FF | 1 |
| Reis, LC | 1 |
| Côrtes, Wda S | 1 |
| Caravan, I | 1 |
| Sevastre Berghian, A | 1 |
| Moldovan, R | 1 |
| Decea, N | 1 |
| Orasan, R | 1 |
| Filip, GA | 1 |
| Puente-Torres, C | 1 |
| Pascual, T | 1 |
| Correa, M | 1 |
| Font, L | 1 |
| Vitale, G | 1 |
| Filaferro, M | 1 |
| Ruggieri, V | 1 |
| Pennella, S | 1 |
| Frigeri, C | 1 |
| Rizzi, A | 2 |
| Guerrini, R | 2 |
| Calò, G | 2 |
| Brooks, KP | 1 |
| Robles, TF | 1 |
| Egan, RJ | 1 |
| Bergner, CL | 1 |
| Hart, PC | 1 |
| Cachat, JM | 1 |
| Canavello, PR | 1 |
| Elegante, MF | 1 |
| Elkhayat, SI | 1 |
| Bartels, BK | 1 |
| Tien, AK | 1 |
| Tien, DH | 1 |
| Mohnot, S | 2 |
| Beeson, E | 2 |
| Glasgow, E | 1 |
| Amri, H | 2 |
| Zukowska, Z | 2 |
| Kalueff, AV | 2 |
| Luebbe, AM | 1 |
| Bell, DJ | 1 |
| Noschang, CG | 1 |
| Pettenuzzo, LF | 1 |
| von Pozzer Toigo, E | 1 |
| Andreazza, AC | 1 |
| Krolow, R | 1 |
| Fachin, A | 1 |
| Avila, MC | 1 |
| Arcego, D | 1 |
| Crema, LM | 1 |
| Diehl, LA | 1 |
| Gonçalvez, CA | 1 |
| Vendite, D | 1 |
| Dalmaz, C | 1 |
| Kumar, A | 1 |
| Garg, R | 1 |
| Gaur, V | 1 |
| Kumar, P | 1 |
| Cachat, J | 1 |
| Canavello, P | 1 |
| Elegante, M | 1 |
| Bartels, B | 1 |
| Hart, P | 1 |
| Bergner, C | 1 |
| Egan, R | 1 |
| Duncan, A | 1 |
| Tien, D | 1 |
| Chung, A | 1 |
| Wong, K | 1 |
| Goodspeed, J | 1 |
| Tan, J | 1 |
| Grimes, C | 1 |
| Elkhayat, S | 1 |
| Suciu, C | 1 |
| Rosenberg, M | 1 |
| Chung, KM | 1 |
| Kadri, F | 1 |
| Roy, S | 1 |
| Gaikwad, S | 1 |
| Stewart, A | 1 |
| Zapolsky, I | 1 |
| Gilder, T | 1 |
| Soignier, RD | 1 |
| Pechlivanova, D | 1 |
| Tchekalarova, J | 1 |
| Nikolov, R | 1 |
| Yakimova, K | 1 |
| Rogers, PJ | 3 |
| Hohoff, C | 1 |
| Heatherley, SV | 2 |
| Mullings, EL | 2 |
| Maxfield, PJ | 1 |
| Evershed, RP | 1 |
| Deckert, J | 4 |
| Nutt, DJ | 1 |
| Park, KS | 1 |
| Oh, JH | 1 |
| Yoo, HS | 1 |
| Lee, YM | 1 |
| Lee, MK | 1 |
| Hong, JT | 1 |
| Oh, KW | 1 |
| Bradley, BF | 1 |
| Bridges, NJ | 1 |
| Starkey, NJ | 1 |
| Brown, SL | 1 |
| Lea, RW | 1 |
| Yang, A | 1 |
| Childs, E | 1 |
| Palmer, AA | 1 |
| de Wit, H | 2 |
| Braun, AA | 1 |
| Skelton, MR | 1 |
| Vorhees, CV | 1 |
| Williams, MT | 1 |
| Olivera, KR | 1 |
| Smith, JE | 2 |
| Lawrence, AD | 1 |
| Diukova, A | 1 |
| Wise, RG | 1 |
| Domschke, K | 2 |
| Gajewska, A | 2 |
| Winter, B | 2 |
| Herrmann, MJ | 2 |
| Warrings, B | 2 |
| Mühlberger, A | 2 |
| Wosnitza, K | 1 |
| Glotzbach, E | 1 |
| Conzelmann, A | 2 |
| Dlugos, A | 1 |
| Fobker, M | 1 |
| Jacob, C | 2 |
| Arolt, V | 2 |
| Reif, A | 2 |
| Pauli, P | 2 |
| Zwanzger, P | 2 |
| Vila-Luna, S | 1 |
| Cabrera-Isidoro, S | 1 |
| Vila-Luna, L | 1 |
| Juárez-Díaz, I | 1 |
| Bata-García, JL | 1 |
| Alvarez-Cervera, FJ | 1 |
| Zapata-Vázquez, RE | 1 |
| Arankowsky-Sandoval, G | 1 |
| Heredia-López, F | 1 |
| Flores, G | 1 |
| Góngora-Alfaro, JL | 1 |
| Richendrfer, H | 1 |
| Pelkowski, SD | 1 |
| Colwill, RM | 1 |
| Creton, R | 1 |
| Juliano, LM | 1 |
| Evatt, DP | 1 |
| Richards, BD | 1 |
| Griffiths, RR | 2 |
| Hermansen, K | 1 |
| Krogholm, KS | 1 |
| Bech, BH | 1 |
| Dragsted, LO | 1 |
| Hyldstrup, L | 1 |
| Jørgensen, K | 1 |
| Larsen, ML | 1 |
| Tjønneland, AM | 1 |
| Khor, YM | 1 |
| Soga, T | 1 |
| Parhar, IS | 1 |
| Ruiz-Medina, J | 1 |
| Pinto-Xavier, A | 1 |
| Rodríguez-Arias, M | 1 |
| Miñarro, J | 1 |
| Valverde, O | 1 |
| Kucher, EO | 1 |
| Egorov, AIu | 1 |
| Filatova, EV | 1 |
| Kulagina, KO | 1 |
| Chernikova, NA | 1 |
| Sudakov, SK | 2 |
| Medvedeva, OF | 2 |
| Rusakova, IV | 2 |
| Figurina, IB | 1 |
| Leutgeb, U | 1 |
| Martus, P | 1 |
| Keogh, E | 1 |
| Chaloner, N | 1 |
| Papazov, IP | 1 |
| Lyupina, YV | 1 |
| Figurina, IV | 1 |
| Singewald, N | 2 |
| Salchner, P | 1 |
| Sharp, T | 2 |
| Botella, P | 1 |
| Parra, A | 1 |
| Alsene, K | 1 |
| Sand, P | 1 |
| DEL TORTO, U | 1 |
| JANNELLI, E | 1 |
| KROKHINA, EM | 1 |
| LUNDERQUIST, B | 1 |
| Carvalho-Netto, EF | 1 |
| Nunes-de-Souza, RL | 1 |
| Motl, RW | 2 |
| Dishman, RK | 3 |
| Prediger, RD | 1 |
| Batista, LC | 1 |
| Takahashi, RN | 1 |
| Linden, K | 1 |
| Jormanainen, V | 1 |
| Swigonski, NL | 1 |
| Pietilä, K | 1 |
| Broderick, P | 1 |
| Benjamin, AB | 1 |
| Jain, NS | 1 |
| Hirani, K | 1 |
| Chopde, CT | 1 |
| Vautrin, S | 1 |
| Pelloux, Y | 1 |
| Costentin, J | 2 |
| Volcy, M | 1 |
| Tepper, SJ | 1 |
| Rapoport, AM | 1 |
| Sheftell, FD | 1 |
| Bigal, ME | 1 |
| Omvik, S | 1 |
| Pallesen, S | 1 |
| Bjorvatn, B | 1 |
| Thayer, J | 1 |
| Nordhus, IH | 1 |
| Ouellet, N | 1 |
| Morris, DL | 1 |
| Pan, HZ | 1 |
| Chen, HH | 1 |
| Sahún, I | 1 |
| Gallego, X | 1 |
| Gratacòs, M | 1 |
| Murtra, P | 1 |
| Trullás, R | 1 |
| Maldonado, R | 1 |
| Estivill, X | 1 |
| Dierssen, M | 1 |
| McCrae, CS | 1 |
| Rowe, MA | 1 |
| Dautovich, ND | 1 |
| Lichstein, KL | 1 |
| Durrence, HH | 1 |
| Riedel, BW | 1 |
| Taylor, DJ | 1 |
| Bush, AJ | 1 |
| Kulkarni, SK | 1 |
| Singh, K | 1 |
| Bishnoi, M | 1 |
| Vergura, R | 1 |
| Marzola, G | 1 |
| Ruzza, C | 1 |
| Salvadori, S | 1 |
| Regoli, D | 1 |
| Gliottoni, RC | 1 |
| Schmidt, A | 1 |
| Karlson-Stiber, C | 1 |
