Page last updated: 2024-10-24

caffeine and Adverse Drug Event

caffeine has been researched along with Adverse Drug Event in 48 studies

Research Excerpts

ExcerptRelevanceReference
" We prospectively compared the safety profile of ECC and LP in preterm infants with apnea of prematurity."7.80Safety profile comparison between extemporaneous and a licensed preparation of caffeine citrate in preterm infants with apnea of prematurity. ( Arand, J; Engel, C; Poets, CF; Vatlach, S, 2014)
"A spectrum of adverse drug reactions that are caused by the combined action of drugs and viruses has been described: ampicillin rash in acute infectious mononucleosis; Reye's syndrome; hypersensitivity reactions to sulphonamides in patients with HIV infection; drug-induced agranulocytosis; paracetamol (acetaminophen) hepatotoxicity; aspirin (acetylsalicyclic acid)-induced asthma; Epstein-Barr virus-associated lymphoma and methotrexate; and AIDS-related Kaposi's sarcoma and nitrite use."4.79Role of viral infections in the induction of adverse drug reactions. ( Levy, M, 1997)
" We prospectively compared the safety profile of ECC and LP in preterm infants with apnea of prematurity."3.80Safety profile comparison between extemporaneous and a licensed preparation of caffeine citrate in preterm infants with apnea of prematurity. ( Arand, J; Engel, C; Poets, CF; Vatlach, S, 2014)
"PO caffeine was inferior to IV aminophylline for CR + PRE."2.84Aminophylline and caffeine for reversal of adverse symptoms associated with regadenoson SPECT MPI. ( Doran, JA; Gupta, R; Mackin, ML; Sajjad, W; Schneider, MD; Schwartz, RG, 2017)
"Caffeine was given at least 3 minutes after tracer injection."1.91Buccal caffeine strips for reversal of adverse symptoms of vasodilator stress. ( Abdulla, KH; Bote, J; Doran, JA; Duvall, WL; Elsadany, M; Schwartz, RG; Stringer, B, 2023)
"To describe and compare caffeinated energy drink adverse event (AE) report/exposure call data from the US Food and Drug Administration Center for Food Safety and Applied Nutrition's Adverse Event Reporting System (CAERS) and the American Association of Poison Control Centers' National Poison Data System (NPDS)."1.51Caffeinated energy drinks: adverse event reports to the US Food and Drug Administration and the National Poison Data System, 2008 to 2015. ( Jones, OE; Lurie, P; Markon, AO; Punzalan, CM; Wolpert, B, 2019)
" Extracts of Athrixia phylicoides and Athrixia elata were tested for toxic effects to brine shrimp larvae and the Vero kidney cell line."1.34Evaluation of Athrixia bush tea for cytotoxicity, antioxidant activity, caffeine content and presence of pyrrolizidine alkaloids. ( Eloff, JN; McGaw, LJ; Steenkamp, V, 2007)
" A dose-response to varying concentrations of bitter tastants can be measured."1.30Response of pigs to bitter-tasting compounds. ( Nelson, SL; Sanregret, JD, 1997)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199020 (41.67)18.7374
1990's5 (10.42)18.2507
2000's3 (6.25)29.6817
2010's14 (29.17)24.3611
2020's6 (12.50)2.80

