caffeine has been researched along with Active Hyperemia in 21 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aims of this review are to examine the biochemical features of theophylline, caffeine, adenosine, and dipyridamole, their effects on coronary hyperemia, and to make recommendations on performing hyperemic lesion assessment after taking caffeine or theophylline." | 8.85 | Effects of caffeine and theophylline on coronary hyperemia induced by adenosine or dipyridamole. ( Kern, MJ; Salcedo, J, 2009) |
| " The purpose of this study was to determine the effects of coffee intake <4 h prior to stress perfusion cardiac magnetic resonance imaging (CMR) in regadenoson- versus adenosine-induced hyperemia as measured with T1-mapping." | 7.85 | Effects of caffeine intake prior to stress cardiac magnetic resonance perfusion imaging on regadenoson- versus adenosine-induced hyperemia as measured by T1 mapping. ( Kaandorp, TAM; Kuijpers, D; Oudkerk, M; van der Harst, P; van Dijk, R; van Dijkman, PRM; Vliegenthart, R, 2017) |
| "We examined whether caffeine attenuated intravenous adenosine-induced hyperemia in the measurement of fractional flow reserve (FFR) and whether an increased dose of adenosine overcame the caffeine antagonism." | 7.80 | Effect of caffeine on intravenous adenosine-induced hyperemia in fractional flow reserve measurement. ( Matsuda, T; Matsumoto, H; Mikuri, M; Nakatsuma, K; Shimada, T; Ushimaru, S; Yamazaki, T, 2014) |
| "It is believed that adenosine is released in ischemic tissues and contributes to reactive hyperemia." | 7.70 | Intravascular source of adenosine during forearm ischemia in humans: implications for reactive hyperemia. ( Angel, M; Biaggioni, I; Cavalcante, J; Christman, B; Costa, F; Haile, V; Sulur, P, 1999) |
| " Hyperemia was induced by continuous intravenous ATP infusion at 150 μg/kg/min (IVATP150) and 210 μg/kg/min (IVATP210), and by intracoronary administration of nicorandil 2 mg (ICNIC2mg) as a reference standard." | 5.34 | Influence of caffeine intake on intravenous adenosine-induced fractional flow reserve. ( Fujii, K; Hirofumi, K; Hiroto, T; Kasumi, I; Katsuyuki, H; Mikio, K; Rui, I; Satoru, O; Shin, T; Shingo, Y; Sho, N; Wataru, Y; Yorihiko, H; Yuji, S; Yusuke, T, 2020) |
| "The aims of this review are to examine the biochemical features of theophylline, caffeine, adenosine, and dipyridamole, their effects on coronary hyperemia, and to make recommendations on performing hyperemic lesion assessment after taking caffeine or theophylline." | 4.85 | Effects of caffeine and theophylline on coronary hyperemia induced by adenosine or dipyridamole. ( Kern, MJ; Salcedo, J, 2009) |
| "Semiquantitative perfusion analysis was performed in 25 patients who underwent: 1) caffeine-naïve adenosine stress CMR demonstrating myocardial ischemia and, 2) repeat adenosine stress CMR after intake of caffeine." | 3.91 | Impact of caffeine on myocardial perfusion reserve assessed by semiquantitative adenosine stress perfusion cardiovascular magnetic resonance. ( Bekeredjian, R; Chatzitofi, M; Greulich, S; Kaesemann, P; Löbig, S; Mahrholdt, H; Sechtem, U; Seitz, A; Tauscher, G, 2019) |
| " The purpose of this study was to determine the effects of coffee intake <4 h prior to stress perfusion cardiac magnetic resonance imaging (CMR) in regadenoson- versus adenosine-induced hyperemia as measured with T1-mapping." | 3.85 | Effects of caffeine intake prior to stress cardiac magnetic resonance perfusion imaging on regadenoson- versus adenosine-induced hyperemia as measured by T1 mapping. ( Kaandorp, TAM; Kuijpers, D; Oudkerk, M; van der Harst, P; van Dijk, R; van Dijkman, PRM; Vliegenthart, R, 2017) |