| Cestari, A | 1 |
| Babbini, M | 1 |
| De Marchi, F | 1 |
| Graziani, G | 1 |
| File, SE | 4 |
| Bond, AJ | 1 |
| Lister, RG | 1 |
| Uhde, TW | 3 |
| Boulenger, JP | 3 |
| Jimerson, DC | 2 |
| Post, RM | 2 |
| Rapoport, JL | 1 |
| Berg, CJ | 1 |
| Ismond, DR | 1 |
| Zahn, TP | 1 |
| Neims, A | 1 |
| Siever, LJ | 1 |
| Vittone, BJ | 1 |
| Roy-Byrne, PP | 1 |
| Veleber, DM | 1 |
| Templer, DI | 1 |
| Charney, DS | 1 |
| Galloway, MP | 1 |
| Heninger, GR | 1 |
| Cobbs, LW | 1 |
| Sawyer, DA | 1 |
| Julia, HL | 1 |
| Turin, AC | 1 |
| Gilliland, K | 1 |
| Andress, D | 1 |
| Greden, JF | 2 |
| Victor, BS | 1 |
| Fontaine, P | 2 |
| Lubetsky, M | 2 |
| White, BC | 1 |
| Lincoln, CA | 1 |
| Pearce, NW | 1 |
| Reeb, R | 1 |
| Vaida, C | 1 |
| Miller, LS | 1 |
| Lombardo, TW | 1 |
| Fowler, SC | 1 |
| Imaizumi, M | 1 |
| Miyazaki, S | 1 |
| Onodera, K | 1 |
| Pritchard, WS | 1 |
| Robinson, JH | 1 |
| deBethizy, JD | 1 |
| Davis, RA | 1 |
| Stiles, MF | 1 |
| Salzer, MS | 1 |
| Berenbaum, H | 1 |
| Haleem, DJ | 1 |
| Yasmeen, A | 1 |
| Parveen, T | 1 |
| Zafar, A | 1 |
| Turner, J | 1 |
| Jain, N | 1 |
| Kemp, N | 1 |
| Adeyemo, O | 1 |
| Buchanan, P | 1 |
| Stone, TW | 1 |
| Jenck, F | 1 |
| Martin, JR | 2 |
| Moreau, JL | 1 |
| Hittner, JB | 1 |
| Bhattacharya, SK | 1 |
| Satyan, KS | 1 |
| Chakrabarti, A | 1 |
| Liguori, A | 2 |
| Hughes, JR | 2 |
| Goldberg, K | 1 |
| Callas, P | 1 |
| Stewart, SH | 1 |
| Karp, J | 1 |
| Pihl, RO | 1 |
| Peterson, RA | 1 |
| Youngstedt, SD | 2 |
| O'Connor, PJ | 2 |
| Crabbe, JB | 2 |
| Lapin, IP | 1 |
| Dager, SR | 1 |
| Layton, ME | 1 |
| Strauss, W | 1 |
| Richards, TL | 1 |
| Heide, A | 1 |
| Friedman, SD | 1 |
| Artru, AA | 1 |
| Hayes, CE | 1 |
| Posse, S | 1 |
| Rao, VS | 1 |
| Santos, FA | 1 |
| Paula, WG | 1 |
| Silva, RM | 1 |
| Campos, AR | 1 |
| Lee, TH | 1 |
| Flaten, MA | 1 |
| Elden, A | 1 |
| El Yacoubi, M | 1 |
| Ledent, C | 1 |
| Parmentier, M | 1 |
| Vaugeois, JM | 1 |
| Silva, RH | 1 |
| Frussa-Filho, R | 1 |
| Dominick, A | 1 |
| MacLaughlin, M | 1 |
| Tanskanen, A | 1 |
| Johansson, B | 1 |
| Halldner, L | 1 |
| Dunwiddie, TV | 1 |
| Masino, SA | 1 |
| Poelchen, W | 1 |
| Giménez-Llort, L | 1 |
| Escorihuela, RM | 1 |
| Fernández-Teruel, A | 1 |
| Wiesenfeld-Hallin, Z | 1 |
| Xu, XJ | 1 |
| Hårdemark, A | 1 |
| Betsholtz, C | 1 |
| Herlenius, E | 1 |
| Fredholm, BB | 1 |
| Bernstein, GA | 1 |
| Carroll, ME | 1 |
| Thuras, PD | 1 |
| Cosgrove, KP | 1 |
| Roth, ME | 1 |
| Jones, N | 1 |
| Duxon, MS | 1 |
| King, SM | 1 |
| Scott, WH | 1 |
| Coyne, KM | 1 |
| Johnson, MM | 1 |
| Lausted, CG | 1 |
| Sahota, M | 1 |
| Johnson, AT | 1 |
| Cole, JO | 1 |
| Pope, HG | 1 |
| LaBrie, R | 1 |
| Ionescu-Pioggia, M | 1 |
| Hyde, JR | 1 |
| Middleton, RA | 1 |
| Upton, LG | 1 |
| Chamberlin, K | 1 |
| Hire, JN | 1 |
| Lutz, EG | 1 |
| Oviasu, VO | 1 |
| Molde, DA | 1 |
| Evans, SM | 1 |
| Carey, GJ | 1 |
| Costall, B | 1 |
| Domeney, AM | 1 |
| Jones, DN | 1 |
| Naylor, RJ | 1 |
| Nielsen, BB | 1 |
| Miaskowski, C | 1 |
| Dibble, SL | 1 |
| Beber, B | 1 |
| Altman, N | 1 |
| McCoy, CB | 1 |
| Krahn, DD | 1 |
| Hasse, S | 1 |
| Ray, A | 1 |
| Gosnell, B | 1 |
| Drewnowski, A | 1 |
| Orlikov, A | 1 |
| Ryzov, I | 1 |
| Mino, Y | 1 |
| Yasuda, N | 1 |
| Fujimura, T | 1 |
| Ohara, H | 1 |
| Golda, V | 1 |
| Petr, R | 1 |
| James, JE | 1 |
| Toner, JM | 1 |
| Close, CF | 1 |
| Ramsay, LE | 1 |
| Dudley, JP | 1 |
| Reynolds, R | 1 |
| Dubrow, TJ | 1 |
| Baldwin, HA | 2 |
| Johnston, AL | 1 |
| Gerhardt, S | 1 |
| Liebman, JM | 1 |
| Rainey, JM | 1 |
| Nesse, RM | 1 |
| Smith, GA | 1 |
| Mattila, M | 1 |
| Seppala, T | 1 |
| Mattila, MJ | 1 |
| Clementz, GL | 1 |
| Dailey, JW | 1 |
| Salem, N | 1 |
| Marangos, PJ | 1 |
| Lader, M | 1 |
| Bruce, M | 1 |
| Hwang, DS | 1 |
| Mietlowski, MJ | 1 |
| Friedman, AP | 1 |
| Thompson, JK | 1 |
| Shanahan, MP | 1 |
| Oettinger, R | 1 |
| Rosenberg, E | 1 |
| Bättig, K | 1 |
| Beer, B | 1 |
| Chasin, M | 1 |
| Clody, DE | 1 |
| Vogel, JR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Caffeine in the Second Stage: A Randomized Control Trial in Low-risk Nulliparous Mothers at Term[NCT05906303] | Phase 1 | 80 participants (Anticipated) | Interventional | 2023-12-01 | Not yet recruiting | ||
| Pilot Study on Subjective Efficiency of Caffeine in ADCY5-related Dyskinesia[NCT04351360] | 20 participants (Anticipated) | Observational | 2020-04-10 | Not yet recruiting | |||
| The Effect of Caffeine Supplementation on Blood Lactate Level, Performance and Post-Training Fatigue in Elite Basketball Players[NCT05916352] | 50 participants (Actual) | Interventional | 2022-07-04 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for caffeine and Anxiety
| Article | Year |
|---|---|
Neurochemical and Behavioral Consequences of Ethanol and/or Caffeine Exposure: Effects in Zebrafish and Rodents.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Ethanol; Motor Activity; Rodentia; Zebrafish | 2022 |
International society of sports nutrition position stand: caffeine and exercise performance.
