caffeine has been researched along with Adenocarcinoma in 30 studies
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated p53-dependent and -independent molecular events associated with cell cycle alteration and cell death in human lung adenocarcinoma A549 cells using cryptolepine, a DNA-damaging agent." | 7.73 | Mechanisms of induction of cell cycle arrest and cell death by cryptolepine in human lung adenocarcinoma a549 cells. ( Gooderham, NJ; Zhu, H, 2006) |
| "The present study investigated the inhibitory effects of Polyphenon E [a standardized green tea polyphenol preparation containing 65% (-)-epigallocatechin-3-gallate] and caffeine on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumor progression from adenoma to adenocarcinoma." | 7.73 | Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine. ( Hao, X; Liao, J; Lu, G; Reuhl, KR; Yang, CS; Yang, G, 2006) |
| "Caffeine could enhance the effectiveness of an existing drug for CRC treatment despite having little impact on the cell survival rate of CRC cells." | 5.91 | Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer. ( Kim, KP; Lee, BK; Yoon, S, 2023) |
| " For combined treatment with caffeine and paclitaxel, added caffeine reduced the cytotoxic effect of paclitaxel not only in dose-response but also in time-response curves." | 5.32 | Caffeine diminishes cytotoxic effects of paclitaxel on a human lung adenocarcinoma cell line. ( Akimoto, T; Kitamoto, Y; Mitsuhashi, N; Nakano, T; Sakurai, H, 2003) |
| "In a phase I-II study, 28 patients with advanced pancreatic adenocarcinoma were treated with cisplatin, high-dose cytarabine (ARA-C), and caffeine." | 5.06 | Advanced pancreatic cancer: a phase I-II trial of cisplatin, high-dose cytarabine, and caffeine. ( Botet, J; Dougherty, JB; Kelsen, D; Kemeny, N; Magill, G; Niedzwiecki, D, 1989) |
| "We investigated p53-dependent and -independent molecular events associated with cell cycle alteration and cell death in human lung adenocarcinoma A549 cells using cryptolepine, a DNA-damaging agent." | 3.73 | Mechanisms of induction of cell cycle arrest and cell death by cryptolepine in human lung adenocarcinoma a549 cells. ( Gooderham, NJ; Zhu, H, 2006) |
| "The present study investigated the inhibitory effects of Polyphenon E [a standardized green tea polyphenol preparation containing 65% (-)-epigallocatechin-3-gallate] and caffeine on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumor progression from adenoma to adenocarcinoma." | 3.73 | Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine. ( Hao, X; Liao, J; Lu, G; Reuhl, KR; Yang, CS; Yang, G, 2006) |
| " In this study, we examined the effect of CYP1A2 activity using a urinary caffeine metabolic ratio assay for 54 Chinese women with newly diagnosed lung cancer (including 28 adenocarcinomas) and 174 hospital controls." | 3.71 | Cytochrome P4501A2 (CYP1A2) activity and lung cancer risk: a preliminary study among Chinese women in Singapore. ( Eng, P; Lee, EJ; Lee, HP; Poh, WT; Seow, A; Tan, WC; Teh, M; Wang, YT; Zhao, B, 2001) |
| "We have examined the modulation of radiosensitivity by using caffeine in two human sarcoma cell lines both with a p53 mutation (US8-93 and LMS6-93)." | 3.71 | Loss of G2/M arrest correlates with radiosensitization in two human sarcoma cell lines with mutant p53. ( Bache, M; Bartel, F; Dunst, J; Meye, A; Pigorsch, S; Rath, FW; Schmidt, H; Taubert, H; Würl, P, 2001) |
| "A study of MCF-7 human breast cancer cells was undertaken to ascertain the degree of apoptosis induction by paclitaxel and if the induction of apoptosis could be enhanced by caffeine." | 3.69 | Paclitaxel-induced apoptosis in MCF-7 breast-cancer cells. ( Christensen, C; Deppe, G; Lawrence, WD; Ruan, H; Saunders, DE; Wappler, NL, 1997) |