| "We examined whether caffeine attenuated intravenous adenosine-induced hyperemia in the measurement of fractional flow reserve (FFR) and whether an increased dose of adenosine overcame the caffeine antagonism." | 3.80 | Effect of caffeine on intravenous adenosine-induced hyperemia in fractional flow reserve measurement. ( Matsuda, T; Matsumoto, H; Mikuri, M; Nakatsuma, K; Shimada, T; Ushimaru, S; Yamazaki, T, 2014) |
| "Myocardial perfusion scintigraphy (MPS) was used to assess adenosine-induced hyperemia in 30 patients before (baseline) and after coffee ingestion (caffeine)." | 3.74 | High-dose adenosine overcomes the attenuation of myocardial perfusion reserve caused by caffeine. ( Anagnostopoulos, C; Donovan, J; Harbinson, M; Loong, CY; Reyes, E; Underwood, SR, 2008) |
| " Myocardial blood flow at rest and during adenosine-induced hyperemia 2 hours after consumption of decaffeinated coffee and again without caffeine intake were quantified by ammonia PET." | 3.73 | [Effect of caffeine on myocardial blood flow during pharmacological vasodilation]. ( Burchert, W; Fricke, E; Horstkotte, D; Wielepp, JP, 2005) |
| "This study demonstrates that ATP has the potential to induce greater hyperemia than dipyridamole, whereas hyperemic responses to ATP and dipyridamole are similarly attenuated after caffeine intake." | 3.72 | Effect of caffeine intake on myocardial hyperemic flow induced by adenosine triphosphate and dipyridamole. ( Kitano, H; Konishi, J; Kubo, S; Magata, Y; Mamede, M; Mukai, T; Tadamura, E; Tamaki, N; Toyoda, H; Yamamuro, M, 2004) |
| "It is believed that adenosine is released in ischemic tissues and contributes to reactive hyperemia." | 3.70 | Intravascular source of adenosine during forearm ischemia in humans: implications for reactive hyperemia. ( Angel, M; Biaggioni, I; Cavalcante, J; Christman, B; Costa, F; Haile, V; Sulur, P, 1999) |
| "In a dosage of 50 mg bid, eplerenone does not augment extracellular adenosine formation in healthy human subjects." | 2.79 | The effect of eplerenone on adenosine formation in humans in vivo: a double-blinded randomised controlled study. ( Bilos, A; Deinum, J; Donders, AR; Riksen, NP; Rongen, GA; van den Berg, TN, 2014) |
| "Caffeine was ingested at <12 hours in 85 patients, at 12-24 hours in 35 patients, and at >24 hours in 89 patients." | 1.62 | Linear concentration-response relationship of serum caffeine with adenosine-induced fractional flow reserve overestimation: a comparison with papaverine. ( Hosonuma, M; Inoue, K; Kondo, S; Masaki, R; Matsumoto, H; Ogura, K; Oishi, Y; Okada, N; Sakai, K; Sato, S; Sekimoto, T; Shinke, T; Sumida, A; Takahashi, H; Tanaka, H; Tsujita, H; Tsukamoto, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, H | 1 |
| Matsumoto, H | 3 |
| Takahashi, H | 2 |
| Hosonuma, M | 1 |
| Sato, S | 1 |
| Ogura, K | 1 |
| Oishi, Y | 1 |
| Masaki, R | 1 |
| Sakai, K | 1 |
| Sekimoto, T | 1 |
| Kondo, S | 1 |
| Tsujita, H | 1 |
| Tsukamoto, S | 1 |
| Sumida, A | 1 |
| Okada, N | 1 |
| Inoue, K | 1 |
| Shinke, T | 1 |
| Kasumi, I | 1 |
| Fujii, K | 1 |
| Satoru, O | 1 |
| Shin, T | 1 |
| Katsuyuki, H | 1 |
| Hiroto, T | 1 |
| Rui, I | 1 |
| Shingo, Y | 1 |
| Sho, N | 1 |
| Wataru, Y | 1 |
| Hirofumi, K | 1 |
| Yusuke, T | 1 |
| Mikio, K | 1 |
| Yuji, S | 1 |
| Yorihiko, H | 1 |
| van Dijk, R | 2 |
| Kuijpers, D | 2 |
| Kaandorp, TAM | 1 |
| van Dijkman, PRM | 1 |
| Vliegenthart, R | 1 |
| van der Harst, P | 2 |
| Oudkerk, M | 2 |
| Ties, D | 1 |
| Melik, Z | 1 |