Topics: Anxiety; Athletic Performance; Caffeine; Capsules; Chewing Gum; Cognition; Cytochrome P-450 CYP1A2; | 2021 |
The Role of Genetics in Moderating the Inter-Individual Differences in the Ergogenicity of Caffeine.
Topics: Anxiety; Athletes; Athletic Performance; Caffeine; Central Nervous System Stimulants; Cytochrome P-4 | 2018 |
Impact of Genetic Variability on Physiological Responses to Caffeine in Humans: A Systematic Review.
Topics: Adult; Anxiety; Basic Helix-Loop-Helix Transcription Factors; Caffeine; Cytochrome P-450 CYP1A2; Fem | 2018 |
Coffee and tea: perks for health and longevity?
Topics: Antioxidants; Anxiety; Blood Glucose; Blood Pressure; Caffeine; Calcium; Cardiovascular Diseases; Co | 2013 |
Involvement of adenosine A2A receptors in depression and anxiety.
Topics: Adenosine A2 Receptor Antagonists; Animals; Anxiety; Caffeine; Depression; Humans; Receptor, Adenosi | 2014 |
Neurobehavioral hazard identification and characterization for caffeine.
Topics: Aggression; Animals; Anxiety; Caffeine; Central Nervous System; Central Nervous System Stimulants; D | 2016 |
Caffeine and psychiatric symptoms: a review.
Topics: Anxiety; Caffeine; Central Nervous System Stimulants; Depression; Humans; Mental Disorders; Primary | 2004 |
[Coffee, caffeine and mental health].
Topics: Adolescent; Adult; Aged; Anxiety; Behavior, Addictive; Caffeine; Coffee; Female; Humans; Male; Menta | 1997 |
Psychobiology of anxiety and anxiety disorders.
Topics: Animals; Anxiety; Anxiety Disorders; Blood Platelets; Caffeine; Carbolines; Carbon Dioxide; Cats; Di | 1985 |
Psychotropic effects of caffeine.
Topics: Affect; Anxiety; Behavior; Caffeine; Depression; Dose-Response Relationship, Drug; Female; Food Anal | 1988 |
States of anxiety and their induction by drugs.
Topics: Animals; Anxiety; Caffeine; Carbolines; Epinephrine; Humans; Lactates; Models, Psychological; Risk; | 1986 |
31 trials available for caffeine and Anxiety
| Article | Year |
|---|---|
Caffeine alters emotion and emotional responses in low habitual caffeine consumers.
Topics: Adult; Anxiety; Caffeine; Emotions; Humans; Hydrocortisone; Placebos; Saliva; Surveys and Questionna | 2018 |
Effectiveness of Psycho-Physiological Portable Devices to Analyse Effect of Ergogenic Aids in Military Population.
Topics: Adult; Anxiety; Arousal; Caffeine; Double-Blind Method; Heart Rate; Humans; Lactic Acid; Male; Milit | 2018 |
Acute effects of caffeine on threat-selective attention: moderation by anxiety and EEG theta/beta ratio.
Topics: Adult; Anxiety; Attentional Bias; Beta Rhythm; Caffeine; Central Nervous System Stimulants; Cross-Ov | 2018 |
The use of energy drinks in sport: perceived ergogenicity and side effects in male and female athletes.
Topics: Adult; Anxiety; Athletes; Athletic Performance; Caffeine; Double-Blind Method; Energy Drinks; Exerci | 2014 |
Anxiety sensitivity and expectation of arousal differentially affect the respiratory response to caffeine.
Topics: Adult; Anxiety; Arousal; Autonomic Nervous System; Blood Pressure; Caffeine; Culture; Double-Blind M | 2015 |
CYP1A2 Genotype Variations Do Not Modify the Benefits and Drawbacks of Caffeine during Exercise: A Pilot Study.
Topics: 5' Flanking Region; Adult; Alleles; Anxiety; Attention; Caffeine; Cytochrome P-450 CYP1A2; Dietary S | 2017 |
Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption.
Topics: Adult; Anxiety; Arousal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Dr | 2010 |
Storm in a coffee cup: caffeine modifies brain activation to social signals of threat.
Topics: Adult; Aged; Anxiety; Arterial Pressure; Brain; Brain Mapping; Caffeine; Double-Blind Method; Expres | 2012 |
Faster but not smarter: effects of caffeine and caffeine withdrawal on alertness and performance.
Topics: Adolescent; Adult; Anxiety; Caffeine; Central Nervous System Stimulants; Cognition; Computers; Dose- | 2013 |
The moderating effect of anxiety sensitivity on caffeine-induced hypoalgesia in healthy women.
Topics: Adolescent; Adult; Affect; Anxiety; Arousal; Blood Pressure; Caffeine; Fear; Female; Humans; Middle | 2002 |
Association between A2a receptor gene polymorphisms and caffeine-induced anxiety.
Topics: Adult; Animals; Anxiety; Caffeine; Central Nervous System Stimulants; Cysteine; Double-Blind Method; | 2003 |
Effects of acute exercise on the soleus H-reflex and self-reported anxiety after caffeine ingestion.
Topics: Adult; Anxiety; Caffeine; Central Nervous System Stimulants; Exercise; Exercise Test; Exercise Thera | 2004 |
Effect of caffeine on leg-muscle pain during intense cycling exercise: possible role of anxiety sensitivity.