| "In locally advanced pancreatic cancer, the utilization of chemotherapy and radiotherapy is increasing, although in view of the reported long-term results of several contemporary trials, further improvements are certainly needed." | 2.71 | Chemoradiotherapy in the treatment of regional pancreatic carcinoma: a phase II study. ( Adsay, V; Al-Sukhun, S; Ben-Josef, E; Forman, JD; Heilbrun, LK; Levin, K; Philip, PA; Shields, AF; Soulen, R; Vaitkevicius, VK; Weaver, D; Zalupski, MM, 2003) |
| "Caffeine could enhance the effectiveness of an existing drug for CRC treatment despite having little impact on the cell survival rate of CRC cells." | 1.91 | Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer. ( Kim, KP; Lee, BK; Yoon, S, 2023) |
| "We therefore used LNCaP human prostate cancer cells as a model to identify stimuli that lead to AIbZIP activation and define the transcriptional targets of AIbZIP." | 1.34 | Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells. ( Ben Aicha, S; Calvo, E; Fournier, A; Labrie, C; Lessard, J; Pelletier, M, 2007) |
| " For combined treatment with caffeine and paclitaxel, added caffeine reduced the cytotoxic effect of paclitaxel not only in dose-response but also in time-response curves." | 1.32 | Caffeine diminishes cytotoxic effects of paclitaxel on a human lung adenocarcinoma cell line. ( Akimoto, T; Kitamoto, Y; Mitsuhashi, N; Nakano, T; Sakurai, H, 2003) |
| "Hyperoxia has been shown to cause DNA damage resulting in growth arrest of cells in p53-dependent, as well as p53-independent, pathways." | 1.32 | Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites. ( Das, KC; Dashnamoorthy, R, 2004) |
| "Caffeine is a model radiosensitizing agent that is thought to work by abrogating the radiation-induced G(2)-phase checkpoint." | 1.31 | Caffeine induces TP53-independent G(1)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner. ( Martinez, JD; Qi, W; Qiao, D, 2002) |
| "Pancreatic cancer is the fifth leading cause of cancer related deaths in the United States." | 1.30 | Molecular effects of taxol and caffeine on pancreatic cancer cells. ( Al-Katib, AA; Aranha, O; Gururajanna, B; Li, YW; Sarkar, FH; Vaitkevicius, VK, 1999) |
| "Both caffeine and NaCl treatments exerted growth retardation effects, the suppression being stronger with caffeine than NaCl, and animals in group 1 (NaCl plus caffeine) showing the lowest body weight." | 1.29 | Effects of caffeine on glandular stomach carcinogenesis induced in rats by N-methyl-N'-nitro-N-nitrosoguanidine and sodium chloride. ( Furukawa, F; Hasegawa, T; Ikezaki, S; Imazawa, T; Nishikawa, A; Takahashi, M, 1995) |
| "The tumor lines were hepatocellular carcinoma and colon adenocarcinoma." | 1.29 | Differential radiosensitization of radioresistant human cancer cells by caffeine. ( Boonkitticharoen, V; Laohathai, K; Puribhat, S, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.00) | 18.7374 |
| 1990's | 9 (30.00) | 18.2507 |
| 2000's | 12 (40.00) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, S | 1 |
| Li, Z | 1 |
| Bai, X | 1 |
| Feng, J | 1 |
| Su, R | 1 |
| Song, L | 1 |
| Yang, H | 1 |
| Zhan, X | 1 |
| Xia, X | 1 |
| Lü, X | 1 |
| Shi, C | 1 |
| Yoon, S | 1 |
| Lee, BK | 1 |
| Kim, KP | 1 |
| Arab, L | 1 |
| Su, LJ | 1 |
| Steck, SE | 1 |
| Ang, A | 1 |
| Fontham, ET | 1 |
| Bensen, JT | 1 |
| Mohler, JL | 1 |
| Kitamoto, Y | 1 |
| Sakurai, H | 1 |
| Mitsuhashi, N | 1 |
| Akimoto, T | 1 |
| Nakano, T | 1 |
| Das, KC | 1 |
| Dashnamoorthy, R | 1 |
| Al-Sukhun, S | 1 |
| Zalupski, MM | 2 |
| Ben-Josef, E | 1 |
| Vaitkevicius, VK | 3 |
| Philip, PA | 1 |
| Soulen, R | 1 |
| Weaver, D | 1 |
| Adsay, V | 1 |
| Heilbrun, LK | 1 |
| Levin, K | 1 |
| Forman, JD | 1 |
| Shields, AF | 2 |
| Al-Wadei, HA | 1 |
| Takahashi, T | 1 |
| Schuller, HM | 1 |
| Zhu, H | 1 |
| Gooderham, NJ | 1 |
| Lu, G | 1 |
| Liao, J | 1 |
| Yang, G | 1 |
| Reuhl, KR | 1 |
| Hao, X | 1 |
| Yang, CS | 1 |
| Ben Aicha, S | 1 |
| Lessard, J | 1 |
| Pelletier, M | 1 |
| Fournier, A | 1 |
| Calvo, E | 1 |
| Labrie, C | 1 |
| Murnane, JP | 1 |
| Byfield, JE | 1 |
| Chen, CT | 1 |
| Wang, CH | 1 |