Authors

AuthorsStudies
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Elsadany, M1
Stringer, B1
Bote, J1
Abdulla, KH1
Doran, JA2
Schwartz, RG2
Duvall, WL1
Silva Maldonado, P1
Ramírez Moreno, E1
Arias Rico, J1
Fernández Cortés, TL1
Costantino, A1
Maiese, A1
Lazzari, J1
Casula, C1
Turillazzi, E1
Frati, P1
Fineschi, V1
Ghannoum, M1
Hoffman, RS1
Roberts, DM1
Lavergne, V1
Nolin, TD1
Gosselin, S1
Kohl, B1
Kaur, K1
Dincher, N1
Schumann, J1
Carachilo, T1
Komurek, C1
Lieberman, HR1
Khan, M1
Butt, SA1
Krpo, M1
Arnestad, M1
Karinen, R1
David, PS1
Kling, JM1
Vegunta, S1
Faubion, SS1
Kapoor, E1
Mara, KC1
Schroeder, DR1
Hilsaca, KF1
Kuhle, CL1
Markon, AO1
Jones, OE1
Punzalan, CM1
Lurie, P1
Wolpert, B1
Vatlach, S1
Arand, J1
Engel, C1
Poets, CF1
Rowe, H1
Baker, T1
Hale, TW1
Timmins, MA1
Rosenberg, H1
Larach, MG1
Sterling, C1
Kraeva, N1
Riazi, S1
Mounier-Vehier, C1
Boudghène, F1
Claisse, G1
Delsart, P1
Sajjad, W1
Schneider, MD1
Gupta, R1
Mackin, ML1
Love, IY1
Perl, S1
Rapoport, MJ1
Grossman, E1
Messerli, FH1
Suzuki, J1
Nikko, H1
Kaiho, F1
Yamaguchi, K1
Wada, H1
Suzuki, M1
McGaw, LJ1
Steenkamp, V1
Eloff, JN1
Ouellet, N1
Morris, DL1
Lake, CR1
Tenglin, R1
Chernow, B1
Holloway, HC1
Lambert, GH1
Kotake, AN1
Schoeller, D1
Talafré, ML1
Seltzer, S1
Katsuragi, Y1
Sugiura, Y1
Lee, C1
Otsuji, K1
Kurihara, K1
Brown, SL1
Salive, ME1
Pahor, M1
Foley, DJ1
Corti, MC1
Langlois, JA1
Wallace, RB1
Harris, TB1
Levy, M1
Nelson, SL1
Sanregret, JD1
Shea, PE1
Koetting, JF1
Reus, VI1
Morrison, R1
Cooke, AR1
Weber, WW1
Hein, DW1
Leonard, TK1
Watson, RR1
Mohs, ME1
Kalow, W1
Spencer, H1
Kramer, L1
Mikuz, G1
Huber, C1
Födisch, HJ1
Propst, A1
Andersson, S1
Dökert, B1
Alter, HG1
Marks, V1
Boyd, EM1
Bulgarelli, R1
Silverman, A1

Reviews

11 reviews available for caffeine and Adverse Drug Event

ArticleYear
The Dark Side of Energy Drinks: A Comprehensive Review of Their Impact on the Human Body.
    Nutrients, 2023, Sep-09, Volume: 15, Issue:18

    Topics: Adolescent; Animals; Athletes; Caffeine; Drug-Related Side Effects and Adverse Reactions; Energy Dri

2023
Maternal medication, drug use, and breastfeeding.
    Child and adolescent psychiatric clinics of North America, 2015, Volume: 24, Issue:1

    Topics: Breast Feeding; Caffeine; Cotinine; Drug-Related Side Effects and Adverse Reactions; Ethanol; Female

2015
Drug-induced hypertension: an unappreciated cause of secondary hypertension.
    The American journal of medicine, 2012, Volume: 125, Issue:1

    Topics: Adrenal Cortex Hormones; Alcohol Drinking; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal;

2012
Psychomotor stimulant-induced mania in a genetically predisposed patient: a review of the literature and report of a case.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Caffeine; Drug Combinations; Drug-Related S

1983
The CO2 breath tests as monitors of the cytochrome P450 dependent mixed function monooxygenase system.
    Progress in clinical and biological research, 1983, Volume: 135

    Topics: Animals; Biotransformation; Breath Tests; Caffeine; Carbon Dioxide; Cytochrome P-450 Enzyme System;

1983
Foods, and food and drug combinations, responsible for head and neck pain.
    Cephalalgia : an international journal of headache, 1982, Volume: 2, Issue:2

    Topics: Adult; Alcoholic Beverages; Amygdalin; Cacao; Caffeine; Child; Chronic Disease; Cluster Headache; Dr

1982
Role of viral infections in the induction of adverse drug reactions.
    Drug safety, 1997, Volume: 16, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Agranulocytosis; Ampicillin; Caffeine; Drug-Related Side Effects

1997
Cancer of the urinary bladder - epidemiology and aetiology.
    Urological research, 1978, Volume: 6, Issue:4

    Topics: 2-Naphthylamine; Animals; Caffeine; Coffee; Drug-Related Side Effects and Adverse Reactions; Egypt;

1978
N-acetylation pharmacogenetics.
    Pharmacological reviews, 1985, Volume: 37, Issue:1

    Topics: Acebutolol; Acetyl Coenzyme A; Acetylation; Acetyltransferases; Aminoglutethimide; Animals; Anti-Anx

1985
The effects of caffeine on various body systems: a review.
    Journal of the American Dietetic Association, 1987, Volume: 87, Issue:8

    Topics: Adult; Animals; Beverages; Caffeine; Child; Drug-Related Side Effects and Adverse Reactions; Fetus;

1987
Ethnic differences in reactions to drugs and xenobiotics. Caffeine and other drugs.
    Progress in clinical and biological research, 1986, Volume: 214

    Topics: Acetylation; Caffeine; Cytochrome P-450 Enzyme System; Diphenhydramine; Drug-Related Side Effects an