Topics: Adult; Analgesics; Anxiety; Bicycling; Caffeine; Central Nervous System Stimulants; Cross-Over Studi | 2008 |
Interaction between effects of caffeine and lorazepam in performance tests and self-ratings.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Caffeine; Drug Interactions; Emotions; Female; Flicker Fusion; | 1982 |
Caffeine: relationship to human anxiety, plasma MHPG and cortisol.
Topics: Anxiety; Caffeine; Glycols; Humans; Hydrocortisone; Methoxyhydroxyphenylglycol | 1984 |
Behavioral effects of caffeine in children. Relationship between dietary choice and effects of caffeine challenge.
Topics: Adolescent; Anxiety; Arousal; Attention; Caffeine; Child; Child Behavior; Choice Behavior; Diet; Dou | 1984 |
Anxiety and muscle tension as consequences of caffeine withdrawal.
Topics: Adult; Anxiety; Caffeine; Humans; Muscle Contraction; Substance Withdrawal Syndrome | 1980 |
Caffeine and time of day effects on a force discrimination task in humans.
Topics: Adult; Affect; Anxiety; Body Temperature; Caffeine; Circadian Rhythm; Discrimination, Psychological; | 1995 |
Caffeine and smoking: subjective, performance, and psychophysiological effects.
Topics: Adult; Anxiety; Arousal; Attention; Brain Mapping; Caffeine; Cerebral Cortex; Double-Blind Method; D | 1995 |
Subjective effects of oral caffeine in formerly cocaine-dependent humans.
Topics: Administration, Oral; Adult; Anxiety; Caffeine; Cocaine-Related Disorders; Cross-Over Studies; Dose- | 1997 |
Caffeine and prepulse inhibition of the acoustic startle reflex.
Topics: Acoustic Stimulation; Adult; Anxiety; Arousal; Attention; Blinking; Blood Pressure; Caffeine; Centra | 1999 |
The influence of acute exercise on sleep following high caffeine intake.
Topics: Adult; Anxiety; Arousal; Body Temperature; Caffeine; Central Nervous System Stimulants; Electroencep | 2000 |
Effect of smoking abstinence on the subjective effects of caffeine.
Topics: Adolescent; Adult; Anxiety; Caffeine; Double-Blind Method; Drug Interactions; Female; Humans; Male; | 1999 |
Effects of caffeine on performance of low intensity tasks.
Topics: Adult; Anxiety; Arousal; Attention; Caffeine; Female; Humans; Logic; Male; Neuropsychological Tests; | 2002 |
Assessing the subjective effects of stimulants in casual users. A methodology and preliminary results.
Topics: Adult; Anxiety; Caffeine; Central Nervous System Stimulants; Depression; Dextroamphetamine; Emotions | 1978 |
Postoperative evaluation of combined analgesic/sedative.
Topics: Anxiety; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Humans; Pain, Post | 1978 |
Evaluation of sedative/analgesic combination for postoperative pain.
Topics: Anxiety; Aspirin; Caffeine; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug E | 1979 |
The influence of user status and anxious disposition on the hypertensive effects of caffeine.
Topics: Adult; Anxiety; Blood Pressure; Caffeine; Double-Blind Method; Electromyography; Female; Hand; Heart | 1990 |
Anxiogenic effect of yohimbine in healthy subjects: comparison with caffeine and antagonism by clonidine and diazepam.
Topics: Adult; Anxiety; Arousal; Caffeine; Clonidine; Diazepam; Dose-Response Relationship, Drug; Double-Bli | 1988 |
Plasma adenosine levels: measurement in humans and relationship to the anxiogenic effects of caffeine.
Topics: Adenosine; Adult; Anxiety; Caffeine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dou | 1987 |
Fiorinal with Codeine in the management of tension headache: impact of placebo response.
Topics: Adult; Anxiety; Aspirin; Barbiturates; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Met | 1987 |
161 other studies available for caffeine and Anxiety
| Article | Year |
|---|---|
Caffeine-related genes influence anxiety disorders in children and adults with ADHD.
Topics: Adult; Anxiety; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Caffeine; Central | 2022 |
Caffeine Intake and Its Sex-Specific Association with General Anxiety: A Cross-Sectional Analysis among General Population Adults.
Topics: Adult; Aged; Anxiety; Anxiety Disorders; Caffeine; Cross-Sectional Studies; Female; Humans; Logistic | 2022 |
Effect Of Caffeine and Adrenaline on Memory and Anxiety in Male Wistar Rats.
Topics: Animals; Anxiety; Caffeine; Epinephrine; Male; Maze Learning; Rats; Rats, Wistar; Saline Solution | 2022 |
The larval diving response (LDR): Validation of an automated, high-throughput, ecologically relevant measure of anxiety-related behavior in larval zebrafish (Danio rerio).
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Diazepam; Disease Models, Animal; | 2022 |
Incorporating ventilatory activity into a novel tank test for evaluating drug effects on zebrafish.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Ethanol; Zebrafish | 2022 |
Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice.
Topics: Animals; Anxiety; Caffeine; Cholinergic Agents; Hypnotics and Sedatives; Lavandula; Mice; Oils, Vola | 2023 |
Adenosine receptors participate in anabolic-androgenic steroid-induced changes on risk assessment/anxiety-like behaviors in male and female rats.
Topics: Anabolic Agents; Anabolic Androgenic Steroids; Animals; Anxiety; Caffeine; Female; Male; Nandrolone | 2023 |
Caffeine Motives and Expectancies for Individuals with High Anxiety Sensitivity.
Topics: Adaptation, Psychological; Alcohol Drinking; Anxiety; Anxiety Disorders; Caffeine; Fear; Humans; Mot | 2023 |
Lifetime caffeine and adolescent nicotine exposure in mice: effects on anxiety-like behavior and reward.
Topics: Adolescent; Animals; Anxiety; Behavior, Animal; Caffeine; Dopamine; Humans; Mice; Nicotine; Reward | 2023 |
Environmental stressors differentially modulate anxiety-like behaviour in male and female zebrafish.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Female; Male; Zebrafish | 2023 |
Acute caffeine differently affects risk-taking and the expression of BDNF and of adenosine and opioid receptors in rats with high or low anxiety-like behavior.
Topics: Adenosine; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Caffeine; Rats; Receptors, Opioid; R | 2023 |
Inversely Regulated Inflammation-Related Processes Mediate Anxiety-Obesity Links in Zebrafish Larvae and Adults.
Topics: Animals; Anxiety; Caffeine; Inflammation; Larva; Obesity; Zebrafish | 2023 |
Caffeine alleviates anxiety-like behavior and brainstem lesions in a rotenone-induced rat model of Parkinson's disease.
Topics: Animals; Anxiety; Caffeine; Disease Models, Animal; Dopamine; Male; Mesencephalon; Neuroprotective A | 2023 |
LSGP-USFNet: Automated Attention Deficit Hyperactivity Disorder Detection Using Locations of Sophie Germain's Primes on Ulam's Spiral-Based Features with Electroencephalogram Signals.
Topics: Algorithms; Anxiety; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Caffeine; Chi | 2023 |
Acute low dose caffeine affects behavior profile and activity, an examination of male rats with high or low anxiety-like behavior.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Exploratory Behavior; Humans; Mal | 2023 |
Relationship between Baseline Physical Activity and Generalized Anxiety Disorder and Major Depressive Disorder Treatment Outcomes.