| Johansson, SL | 1 |
| Russell, KJ | 1 |
| Wiens, LW | 1 |
| Demers, GW | 1 |
| Galloway, DA | 1 |
| Plon, SE | 1 |
| Groudine, M | 1 |
| Nishikawa, A | 1 |
| Furukawa, F | 1 |
| Imazawa, T | 1 |
| Ikezaki, S | 1 |
| Hasegawa, T | 1 |
| Takahashi, M | 1 |
| Boonkitticharoen, V | 1 |
| Laohathai, K | 1 |
| Puribhat, S | 1 |
| Clunes, MT | 1 |
| Kemp, PJ | 1 |
| Saunders, DE | 1 |
| Lawrence, WD | 1 |
| Christensen, C | 1 |
| Wappler, NL | 1 |
| Ruan, H | 1 |
| Deppe, G | 1 |
| Hagiwara, A | 1 |
| Boonyaphiphat, P | 1 |
| Tanaka, H | 1 |
| Kawabe, M | 1 |
| Tamano, S | 1 |
| Kaneko, H | 1 |
| Matsui, M | 1 |
| Hirose, M | 1 |
| Ito, N | 1 |
| Shirai, T | 1 |
| Gururajanna, B | 1 |
| Al-Katib, AA | 1 |
| Li, YW | 1 |
| Aranha, O | 1 |
| Sarkar, FH | 1 |
| Tunca, B | 1 |
| Egeli, U | 1 |
| Zorluoglu, A | 1 |
| Yilmazlar, T | 1 |
| Yerci, O | 1 |
| Kizil, A | 1 |
| Ahmed, S | 1 |
| Du, W | 1 |
| Arlauskas, P | 1 |
| Gordon, C | 1 |
| Kellogg, C | 1 |
| Seow, A | 1 |
| Zhao, B | 1 |
| Lee, EJ | 1 |
| Poh, WT | 1 |
| Teh, M | 1 |
| Eng, P | 1 |
| Wang, YT | 1 |
| Tan, WC | 1 |
| Lee, HP | 1 |
| Bache, M | 1 |
| Pigorsch, S | 1 |
| Dunst, J | 1 |
| Würl, P | 1 |
| Meye, A | 1 |
| Bartel, F | 1 |
| Schmidt, H | 1 |
| Rath, FW | 1 |
| Taubert, H | 1 |
| Qi, W | 1 |
| Qiao, D | 1 |
| Martinez, JD | 1 |
| Kelsen, D | 2 |
| Hudis, C | 1 |
| Niedzwiecki, D | 2 |
| Dougherty, J | 1 |
| Casper, E | 1 |
| Botet, J | 2 |
| Vinciguerra, V | 1 |
| Rosenbluth, R | 1 |
| Ohsaki, Y | 1 |
| Ishida, S | 1 |
| Fujikane, T | 1 |
| Akiba, Y | 1 |
| Osanai, S | 1 |
| Onodera, S | 1 |
| Dougherty, JB | 1 |
| Kemeny, N | 1 |
| Magill, G | 1 |
| Coffey, RJ | 1 |
| Go, VL | 1 |
| Zinsmeister, AR | 1 |
| DiMagno, EP | 1 |
| Kyriazis, AP | 1 |
| Kyriazis, AA | 1 |
| Yagoda, A | 1 |
| Liu, T | 1 |
| Smith, GW | 1 |
| Rankin, JT | 1 |
4 trials available for caffeine and Adenocarcinoma
| Article | Year |
|---|---|
Chemoradiotherapy in the treatment of regional pancreatic carcinoma: a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Caff | 2003 |
Cisplatin, cytarabine, caffeine, and continuously infused 5-fluorouracil (PACE) in the treatment of advanced pancreatic carcinoma: a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 2000 |
A phase III comparison trial of streptozotocin, mitomycin, and 5-fluorouracil with cisplatin, cytosine arabinoside, and caffeine in patients with advanced pancreatic carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Carboplatin; | 1991 |
Advanced pancreatic cancer: a phase I-II trial of cisplatin, high-dose cytarabine, and caffeine.
Topics: Acute Disease; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; | 1989 |
26 other studies available for caffeine and Adenocarcinoma
| Article | Year |
|---|---|
The biochemical characteristics of viable but nonculturable state Yersinia enterocolitica induced by lactic acid stress and its presence in food systems.
Topics: Adenocarcinoma; Caco-2 Cells; Caffeine; Humans; Lactic Acid; Yersinia enterocolitica | 2023 |
Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer.
Topics: Adenocarcinoma; Caffeine; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; D | 2023 |
Coffee consumption and prostate cancer aggressiveness among African and Caucasian Americans in a population-based study.
Topics: Adenocarcinoma; Adult; Aged; Black or African American; Caffeine; Coffee; Diet; Humans; Louisiana; M | 2012 |
Caffeine diminishes cytotoxic effects of paclitaxel on a human lung adenocarcinoma cell line.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Caffeine; Depression, Chemical; Dose-Response Rel | 2003 |
Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites.
Topics: Adenocarcinoma; Androstadienes; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle Protein | 2004 |
Caffeine stimulates the proliferation of human lung adenocarcinoma cells and small airway epithelial cells via activation of PKA, CREB and ERK1/2.
