Page last updated: 2024-10-24

caffeine and Amentia

caffeine has been researched along with Amentia in 27 studies

Research Excerpts

ExcerptRelevanceReference
"Epidemiologic studies have provided inconclusive evidence for a protective effect of caffeine consumption on risk of dementia and cognitive decline."9.05Associations Between Caffeine Consumption, Cognitive Decline, and Dementia: A Systematic Review. ( Chen, JQA; Groot, C; Ossenkoppele, R; Scheltens, P, 2020)
" Studies were included when they: i) investigated patients diagnosed with dementia, ii) reported neuropsychiatric symptoms, iii) used caffeine or coffee consumption as an intervention, and iv) reported associations between caffeine or coffee consumption and neuropsychiatric symptoms."9.01Caffeine and neuropsychiatric symptoms in patients with dementia: A systematic review. ( Achterberg, WP; Giltay, E; Kromhout, MA; Numans, ME; Rius Ottenheim, N, 2019)
" We conducted a systematic review and meta-analysis of published studies quantifying the relation between caffeine intake and cognitive decline or dementia."8.86Caffeine intake and dementia: systematic review and meta-analysis. ( Costa, J; Lunet, N; Santos, C; Santos, J; Vaz-Carneiro, A, 2010)
" This review explores the relation between caffeine intake, diabetes, cognition and dementia, focusing on type 2 diabetes (T2DM)."8.86Caffeine, diabetes, cognition, and dementia. ( Biessels, GJ, 2010)
"Coffee, green tea, and caffeine are potential preventive factors for dementia, but the underlying evidence is insufficient."8.02Association of coffee, green tea, and caffeine with the risk of dementia in older Japanese people. ( Iki, M; Kabasawa, K; Kitamura, K; Kobayashi, R; Matsushita, N; Nakamura, K; Nakanishi, Y; Oshiki, R; Saito, T; Sasaki, A; Takachi, R; Takahashi, A; Tsugane, S; Watanabe, K; Watanabe, Y; Yamazaki, O, 2021)
"Caffeine is known to improve concentration and reduce fatigue in healthy adults, but high doses may induce anxiety and agitation."7.80Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study. ( Achterberg, WP; Jongerling, J; Kromhout, MA, 2014)
" Since caffeine (an adenosine receptor antagonist) and selective antagonists of adenosine A2A receptors modify the course of memory impairment in different amyloid-β-based experimental models of AD, we now tested the impact of caffeine on STZ-induced dementia and associated neurodegeneration in the hippocampus as well as on the expression and density of adenosine receptors."7.79Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A2A receptors upregulation in the hippocampus of a rat model of sporadic dementia. ( Costa, MS; Cunha, RA; Espinosa, J; Kalinine, E; Kazlauckas, V; Nunes, F; Porciúncula, LO; Rocha, A; Schein, V; Souza, DO, 2013)
" In particular, several cross-sectional and longitudinal population-based studies suggested a protective effect of coffee, tea, and caffeine use against late-life cognitive impairment/decline, although the association was not found in all cognitive domains investigated and there was a lack of a distinct dose-response association, with a stronger effect among women than men."6.52Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review. ( Barulli, MR; Bonfiglio, C; Guerra, V; Logroscino, G; Osella, A; Panza, F; Pilotto, A; Sabbà, C; Seripa, D; Solfrizzi, V, 2015)
"Caffeine has well-known short-term stimulating effects on central nervous system, but the long-term impacts on cognition have been less clear."5.36Caffeine as a protective factor in dementia and Alzheimer's disease. ( Eskelinen, MH; Kivipelto, M, 2010)
"We report that performance on neuropsychological tests used in the diagnosis of dementia can be influenced by external factors such as time of day (TOD) and caffeine."5.20Time of day and caffeine influence some neuropsychological tests in the elderly. ( Lesk, VE; Walters, ER, 2015)
"Epidemiologic studies have provided inconclusive evidence for a protective effect of caffeine consumption on risk of dementia and cognitive decline."5.05Associations Between Caffeine Consumption, Cognitive Decline, and Dementia: A Systematic Review. ( Chen, JQA; Groot, C; Ossenkoppele, R; Scheltens, P, 2020)
"This paper reports the results of a double blind study in patients with senile dementia to determine if the quality and quantity of sleep could be changed with various amounts of caffeine."5.04Caffeine in the "sundown syndrome." Report of negative results. ( Ginsburg, R; Weintraub, M, 1976)
" Studies were included when they: i) investigated patients diagnosed with dementia, ii) reported neuropsychiatric symptoms, iii) used caffeine or coffee consumption as an intervention, and iv) reported associations between caffeine or coffee consumption and neuropsychiatric symptoms."5.01Caffeine and neuropsychiatric symptoms in patients with dementia: A systematic review. ( Achterberg, WP; Giltay, E; Kromhout, MA; Numans, ME; Rius Ottenheim, N, 2019)
"Observational epidemiological studies such as cross-sectional, case-control, and cohort studies have reported inconsistent findings regarding the association between caffeine intake from coffee or tea and the risk of cognitive disorders such as dementia, Alzheimer's disease, cognitive impairment, and cognitive decline."4.91Caffeine intake from coffee or tea and cognitive disorders: a meta-analysis of observational studies. ( Kim, YS; Kwak, SM; Myung, SK, 2015)