Topics: Adult; Anxiety; Anxiety Disorders; Caffeine; Depression; Depressive Disorder, Major; Humans; Retrosp | 2023 |
Data-driven modeling of zebrafish behavioral response to acute caffeine administration.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Data Analysis; Locomotion; Zebrafish | 2020 |
Lacidipine attenuates caffeine-induced anxiety-like symptoms in mice: Role of calcium-induced oxido-nitrosative stress.
Topics: Animals; Anxiety; Behavior, Animal; Biomarkers; Brain; Caffeine; Calcium; Depression; Dihydropyridin | 2019 |
Oxidative Stress Mediates Anxiety-Like Behavior Induced by High Caffeine Intake in Zebrafish: Protective Effect of Alpha-Tocopherol.
Topics: alpha-Tocopherol; Animals; Antioxidants; Anxiety; Caffeine; Disease Models, Animal; Female; Oxidativ | 2019 |
Three- and bi-dimensional analyses of the shoaling behavior in zebrafish: Influence of modulators of anxiety-like responses.
Topics: Algorithms; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Diazepam; Exploratory | 2020 |
Trait specific modulatory effects of caffeine exposure on compulsive-like behaviors in a spontaneous mouse model of obsessive-compulsive disorder.
Topics: Animals; Animals, Outbred Strains; Anxiety; Caffeine; Central Nervous System Stimulants; Disease Mod | 2020 |
Pharmacological depletion of serotonin and norepinephrine with para-chlorophenylalanine and alpha-methyl-p-tyrosine reverses the antidepressant-like effects of adolescent caffeine exposure in the male rat.
Topics: Age Factors; alpha-Methyltyrosine; Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Behav | 2020 |
Low but not moderate amounts of caffeine increase co-consumption of ethanol in C57BL/6J mice.
Topics: Alcohol Drinking; Animals; Anxiety; Behavior, Animal; Binge Drinking; Caffeine; Disease Models, Anim | 2021 |
Estrous cycle modulates the anxiogenic effects of caffeine in the elevated plus maze and light/dark box in female rats.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Elevated Plus Maze | 2021 |
The viability of an ecologically valid chronic sleep restriction and circadian timing protocol: An examination of sample attrition, compliance, and effectiveness at impacting sleepiness and mood.
Topics: Actigraphy; Adolescent; Adult; Affect; Anxiety; Behavior; Caffeine; Circadian Rhythm; Depression; Fe | 2017 |
Caffeine prevents high-intensity exercise-induced increase in enzymatic antioxidant and Na
Topics: Animals; Anti-Anxiety Agents; Antioxidants; Anxiety; Caffeine; Catalase; Glutathione; Glutathione Pe | 2017 |
Time dependent effect of chronic embryonic exposure to ethanol on zebrafish: Morphology, biochemical and anxiety alterations.
Topics: Animals; Anxiety; Apoptosis; Avoidance Learning; Caffeine; Central Nervous System Depressants; Dose- | 2017 |
Impact of stress, fear and anxiety on the nociceptive responses of larval zebrafish.
Topics: Acetic Acid; Analgesics; Animals; Anxiety; Behavior, Animal; Caffeine; Diazepam; Etomidate; Fear; La | 2017 |
Sex differences in the effects of pre- and postnatal caffeine exposure on behavior and synaptic proteins in pubescent rats.
Topics: Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Caffeine; Central Nervous System Stimula | 2018 |
Seizure vulnerability and anxiety responses following chronic co-administration and acute withdrawal of caffeine and ethanol in a rat model.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Ethanol; Male; Pentylenetetrazole; Rats; Rats, Sprague | 2018 |
Different effects of caffeine on behavioral neurophenotypes of two zebrafish populations.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Exploratory Behavio | 2018 |
Ephedrine Alkaloids-Free Ephedra Herb Extract, EFE, Has No Adverse Effects Such as Excitation, Insomnia, and Arrhythmias.
Topics: Alkaloids; Analgesics, Non-Narcotic; Animals; Animals, Outbred Strains; Anxiety; Arrhythmias, Cardia | 2018 |
Sex-dependent modification by chronic caffeine of acute methamphetamine effects on anxiety-related behavior in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Drug Administration Schedule; Drug Therapy, Combina | 2018 |
Acute food deprivation separates motor-activating from anxiolytic effects of caffeine in a rat open field test model.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Disease Models, Animal; Exploratory Behavior; Femal | 2018 |
Behavioral assessments of BTBR T+Itpr3tf/J mice by tests of object attention and elevated open platform: Implications for an animal model of psychiatric comorbidity in autism.
Topics: Animals; Anxiety; Attention; Autistic Disorder; Caffeine; Comorbidity; Disease Models, Animal; Explo | 2018 |
Sucrose or sucrose and caffeine differentially impact memory and anxiety-like behaviours, and alter hippocampal parvalbumin and doublecortin.
Topics: Animals; Anxiety; Basolateral Nuclear Complex; Caffeine; Dietary Sucrose; Doublecortin Domain Protei | 2018 |
Vasomotor symptoms in women over 60: results from the Data Registry on Experiences of Aging, Menopause, and Sexuality (DREAMS).
Topics: Aged; Anxiety; Caffeine; Cohort Studies; Cross-Sectional Studies; Drug-Related Side Effects and Adve | 2018 |
Periodical reactivation under the effect of caffeine attenuates fear memory expression in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Conditioning, Classical; Conditioning, Psychologica | 2018 |
Involvement of Serotonergic and Relaxin-3 Neuropeptide Systems in the Expression of Anxiety-like Behavior.
Topics: Animals; Anxiety; Caffeine; Male; Nerve Tissue Proteins; Prosencephalon; Raphe Nuclei; Rats, Wistar; | 2018 |
Lifelong exposure to caffeine increases anxiety-like behavior in adult mice exposed to tobacco smoke during adolescence.
Topics: Aging; Animals; Anxiety; Behavior, Animal; Caffeine; Cotinine; Exploratory Behavior; Female; Male; M | 2019 |
Sex and housing conditions modify the effects of adolescent caffeine exposure on anxiety-like and depressive-like behavior in the rat.
Topics: Age Factors; Animals; Anxiety; Anxiety Disorders; Behavior, Animal; Caffeine; Depression; Depressive | 2019 |
Chronic caffeine exposure in adolescence promotes diurnal, biphasic mood-cycling and enhanced motivation for reward in adult mice.
Topics: Affect; Age Factors; Animals; Anxiety; Behavior, Animal; Caffeine; Depression; Locomotion; Male; Mic | 2019 |
Involvement of the central melanocortin system in the effects of caffeine on anxiety-like behavior in mice.
Topics: alpha-MSH; Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Drug Tol | 2014 |
Effects of chlorogenic acid, caffeine, and coffee on behavioral and biochemical parameters of diabetic rats.
Topics: Acetylcholinesterase; Animals; Anxiety; Behavior, Animal; Body Weight; Caffeine; Cerebral Cortex; Ch | 2014 |
Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study.
Topics: Aged, 80 and over; Anxiety; Apathy; Behavioral Symptoms; Caffeine; Dementia; Female; Humans; Male; M | 2014 |
Caffeine triggers behavioral and neurochemical alterations in adolescent rats.
Topics: Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Caffeine; Central Nervous System Stimula | 2014 |
Evidence for anxiolytic effects of acute caffeine on anxiety-related behavior in male and female rats tested with and without bright light.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Female; Grooming; Locomotion; Mal | 2014 |
Fingerprinting of psychoactive drugs in zebrafish anxiety-like behaviors.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Caffeine; Diazepam; Drug Evaluation, Preclinical; | 2014 |
Anxiolytic-like, stimulant and neuroprotective effects of Ilex paraguariensis extracts in mice.