Topics: Adenocarcinoma; Blotting, Western; Caffeine; Cell Line, Tumor; Central Nervous System Stimulants; CR | 2006 |
Mechanisms of induction of cell cycle arrest and cell death by cryptolepine in human lung adenocarcinoma a549 cells.
Topics: Adenocarcinoma; Alkaloids; Androstadienes; Apoptosis; Caffeine; Cell Cycle; Cell Line, Tumor; Chromo | 2006 |
Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Caffeine; Catechin; Cell Proliferation; Dise | 2006 |
Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells.
Topics: Adenocarcinoma; Amino Acid Sequence; Basic-Leucine Zipper Transcription Factors; Brefeldin A; Caffei | 2007 |
The structure of methylated xanthines in relation to their effects on DNA synthesis and cell lethality in nitrogen mustard-treated cells.
Topics: Adenocarcinoma; Caffeine; Cell Line; Cell Survival; DNA Replication; Humans; Mechlorethamine; Struct | 1981 |
Carcinogenicity of analgesics: long-term treatment of Sprague-Dawley rats with phenacetin, phenazone, caffeine and paracetamol (acetamidophen).
Topics: Acetaminophen; Adenocarcinoma; Analgesics; Animals; Antipyrine; Caffeine; Carcinogens; Carcinoma, Sq | 1981 |
Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint-competent cells.
Topics: Adenocarcinoma; Caffeine; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Radia | 1995 |
Effects of caffeine on glandular stomach carcinogenesis induced in rats by N-methyl-N'-nitro-N-nitrosoguanidine and sodium chloride.
Topics: Adenocarcinoma; Animals; Biological Assay; Body Weight; Caffeine; Cell Division; Drug Interactions; | 1995 |
Differential radiosensitization of radioresistant human cancer cells by caffeine.
Topics: Adenocarcinoma; Caffeine; Carcinoma, Hepatocellular; Colonic Neoplasms; Gamma Rays; Humans; Radiatio | 1993 |
P2u purinoceptor modulation of intracellular Ca2+ in a human lung adenocarcinoma cell line: down-regulation of Ca2+ influx by protein kinase C.
Topics: Adenocarcinoma; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Benzoquinone | 1996 |
Paclitaxel-induced apoptosis in MCF-7 breast-cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasm | 1997 |
Organ-dependent modifying effects of caffeine, and two naturally occurring antioxidants alpha-tocopherol and n-tritriacontane-16,18-dione, on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary and colonic carcinogenesis in female F344
Topics: Adenocarcinoma; Adenoma; Animals; Antioxidants; Caffeine; Carcinogens; Chemoprevention; Colonic Neop | 1999 |
Molecular effects of taxol and caffeine on pancreatic cancer cells.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Caffei | 1999 |
The expression frequency of common fragile sites and genetic predisposition to colon cancer.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Alu Elements; Aphidicolin; Bromodeoxyuridine; Caffeine; Chi | 2000 |
Cytochrome P4501A2 (CYP1A2) activity and lung cancer risk: a preliminary study among Chinese women in Singapore.
Topics: Adenocarcinoma; Age Factors; Aged; Arylamine N-Acetyltransferase; Caffeine; Case-Control Studies; Ch | 2001 |
Loss of G2/M arrest correlates with radiosensitization in two human sarcoma cell lines with mutant p53.
Topics: Adenocarcinoma; Alleles; Apoptosis; Blotting, Western; Caffeine; Cell Survival; Combined Modality Th | 2001 |
Caffeine induces TP53-independent G(1)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner.
Topics: Adenocarcinoma; Apoptosis; Caffeine; CDC2 Protein Kinase; CDC2-CDC28 Kinases; cdc25 Phosphatases; Ce | 2002 |
[Combination effect of caffeine and cisplatin on a cisplatin resistant human lung cancer cell line].
Topics: Adenocarcinoma; Caffeine; Cell Cycle; Cisplatin; Drug Resistance; Drug Synergism; Humans; Lung Neopl | 1990 |
The acute effects of coffee and caffeine on human interdigestive exocrine pancreatic secretion.
Topics: Adenocarcinoma; Adult; Caffeine; Coffee; Fasting; Female; Gastric Acid; Gastrins; Humans; Male; Midd | 1986 |
Enhanced therapeutic effect of cis-diamminedichloroplatinum(II) against nude mouse grown human pancreatic adenocarcinoma when combined with 1-beta-D-arabinofuranosylcytosine and caffeine.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Cytara | 1985 |
Renal pelvic tumour associated with analgesic abuse.
Topics: Adenocarcinoma; Aged; Alcoholism; Analgesics; Aspirin; Caffeine; Codeine; Drug Synergism; Female; Hu | 1972 |