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caffeine and Aneuploid

caffeine has been researched along with Aneuploid in 15 studies

Research Excerpts

ExcerptRelevanceReference
"Most caffeine-treated mitotic cells showed misalignment of chromosomes at the metaphase plates, and were arrested at prometaphase."5.35Caffeine yields aneuploidy through asymmetrical cell division caused by misalignment of chromosomes. ( Imoto, I; Inazawa, J; Katsuki, Y; Mizutani, S; Nagasawa, M; Nakada, S; Yokoyama, T, 2008)
"Caffeine was significantly associated with increased frequencies of sperm aneuploidy XX18 and XY18, diploidy XY18-18 and the duplication phenotype YY18-18 controlling for alcohol, smoking and donor age."5.30Use of fluorescence in situ hybridization (FISH) to assess effects of smoking, caffeine, and alcohol on aneuploidy load in sperm of healthy men. ( Everson, RB; Robbins, WA; Truong, KY; Vine, MF, 1997)
"Sperm aneuploidy by multicolor fluorescence in situ hybridization for chromosomes 8, X, and Y; conventional semen analyses; computer-aided sperm analysis for motility; and sperm chromatin structure analysis."2.69Smoking cigarettes is associated with increased sperm disomy in teenage men. ( Evenson, D; Lowe, X; Moore, D; Perreault, S; Rubes, J; Selevan, SG; Slott, V; Wyrobek, AJ, 1998)
"Roberts syndrome is an autosomal recessive disorder characterised primarily by symmetric reduction of all limbs and growth retardation."1.32Recapitulation of the Roberts syndrome cellular phenotype by inhibition of INCENP, ZWINT-1 and ZW10 genes. ( Ascoli, C; Mariani, T; Montagna, C; Musio, A; Ried, T; Vezzoni, P; Zambroni, D, 2004)
"Caffeine was significantly associated with increased frequencies of sperm aneuploidy XX18 and XY18, diploidy XY18-18 and the duplication phenotype YY18-18 controlling for alcohol, smoking and donor age."1.30Use of fluorescence in situ hybridization (FISH) to assess effects of smoking, caffeine, and alcohol on aneuploidy load in sperm of healthy men. ( Everson, RB; Robbins, WA; Truong, KY; Vine, MF, 1997)
"Caffeine has also been reported to retard meiotic progression and induce aneuploidy in hamster oocytes in vitro."1.29Cytogenetic effects of caffeine during in vivo mouse oocyte maturation. ( London, SN; Mailhes, JB; Young, D, 1996)
"It may mean that caffeine also induces aneuploidy."1.27Sequence of centromere separation: kinetochore formation in induced laggards and micronuclei. ( Swearngin, SE; Vig, BK, 1986)
"Although aneuploidy is a serious human health problem, the experimental methodology devised until now to study the mechanisms involved in the induction of aneuploidy and for the screening of aneuploidy-inducing agents has not been so much employed to have the necessary validation."1.27A simple and reliable in vitro test system for the analysis of induced aneuploidy as well as other cytogenetic end-points using Chinese hamster cells. ( Dulout, FN; Natarajan, AT, 1987)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's7 (46.67)18.2507
2000's3 (20.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Katsuki, Y1
Nakada, S1
Yokoyama, T1
Imoto, I1
Inazawa, J1
Nagasawa, M1
Mizutani, S1
Chen, P1
O'Neal, JF1
Ebelt, ND1
Cantrell, MA1
Mitra, S1
Nasrazadani, A1
Vandenbroek, TL1
Heasley, LE1
Van Den Berg, CL1
Robbins, WA2
Musio, A1
Mariani, T1
Montagna, C1
Zambroni, D1
Ascoli, C1
Ried, T1
Vezzoni, P1
Mailhes, JB1
Young, D1
London, SN1
Vine, MF1
Truong, KY1
Everson, RB1
Vig, BK2
Henderson, A1
Rubes, J1
Lowe, X1
Moore, D1
Perreault, S1
Slott, V1
Evenson, D1
Selevan, SG1
Wyrobek, AJ1
Burns, EM1
Christopoulou, L1
Corish, P1
Tyler-Smith, C1
Hervás, JP1
Giménez-Martín, G1
Panzera, F1
Cánovas, JL1
de la Torre, C1
López-Sáez, JF1
Zinkowski, RP2
McCune, SL2
Balczon, RD2
Rao, PN2
Brinkley, BR2
Swearngin, SE1
Dulout, FN1
Natarajan, AT1

Reviews

1 review available for caffeine and Aneuploid

ArticleYear
FISH (fluorescence in situ hybridization) to detect effects of smoking, caffeine, and alcohol on human sperm chromosomes.
    Advances in experimental medicine and biology, 2003, Volume: 518