Topics: Acetylcholinesterase; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Brain; Caffeine; Ce | 2015 |
Concentration- and age-dependent effects of chronic caffeine on contextual fear conditioning in C57BL/6J mice.
Topics: Aging; Animals; Anxiety; Caffeine; Central Nervous System Stimulants; Conditioning, Psychological; D | 2016 |
Acute effects of caffeine supplementation on cortical arousal, anxiety, physiological response and marksmanship in close quarter combat.
Topics: Adult; Anxiety; Arousal; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Firearms; | 2015 |
Acute caffeine administration affects zebrafish response to a robotic stimulus.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Information Theory; Robotics; Social Behavior; Zebrafi | 2015 |
Effects of anxiety sensitivity and expectations on the modulation of the startle eyeblink response during a caffeine challenge.
Topics: Adult; Anticipation, Psychological; Anxiety; Anxiety Disorders; Arousal; Attention; Autonomic Nervou | 2015 |
Caffeine Toxicity Due to Supplement Use in Caffeine--Naïve Individual: A Cautionary Tale.
Topics: Adult; Anxiety; Caffeine; Central Nervous System Stimulants; Dietary Supplements; Follow-Up Studies; | 2015 |
Caffeine consumption and self-assessed stress, anxiety, and depression in secondary school children.
Topics: Adolescent; Anxiety; Anxiety Disorders; Caffeine; Carbonated Beverages; Child; Coffee; Cross-Section | 2015 |
Strain-dependent effects of acute caffeine on anxiety-related behavior in PVG/c, Long-Evans and Wistar rats.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Defecation; Explora | 2016 |
Caffeine exposure during rat brain development causes memory impairment in a sex selective manner that is offset by caffeine consumption throughout life.
Topics: Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Caffeine; Central Nervous System Stimula | 2016 |
Chronic caffeine produces sexually dimorphic effects on amphetamine-induced behavior, anxiety and depressive-like behavior in adolescent rats.
Topics: Amphetamines; Animals; Anxiety; Behavior, Animal; Caffeine; Depression; Female; Male; Rats; Rats, Sp | 2016 |
Adolescent caffeine consumption increases adulthood anxiety-related behavior and modifies neuroendocrine signaling.
Topics: Adrenocorticotropic Hormone; Aging; Amygdala; Animals; Anxiety; Behavior, Animal; Caffeine; Corticos | 2016 |
Caffeine increases food intake while reducing anxiety-related behaviors.
Topics: Animals; Anxiety; Appetite; Behavior, Animal; Body Weight; Caffeine; Dose-Response Relationship, Dru | 2016 |
Behavioral profile assessment in offspring of Swiss mice treated during pregnancy and lactation with caffeine.
Topics: Animals; Anxiety; Caffeine; Central Nervous System Stimulants; Female; Hyperalgesia; Lactation; Male | 2016 |
Modulatory effects of caffeine on oxidative stress and anxiety-like behavior in ovariectomized rats.
Topics: Animals; Antioxidants; Anxiety; Brain; Caffeine; Catalase; Female; Glutathione; Glutathione Peroxida | 2016 |
Effects of acute caffeine on anxiety-related behavior in rats chronically exposed to the drug, with some evidence of possible withdrawal-reversal.
Topics: Animals; Anxiety; Caffeine; Central Nervous System Stimulants; Exploratory Behavior; Female; Male; M | 2017 |
Is there a major role for adenosine A2A receptors in anxiety?
Topics: Adenosine A2 Receptor Antagonists; Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Anxiet | 2008 |
Anxiolytic-like effect of neuropeptide S in the rat defensive burying.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Diazepam; Humans; Male; Neuropept | 2008 |
Recent depressive and anxious symptoms predict cortisol responses to stress in men.
Topics: Alcohol Drinking; Anxiety; Caffeine; Depression; Female; Health Behavior; Humans; Hydrocortisone; Ma | 2009 |
Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Caffeine; Central Nerv | 2009 |
Mountain Dew or mountain don't?: a pilot investigation of caffeine use parameters and relations to depression and anxiety symptoms in 5th- and 10th-grade students.
Topics: Adolescent; Anxiety; Caffeine; Child; Cross-Sectional Studies; Depression; Female; Humans; Male; Pil | 2009 |
Sex-specific differences on caffeine consumption and chronic stress-induced anxiety-like behavior and DNA breaks in the hippocampus.
Topics: Adrenal Glands; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous | 2009 |
Venlafaxine involves nitric oxide modulatory mechanism in experimental model of chronic behavior despair in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Arginine; Caffeine; Central Nervous Syst | 2010 |
Modeling withdrawal syndrome in zebrafish.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Diazepam; Disease Models, Animal; Ethanol; Exploratory | 2010 |
Dose-dependent effects of caffeine on behavior and thermoregulation in a chronic unpredictable stress model of depression in rats.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Body Temperature Regulation; Caffeine; Cen | 2010 |
(-)-Epigallocatechin-3-O-gallate (EGCG) reverses caffeine-induced anxiogenic-like effects.
Topics: Animals; Anxiety; Caffeine; Catechin; Central Nervous System Stimulants; Disease Models, Animal; Dos | 2010 |
Anxiolytic and anxiogenic drug effects on male and female gerbils in the black-white box.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Caffeine; Carbolines; Central Ne | 2011 |
More on ADORA.
Topics: Anxiety; Caffeine; Central Nervous System Stimulants; Coffee; Drinking Behavior; Feeding Behavior; G | 2010 |
Comparison of the elevated plus and elevated zero mazes in treated and untreated male Sprague-Dawley rats: effects of anxiolytic and anxiogenic agents.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Diazepam; Female; Male; Maze Lear | 2011 |
Adult anxiety-related behavior of rats following consumption during late adolescence of alcohol alone and in combination with caffeine.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Caffeine; Drug Combinations; Drug Synergism; Ethanol; Fem | 2011 |
Pharmacological analysis of zebrafish (Danio rerio) scototaxis.
Topics: Adaptation, Ocular; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; | 2011 |
Adenosine A1, but not A2, receptor blockade increases anxiety and arousal in Zebrafish.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Anxiety; Arousal; Beh | 2011 |
ADORA2A Gene variation, caffeine, and emotional processing: a multi-level interaction on startle reflex.
Topics: Adult; Anxiety; Caffeine; Double-Blind Method; Emotions; Female; Genetic Predisposition to Disease; | 2012 |
Chronic caffeine consumption prevents cognitive decline from young to middle age in rats, and is associated with increased length, branching, and spine density of basal dendrites in CA1 hippocampal neurons.
Topics: Aging; Animals; Anxiety; CA1 Region, Hippocampal; Caffeine; Central Nervous System Stimulants; Cogni | 2012 |
On the edge: pharmacological evidence for anxiety-related behavior in zebrafish larvae.
Topics: Animals; Anxiety; Caffeine; Cues; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug | 2012 |
Characterization of individuals seeking treatment for caffeine dependence.
Topics: Adult; Anxiety; Caffeine; Coffee; Female; Humans; Male; Middle Aged; Sleep Wake Disorders; Substance | 2012 |
Effects of ADORA2A gene variation and caffeine on prepulse inhibition: a multi-level risk model of anxiety.
Topics: Adult; Anxiety; Caffeine; Female; Genetic Variation; Genotype; Humans; Male; Receptor, Adenosine A2A | 2013 |
[Coffee can protect against disease].