1986

Trials

1 trial available for caffeine and Adverse Drug Event

ArticleYear
Aminophylline and caffeine for reversal of adverse symptoms associated with regadenoson SPECT MPI.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017, Volume: 24, Issue:3

    Topics: Administration, Oral; Aged; Aminophylline; Caffeine; Cardiotonic Agents; Causality; Drug Interaction

2017

Other Studies

36 other studies available for caffeine and Adverse Drug Event

ArticleYear
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Buccal caffeine strips for reversal of adverse symptoms of vasodilator stress.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2023, Volume: 30, Issue:2

    Topics: Aminophylline; Caffeine; Drug-Related Side Effects and Adverse Reactions; Exercise Test; Humans; Myo

2023
[Energy drink consumption patterns and its adverse effects on adolescent health.]
    Revista espanola de salud publica, 2022, Nov-03, Volume: 96

    Topics: Adolescent; Adolescent Health; Caffeine; Cross-Sectional Studies; Drug-Related Side Effects and Adve

2022
Hemodialysis removal of caffeine.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:6

    Topics: Caffeine; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Humans; Renal Dialysis

2020
The authors respond: Reporting novel treatments of life threatening ingestions.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:6

    Topics: Caffeine; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Humans; Poison Control Cen

2020
Why Are Certain Caffeine-Containing Products Associated With Serious Adverse Effects?
    Mayo Clinic proceedings, 2020, Volume: 95, Issue:8

    Topics: Caffeine; Drug-Related Side Effects and Adverse Reactions; Humans; United States; United States Food

2020
Adverse Effects of Caffeine on Development of Femur of BALB/c Mice and Protective Role of Vitamin D3.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2017, Volume: 27, Issue:7

    Topics: Animals; Caffeine; Cholecalciferol; Dose-Response Relationship, Drug; Drug-Related Side Effects and

2017
Determination of Acetaminophen, Dexchlorpheniramine, Caffeine, Cotinine and Salicylic acid in 100 μL of Whole Blood by UHPLC-MS/MS.
    Journal of analytical toxicology, 2018, Mar-01, Volume: 42, Issue:2

    Topics: Acetaminophen; Autopsy; Caffeine; Child, Preschool; Chlorpheniramine; Chromatography, High Pressure

2018
Vasomotor symptoms in women over 60: results from the Data Registry on Experiences of Aging, Menopause, and Sexuality (DREAMS).
    Menopause (New York, N.Y.), 2018, Volume: 25, Issue:10

    Topics: Aged; Anxiety; Caffeine; Cohort Studies; Cross-Sectional Studies; Drug-Related Side Effects and Adve

2018
Caffeinated energy drinks: adverse event reports to the US Food and Drug Administration and the National Poison Data System, 2008 to 2015.
    Public health nutrition, 2019, Volume: 22, Issue:14

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Caffeine; Centr

2019
Safety profile comparison between extemporaneous and a licensed preparation of caffeine citrate in preterm infants with apnea of prematurity.
    Neonatology, 2014, Volume: 105, Issue:2

    Topics: Apnea; Caffeine; Chemistry, Pharmaceutical; Citrates; Drug-Related Side Effects and Adverse Reaction

2014
Malignant hyperthermia testing in probands without adverse anesthetic reaction.
    Anesthesiology, 2015, Volume: 123, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Dantrolene; Drug-Related Side Effects an

2015
[Iatrogenic and drug-induced hypertension].
    La Revue du praticien, 2015, Volume: 65, Issue:6

    Topics: Alcohol Drinking; Caffeine; Central Nervous System Stimulants; Drug-Related Side Effects and Adverse

2015
A Rare Case of Caffeine Storm due to Excessive Coca-Cola Consumption.
    The Israel Medical Association journal : IMAJ, 2016, Volume: 18, Issue:6

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Diabetic Ketoacidosis; Diagnosis, Differential;

2016
[The problems of multiple-chemical sensitivity patients in using medicinal drugs].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2004, Volume: 124, Issue:8

    Topics: Adult; Aspirin; Caffeine; Contraindications; Drug Hypersensitivity; Drug-Related Side Effects and Ad

2004
Evaluation of Athrixia bush tea for cytotoxicity, antioxidant activity, caffeine content and presence of pyrrolizidine alkaloids.
    Journal of ethnopharmacology, 2007, Mar-01, Volume: 110, Issue:1

    Topics: Animals; Antioxidants; Artemia; Beverages; Caffeine; Cell Line; Drug-Related Side Effects and Advers

2007
Sleep satisfaction of older adults living in the community: identifying associated behavioral and health factors.
    Journal of gerontological nursing, 2006, Volume: 32, Issue:10