| Princi, T | 1 |
| Grill, V | 1 |
| Cankar, K | 1 |
| Seitz, A | 1 |
| Kaesemann, P | 1 |
| Chatzitofi, M | 1 |
| Löbig, S | 1 |
| Tauscher, G | 1 |
| Bekeredjian, R | 1 |
| Sechtem, U | 1 |
| Mahrholdt, H | 1 |
| Greulich, S | 1 |
| van den Berg, TN | 1 |
| Deinum, J | 1 |
| Bilos, A | 1 |
| Donders, AR | 1 |
| Rongen, GA | 2 |
| Riksen, NP | 2 |
| Nakatsuma, K | 1 |
| Shimada, T | 2 |
| Ushimaru, S | 2 |
| Mikuri, M | 2 |
| Yamazaki, T | 2 |
| Matsuda, T | 2 |
| Takahashi, N | 1 |
| Kawada, T | 1 |
| Reyes, E | 1 |
| Loong, CY | 1 |
| Harbinson, M | 1 |
| Donovan, J | 1 |
| Anagnostopoulos, C | 1 |
| Underwood, SR | 1 |
| Namdar, M | 1 |
| Schepis, T | 1 |
| Koepfli, P | 1 |
| Gaemperli, O | 1 |
| Siegrist, PT | 1 |
| Grathwohl, R | 1 |
| Valenta, I | 1 |
| Delaloye, R | 1 |
| Klainguti, M | 1 |
| Wyss, CA | 1 |
| Lüscher, TF | 1 |
| Kaufmann, PA | 1 |
| Salcedo, J | 1 |
| Kern, MJ | 1 |
| Harris, RA | 1 |
| Nishiyama, SK | 1 |
| Wray, DW | 1 |
| Richardson, RS | 1 |
| Belzowzki, A | 1 |
| Bergren, D | 1 |
| Brugler, A | 1 |
| Hillman, BG | 1 |
| Hillman, KC | 1 |
| Hillman, SR | 1 |
| Kuss, B | 1 |
| Ngo, BT | 1 |
| Pisarri, T | 1 |
| Rendell, MS | 1 |
| Thompson, SL | 1 |
| Turner, SA | 1 |
| Aqel, RA | 1 |
| Zoghbi, GJ | 1 |
| Trimm, JR | 1 |
| Baldwin, SA | 1 |
| Iskandrian, AE | 1 |
| Kubo, S | 1 |
| Tadamura, E | 1 |
| Toyoda, H | 1 |
| Mamede, M | 1 |
| Yamamuro, M | 1 |
| Magata, Y | 1 |
| Mukai, T | 1 |
| Kitano, H | 1 |
| Tamaki, N | 1 |
| Konishi, J | 1 |
| Wielepp, JP | 1 |
| Fricke, E | 1 |
| Horstkotte, D | 1 |
| Burchert, W | 1 |
| Meijer, P | 1 |
| Wouters, CW | 1 |
| van den Broek, PH | 1 |
| Scheffer, GJ | 1 |
| Smits, P | 1 |
| McGeoch, RJ | 1 |
| Oldroyd, KG | 1 |
| Costa, F | 1 |
| Sulur, P | 1 |
| Angel, M | 1 |
| Cavalcante, J | 1 |
| Haile, V | 1 |
| Christman, B | 1 |
| Biaggioni, I | 1 |
| Stüttgen, G | 1 |
| Neumann, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Caffeine on Myocardial Oxygenation[NCT04585854] | 29 participants (Actual) | Interventional | 2020-11-13 | Completed | |||
| Effects of the Selective Mineralocorticoid Receptor Antagonist Eplerenone on Extracellular Adenosine Formation in Humans in Vivo[NCT01837108] | Phase 4 | 14 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Effect of Low Intensity Strength Training Combined With Moderate Blood Flow Restriction on Muscle Vasodilatation and Arterial Stiffness in Elders With Low Gait Velocity.[NCT03272737] | 26 participants (Actual) | Interventional | 2018-02-04 | Completed | |||
| Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals[NCT05423470] | 41 participants (Actual) | Interventional | 2019-05-30 | Completed | |||
| Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer[NCT02549534] | 29 participants (Actual) | Observational | 2015-09-30 | Completed | |||
| Is Augmentation of PORH by Rosuvastatin Adenosine-receptor Mediated?[NCT00851175] | Phase 4 | 8 participants (Anticipated) | Interventional | 2009-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for caffeine and Active Hyperemia
| Article | Year |
|---|---|
Effects of Caffeine on Myocardial Blood Flow: A Systematic Review.
Topics: Adult; Aged; Caffeine; Clinical Decision-Making; Coronary Artery Disease; Coronary Circulation; Fema | 2018 |
Effects of caffeine and theophylline on coronary hyperemia induced by adenosine or dipyridamole.
Topics: Adenosine; Animals; Caffeine; Coronary Circulation; Coronary Disease; Dipyridamole; Drug Administrat | 2009 |
Pharmacological options for inducing maximal hyperaemia during studies of coronary physiology.