" We conducted a systematic review and meta-analysis of published studies quantifying the relation between caffeine intake and cognitive decline or dementia."4.86Caffeine intake and dementia: systematic review and meta-analysis. ( Costa, J; Lunet, N; Santos, C; Santos, J; Vaz-Carneiro, A, 2010)
" This review explores the relation between caffeine intake, diabetes, cognition and dementia, focusing on type 2 diabetes (T2DM)."4.86Caffeine, diabetes, cognition, and dementia. ( Biessels, GJ, 2010)
"Coffee, green tea, and caffeine are potential preventive factors for dementia, but the underlying evidence is insufficient."4.02Association of coffee, green tea, and caffeine with the risk of dementia in older Japanese people. ( Iki, M; Kabasawa, K; Kitamura, K; Kobayashi, R; Matsushita, N; Nakamura, K; Nakanishi, Y; Oshiki, R; Saito, T; Sasaki, A; Takachi, R; Takahashi, A; Tsugane, S; Watanabe, K; Watanabe, Y; Yamazaki, O, 2021)
"Caffeine is known to improve concentration and reduce fatigue in healthy adults, but high doses may induce anxiety and agitation."3.80Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study. ( Achterberg, WP; Jongerling, J; Kromhout, MA, 2014)
" Since caffeine (an adenosine receptor antagonist) and selective antagonists of adenosine A2A receptors modify the course of memory impairment in different amyloid-β-based experimental models of AD, we now tested the impact of caffeine on STZ-induced dementia and associated neurodegeneration in the hippocampus as well as on the expression and density of adenosine receptors."3.79Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A2A receptors upregulation in the hippocampus of a rat model of sporadic dementia. ( Costa, MS; Cunha, RA; Espinosa, J; Kalinine, E; Kazlauckas, V; Nunes, F; Porciúncula, LO; Rocha, A; Schein, V; Souza, DO, 2013)
"To examine the association between caffeine intake, cognitive decline, and incident dementia in a community-based sample of subjects aged 65 years and over."3.74The neuroprotective effects of caffeine: a prospective population study (the Three City Study). ( Ancelin, ML; Barberger-Gateau, P; Carrière, I; Dartigues, JF; de Mendonca, A; Portet, F; Ritchie, K; Rouaud, O, 2007)
" In particular, several cross-sectional and longitudinal population-based studies suggested a protective effect of coffee, tea, and caffeine use against late-life cognitive impairment/decline, although the association was not found in all cognitive domains investigated and there was a lack of a distinct dose-response association, with a stronger effect among women than men."2.52Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review. ( Barulli, MR; Bonfiglio, C; Guerra, V; Logroscino, G; Osella, A; Panza, F; Pilotto, A; Sabbà, C; Seripa, D; Solfrizzi, V, 2015)
"Caffeine intake was determined according to self-reported coffee, tea, and cola consumption at baseline."1.37Coffee intake in midlife and risk of dementia and its neuropathologic correlates. ( Gelber, RP; Masaki, KH; Petrovitch, H; Ross, GW; White, LR, 2011)
"Caffeine has well-known short-term stimulating effects on central nervous system, but the long-term impacts on cognition have been less clear."1.36Caffeine as a protective factor in dementia and Alzheimer's disease. ( Eskelinen, MH; Kivipelto, M, 2010)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's0 (0.00)18.2507
2000's1 (3.70)29.6817
2010's20 (74.07)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Matsushita, N1
Nakanishi, Y1
Watanabe, Y1
Kitamura, K1
Kabasawa, K1
Takahashi, A1
Saito, T1
Kobayashi, R1
Takachi, R1
Oshiki, R1
Tsugane, S1
Iki, M1
Sasaki, A1
Yamazaki, O1
Watanabe, K1
Nakamura, K1
Kromhout, M3
Chen, JQA1
Scheltens, P1
Groot, C1
Ossenkoppele, R1
Kromhout, MA3
van Eijk, M1
Pieper, MJC1
Chel, VGM1
Achterberg, WP3
Numans, ME2
Dominguez, LJ1
Barbagallo, M1
Park, J1
Han, JW1
Lee, JR1
Byun, S1
Suh, SW1
Kim, T1
Yoon, IY1
Kim, KW1
Gilbert, N1
Rius Ottenheim, N1
Giltay, E1
Carroll, VS1
Jongerling, J1
Beydoun, MA1
Beydoun, HA1
Gamaldo, AA1
Teel, A1
Zonderman, AB1
Wang, Y1
Walters, ER1
Lesk, VE1
Kim, YS1
Kwak, SM1
Myung, SK1
Panza, F1
Solfrizzi, V1
Barulli, MR1
Bonfiglio, C1
Guerra, V1
Osella, A1
Seripa, D1
Sabbà, C1
Pilotto, A1
Logroscino, G1
Golden, LE1
Sassoon, P1
Cáceda, R1
Soraoka, H1
Oniki, K1
Matsuda, K1
Ono, T1
Taharazako, K1
Uchiyashiki, Y1
Kamihashi, R1
Kita, A1
Takashima, A1
Nakagawa, K1
Yasui-Furukori, N1
Kadowaki, D1
Miyata, K1
Saruwatari, J1
Morris, MC1
Santos, C1
Costa, J1
Santos, J1
Vaz-Carneiro, A1
Lunet, N1
Biessels, GJ1
Eskelinen, MH1
Kivipelto, M1
Gelber, RP1
Petrovitch, H1
Masaki, KH1
Ross, GW1
White, LR1
Cao, C1
Loewenstein, DA1
Lin, X1
Zhang, C1
Wang, L1
Duara, R1
Wu, Y1
Giannini, A1
Bai, G1
Cai, J1
Greig, M1
Schofield, E1
Ashok, R1
Small, B1
Potter, H1
Arendash, GW1
Espinosa, J1
Rocha, A1
Nunes, F1
Costa, MS1
Schein, V1
Kazlauckas, V1
Kalinine, E1
Souza, DO1
Cunha, RA1
Porciúncula, LO1
Ritchie, K1
Carrière, I1
de Mendonca, A1
Portet, F1
Dartigues, JF1
Rouaud, O1
Barberger-Gateau, P1
Ancelin, ML1
Schelling, JL1
Ginsburg, R1
Weintraub, M1
Kaiser, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Vitamin D Status and Intakes and Their Association With Cognitive Trajectory in a Longitudinal Study of Urban Adults[NCT03320109]3,720 participants (Actual)Observational2004-08-18Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for caffeine and Amentia