    Topics: Alcohol Drinking; Aneuploidy; Caffeine; Chromosomes; Humans; In Situ Hybridization, Fluorescence; Ma

2003

Trials

1 trial available for caffeine and Aneuploid

ArticleYear
Smoking cigarettes is associated with increased sperm disomy in teenage men.
    Fertility and sterility, 1998, Volume: 70, Issue:4

    Topics: Adolescent; Alcohol Drinking; Aneuploidy; Caffeine; Chromatin; Humans; In Situ Hybridization, Fluore

1998

Other Studies

13 other studies available for caffeine and Aneuploid

ArticleYear
Caffeine yields aneuploidy through asymmetrical cell division caused by misalignment of chromosomes.
    Cancer science, 2008, Volume: 99, Issue:8

    Topics: Aneuploidy; Caffeine; Cell Division; Chromosomes; Fluorescent Antibody Technique; HeLa Cells; Humans

2008
Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model.
    PloS one, 2010, May-03, Volume: 5, Issue:5

    Topics: Aneuploidy; Animals; Antigens, Polyomavirus Transforming; Caffeine; Cell Death; Chromosomal Proteins

2010
Recapitulation of the Roberts syndrome cellular phenotype by inhibition of INCENP, ZWINT-1 and ZW10 genes.
    Gene, 2004, Apr-28, Volume: 331

    Topics: Abnormalities, Multiple; Aneuploidy; Caffeine; Cell Cycle; Cell Division; Cell Line; Centromere; Chr

2004
Cytogenetic effects of caffeine during in vivo mouse oocyte maturation.
    Mutagenesis, 1996, Volume: 11, Issue:4

    Topics: Aneuploidy; Animals; Caffeine; Cricetinae; Cytogenetics; Female; In Vitro Techniques; Metaphase; Mic

1996
Use of fluorescence in situ hybridization (FISH) to assess effects of smoking, caffeine, and alcohol on aneuploidy load in sperm of healthy men.
    Environmental and molecular mutagenesis, 1997, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Alcohol Drinking; Aneuploidy; Caffeine; Cross-Sectional Studies; Diploidy; Humans

1997
Aneuploidy in male Indian muntjac cells is limited to the Y2 chromosome.
    Mutagenesis, 1998, Volume: 13, Issue:1

    Topics: Aneuploidy; Animals; Anthelmintics; Benomyl; Caffeine; Cell Line; Centromere; Colchicine; Gout Suppr

1998
Quantitative measurement of mammalian chromosome mitotic loss rates using the green fluorescent protein.
    Journal of cell science, 1999, Volume: 112 ( Pt 16)

    Topics: Aneuploidy; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Buffers; Caffeine; Ce

1999
Multinucleate plant cells. I. Aneuploidy in a proliferating population.
    Experimental cell research, 1976, Volume: 97

    Topics: Aneuploidy; Caffeine; Cell Division; Cell Nucleus; Cytological Techniques; Hexachlorocyclohexane; Mi

1976
A limited number of chromosomes makes a nucleus competent to respond to inducers of replication and mitosis in a plant.
    European journal of cell biology, 1992, Volume: 58, Issue:1

    Topics: Allium; Aneuploidy; Caffeine; Cell Nucleus; Chromosomes; DNA Replication; Mitosis; Probability

1992
The centromere and aneuploidy: II. Drug induced detachment and fragmentation of kinetochores of mammalian chromosomes.
    Progress in clinical and biological research, 1990, Volume: 340B

    Topics: Aneuploidy; Animals; Artiodactyla; Caffeine; Cell Division; Cell Line; Centromere; Chromosomes; Cric

1990
Sequence of centromere separation: kinetochore formation in induced laggards and micronuclei.
    Mutagenesis, 1986, Volume: 1, Issue:6

    Topics: Aneuploidy; Animals; Antibodies, Antinuclear; Benzimidazoles; Binding Sites, Antibody; Bisbenzimidaz

1986
The centromere and aneuploidy: I. Caffeine-induced detachment and fragmentation of kinetochores of mammalian chromosomes.
    Progress in clinical and biological research, 1989, Volume: 318

    Topics: Aneuploidy; Animals; Caffeine; Centromere; Chromosome Aberrations; Chromosomes; Cricetinae; DNA; Flo

1989
A simple and reliable in vitro test system for the analysis of induced aneuploidy as well as other cytogenetic end-points using Chinese hamster cells.
    Mutagenesis, 1987, Volume: 2, Issue:2

    Topics: Anaphase; Aneuploidy; Animals; Caffeine; Cells, Cultured; Chromosome Aberrations; Cytogenetics; Diet

1987