    Topics: Aged; Anxiety; Attitude to Health; Caffeine; Cross-Sectional Studies; Depression; Drug-Related Side

2006
[Interference between fetal distress and administration of drugs].
    Soins. Gynecologie, obstetrique, puericulture, pediatrie, 1983, Issue:20

    Topics: Alcohol Drinking; Caffeine; Drug-Related Side Effects and Adverse Reactions; Female; Fetal Distress;

1983
Selective inhibition of bitter taste of various drugs by lipoprotein.
    Pharmaceutical research, 1995, Volume: 12, Issue:5

    Topics: Caffeine; Chemistry, Pharmaceutical; Drug Interactions; Drug-Related Side Effects and Adverse Reacti

1995
Occult caffeine as a source of sleep problems in an older population.
    Journal of the American Geriatrics Society, 1995, Volume: 43, Issue:8

    Topics: Aged; Caffeine; Cross-Sectional Studies; Diet Surveys; Drug-Related Side Effects and Adverse Reactio

1995
Response of pigs to bitter-tasting compounds.
    Chemical senses, 1997, Volume: 22, Issue:2

    Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions

1997
Drug- and caffeine-induced headaches.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1997, Sep-01, Volume: 157, Issue:5

    Topics: Caffeine; Drug-Related Side Effects and Adverse Reactions; Headache; Humans; Migraine Disorders

1997
The use of drugs for behavior modification as it relates to the practice of optometry--Part II.
    Journal of the American Optometric Association, 1977, Volume: 48, Issue:2

    Topics: Analgesics, Opioid; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agent

1977
Behavioral side effects of medical drugs.
    Primary care, 1979, Volume: 6, Issue:2

    Topics: Adrenal Cortex Hormones; Aged; Antihypertensive Agents; Antitubercular Agents; Aspirin; Behavior; Ca

1979
Drugs and gastric damage.
    Drugs, 1976, Volume: 11, Issue:1

    Topics: Adrenal Cortex Hormones; Aspirin; Buffers; Caffeine; Drug Compounding; Drug-Related Side Effects and

1976
NIH Consensus Conference: osteoporosis. Factors contributing to osteoporosis.
    The Journal of nutrition, 1986, Volume: 116, Issue:2

    Topics: Aged; Alcohol Drinking; Animals; Caffeine; Calcium; Calcium, Dietary; Diet; Drug-Related Side Effect

1986
[Cytophatometric and autoradiographic studies of the proliferation of hemopoetic bone-marrow cells in medicamentous induced panmyelopathy (author's transl)].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1972, Volume: 56

    Topics: Adolescent; Adult; Aminopyrine; Autoradiography; Bone Marrow; Bone Marrow Cells; Caffeine; Chloramph

1972
[Side effects of drugs. 2. Gastrointestinal side effects].
    Lakartidningen, 1969, Dec-15, Volume: 66

    Topics: Adrenocorticotropic Hormone; Caffeine; Drug-Related Side Effects and Adverse Reactions; Gastrointest

1969
[Drugs and traffic--drug effects on efficiency and its importance for traffic safety. II].
    Zeitschrift fur arztliche Fortbildung, 1968, Nov-15, Volume: 62, Issue:22

    Topics: Accidents, Traffic; Adult; Analgesics; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Caf

1968
[Which drugs can cause glaucoma?].
    Therapie der Gegenwart, 1970, Volume: 109, Issue:4

    Topics: Caffeine; Central Nervous System Stimulants; Drug-Related Side Effects and Adverse Reactions; Epinep

1970
Effect of drugs on carbohydrate metabolism.
    The Proceedings of the Nutrition Society, 1974, Volume: 33, Issue:3

    Topics: Adult; Blood Glucose; Caffeine; Carbohydrate Metabolism; Carbohydrate Metabolism, Inborn Errors; Chi

1974
100-day LD 50 index of chronic toxicity.
    Clinical toxicology, 1971, Volume: 4, Issue:2

    Topics: Acetaminophen; Administration, Oral; Animals; Aspirin; Atropine; Caffeine; DDT; Drug-Related Side Ef

1971
[Iatrogenic damage in pediatrics].
    Minerva medica, 1971, Oct-03, Volume: 62, Issue:74

    Topics: Anti-Bacterial Agents; Bismuth; Caffeine; Child; Child, Preschool; Digitalis Glycosides; Diuretics;

1971
What are our dangerous drugs? 2.
    Journal of hospital dental practice, 1971, Volume: 5, Issue:2

    Topics: Amphetamine; Caffeine; Cocaine; Dentistry; Drug-Related Side Effects and Adverse Reactions; Humans

1971