ArticleYear
Associations Between Caffeine Consumption, Cognitive Decline, and Dementia: A Systematic Review.
    Journal of Alzheimer's disease : JAD, 2020, Volume: 78, Issue:4

    Topics: Caffeine; Coffee; Cognitive Dysfunction; Dementia; Humans; Protective Factors; Sex Factors; Tea

2020
Nutritional prevention of cognitive decline and dementia.
    Acta bio-medica : Atenei Parmensis, 2018, 06-07, Volume: 89, Issue:2

    Topics: Antioxidants; Autophagy; Caffeine; Catechin; Central Nervous System Stimulants; Chocolate; Cognitive

2018
Caffeine and neuropsychiatric symptoms in patients with dementia: A systematic review.
    Experimental gerontology, 2019, 07-15, Volume: 122

    Topics: Apathy; Caffeine; Dementia; Humans; Motor Skills; Nursing Homes; Randomized Controlled Trials as Top

2019
Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis.
    BMC public health, 2014, Jun-24, Volume: 14

    Topics: Alcohol Drinking; Alzheimer Disease; Antioxidants; Caffeine; Cognition; Cognition Disorders; Dementi

2014
Caffeine intake from coffee or tea and cognitive disorders: a meta-analysis of observational studies.
    Neuroepidemiology, 2015, Volume: 44, Issue:1

    Topics: Alzheimer Disease; Caffeine; Case-Control Studies; Coffee; Cognition Disorders; Cohort Studies; Deme

2015
Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review.
    The journal of nutrition, health & aging, 2015, Volume: 19, Issue:3

    Topics: Alzheimer Disease; Caffeine; Coffee; Cognition; Cognition Disorders; Cognitive Dysfunction; Dementia

2015
Caffeine intake and dementia: systematic review and meta-analysis.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20 Suppl 1

    Topics: Caffeine; Case-Control Studies; Central Nervous System Stimulants; Cohort Studies; Cross-Sectional S

2010
Caffeine, diabetes, cognition, and dementia.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20 Suppl 1

    Topics: Animals; Caffeine; Central Nervous System Stimulants; Coffee; Cognition Disorders; Dementia; Diabete

2010
[Therapy of sleep disorders in old age].
    Medizinische Klinik, 1972, Dec-15, Volume: 67, Issue:50

    Topics: Age Factors; Butyrophenones; Caffeine; Cardiac Glycosides; Cerebrovascular Disorders; Chlormethiazol