Topics: Alzheimer Disease; Anxiety; Caffeine; Cardiovascular Diseases; Coffee; Cognition; Diabetes Mellitus, | 2012 |
Caffeine neuroprotects against dexamethasone-induced anxiety-like behaviour in the Zebrafish (Danio rerio).
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Dexamethasone; Hydrocortisone; Hypothalamus; Male; Rec | 2013 |
Influence of chronic caffeine on MDMA-induced behavioral and neuroinflammatory response in mice.
Topics: Animals; Anxiety; Astrocytes; Behavior, Animal; Body Temperature; Caffeine; Central Nervous System S | 2013 |
[Gender influence on the formation of alcohol preference and combination of alcohol with caffein in the condition of the long-term experiment].
Topics: Alcohol Drinking; Animals; Anxiety; Caffeine; Drug-Seeking Behavior; Ethanol; Female; Male; Rats; Ra | 2012 |
Effect of short-term and chronic caffeine intake on rats with various anxiety level.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Environment; Light; | 2001 |
Regular intake of non-opioid analgesics is associated with an increased risk of restless legs syndrome in patients maintained on antidepressants.
Topics: Adrenergic beta-Antagonists; Adult; Analgesics, Non-Narcotic; Antidepressive Agents, Tricyclic; Anti | 2002 |
Effects of acute and chronic caffeine intake on intravenous self-administration of morphine in two rat strains.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Dose-Response Relationship, Drug; Feeding Behavior; Ma | 2002 |
Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs.
Topics: Adrenergic alpha-Antagonists; Amygdala; Animals; Anxiety; Caffeine; Carbolines; Central Nervous Syst | 2003 |
Coffee increases state anxiety in males but not in females.
Topics: Adolescent; Adult; Anxiety; Blood Pressure; Caffeine; Central Nervous System Stimulants; Chromatogra | 2003 |
[Therapeutic possibility of impletol in motor changes of nervous origin].
Topics: Anxiety; Caffeine; Drug Combinations; Humans; Paralysis; Procaine | 1954 |
[Histopathology of the nervous elements of the heart and aorta in dogs following administration of adrenalin and caffeine].
Topics: Animals; Anxiety; Aorta; Caffeine; Dogs; Epinephrine; Heart; Musculoskeletal Physiological Phenomena | 1961 |
[TRIAL OF SINEDYL WITH NEUROTIC PATIENTS IN GENERAL PRACTICE].
Topics: Anxiety; Anxiety Disorders; Atropa belladonna; Biomedical Research; Caffeine; General Practice; Huma | 1964 |
Use of the elevated T-maze to study anxiety in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; | 2004 |
Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor | 2004 |
Self-medication among Finnish young men in the beginning of common military service.
Topics: Adult; Anxiety; Caffeine; Central Nervous System Stimulants; Common Cold; Cross-Sectional Studies; E | 2005 |
Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats.
Topics: Adrenalectomy; Analysis of Variance; Anesthetics; Animals; Anxiety; Bicuculline; Caffeine; Central N | 2005 |
Preference for caffeine appears earlier in non-anxious than in anxious mice.
Topics: Administration, Oral; Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System Stimulant | 2005 |
Botulinum toxin A for the treatment of greater occipital neuralgia and trigeminal neuralgia: a case report with pathophysiological considerations.
Topics: Acetaminophen; Adult; Analgesics; Anxiety; Aspirin; Botulinum Toxins, Type A; Caffeine; Colitis, Ulc | 2006 |
Night-time thoughts in high and low worriers: reaction to caffeine-induced sleeplessness.
Topics: Adolescent; Adult; Anxiety; Caffeine; Female; Humans; Psychometrics; Sleep Initiation and Maintenanc | 2007 |
Sleep satisfaction of older adults living in the community: identifying associated behavioral and health factors.
Topics: Aged; Anxiety; Attitude to Health; Caffeine; Cross-Sectional Studies; Depression; Drug-Related Side | 2006 |
Hyperalgesia, low-anxiety, and impairment of avoidance learning in neonatal caffeine-treated rats.
Topics: Adenosine; Animals; Animals, Newborn; Anxiety; Avoidance Learning; Behavior, Animal; Body Temperatur | 2007 |
Differential responses to anxiogenic drugs in a mouse model of panic disorder as revealed by Fos immunocytochemistry in specific areas of the fear circuitry.
Topics: Animals; Anxiety; Brain; Caffeine; Disease Models, Animal; Fear; Male; Mice; Mice, Transgenic; Oncog | 2007 |
Sleep hygiene practices in two community dwelling samples of older adults.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Anxiety; Caffeine; Central Nervous System Stimulants; Dem | 2006 |
Involvement of adenosinergic receptors in anxiety related behaviours.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Dose-Response Relation | 2007 |
Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Body Temperature Regulation; Caffeine; Cent | 2008 |
Caffeine poisoning and lactate rise: an overlooked toxic effect?
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidotes; Anxiety; Caffeine; Central | 2008 |
Central nervous system activity of 1-(3-methoxypropylamino)-2-hydroxy-2-(1,4-benzodioxan-2-yl)-ethane hydrochloride.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System; Chlorpromazine; Desipramine; D | 1967 |
Fear and anxiety: relationship to noradrenergic function.
Topics: Animals; Anxiety; Caffeine; Clonidine; Dose-Response Relationship, Drug; Fear; Humans; Locus Coerule | 1984 |
Effects of caffeine on anxiety and depression.
Topics: Adult; Anxiety; Caffeine; Depression; Double-Blind Method; Female; Hostility; Humans; Male | 1984 |
The effects of caffeine on plasma MHPG, subjective anxiety, autonomic symptoms and blood pressure in healthy humans.
Topics: Adult; Anxiety; Autonomic Nervous System; Behavior; Blood Pressure; Caffeine; Female; Glycols; Heart | 1984 |
Lethargy, anxiety, and impotence in a diabetic.
Topics: Adult; Anxiety; Caffeine; Diabetes Complications; Diabetes Mellitus; Erectile Dysfunction; Humans; H | 1982 |
Caffeine and human behavior: arousal, anxiety, and performance effects.
Topics: Achievement; Anxiety; Arousal; Caffeine; Cerebral Cortex; Humans; Substance Withdrawal Syndrome | 1982 |
Ad lib caffeine consumption, symptoms of caffeinism, and academic performance.
Topics: Age Factors; Anxiety; Caffeine; Depression; Female; Humans; Male; Psychophysiologic Disorders; Sex F | 1981 |
Caffeine-withdrawal headache: a clinical profile.
Topics: Adult; Anxiety; Caffeine; Depression; Female; Headache; Humans; Substance Withdrawal Syndrome | 1980 |
Effects of xanthine derivatives in a light/dark test in mice and the contribution of adenosine receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Int | 1994 |
Somatic sensations, anxiety, and control in panic disorder.
Topics: Adult; Agoraphobia; Anxiety; Arousal; Behavior Therapy; Caffeine; Combined Modality Therapy; Feeding | 1994 |
Enhancement of hepatic tryptophan pyrrolase activity and decreases of open field locomotion following single and repeated administration of high doses of caffeine in rats.
Topics: Animals; Anxiety; Caffeine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Kynurenin | 1994 |
Incidental information processing: effects of mood, sex and caffeine.
Topics: Adult; Affect; Anxiety; Caffeine; Depression; Dominance, Cerebral; Female; Humans; Male; Memory; Men | 1993 |
Anxiolytic activity of adenosine receptor activation in mice.
