Page last updated: 2024-10-24

caffeine and Anankastic Personality

caffeine has been researched along with Anankastic Personality in 5 studies

Research Excerpts

ExcerptRelevanceReference
"Two small, double-blind, placebo-controlled, single-dose, crossover studies found dextroamphetamine (d-amphetamine) 30 mg clearly superior to placebo in relieving symptoms of obsessive-compulsive disorder (OCD)."9.14Double-blind study of dextroamphetamine versus caffeine augmentation for treatment-resistant obsessive-compulsive disorder. ( Aboujaoude, E; Gamel, NN; Koran, LM, 2009)
"Two small, double-blind, placebo-controlled, single-dose, crossover studies found dextroamphetamine (d-amphetamine) 30 mg clearly superior to placebo in relieving symptoms of obsessive-compulsive disorder (OCD)."5.14Double-blind study of dextroamphetamine versus caffeine augmentation for treatment-resistant obsessive-compulsive disorder. ( Aboujaoude, E; Gamel, NN; Koran, LM, 2009)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Mitra, S1
Santana Miranda, V1
McMillan, C1
Dykes, D1
Mucha, M1
Marth, TE1
Poe, B1
Basu, DG1
Bult-Ito, A1
M Koran, L1
Aboujaoude, E2
Koran, LM1
Gamel, NN1
LUNDERQUIST, B1
MacNeal, PS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind Trial of Acute and Intermediate-term Dextro-amphetamine Versus Caffeine Augmentation in Treatment Resistant Obsessive Compulsive Disorder (OCD)[NCT00363298]24 participants (Actual)Interventional2006-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Subjects With Clinical Global Impressions Scale - Improvement (CGI-I) Score of 1 or 2

Clinical Global Impressions Scale Improvement Score = 1 (very much improved), or 2 (much improved). Additional possible scale scores are 3 (minimally improved), 4 (no change), 5 (minimally worse), 6 (much worse) and 7 (very much worse). (NCT00363298)
Timeframe: At end of week 5, except 1 d-amphetamine subject rated at end of week 2

Interventionparticipants (Number)
D-amphetamine6
Caffeine Pills7

Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) Score

"Yale-Brown Obsessive-Compulsive Scale score by blinded investigator in direct interview. The scale score is the sum of ten items (5 for obsessions and 5 for compulsions: time occupied, degree of interference with functioning, degree of distress, effort to resist the symptom, success in resisting), each rated from 0 to 4, with higher scores indicating more severe OCD. Maximum score is 40. Scores of 14 and below are often described as subclinical, though patients with these scores may still exhibit troubling symptoms and mild to moderate distress. A total score of 8 or less is often termed remission. A decrease in total score from baseline to endpoint of either 25% or 35% is often used as a responder criterion in clinical trials." (NCT00363298)
Timeframe: At end of week 5, except 1 d-amphetamine subject rated at end of week 2

Interventionunits on a scale (Mean)
D-amphetamine13.3
Caffeine Pills13.0

Reviews

1 review available for caffeine and Anankastic Personality

ArticleYear
Promising Treatments for Obsessive-Compulsive Disorder: A Call for Additional Research.
    Current medicinal chemistry, 2018, Volume: 25, Issue:41

    Topics: Caffeine; Cognitive Behavioral Therapy; Combined Modality Therapy; Humans; Ketamine; Memantine; Obse

2018

Trials

1 trial available for caffeine and Anankastic Personality

ArticleYear
Double-blind study of dextroamphetamine versus caffeine augmentation for treatment-resistant obsessive-compulsive disorder.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:11

    Topics: Adult; Caffeine; Dextroamphetamine; Diagnostic and Statistical Manual of Mental Disorders; Double-Bl

2009

Other Studies

3 other studies available for caffeine and Anankastic Personality

ArticleYear
Trait specific modulatory effects of caffeine exposure on compulsive-like behaviors in a spontaneous mouse model of obsessive-compulsive disorder.
    Behavioural pharmacology, 2020, Volume: 31, Issue:7

    Topics: Animals; Animals, Outbred Strains; Anxiety; Caffeine; Central Nervous System Stimulants; Disease Mod

2020
[TRIAL OF SINEDYL WITH NEUROTIC PATIENTS IN GENERAL PRACTICE].
    Svenska lakartidningen, 1964, May-27, Volume: 61

    Topics: Anxiety; Anxiety Disorders; Atropa belladonna; Biomedical Research; Caffeine; General Practice; Huma

1964
The patient with headache.
    Postgraduate medicine, 1967, Volume: 42, Issue:4

    Topics: Age Factors; Alkaloids; Atropa belladonna; Caffeine; Diagnosis, Differential; Ergotamine; Headache;

1967