1972

Trials

2 trials available for caffeine and Amentia

ArticleYear
Time of day and caffeine influence some neuropsychological tests in the elderly.
    Psychological assessment, 2015, Volume: 27, Issue:1

    Topics: Aged; Alzheimer Disease; Caffeine; Circadian Rhythm; Dementia; Female; Humans; Male; Neuropsychologi

2015
Caffeine in the "sundown syndrome." Report of negative results.
    Journal of gerontology, 1976, Volume: 31, Issue:4

    Topics: Aged; Caffeine; Clinical Trials as Topic; Dementia; Humans; Placebos; Sleep

1976

Other Studies

16 other studies available for caffeine and Amentia

ArticleYear
Association of coffee, green tea, and caffeine with the risk of dementia in older Japanese people.
    Journal of the American Geriatrics Society, 2021, Volume: 69, Issue:12

    Topics: Adult; Aged; Beverages; Caffeine; Coffee; Cohort Studies; Dementia; Diet Surveys; Female; Follow-Up

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
    Tijdschrift voor gerontologie en geriatrie, 2021, 09-21, Volume: 52, Issue:4

    Topics: Caffeine; Dementia; Humans; Problem Behavior

2021
BeCaf study: caffeine and behaviour in nursing homes, a study protocol and EBM training program.
    The Netherlands journal of medicine, 2018, Volume: 76, Issue:3

    Topics: Aged; Caffeine; Clinical Protocols; Cohort Studies; Curriculum; Dementia; Diabetes Mellitus; Educati

2018
Lifetime coffee consumption, pineal gland volume, and sleep quality in late life.
    Sleep, 2018, 10-01, Volume: 41, Issue:10

    Topics: Aged; Aged, 80 and over; Caffeine; Coffee; Cognition; Dementia; Female; Humans; Imaging, Three-Dimen

2018
The science of tea's mood-altering magic.
    Nature, 2019, Volume: 566, Issue:7742

    Topics: Adenosine; Affect; Alpha Rhythm; Animals; Antioxidants; Behavior; Beta Rhythm; Blood-Brain Barrier;

2019
In praise of coffee ... and caffeine.
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 2013, Volume: 45, Issue:5

    Topics: Animals; Caffeine; Central Nervous System Stimulants; Coffee; Dementia; Humans; Mice; Neoplasms; Spe

2013
Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study.
    The journal of nutrition, health & aging, 2014, Volume: 18, Issue:4

    Topics: Aged, 80 and over; Anxiety; Apathy; Behavioral Symptoms; Caffeine; Dementia; Female; Humans; Male; M

2014
A case report of late onset psychosis with dementia and aspirin and caffeine addiction.
    Schizophrenia research, 2015, Volume: 168, Issue:1-2

    Topics: Age of Onset; Aspirin; Caffeine; Central Nervous System Agents; Dementia; Diagnosis, Differential; H

2015
The Effect of Yokukansan, a Traditional Herbal Preparation Used for the Behavioral and Psychological Symptoms of Dementia, on the Drug-Metabolizing Enzyme Activities in Healthy Male Volunteers.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:9

    Topics: Adult; Arylamine N-Acetyltransferase; Behavior; Caffeine; Cytochrome P-450 Enzyme System; Dementia;

2016
Caffeine Intake and Dementia Risk-A Health Benefit From One of Life's Simple Pleasures?
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2016, Volume: 71, Issue:12

    Topics: Caffeine; Dementia; Humans; Pleasure; Risk Factors

2016
Caffeine as a protective factor in dementia and Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20 Suppl 1

    Topics: Aged; Alzheimer Disease; Caffeine; Cardiovascular Diseases; Central Nervous System Stimulants; Coffe

2010
Coffee intake in midlife and risk of dementia and its neuropathologic correlates.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 23, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Asian; Brain; Caffeine; Case-Control Studie

2011
High Blood caffeine levels in MCI linked to lack of progression to dementia.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Caffeine; Case-Control Studies; Cognition; Cognitive Dys

2012
Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A2A receptors upregulation in the hippocampus of a rat model of sporadic dementia.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 34, Issue:2

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Caffeine; Dementia; Disease Models, Animal; Hippoc

2013
The neuroprotective effects of caffeine: a prospective population study (the Three City Study).
    Neurology, 2007, Aug-07, Volume: 69, Issue:6

    Topics: Aged; Aged, 80 and over; Agnosia; AIDS Arteritis, Central Nervous System; Amyloid beta-Peptides; Caf

2007
[Drug treatment of cerebral disorders in senility].
    Therapeutische Umschau. Revue therapeutique, 1982, Volume: 39, Issue:11

    Topics: Aged; Alzheimer Disease; Amphetamines; Biotransformation; Caffeine; Dementia; Humans; Middle Aged; V

1982