Topics: Adenosine; Adenosine Triphosphate; Animals; Caffeine; Coronary Stenosis; Dobutamine; Fractional Flow | 2008 |
6 trials available for caffeine and Active Hyperemia
| Article | Year |
|---|---|
Influence of caffeine intake on intravenous adenosine-induced fractional flow reserve.
Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Caffeine; Female; Fractional Flow Reserve, Myocardi | 2020 |
The effect of caffeine on cutaneous postocclusive reactive hyperaemia.
Topics: Adult; Blood Pressure; Caffeine; Female; Heart Rate; Humans; Hyperemia; Male; Skin | 2019 |
The effect of eplerenone on adenosine formation in humans in vivo: a double-blinded randomised controlled study.
Topics: Adenosine; Caffeine; Dipyridamole; Double-Blind Method; Eplerenone; Forearm; Hemodynamics; Humans; H | 2014 |
Caffeine impairs myocardial blood flow response to physical exercise in patients with coronary artery disease as well as in age-matched controls.
Topics: Aging; Caffeine; Case-Control Studies; Coronary Artery Disease; Coronary Circulation; Exercise; Fema | 2009 |
Effect of caffeine administered intravenously on intracoronary-administered adenosine-induced coronary hemodynamics in patients with coronary artery disease.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adult; Caffeine; Coronary Artery Disease; Hemodynamics | 2004 |
Dipyridamole enhances ischaemia-induced reactive hyperaemia by increased adenosine receptor stimulation.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Forearm; Humans; Hyperemia | 2008 |
12 other studies available for caffeine and Active Hyperemia
| Article | Year |
|---|---|
Linear concentration-response relationship of serum caffeine with adenosine-induced fractional flow reserve overestimation: a comparison with papaverine.
Topics: Adenosine; Caffeine; Coronary Angiography; Coronary Stenosis; Fractional Flow Reserve, Myocardial; H | 2021 |
Effects of caffeine intake prior to stress cardiac magnetic resonance perfusion imaging on regadenoson- versus adenosine-induced hyperemia as measured by T1 mapping.
Topics: Adenosine; Aged; Caffeine; Coffee; Coronary Artery Disease; Coronary Circulation; Female; Humans; Hy | 2017 |
Impact of caffeine on myocardial perfusion reserve assessed by semiquantitative adenosine stress perfusion cardiovascular magnetic resonance.
Topics: Adenosine; Aged; Caffeine; Coronary Circulation; Female; Humans; Hyperemia; Magnetic Resonance Imagi | 2019 |
Effect of caffeine on intravenous adenosine-induced hyperemia in fractional flow reserve measurement.
Topics: Adenosine; Administration, Oral; Aged; Blood Pressure; Caffeine; Coronary Angiography; Coronary Sten | 2014 |
Is Caffeine Abstention Necessary Before Adenosine-Induced Fractional Flow Reserve Measurement?
Topics: Adenosine; Caffeine; Fractional Flow Reserve, Myocardial; Humans; Hyperemia; Papaverine; Prospective | 2015 |
High-dose adenosine overcomes the attenuation of myocardial perfusion reserve caused by caffeine.
Topics: Adenosine; Aged; Caffeine; Central Nervous System Stimulants; Coffee; Coronary Artery Disease; Coron | 2008 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
Ultrasound assessment of flow-mediated dilation.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Caffeine; Cardiovascular Diseases; Endothelium, Va | 2010 |
The effect of vasoactive agents on post-pressure hyperemia.
Topics: Adenosine; Alprostadil; Animals; Area Under Curve; Arterial Pressure; Buffers; Caffeine; Dinoproston | 2012 |
Effect of caffeine intake on myocardial hyperemic flow induced by adenosine triphosphate and dipyridamole.
Topics: Adenosine Triphosphate; Adult; Caffeine; Coronary Circulation; Dipyridamole; Heart; Hemodynamics; Hu | 2004 |
[Effect of caffeine on myocardial blood flow during pharmacological vasodilation].
Topics: Adenosine; Caffeine; Coronary Circulation; Coronary Disease; Coronary Vessels; Drug Interactions; Hu | 2005 |
Intravascular source of adenosine during forearm ischemia in humans: implications for reactive hyperemia.
Topics: Adenosine; Adult; Caffeine; Female; Forearm; Humans; Hyperemia; Ischemia; Male; Microdialysis; Muscl | 1999 |
[Inhibition of dermographism in human skin after topical application of caffeine].
Topics: Acetylcholine; Caffeine; Erythema; Humans; Hyperemia; Injections, Subcutaneous; Skin; Skin Manifesta | 1972 |