Page last updated: 2024-10-24

caffeine and Acquired Immunodeficiency Syndrome

caffeine has been researched along with Acquired Immunodeficiency Syndrome in 7 studies

Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

Research Excerpts

ExcerptRelevanceReference
"A spectrum of adverse drug reactions that are caused by the combined action of drugs and viruses has been described: ampicillin rash in acute infectious mononucleosis; Reye's syndrome; hypersensitivity reactions to sulphonamides in patients with HIV infection; drug-induced agranulocytosis; paracetamol (acetaminophen) hepatotoxicity; aspirin (acetylsalicyclic acid)-induced asthma; Epstein-Barr virus-associated lymphoma and methotrexate; and AIDS-related Kaposi's sarcoma and nitrite use."4.79Role of viral infections in the induction of adverse drug reactions. ( Levy, M, 1997)
"To investigate the relationship between high incidence of adverse dapsone reactions in acquired immunodeficiency syndrome (AIDS) patients and slow acetylate phenotype or low plasma/lymphocyte glutathione level of these patients."3.69Relationship between high incidence of adverse dapsone reactions and slow acetylate phenotype or low plasma/lymphocyte glutathione level. ( Guo, R; Lauterberg, B; Thormann, W, 1996)
"In a cross-sectional study, 105 HIV-positive patients and patients with acquired immunodeficiency syndrome (AIDS) were phenotyped for NAT2 activity with use of caffeine as an in vivo probe; 50 of these patients were also genotyped by restriction mapping and allele-specific amplification."3.69N-acetylation among HIV-positive patients and patients with AIDS: when is fast, fast and slow, slow? ( DiGirolamo, A; Gilfix, BM; O'Neil, WM; Tsoukas, CM; Wainer, IW, 1997)
"Caffeine was used to assess acetylation status and indexes of oxidative drug metabolism (demethylation, xanthine oxidation, and 8-hydroxylation) in a control group and in three groups of patients infected with human immunodeficiency virus (HIV): patients with acquired immunodeficiency syndrome (AIDS) who had acute illnesses, stable patients with AIDS, and asymptomatic patients infected with HIV."3.68Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome. ( Benowitz, NL; Lee, BL; Sullam, PM; Wong, D, 1993)
"Isoniazid was administered at 300 mg once daily for 5 days to 80 adult volunteers."2.70Effects of gender, AIDS, and acetylator status on intrapulmonary concentrations of isoniazid. ( Conte, JE; Duncan, S; Golden, JA; Kipps, J; McKenna, E; McQuitty, M; Zurlinden, E, 2002)
"One hundred and thirty-six AIDS patients were studied."1.31Prospective evaluation of detoxification pathways as markers of cutaneous adverse reactions to sulphonamides in AIDS. ( Aractingi, S; Beaune, P; Cabelguenne, A; Chosidow, O; Loriot, MA; Wolkenstein, P, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Conte, JE1
Golden, JA1
McQuitty, M1
Kipps, J1
Duncan, S1
McKenna, E1
Zurlinden, E1
Lee, BL1
Wong, D1
Benowitz, NL1
Sullam, PM1
Levy, M1
Guo, R1
Thormann, W1
Lauterberg, B1
O'Neil, WM1
Gilfix, BM1
DiGirolamo, A1
Tsoukas, CM1
Wainer, IW1
Wolkenstein, P1
Loriot, MA1
Aractingi, S1
Cabelguenne, A1
Beaune, P1
Chosidow, O1
Weinberg, CR1

Reviews

1 review available for caffeine and Acquired Immunodeficiency Syndrome

ArticleYear
Role of viral infections in the induction of adverse drug reactions.
    Drug safety, 1997, Volume: 16, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Agranulocytosis; Ampicillin; Caffeine; Drug-Related Side Effects

1997

Trials

1 trial available for caffeine and Acquired Immunodeficiency Syndrome

ArticleYear
Effects of gender, AIDS, and acetylator status on intrapulmonary concentrations of isoniazid.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:8

    Topics: Acetylation; Acquired Immunodeficiency Syndrome; Adult; Antitubercular Agents; Body Fluids; Bronchoa

2002

Other Studies

5 other studies available for caffeine and Acquired Immunodeficiency Syndrome

ArticleYear
Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome.
    Clinical pharmacology and therapeutics, 1993, Volume: 53, Issue:5

    Topics: Acetylation; Acquired Immunodeficiency Syndrome; Adult; Analysis of Variance; Caffeine; Coffee; Fema

1993
Relationship between high incidence of adverse dapsone reactions and slow acetylate phenotype or low plasma/lymphocyte glutathione level.
    Chinese medical journal, 1996, Volume: 109, Issue:12

    Topics: Acetylation; Acquired Immunodeficiency Syndrome; Adult; Anti-Infective Agents; Caffeine; Chromatogra

1996
N-acetylation among HIV-positive patients and patients with AIDS: when is fast, fast and slow, slow?
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:3

    Topics: Acetylation; Acquired Immunodeficiency Syndrome; Alleles; Arylamine N-Acetyltransferase; Caffeine; C

1997
Prospective evaluation of detoxification pathways as markers of cutaneous adverse reactions to sulphonamides in AIDS.
    Pharmacogenetics, 2000, Volume: 10, Issue:9

    Topics: Acetylation; Acquired Immunodeficiency Syndrome; Adult; Arylamine N-Acetyltransferase; Caffeine; Eva

2000
Applicability of the simple independent action model to epidemiologic studies involving two factors and a dichotomous outcome.
    American journal of epidemiology, 1986, Volume: 123, Issue:1

    Topics: Abortion, Spontaneous; Acquired Immunodeficiency Syndrome; Biometry; Caffeine; Epidemiologic Methods

1986