Topics: Adenosine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Male; Maze Learnin | 1995 |
Behavioral effects of CCKB receptor ligands in a validated simulation of panic anxiety in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Caffeine; Clonazepam; Dose-Response Relati | 1996 |
A preliminary analysis of the perceived risks of misusing multiple substances, trait anxiety, and approval motivation.
Topics: Adolescent; Adult; Alcohol Drinking; Anxiety; Attitude to Health; Caffeine; Cocaine; Female; Health | 1997 |
Anxiogenic action of caffeine: an experimental study in rats.
Topics: Animals; Anxiety; Caffeine; Central Nervous System Stimulants; Drug Tolerance; Exploratory Behavior; | 1997 |
Anxiety sensitivity and self-reported reasons for drug use.
Topics: Adaptation, Psychological; Adolescent; Adult; Alcohol Drinking; Anxiety; Caffeine; Disease Susceptib | 1997 |
Acute exercise reduces caffeine-induced anxiogenesis.
Topics: Adult; Anxiety; Bicycling; Blood Pressure; Caffeine; Central Nervous System Stimulants; Exercise; Ex | 1998 |
Antagonism of kynurenic acid to anxiogens in mice.
Topics: Animals; Anxiety; Brain; Caffeine; Diazepam; Excitatory Amino Acid Antagonists; Injections, Intraper | 1998 |
Human brain metabolic response to caffeine and the effects of tolerance.
Topics: Adult; Anxiety; Arousal; Aspartic Acid; Brain; Caffeine; Citrates; Coffee; Drug Combinations; Echo-P | 1999 |
Effects of acute and repeated dose administration of caffeine and pentoxifylline on diazepam-induced mouse behavior in the hole-board test.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Caffeine; Diazepam; Disease Models, Animal | 1999 |
Puzzling through a case. The sleepless professor.
Topics: Age Factors; Aged; Anxiety; Caffeine; Central Nervous System Stimulants; Exercise; Humans; Male; Sle | 1999 |
The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists.
Topics: Adenosine; Administration, Oral; Animals; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Admini | 2000 |
Neuroanatomical targets of anxiogenic drugs in the hindbrain as revealed by Fos immunocytochemistry.
Topics: Adrenergic alpha-Antagonists; Animals; Anxiety; Caffeine; Carbolines; Central Nervous System Stimula | 2000 |
The plus-maze discriminative avoidance task: a new model to study memory-anxiety interactions. Effects of chlordiazepoxide and caffeine.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Caffeine; Central Nervous System Stimulan | 2000 |
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor.
Topics: Adenosine; Animals; Anxiety; Autoradiography; Behavior, Animal; Caffeine; Hippocampus; Hyperalgesia; | 2001 |
Caffeine dependence in teenagers.
Topics: Adolescent; Alcohol Drinking; Analysis of Variance; Anxiety; Caffeine; Central Nervous System Stimul | 2002 |
Ethopharmacological analysis of the unstable elevated exposed plus maze, a novel model of extreme anxiety: predictive validity and sensitivity to anxiogenic agents.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Caffeine; Ca | 2002 |
A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Central Nervous System Stimulants; Flu | 1979 |
Anxiety and depression associated with caffeinism among psychiatric inpatients.
Topics: Anxiety; Caffeine; Depression; Hospitalization; Humans; Mental Disorders; Psychological Tests | 1978 |
Anxiety and caffeine.
Topics: Achievement; Adult; Alcohol Drinking; Anxiety; Caffeine; Coffee; Female; Humans; Male | 1978 |
Restless legs, anxiety and caffeinism.
Topics: Adolescent; Adult; Anxiety; Arousal; Caffeine; Coffee; Depression; Female; Humans; Male; Muscle Cont | 1978 |
Abuse of stimulant drugs in Nigeria.
Topics: Adolescent; Adult; Anxiety; Caffeine; Dextroamphetamine; Drug Synergism; Female; Humans; Male; Niger | 1976 |
Letter: Diagnosing caffeinism.
Topics: Affective Symptoms; Anxiety; Caffeine; Coffee; Drinking; Humans; Male | 1975 |
Caffeine tolerance and choice in humans.
Topics: Adult; Affect; Anxiety; Caffeine; Diet; Drug Tolerance; Female; Humans; Male; Psychiatric Status Rat | 1992 |
Behavioural effects of anxiogenic agents in the common marmoset.
Topics: Amphetamine; Animals; Anxiety; Behavior, Animal; Caffeine; Callithrix; Carbolines; Diazepam; Motor A | 1992 |
Pain and discomfort associated with film-screen mammography.
Topics: Anxiety; Breast; Caffeine; Female; Humans; Mammography; Menopause; Menstrual Cycle; Middle Aged; Pai | 1991 |
Caffeine consumption in patients with eating disorders.
Topics: Adult; Alcohol Drinking; Anorexia Nervosa; Anxiety; Arousal; Bulimia; Caffeine; Dose-Response Relati | 1991 |
Caffeine-induced anxiety and increase of kynurenine concentration in plasma of healthy subjects: a pilot study.
Topics: Adolescent; Anxiety; Arousal; Caffeine; Humans; Kynurenine; Male; Pilot Projects | 1991 |
Caffeine consumption and anxiety and depressive symptomatology among medical students.
Topics: Adult; Alcohol Drinking; Anxiety; Caffeine; Chi-Square Distribution; Depression; Female; Humans; Jap | 1990 |
Validation of aversion towards open space and height as a measure of anxiety in the genetically based animal model of depression.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Depressive Disorder; Diazepam; Disease Models, Animal; | 1990 |
Factors related to treatment resistance in hypertension.
Topics: Antihypertensive Agents; Anxiety; Caffeine; Case-Control Studies; Drug Therapy, Combination; Female; | 1990 |
Malignant hyperthermia in the otolaryngologic patient: prospective anesthetic and surgical management of eight children.
Topics: Adenoidectomy; Anesthesia, General; Anxiety; Caffeine; Child; Child, Preschool; Contracture; Female; | 1990 |
Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors.
Topics: 2-Chloroadenosine; Adenosine; Alprazolam; Anxiety; Caffeine; Chlordiazepoxide; Clonidine; Flumazenil | 1989 |
Antagonistic effects of caffeine and yohimbine in animal tests of anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Conflict, Psychological; Drinking; Interpersonal Relat | 1989 |
Self-regulation of ICSS duration: effects of anxiogenic substances, benzodiazepine antagonists and antidepressants.
Topics: Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Benzodia | 1985 |
Caffeine reduction as an adjunct to anxiety management.
Topics: Adolescent; Adult; Aged; Anxiety; Caffeine; Combined Modality Therapy; Female; Humans; Male; Middle | 1988 |
Exercise-induced migraine prodrome symptoms.
Topics: Adult; Anxiety; Caffeine; Humans; Hypoglycemia; Male; Migraine Disorders; Physical Exertion | 1987 |
Potentiation of performance-induced anxiety by caffeine in coffee.
Topics: Anxiety; Caffeine; Female; Humans; Male; Stress, Psychological | 1986 |
Effects of tunnel maze complexity on caffeinic hyperactivity in the rat.
Topics: Animals; Anxiety; Caffeine; Environment; Exploratory Behavior; Female; Habituation, Psychophysiologi | 1985 |
Cyclic adenosine monophosphate phosphodiesterase in brain: effect on anxiety.
Topics: Animals; Anxiety; Barbiturates; Brain; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide | 1972 |